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Florida Keys

$129+ Cheap flights from San Diego (SAN) to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/2. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — EYW
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
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Find flight deals from San Diego to Florida Keys

Cheapest flights from San Diego to Florida Keys
Explore the most affordable flight options available from San Diego to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This Frontier deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/56:45 amSAN - MIA
1 stop12h 42mFrontier
Sat 12/136:00 amMIA - SAN
1 stop12h 52mFrontier
Deal found 11/6$236
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/54:47 pmSAN - MIA
2 stops15h 25mMultiple Airlines
Mon 12/156:00 amMIA - SAN
1 stop16h 15mMultiple Airlines
Deal found 11/6$237
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/208:39 amSAN - MIA
2 stops35h 29mMultiple Airlines
Tue 11/255:13 pmMIA - SAN
1 stop9h 46mMultiple Airlines
Deal found 11/6$238
This Gotogate deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/155:28 pmSAN - MIA
1 stop9h 51mFrontier
Sun 11/236:15 amMIA - SAN
1 stop20h 44mFrontier
Deal found 11/5$239
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/410:57 amSAN - MIA
2 stops15h 22mFrontier
Fri 12/52:50 pmMIA - SAN
1 stop12h 09mFrontier
Deal found 11/4$240
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/56:45 amSAN - MIA
1 stop12h 42mFrontier
Mon 12/87:05 amMIA - SAN
2 stops15h 10mFrontier
Deal found 11/6$241
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/64:47 pmSAN - MIA
2 stops15h 01mFrontier
Thu 12/113:36 pmMIA - SAN
1 stop11h 15mFrontier
Deal found 11/6$242
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/64:47 pmSAN - MIA
2 stops15h 01mFrontier
Fri 12/122:50 pmMIA - SAN
1 stop12h 09mFrontier
Deal found 11/6$243
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/64:47 pmSAN - MIA
1 stop9h 32mMultiple Airlines
Sat 12/135:05 amMIA - SAN
2 stops18h 02mMultiple Airlines
Deal found 11/6$244
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/208:39 amSAN - MIA
2 stops35h 29mFrontier
Wed 11/266:55 amMIA - SAN
1 stop20h 04mFrontier
Deal found 11/6$246
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/64:47 pmSAN - MIA
2 stops15h 01mFrontier
Sun 12/146:00 amMIA - SAN
1 stop16h 15mFrontier
Deal found 11/6$248
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/236:25 amSAN - MIA
2 stops30h 22mMultiple Airlines
Tue 11/257:12 amMIA - SAN
1 stop19h 47mMultiple Airlines
Deal found 11/6$249

Cheap flight deals from San Diego to Florida Keys

Keep the following information in mind while searching for San Diego to Florida Keys flight deals. Data was last updated November 6, 2025.

Most accurate provider

CheapOair
3 stars

Most trusted provider

CheapOair
3 stars

Round-trip from

$236
(CheapOair)

One-way from

$129
(United Airlines)

Popular in

December

Cheapest in

January

Average price

$459
Provider with most accurate pricing for San Diego-Miami flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Diego-Miami flights.
Search Deals
From San Diego to Florida Keys
Search Deals
One-way flight from San Diego to Florida Keys
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($11 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Diego to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from San Diego to Florida Keys that are best for you.

Fly from

San Diego

Fly to

Florida Keys

Route

Depart

Return

Price

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Wed 12/3

6:15 am-6:26 pm

1 stop9h 11m

Miami

Thu 12/11

2:11 pm-9:18 pm

1 stop10h 07m

$257

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Wed 12/3

2:19 pm-12:46 am

1 stop7h 27m

Miami

Wed 12/10

6:30 pm-11:35 pm

1 stop8h 05m

$257

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Tue 1/27

6:50 am-8:05 pm

2 stops10h 15m

Miami

Thu 1/29

6:55 am-1:20 pm

2 stops9h 25m

$284

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Wed 1/21

6:50 am-8:05 pm

2 stops10h 15m

Miami

Sun 1/25

7:00 am-1:35 pm

2 stops9h 35m

$308

San DiegoKey West

SAN - EYW

SANEYW

San Diego

Fri 1/23

1:27 pm-11:56 pm

1 stop7h 29m

Key West

Tue 1/27

2:58 pm-8:41 pm

1 stop8h 43m

$309

San DiegoKey West

SAN - EYW

SANEYW

San Diego

Thu 1/29

9:21 am-11:56 pm

2 stops11h 35m

Key West

Mon 2/2

6:06 am-12:27 pm

1 stop9h 21m

$314

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Mon 12/22

10:30 pm-10:30 am

1 stop9h 00m

Miami

Wed 12/31

6:20 am-11:05 am

1 stop7h 45m

$334

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Tue 12/23

6:25 am-7:30 pm

2 stops10h 05m

Miami

Thu 1/1

6:05 am-7:15 pm

1 stop16h 10m

$345

San DiegoMiami

SAN - MIA

SANMIA

San Diego

Tue 12/16

8:00 pm-10:49 am

2 stops11h 49m

Miami

Tue 2/10

9:00 am-8:49 pm

2 stops14h 49m

$347

San DiegoKey West

SAN - EYW

SANEYW

San Diego

Thu 1/1

6:15 am-4:30 pm

1 stop7h 15m

Key West

Sat 1/10

6:06 am-12:27 pm

1 stop9h 21m

$349

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/5

Showing 1-10 of 38 results
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Best time to book a flight from San Diego to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to Florida Keys

What is the cheapest month to book a flight from San Diego to Florida Keys?

Currently, April is the cheapest month in which you can book a flight from San Diego to Florida Keys (average of $160). Flying from San Diego to Florida Keys in July is currently the most expensive (average of $438). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Florida Keys

Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated November 6, 2025.
Read through reviews of airlines operating flights from San Diego to Florida Keys, such as Alaska Airlines, Delta, and American Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
11,246 reviews

Food

7.1

Entertainment

7.0

Comfort

7.8

Crew

8.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Alaska Airlines
8.0
Very good
11,246 reviews
Alaska Airlines
8.0
Very good
11,246 reviews

Food

7.1

Entertainment

7.0

Comfort

7.8

Crew

8.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Delta
7.9
Good
8,001 reviews
Alaska Airlines
8.0
Very good
11,246 reviews

Food

7.1

Entertainment

7.0

Comfort

7.8

Crew

8.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
American Airlines
7.2
Good
11,040 reviews
Alaska Airlines
8.0
Very good
11,246 reviews

Food

7.1

Entertainment

7.0

Comfort

7.8

Crew

8.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Spirit Airlines
6.3
Okay
8,122 reviews
Alaska Airlines
8.0
Very good
11,246 reviews

Food

7.1

Entertainment

7.0

Comfort

7.8

Crew

8.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.
Frontier
5.8
Fair
3,116 reviews
Alaska Airlines
8.0
Very good
11,246 reviews

Food

7.1

Entertainment

7.0

Comfort

7.8

Crew

8.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
6.0
Good

Hannah,Aug 2025

SFO - SAN

Ticket said TSA pre check, but then the TSA agent said that Alaska Airlines has not actually entered the pre check information for the ticket, so I had to use regular security. During boarding, I have a disability and need to board early. The Alaska Airlines employee announced disability boarding, but then immediately announced 2 other groups to board, so I still had to fight the crowds. On the plane, the stewardess was brusk and rude. Seats were very uncomfortable, especially on lower back.

Related info for your journey

Find useful and relevant information for your journey from San Diego to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Diego to Florida Keys?

    Most people fly from San Diego (SAN) if they book a flight from San Diego to Florida Keys. San Diego is conveniently located just 2.6 mi from San Diego’s city center.

  • How long is the flight from San Diego to Florida Keys?

    For as low as $309, Delta can have you in Florida Keys from San Diego in 7h 29m. There are 2209 mi between San Diego and Florida Keys. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from San Diego to Florida Keys one-way?

    The cheapest airlines for a one-way flight from San Diego to Florida Keys are United Airlines ($129), American Airlines ($129), and Frontier ($133).

  • Can I find deals for flights from San Diego to Florida Keys that include hotel bookings?

    Yes. In addition to deals on San Diego to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Diego to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to Florida Keys.

  • Can I find deals for business class flights from San Diego to Florida Keys?

    Yes. Cheapflights offers flight deals from San Diego to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to Florida Keys?

    Currently, April is the cheapest month in which you can book a flight from San Diego to Florida Keys (average of $160). Flying from San Diego to Florida Keys in July is currently the most expensive (average of $438). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from San Diego to Florida Keys

Discover the top 2 airlines that operate flights from San Diego to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$278Average$433FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$309Average$546FlexibilityNo cancel feeOn-time71%

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