$183+ Cheap flights from San Diego (SAN) to Florida Keys
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/22. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — EYW
May 9 — May 161
Round-trip
1 adult, Economy
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Find cheap flights from San Diego to Florida Keys with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from San Diego to Florida KeysExplore the most affordable flight options available from San Diego to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 9, 2026.
Explore the most affordable flight options available from San Diego to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:25 pm
SAN
- MIA
2 stops23h 30m
Multiple Airlines
Mon 4/278:42 am
MIA
- SAN
1 stop12h 14m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$362
This CheapOair deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/26:25 am
SAN
- MIA
1 stop20h 29m
Frontier
Fri 7/106:00 am
MIA
- SAN
1 stop20h 53m
Frontier
Deal found 4/9![Frontier logo]()
$365
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/211:38 pm
SAN
- MIA
2 stops12h 55m
Frontier
Sun 5/248:03 pm
MIA
- SAN
1 stop28h 09m
Frontier
Deal found 4/6![Frontier logo]()
$366
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:25 am
SAN
- MIA
1 stop13h 52m
Frontier
Fri 6/196:00 am
MIA
- SAN
1 stop15h 46m
Frontier
Deal found 4/6![Frontier logo]()
$368
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/219:53 pm
SAN
- MIA
2 stops12h 37m
Multiple Airlines
Sun 6/285:05 am
MIA
- SAN
1 stop9h 19m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$369
This Expedia deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/17:00 am
SAN
- MIA
1 stop13h 04m
Frontier
Mon 5/47:00 am
MIA
- SAN
1 stop19h 59m
Frontier
Deal found 4/4![Frontier logo]()
$370
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/99:37 am
SAN
- MIA
1 stop17h 17m
Frontier
Sat 6/208:18 pm
MIA
- SAN
2 stops15h 24m
Frontier
Deal found 4/6![Frontier logo]()
$372
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/710:07 pm
SAN
- MIA
2 stops12h 21m
Frontier
Wed 6/176:00 am
MIA
- SAN
1 stop20h 53m
Frontier
Deal found 4/6![Frontier logo]()
$373
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/167:23 pm
SAN
- MIA
2 stops11h 49m
Multiple Airlines
Sun 4/267:00 am
MIA
- SAN
1 stop20h 11m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$375
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/710:02 pm
SAN
- EYW
1 stop10h 57m
American Airlines
Wed 11/112:50 pm
EYW
- SAN
1 stop9h 21m
American Airlines
Deal found 4/6![American Airlines logo]()
$375
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/267:20 am
SAN
- MIA
1 stop11h 47m
Multiple Airlines
Sat 5/27:00 am
MIA
- SAN
2 stops16h 04m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$376
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:25 pm
SAN
- MIA
1 stop13h 40m
Frontier
Mon 4/278:42 am
MIA
- SAN
1 stop31h 35m
Frontier
Deal found 4/8![Frontier logo]()
$377
Best flights from San Diego to Florida KeysDiscover carefully curated flight deals from San Diego to Florida Keys that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 9, 2026.
Discover carefully curated flight deals from San Diego to Florida Keys that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 9, 2026.
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:15 am
SAN
- EYW
1 stop8h 08m
Delta
Tue 5/1211:48 am
EYW
- SAN
1 stop10h 35m
Delta
Deal found 4/5![Delta logo]()
$375
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/68:15 am
SAN
- EYW
2 stops11h 43m
American Airlines
Tue 5/1211:56 am
EYW
- SAN
1 stop11h 13m
American Airlines
Deal found 4/8![American Airlines logo]()
$400
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/49:40 pm
SAN
- MIA
1 stop10h 50m
Southwest
Tue 5/1212:10 pm
MIA
- SAN
1 stop10h 25m
Southwest
Deal found 4/9![Southwest logo]()
$418
This United Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/2510:40 pm
SAN
- MIA
1 stop9h 44m
United Airlines
Mon 8/38:48 am
MIA
- SAN
1 stop7h 33m
United Airlines
Deal found 4/4![United Airlines logo]()
$432
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2112:09 pm
SAN
- EYW
1 stop19h 18m
Multiple Airlines
Mon 5/2511:52 am
EYW
- SAN
1 stop26h 47m
Multiple Airlines
Deal found 4/4![Multiple Airlines logo]()
$601
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2510:30 pm
SAN
- EYW
1 stop9h 16m
Delta
Wed 4/296:23 pm
EYW
- SAN
1 stop8h 02m
Delta
Deal found 4/6![Delta logo]()
$412
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2512:53 pm
SAN
- EYW
1 stop7h 05m
American Airlines
Wed 4/296:45 am
EYW
- SAN
2 stops10h 20m
American Airlines
Deal found 4/6![American Airlines logo]()
$417
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:45 am
SAN
- MIA
2 stops8h 35m
Southwest
Thu 6/114:00 pm
MIA
- SAN
2 stops10h 05m
Southwest
Deal found 4/6![Southwest logo]()
$442
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2410:30 pm
SAN
- EYW
1 stop9h 54m
United Airlines
Tue 4/283:52 pm
EYW
- SAN
1 stop10h 07m
United Airlines
Deal found 4/9![United Airlines logo]()
$469
This Southwest deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/46:55 am
SAN
- MIA
2 stops8h 30m
Southwest
Thu 5/75:30 am
MIA
- SAN
2 stops8h 50m
Southwest
Deal found 4/7![Southwest logo]()
$447
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1212:53 pm
SAN
- EYW
1 stop7h 05m
American Airlines
Sat 5/166:45 am
EYW
- SAN
1 stop7h 31m
American Airlines
Deal found 4/5![American Airlines logo]()
$460
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/1512:59 pm
SAN
- MIA
1 stop7h 40m
Delta
Wed 7/223:15 pm
MIA
- SAN
1 stop11h 28m
Delta
Deal found 4/5![Delta logo]()
$469
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:30 am
SAN
- MIA
2 stops8h 50m
Southwest
Wed 5/2712:10 pm
MIA
- SAN
2 stops9h 15m
Southwest
Deal found 4/5![Southwest logo]()
$461
This Southwest deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/116:30 am
SAN
- MIA
1 stop8h 00m
Southwest
Mon 7/135:10 am
MIA
- SAN
1 stop6h 30m
Southwest
Deal found 4/4![Southwest logo]()
$465
This Southwest deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/911:55 am
SAN
- MIA
2 stops9h 30m
Southwest
Fri 7/315:10 am
MIA
- SAN
1 stop6h 30m
Southwest
Deal found 4/4![Southwest logo]()
$470
This United Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2910:44 am
SAN
- EYW
1 stop8h 27m
United Airlines
Wed 9/22:20 pm
EYW
- SAN
1 stop11h 29m
United Airlines
Deal found 4/8![United Airlines logo]()
$638
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:15 am
SAN
- EYW
2 stops9h 55m
American Airlines
Sat 6/134:44 pm
EYW
- SAN
2 stops10h 15m
American Airlines
Deal found 4/6![American Airlines logo]()
$617
This Southwest deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/189:35 am
SAN
- MIA
2 stops9h 25m
Southwest
Tue 5/261:25 pm
MIA
- SAN
2 stops9h 30m
Southwest
Deal found 4/4![Southwest logo]()
$497
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/229:15 am
SAN
- MIA
2 stops9h 40m
Southwest
Sat 4/259:30 am
MIA
- SAN
2 stops9h 40m
Southwest
Deal found 4/6![Southwest logo]()
$504
This Southwest deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/308:20 pm
SAN
- MIA
2 stops15h 35m
Southwest
Mon 6/85:35 am
MIA
- SAN
2 stops8h 20m
Southwest
Deal found 4/4![Southwest logo]()
$508
Last-minute flights from San Diego to Florida KeysDiscover last-minute flight deals from San Diego to Florida Keys. Data last updated April 9, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Florida Keys. Data last updated April 9, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:25 am
SAN
- MIA
1 stop20h 24m
Frontier
Wed 4/157:00 am
MIA
- SAN
1 stop19h 06m
Frontier
Deal found 4/4![Frontier logo]()
$381
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/167:23 pm
SAN
- MIA
2 stops11h 49m
Multiple Airlines
Sun 4/267:00 am
MIA
- SAN
1 stop20h 11m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$375
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:25 pm
SAN
- MIA
2 stops23h 30m
Multiple Airlines
Mon 4/278:42 am
MIA
- SAN
1 stop12h 14m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$362
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:25 pm
SAN
- MIA
1 stop13h 40m
Frontier
Mon 4/278:42 am
MIA
- SAN
1 stop31h 35m
Frontier
Deal found 4/8![Frontier logo]()
$377
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:25 pm
SAN
- MIA
1 stop13h 40m
Multiple Airlines
Sun 4/267:00 am
MIA
- SAN
2 stops37h 56m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$384
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/267:20 am
SAN
- MIA
1 stop11h 47m
Multiple Airlines
Sat 5/27:00 am
MIA
- SAN
2 stops16h 04m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$376
This Expedia deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/17:00 am
SAN
- MIA
1 stop13h 04m
Frontier
Mon 5/47:00 am
MIA
- SAN
1 stop19h 59m
Frontier
Deal found 4/4![Frontier logo]()
$370
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/612:53 pm
SAN
- EYW
1 stop7h 05m
American Airlines
Tue 5/126:45 am
EYW
- SAN
1 stop7h 31m
American Airlines
Deal found 4/5![American Airlines logo]()
$375
This American Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/910:05 pm
SAN
- MIA
Nonstop4h 55m
American Airlines
Sat 5/168:40 am
MIA
- SAN
Nonstop5h 36m
American Airlines
Deal found 4/9![American Airlines logo]()
$383
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2012:53 pm
SAN
- MIA
Nonstop5h 06m
American Airlines
Wed 5/277:53 pm
MIA
- SAN
Nonstop5h 27m
American Airlines
Deal found 4/5![American Airlines logo]()
$378
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/211:38 pm
SAN
- MIA
2 stops12h 55m
Frontier
Sun 5/248:03 pm
MIA
- SAN
1 stop28h 09m
Frontier
Deal found 4/6![Frontier logo]()
$366
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2712:36 pm
SAN
- MIA
Nonstop5h 19m
American Airlines
Tue 6/28:55 am
MIA
- SAN
Nonstop5h 23m
American Airlines
Deal found 4/6![American Airlines logo]()
$379
One-way flights from San Diego to Florida KeysSearch for one-way flight options from San Diego to Florida Keys. Find affordable one-way fares based on user searches. Data last updated April 9, 2026.
Search for one-way flight options from San Diego to Florida Keys. Find affordable one-way fares based on user searches. Data last updated April 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/228:00 am
SAN
- EYW
3 stops28h 42m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$183
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/1910:30 pm
SAN
- EYW
1 stop9h 26m
Delta
Deal found 4/4![Delta logo]()
$188
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/712:24 pm
SAN
- MIA
1 stop30h 28m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$218
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/711:55 am
SAN
- MIA
1 stop7h 55m
Southwest
Deal found 4/8![Southwest logo]()
$219
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/237:59 am
SAN
- MIA
1 stop12h 52m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$220
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:25 am
SAN
- MIA
3 stops37h 06m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$221
This CheapOair deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/196:25 am
SAN
- MIA
1 stop20h 29m
Frontier
Deal found 4/5![Frontier logo]()
$222
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:25 am
SAN
- MIA
3 stops24h 37m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$223
This Sun Country Air deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Sun Country Air is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/258:30 am
SAN
- MIA
1 stop23h 12m
Sun Country Air
Deal found 4/7![Sun Country Air logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/59:53 pm
SAN
- MIA
2 stops42h 03m
Frontier
Deal found 4/6![Frontier logo]()
$227
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/94:17 pm
SAN
- MIA
2 stops10h 37m
Frontier
Deal found 4/8![Frontier logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/69:53 pm
SAN
- MIA
1 stop30h 23m
Frontier
Deal found 4/7![Frontier logo]()
$229
Find flight deals from San Diego to Florida Keys
Keep the following information in mind while searching for San Diego to Florida Keys flight deals. Data was last updated April 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $362 (Kiwi.com) |
One-way from | $183 (Kiwi.com) |
Popular in | December |
Cheapest in | January |
Average price | $434 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 9, 2026.
Use the filters below to find and compare flights from San Diego to Florida Keys that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoKey West
SAN - EYW
SANEYW
San Diego
Tue 5/5
6:15 am-5:23 pm
1 stop8h 08m
Key West
Tue 5/12
11:48 am-7:23 pm
1 stop10h 35m
$375
San DiegoKey West
SAN - EYW
SANEYW
San Diego
Wed 5/6
8:15 am-10:58 pm
2 stops11h 43m
Key West
Tue 5/12
11:56 am-8:09 pm
1 stop11h 13m
$400
San DiegoKey West
SAN - EYW
SANEYW
San Diego
Sat 4/25
10:30 pm-10:46 am
1 stop9h 16m
Key West
Wed 4/29
6:23 pm-11:25 pm
1 stop8h 02m
$412
San DiegoKey West
SAN - EYW
SANEYW
San Diego
Sat 4/25
12:53 pm-10:58 pm
1 stop7h 05m
Key West
Wed 4/29
6:45 am-2:05 pm
2 stops10h 20m
$417
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Mon 5/4
9:40 pm-11:30 am
1 stop10h 50m
Miami
Tue 5/12
12:10 pm-7:35 pm
1 stop10h 25m
$418
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Sat 7/25
10:40 pm-11:24 am
1 stop9h 44m
Miami
Mon 8/3
8:48 am-1:21 pm
1 stop7h 33m
$432
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Tue 6/2
6:45 am-6:20 pm
2 stops8h 35m
Miami
Thu 6/11
4:00 pm-11:05 pm
2 stops10h 05m
$442
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Mon 5/4
6:55 am-6:25 pm
2 stops8h 30m
Miami
Thu 5/7
5:30 am-11:20 am
2 stops8h 50m
$447
San DiegoKey West
SAN - EYW
SANEYW
San Diego
Tue 5/12
12:53 pm-10:58 pm
1 stop7h 05m
Key West
Sat 5/16
6:45 am-11:16 am
1 stop7h 31m
$460
San DiegoMiami
SAN - MIA
SANMIA
San Diego
Wed 5/20
6:30 am-6:20 pm
2 stops8h 50m
Miami
Wed 5/27
12:10 pm-6:25 pm
2 stops9h 15m
$461
Showing 1-10 of 36 resultsSorted by cheapest first
Best time to book a flight from San Diego to Florida Keys
Have a flexible travel schedule? Discover the best time to fly to Florida Keys from San Diego with our price prediction graph.
SAN-EYW
SAN-MIA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Florida Keys
SAN-zzEOA
SAN-EYW
SAN-MIA
What is the cheapest month to book a flight from San Diego to Florida Keys?
Currently, August is the cheapest month in which you can book a flight from San Diego to Florida Keys (average of $267). Flying from San Diego to Florida Keys in June is currently the most expensive (average of $550). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Florida Keys
Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated April 9, 2026.
Read through reviews of airlines operating flights from San Diego to Florida Keys, such as Southwest,Alaska Airlines, andDelta. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Overall
8.0
Crew
8.6
Food
7.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Overall
8.0
Crew
8.6
Food
7.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Overall
8.0
Crew
8.6
Food
7.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Overall
8.0
Crew
8.6
Food
7.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Overall
8.0
Crew
8.6
Food
7.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Overall
8.0
Crew
8.6
Food
7.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Related info for your journey
Find useful and relevant information for your journey from San Diego to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for San Diego to Florida Keys
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Complete your trip
Complete your trip to Florida Keys by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Diego to Florida Keys by cabin class
Find flights from San Diego to Florida Keys, based on your preferred cabin class, be it economy, premium economy, business, or first class.
San Diego and Florida Keys flights
Browse other San Diego and Florida Keys flight options. Last updated on April 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
San Diego to Florida Keys flights
Consider these flights traveling from San Diego to Florida Keys.
Top 2 airlines flying from San Diego to Florida Keys
Discover the top 2 airlines that operate flights from San Diego to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$302 | Average$538 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$312 | Average$470 | FlexibilityNo cancel fee | On-time71% |