$649+ Cheap flights from Knoxville (TYS) to Florence (FLR)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/17. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — FLR
Oct 25 — Nov 11
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Florence with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Florence
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Best
Last-minute
Cheapest flights from Knoxville to FlorenceExplore the most affordable flight options available from Knoxville to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 25, 2026.
Explore the most affordable flight options available from Knoxville to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 25, 2026.
This Air France deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/172:40 pm -
2 stops14h 55m
Tue 11/246:25 am -
2 stops17h 24m
Deal found 9/20![Air France logo]()
$649
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:22 pm -
2 stops18h 28m
Thu 12/36:40 am -
2 stops20h 53m
Deal found 9/21![Delta logo]()
$667
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:10 pm -
2 stops14h 15m
Fri 12/46:50 am -
2 stops16h 40m
Deal found 9/21![Delta logo]()
$717
This Air France deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:18 pm -
2 stops15h 27m
Wed 11/46:25 am -
2 stops19h 24m
Deal found 9/20![Air France logo]()
$718
This Expedia deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:45 pm -
2 stops18h 30m
Sat 12/125:00 pm -
2 stops36h 59m
Deal found 9/22![Lufthansa logo]()
$722
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/121:55 pm -
2 stops18h 00m
Thu 11/196:30 am -
2 stops23h 29m
Deal found 9/22![United Airlines logo]()
$724
This KLM deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/45:00 pm -
2 stops17h 25m
Wed 11/116:25 am -
2 stops17h 24m
Deal found 9/20![Multiple Airlines logo]()
$728
This Expedia deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:35 pm -
2 stops18h 40m
Sat 11/2110:20 am -
2 stops15h 16m
Deal found 9/22![Lufthansa logo]()
$731
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/155:45 am -
2 stops28h 35m
Wed 12/21:10 pm -
2 stops36h 37m
Deal found 9/21![United Airlines logo]()
$732
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:10 pm -
2 stops14h 15m
Tue 12/112:15 pm -
2 stops16h 02m
Deal found 9/21![Delta logo]()
$734
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1411:20 am -
2 stops23h 00m
Wed 12/21:10 pm -
2 stops37h 27m
Deal found 9/21![United Airlines logo]()
$738
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1711:43 am -
2 stops16h 57m
Mon 11/301:05 pm -
2 stops35h 17m
Deal found 9/21![Delta logo]()
$745
Best flights from Knoxville to FlorenceDiscover carefully curated flight deals from Knoxville to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 25, 2026.
Discover carefully curated flight deals from Knoxville to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 25, 2026.
This Air France deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/172:40 pm -
2 stops14h 55m
Tue 11/246:25 am -
2 stops17h 24m
Deal found 9/20![Air France logo]()
$649
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:22 pm -
2 stops18h 28m
Thu 12/311:20 am -
2 stops18h 37m
Deal found 9/21![Delta logo]()
$667
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/121:55 pm -
2 stops18h 00m
Thu 11/196:30 am -
2 stops23h 29m
Deal found 9/22![United Airlines logo]()
$724
This KLM deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/45:00 pm -
2 stops17h 25m
Wed 11/116:25 am -
2 stops17h 24m
Deal found 9/20![Multiple Airlines logo]()
$728
This Expedia deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:35 pm -
2 stops18h 40m
Sat 11/2110:20 am -
2 stops15h 16m
Deal found 9/22![Lufthansa logo]()
$731
This Air Canada deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:45 am -
3 stops17h 55m
Wed 11/46:30 am -
3 stops23h 29m
Deal found 9/23![Air Canada logo]()
$773
This Air France deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:18 pm -
2 stops15h 27m
Wed 11/46:25 am -
2 stops19h 24m
Deal found 9/23![Air France logo]()
$718
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:43 am -
2 stops22h 42m
Mon 11/301:05 pm -
2 stops35h 17m
Deal found 9/21![Delta logo]()
$842
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:10 am -
2 stops21h 30m
Mon 11/301:05 pm -
2 stops35h 17m
Deal found 9/21![Delta logo]()
$842
This Air Canada deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:45 am -
3 stops21h 55m
Thu 11/196:30 am -
3 stops23h 29m
Deal found 9/22![Air Canada logo]()
$938
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:45 am -
2 stops22h 25m
Wed 11/41:10 pm -
2 stops40h 49m
Deal found 9/24![United Airlines logo]()
$983
Last-minute flights from Knoxville to FlorenceDiscover last-minute flight deals from Knoxville to Florence. Data last updated September 25, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Florence. Data last updated September 25, 2026 and is based on user searches.
This KAYAK deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3010:42 am -
2 stops17h 18m
Tue 10/69:55 am -
2 stops29h 50m
Deal found 9/21![SWISS logo]()
$1,017
This Gurufare deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3010:42 am -
2 stops17h 18m
Tue 10/66:30 am -
2 stops20h 19m
Deal found 9/22![Multiple Airlines logo]()
$1,020
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:25 pm -
2 stops36h 45m
Tue 10/68:15 am -
2 stops21h 44m
Deal found 9/25![United Airlines logo]()
$1,144
This Ovago deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:03 pm -
2 stops16h 32m
Fri 10/91:25 pm -
2 stops16h 34m
Deal found 9/22![Lufthansa logo]()
$1,397
This Air France deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/215:18 pm -
2 stops15h 27m
Wed 11/46:25 am -
2 stops19h 24m
Deal found 9/20![Air France logo]()
$718
This Air Canada deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:45 am -
3 stops17h 55m
Wed 11/46:30 am -
3 stops23h 29m
Deal found 9/23![Air Canada logo]()
$773
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:45 am -
2 stops22h 25m
Wed 11/41:10 pm -
2 stops40h 49m
Deal found 9/24![United Airlines logo]()
$983
This KAYAK deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/255:45 am -
2 stops27h 20m
Sat 10/315:00 pm -
2 stops36h 59m
Deal found 9/21![Multiple Airlines logo]()
$1,080
Find flight deals from Knoxville to Florence
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Florence (FLR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $649 (Air France) |
Popular in | March |
Cheapest in | January |
Average price | $1,105 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 25, 2026.
Use the filters below to find and compare flights from Knoxville to Florence that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
KnoxvilleFlorence
TYS Knoxville McGhee Tyson - FLR Florence Peretola
TYSFLR
Knoxville McGhee Tyson
Tue 11/17
2:40 pm-11:35 am
2 stops14h 55m
Florence Peretola
Tue 11/24
6:25 am-5:49 pm
2 stops17h 24m
$649
KnoxvilleFlorence
TYS Knoxville McGhee Tyson - FLR Florence Peretola
TYSFLR
Knoxville McGhee Tyson
Mon 11/16
7:22 pm-7:50 pm
2 stops18h 28m
Florence Peretola
Thu 12/3
11:20 am-11:57 pm
2 stops18h 37m
$667
KnoxvilleFlorence
TYS Knoxville McGhee Tyson - FLR Florence Peretola
TYSFLR
Knoxville McGhee Tyson
Wed 10/21
5:18 pm-2:45 pm
2 stops15h 27m
Florence Peretola
Wed 11/4
6:25 am-7:49 pm
2 stops19h 24m
$718
KnoxvilleFlorence
TYS Knoxville McGhee Tyson - FLR Florence Peretola
TYSFLR
Knoxville McGhee Tyson
Thu 11/12
1:55 pm-1:55 pm
2 stops18h 00m
Florence Peretola
Thu 11/19
6:30 am-11:59 pm
2 stops23h 29m
$724
KnoxvilleFlorence
TYS Knoxville McGhee Tyson - FLR Florence Peretola
TYSFLR
Knoxville McGhee Tyson
Wed 11/4
5:00 pm-4:25 pm
2 stops17h 25m
Florence Peretola
Wed 11/11
6:25 am-5:49 pm
2 stops17h 24m
$728
KnoxvilleFlorence
TYS Knoxville McGhee Tyson - FLR Florence Peretola
TYSFLR
Knoxville McGhee Tyson
Fri 11/13
7:35 pm-8:15 pm
2 stops18h 40m
Florence Peretola
Sat 11/21
10:20 am-7:36 pm
2 stops15h 16m
$731
KnoxvilleFlorence
TYS Knoxville McGhee Tyson - FLR Florence Peretola
TYSFLR
Knoxville McGhee Tyson
Wed 10/21
9:45 am-9:40 am
3 stops17h 55m
Florence Peretola
Wed 11/4
6:30 am-11:59 pm
3 stops23h 29m
$773
KnoxvilleFlorence
TYS Knoxville McGhee Tyson - FLR Florence Peretola
TYSFLR
Knoxville McGhee Tyson
Wed 11/18
11:43 am-4:25 pm
2 stops22h 42m
Florence Peretola
Mon 11/30
1:05 pm-6:22 pm
2 stops35h 17m
$842
KnoxvilleFlorence
TYS Knoxville McGhee Tyson - FLR Florence Peretola
TYSFLR
Knoxville McGhee Tyson
Mon 11/16
7:10 am-10:40 am
2 stops21h 30m
Florence Peretola
Mon 11/30
1:05 pm-6:22 pm
2 stops35h 17m
$842
KnoxvilleFlorence
TYS Knoxville McGhee Tyson - FLR Florence Peretola
TYSFLR
Knoxville McGhee Tyson
Thu 11/12
5:45 am-9:40 am
3 stops21h 55m
Florence Peretola
Thu 11/19
6:30 am-11:59 pm
3 stops23h 29m
$938
Showing 1-10 of 11 resultsSorted by cheapest first
Compare providers for flights from Knoxville to Florence
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Florence in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-Florence flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Florence flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Florence flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Florence flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Florence flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Florence
Have a flexible travel schedule? Discover the best time to fly to Florence from Knoxville with our price prediction graph.
TYS-FLR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Florence
Reviews of airlines servicing Florence
Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated September 25, 2026.
Read through reviews of airlines operating flights from Knoxville to Florence, such as Lufthansa. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
6.3
Comfort
6.8
Overall
6.8
Entertainment
6.5
Boarding
7.0
Crew
7.6
Reviews
1 / 20
6.0
GoodKunal,Jul 2026
LAX - MUC
Food
6.3
Comfort
6.8
Overall
6.8
Entertainment
6.5
Boarding
7.0
Crew
7.6
Reviews
1 / 20
6.0
GoodKunal,Jul 2026
LAX - MUC
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Florence?
Book flights to Florence if you plan to visit one of these locationsPistoia
Prato
Arezzo
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Complete your trip to Florence by adding a car rental and/or hotel reservation to your travel itinerary.
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Other flights to Florence
Explore flights to Florence departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 25, 2026.
Knoxville and Florence flights
Browse other Knoxville and Florence flight options. Last updated on September 25, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on September 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Knoxville to Florence
Discover the top airline that operate flights from Knoxville to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$759 | Average$1,105 | FlexibilityNo cancel fee | On-time76% |