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Fort Myers

$82+ Cheap flights from Missouri to Fort Myers (RSW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/31. Fares are subject to change and may not be available on all flights or dates of travel.
MCI — RSW
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from Missouri to Fort Myers

Cheapest flights from Missouri to Fort Myers
Explore the most affordable flight options available from Missouri to Fort Myers. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This Delta deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/233:41 pmSTL - RSW
1 stop6h 16mDelta
Fri 1/237:49 pmRSW - STL
1 stop4h 48mDelta
Deal found 12/16$335
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/165:15 amSTL - RSW
1 stop5h 50mAmerican Airlines
Tue 12/308:10 amRSW - STL
1 stop6h 04mAmerican Airlines
Deal found 12/16$351
This Southwest deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:05 pmSTL - RSW
1 stop4h 20mSouthwest
Fri 1/235:00 pmRSW - STL
Nonstop2h 50mSouthwest
Deal found 12/16$360
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/172:55 pmSGF - RSW
1 stop7h 44mUnited Airlines
Tue 12/238:05 amRSW - SGF
1 stop9h 17mUnited Airlines
Deal found 12/16$369
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/172:25 pmSGF - RSW
2 stops8h 04mAmerican Airlines
Tue 12/233:48 pmRSW - SGF
1 stop7h 16mAmerican Airlines
Deal found 12/16$374
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/205:16 pmSTL - RSW
1 stop5h 41mAmerican Airlines
Sun 12/211:00 pmRSW - STL
1 stop7h 31mAmerican Airlines
Deal found 12/16$390
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/307:05 amSTL - RSW
1 stop6h 53mAmerican Airlines
Tue 1/66:35 pmRSW - STL
1 stop5h 37mAmerican Airlines
Deal found 12/16$415
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1911:33 amSGF - RSW
1 stop8h 07mAmerican Airlines
Sun 12/215:27 pmRSW - SGF
1 stop5h 58mAmerican Airlines
Deal found 12/17$419
This United Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/186:30 amSTL - RSW
1 stop7h 14mUnited Airlines
Sun 12/215:08 pmRSW - STL
1 stop5h 47mUnited Airlines
Deal found 12/15$429
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/185:20 pmMCI - RSW
1 stop6h 08mAmerican Airlines
Thu 12/256:20 amRSW - MCI
1 stop13h 31mAmerican Airlines
Deal found 12/17$430
This Kiwi.com deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2411:33 amMCI - RSW
1 stop5h 45mFrontier
Sat 12/277:35 pmRSW - MCI
2 stops14h 42mFrontier
Deal found 12/16$444
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/244:12 pmMCI - RSW
1 stop7h 08mDelta
Tue 12/303:35 pmRSW - MCI
1 stop6h 30mDelta
Deal found 12/17$451

Find flight deals from Missouri to Fort Myers

Keep the following information in mind while searching for Missouri to Fort Myers flight deals. Data was last updated December 18, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$161
(Kiwi.com)

One-way from

$82
(Frontier)

Popular in

March

Cheapest in

August

Average price

$425
Provider with most accurate pricing for Lambert-St Louis-Fort Myers SW Florida Intl flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Fort Myers SW Florida Intl flights.
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From Missouri to Fort Myers SW Florida Intl
Search Deals
One-way flight from Missouri to Fort Myers SW Florida Intl
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($53 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Fort Myers that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Missouri to Fort Myers that are best for you.

Fly from

Missouri

Fly to

Fort Myers

Route

Depart

Return

Price

SpringfieldFort Myers

SGF - RSW

SGFRSW

Springfield-Branson

Sat 2/21

3:15 pm-10:20 pm

1 stop6h 05m

Fort Myers SW Florida Intl

Sat 2/28

7:00 am-2:40 pm

1 stop8h 40m

$259

SpringfieldFort Myers

SGF - RSW

SGFRSW

Springfield-Branson

Fri 2/6

5:00 pm-12:32 am

1 stop6h 32m

Fort Myers SW Florida Intl

Tue 2/10

6:35 am-11:20 am

1 stop5h 45m

$269

SpringfieldFort Myers

SGF - RSW

SGFRSW

Springfield-Branson

Fri 2/20

4:48 pm-12:28 am

1 stop6h 40m

Fort Myers SW Florida Intl

Mon 2/23

6:00 am-11:03 am

1 stop6h 03m

$279

SpringfieldFort Myers

SGF - RSW

SGFRSW

Springfield-Branson

Fri 1/30

5:00 pm-12:32 am

1 stop6h 32m

Fort Myers SW Florida Intl

Mon 2/2

4:59 pm-9:46 pm

1 stop5h 47m

$279

SpringfieldFort Myers

SGF - RSW

SGFRSW

Springfield-Branson

Thu 2/5

5:39 pm-11:33 pm

1 stop4h 54m

Fort Myers SW Florida Intl

Mon 2/9

6:28 am-11:49 am

1 stop6h 21m

$279

St. LouisFort Myers

STL - RSW

STLRSW

Lambert-St Louis

Tue 1/13

11:22 am-8:02 pm

1 stop7h 40m

Fort Myers SW Florida Intl

Tue 1/20

5:02 pm-10:00 pm

1 stop5h 58m

$293

SpringfieldFort Myers

SGF - RSW

SGFRSW

Springfield-Branson

Sun 4/12

6:50 pm-12:37 am

1 stop4h 47m

Fort Myers SW Florida Intl

Tue 5/19

5:40 pm-10:35 pm

1 stop5h 55m

$294

St. LouisFort Myers

STL - RSW

STLRSW

Lambert-St Louis

Wed 1/21

6:05 am-3:25 pm

2 stops8h 20m

Fort Myers SW Florida Intl

Sun 1/25

6:10 am-2:10 pm

2 stops9h 00m

$309

St. LouisFort Myers

STL - RSW

STLRSW

Lambert-St Louis

Sat 1/24

6:40 am-4:00 pm

1 stop8h 20m

Fort Myers SW Florida Intl

Sat 1/31

8:00 am-9:45 am

Nonstop2h 45m

$309

SpringfieldFort Myers

SGF - RSW

SGFRSW

Springfield-Branson

Sat 4/11

4:00 pm-11:05 pm

1 stop6h 05m

Fort Myers SW Florida Intl

Tue 5/19

5:40 pm-10:35 pm

1 stop5h 55m

$309

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Showing 1-10 of 56 results
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Best time to book a flight from Missouri to Fort Myers

Have a flexible travel schedule? Discover the best time to fly to Fort Myers from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Fort Myers

What is the cheapest month to book a flight from Missouri to Fort Myers?

Currently, October is the cheapest month in which you can book a flight from Missouri to Fort Myers (average of $84). Flying from Missouri to Fort Myers in September is currently the most expensive (average of $183). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to RSW?

Find hourly flight availability from Missouri to Fort Myers. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

One of the essential ways to save on airfare from Missouri to Fort Myers is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight at noon could potentially save you up to 22% on airfare.

What is the cheapest day to fly from Missouri to Fort Myers?

Use this chart to determine the cheapest time to fly round-trip from Missouri to Fort Myers. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Missouri to Fort Myers flight should consider departing on Saturday afternoons when fares are most often at their lowest. Saturday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Missouri to Fort Myers?

Related info for your journey

Find useful and relevant information for your journey from Missouri to Fort Myers. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Fort Myers from Missouri?

    Fort Myers SW Florida Intl (RSW) is the airport you will fly into if you book a flight from Missouri to Fort Myers. It is only a 10.0 mi journey from SW Florida Intl (RSW) to Fort Myers’s city center.

  • How long is the flight from Missouri to Fort Myers?

    A quick flight from Missouri to Fort Myers can take about 6h 05m. United Airlines provides one of the quickest options available for as low as $259. The distance from Missouri to Fort Myers is about 1004 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Missouri to Fort Myers one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $79. However, be on the lookout for offers from Delta and Southwest, as they are both options that can get you from Missouri to Fort Myers for a low price.

  • What are the most popular routes from Missouri to Fort Myers?

    While some choose either Kansas City - Fort Myers SW Florida Intl or Springfield-Branson - Fort Myers SW Florida Intl, Lambert-St Louis - Fort Myers SW Florida Intl is the most popular route from Missouri to Fort Myers.

  • What are the cheapest flights from Missouri to Fort Myers?

    The cheapest flight price from Missouri to Fort Myers is $454. On average you can expect to pay $599. The most popular route, (Lambert-St Louis - Fort Myers SW Florida Intl), can usually be booked for $218.

  • Can I find deals for flights from Missouri to Fort Myers that include hotel bookings?

    Yes. In addition to deals on Missouri to Fort Myers flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Fort Myers?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Fort Myers.

  • Can I find deals for business class flights from Missouri to Fort Myers?

    Yes. Cheapflights offers flight deals from Missouri to Fort Myers by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Fort Myers?

    Currently, October is the cheapest month in which you can book a flight from Missouri to Fort Myers (average of $84). Flying from Missouri to Fort Myers in September is currently the most expensive (average of $183). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Fort Myers?

Book flights to Fort Myers if you plan to visit one of these locations
Sanibel
North Fort Myers
Estero
Lehigh Acres

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Top 4 airlines flying from Missouri to Fort Myers

Discover the top 4 airlines that operate flights from Missouri to Fort Myers. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$150Average$419FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$191Average$426FlexibilityNo cancel feeOn-time63%
DeltaCheapest$192Average$356FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$196Average$449FlexibilityNo cancel feeOn-time71%

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