$140+ Cheap flights from Roanoke (ROA) to Florida Keys
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/18. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — EYW
May 11 — May 181
Round-trip
1 adult, Economy
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Find cheap flights from Roanoke to Florida Keys with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Roanoke to Florida KeysExplore the most affordable flight options available from Roanoke to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 11, 2026.
Explore the most affordable flight options available from Roanoke to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 11, 2026.
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:58 pm
ROA
- MIA
1 stop4h 49m
American Airlines
Sat 5/306:20 am
MIA
- ROA
1 stop4h 25m
American Airlines
Deal found 4/8![American Airlines logo]()
$280
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/167:58 pm
ROA
- MIA
1 stop4h 49m
American Airlines
Tue 6/236:20 am
MIA
- ROA
1 stop4h 25m
American Airlines
Deal found 4/8![American Airlines logo]()
$281
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/182:33 pm
ROA
- MIA
1 stop8h 15m
American Airlines
Sat 7/256:56 am
MIA
- ROA
1 stop6h 55m
American Airlines
Deal found 4/7![American Airlines logo]()
$293
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:05 am
ROA
- MIA
1 stop7h 19m
Delta
Tue 7/286:00 pm
MIA
- ROA
1 stop5h 50m
Delta
Deal found 4/7![Delta logo]()
$301
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/47:05 am
ROA
- MIA
1 stop7h 20m
Delta
Sat 5/96:00 am
MIA
- ROA
1 stop4h 30m
Delta
Deal found 4/6![Delta logo]()
$312
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/123:48 pm
ROA
- EYW
1 stop17h 21m
Multiple Airlines
Sun 5/101:57 pm
EYW
- ROA
1 stop26h 07m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$315
This Delta deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:30 pm
ROA
- MIA
1 stop5h 17m
Delta
Sat 5/236:00 am
MIA
- ROA
1 stop4h 30m
Delta
Deal found 4/10![Delta logo]()
$322
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/123:48 pm
ROA
- EYW
1 stop17h 21m
Multiple Airlines
Thu 5/711:04 am
EYW
- ROA
1 stop8h 44m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$322
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/127:05 am
ROA
- EYW
1 stop6h 37m
Delta
Tue 5/192:32 pm
EYW
- ROA
1 stop8h 28m
Delta
Deal found 4/6![Delta logo]()
$323
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/258:10 am
ROA
- EYW
2 stops10h 37m
American Airlines
Wed 7/297:29 pm
EYW
- ROA
1 stop4h 26m
American Airlines
Deal found 4/10![American Airlines logo]()
$328
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:05 am
ROA
- MIA
1 stop7h 19m
Delta
Thu 7/233:29 pm
MIA
- ROA
1 stop8h 02m
Delta
Deal found 4/7![Delta logo]()
$332
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1212:58 pm
ROA
- EYW
2 stops10h 00m
American Airlines
Tue 5/196:45 am
EYW
- ROA
2 stops10h 48m
American Airlines
Deal found 4/6![American Airlines logo]()
$333
Best flights from Roanoke to Florida KeysDiscover carefully curated flight deals from Roanoke to Florida Keys that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 11, 2026.
Discover carefully curated flight deals from Roanoke to Florida Keys that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 11, 2026.
This Delta deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:30 pm
ROA
- MIA
1 stop5h 17m
Delta
Sat 5/239:00 am
MIA
- ROA
1 stop8h 20m
Delta
Deal found 4/9![Delta logo]()
$322
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/258:10 am
ROA
- EYW
2 stops10h 37m
American Airlines
Wed 7/297:29 pm
EYW
- ROA
1 stop4h 26m
American Airlines
Deal found 4/10![American Airlines logo]()
$328
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/218:37 am
ROA
- MIA
1 stop6h 28m
United Airlines
Sat 4/258:55 am
MIA
- ROA
1 stop8h 07m
United Airlines
Deal found 4/6![United Airlines logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/182:38 pm
ROA
- EYW
2 stops19h 03m
Allegiant Air
Sun 6/219:16 pm
EYW
- ROA
1 stop18h 02m
Allegiant Air
Deal found 4/10![Allegiant Air logo]()
$437
This Delta deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:00 am
ROA
- MIA
1 stop6h 56m
Delta
Sat 5/96:00 am
MIA
- ROA
1 stop4h 30m
Delta
Deal found 4/9![Delta logo]()
$322
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/127:05 am
ROA
- EYW
1 stop6h 37m
Delta
Tue 5/192:32 pm
EYW
- ROA
1 stop8h 28m
Delta
Deal found 4/6![Delta logo]()
$323
This American Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/268:10 am
ROA
- EYW
2 stops10h 39m
American Airlines
Tue 6/27:29 pm
EYW
- ROA
1 stop4h 18m
American Airlines
Deal found 4/9![American Airlines logo]()
$391
This Delta deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:00 am
ROA
- MIA
1 stop6h 56m
Delta
Mon 5/187:39 pm
MIA
- ROA
1 stop4h 55m
Delta
Deal found 4/9![Delta logo]()
$363
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/227:57 pm
ROA
- MIA
1 stop4h 58m
Delta
Sat 7/256:00 pm
MIA
- ROA
1 stop5h 50m
Delta
Deal found 4/7![Delta logo]()
$367
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/810:34 am
ROA
- MIA
1 stop5h 42m
United Airlines
Wed 5/136:10 pm
MIA
- ROA
1 stop5h 34m
United Airlines
Deal found 4/9![United Airlines logo]()
$497
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/227:05 am
ROA
- MIA
2 stops17h 50m
Delta
Tue 7/287:16 pm
MIA
- ROA
1 stop4h 34m
Delta
Deal found 4/7![Delta logo]()
$389
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/262:13 pm
ROA
- MIA
1 stop8h 04m
United Airlines
Wed 9/3012:15 pm
MIA
- ROA
1 stop8h 24m
United Airlines
Deal found 4/6![United Airlines logo]()
$519
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:00 am
ROA
- EYW
1 stop5h 16m
American Airlines
Tue 6/27:29 pm
EYW
- ROA
1 stop4h 18m
American Airlines
Deal found 4/7![American Airlines logo]()
$530
This Delta deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:00 am
ROA
- EYW
1 stop4h 53m
Delta
Tue 6/26:19 pm
EYW
- ROA
1 stop6h 15m
Delta
Deal found 4/9![Delta logo]()
$411
This Delta deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am
ROA
- EYW
1 stop4h 58m
Delta
Thu 10/156:00 pm
EYW
- ROA
1 stop5h 49m
Delta
Deal found 4/8![Delta logo]()
$426
This Delta deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:00 am
ROA
- EYW
1 stop4h 58m
Delta
Sat 10/176:00 pm
EYW
- ROA
1 stop5h 49m
Delta
Deal found 4/8![Delta logo]()
$431
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/187:35 am
ROA
- MIA
2 stops17h 20m
Delta
Mon 7/273:29 pm
MIA
- ROA
1 stop8h 02m
Delta
Deal found 4/7![Delta logo]()
$518
This Delta deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:00 am
ROA
- EYW
2 stops12h 43m
Delta
Tue 10/136:00 pm
EYW
- ROA
1 stop5h 49m
Delta
Deal found 4/8![Delta logo]()
$520
Last-minute flights from Roanoke to Florida KeysDiscover last-minute flight deals from Roanoke to Florida Keys. Data last updated April 11, 2026 and is based on user searches.
Discover last-minute flight deals from Roanoke to Florida Keys. Data last updated April 11, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/123:48 pm
ROA
- EYW
1 stop17h 21m
Multiple Airlines
Sun 5/101:57 pm
EYW
- ROA
1 stop26h 07m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$315
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/123:48 pm
ROA
- EYW
1 stop17h 21m
Multiple Airlines
Thu 5/711:04 am
EYW
- ROA
1 stop8h 44m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$322
This United Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/242:04 pm
ROA
- MIA
1 stop8h 41m
United Airlines
Tue 4/284:18 pm
MIA
- ROA
1 stop8h 19m
United Airlines
Deal found 4/10![United Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/255:18 pm
ROA
- EYW
1 stop5h 18m
American Airlines
Wed 4/2911:56 am
EYW
- ROA
1 stop7h 09m
American Airlines
Deal found 4/10![American Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/47:05 am
ROA
- MIA
1 stop7h 20m
Delta
Sat 5/96:00 am
MIA
- ROA
1 stop4h 30m
Delta
Deal found 4/6![Delta logo]()
$312
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/78:09 am
ROA
- MIA
1 stop7h 41m
American Airlines
Mon 5/187:05 am
MIA
- ROA
1 stop5h 28m
American Airlines
Deal found 4/6![American Airlines logo]()
$343
This Delta deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/97:05 am
ROA
- MIA
1 stop7h 06m
Delta
Sat 5/166:00 am
MIA
- ROA
1 stop4h 30m
Delta
Deal found 4/7![Delta logo]()
$301
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/127:05 am
ROA
- EYW
1 stop6h 37m
Delta
Tue 5/192:32 pm
EYW
- ROA
1 stop8h 28m
Delta
Deal found 4/6![Delta logo]()
$323
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1212:58 pm
ROA
- EYW
2 stops10h 00m
American Airlines
Tue 5/196:45 am
EYW
- ROA
2 stops10h 48m
American Airlines
Deal found 4/6![American Airlines logo]()
$333
This Delta deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:30 pm
ROA
- MIA
1 stop5h 17m
Delta
Sat 5/236:00 am
MIA
- ROA
1 stop4h 30m
Delta
Deal found 4/10![Delta logo]()
$322
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:58 pm
ROA
- MIA
1 stop4h 49m
American Airlines
Sat 5/306:20 am
MIA
- ROA
1 stop4h 25m
American Airlines
Deal found 4/8![American Airlines logo]()
$280
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/234:29 pm
ROA
- MIA
1 stop5h 28m
American Airlines
Tue 5/266:20 am
MIA
- ROA
1 stop4h 25m
American Airlines
Deal found 4/6![American Airlines logo]()
$347
One-way flights from Roanoke to Florida KeysSearch for one-way flight options from Roanoke to Florida Keys. Find affordable one-way fares based on user searches. Data last updated April 11, 2026.
Search for one-way flight options from Roanoke to Florida Keys. Find affordable one-way fares based on user searches. Data last updated April 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/183:09 pm
ROA
- MIA
2 stops22h 11m
Multiple Airlines
Deal found 4/10![Multiple Airlines logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/249:23 pm
ROA
- EYW
1 stop18h 23m
Allegiant Air
Deal found 4/6![Allegiant Air logo]()
$185
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/197:28 am
ROA
- MIA
1 stop11h 14m
American Airlines
Deal found 4/10![American Airlines logo]()
$264
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3010:34 am
ROA
- MIA
1 stop5h 42m
United Airlines
Deal found 4/9![United Airlines logo]()
$279
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:45 am
ROA
- MIA
1 stop15h 48m
United Airlines
Deal found 4/6![United Airlines logo]()
$299
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/245:00 am
ROA
- EYW
2 stops8h 07m
American Airlines
Deal found 4/6![American Airlines logo]()
$333
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/303:53 pm
ROA
- MIA
3 stops32h 56m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$420
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:15 am
ROA
- MIA
1 stop5h 20m
United Airlines
Deal found 4/9![United Airlines logo]()
$471
Find flight deals from Roanoke to Florida Keys
Keep the following information in mind while searching for Roanoke to Florida Keys flight deals. Data was last updated April 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $280 (American Airlines) |
One-way from | $140 (Kiwi.com) |
Popular in | March |
Cheapest in | November |
Average price | $489 |
Cheapflights Fare Finder
Customize your flight search to find flights from Roanoke to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 11, 2026.
Use the filters below to find and compare flights from Roanoke to Florida Keys that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RoanokeMiami
ROA - MIA
ROAMIA
Roanoke
Mon 5/18
7:30 pm-12:47 am
1 stop5h 17m
Miami
Sat 5/23
9:00 am-5:20 pm
1 stop8h 20m
$322
RoanokeMiami
ROA - MIA
ROAMIA
Roanoke
Thu 5/7
6:00 am-12:56 pm
1 stop6h 56m
Miami
Sat 5/9
6:00 am-10:30 am
1 stop4h 30m
$322
RoanokeKey West
ROA - EYW
ROAEYW
Roanoke
Tue 5/12
7:05 am-1:42 pm
1 stop6h 37m
Key West
Tue 5/19
2:32 pm-11:00 pm
1 stop8h 28m
$323
RoanokeKey West
ROA - EYW
ROAEYW
Roanoke
Sat 7/25
8:10 am-6:47 pm
2 stops10h 37m
Key West
Wed 7/29
7:29 pm-11:55 pm
1 stop4h 26m
$328
RoanokeMiami
ROA - MIA
ROAMIA
Roanoke
Tue 4/21
8:37 am-3:05 pm
1 stop6h 28m
Miami
Sat 4/25
8:55 am-5:02 pm
1 stop8h 07m
$339
RoanokeMiami
ROA - MIA
ROAMIA
Roanoke
Thu 5/7
6:00 am-12:56 pm
1 stop6h 56m
Miami
Mon 5/18
7:39 pm-12:34 am
1 stop4h 55m
$363
RoanokeMiami
ROA - MIA
ROAMIA
Roanoke
Wed 7/22
7:57 pm-12:55 am
1 stop4h 58m
Miami
Sat 7/25
6:00 pm-11:50 pm
1 stop5h 50m
$367
RoanokeMiami
ROA - MIA
ROAMIA
Roanoke
Wed 7/22
7:05 am-12:55 am
2 stops17h 50m
Miami
Tue 7/28
7:16 pm-11:50 pm
1 stop4h 34m
$389
RoanokeKey West
ROA - EYW
ROAEYW
Roanoke
Tue 5/26
8:10 am-6:49 pm
2 stops10h 39m
Key West
Tue 6/2
7:29 pm-11:47 pm
1 stop4h 18m
$391
RoanokeKey West
ROA - EYW
ROAEYW
Roanoke
Tue 5/26
6:00 am-10:53 am
1 stop4h 53m
Key West
Tue 6/2
6:19 pm-12:34 am
1 stop6h 15m
$411
Showing 1-10 of 29 resultsSorted by cheapest first
Best time to book a flight from Roanoke to Florida Keys
Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Roanoke with our price prediction graph.
ROA-MIA
ROA-EYW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Roanoke to Florida Keys
ROA-zzEOA
ROA-MIA
ROA-EYW
What is the cheapest month to book a flight from Roanoke to Florida Keys?
Currently, February is the cheapest month in which you can book a flight from Roanoke to Florida Keys (average of $233). Flying from Roanoke to Florida Keys in November is currently the most expensive (average of $413). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Florida Keys
Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated April 11, 2026.
Read through reviews of airlines operating flights from Roanoke to Florida Keys, such as Delta and American Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Entertainment
7.8
Boarding
8.1
Food
7.2
Comfort
7.9
Crew
8.5
Reviews
1 / 20
2.0
MediocreJoseph,Aug 2023
MSP - MCO
Overall
7.9
Entertainment
7.8
Boarding
8.1
Food
7.2
Comfort
7.9
Crew
8.5
Reviews
1 / 20
2.0
MediocreJoseph,Aug 2023
MSP - MCO
Overall
7.9
Entertainment
7.8
Boarding
8.1
Food
7.2
Comfort
7.9
Crew
8.5
Reviews
1 / 20
2.0
MediocreJoseph,Aug 2023
MSP - MCO
Related info for your journey
Find useful and relevant information for your journey from Roanoke to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Roanoke and Florida Keys flights
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Consider these flights traveling from Roanoke to Florida Keys.
Top 2 airlines flying from Roanoke to Florida Keys
Discover the top 2 airlines that operate flights from Roanoke to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$465 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$248 | Average$473 | FlexibilityNo cancel fee | On-timeN/A |