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$166+ Cheap flights from Roanoke (ROA) to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/28. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — EYW
May 5 — May 121
Mon 5/5
Mon 5/12
1 adult, Economy
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Cheap flight deals from Roanoke to Florida Keys

Keep the following information in mind while searching for Roanoke to Florida Keys flight deals. Data was last updated April 30, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$245
(Lucky2Go)

One-way from

$166
(Delta)

Popular in

December

Cheapest in

August

Average price

$568
Provider with most accurate pricing for Roanoke-Miami flight deals.
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Provider most trusted by Cheapflights users for Roanoke-Miami flights.
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From Roanoke to Florida Keys
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One-way flight from Roanoke to Florida Keys
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Highest demand for flights based on searches. 8% potential increase in price ($44 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Roanoke to Florida Keys

Cheapest flights from Roanoke to Florida Keys
Explore the most affordable flight options available from Roanoke to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.

This Lucky2Go deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lucky2Go is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/129:42 pmROA - EYW
1 stop11h 51mAllegiant Air
Thu 6/198:53 amEYW - ROA
1 stop12h 02mAllegiant Air
Deal found 4/27$245
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/78:11 pmROA - MIA
1 stop4h 18mAmerican Airlines
Sun 6/159:00 amMIA - ROA
1 stop7h 17mAmerican Airlines
Deal found 4/29$249
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/309:55 amROA - EYW
1 stop7h 20mDelta
Sat 9/66:00 pmEYW - ROA
1 stop5h 51mDelta
Deal found 4/28$249
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/306:00 amROA - EYW
2 stops10h 20mAmerican Airlines
Sat 9/67:21 pmEYW - ROA
1 stop4h 16mAmerican Airlines
Deal found 4/28$284
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/912:40 pmROA - MIA
1 stop5h 53mDelta
Mon 5/125:35 amMIA - ROA
1 stop4h 56mDelta
Deal found 4/29$309
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/126:20 amROA - EYW
2 stops25h 40mUnited Airlines
Thu 6/196:45 pmEYW - ROA
2 stops28h 50mUnited Airlines
Deal found 4/28$386
This United Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/46:20 amROA - MIA
1 stop5h 29mUnited Airlines
Thu 7/1012:20 pmMIA - ROA
1 stop8h 44mUnited Airlines
Deal found 4/29$394

Cheapflights Fare Finder

Customize your flight search to find flights from Roanoke to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
Use the filters below to find and compare flights from Roanoke to Florida Keys that are best for you.

Fly from

Roanoke

Fly to

Florida Keys

Route

Depart

Return

Price

RoanokeKey West

ROA - EYW

ROAEYW

Roanoke

Thu 6/12

9:42 pm-9:33 am

1 stop11h 51m

Key West

Thu 6/19

8:53 am-8:55 pm

1 stop12h 02m

$245

RoanokeMiami

ROA - MIA

ROAMIA

Roanoke

Sat 6/7

8:11 pm-12:29 am

1 stop4h 18m

Miami

Sun 6/15

9:00 am-4:17 pm

1 stop7h 17m

$249

RoanokeKey West

ROA - EYW

ROAEYW

Roanoke

Tue 5/27

6:00 am-10:51 am

1 stop4h 51m

Key West

Tue 6/3

6:25 pm-12:04 am

1 stop5h 39m

$279

RoanokeMiami

ROA - MIA

ROAMIA

Roanoke

Fri 5/9

12:40 pm-6:33 pm

1 stop5h 53m

Miami

Mon 5/12

5:35 am-10:31 am

1 stop4h 56m

$309

RoanokeKey West

ROA - EYW

ROAEYW

Roanoke

Tue 5/27

8:30 am-4:52 pm

2 stops8h 22m

Key West

Tue 6/3

5:24 pm-11:48 pm

1 stop6h 24m

$334

RoanokeKey West

ROA - EYW

ROAEYW

Roanoke

Thu 6/12

6:20 am-8:00 am

2 stops25h 40m

Key West

Thu 6/19

6:45 pm-11:35 pm

2 stops28h 50m

$386

RoanokeMiami

ROA - MIA

ROAMIA

Roanoke

Fri 7/4

6:20 am-11:49 am

1 stop5h 29m

Miami

Thu 7/10

12:20 pm-9:04 pm

1 stop8h 44m

$394

RoanokeMiami

ROA - MIA

ROAMIA

Roanoke

Wed 5/28

7:49 pm-12:37 am

1 stop4h 48m

$166

RoanokeMiami

ROA - MIA

ROAMIA

Roanoke

Wed 5/28

7:40 pm-11:04 am

2 stops15h 24m

$298

RoanokeMiami

ROA - MIA

ROAMIA

Roanoke

Fri 6/6

2:37 pm-8:49 pm

1 stop6h 12m

$299

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/28

Best time to book a flight from Roanoke to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to Florida Keys

What is the cheapest month to book a flight from Roanoke to Florida Keys?

Currently, August is the cheapest month in which you can book a flight from Roanoke to Florida Keys (average of $328). Flying from Roanoke to Florida Keys in March is currently the most expensive (average of $493). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Florida Keys by month

Plan your trip to Florida Keys by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Florida Keys ranges from 1.6 - 9.9 inches per month. September is typically the wettest month, when rainfall can reach 9.9 in. January is typically the driest time to visit Florida Keys when rainfall is around 1.6 in.

Temperature in Florida Keys by month

Plan your trip to Florida Keys by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Florida Keys, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 68.0 F).

Reviews of airlines servicing Florida Keys

Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated April 30, 2025.
Get a feel of what it's like to fly with Delta, United Airlines and Allegiant Air from Roanoke to Florida Keys by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,929 reviews

Entertainment

7.9

Comfort

7.9

Crew

8.5

Overall

8.0

Boarding

8.2

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Delta
8.0
Very good
7,929 reviews
Delta
8.0
Very good
7,929 reviews

Entertainment

7.9

Comfort

7.9

Crew

8.5

Overall

8.0

Boarding

8.2

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
United Airlines
7.4
Good
8,696 reviews
Delta
8.0
Very good
7,929 reviews

Entertainment

7.9

Comfort

7.9

Crew

8.5

Overall

8.0

Boarding

8.2

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Allegiant Air
7.3
Good
734 reviews
Delta
8.0
Very good
7,929 reviews

Entertainment

7.9

Comfort

7.9

Crew

8.5

Overall

8.0

Boarding

8.2

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,929 reviews

Entertainment

7.9

Comfort

7.9

Crew

8.5

Overall

8.0

Boarding

8.2

Food

7.3

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from Roanoke to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Roanoke to Florida Keys?

    Roanoke (ROA), located 4.2 mi from the city center, is the airport you fly out of when you book flights from Roanoke to Florida Keys.

  • What are the cheapest airlines to fly from Roanoke to Florida Keys one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $166. United Airlines flights start at $298 while deals on American Airlines start at $299 one-way.

  • Can I find deals for flights from Roanoke to Florida Keys that include hotel bookings?

    Yes. In addition to deals on Roanoke to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to Florida Keys.

  • Can I find deals for business class flights from Roanoke to Florida Keys?

    Yes. Cheapflights offers flight deals from Roanoke to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to Florida Keys?

    Currently, August is the cheapest month in which you can book a flight from Roanoke to Florida Keys (average of $328). Flying from Roanoke to Florida Keys in March is currently the most expensive (average of $493). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Roanoke to Florida Keys

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Roanoke to Florida Keys

Discover the top 2 airlines that operate flights from Roanoke to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$248Average$393FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$303Average$488FlexibilityNo cancel feeOn-time71%

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