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Florida Keys

$81+ Cheap flights from San Diego (SAN) to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/26. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — EYW
Aug 26 — Sep 21
Tue 8/26
Tue 9/2
1 adult, Economy
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Cheap flight deals from San Diego to Florida Keys

Keep the following information in mind while searching for San Diego to Florida Keys flight deals. Data was last updated August 21, 2025.

Round-trip from

$215
(Kiwi.com)

One-way from

$81
(CheapOair)

Popular in

December

Cheapest in

September

Average price

$427
From San Diego to Florida Keys
Search Deals
One-way flight from San Diego to Florida Keys
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Highest demand for flights based on searches. 4% potential increase in price ($20 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from San Diego to Florida Keys

Cheapest flights from San Diego to Florida Keys
Explore the most affordable flight options available from San Diego to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 21, 2025.

This CheapOair deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/3012:12 pmSAN - MIA
1 stop15h 18mFrontier
Mon 9/86:00 amMIA - SAN
1 stop20h 53mFrontier
Deal found 8/21$212
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/318:21 amSAN - MIA
1 stop7h 21mMultiple Airlines
Sat 11/86:00 amMIA - SAN
1 stop19h 25mMultiple Airlines
Deal found 8/21$215
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/277:43 pmSAN - MIA
1 stop10h 11mMultiple Airlines
Sat 11/86:00 amMIA - SAN
1 stop19h 25mMultiple Airlines
Deal found 8/21$216
This FlightHub deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2610:20 amSAN - MIA
1 stop11h 24mMultiple Airlines
Wed 10/17:20 pmMIA - SAN
1 stop15h 09mMultiple Airlines
Deal found 8/19$217
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/308:21 amSAN - MIA
2 stops13h 10mMultiple Airlines
Sun 11/97:30 amMIA - SAN
1 stop10h 44mMultiple Airlines
Deal found 8/21$218
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/277:43 pmSAN - MIA
1 stop10h 11mMultiple Airlines
Sun 11/97:30 amMIA - SAN
1 stop10h 44mMultiple Airlines
Deal found 8/21$219
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/25:47 pmSAN - MIA
1 stop9h 32mMultiple Airlines
Thu 11/611:28 amMIA - SAN
2 stops15h 22mMultiple Airlines
Deal found 8/19$220
This Cheapflightsfares deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/286:15 amSAN - MIA
1 stop10h 08mSpirit Airlines
Fri 9/57:23 pmMIA - SAN
1 stop15h 06mSpirit Airlines
Deal found 8/20$221
This Mytrip deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/48:25 amSAN - MIA
1 stop7h 30mSpirit Airlines
Sun 9/75:59 pmMIA - SAN
2 stops16h 30mSpirit Airlines
Deal found 8/21$222
This Mytrip deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/47:47 pmSAN - MIA
2 stops18h 15mSpirit Airlines
Tue 9/98:04 pmMIA - SAN
3 stops30h 30mSpirit Airlines
Deal found 8/19$223
This CheapOair deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/49:03 pmSAN - MIA
1 stop24h 41mFrontier
Sun 9/76:00 amMIA - SAN
1 stop20h 53mFrontier
Deal found 8/21$224
This Mytrip deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/76:15 amSAN - MIA
3 stops26h 31mSpirit Airlines
Wed 9/107:20 pmMIA - SAN
1 stop15h 09mSpirit Airlines
Deal found 8/19$225

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Diego to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 21, 2025.
Use the filters below to find and compare flights from San Diego to Florida Keys that are best for you.

Fly from

San Diego

Fly to

Florida Keys

Route

Depart

Return

Price

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Fri 10/31

8:21 am-6:42 pm

1 stop7h 21m

Miami

Sat 11/8

6:00 am-10:25 pm

1 stop19h 25m

$215

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Mon 10/27

7:43 pm-8:54 am

1 stop10h 11m

Miami

Sat 11/8

6:00 am-10:25 pm

1 stop19h 25m

$216

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Sun 11/2

5:47 pm-6:19 am

1 stop9h 32m

Miami

Mon 11/10

10:30 am-10:14 pm

1 stop14h 44m

$217

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Thu 9/11

9:03 pm-12:44 am

1 stop24h 41m

Miami

Sun 9/14

6:00 am-11:53 pm

1 stop20h 53m

$217

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Thu 10/2

8:25 am-6:55 pm

1 stop7h 30m

Miami

Sat 10/4

6:45 am-10:24 pm

1 stop18h 39m

$217

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Thu 9/18

6:15 am-6:55 pm

1 stop9h 40m

Miami

Wed 9/24

7:20 pm-7:29 am

1 stop15h 09m

$218

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Fri 10/31

7:47 pm-9:41 am

2 stops10h 54m

Miami

Sun 11/9

7:30 am-3:14 pm

1 stop10h 44m

$218

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Mon 10/27

7:43 pm-8:54 am

1 stop10h 11m

Miami

Sun 11/9

7:30 am-3:14 pm

1 stop10h 44m

$219

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Thu 9/4

7:47 pm-5:02 pm

2 stops18h 15m

Miami

Tue 9/9

8:04 pm-11:34 pm

3 stops30h 30m

$223

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Tue 9/16

1:35 pm-6:55 pm

1 stop26h 20m

Miami

Sun 9/21

7:23 pm-11:48 am

1 stop19h 25m

$223

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/20

Showing 1-10 of 31 results
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Best time to book a flight from San Diego to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to Florida Keys

What is the cheapest month to book a flight from San Diego to Florida Keys?

Currently, August is the cheapest month in which you can book a flight from San Diego to Florida Keys (average of $328). Flying from San Diego to Florida Keys in March is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Florida Keys

Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated August 21, 2025.
Read through reviews of airlines operating flights from San Diego to Florida Keys, such as Alaska Airlines, Delta, and American Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Food

7.1

Boarding

8.1

Comfort

7.8

Entertainment

7.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Food

7.1

Boarding

8.1

Comfort

7.8

Entertainment

7.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,981 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Food

7.1

Boarding

8.1

Comfort

7.8

Entertainment

7.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Food

7.1

Boarding

8.1

Comfort

7.8

Entertainment

7.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Spirit Airlines
6.3
Okay
8,029 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Food

7.1

Boarding

8.1

Comfort

7.8

Entertainment

7.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Frontier
5.8
Fair
3,207 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Overall

8.0

Food

7.1

Boarding

8.1

Comfort

7.8

Entertainment

7.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from San Diego to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Diego to Florida Keys?

    Most people fly from San Diego (SAN) if they book a flight from San Diego to Florida Keys. San Diego is conveniently located just 2.6 mi from San Diego’s city center.

  • How long is the flight from San Diego to Florida Keys?

    For as low as $427, Frontier can have you in Florida Keys from San Diego in 9h 12m. There are 2209 mi between San Diego and Florida Keys. This flight may include one or multiple stops.

  • Can I find deals for flights from San Diego to Florida Keys that include hotel bookings?

    Yes. In addition to deals on San Diego to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Diego to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to Florida Keys.

  • Can I find deals for business class flights from San Diego to Florida Keys?

    Yes. Cheapflights offers flight deals from San Diego to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to Florida Keys?

    Currently, August is the cheapest month in which you can book a flight from San Diego to Florida Keys (average of $328). Flying from San Diego to Florida Keys in March is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from San Diego to Florida Keys

Discover the top 2 airlines that operate flights from San Diego to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$278Average$458FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$288Average$540FlexibilityNo cancel feeOn-time71%

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