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$268+ Cheap flights from Greenville to Gainesville (GSP - GNV)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/7. Fares are subject to change and may not be available on all flights or dates of travel.
GSP — GNV
Apr 16 — Apr 231
Thu 4/16
Thu 4/23
1 adult, Economy
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Cheap flight deals from Greenville to Gainesville

Cheapest flights from Greenville to Gainesville
Explore the most affordable flight options available from Greenville to Gainesville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 17, 2026.

This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/297:32 pm
GSP
-
GNV
1 stop5h 01m
American Airlines
Tue 6/27:32 pm
GNV
-
GSP
1 stop4h 20m
American Airlines
Deal found 3/13$387
This American Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:38 am
GSP
-
GNV
1 stop3h 11m
American Airlines
Sun 9/276:36 am
GNV
-
GSP
1 stop5h 19m
American Airlines
Deal found 3/15$407
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/315:20 am
GSP
-
GNV
1 stop5h 55m
American Airlines
Sat 4/45:45 pm
GNV
-
GSP
1 stop6h 09m
American Airlines
Deal found 3/16$447
This Delta deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:42 am
GSP
-
GNV
1 stop3h 42m
Delta
Sun 5/37:03 pm
GNV
-
GSP
1 stop4h 53m
Delta
Deal found 3/14$491
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/215:00 am
GSP
-
GNV
1 stop3h 52m
American Airlines
Sun 8/236:00 am
GNV
-
GSP
2 stops7h 01m
American Airlines
Deal found 3/16$536
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/65:00 am
GSP
-
GNV
1 stop5h 59m
American Airlines
Thu 4/97:59 pm
GNV
-
GSP
1 stop3h 58m
American Airlines
Deal found 3/13$575
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/298:08 am
GSP
-
GNV
1 stop6h 35m
American Airlines
Thu 4/25:45 pm
GNV
-
GSP
1 stop4h 03m
American Airlines
Deal found 3/13$635

Find flight deals from Greenville to Gainesville

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (GSP) to Gainesville (GNV). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 17, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$387
(American Airlines)

One-way from

$268
(Delta)
Provider with most accurate pricing for Greenville-Gainesville Regional flight deals.
Search Deals
Provider most trusted by Cheapflights users for Greenville-Gainesville Regional flights.
Search Deals
From Greenville to Gainesville Regional
Search Deals
One-way flight from Greenville to Gainesville Regional
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to Gainesville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
Use the filters below to find and compare flights from Greenville to Gainesville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvilleGainesville

GSP - GNV

GSPGNV

Greenville

Fri 5/29

7:32 pm-12:33 am

1 stop5h 01m

Gainesville Regional

Tue 6/2

7:32 pm-11:52 pm

1 stop4h 20m

$387

GreenvilleGainesville

GSP - GNV

GSPGNV

Greenville

Fri 8/21

6:45 am-12:22 pm

1 stop5h 37m

Gainesville Regional

Sun 8/23

10:20 am-2:52 pm

1 stop4h 32m

$387

GreenvilleGainesville

GSP - GNV

GSPGNV

Greenville

Tue 3/31

5:20 am-11:15 am

1 stop5h 55m

Gainesville Regional

Sat 4/4

5:45 pm-11:54 pm

1 stop6h 09m

$447
Quickest round-trip

GreenvilleGainesville

GSP - GNV

GSPGNV

Greenville

Fri 5/1

5:42 am-9:24 am

1 stop3h 42m

Gainesville Regional

Sun 5/3

7:03 pm-11:56 pm

1 stop4h 53m

$491

GreenvilleGainesville

GSP - GNV

GSPGNV

Greenville

Mon 4/6

5:00 am-10:59 am

1 stop5h 59m

Gainesville Regional

Thu 4/9

7:59 pm-11:57 pm

1 stop3h 58m

$575

GreenvilleGainesville

GSP - GNV

GSPGNV

Greenville

Sun 3/29

8:08 am-2:43 pm

1 stop6h 35m

Gainesville Regional

Thu 4/2

6:00 am-3:30 pm

2 stops9h 30m

$672
Cheapest one-way
Quickest one-way

GreenvilleGainesville

GSP - GNV

GSPGNV

Greenville

Thu 5/7

8:45 am-12:22 pm

1 stop3h 37m

$268

GreenvilleGainesville

GSP - GNV

GSPGNV

Greenville

Fri 5/1

5:42 am-9:24 am

1 stop3h 42m

$278

GreenvilleGainesville

GSP - GNV

GSPGNV

Greenville

Thu 4/30

5:42 am-9:24 am

1 stop3h 42m

$278

GreenvilleGainesville

GSP - GNV

GSPGNV

Greenville

Fri 5/1

6:45 pm-11:59 pm

1 stop5h 14m

$279

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/12

Showing 1-10 of 11 resultsSorted by cheapest first
1
2

Compare providers for flights from Greenville to Gainesville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to Gainesville in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Greenville-Gainesville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville-Gainesville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville-Gainesville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Greenville-Gainesville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville-Gainesville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Greenville to Gainesville

Have a flexible travel schedule? Discover the best time to fly to Gainesville from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Greenville to Gainesville

What is the cheapest month to book a flight from Greenville to Gainesville?

Currently, April is the cheapest month in which you can book a flight from Greenville to Gainesville (average of $51). Flying from Greenville to Gainesville in May is currently the most expensive (average of $75). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Gainesville

Get insights into the airlines that provide service to Gainesville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Gainesville. Reviews last updated March 17, 2026.
Get a feel of what it's like to fly with Delta from Greenville to Gainesville by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,288 reviews

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Crew

8.5

Overall

7.9

Food

7.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
8,288 reviews
Delta
7.9
Good
8,288 reviews

Boarding

8.1

Comfort

7.9

Entertainment

7.8

Crew

8.5

Overall

7.9

Food

7.2

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Greenville to Gainesville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Greenville to Gainesville?

    For as low as $387, American Airlines can have you in Gainesville from Greenville in 5h 01m. The distance between Greenville and Gainesville is about 359 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Greenville to Gainesville round-trip?

    Flying on Delta is currently your cheapest option to Gainesville, with prices starting at $296.

  • Can I find deals for flights from Greenville to Gainesville that include hotel bookings?

    Yes. In addition to deals on Greenville to Gainesville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to Gainesville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to Gainesville.

  • Can I find deals for business class flights from Greenville to Gainesville?

    Yes. Cheapflights offers flight deals from Greenville to Gainesville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Greenville to Gainesville?

    Currently, April is the cheapest month in which you can book a flight from Greenville to Gainesville (average of $51). Flying from Greenville to Gainesville in May is currently the most expensive (average of $75). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Gainesville?

Book flights to Gainesville if you plan to visit one of these locations
Lake City
Alachua

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Top airline flying from Greenville to Gainesville

Discover the top airline that operate flights from Greenville to Gainesville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$296Average$477FlexibilityNo cancel feeOn-timeN/A

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