$426+ Cheap flights from Knoxville (TYS) to Florence (FLR)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/12. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — FLR
Nov 19 — Nov 261
Round-trip
1 adult, Economy
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Find cheap flights from Knoxville to Florence with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Florence
Cheapest
Best
Last-minute
One-way
Cheapest flights from Knoxville to FlorenceExplore the most affordable flight options available from Knoxville to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 20, 2026.
Explore the most affordable flight options available from Knoxville to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 20, 2026.
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/301:55 pm -
2 stops17h 55m
Mon 12/71:10 pm -
2 stops37h 37m
Deal found 10/16![United Airlines logo]()
$834
This KAYAK deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:25 pm -
2 stops18h 50m
Wed 11/46:55 pm -
2 stops28h 04m
Deal found 10/16![Multiple Airlines logo]()
$1,016
This Justfly.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/257:35 pm -
2 stops18h 40m
Sun 11/295:00 pm -
2 stops36h 59m
Deal found 10/16![Lufthansa logo]()
$1,088
This Air Canada deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:45 am -
3 stops17h 55m
Wed 11/46:30 am -
3 stops23h 29m
Deal found 10/17![Air Canada logo]()
$1,092
This Air Canada deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/305:45 am -
3 stops21h 55m
Mon 12/76:30 am -
3 stops23h 29m
Deal found 10/16![Air Canada logo]()
$1,641
This Air Canada deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:45 am -
3 stops21h 55m
Sun 11/296:30 am -
3 stops19h 06m
Deal found 10/16![Air Canada logo]()
$3,822
Best flights from Knoxville to FlorenceDiscover carefully curated flight deals from Knoxville to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 20, 2026.
Discover carefully curated flight deals from Knoxville to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 20, 2026.
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/187:20 pm -
2 stops15h 05m
Sat 1/2312:20 pm -
2 stops17h 26m
Deal found 10/19![Delta logo]()
$799
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/1812:20 pm -
2 stops19h 30m
Fri 1/229:50 am -
2 stops20h 09m
Deal found 10/16![United Airlines logo]()
$815
This Justfly.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/257:35 pm -
2 stops18h 40m
Sun 11/295:00 pm -
2 stops36h 59m
Deal found 10/16![Lufthansa logo]()
$1,088
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1110:05 am -
2 stops19h 25m
Tue 4/206:30 am -
2 stops23h 16m
Deal found 10/15![Delta logo]()
$831
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/301:55 pm -
2 stops17h 55m
Mon 12/71:10 pm -
2 stops37h 37m
Deal found 10/16![United Airlines logo]()
$834
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/142:04 pm -
2 stops17h 51m
Tue 1/199:50 am -
2 stops20h 09m
Deal found 10/19![United Airlines logo]()
$877
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/75:57 pm -
2 stops16h 28m
Tue 1/196:40 am -
2 stops17h 33m
Deal found 10/19![Delta logo]()
$881
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/142:04 pm -
2 stops17h 51m
Sun 1/249:50 am -
2 stops20h 09m
Deal found 10/19![United Airlines logo]()
$927
Last-minute flights from Knoxville to FlorenceDiscover last-minute flight deals from Knoxville to Florence. Data last updated October 20, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Florence. Data last updated October 20, 2026 and is based on user searches.
This KAYAK deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:25 pm -
2 stops18h 50m
Wed 11/46:55 pm -
2 stops28h 04m
Deal found 10/16![Multiple Airlines logo]()
$1,016
This Air Canada deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:45 am -
3 stops17h 55m
Wed 11/46:30 am -
3 stops23h 29m
Deal found 10/17![Air Canada logo]()
$1,092
This Justfly.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/257:35 pm -
2 stops18h 40m
Sun 11/295:00 pm -
2 stops36h 59m
Deal found 10/16![Lufthansa logo]()
$1,088
This Air Canada deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/255:45 am -
3 stops21h 55m
Sun 11/296:30 am -
3 stops19h 06m
Deal found 10/16![Air Canada logo]()
$3,822
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/301:55 pm -
2 stops17h 55m
Mon 12/71:10 pm -
2 stops37h 37m
Deal found 10/16![United Airlines logo]()
$834
This Air Canada deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/305:45 am -
3 stops21h 55m
Mon 12/76:30 am -
3 stops23h 29m
Deal found 10/16![Air Canada logo]()
$1,641
One-way flights from Knoxville to FlorenceSearch for one-way flight options from Knoxville to Florence. Find affordable one-way fares based on user searches. Data last updated October 20, 2026.
Search for one-way flight options from Knoxville to Florence. Find affordable one-way fares based on user searches. Data last updated October 20, 2026.
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/128:48 pm -
2 stops19h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![American Airlines logo]()
$426
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/122:22 pm -
3 stops25h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![Multiple Airlines logo]()
$498
Find flight deals from Knoxville to Florence
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Florence (FLR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 20, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $744 (Delta) |
One-way from | $426 (American Airlines) |
Popular in | March |
Cheapest in | January |
Average price | $1,428 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 20, 2026.
Use the filters below to find and compare flights from Knoxville to Florence that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
KnoxvilleFlorence
TYS Knoxville McGhee Tyson - FLR Florence Peretola
TYSFLR
Knoxville McGhee Tyson
Mon 4/12
8:48 pm-10:20 pm
2 stops19h 32m
Florence Peretola
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$426
KnoxvilleFlorence
TYS Knoxville McGhee Tyson - FLR Florence Peretola
TYSFLR
Knoxville McGhee Tyson
Mon 4/12
2:22 pm-9:25 pm
3 stops25h 03m
Florence Peretola
Wed 12/31
12:00 am-6:00 pm
Nonstop0h 00m
$498
KnoxvilleFlorence
TYS Knoxville McGhee Tyson - FLR Florence Peretola
TYSFLR
Knoxville McGhee Tyson
Mon 1/18
7:20 pm-4:25 pm
2 stops15h 05m
Florence Peretola
Sat 1/23
12:20 pm-11:46 pm
2 stops17h 26m
$799
KnoxvilleFlorence
TYS Knoxville McGhee Tyson - FLR Florence Peretola
TYSFLR
Knoxville McGhee Tyson
Mon 1/18
12:20 pm-1:50 pm
2 stops19h 30m
Florence Peretola
Fri 1/22
9:50 am-11:59 pm
2 stops20h 09m
$815
KnoxvilleFlorence
TYS Knoxville McGhee Tyson - FLR Florence Peretola
TYSFLR
Knoxville McGhee Tyson
Sun 4/11
10:05 am-11:30 am
2 stops19h 25m
Florence Peretola
Tue 4/20
6:30 am-11:46 pm
2 stops23h 16m
$831
KnoxvilleFlorence
TYS Knoxville McGhee Tyson - FLR Florence Peretola
TYSFLR
Knoxville McGhee Tyson
Mon 11/30
1:55 pm-1:50 pm
2 stops17h 55m
Florence Peretola
Mon 12/7
1:10 pm-8:47 pm
2 stops37h 37m
$834
KnoxvilleFlorence
TYS Knoxville McGhee Tyson - FLR Florence Peretola
TYSFLR
Knoxville McGhee Tyson
Thu 1/14
2:04 pm-1:55 pm
2 stops17h 51m
Florence Peretola
Tue 1/19
9:50 am-11:59 pm
2 stops20h 09m
$877
KnoxvilleFlorence
TYS Knoxville McGhee Tyson - FLR Florence Peretola
TYSFLR
Knoxville McGhee Tyson
Thu 1/7
5:57 pm-4:25 pm
2 stops16h 28m
Florence Peretola
Tue 1/19
6:40 am-6:13 pm
2 stops17h 33m
$881
KnoxvilleFlorence
TYS Knoxville McGhee Tyson - FLR Florence Peretola
TYSFLR
Knoxville McGhee Tyson
Thu 1/14
2:04 pm-1:55 pm
2 stops17h 51m
Florence Peretola
Sun 1/24
9:50 am-11:59 pm
2 stops20h 09m
$927
KnoxvilleFlorence
TYS Knoxville McGhee Tyson - FLR Florence Peretola
TYSFLR
Knoxville McGhee Tyson
Wed 11/25
7:35 pm-8:15 pm
2 stops18h 40m
Florence Peretola
Sun 11/29
5:00 pm-11:59 pm
2 stops36h 59m
$1,088
Sorted by cheapest first
Compare providers for flights from Knoxville to Florence
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Florence in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-Florence flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Florence flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Florence flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Florence flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Florence flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Florence
Have a flexible travel schedule? Discover the best time to fly to Florence from Knoxville with our price prediction graph.
TYS-FLR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Florence
Reviews of airlines servicing Florence
Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated October 20, 2026.
Read through reviews of airlines operating flights from Knoxville to Florence, such as Delta and Lufthansa. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Food
7.2
Overall
7.8
Comfort
7.8
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Boarding
8.1
Food
7.2
Overall
7.8
Comfort
7.8
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Boarding
8.1
Food
7.2
Overall
7.8
Comfort
7.8
Crew
8.5
Entertainment
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Florence?
Book flights to Florence if you plan to visit one of these locationsPrato
Pistoia
Arezzo
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Complete your trip
Complete your trip to Florence by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Knoxville to Florence by cabin class
Find flights from Knoxville to Florence, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Florence
Explore flights to Florence departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 20, 2026.
Knoxville and Florence flights
Browse other Knoxville and Florence flight options. Last updated on October 20, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on October 20, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Knoxville to Florence
Discover the top 2 airlines that operate flights from Knoxville to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 20, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$759 | Average$1,105 | FlexibilityNo cancel fee | On-time76% | |
| Cheapest$836 | Average$1,203 | FlexibilityNo cancel fee | On-timeN/A |