$168+ Cheap flights from Panama City, FL (ECP) to Florida Keys
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/2. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — EYW
Apr 9 — Apr 161
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to Florida Keys with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to Florida Keys
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Cheapest flights from Panama City to Florida KeysExplore the most affordable flight options available from Panama City to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.
Explore the most affordable flight options available from Panama City to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:29 pm
ECP
- MIA
1 stop4h 22m
Delta
Wed 5/277:39 pm
MIA
- ECP
1 stop4h 22m
Delta
Deal found 3/5![Delta logo]()
$335
This Delta deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/301:30 pm
ECP
- EYW
1 stop5h 11m
Delta
Tue 4/76:25 pm
EYW
- ECP
1 stop5h 39m
Delta
Deal found 3/7![Delta logo]()
$347
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:49 am
ECP
- MIA
1 stop5h 22m
Delta
Tue 4/217:04 am
MIA
- ECP
1 stop4h 11m
Delta
Deal found 3/9![Delta logo]()
$355
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:05 pm
ECP
- MIA
1 stop4h 47m
Delta
Sat 10/246:40 am
MIA
- ECP
2 stops17h 07m
Delta
Deal found 3/6![Delta logo]()
$360
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/122:37 pm
ECP
- EYW
1 stop6h 10m
American Airlines
Mon 11/164:53 pm
EYW
- ECP
1 stop7h 56m
American Airlines
Deal found 3/6![American Airlines logo]()
$367
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/147:05 pm
ECP
- MIA
1 stop4h 47m
Delta
Mon 10/267:00 am
MIA
- ECP
2 stops13h 36m
Delta
Deal found 3/6![Delta logo]()
$370
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:45 am
ECP
- MIA
1 stop6h 55m
Delta
Mon 10/265:55 pm
MIA
- ECP
1 stop5h 52m
Delta
Deal found 3/6![Delta logo]()
$375
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/184:40 pm
ECP
- MIA
1 stop5h 11m
American Airlines
Sat 4/255:30 pm
MIA
- ECP
1 stop7h 16m
American Airlines
Deal found 3/8![American Airlines logo]()
$376
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:00 am
ECP
- MIA
1 stop4h 00m
Delta
Thu 10/222:03 pm
MIA
- ECP
1 stop6h 33m
Delta
Deal found 3/6![Delta logo]()
$377
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:05 pm
ECP
- MIA
1 stop4h 47m
Delta
Sat 10/246:40 am
MIA
- ECP
2 stops17h 07m
Delta
Deal found 3/6![Delta logo]()
$380
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:05 pm
ECP
- MIA
1 stop4h 47m
Delta
Mon 10/267:00 am
MIA
- ECP
2 stops13h 36m
Delta
Deal found 3/6![Delta logo]()
$390
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:00 am
ECP
- MIA
1 stop10h 18m
Delta
Wed 10/214:40 pm
MIA
- ECP
1 stop3h 56m
Delta
Deal found 3/6![Delta logo]()
$395
Best flights from Panama City to Florida KeysDiscover carefully curated flight deals from Panama City to Florida Keys that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 10, 2026.
Discover carefully curated flight deals from Panama City to Florida Keys that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 10, 2026.
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:29 pm
ECP
- MIA
1 stop4h 22m
Delta
Wed 5/277:39 pm
MIA
- ECP
1 stop4h 22m
Delta
Deal found 3/5![Delta logo]()
$335
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/812:18 pm
ECP
- MIA
1 stop5h 24m
American Airlines
Tue 5/126:37 pm
MIA
- ECP
1 stop5h 15m
American Airlines
Deal found 3/9![American Airlines logo]()
$355
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/137:10 am
ECP
- MIA
2 stops9h 20m
Southwest
Tue 4/2112:10 pm
MIA
- ECP
1 stop7h 45m
Southwest
Deal found 3/9![Southwest logo]()
$436
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:21 am
ECP
- MIA
1 stop4h 51m
Delta
Wed 4/156:15 pm
MIA
- ECP
1 stop5h 57m
Delta
Deal found 3/5![Delta logo]()
$335
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:49 am
ECP
- MIA
1 stop3h 57m
Delta
Tue 4/216:15 pm
MIA
- ECP
1 stop5h 57m
Delta
Deal found 3/9![Delta logo]()
$335
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/254:57 pm
ECP
- EYW
1 stop22h 00m
United Airlines
Wed 4/294:38 pm
EYW
- ECP
1 stop6h 21m
United Airlines
Deal found 3/5![United Airlines logo]()
$768
This Southwest deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/247:40 am
ECP
- MIA
2 stops12h 40m
Southwest
Mon 6/294:00 pm
MIA
- ECP
1 stop5h 10m
Southwest
Deal found 3/5![Southwest logo]()
$436
This Southwest deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:40 am
ECP
- MIA
2 stops10h 45m
Southwest
Sat 5/308:25 am
MIA
- ECP
1 stop10h 25m
Southwest
Deal found 3/5![Southwest logo]()
$442
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2010:48 am
ECP
- EYW
2 stops11h 10m
American Airlines
Wed 5/271:37 pm
EYW
- ECP
2 stops11h 03m
American Airlines
Deal found 3/5![American Airlines logo]()
$508
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/812:20 pm
ECP
- MIA
1 stop5h 05m
Southwest
Tue 5/127:20 am
MIA
- ECP
2 stops12h 35m
Southwest
Deal found 3/9![Southwest logo]()
$447
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/141:50 pm
ECP
- EYW
1 stop4h 59m
Delta
Mon 5/186:19 pm
EYW
- ECP
1 stop6h 09m
Delta
Deal found 3/5![Delta logo]()
$463
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/234:40 pm
ECP
- EYW
1 stop4h 56m
American Airlines
Mon 4/2711:56 am
EYW
- ECP
1 stop5h 07m
American Airlines
Deal found 3/9![American Airlines logo]()
$519
This Southwest deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:15 am
ECP
- MIA
2 stops10h 45m
Southwest
Mon 4/65:10 am
MIA
- ECP
2 stops8h 40m
Southwest
Deal found 3/7![Southwest logo]()
$452
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/21:30 pm
ECP
- EYW
1 stop5h 11m
Delta
Sun 4/56:25 pm
EYW
- ECP
1 stop5h 39m
Delta
Deal found 3/9![Delta logo]()
$575
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/206:00 am
ECP
- EYW
1 stop3h 48m
Delta
Tue 3/242:40 pm
EYW
- ECP
1 stop6h 07m
Delta
Deal found 3/5![Delta logo]()
$699
Last-minute flights from Panama City to Florida KeysDiscover last-minute flight deals from Panama City to Florida Keys. Data last updated March 10, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Florida Keys. Data last updated March 10, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/301:30 pm
ECP
- EYW
1 stop5h 11m
Delta
Tue 4/76:25 pm
EYW
- ECP
1 stop5h 39m
Delta
Deal found 3/7![Delta logo]()
$347
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:49 am
ECP
- MIA
1 stop5h 22m
Delta
Tue 4/217:04 am
MIA
- ECP
1 stop4h 11m
Delta
Deal found 3/9![Delta logo]()
$355
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:49 am
ECP
- MIA
1 stop3h 57m
Delta
Mon 4/206:15 pm
MIA
- ECP
1 stop4h 07m
Delta
Deal found 3/9![Delta logo]()
$375
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/137:10 am
ECP
- MIA
2 stops9h 20m
Southwest
Tue 4/2112:10 pm
MIA
- ECP
1 stop7h 45m
Southwest
Deal found 3/9![Southwest logo]()
$436
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:21 am
ECP
- MIA
1 stop6h 14m
Delta
Tue 4/216:00 am
MIA
- ECP
1 stop5h 15m
Delta
Deal found 3/9![Delta logo]()
$335
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/151:33 pm
ECP
- MIA
1 stop4h 02m
Delta
Wed 4/226:00 am
MIA
- ECP
1 stop5h 15m
Delta
Deal found 3/9![Delta logo]()
$427
This Southwest deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/179:55 am
ECP
- MIA
1 stop4h 25m
Southwest
Sun 4/196:10 am
MIA
- ECP
2 stops8h 05m
Southwest
Deal found 3/7![Southwest logo]()
$447
This American Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1712:18 pm
ECP
- MIA
1 stop7h 29m
American Airlines
Sun 4/196:54 am
MIA
- ECP
1 stop5h 54m
American Airlines
Deal found 3/7![American Airlines logo]()
$451
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/184:40 pm
ECP
- MIA
1 stop5h 11m
American Airlines
Sat 4/255:30 pm
MIA
- ECP
1 stop7h 16m
American Airlines
Deal found 3/8![American Airlines logo]()
$376
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/185:10 pm
ECP
- MIA
1 stop6h 44m
Delta
Thu 4/236:15 pm
MIA
- ECP
1 stop5h 57m
Delta
Deal found 3/9![Delta logo]()
$397
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1811:05 am
ECP
- MIA
1 stop4h 55m
Southwest
Sat 4/259:30 am
MIA
- ECP
1 stop7h 15m
Southwest
Deal found 3/8![Southwest logo]()
$431
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/247:10 am
ECP
- MIA
2 stops9h 20m
Southwest
Sun 4/267:00 am
MIA
- ECP
1 stop9h 30m
Southwest
Deal found 3/6![Southwest logo]()
$442
One-way flights from Panama City to Florida KeysSearch for one-way flight options from Panama City to Florida Keys. Find affordable one-way fares based on user searches. Data last updated March 10, 2026.
Search for one-way flight options from Panama City to Florida Keys. Find affordable one-way fares based on user searches. Data last updated March 10, 2026.
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/21:50 pm
ECP
- MIA
1 stop6h 28m
Delta
Deal found 3/9![Delta logo]()
$168
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/14:31 pm
ECP
- MIA
1 stop5h 17m
Delta
Deal found 3/8![Delta logo]()
$188
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/214:16 pm
ECP
- MIA
1 stop4h 44m
American Airlines
Deal found 3/6![American Airlines logo]()
$208
This Delta deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:43 pm
ECP
- MIA
1 stop5h 09m
Delta
Deal found 3/7![Delta logo]()
$210
This deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/63:00 pm
ECP
- MIA
1 stop3h 58m
Delta
Deal found 3/5![Delta logo]()
$220
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:40 am
ECP
- MIA
2 stops10h 45m
Southwest
Deal found 3/6![Southwest logo]()
$221
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:00 am
ECP
- MIA
1 stop5h 09m
Delta
Deal found 3/9![Delta logo]()
$227
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:15 am
ECP
- MIA
1 stop9h 00m
Southwest
Deal found 3/9![Southwest logo]()
$232
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/286:45 pm
ECP
- MIA
1 stop5h 02m
American Airlines
Deal found 3/9![American Airlines logo]()
$234
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/224:23 pm
ECP
- MIA
1 stop5h 04m
Delta
Deal found 3/6![Delta logo]()
$249
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/285:40 am
ECP
- MIA
2 stops7h 50m
Southwest
Deal found 3/9![Southwest logo]()
$254
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/211:30 pm
ECP
- MIA
1 stop6h 20m
Delta
Deal found 3/5![Delta logo]()
$259
Find flight deals from Panama City to Florida Keys
Keep the following information in mind while searching for Panama City to Florida Keys flight deals. Data was last updated March 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $335 (Delta) |
One-way from | $168 (Delta) |
Popular in | March |
Cheapest in | August |
Average price | $632 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
Use the filters below to find and compare flights from Panama City to Florida Keys that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Panama CityMiami
ECP - MIA
ECPMIA
Panama City NW Florida Beaches
Wed 5/20
5:29 pm-10:51 pm
1 stop4h 22m
Miami
Wed 5/27
7:39 pm-11:01 pm
1 stop4h 22m
$335
Panama CityMiami
ECP - MIA
ECPMIA
Panama City NW Florida Beaches
Wed 4/15
8:21 am-2:12 pm
1 stop4h 51m
Miami
Wed 4/15
6:15 pm-11:12 pm
1 stop5h 57m
$335
Panama CityMiami
ECP - MIA
ECPMIA
Panama City NW Florida Beaches
Tue 4/14
5:49 am-10:46 am
1 stop3h 57m
Miami
Tue 4/21
6:15 pm-11:12 pm
1 stop5h 57m
$335
Panama CityMiami
ECP - MIA
ECPMIA
Panama City NW Florida Beaches
Fri 5/8
12:18 pm-6:42 pm
1 stop5h 24m
Miami
Tue 5/12
6:37 pm-10:52 pm
1 stop5h 15m
$355
Panama CityMiami
ECP - MIA
ECPMIA
Panama City NW Florida Beaches
Mon 4/13
7:10 am-5:30 pm
2 stops9h 20m
Miami
Tue 4/21
12:10 pm-6:55 pm
1 stop7h 45m
$436
Panama CityMiami
ECP - MIA
ECPMIA
Panama City NW Florida Beaches
Wed 6/24
7:40 am-9:20 pm
2 stops12h 40m
Miami
Mon 6/29
4:00 pm-8:10 pm
1 stop5h 10m
$436
Panama CityMiami
ECP - MIA
ECPMIA
Panama City NW Florida Beaches
Mon 5/25
6:40 am-6:25 pm
2 stops10h 45m
Miami
Sat 5/30
8:25 am-5:50 pm
1 stop10h 25m
$442
Panama CityMiami
ECP - MIA
ECPMIA
Panama City NW Florida Beaches
Fri 5/8
12:20 pm-6:25 pm
1 stop5h 05m
Miami
Tue 5/12
7:20 am-6:55 pm
2 stops12h 35m
$447
Panama CityMiami
ECP - MIA
ECPMIA
Panama City NW Florida Beaches
Thu 4/2
6:15 am-6:00 pm
2 stops10h 45m
Miami
Mon 4/6
5:10 am-12:50 pm
2 stops8h 40m
$452
Panama CityKey West
ECP - EYW
ECPEYW
Panama City NW Florida Beaches
Thu 5/14
1:50 pm-7:49 pm
1 stop4h 59m
Key West
Mon 5/18
6:19 pm-11:28 pm
1 stop6h 09m
$463
Showing 1-10 of 27 resultsSorted by cheapest first
Best time to book a flight from Panama City to Florida Keys
Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Panama City with our price prediction graph.
ECP-MIA
ECP-EYW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Florida Keys
ECP-zzEOA
ECP-MIA
ECP-EYW
What is the cheapest month to book a flight from Panama City, Florida to Florida Keys?
Currently, September is the cheapest month in which you can book a flight from Panama City, Florida to Florida Keys (average of $161). Flying from Panama City, Florida to Florida Keys in February is currently the most expensive (average of $332). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Florida Keys
Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated March 10, 2026.
See what other customers who have flown with Southwest,Delta, andAmerican Airlines from Panama City to Florida Keys have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
8.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Comfort
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
8.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Comfort
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
8.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Comfort
8.0
Food
7.0
Entertainment
7.5
Boarding
8.1
Crew
8.6
Overall
8.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Related info for your journey
Find useful and relevant information for your journey from Panama City to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Panama City to Florida Keys
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Complete your trip
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Panama City and Florida Keys flights
Browse other Panama City and Florida Keys flight options. Last updated on March 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Panama City to Florida Keys flights
Consider these flights traveling from Panama City to Florida Keys.
Top 2 airlines flying from Panama City to Florida Keys
Discover the top 2 airlines that operate flights from Panama City to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$296 | Average$332 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$306 | Average$483 | FlexibilityNo cancel fee | On-timeN/A |