HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Florida Keys

$269+ Cheap flights from Moline (MLI) to Florida Keys

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/14. Fares are subject to change and may not be available on all flights or dates of travel.
MLI — EYW
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Moline to Florida Keys with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Moline to Florida Keys

Keep the following information in mind while searching for Moline to Florida Keys flight deals. Data was last updated September 17, 2025.

Round-trip from

$269
(American Airlines)

Popular in

March

Cheapest in

August

Average price

$417
From Moline Quad-City to Florida Keys
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($15 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Moline to Florida Keys

Cheapest flights from Moline to Florida Keys
Explore the most affordable flight options available from Moline to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/145:22 pmMLI - MIA
1 stop5h 27mAmerican Airlines
Sat 11/225:36 pmMIA - MLI
1 stop5h 26mAmerican Airlines
Deal found 9/15$269
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/65:26 pmMLI - MIA
1 stop6h 25mAmerican Airlines
Tue 10/146:35 amMIA - MLI
1 stop5h 17mAmerican Airlines
Deal found 9/15$270
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/294:59 pmMLI - MIA
1 stop6h 24mDelta
Wed 10/86:15 pmMIA - MLI
1 stop5h 05mDelta
Deal found 9/15$294
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/298:35 amMLI - MIA
1 stop5h 36mUnited Airlines
Wed 10/81:15 pmMIA - MLI
2 stops10h 28mUnited Airlines
Deal found 9/15$299
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/125:27 pmMLI - MIA
1 stop5h 25mAmerican Airlines
Tue 12/235:30 pmMIA - MLI
1 stop5h 38mAmerican Airlines
Deal found 9/15$321
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/73:37 pmMLI - MIA
1 stop7h 59mAmerican Airlines
Fri 11/145:18 amMIA - MLI
1 stop6h 20mAmerican Airlines
Deal found 9/16$324
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/114:29 pmMLI - MIA
1 stop7h 00mAmerican Airlines
Fri 10/175:16 pmMIA - MLI
2 stops7h 34mAmerican Airlines
Deal found 9/16$330
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/238:19 amMLI - EYW
1 stop8h 27mAmerican Airlines
Tue 9/306:17 pmEYW - MLI
1 stop5h 08mAmerican Airlines
Deal found 9/16$334
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/65:00 pmMLI - MIA
2 stops16h 20mDelta
Tue 10/146:15 pmMIA - MLI
1 stop5h 05mDelta
Deal found 9/15$354
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/166:30 amMLI - MIA
1 stop7h 41mUnited Airlines
Sun 10/1912:27 pmMIA - MLI
1 stop5h 27mUnited Airlines
Deal found 9/15$372
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/187:28 pmMLI - EYW
1 stop21h 45mAllegiant Air
Mon 12/224:56 pmEYW - MLI
1 stop21h 50mAllegiant Air
Deal found 9/16$377
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/265:57 amMLI - MIA
1 stop6h 31mDelta
Mon 9/296:10 pmMIA - MLI
1 stop5h 32mDelta
Deal found 9/16$379

Cheapflights Fare Finder

 
Customize your flight search to find flights from Moline to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Moline to Florida Keys that are best for you.

Fly from

Moline

Fly to

Florida Keys

Route

Depart

Return

Price

MolineMiami

MLI - MIA

MLIMIA

Moline Quad-City

Fri 11/14

5:22 pm-11:49 pm

1 stop5h 27m

Miami

Sat 11/22

5:36 pm-10:02 pm

1 stop5h 26m

$269

MolineMiami

MLI - MIA

MLIMIA

Moline Quad-City

Sat 10/11

4:29 pm-11:32 pm

1 stop6h 03m

Miami

Fri 10/17

5:15 am-10:14 am

1 stop5h 59m

$269

MolineKey West

MLI - EYW

MLIEYW

Moline Quad-City

Tue 2/24

7:00 am-1:05 pm

1 stop5h 05m

Key West

Wed 3/11

3:08 pm-9:39 pm

1 stop7h 31m

$269

MolineKey West

MLI - EYW

MLIEYW

Moline Quad-City

Wed 1/7

6:41 am-4:03 pm

1 stop8h 22m

Key West

Tue 1/13

4:00 pm-9:28 pm

1 stop6h 28m

$269

MolineKey West

MLI - EYW

MLIEYW

Moline Quad-City

Wed 1/21

6:13 am-3:29 pm

1 stop8h 16m

Key West

Thu 2/5

4:00 pm-9:28 pm

1 stop6h 28m

$269

MolineMiami

MLI - MIA

MLIMIA

Moline Quad-City

Mon 9/29

4:59 pm-12:23 am

1 stop6h 24m

Miami

Wed 10/8

6:15 pm-10:20 pm

1 stop5h 05m

$294

MolineMiami

MLI - MIA

MLIMIA

Moline Quad-City

Mon 10/6

5:00 pm-10:20 am

2 stops16h 20m

Miami

Tue 10/14

6:15 pm-10:20 pm

1 stop5h 05m

$354

MolineMiami

MLI - MIA

MLIMIA

Moline Quad-City

Mon 9/29

8:35 am-10:45 pm

2 stops13h 10m

Miami

Wed 10/8

1:15 pm-10:43 pm

2 stops10h 28m

$360

MolineMiami

MLI - MIA

MLIMIA

Moline Quad-City

Thu 10/16

6:30 am-3:11 pm

1 stop7h 41m

Miami

Sun 10/19

12:27 pm-4:54 pm

1 stop5h 27m

$372

MolineKey West

MLI - EYW

MLIEYW

Moline Quad-City

Thu 12/18

7:28 pm-6:13 pm

1 stop21h 45m

Key West

Mon 12/22

4:56 pm-1:46 pm

1 stop21h 50m

$377

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 18 results
1
2

Best time to book a flight from Moline to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Moline with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Moline to Florida Keys

What is the cheapest month to book a flight from Moline to Florida Keys?

Currently, August is the cheapest month in which you can book a flight from Moline to Florida Keys (average of $328). Flying from Moline to Florida Keys in March is currently the most expensive (average of $491). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Florida Keys

Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated September 17, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Moline to Florida Keys. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
Delta
8.0
Very good
7,961 reviews
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
United Airlines
7.4
Good
8,926 reviews
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Entertainment

7.9

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Joseph,Aug 2023

MSP - MCO

Even if you have delta comfort plus, they will move your overhead bag. One of the perks for upgrading is that you have dedicated space for your carry on with comfort plus with delta. They moved my carry on luggage (3) compartments back and put in bags for other passengers that should have gone under their respective seats. When deboarding the plane, there was no help from anyone to retrieve my luggage back several rows. Delta is turning into pure garbage.

Related info for your journey

Find useful and relevant information for your journey from Moline to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Moline to Florida Keys?

    Most people fly from Moline Quad-City (MLI) if they book a flight from Moline to Florida Keys. Moline Quad-City is conveniently located just 4.0 mi from Moline’s city center.

  • How long is the flight from Moline to Florida Keys?

    Airlines like American Airlines and Delta fly from Moline to Florida Keys in about 5h 27m. The time it takes to get you to your destination can typically vary by up to 57m. Airlines will cover a distance of 1228 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Moline to Florida Keys one-way?

    $272 is the cheapest one-way deal found within the past few days, from Delta. You may also be able to find cheap deals on American Airlines and United Airlines, with prices starting from $300 and $385, respectively.

  • Can I find deals for flights from Moline to Florida Keys that include hotel bookings?

    Yes. In addition to deals on Moline to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Moline to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Moline to Florida Keys.

  • Can I find deals for business class flights from Moline to Florida Keys?

    Yes. Cheapflights offers flight deals from Moline to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Moline to Florida Keys?

    Currently, August is the cheapest month in which you can book a flight from Moline to Florida Keys (average of $328). Flying from Moline to Florida Keys in March is currently the most expensive (average of $491). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Moline to Florida Keys

See prices for flight routes from nearby airports that may be better suited for you.
O'Hare Intl to Orlando flights
O'Hare Intl to Miami flights
O'Hare Intl to Fort Lauderdale flights
O'Hare Intl to Tampa flights
O'Hare Intl to Fort Myers flights
Midway to Orlando flights
Midway to Miami flights
Midway to Tampa flights
Midway to Fort Lauderdale flights
O'Hare Intl to Sarasota flights
St. Louis to Orlando flights
O'Hare Intl to Jacksonville flights
O'Hare Intl to West Palm Beach flights
O'Hare Intl to Key West flights
St. Louis to Miami flights
Midway to Fort Myers flights
O'Hare Intl to Pensacola flights
Midway to West Palm Beach flights
O'Hare Intl to Panama City flights
St. Louis to Tampa flights
Midway to Sarasota flights
Midway to Jacksonville flights
St. Louis to Fort Lauderdale flights
St. Louis to Fort Myers flights
Moline to Orlando flights
St. Louis to Jacksonville flights
Midway to Key West flights
St. Louis to Key West flights
Peoria to Orlando flights
Midway to Panama City flights
St. Louis to Sarasota flights
Midway to Pensacola flights
Moline to Tampa flights
Rockford to Orlando Sanford Intl flights
St. Louis to West Palm Beach flights
O'Hare Intl to Daytona Beach flights
Rockford to St Petersburg flights
St. Louis to Panama City flights
O'Hare Intl to Tallahassee flights
Peoria to Fort Myers flights
O'Hare Intl to Melbourne flights
Bloomington to Orlando flights
Moline to Miami flights
Peoria to Tampa flights
O'Hare Intl to Valparaiso flights
St. Louis to Pensacola flights
Midway to Daytona Beach flights
Moline to Pensacola flights
O'Hare Intl to Gainesville flights
Peoria to Fort Lauderdale flights

Top 3 airlines flying from Moline to Florida Keys

Discover the top 3 airlines that operate flights from Moline to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$268Average$421FlexibilityNo cancel feeOn-time71%
DeltaCheapest$268Average$454FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$395Average$575FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.