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Florida Keys

$59+ Cheap flights from Charleston (CHS) to Florida Keys

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/6. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — EYW
Oct 24 — Oct 311
Fri 10/24
Fri 10/31
1 adult, Economy
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Cheap flight deals from Charleston to Florida Keys

Keep the following information in mind while searching for Charleston to Florida Keys flight deals. Data was last updated September 24, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$117
(American Airlines)

One-way from

$59
(American Airlines)

Popular in

December

Cheapest in

August

Average price

$269
Provider with most accurate pricing for Charleston-Miami flight deals.
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Provider most trusted by Cheapflights users for Charleston-Miami flights.
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From Charleston to Florida Keys
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One-way flight from Charleston to Florida Keys
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Highest demand for flights based on searches. 2% potential increase in price ($8 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Charleston to Florida Keys

Cheapest flights from Charleston to Florida Keys
Explore the most affordable flight options available from Charleston to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 24, 2025.

This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/117:44 pmCHS - MIA
Nonstop1h 42mAmerican Airlines
Sat 10/188:08 amMIA - CHS
Nonstop1h 44mAmerican Airlines
Deal found 9/24$117
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/167:44 pmCHS - MIA
Nonstop1h 42mAmerican Airlines
Mon 10/207:18 amMIA - CHS
Nonstop1h 43mAmerican Airlines
Deal found 9/23$118
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/247:56 pmCHS - MIA
Nonstop1h 42mAmerican Airlines
Thu 11/278:00 pmMIA - CHS
Nonstop1h 51mAmerican Airlines
Deal found 9/24$120
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/96:00 amCHS - MIA
Nonstop1h 38mAmerican Airlines
Thu 11/207:01 amMIA - CHS
Nonstop1h 42mAmerican Airlines
Deal found 9/24$122
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/136:00 amCHS - MIA
Nonstop1h 44mAmerican Airlines
Thu 12/1810:56 pmMIA - CHS
Nonstop1h 49mAmerican Airlines
Deal found 9/24$142
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/86:00 amCHS - MIA
Nonstop1h 38mAmerican Airlines
Sat 11/157:00 amMIA - CHS
Nonstop1h 42mAmerican Airlines
Deal found 9/24$148
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/89:00 amCHS - MIA
1 stop6h 50mDelta
Thu 12/118:05 amMIA - CHS
1 stop5h 19mDelta
Deal found 9/23$167
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/147:56 pmCHS - MIA
Nonstop1h 42mAmerican Airlines
Sun 11/167:00 amMIA - CHS
Nonstop1h 42mAmerican Airlines
Deal found 9/24$173
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/319:10 pmCHS - MIA
1 stop12h 01mMultiple Airlines
Sun 11/210:15 pmMIA - CHS
1 stop19h 58mMultiple Airlines
Deal found 9/24$174
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/178:03 pmCHS - MIA
1 stop4h 26mDelta
Mon 10/206:15 pmMIA - CHS
1 stop5h 44mDelta
Deal found 9/24$177
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/165:35 amCHS - MIA
1 stop5h 29mDelta
Mon 10/206:15 pmMIA - CHS
1 stop5h 44mDelta
Deal found 9/23$178
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/109:10 pmCHS - MIA
1 stop20h 54mSpirit Airlines
Fri 10/179:49 amMIA - CHS
1 stop10h 26mSpirit Airlines
Deal found 9/24$183

Cheapflights Fare Finder

 
Customize your flight search to find flights from Charleston to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 24, 2025.
Use the filters below to find and compare flights from Charleston to Florida Keys that are best for you.

Fly from

Charleston

Fly to

Florida Keys

Route

Depart

Return

Price

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Mon 11/24

7:56 pm-9:38 pm

Nonstop1h 42m

Miami

Thu 11/27

8:00 pm-9:51 pm

Nonstop1h 51m

$120

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Tue 12/9

9:00 am-2:45 pm

1 stop5h 45m

Miami

Tue 12/16

7:00 am-1:24 pm

1 stop6h 24m

$167

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Tue 12/9

9:00 am-3:50 pm

1 stop6h 50m

Miami

Sat 12/13

7:00 am-1:06 pm

1 stop6h 06m

$167

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Fri 10/17

8:03 pm-12:29 am

1 stop4h 26m

Miami

Mon 10/20

6:15 pm-11:59 pm

1 stop5h 44m

$177

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Tue 12/9

9:00 am-2:45 pm

1 stop5h 45m

Miami

Wed 12/10

2:11 pm-7:29 pm

1 stop5h 18m

$187

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Fri 10/17

7:44 pm-9:26 pm

Nonstop1h 42m

Miami

Mon 10/20

6:20 am-1:19 pm

1 stop6h 59m

$189

CharlestonKey West

CHS - EYW

CHSEYW

Charleston

Thu 10/23

8:53 pm-9:17 am

1 stop12h 24m

Key West

Thu 10/30

8:55 am-8:57 am

1 stop24h 02m

$191

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Sat 10/11

6:55 pm-12:29 am

1 stop5h 34m

Miami

Sat 10/18

6:00 am-10:21 am

1 stop4h 21m

$198

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Fri 10/17

8:03 pm-12:29 am

1 stop4h 26m

Miami

Sun 10/19

6:00 am-10:20 am

1 stop4h 20m

$198

CharlestonMiami

CHS - MIA

CHSMIA

Charleston

Sat 11/8

6:55 pm-12:29 am

1 stop5h 34m

Miami

Sat 11/15

6:00 am-10:10 am

1 stop4h 10m

$198

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/23

Showing 1-10 of 40 results
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Best time to book a flight from Charleston to Florida Keys

Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Charleston with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Charleston to Florida Keys

What is the cheapest month to book a flight from Charleston to Florida Keys?

Currently, August is the cheapest month in which you can book a flight from Charleston to Florida Keys (average of $328). Flying from Charleston to Florida Keys in March is currently the most expensive (average of $489). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHS to EOA?

Find hourly flight availability from Charleston to Florida Keys. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 24, 2025.

When flying from Charleston to Florida Keys, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Florida Keys

Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated September 24, 2025.
Read reviews from past customers who have flown Southwest, Delta, and American Airlines from Charleston to Florida Keys. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,244 reviews

Comfort

8.0

Overall

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,244 reviews
Southwest
8.0
Very good
4,244 reviews

Comfort

8.0

Overall

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,973 reviews
Southwest
8.0
Very good
4,244 reviews

Comfort

8.0

Overall

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,244 reviews

Comfort

8.0

Overall

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
JetBlue
7.2
Good
2,911 reviews
Southwest
8.0
Very good
4,244 reviews

Comfort

8.0

Overall

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Spirit Airlines
6.3
Okay
8,042 reviews
Southwest
8.0
Very good
4,244 reviews

Comfort

8.0

Overall

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Charleston to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Charleston to Florida Keys?

    Charleston (CHS) is the airport you will fly out of if you book a flight from Charleston to Florida Keys. It is only a 10.2 mi journey to Charleston (CHS) from Charleston’s city center.

  • How long is the flight from Charleston to Florida Keys?

    There are many flights that can get you from Charleston to Florida Keys in 1h 42m. Fly via American Airlines, Delta, or Breeze Airways to get the fastest option. The distance from Charleston to Florida Keys is about 490 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Charleston to Florida Keys that include hotel bookings?

    Yes. In addition to deals on Charleston to Florida Keys flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Charleston to Florida Keys?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Charleston to Florida Keys.

  • Can I find deals for business class flights from Charleston to Florida Keys?

    Yes. Cheapflights offers flight deals from Charleston to Florida Keys by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Charleston to Florida Keys?

    Currently, August is the cheapest month in which you can book a flight from Charleston to Florida Keys (average of $328). Flying from Charleston to Florida Keys in March is currently the most expensive (average of $489). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Charleston to Florida Keys

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Top 2 airlines flying from Charleston to Florida Keys

Discover the top 2 airlines that operate flights from Charleston to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 24, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$286Average$513FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$336Average$540FlexibilityNo cancel feeOn-time71%

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