$420+ Cheap flights from Knoxville (TYS) to Florence (FLR)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/14. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — FLR
Jul 5 — Jul 121
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Knoxville to Florence with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Florence
Cheapest
Best
Last-minute
One-way
Cheapest flights from Knoxville to FlorenceExplore the most affordable flight options available from Knoxville to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 5, 2026.
Explore the most affordable flight options available from Knoxville to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 5, 2026.
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:45 am
TYS
- FLR
2 stops19h 15m
United Airlines
Wed 11/42:20 pm
FLR
- TYS
2 stops49h 39m
United Airlines
Deal found 6/4![United Airlines logo]()
$810
This Delta deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:18 pm
TYS
- FLR
2 stops17h 57m
Delta
Wed 9/3011:20 am
FLR
- TYS
2 stops18h 30m
Delta
Deal found 6/2![Delta logo]()
$916
This Ovago deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/191:35 pm
TYS
- FLR
2 stops21h 00m
Lufthansa
Sun 7/269:50 am
FLR
- TYS
2 stops20h 04m
Lufthansa
Deal found 6/4![Lufthansa logo]()
$976
This United Airlines deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:02 pm
TYS
- FLR
2 stops36h 48m
United Airlines
Sun 9/136:30 am
FLR
- TYS
2 stops21h 15m
United Airlines
Deal found 6/4![United Airlines logo]()
$998
This Cheapflightsfares deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:02 pm
TYS
- FLR
2 stops20h 13m
Lufthansa
Sat 9/199:50 am
FLR
- TYS
2 stops18h 57m
Lufthansa
Deal found 6/4![Lufthansa logo]()
$1,018
This Cheapflightsfares deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1610:00 am
TYS
- FLR
2 stops22h 00m
Lufthansa
Thu 7/238:15 am
FLR
- TYS
2 stops21h 39m
Lufthansa
Deal found 6/1![Lufthansa logo]()
$1,034
This KAYAK deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:02 pm
TYS
- FLR
2 stops44h 13m
Lufthansa
Sun 9/136:30 am
FLR
- TYS
2 stops22h 17m
Lufthansa
Deal found 6/1![Lufthansa logo]()
$1,046
This KAYAK deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:02 pm
TYS
- FLR
2 stops18h 28m
Multiple Airlines
Sat 9/196:30 am
FLR
- TYS
2 stops16h 28m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$1,108
Best flights from Knoxville to FlorenceDiscover carefully curated flight deals from Knoxville to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 5, 2026.
Discover carefully curated flight deals from Knoxville to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 5, 2026.
This Ovago deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/191:35 pm
TYS
- FLR
2 stops21h 00m
Lufthansa
Sun 7/269:50 am
FLR
- TYS
2 stops20h 04m
Lufthansa
Deal found 6/4![Lufthansa logo]()
$976
This KAYAK deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:02 pm
TYS
- FLR
2 stops18h 28m
Multiple Airlines
Sat 9/196:30 am
FLR
- TYS
2 stops16h 28m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$1,108
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:20 pm
TYS
- FLR
2 stops15h 15m
United Airlines
Sat 9/196:25 am
FLR
- TYS
3 stops22h 24m
United Airlines
Deal found 6/5![United Airlines logo]()
$1,447
This Cheapflightsfares deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:02 pm
TYS
- FLR
2 stops20h 13m
Lufthansa
Sat 9/199:50 am
FLR
- TYS
2 stops18h 57m
Lufthansa
Deal found 6/4![Lufthansa logo]()
$1,018
This Cheapflightsfares deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1610:00 am
TYS
- FLR
2 stops22h 00m
Lufthansa
Thu 7/238:15 am
FLR
- TYS
2 stops21h 39m
Lufthansa
Deal found 6/1![Lufthansa logo]()
$1,034
This Air Canada deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/39:45 am
TYS
- FLR
3 stops17h 45m
Air Canada
Sat 9/196:30 am
FLR
- TYS
3 stops19h 54m
Air Canada
Deal found 6/5![Air Canada logo]()
$3,018
Last-minute flights from Knoxville to FlorenceDiscover last-minute flight deals from Knoxville to Florence. Data last updated June 5, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Florence. Data last updated June 5, 2026 and is based on user searches.
This Cheapflightsfares deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1610:00 am
TYS
- FLR
2 stops22h 00m
Lufthansa
Thu 7/238:15 am
FLR
- TYS
2 stops21h 39m
Lufthansa
Deal found 6/1![Lufthansa logo]()
$1,034
This Air Canada deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/1610:00 am
TYS
- FLR
3 stops17h 30m
Air Canada
Thu 7/2311:20 am
FLR
- TYS
3 stops18h 34m
Air Canada
Deal found 6/1![Air Canada logo]()
$2,222
This Ovago deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/191:35 pm
TYS
- FLR
2 stops21h 00m
Lufthansa
Sun 7/269:50 am
FLR
- TYS
2 stops20h 04m
Lufthansa
Deal found 6/4![Lufthansa logo]()
$976
This Air Canada deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/1910:00 am
TYS
- FLR
3 stops17h 40m
Air Canada
Sun 7/266:30 am
FLR
- TYS
3 stops20h 04m
Air Canada
Deal found 6/4![Air Canada logo]()
$3,399
One-way flights from Knoxville to FlorenceSearch for one-way flight options from Knoxville to Florence. Find affordable one-way fares based on user searches. Data last updated June 5, 2026.
Search for one-way flight options from Knoxville to Florence. Find affordable one-way fares based on user searches. Data last updated June 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/149:10 am
TYS
- FLR
3 stops31h 45m
Multiple Airlines
Deal found 6/5![Multiple Airlines logo]()
$420
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/146:04 pm
TYS
- FLR
2 stops22h 16m
American Airlines
Deal found 6/5![American Airlines logo]()
$424
Find flight deals from Knoxville to Florence
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Florence (FLR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $810 (United Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 5, 2026.
Use the filters below to find and compare flights from Knoxville to Florence that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleFlorence
TYS - FLR
TYSFLR
Knoxville McGhee Tyson
Sun 7/19
1:35 pm-4:35 pm
2 stops21h 00m
Florence Peretola
Sun 7/26
9:50 am-11:54 pm
2 stops20h 04m
$976
KnoxvilleFlorence
TYS - FLR
TYSFLR
Knoxville McGhee Tyson
Thu 9/3
6:02 pm-8:15 pm
2 stops20h 13m
Florence Peretola
Sat 9/19
9:50 am-10:47 pm
2 stops18h 57m
$1,018
KnoxvilleFlorence
TYS - FLR
TYSFLR
Knoxville McGhee Tyson
Thu 7/16
10:00 am-2:00 pm
2 stops22h 00m
Florence Peretola
Thu 7/23
8:15 am-11:54 pm
2 stops21h 39m
$1,034
Quickest round-trip
KnoxvilleFlorence
TYS - FLR
TYSFLR
Knoxville McGhee Tyson
Thu 9/3
6:02 pm-6:30 pm
2 stops18h 28m
Florence Peretola
Sat 9/19
6:30 am-4:58 pm
2 stops16h 28m
$1,108
KnoxvilleFlorence
TYS - FLR
TYSFLR
Knoxville McGhee Tyson
Thu 9/3
7:20 pm-4:35 pm
2 stops15h 15m
Florence Peretola
Sat 9/19
6:25 am-10:49 pm
3 stops22h 24m
$1,447
KnoxvilleFlorence
TYS - FLR
TYSFLR
Knoxville McGhee Tyson
Thu 9/3
9:45 am-9:30 am
3 stops17h 45m
Florence Peretola
Sat 9/19
6:30 am-8:24 pm
3 stops19h 54m
$3,018
Cheapest one-way
KnoxvilleFlorence
TYS - FLR
TYSFLR
Knoxville McGhee Tyson
Mon 9/14
9:10 am-10:55 pm
3 stops31h 45m
$420
Quickest one-way
KnoxvilleFlorence
TYS - FLR
TYSFLR
Knoxville McGhee Tyson
Mon 9/14
6:04 pm-10:20 pm
2 stops22h 16m
$424
Sorted by cheapest first
Compare providers for flights from Knoxville to Florence
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Florence in June.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-Florence flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Florence flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Florence flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Florence flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Florence flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Florence
Have a flexible travel schedule? Discover the best time to fly to Florence from Knoxville with our price prediction graph.
TYS-FLR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Florence
Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated June 5, 2026.
Read through reviews of airlines operating flights from Knoxville to Florence, such as United Airlines and Lufthansa. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.7
Food
6.6
Crew
8.1
Entertainment
7.1
Comfort
7.3
Overall
7.4
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Boarding
7.7
Food
6.6
Crew
8.1
Entertainment
7.1
Comfort
7.3
Overall
7.4
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Boarding
7.7
Food
6.6
Crew
8.1
Entertainment
7.1
Comfort
7.3
Overall
7.4
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Florence?
Book flights to Florence if you plan to visit one of these locationsPistoia
Arezzo
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Florence flight routes
Other flight options
Other flights from Knoxville
Popular flights
Alternative routes for Knoxville to Florence
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Florence by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Knoxville to Florence by cabin class
Find flights from Knoxville to Florence, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Florence
Explore flights to Florence departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on June 5, 2026.
Knoxville and Florence flights
Browse other Knoxville and Florence flight options. Last updated on June 5, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on June 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Knoxville to Florence
Discover the top 2 airlines that operate flights from Knoxville to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$564 | Average$1,005 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$649 | Average$1,104 | FlexibilityNo cancel fee | On-time76% |