HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Florida Keys

$54+ Cheap flights from Charleston (CHS) to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/22. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — EYW
Jan 30 — Feb 61
Fri 1/30
Fri 2/6
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Charleston to Florida Keys with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Charleston to Florida Keys

Cheapest flights from Charleston to Florida Keys
Explore the most affordable flight options available from Charleston to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 31, 2025.

This American Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:07 pmCHS - MIA
Nonstop1h 53mAmerican Airlines
Thu 1/17:00 amMIA - CHS
Nonstop1h 47mAmerican Airlines
Deal found 12/29$247
This Kiwi.com deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:09 pmCHS - EYW
1 stop13h 10mBreeze Airways
Sun 1/48:55 amEYW - CHS
1 stop24h 02mBreeze Airways
Deal found 12/30$322
This Delta deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/314:04 pmCHS - MIA
1 stop6h 04mDelta
Tue 1/67:15 amMIA - CHS
1 stop4h 33mDelta
Deal found 12/28$329
This American Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:30 amCHS - MIA
Nonstop1h 49mAmerican Airlines
Tue 1/610:08 pmMIA - CHS
Nonstop1h 50mAmerican Airlines
Deal found 12/29$371
This American Airlines deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:30 amCHS - MIA
Nonstop1h 49mAmerican Airlines
Sun 1/410:56 pmMIA - CHS
Nonstop1h 49mAmerican Airlines
Deal found 12/28$374
This Southwest deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:00 amCHS - MIA
2 stops10h 10mSouthwest
Thu 1/17:10 amMIA - CHS
1 stop9h 55mSouthwest
Deal found 12/29$386
This Kiwi.com deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/307:05 amCHS - MIA
1 stop29h 33mMultiple Airlines
Tue 1/67:09 pmMIA - CHS
2 stops46h 27mMultiple Airlines
Deal found 12/28$387
This Delta deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:30 amCHS - MIA
1 stop4h 53mDelta
Tue 1/67:15 amMIA - CHS
1 stop4h 33mDelta
Deal found 12/28$391
This Kiwi.com deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:08 pmCHS - EYW
2 stops37h 23mMultiple Airlines
Sun 1/412:20 pmEYW - CHS
1 stop9h 03mMultiple Airlines
Deal found 12/30$433
This Breeze Airways deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/309:08 pmCHS - EYW
1 stop9h 59mBreeze Airways
Sun 1/48:55 amEYW - CHS
1 stop24h 02mBreeze Airways
Deal found 12/29$435
This American Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:10 amCHS - EYW
2 stops8h 03mAmerican Airlines
Sun 1/48:09 pmEYW - CHS
1 stop4h 36mAmerican Airlines
Deal found 12/29$748
This American Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:27 pmCHS - EYW
1 stop4h 17mAmerican Airlines
Sun 1/48:09 pmEYW - CHS
1 stop4h 36mAmerican Airlines
Deal found 12/30$1,292

Find flight deals from Charleston to Florida Keys

Keep the following information in mind while searching for Charleston to Florida Keys flight deals. Data was last updated December 31, 2025.

Most accurate provider

CheapOair
3 stars

Most trusted provider

CheapOair
3 stars

Round-trip from

$142
(Kiwi.com)

One-way from

$54
(American Airlines)

Popular in

December

Cheapest in

August

Average price

$349
Provider with most accurate pricing for Charleston-Miami flight deals.
Search Deals
Provider most trusted by Cheapflights users for Charleston-Miami flights.
Search Deals
From Charleston to Florida Keys
Search Deals
One-way flight from Charleston to Florida Keys
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($8 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 31, 2025.
Use the filters below to find and compare flights from Charleston to Florida Keys that are best for you.

Fly from

Charleston

Fly to

Florida Keys

Route

Depart

Return

Price

CharlestonKey West

CHS - EYW

CHSEYW

Charleston

Thu 2/5

8:59 pm-9:09 am

1 stop12h 10m

Key West

Mon 2/9

1:06 pm-8:38 am

1 stop19h 32m

$151

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Thu 1/22

7:55 am-4:10 pm

1 stop8h 15m

Miami

Tue 1/27

12:55 pm-8:00 pm

1 stop7h 05m

$151

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Mon 2/23

11:06 am-12:56 pm

Nonstop1h 50m

Miami

Tue 3/3

10:00 pm-11:59 pm

Nonstop1h 59m

$155

CharlestonKey West

CHS - EYW

CHSEYW

Charleston

Fri 2/6

6:53 pm-10:09 am

1 stop15h 16m

Key West

Mon 2/9

1:06 pm-8:38 am

1 stop19h 32m

$155

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Thu 1/22

9:05 am-6:35 pm

1 stop9h 30m

Miami

Mon 1/26

7:15 am-3:50 pm

1 stop8h 35m

$156

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Tue 1/27

8:00 am-12:14 pm

1 stop4h 14m

Miami

Tue 2/3

7:15 am-11:48 am

1 stop4h 33m

$157

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Sat 2/14

8:13 pm-10:05 pm

Nonstop1h 52m

Miami

Mon 3/9

10:00 pm-11:59 pm

Nonstop1h 59m

$157

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Sun 2/1

7:00 pm-12:51 am

1 stop5h 51m

Miami

Wed 2/4

1:21 pm-7:18 pm

1 stop5h 57m

$177

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Fri 1/30

7:00 pm-12:51 am

1 stop5h 51m

Miami

Sat 1/31

7:15 am-12:05 pm

1 stop4h 50m

$177

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Thu 2/5

3:28 pm-8:44 pm

1 stop5h 16m

Miami

Fri 2/6

3:25 pm-10:07 pm

1 stop6h 42m

$177

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/30

Showing 1-10 of 41 results
1
2
3
...
5

Best time to book a flight from Charleston to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Florida Keys

What is the cheapest month to book a flight from Charleston to Florida Keys?

Currently, February is the cheapest month in which you can book a flight from Charleston to Florida Keys (average of $64). Flying from Charleston to Florida Keys in April is currently the most expensive (average of $269). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Florida Keys

Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated December 31, 2025.
Read reviews from past customers who have flown Southwest, Delta, and American Airlines from Charleston to Florida Keys. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,251 reviews

Comfort

8.0

Food

7.0

Boarding

8.1

Entertainment

7.5

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,251 reviews
Southwest
8.0
Very good
4,251 reviews

Comfort

8.0

Food

7.0

Boarding

8.1

Entertainment

7.5

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,016 reviews
Southwest
8.0
Very good
4,251 reviews

Comfort

8.0

Food

7.0

Boarding

8.1

Entertainment

7.5

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,074 reviews
Southwest
8.0
Very good
4,251 reviews

Comfort

8.0

Food

7.0

Boarding

8.1

Entertainment

7.5

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
JetBlue
7.2
Good
2,903 reviews
Southwest
8.0
Very good
4,251 reviews

Comfort

8.0

Food

7.0

Boarding

8.1

Entertainment

7.5

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Spirit Airlines
6.3
Okay
8,238 reviews
Southwest
8.0
Very good
4,251 reviews

Comfort

8.0

Food

7.0

Boarding

8.1

Entertainment

7.5

Overall

8.0

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Charleston to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Charleston to Florida Keys?

    Charleston (CHS) is the airport you will fly out of if you book a flight from Charleston to Florida Keys. It is only a 10.2 mi journey to Charleston (CHS) from Charleston’s city center.

  • How long is the flight from Charleston to Florida Keys?

    There are many flights that can get you from Charleston to Florida Keys in 1h 50m. Fly via Breeze Airways, Southwest, or American Airlines to get the fastest option. The distance from Charleston to Florida Keys is about 490 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Charleston to Florida Keys one-way?

    The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $39. However, be on the lookout for offers from Southwest and American Airlines, as they are both options that can get you from Charleston to Florida Keys for a low price.

  • Can I find deals for flights from Charleston to Florida Keys that include hotel bookings?

    Yes. In addition to deals on Charleston to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Florida Keys.

  • Can I find deals for business class flights from Charleston to Florida Keys?

    Yes. Cheapflights offers flight deals from Charleston to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Florida Keys?

    Currently, February is the cheapest month in which you can book a flight from Charleston to Florida Keys (average of $64). Flying from Charleston to Florida Keys in April is currently the most expensive (average of $269). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Charleston to Florida Keys

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to Miami flights
Charlotte to Fort Lauderdale flights
Charlotte to Orlando flights
Charlotte to Tampa flights
Charleston to Fort Lauderdale flights
Charlotte to Sarasota flights
Charlotte to West Palm Beach flights
Charleston to Miami flights
Charlotte to Fort Myers flights
Greenville to Miami flights
Columbia to Orlando flights
Savannah to Miami flights
Charleston to West Palm Beach flights
Charlotte to Key West flights
Myrtle Beach to Fort Lauderdale flights
Charlotte to Jacksonville flights
Columbia to Miami flights
Myrtle Beach to Miami flights
Charleston to Fort Myers flights
Charleston to Tampa flights
Greenville to Orlando flights
Charlotte to Panama City flights
Charlotte to Pensacola flights
Charleston to Orlando flights
Charleston to Key West flights
Greenville to Fort Lauderdale flights
Myrtle Beach to Orlando flights
Savannah to Tampa flights
Greenville to West Palm Beach flights
Myrtle Beach to Tampa flights
Columbia to Tampa flights
Charlotte to Melbourne flights
Columbia to Fort Lauderdale flights
Greenville to Key West flights
Savannah to Fort Lauderdale flights
Greenville to Tampa flights
Savannah to Key West flights
Myrtle Beach to West Palm Beach flights
Myrtle Beach to Fort Myers flights
Savannah to Pensacola flights
Columbia to West Palm Beach flights
Savannah to Orlando flights
Savannah to Fort Myers flights
Augusta to Miami flights
Greenville to Jacksonville flights
Greenville to Sarasota flights
Myrtle Beach to Key West flights
Greenville to Fort Myers flights
Charlotte to Valparaiso flights
Augusta to Orlando flights

Top 3 airlines flying from Charleston to Florida Keys

Discover the top 3 airlines that operate flights from Charleston to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$110Average$220FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$286Average$503FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$326Average$500FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.