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$529+ Cheap flights from Knoxville (TYS) to Florence (FLR)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/26. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — FLR
Apr 21 — Apr 281
Tue 4/21
Tue 4/28
1 adult, Economy
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Cheap flight deals from Knoxville to Florence

Cheapest flights from Knoxville to Florence
Explore the most affordable flight options available from Knoxville to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 22, 2026.

This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/210:50 am
TYS
-
FLR
2 stops20h 45m
United Airlines
Sun 12/66:30 am
FLR
-
TYS
2 stops18h 47m
United Airlines
Deal found 3/19$812
This Cheapflightsfares deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/172:25 pm
TYS
-
FLR
2 stops20h 10m
Lufthansa
Fri 4/246:30 am
FLR
-
TYS
2 stops22h 04m
Lufthansa
Deal found 3/19$843
This United Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1711:25 am
TYS
-
FLR
2 stops19h 25m
United Airlines
Fri 4/246:30 am
FLR
-
TYS
2 stops23h 11m
United Airlines
Deal found 3/20$908
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/61:52 pm
TYS
-
FLR
2 stops20h 43m
United Airlines
Wed 5/136:30 am
FLR
-
TYS
2 stops20h 15m
United Airlines
Deal found 3/22$924
This United Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/72:00 pm
TYS
-
FLR
2 stops14h 40m
United Airlines
Thu 12/106:25 am
FLR
-
TYS
2 stops20h 40m
United Airlines
Deal found 3/20$952
This KAYAK deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/75:53 pm
TYS
-
FLR
2 stops16h 42m
Lufthansa
Tue 4/145:15 pm
FLR
-
TYS
2 stops35h 53m
Lufthansa
Deal found 3/21$960
This oojo deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/711:31 am
TYS
-
FLR
2 stops42h 04m
British Airways
Tue 4/1412:20 pm
FLR
-
TYS
2 stops39h 37m
British Airways
Deal found 3/18$984

Find flight deals from Knoxville to Florence

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Florence (FLR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 22, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$843
(Cheapflightsfares)

One-way from

$529
(Kiwi.com)
Provider with most accurate pricing for Knoxville McGhee Tyson-Florence Peretola flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Florence Peretola flights.
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From Knoxville McGhee Tyson to Florence Peretola
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One-way flight from Knoxville McGhee Tyson to Florence Peretola
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
Use the filters below to find and compare flights from Knoxville to Florence that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Fri 4/17

2:25 pm-4:35 pm

2 stops20h 10m

Florence Peretola

Fri 4/24

6:30 am-10:34 pm

2 stops22h 04m

$843

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Fri 4/17

11:25 am-12:50 pm

2 stops19h 25m

Florence Peretola

Fri 4/24

6:30 am-11:41 pm

2 stops23h 11m

$908

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Wed 5/6

1:52 pm-4:35 pm

2 stops20h 43m

Florence Peretola

Wed 5/13

6:30 am-8:45 pm

2 stops20h 15m

$924

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Fri 5/8

7:18 pm-8:15 pm

2 stops18h 57m

Florence Peretola

Mon 5/18

2:00 pm-8:12 pm

2 stops36h 12m

$991

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Thu 6/11

7:19 pm-4:35 pm

2 stops15h 16m

Florence Peretola

Sun 6/28

8:15 am-11:54 pm

2 stops21h 39m

$1,276
Quickest round-trip

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Fri 4/17

1:52 pm-10:40 am

2 stops14h 48m

Florence Peretola

Sat 4/25

1:20 pm-10:34 pm

2 stops15h 14m

$1,375

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Tue 5/19

9:50 am-12:40 pm

2 stops20h 50m

Florence Peretola

Sun 5/31

6:30 am-8:34 pm

2 stops20h 04m

$1,449
Cheapest one-way
Quickest one-way

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Fri 6/26

7:10 am-10:40 am

3 stops45h 30m

$529

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/21

Sorted by cheapest first

Compare providers for flights from Knoxville to Florence

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Florence in March.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Florence flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Florence flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Florence flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Florence flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Florence flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Florence

Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated March 22, 2026.
Read through reviews of airlines operating flights from Knoxville to Florence, such as United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,455 reviews

Entertainment

7.1

Food

6.6

Boarding

7.7

Overall

7.4

Crew

8.1

Comfort

7.3

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
United Airlines
7.4
Good
9,455 reviews
United Airlines
7.4
Good
9,455 reviews

Entertainment

7.1

Food

6.6

Boarding

7.7

Overall

7.4

Crew

8.1

Comfort

7.3

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Florence?

    Lufthansa and United Airlines can get you from Knoxville to Florence in just under 19h 25m. Your travel time can differ by up to 45m. The distance between Knoxville and Florence is about 4791 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Knoxville to Florence round-trip?

    United Airlines, at $564, was found to be the cheapest airline from Knoxville to Florence..

  • Can I find deals for flights from Knoxville to Florence that include hotel bookings?

    Yes. In addition to deals on Knoxville to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Florence.

  • Can I find deals for business class flights from Knoxville to Florence?

    Yes. Cheapflights offers flight deals from Knoxville to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Pistoia
Arezzo

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Knoxville to Florence

Discover the top airline that operate flights from Knoxville to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$564Average$1,094FlexibilityNo cancel feeOn-time69%

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