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Fort Myers

$55+ Cheap flights from Missouri to Fort Myers (RSW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/8. Fares are subject to change and may not be available on all flights or dates of travel.
STL — RSW
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Find flight deals from Missouri to Fort Myers

Cheapest flights from Missouri to Fort Myers
Explore the most affordable flight options available from Missouri to Fort Myers. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/56:00 amMCI - RSW
1 stop8h 00mSouthwest
Mon 12/86:30 amRSW - MCI
1 stop7h 55mSouthwest
Deal found 10/28$197
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/111:20 pmSTL - RSW
1 stop5h 59mAmerican Airlines
Tue 11/188:40 amRSW - STL
1 stop5h 34mAmerican Airlines
Deal found 10/27$212
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2411:33 amMCI - RSW
1 stop5h 45mFrontier
Mon 12/297:26 pmRSW - MCI
2 stops39h 42mFrontier
Deal found 10/29$237
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/88:13 amSTL - RSW
1 stop4h 55mAmerican Airlines
Tue 12/96:25 pmRSW - STL
1 stop5h 41mAmerican Airlines
Deal found 10/28$238
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/167:05 amSTL - RSW
1 stop6h 58mDelta
Wed 1/75:35 amRSW - STL
1 stop6h 30mDelta
Deal found 10/28$248
This Southwest deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/65:45 pmSTL - RSW
Nonstop2h 25mSouthwest
Sun 12/145:45 pmRSW - STL
1 stop7h 20mSouthwest
Deal found 10/29$266
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/178:45 amMCI - RSW
1 stop7h 05mSouthwest
Fri 12/56:40 amRSW - MCI
1 stop8h 20mSouthwest
Deal found 10/28$267
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/162:38 pmSTL - RSW
1 stop6h 12mDelta
Thu 1/15:35 amRSW - STL
1 stop4h 23mDelta
Deal found 10/28$269
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/145:12 pmMCI - RSW
1 stop4h 55mDelta
Fri 12/55:38 pmRSW - MCI
1 stop7h 09mDelta
Deal found 10/28$272
This Southwest deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/156:00 amMCI - RSW
1 stop8h 00mSouthwest
Mon 12/224:30 pmRSW - MCI
Nonstop3h 10mSouthwest
Deal found 10/28$276
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/512:13 pmMCI - RSW
1 stop5h 06mFrontier
Sun 12/712:32 pmRSW - MCI
2 stops24h 19mFrontier
Deal found 10/28$277
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/510:42 amSTL - RSW
1 stop6h 37mFrontier
Mon 12/85:45 pmRSW - STL
2 stops29h 48mFrontier
Deal found 10/28$286

Cheap flight deals from Missouri to Fort Myers

Keep the following information in mind while searching for Missouri to Fort Myers flight deals. Data was last updated October 30, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$197
(Southwest)

One-way from

$55
(Priceline)

Popular in

December

Cheapest in

August

Average price

$318
Provider with most accurate pricing for Lambert-St Louis-Fort Myers SW Florida Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Fort Myers SW Florida Intl flights.
Search Deals
From Missouri to Fort Myers SW Florida Intl
Search Deals
One-way flight from Missouri to Fort Myers SW Florida Intl
Search Deals
Highest demand for flights based on searches. 7% potential increase in price ($31 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Fort Myers that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Missouri to Fort Myers that are best for you.

Fly from

Missouri

Fly to

Fort Myers

Route

Depart

Return

Price

Kansas CityFort Myers

MCI - RSW

MCIRSW

Kansas City

Fri 12/5

6:20 am-4:00 pm

2 stops8h 40m

Fort Myers SW Florida Intl

Mon 12/8

6:30 am-1:25 pm

1 stop7h 55m

$202

SpringfieldFort Myers

SGF - RSW

SGFRSW

Springfield-Branson

Fri 1/16

4:29 pm-10:50 pm

1 stop5h 21m

Fort Myers SW Florida Intl

Mon 1/19

6:00 am-12:15 pm

1 stop7h 15m

$259

SpringfieldFort Myers

SGF - RSW

SGFRSW

Springfield-Branson

Fri 1/23

1:28 pm-11:19 pm

1 stop8h 51m

Fort Myers SW Florida Intl

Sun 1/25

7:00 am-1:58 pm

1 stop7h 58m

$259

SpringfieldFort Myers

SGF - RSW

SGFRSW

Springfield-Branson

Fri 1/23

7:00 am-4:35 pm

1 stop8h 35m

Fort Myers SW Florida Intl

Sun 1/25

7:04 am-12:13 pm

1 stop6h 09m

$259

St. LouisFort Myers

STL - RSW

STLRSW

Lambert-St Louis

Thu 1/22

11:35 am-7:50 pm

1 stop7h 15m

Fort Myers SW Florida Intl

Sun 1/25

6:35 am-8:20 am

Nonstop2h 45m

$268

Kansas CityFort Myers

MCI - RSW

MCIRSW

Kansas City

Mon 12/15

6:00 am-3:00 pm

1 stop8h 00m

Fort Myers SW Florida Intl

Mon 12/22

4:30 pm-6:40 pm

Nonstop3h 10m

$276

Kansas CityFort Myers

MCI - RSW

MCIRSW

Kansas City

Mon 1/26

6:23 am-12:22 pm

1 stop4h 59m

Fort Myers SW Florida Intl

Thu 1/29

5:30 pm-10:39 pm

1 stop6h 09m

$277

St. LouisFort Myers

STL - RSW

STLRSW

Lambert-St Louis

Thu 1/22

7:10 am-2:00 pm

1 stop5h 50m

Fort Myers SW Florida Intl

Sun 1/25

5:35 am-8:53 am

1 stop4h 18m

$278

St. LouisFort Myers

STL - RSW

STLRSW

Lambert-St Louis

Wed 1/28

7:10 am-2:00 pm

1 stop5h 50m

Fort Myers SW Florida Intl

Sun 2/1

5:35 am-8:53 am

1 stop4h 18m

$278

St. LouisFort Myers

STL - RSW

STLRSW

Lambert-St Louis

Wed 1/28

10:15 am-4:20 pm

1 stop5h 05m

Fort Myers SW Florida Intl

Sun 2/1

6:10 am-2:10 pm

2 stops9h 00m

$283

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/30

Showing 1-10 of 50 results
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Best time to book a flight from Missouri to Fort Myers

Have a flexible travel schedule? Discover the best time to fly to Fort Myers from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Fort Myers

What is the cheapest month to book a flight from Missouri to Fort Myers?

Currently, October is the cheapest month in which you can book a flight from Missouri to Fort Myers (average of $84). Flying from Missouri to Fort Myers in September is currently the most expensive (average of $183). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to RSW?

Find hourly flight availability from Missouri to Fort Myers. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

One of the essential ways to save on airfare from Missouri to Fort Myers is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight at noon could potentially save you up to 22% on airfare.

What is the cheapest day to fly from Missouri to Fort Myers?

Use this chart to determine the cheapest time to fly round-trip from Missouri to Fort Myers. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Missouri to Fort Myers flight should consider departing on Saturday afternoons when fares are most often at their lowest. Saturday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Fort Myers. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Fort Myers from Missouri?

    Fort Myers SW Florida Intl (RSW) is the airport you will fly into if you book a flight from Missouri to Fort Myers. It is only a 10.0 mi journey from SW Florida Intl (RSW) to Fort Myers’s city center.

  • How popular is this Missouri to Fort Myers flight route?

    The Missouri to Fort Myers SW Florida Intl flight path was viewed by 12 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Missouri to Fort Myers?

    A quick flight from Missouri to Fort Myers can take about 5h 21m. Southwest provides one of the quickest options available for as low as $259. The distance from Missouri to Fort Myers is about 1004 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Missouri to Fort Myers one-way?

    The cheapest airline one-way is Southwest, with whom users have recently found tickets for as low as $64. However, be on the lookout for offers from Delta and American Airlines, as they are both options that can get you from Missouri to Fort Myers for a low price.

  • What are the most popular routes from Missouri to Fort Myers?

    While some choose either Kansas City - Fort Myers SW Florida Intl or Springfield-Branson - Fort Myers SW Florida Intl, Lambert-St Louis - Fort Myers SW Florida Intl is the most popular route from Missouri to Fort Myers.

  • What are the cheapest flights from Missouri to Fort Myers?

    The cheapest flight price from Missouri to Fort Myers is $127. On average you can expect to pay $384. The most popular route, (Lambert-St Louis - Fort Myers SW Florida Intl), can usually be booked for $266.

  • Can I find deals for flights from Missouri to Fort Myers that include hotel bookings?

    Yes. In addition to deals on Missouri to Fort Myers flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Fort Myers?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Fort Myers.

  • Can I find deals for business class flights from Missouri to Fort Myers?

    Yes. Cheapflights offers flight deals from Missouri to Fort Myers by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Fort Myers?

    Currently, October is the cheapest month in which you can book a flight from Missouri to Fort Myers (average of $84). Flying from Missouri to Fort Myers in September is currently the most expensive (average of $183). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Fort Myers?

Book flights to Fort Myers if you plan to visit one of these locations
Sanibel
North Fort Myers
Estero
Lehigh Acres

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Top 4 airlines flying from Missouri to Fort Myers

Discover the top 4 airlines that operate flights from Missouri to Fort Myers. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$150Average$421FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$191Average$420FlexibilityNo cancel feeOn-time63%
DeltaCheapest$194Average$357FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$196Average$445FlexibilityNo cancel feeOn-time71%

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