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Florida Keys

$88+ Cheap flights from Panama City, FL (ECP) to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/23. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — EYW
Aug 21 — Aug 281
Thu 8/21
Thu 8/28
1 adult, Economy
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Cheap flight deals from Panama City to Florida Keys

Keep the following information in mind while searching for Panama City to Florida Keys flight deals. Data was last updated August 16, 2025.

Round-trip from

$175
(Delta)

One-way from

$88
(Delta)

Popular in

December

Cheapest in

August

Average price

$286
From Panama City NW Florida Beaches to Florida Keys
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One-way flight from Panama City NW Florida Beaches to Florida Keys
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Highest demand for flights based on searches. 9% potential increase in price ($44 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Panama City to Florida Keys

Cheapest flights from Panama City to Florida Keys
Explore the most affordable flight options available from Panama City to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 16, 2025.

This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/95:02 pmECP - MIA
1 stop6h 22mDelta
Tue 9/162:45 pmMIA - ECP
1 stop5h 45mDelta
Deal found 8/14$175
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/95:02 pmECP - MIA
1 stop6h 22mDelta
Thu 9/117:38 pmMIA - ECP
1 stop4h 25mDelta
Deal found 8/14$186
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/41:53 pmECP - MIA
1 stop6h 35mDelta
Thu 9/117:38 pmMIA - ECP
1 stop4h 25mDelta
Deal found 8/14$197
This Southwest deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/610:55 amECP - MIA
2 stops9h 30mSouthwest
Sat 9/135:50 amMIA - ECP
1 stop8h 20mSouthwest
Deal found 8/14$202
This Southwest deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/307:20 amECP - MIA
2 stops13h 45mSouthwest
Sat 11/15:45 amMIA - ECP
1 stop6h 00mSouthwest
Deal found 8/13$208
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/55:02 pmECP - MIA
1 stop6h 22mDelta
Tue 9/167:38 pmMIA - ECP
1 stop4h 25mDelta
Deal found 8/14$221
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/511:22 amECP - MIA
1 stop6h 03mDelta
Mon 9/157:38 pmMIA - ECP
1 stop4h 25mDelta
Deal found 8/14$232
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/246:00 amECP - MIA
1 stop4h 01mDelta
Wed 9/244:25 pmMIA - ECP
1 stop4h 05mDelta
Deal found 8/13$236
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/96:00 amECP - MIA
1 stop6h 33mDelta
Wed 9/102:45 pmMIA - ECP
1 stop6h 03mDelta
Deal found 8/14$237
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/47:10 amECP - MIA
1 stop7h 10mDelta
Wed 9/102:45 pmMIA - ECP
1 stop6h 03mDelta
Deal found 8/14$248
This American Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1111:18 amECP - EYW
2 stops6h 20mAmerican Airlines
Tue 12/168:10 amEYW - ECP
1 stop6h 37mAmerican Airlines
Deal found 8/15$302
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/217:10 amECP - EYW
1 stop8h 02mAmerican Airlines
Fri 11/285:26 pmEYW - ECP
1 stop7h 01mAmerican Airlines
Deal found 8/14$307

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 16, 2025.
Use the filters below to find and compare flights from Panama City to Florida Keys that are best for you.

Fly from

Panama City

Fly to

Florida Keys

Route

Depart

Return

Price

Panama CityMiami

ECP - MIA

ECPMIA

Panama City NW Florida Beaches

Tue 9/9

7:10 am-3:20 pm

1 stop7h 10m

Miami

Tue 9/23

10:28 am-1:20 pm

1 stop3h 52m

$175

Panama CityMiami

ECP - MIA

ECPMIA

Panama City NW Florida Beaches

Tue 9/9

5:02 pm-12:24 am

1 stop6h 22m

Miami

Tue 9/16

2:45 pm-7:30 pm

1 stop5h 45m

$175

Panama CityMiami

ECP - MIA

ECPMIA

Panama City NW Florida Beaches

Thu 9/25

2:05 pm-9:23 pm

1 stop6h 18m

Miami

Tue 9/30

4:25 pm-7:30 pm

1 stop4h 05m

$186

Panama CityMiami

ECP - MIA

ECPMIA

Panama City NW Florida Beaches

Tue 9/9

7:10 am-3:20 pm

1 stop7h 10m

Miami

Mon 9/15

7:38 pm-11:03 pm

1 stop4h 25m

$186

Panama CityMiami

ECP - MIA

ECPMIA

Panama City NW Florida Beaches

Mon 9/8

6:00 am-10:52 am

1 stop3h 52m

Miami

Tue 9/16

7:30 am-1:20 pm

1 stop6h 50m

$186

Panama CityMiami

ECP - MIA

ECPMIA

Panama City NW Florida Beaches

Sat 9/6

6:59 pm-12:24 am

1 stop4h 25m

Miami

Tue 9/16

2:45 pm-7:30 pm

1 stop5h 45m

$186

Panama CityMiami

ECP - MIA

ECPMIA

Panama City NW Florida Beaches

Wed 10/1

6:00 am-11:01 am

1 stop4h 01m

Miami

Mon 10/6

7:10 am-12:30 pm

1 stop6h 20m

$186

Panama CityMiami

ECP - MIA

ECPMIA

Panama City NW Florida Beaches

Tue 9/9

5:02 pm-12:24 am

1 stop6h 22m

Miami

Thu 9/11

7:38 pm-11:03 pm

1 stop4h 25m

$186

Panama CityMiami

ECP - MIA

ECPMIA

Panama City NW Florida Beaches

Tue 9/9

7:10 am-1:33 pm

1 stop5h 23m

Miami

Sat 9/13

7:25 pm-11:03 pm

1 stop4h 38m

$186

Panama CityMiami

ECP - MIA

ECPMIA

Panama City NW Florida Beaches

Thu 9/4

11:22 am-6:25 pm

1 stop6h 03m

Miami

Tue 9/16

7:38 pm-11:03 pm

1 stop4h 25m

$186

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/14

Showing 1-10 of 32 results
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Best time to book a flight from Panama City to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Florida Keys

What is the cheapest month to book a flight from Panama City, Florida to Florida Keys?

Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to Florida Keys (average of $328). Flying from Panama City, Florida to Florida Keys in March is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Florida Keys

Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated August 16, 2025.
See what other customers who have flown with Southwest, Delta, and American Airlines from Panama City to Florida Keys have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,246 reviews

Overall

8.0

Crew

8.6

Comfort

8.0

Food

7.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.
Southwest
8.0
Very good
4,246 reviews
Southwest
8.0
Very good
4,246 reviews

Overall

8.0

Crew

8.6

Comfort

8.0

Food

7.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.
Delta
8.0
Very good
7,985 reviews
Southwest
8.0
Very good
4,246 reviews

Overall

8.0

Crew

8.6

Comfort

8.0

Food

7.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,246 reviews

Overall

8.0

Crew

8.6

Comfort

8.0

Food

7.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Florida Keys?

    If you book a flight to Florida Keys from Panama City, you will be flying from NW Florida Beaches, which is the city’s only airport. Panama City NW Florida Beaches (ECP) is located 16.0 mi from the center of Panama City.

  • Can I find deals for flights from Panama City to Florida Keys that include hotel bookings?

    Yes. In addition to deals on Panama City to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Florida Keys.

  • Can I find deals for business class flights from Panama City to Florida Keys?

    Yes. Cheapflights offers flight deals from Panama City to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Florida Keys?

    Currently, August is the cheapest month in which you can book a flight from Panama City, Florida to Florida Keys (average of $328). Flying from Panama City, Florida to Florida Keys in March is currently the most expensive (average of $492). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 2 airlines flying from Panama City to Florida Keys

Discover the top 2 airlines that operate flights from Panama City to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$296Average$468FlexibilityNo cancel feeOn-time71%
DeltaCheapest$322Average$567FlexibilityNo cancel feeOn-timeN/A

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