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$489+ Cheap flights from Knoxville (TYS) to Florence (FLR)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/30. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — FLR
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from Knoxville to Florence

Best flights from Knoxville to Florence
Discover carefully curated flight deals from Knoxville to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 18, 2025.

This oojo deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/305:15 pmTYS - FLR
2 stops36h 30mBritish Airways
Fri 2/612:45 pmFLR - TYS
2 stops38h 11mBritish Airways
Deal found 12/16$489
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/315:00 pmTYS - FLR
2 stops20h 50mDelta
Sat 2/76:40 amFLR - TYS
2 stops20h 07mDelta
Deal found 12/17$499
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/3011:07 amTYS - FLR
2 stops19h 28mUnited Airlines
Tue 2/36:30 amFLR - TYS
2 stops38h 19mUnited Airlines
Deal found 12/16$500
This Brussels Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Brussels Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/312:25 pmTYS - FLR
3 stops38h 30mBrussels Airlines
Sat 2/76:35 amFLR - TYS
3 stops42h 52mBrussels Airlines
Deal found 12/17$644
This United Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/2311:07 amTYS - FLR
2 stops20h 28mUnited Airlines
Tue 1/276:30 amFLR - TYS
2 stops18h 57mUnited Airlines
Deal found 12/15$705
This FlightHub deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/74:00 pmTYS - FLR
2 stops21h 05mScandinavian Airlines
Sat 6/1312:20 pmFLR - TYS
2 stops39h 24mScandinavian Airlines
Deal found 12/16$1,430
This oojo deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/73:03 pmTYS - FLR
2 stops14h 27mBritish Airways
Sun 5/177:10 amFLR - TYS
2 stops19h 29mBritish Airways
Deal found 12/16$1,023
This Mytrip deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/3012:55 pmTYS - FLR
2 stops28h 10mMultiple Airlines
Fri 2/67:00 pmFLR - TYS
3 stops30h 27mMultiple Airlines
Deal found 12/16$2,177
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:00 amTYS - FLR
3 stops25h 05mUnited Airlines
Sun 5/176:30 amFLR - TYS
2 stops38h 38mUnited Airlines
Deal found 12/16$1,358

Find flight deals from Knoxville to Florence

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Florence (FLR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$489
(oojo)

Popular in

March

Cheapest in

October
Provider with most accurate pricing for Knoxville McGhee Tyson-Florence Peretola flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Florence Peretola flights.
Search Deals
From Knoxville McGhee Tyson to Florence Peretola
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($180 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($46 potential savings vs. average RT price).
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Knoxville to Florence that are best for you.

Fly from

Knoxville

Fly to

Florence

Route

Depart

Return

Price

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Fri 1/30

5:15 pm-11:45 am

2 stops36h 30m

Florence Peretola

Fri 2/6

12:45 pm-8:56 pm

2 stops38h 11m

$489

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Sat 1/31

5:00 pm-7:50 pm

2 stops20h 50m

Florence Peretola

Sat 2/7

6:40 am-8:47 pm

2 stops20h 07m

$499

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Fri 1/30

11:07 am-12:35 pm

2 stops19h 28m

Florence Peretola

Tue 2/3

6:30 am-2:49 pm

2 stops38h 19m

$500

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Sat 1/31

2:25 pm-10:55 am

3 stops38h 30m

Florence Peretola

Sat 2/7

6:35 am-7:27 pm

3 stops42h 52m

$644

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Fri 1/23

11:07 am-1:35 pm

2 stops20h 28m

Florence Peretola

Tue 1/27

6:30 am-7:27 pm

2 stops18h 57m

$705

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Thu 5/7

3:03 pm-11:30 am

2 stops14h 27m

Florence Peretola

Sun 5/17

7:10 am-8:39 pm

2 stops19h 29m

$1,023

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Thu 5/7

7:00 am-2:05 pm

3 stops25h 05m

Florence Peretola

Sun 5/17

6:30 am-3:08 pm

2 stops38h 38m

$1,358

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Sun 6/7

4:00 pm-7:05 pm

2 stops21h 05m

Florence Peretola

Sat 6/13

12:20 pm-9:44 pm

2 stops39h 24m

$1,430

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Fri 1/30

12:55 pm-11:05 pm

2 stops28h 10m

Florence Peretola

Fri 2/6

7:00 pm-7:27 pm

3 stops30h 27m

$2,177

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Sat 1/3

11:00 am-4:30 pm

2 stops23h 30m

$644

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 11 results
1
2

Compare providers for flights from Knoxville to Florence

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Florence in December.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*2 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Florence flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Knoxville-Florence flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Knoxville-Florence flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Florence flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Florence flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Florence

What is the cheapest time of day to fly from TYS to FLR?

Find hourly flight availability from Knoxville to Florence. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

One of the essential ways to save on airfare from Knoxville to Florence is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the afternoon could potentially save you up to 32% on airfare.

Reviews of airlines servicing Florence

Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated December 18, 2025.
Read through reviews of airlines operating flights from Knoxville to Florence, such as Delta, United Airlines, and Lufthansa. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,005 reviews

Comfort

7.9

Overall

7.9

Food

7.3

Boarding

8.1

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,005 reviews
Delta
7.9
Good
8,005 reviews

Comfort

7.9

Overall

7.9

Food

7.3

Boarding

8.1

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,090 reviews
Delta
7.9
Good
8,005 reviews

Comfort

7.9

Overall

7.9

Food

7.3

Boarding

8.1

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Lufthansa
6.8
Okay
7,634 reviews
Delta
7.9
Good
8,005 reviews

Comfort

7.9

Overall

7.9

Food

7.3

Boarding

8.1

Crew

8.5

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Florence?

    British Airways, Delta, and United Airlines can get you from Knoxville to Florence in just under 19h 28m. Your travel time can differ by up to 17h 02m. The distance between Knoxville and Florence is about 4791 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Knoxville to Florence round-trip?

    United Airlines, at $578, was found to be the cheapest airline from Knoxville to Florence.Alternate airlines to your destination round-trip include Lufthansa and Delta. United Airlines is priced at 54% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Knoxville to Florence that include hotel bookings?

    Yes. In addition to deals on Knoxville to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Florence.

  • Can I find deals for business class flights from Knoxville to Florence?

    Yes. Cheapflights offers flight deals from Knoxville to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Pistoia

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Top 3 airlines flying from Knoxville to Florence

Discover the top 3 airlines that operate flights from Knoxville to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
LufthansaCheapest$649Average$1,106FlexibilityNo cancel feeOn-time76%
United AirlinesCheapest$814Average$1,094FlexibilityNo cancel feeOn-time69%
DeltaCheapest$832Average$1,286FlexibilityNo cancel feeOn-timeN/A

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