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$668+ Cheap flights from Knoxville (TYS) to Florence (FLR)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/1. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — FLR
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Knoxville to Florence

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Florence (FLR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2025.

Round-trip from

$668
(United Airlines)
From Knoxville McGhee Tyson to Florence Peretola
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Find flight deals from Knoxville to Florence

Cheapest flights from Knoxville to Florence
Explore the most affordable flight options available from Knoxville to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/17:20 pmTYS - FLR
2 stops37h 50mUnited Airlines
Sat 11/82:15 pmFLR - TYS
2 stops50h 33mUnited Airlines
Deal found 9/17$668
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3112:47 pmTYS - FLR
2 stops17h 53mDelta
Fri 11/712:15 pmFLR - TYS
2 stops17h 31mDelta
Deal found 9/15$679
This Cheapflightsfares deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/317:20 pmTYS - FLR
2 stops16h 10mLufthansa
Sat 11/88:00 amFLR - TYS
2 stops21h 59mLufthansa
Deal found 9/16$688
This Orbitz deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/17:26 pmTYS - FLR
2 stops18h 49mLufthansa
Mon 10/135:25 pmFLR - TYS
2 stops35h 25mLufthansa
Deal found 9/17$750
This Mytrip deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/316:23 pmTYS - FLR
3 stops23h 17mMultiple Airlines
Fri 11/76:55 amFLR - TYS
3 stops21h 31mMultiple Airlines
Deal found 9/15$884
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/17:00 amTYS - FLR
3 stops23h 55mUnited Airlines
Mon 10/138:15 amFLR - TYS
2 stops36h 30mUnited Airlines
Deal found 9/17$907
This Mytrip deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/13:21 pmTYS - FLR
3 stops23h 59mMultiple Airlines
Mon 10/136:50 amFLR - TYS
3 stops22h 26mMultiple Airlines
Deal found 9/17$1,075
This Mytrip deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/17:30 amTYS - FLR
3 stops34h 35mMultiple Airlines
Sat 11/89:50 amFLR - TYS
3 stops34h 15mMultiple Airlines
Deal found 9/17$1,980
This Air Canada deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/319:50 amTYS - FLR
3 stops22h 45mAir Canada
Sat 11/86:30 amFLR - TYS
3 stops19h 50mAir Canada
Deal found 9/16$2,400

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Knoxville to Florence that are best for you.

Fly from

Knoxville

Fly to

Florence

Route

Depart

Return

Price

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Sat 11/1

7:20 pm-2:10 pm

2 stops37h 50m

Florence Peretola

Sat 11/8

2:15 pm-10:48 am

2 stops50h 33m

$668

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Fri 10/31

12:47 pm-11:40 am

2 stops17h 53m

Florence Peretola

Fri 11/7

12:15 pm-11:46 pm

2 stops17h 31m

$679

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Fri 10/31

7:20 pm-4:30 pm

2 stops16h 10m

Florence Peretola

Sat 11/8

8:00 am-11:59 pm

2 stops21h 59m

$688

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Wed 10/1

7:26 pm-8:15 pm

2 stops18h 49m

Florence Peretola

Mon 10/13

5:25 pm-10:50 pm

2 stops35h 25m

$750

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Fri 10/31

6:23 pm-10:40 pm

3 stops23h 17m

Florence Peretola

Fri 11/7

6:55 am-10:26 pm

3 stops21h 31m

$884

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Wed 10/1

7:00 am-12:55 pm

3 stops23h 55m

Florence Peretola

Mon 10/13

8:15 am-2:45 pm

2 stops36h 30m

$907

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Wed 10/1

3:21 pm-9:20 pm

3 stops23h 59m

Florence Peretola

Mon 10/13

6:50 am-11:16 pm

3 stops22h 26m

$1,075

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Sat 11/1

7:30 am-11:05 pm

3 stops34h 35m

Florence Peretola

Sat 11/8

9:50 am-2:05 pm

3 stops34h 15m

$1,980

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Fri 10/31

9:50 am-1:35 pm

3 stops22h 45m

Florence Peretola

Sat 11/8

6:30 am-8:20 pm

3 stops19h 50m

$2,400

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/17

Best time to book a flight from Knoxville to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Florence

What is the cheapest time of day to fly from TYS to FLR?

Find hourly flight availability from Knoxville to Florence. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

One of the essential ways to save on airfare from Knoxville to Florence is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the afternoon could potentially save you up to 33% on airfare.

Reviews of airlines servicing Florence

Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated September 17, 2025.
Read through reviews of airlines operating flights from Knoxville to Florence, such as Delta, United Airlines, and Lufthansa. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,961 reviews
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,926 reviews
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Lufthansa
6.8
Okay
7,409 reviews
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Florence?

    United Airlines, Delta, and Lufthansa can get you from Knoxville to Florence in just under 16h 10m. Your travel time can differ by up to 21h 40m. The distance between Knoxville and Florence is about 4791 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Knoxville to Florence round-trip?

    Lufthansa, at $649, was found to be the cheapest airline from Knoxville to Florence.Alternate airlines to your destination round-trip include Delta and United Airlines.

  • Can I find deals for flights from Knoxville to Florence that include hotel bookings?

    Yes. In addition to deals on Knoxville to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Florence.

  • Can I find deals for business class flights from Knoxville to Florence?

    Yes. Cheapflights offers flight deals from Knoxville to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Florence?

    Currently, November is the cheapest month in which you can book a flight from Knoxville to Florence (average of $754). Flying from Knoxville to Florence in June is currently the most expensive (average of $1,294). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Knoxville to Florence

Discover the top 3 airlines that operate flights from Knoxville to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
LufthansaCheapest$649Average$1,106FlexibilityNo cancel feeOn-time76%
DeltaCheapest$832Average$1,279FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$894Average$1,147FlexibilityNo cancel feeOn-time69%

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