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Fort Myers

$90+ Cheap flights from Missouri to Fort Myers (RSW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/5. Fares are subject to change and may not be available on all flights or dates of travel.
STL — RSW
Apr 22 — Apr 291
Wed 4/22
Wed 4/29
1 adult, Economy
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Cheap flight deals from Missouri to Fort Myers

Cheapest flights from Missouri to Fort Myers
Explore the most affordable flight options available from Missouri to Fort Myers. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 23, 2026.

This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/292:10 pm
MCI
-
RSW
1 stop5h 05m
Southwest
Wed 5/67:55 am
RSW
-
MCI
1 stop4h 45m
Southwest
Deal found 3/22$291
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2511:44 am
SGF
-
RSW
1 stop8h 11m
American Airlines
Wed 4/295:44 pm
RSW
-
SGF
1 stop7h 12m
American Airlines
Deal found 3/22$299
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/63:00 pm
SGF
-
RSW
1 stop6h 41m
United Airlines
Sat 5/96:45 am
RSW
-
SGF
2 stops10h 41m
United Airlines
Deal found 3/21$311
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1511:47 am
SGF
-
RSW
1 stop8h 08m
American Airlines
Wed 4/226:00 am
RSW
-
SGF
1 stop6h 14m
American Airlines
Deal found 3/19$319
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/241:00 pm
STL
-
RSW
2 stops8h 15m
Southwest
Thu 5/286:35 am
RSW
-
STL
2 stops7h 15m
Southwest
Deal found 3/18$350
This Delta deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/2612:04 pm
STL
-
RSW
1 stop3h 48m
Delta
Tue 3/312:41 pm
RSW
-
STL
1 stop7h 01m
Delta
Deal found 3/23$351
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/41:45 pm
STL
-
RSW
2 stops6h 40m
Southwest
Tue 5/124:15 pm
RSW
-
STL
1 stop4h 35m
Southwest
Deal found 3/22$352
This Delta deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1611:42 am
STL
-
RSW
1 stop6h 07m
Delta
Mon 4/207:56 pm
RSW
-
STL
1 stop4h 40m
Delta
Deal found 3/20$354
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/118:45 am
STL
-
RSW
2 stops9h 00m
Southwest
Sat 4/183:15 pm
RSW
-
STL
1 stop4h 55m
Southwest
Deal found 3/22$356
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/218:25 am
STL
-
RSW
2 stops13h 25m
Southwest
Mon 5/256:20 am
RSW
-
STL
1 stop5h 30m
Southwest
Deal found 3/19$357
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/308:25 am
STL
-
RSW
2 stops13h 25m
Southwest
Sun 5/36:20 am
RSW
-
STL
1 stop5h 45m
Southwest
Deal found 3/22$362
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1112:50 pm
STL
-
RSW
2 stops9h 05m
Southwest
Sat 7/186:20 am
RSW
-
STL
2 stops10h 00m
Southwest
Deal found 3/19$367

Find flight deals from Missouri to Fort Myers

Keep the following information in mind while searching for Missouri to Fort Myers flight deals. Data was last updated March 23, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$291
(Southwest)

One-way from

$90
(Frontier)

Popular in

March

Cheapest in

August

Average price

$473
Provider with most accurate pricing for Lambert-St Louis-Fort Myers SW Florida Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Fort Myers SW Florida Intl flights.
Search Deals
From Missouri to Fort Myers SW Florida Intl
Search Deals
One-way flight from Missouri to Fort Myers SW Florida Intl
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($72 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Fort Myers that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
Use the filters below to find and compare flights from Missouri to Fort Myers that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisFort Myers

STL - RSW

STLRSW

Lambert-St Louis

Fri 5/8

1:45 pm-9:25 pm

2 stops6h 40m

Fort Myers SW Florida Intl

Mon 5/11

6:20 am-3:30 pm

2 stops10h 10m

$350

St. LouisFort Myers

STL - RSW

STLRSW

Lambert-St Louis

Sat 4/11

9:16 am-6:01 pm

1 stop7h 45m

Fort Myers SW Florida Intl

Sat 4/18

5:02 pm-10:28 pm

1 stop6h 26m

$351

St. LouisFort Myers

STL - RSW

STLRSW

Lambert-St Louis

Wed 4/1

7:03 am-12:57 pm

1 stop4h 54m

Fort Myers SW Florida Intl

Sun 4/5

5:30 am-8:47 am

1 stop4h 17m

$351

St. LouisFort Myers

STL - RSW

STLRSW

Lambert-St Louis

Tue 6/16

3:30 pm-10:00 pm

1 stop5h 30m

Fort Myers SW Florida Intl

Mon 6/22

6:15 am-10:20 am

1 stop5h 05m

$351

St. LouisFort Myers

STL - RSW

STLRSW

Lambert-St Louis

Mon 6/15

2:10 pm-9:55 pm

2 stops6h 45m

Fort Myers SW Florida Intl

Fri 6/19

5:10 am-12:10 pm

1 stop8h 00m

$356

St. LouisFort Myers

STL - RSW

STLRSW

Lambert-St Louis

Mon 6/1

2:10 pm-9:25 pm

1 stop6h 15m

Fort Myers SW Florida Intl

Fri 6/5

2:05 pm-8:50 pm

2 stops7h 45m

$356

St. LouisFort Myers

STL - RSW

STLRSW

Lambert-St Louis

Sat 4/11

8:45 am-6:45 pm

2 stops9h 00m

Fort Myers SW Florida Intl

Sat 4/18

3:15 pm-7:10 pm

1 stop4h 55m

$356

St. LouisFort Myers

STL - RSW

STLRSW

Lambert-St Louis

Mon 5/4

1:45 pm-9:25 pm

2 stops6h 40m

Fort Myers SW Florida Intl

Tue 5/12

7:20 am-1:25 pm

2 stops7h 05m

$361

SpringfieldFort Myers

SGF - RSW

SGFRSW

Springfield-Branson

Fri 4/10

6:55 pm-12:36 am

1 stop4h 41m

Fort Myers SW Florida Intl

Fri 4/17

3:00 pm-9:07 pm

1 stop7h 07m

$369
Quickest round-trip

St. LouisFort Myers

STL - RSW

STLRSW

Lambert-St Louis

Fri 4/24

5:25 am-8:50 am

Nonstop2h 25m

Fort Myers SW Florida Intl

Mon 4/27

6:20 am-10:50 am

1 stop5h 30m

$389

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/18

Showing 1-10 of 50 resultsSorted by cheapest first
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Best time to book a flight from Missouri to Fort Myers

Have a flexible travel schedule? Discover the best time to fly to Fort Myers from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Fort Myers

What is the cheapest month to book a flight from Missouri to Fort Myers?

Currently, October is the cheapest month in which you can book a flight from Missouri to Fort Myers (average of $84). Flying from Missouri to Fort Myers in September is currently the most expensive (average of $182). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to RSW?

Find hourly flight availability from Missouri to Fort Myers. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 23, 2026.

One of the essential ways to save on airfare from Missouri to Fort Myers is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the morning could potentially save you up to 26% on airfare.

What is the cheapest day to fly from Missouri to Fort Myers?

Use this chart to determine the cheapest time to fly round-trip from Missouri to Fort Myers. Price data was last updated on March 14, 2026.

Travelers seeking maximum savings on their Missouri to Fort Myers flight should consider departing on Friday evenings when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Fort Myers. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Fort Myers from Missouri?

    Fort Myers SW Florida Intl (RSW) is the airport you will fly into if you book a flight from Missouri to Fort Myers. It is only a 10.0 mi journey from SW Florida Intl (RSW) to Fort Myers’s city center.

  • How popular is this Missouri to Fort Myers flight route?

    The Missouri to Fort Myers SW Florida Intl flight path was viewed by 7 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Missouri to Fort Myers?

    A quick flight from Missouri to Fort Myers can take about 4h 54m. Southwest provides one of the quickest options available for as low as $351. The distance from Missouri to Fort Myers is about 980 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Missouri to Fort Myers one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $79. However, be on the lookout for offers from Delta and Southwest, as they are both options that can get you from Missouri to Fort Myers for a low price.

  • What are the most popular routes from Missouri to Fort Myers?

    While some choose either Kansas City - Fort Myers SW Florida Intl or Springfield-Branson - Fort Myers SW Florida Intl, Lambert-St Louis - Fort Myers SW Florida Intl is the most popular route from Missouri to Fort Myers.

  • What are the cheapest flights from Missouri to Fort Myers?

    The cheapest flight price from Missouri to Fort Myers is $155. On average you can expect to pay $358. The most popular route, (Lambert-St Louis - Fort Myers SW Florida Intl), can usually be booked for $303.

  • Can I find deals for flights from Missouri to Fort Myers that include hotel bookings?

    Yes. In addition to deals on Missouri to Fort Myers flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Fort Myers?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Fort Myers.

  • Can I find deals for business class flights from Missouri to Fort Myers?

    Yes. Cheapflights offers flight deals from Missouri to Fort Myers by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Fort Myers?

    Currently, October is the cheapest month in which you can book a flight from Missouri to Fort Myers (average of $84). Flying from Missouri to Fort Myers in September is currently the most expensive (average of $182). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Fort Myers?

Book flights to Fort Myers if you plan to visit one of these locations
Sanibel
North Fort Myers
Estero
Lehigh Acres

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Top 4 airlines flying from Missouri to Fort Myers

Discover the top 4 airlines that operate flights from Missouri to Fort Myers. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$150Average$403FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$189Average$440FlexibilityNo cancel feeOn-time63%
DeltaCheapest$192Average$377FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$196Average$396FlexibilityNo cancel feeOn-time71%

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