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$265+ Cheap flights from Knoxville (TYS) to Florence (FLR)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/26. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — FLR
Dec 19 — Dec 261
Fri 12/19
Fri 12/26
1 adult, Economy
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Cheap flight deals from Knoxville to Florence

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Florence (FLR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 19, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$498
(United Airlines)

One-way from

$265
(Mytrip)

Popular in

March

Cheapest in

October

Average price

$1,074
Provider with most accurate pricing for Knoxville McGhee Tyson-Florence Peretola flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Florence Peretola flights.
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From Knoxville McGhee Tyson to Florence Peretola
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One-way flight from Knoxville McGhee Tyson to Florence Peretola
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Highest demand for flights based on searches. 13% potential increase in price ($201 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($48 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Knoxville to Florence

Cheapest flights from Knoxville to Florence
Explore the most affordable flight options available from Knoxville to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 19, 2025.

This Mytrip deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/215:10 pmTYS - FLR
2 stops23h 55mMultiple Airlines
Sun 11/236:55 amFLR - TYS
3 stops21h 08mMultiple Airlines
Deal found 11/17$1,457

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 19, 2025.
Use the filters below to find and compare flights from Knoxville to Florence that are best for you.

Fly from

Knoxville

Fly to

Florence

Route

Depart

Return

Price

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Fri 2/6

2:25 pm-12:35 pm

2 stops16h 10m

Florence Peretola

Tue 2/10

6:30 am-11:44 pm

2 stops23h 14m

$498

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Thu 5/7

2:30 pm-11:30 am

2 stops39h 00m

Florence Peretola

Sun 5/17

7:55 pm-9:44 pm

2 stops31h 49m

$1,102

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Thu 5/7

10:16 am-9:35 am

3 stops17h 19m

Florence Peretola

Sun 5/17

6:30 am-7:17 pm

3 stops18h 47m

$4,266

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Mon 1/26

12:55 pm-6:05 pm

2 stops23h 10m

$265

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Mon 1/26

5:29 pm-4:30 pm

2 stops17h 01m

$2,803

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/18

Compare providers for flights from Knoxville to Florence

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Florence in November.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*2 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Florence flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Knoxville-Florence flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Knoxville-Florence flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Florence flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Florence flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Florence

What is the cheapest month to book a flight from Knoxville to Florence?

Currently, July is the cheapest month in which you can book a flight from Knoxville to Florence (average of $665). Flying from Knoxville to Florence in June is currently the most expensive (average of $1,262). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to FLR?

Find hourly flight availability from Knoxville to Florence. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 19, 2025.

One of the essential ways to save on airfare from Knoxville to Florence is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the afternoon could potentially save you up to 32% on airfare.

Reviews of airlines servicing Florence

Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated November 19, 2025.
Read through reviews of airlines operating flights from Knoxville to Florence, such as Delta, United Airlines, and Lufthansa. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,003 reviews

Comfort

7.9

Overall

7.9

Boarding

8.1

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,003 reviews
Delta
7.9
Good
8,003 reviews

Comfort

7.9

Overall

7.9

Boarding

8.1

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,022 reviews
Delta
7.9
Good
8,003 reviews

Comfort

7.9

Overall

7.9

Boarding

8.1

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Lufthansa
6.8
Okay
7,579 reviews
Delta
7.9
Good
8,003 reviews

Comfort

7.9

Overall

7.9

Boarding

8.1

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Florence?

    United Airlines, Scandinavian Airlines, and Air Canada can get you from Knoxville to Florence in just under 16h 10m. Your travel time can differ by up to 22h 50m. The distance between Knoxville and Florence is about 4791 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Knoxville to Florence round-trip?

    Lufthansa, at $649, was found to be the cheapest airline from Knoxville to Florence.Alternate airlines to your destination round-trip include Delta and United Airlines. Lufthansa is priced at 47% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Knoxville to Florence that include hotel bookings?

    Yes. In addition to deals on Knoxville to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Florence.

  • Can I find deals for business class flights from Knoxville to Florence?

    Yes. Cheapflights offers flight deals from Knoxville to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Florence?

    Currently, July is the cheapest month in which you can book a flight from Knoxville to Florence (average of $665). Flying from Knoxville to Florence in June is currently the most expensive (average of $1,262). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Knoxville to Florence

Discover the top 3 airlines that operate flights from Knoxville to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 19, 2025.
AirlineCheapestAverageFlexibilityOn-time
LufthansaCheapest$649Average$1,106FlexibilityNo cancel feeOn-time76%
DeltaCheapest$832Average$1,279FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$894Average$1,147FlexibilityNo cancel feeOn-time69%

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