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$217+ Cheap flights from Roanoke (ROA) to Florida Keys

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/22. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — EYW
Jan 22 — Jan 291
Thu 1/22
Thu 1/29
1 adult, Economy
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Cheap flight deals from Roanoke to Florida Keys

Cheapest flights from Roanoke to Florida Keys
Explore the most affordable flight options available from Roanoke to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.

This Delta deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/212:30 pmROA - MIA
1 stop6h 27mDelta
Sun 12/286:00 amMIA - ROA
1 stop4h 37mDelta
Deal found 12/20$354
This Delta deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2211:17 amROA - MIA
1 stop4h 37mDelta
Thu 12/252:04 pmMIA - ROA
1 stop5h 22mDelta
Deal found 12/21$369
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:00 amROA - MIA
1 stop7h 10mAmerican Airlines
Sun 12/286:00 amMIA - ROA
1 stop4h 31mAmerican Airlines
Deal found 12/21$502
This United Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2210:52 amROA - MIA
2 stops11h 48mUnited Airlines
Thu 12/251:00 pmMIA - ROA
1 stop5h 51mUnited Airlines
Deal found 12/21$525
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/277:07 pmROA - MIA
1 stop5h 40mAmerican Airlines
Tue 12/307:00 amMIA - ROA
1 stop7h 22mAmerican Airlines
Deal found 12/21$536
This American Airlines deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:47 pmROA - MIA
1 stop5h 47mAmerican Airlines
Sun 1/46:00 amMIA - ROA
1 stop4h 31mAmerican Airlines
Deal found 12/22$551
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/277:07 pmROA - MIA
2 stops12h 07mAmerican Airlines
Sun 12/289:59 amMIA - ROA
1 stop6h 45mAmerican Airlines
Deal found 12/21$564
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:14 amROA - MIA
1 stop5h 14mAmerican Airlines
Fri 1/26:00 amMIA - ROA
1 stop4h 31mAmerican Airlines
Deal found 12/21$584
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/296:00 amROA - MIA
1 stop5h 09mAmerican Airlines
Fri 1/26:00 amMIA - ROA
1 stop4h 31mAmerican Airlines
Deal found 12/21$677
This United Airlines deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/217:55 pmROA - MIA
1 stop5h 13mUnited Airlines
Sun 12/286:20 amMIA - ROA
2 stops14h 38mUnited Airlines
Deal found 12/20$693
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/267:07 pmROA - MIA
1 stop5h 40mAmerican Airlines
Tue 12/307:00 amMIA - ROA
1 stop7h 22mAmerican Airlines
Deal found 12/21$735

Find flight deals from Roanoke to Florida Keys

Keep the following information in mind while searching for Roanoke to Florida Keys flight deals. Data was last updated December 23, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$249
(American Airlines)

One-way from

$239
(Delta)

Popular in

April

Cheapest in

November

Average price

$495
Provider with most accurate pricing for Roanoke-Miami flight deals.
Search Deals
Provider most trusted by Cheapflights users for Roanoke-Miami flights.
Search Deals
From Roanoke to Florida Keys
Search Deals
One-way flight from Roanoke to Florida Keys
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($74 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from Roanoke to Florida Keys that are best for you.

Fly from

Roanoke

Fly to

Florida Keys

Route

Depart

Return

Price

RoanokeKey West

ROA - EYW

ROAEYW

Roanoke

Thu 1/22

3:45 pm-9:37 pm

1 stop5h 52m

Key West

Thu 1/29

3:46 pm-3:03 pm

1 stop23h 17m

$217

RoanokeMiami

ROA - MIA

ROAMIA

Roanoke

Tue 1/27

7:59 pm-12:51 am

1 stop4h 52m

Miami

Tue 2/3

3:45 pm-11:06 pm

1 stop7h 21m

$249

RoanokeMiami

ROA - MIA

ROAMIA

Roanoke

Thu 1/15

1:56 pm-9:10 pm

1 stop7h 14m

Miami

Mon 1/26

7:07 am-1:31 pm

1 stop6h 24m

$249

RoanokeMiami

ROA - MIA

ROAMIA

Roanoke

Tue 1/27

6:00 am-10:40 am

1 stop4h 40m

Miami

Sat 1/31

5:50 am-10:39 am

1 stop4h 49m

$249

RoanokeKey West

ROA - EYW

ROAEYW

Roanoke

Thu 1/22

1:56 pm-11:56 pm

2 stops10h 00m

Key West

Thu 1/29

4:04 pm-10:53 pm

1 stop6h 49m

$294

RoanokeMiami

ROA - MIA

ROAMIA

Roanoke

Wed 4/8

3:13 pm-10:26 pm

1 stop7h 13m

Miami

Thu 4/16

6:00 am-10:28 am

1 stop4h 28m

$294

RoanokeMiami

ROA - MIA

ROAMIA

Roanoke

Fri 4/24

7:37 pm-12:50 am

1 stop5h 13m

Miami

Sat 5/2

6:00 am-10:28 am

1 stop4h 28m

$294

RoanokeMiami

ROA - MIA

ROAMIA

Roanoke

Tue 4/7

6:00 am-10:39 am

1 stop4h 39m

Miami

Fri 4/17

7:30 pm-12:23 am

1 stop4h 53m

$294

RoanokeMiami

ROA - MIA

ROAMIA

Roanoke

Fri 1/9

3:30 pm-9:10 pm

1 stop5h 40m

Miami

Sun 1/11

8:10 am-4:59 pm

1 stop8h 49m

$309

RoanokeKey West

ROA - EYW

ROAEYW

Roanoke

Tue 1/6

5:14 pm-9:47 pm

1 stop4h 33m

Key West

Sat 1/10

2:04 pm-8:31 pm

1 stop6h 27m

$319

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/21

Showing 1-10 of 24 results
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Best time to book a flight from Roanoke to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to Florida Keys

What is the cheapest month to book a flight from Roanoke to Florida Keys?

Currently, February is the cheapest month in which you can book a flight from Roanoke to Florida Keys (average of $208). Flying from Roanoke to Florida Keys in November is currently the most expensive (average of $413). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Florida Keys

Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated December 23, 2025.
Read through reviews of airlines operating flights from Roanoke to Florida Keys, such as Delta and American Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,014 reviews

Boarding

8.1

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Delta
7.9
Good
8,014 reviews
Delta
7.9
Good
8,014 reviews

Boarding

8.1

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
American Airlines
7.2
Good
11,054 reviews
Delta
7.9
Good
8,014 reviews

Boarding

8.1

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

7.9

Crew

8.5

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from Roanoke to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Roanoke to Florida Keys?

    Roanoke (ROA), located 4.2 mi from the city center, is the airport you fly out of when you book flights from Roanoke to Florida Keys.

  • How long is the flight from Roanoke to Florida Keys?

    A quick flight from Roanoke to Florida Keys can take about 4h 52m. Allegiant Air provides one of the quickest options available for as low as $249. The distance from Roanoke to Florida Keys is about 796 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Roanoke to Florida Keys that include hotel bookings?

    Yes. In addition to deals on Roanoke to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to Florida Keys.

  • Can I find deals for business class flights from Roanoke to Florida Keys?

    Yes. Cheapflights offers flight deals from Roanoke to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to Florida Keys?

    Currently, February is the cheapest month in which you can book a flight from Roanoke to Florida Keys (average of $208). Flying from Roanoke to Florida Keys in November is currently the most expensive (average of $413). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Roanoke to Florida Keys

Discover the top 2 airlines that operate flights from Roanoke to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$248Average$378FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$468FlexibilityNo cancel feeOn-time71%

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