$193+ Cheap flights from Tampa to Panama City, FL (TPA - ECP)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/10. Fares are subject to change and may not be available on all flights or dates of travel.
TPA — ECP
Oct 28 — Nov 41
Round-trip
1 adult, Economy
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Find cheap flights from Tampa to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Tampa to Panama City
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Cheapest flights from Tampa to Panama CityExplore the most affordable flight options available from Tampa to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 28, 2026.
Explore the most affordable flight options available from Tampa to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 28, 2026.
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/274:38 pm -
1 stop4h 25m
Tue 11/34:15 pm -
1 stop3h 27m
Deal found 9/27![Delta logo]()
$385
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:59 pm -
1 stop4h 19m
Mon 10/266:20 pm -
1 stop4h 58m
Deal found 9/23![Delta logo]()
$425
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:10 am -
1 stop6h 25m
Wed 10/289:19 am -
1 stop6h 19m
Deal found 9/23![Delta logo]()
$445
This Delta deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/133:20 pm -
1 stop3h 45m
Sun 11/156:00 am -
1 stop4h 15m
Deal found 9/25![Delta logo]()
$452
This Delta deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/234:41 pm -
1 stop5h 25m
Fri 10/305:34 pm -
1 stop5h 44m
Deal found 9/25![Delta logo]()
$465
This Southwest deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/41:55 pm -
1 stop7h 40m
Mon 11/95:55 pm -
1 stop4h 40m
Deal found 9/23![Southwest logo]()
$481
This Southwest deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:10 am -
2 stops7h 15m
Mon 10/263:10 pm -
1 stop7h 25m
Deal found 9/23![Southwest logo]()
$486
This Southwest deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2111:25 am -
2 stops8h 00m
Wed 10/288:05 am -
2 stops8h 50m
Deal found 9/23![Southwest logo]()
$502
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:15 am -
1 stop7h 05m
Mon 10/265:40 pm -
1 stop5h 30m
Deal found 9/27![Southwest logo]()
$503
Best flights from Tampa to Panama CityDiscover carefully curated flight deals from Tampa to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 28, 2026.
Discover carefully curated flight deals from Tampa to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 28, 2026.
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/274:38 pm -
1 stop4h 25m
Tue 11/34:15 pm -
1 stop3h 27m
Deal found 9/27![Delta logo]()
$385
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/271:30 pm -
1 stop5h 55m
Tue 11/310:05 am -
2 stops6h 35m
Deal found 9/27![Southwest logo]()
$486
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:59 pm -
1 stop4h 19m
Mon 10/266:20 pm -
1 stop4h 58m
Deal found 9/23![Delta logo]()
$425
This Southwest deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:10 am -
2 stops7h 15m
Mon 10/263:10 pm -
1 stop7h 25m
Deal found 9/23![Southwest logo]()
$486
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/133:20 pm -
1 stop3h 45m
Sun 11/156:00 am -
1 stop4h 15m
Deal found 9/24![Delta logo]()
$452
This Southwest deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2310:10 am -
1 stop5h 20m
Fri 10/304:00 pm -
1 stop6h 15m
Deal found 9/25![Southwest logo]()
$492
This Delta deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/234:41 pm -
1 stop5h 25m
Fri 10/305:34 pm -
1 stop5h 44m
Deal found 9/26![Delta logo]()
$465
This Southwest deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:20 am -
2 stops9h 05m
Sun 11/157:00 am -
2 stops10h 05m
Deal found 9/24![Southwest logo]()
$502
This Southwest deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2111:25 am -
2 stops8h 00m
Wed 10/288:05 am -
2 stops8h 50m
Deal found 9/23![Southwest logo]()
$502
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:15 am -
1 stop7h 05m
Mon 10/265:40 pm -
1 stop5h 30m
Deal found 9/27![Southwest logo]()
$503
Last-minute flights from Tampa to Panama CityDiscover last-minute flight deals from Tampa to Panama City. Data last updated September 28, 2026 and is based on user searches.
Discover last-minute flight deals from Tampa to Panama City. Data last updated September 28, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:10 am -
1 stop6h 25m
Wed 10/289:19 am -
1 stop6h 19m
Deal found 9/23![Delta logo]()
$445
This Southwest deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2111:25 am -
2 stops8h 00m
Wed 10/288:05 am -
2 stops8h 50m
Deal found 9/23![Southwest logo]()
$502
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:59 pm -
1 stop4h 19m
Mon 10/266:20 pm -
1 stop4h 58m
Deal found 9/23![Delta logo]()
$425
This Delta deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/234:41 pm -
1 stop5h 25m
Fri 10/305:34 pm -
1 stop5h 44m
Deal found 9/25![Delta logo]()
$465
This Southwest deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:10 am -
2 stops7h 15m
Mon 10/263:10 pm -
1 stop7h 25m
Deal found 9/23![Southwest logo]()
$486
This Southwest deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:45 am -
2 stops8h 25m
Fri 10/301:50 pm -
1 stop5h 50m
Deal found 9/25![Southwest logo]()
$497
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:15 am -
1 stop7h 05m
Mon 10/265:40 pm -
1 stop5h 30m
Deal found 9/27![Southwest logo]()
$503
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/274:38 pm -
1 stop4h 25m
Tue 11/34:15 pm -
1 stop3h 27m
Deal found 9/27![Delta logo]()
$385
One-way flights from Tampa to Panama CitySearch for one-way flight options from Tampa to Panama City. Find affordable one-way fares based on user searches. Data last updated September 28, 2026.
Search for one-way flight options from Tampa to Panama City. Find affordable one-way fares based on user searches. Data last updated September 28, 2026.
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1011:20 am -
1 stop4h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Delta logo]()
$193
This Delta deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:10 am -
1 stop4h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Delta logo]()
$213
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/512:40 pm -
2 stops8h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Southwest logo]()
$246
This Southwest deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2012:45 pm -
1 stop4h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Southwest logo]()
$252
This Delta deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/158:59 pm -
2 stops12h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![Delta logo]()
$298
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:50 am -
1 stop7h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Southwest logo]()
$385
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/204:00 pm -
3 stops22h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![United Airlines logo]()
$475
This Southwest deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/99:10 am -
2 stops7h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![Southwest logo]()
$530
This United Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/99:15 am -
3 stops13h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![United Airlines logo]()
$618
This United Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/89:00 am -
3 stops30h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/27![United Airlines logo]()
$686
Find flight deals from Tampa to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Tampa (TPA) to Panama City (ECP). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 28, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $385 (Delta) |
One-way from | $213 (Delta) |
Popular in | May |
Cheapest in | December |
Average price | $502 |
Cheapflights Fare Finder
Customize your flight search to find flights from Tampa to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 28, 2026.
Use the filters below to find and compare flights from Tampa to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
TampaPanama City
TPA Tampa - ECP Panama City NW Florida Beaches
TPAECP
Tampa
Tue 11/10
11:20 am-3:06 pm
1 stop4h 46m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$193
Quickest round-trip
TampaPanama City
TPA Tampa - ECP Panama City NW Florida Beaches
TPAECP
Tampa
Thu 11/5
5:10 am-8:14 am
1 stop4h 04m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$213
TampaPanama City
TPA Tampa - ECP Panama City NW Florida Beaches
TPAECP
Tampa
Sun 11/15
6:20 am-10:30 am
1 stop5h 10m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$213
TampaPanama City
TPA Tampa - ECP Panama City NW Florida Beaches
TPAECP
Tampa
Thu 11/5
12:40 pm-8:35 pm
2 stops8h 55m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$246
TampaPanama City
TPA Tampa - ECP Panama City NW Florida Beaches
TPAECP
Tampa
Tue 10/20
12:45 pm-4:30 pm
1 stop4h 45m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$252
TampaPanama City
TPA Tampa - ECP Panama City NW Florida Beaches
TPAECP
Tampa
Fri 10/23
12:30 pm-8:55 pm
2 stops9h 25m
Panama City NW Florida Beaches
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$257
TampaPanama City
TPA Tampa - ECP Panama City NW Florida Beaches
TPAECP
Tampa
Tue 10/27
4:38 pm-8:03 pm
1 stop4h 25m
Panama City NW Florida Beaches
Tue 11/3
4:15 pm-8:42 pm
1 stop3h 27m
$385
TampaPanama City
TPA Tampa - ECP Panama City NW Florida Beaches
TPAECP
Tampa
Fri 10/23
7:59 pm-11:18 pm
1 stop4h 19m
Panama City NW Florida Beaches
Mon 10/26
6:20 pm-12:18 am
1 stop4h 58m
$425
TampaPanama City
TPA Tampa - ECP Panama City NW Florida Beaches
TPAECP
Tampa
Fri 11/13
3:20 pm-6:05 pm
1 stop3h 45m
Panama City NW Florida Beaches
Sun 11/15
6:00 am-11:15 am
1 stop4h 15m
$452
TampaPanama City
TPA Tampa - ECP Panama City NW Florida Beaches
TPAECP
Tampa
Fri 10/23
4:41 pm-9:06 pm
1 stop5h 25m
Panama City NW Florida Beaches
Fri 10/30
5:34 pm-12:18 am
1 stop5h 44m
$465
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Tampa to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Tampa to Panama City in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Tampa-Panama City, Florida flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Tampa-Panama City, Florida flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Tampa-Panama City, Florida flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Tampa-Panama City, Florida flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Tampa-Panama City, Florida flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Tampa to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Tampa with our price prediction graph.
TPA-ECP
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Tampa to Panama City
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 28, 2026.
Peruse reviews from past customers who have flown with Southwest and Delta from Tampa to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Comfort
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Comfort
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Related info for your journey
Find useful and relevant information for your journey from Tampa to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Tampa to Panama City
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Complete your trip
Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Tampa to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Tampa and Panama City flights
Browse other Tampa and Panama City flight options. Last updated on September 28, 2026.
Other flights from Tampa
Browse through other flights departing from Tampa. Flights are based on user searches made on Cheapflights and were last updated on September 28, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 28, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Tampa to Panama City
Discover the top 2 airlines that operate flights from Tampa to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$336 | Average$422 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$401 | Average$494 | FlexibilityNo cancel fee | On-time63% |