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$548+ Cheap flights from Knoxville (TYS) to Florence (FLR)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/8. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — FLR
May 12 — May 191
Tue 5/12
Tue 5/19
1 adult, Economy
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Cheap flight deals from Knoxville to Florence

Cheapest flights from Knoxville to Florence
Explore the most affordable flight options available from Knoxville to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 12, 2026.

This oojo deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/211:45 pm
TYS
-
FLR
2 stops26h 35m
British Airways
Wed 11/412:10 pm
FLR
-
TYS
2 stops38h 54m
British Airways
Deal found 4/11$792
This United Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:35 pm
TYS
-
FLR
2 stops15h 00m
United Airlines
Wed 11/42:15 pm
FLR
-
TYS
2 stops39h 04m
United Airlines
Deal found 4/10$804
This United Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:15 am
TYS
-
FLR
2 stops27h 20m
United Airlines
Wed 9/306:30 am
FLR
-
TYS
2 stops24h 00m
United Airlines
Deal found 4/10$919
This United Airlines deal was found by Cheapflights users on 4/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:45 am
TYS
-
FLR
2 stops26h 25m
United Airlines
Wed 9/306:30 am
FLR
-
TYS
2 stops22h 49m
United Airlines
Deal found 4/11$954
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/87:18 pm
TYS
-
FLR
2 stops36h 52m
United Airlines
Mon 5/182:00 pm
FLR
-
TYS
2 stops50h 49m
United Airlines
Deal found 4/9$1,068
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:12 pm
TYS
-
FLR
2 stops22h 08m
Multiple Airlines
Sat 10/316:55 am
FLR
-
TYS
2 stops19h 09m
Multiple Airlines
Deal found 4/8$1,093

Find flight deals from Knoxville to Florence

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Florence (FLR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 12, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$919
(United Airlines)

One-way from

$548
(Kiwi.com)

Popular in

August

Cheapest in

January

Average price

$906
Provider with most accurate pricing for Knoxville McGhee Tyson-Florence Peretola flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Florence Peretola flights.
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From Knoxville McGhee Tyson to Florence Peretola
Search Deals
One-way flight from Knoxville McGhee Tyson to Florence Peretola
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($254 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 12% potential price decrease ($161 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 12, 2026.
Use the filters below to find and compare flights from Knoxville to Florence that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Tue 9/22

5:45 am-2:10 pm

2 stops26h 25m

Florence Peretola

Wed 9/30

6:30 am-11:19 pm

2 stops22h 49m

$954
Quickest round-trip

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Wed 9/23

10:00 am-4:35 pm

2 stops24h 35m

Florence Peretola

Wed 9/30

6:30 am-11:19 pm

2 stops22h 49m

$996

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Fri 5/8

7:18 pm-2:10 pm

2 stops36h 52m

Florence Peretola

Mon 5/18

6:30 am-11:44 pm

2 stops23h 14m

$1,152

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Thu 9/3

10:00 am-4:35 pm

2 stops24h 35m

Florence Peretola

Sat 9/19

6:30 am-2:37 pm

2 stops38h 07m

$1,152

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Fri 5/15

7:05 am-4:35 pm

2 stops27h 30m

Florence Peretola

Fri 5/22

6:30 am-8:56 pm

3 stops44h 26m

$1,398

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Tue 5/19

7:18 pm-6:30 pm

2 stops17h 12m

Florence Peretola

Sun 5/31

3:30 pm-8:34 pm

2 stops35h 04m

$1,505
Cheapest one-way

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Fri 5/8

7:10 am-10:55 pm

3 stops33h 45m

$594
Quickest one-way

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Tue 5/12

7:00 am-10:20 pm

2 stops33h 20m

$658

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/12

Sorted by cheapest first

Compare providers for flights from Knoxville to Florence

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Florence in April.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Florence flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Florence flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Florence flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Florence flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Florence flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Florence

How much does it cost to fly round-trip from Knoxville to Florence?

Reviews of airlines servicing Florence

Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated April 12, 2026.
Read through reviews of airlines operating flights from Knoxville to Florence, such as United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,574 reviews

Boarding

7.7

Entertainment

7.1

Crew

8.1

Food

6.6

Comfort

7.3

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family
United Airlines
7.4
Good
9,574 reviews
United Airlines
7.4
Good
9,574 reviews

Boarding

7.7

Entertainment

7.1

Crew

8.1

Food

6.6

Comfort

7.3

Overall

7.4

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

TYS - IAD

It was a short flight, so no time for amenities. Just glad everything was quick and easy from boarding to arriving at my destination with my family

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Knoxville to Florence?

    United Airlines can get you from Knoxville to Florence in just under 27h 20m. Your travel time can differ by up to . The distance between Knoxville and Florence is about 4791 mi.

  • What are the cheapest airlines flying from Knoxville to Florence round-trip?

    United Airlines, at $564, was found to be the cheapest airline from Knoxville to Florence. An alternate airline flying to your destination would be Lufthansa. United Airlines is priced at 61% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Knoxville to Florence that include hotel bookings?

    Yes. In addition to deals on Knoxville to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Florence.

  • Can I find deals for business class flights from Knoxville to Florence?

    Yes. Cheapflights offers flight deals from Knoxville to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Pistoia
Arezzo

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Knoxville to Florence

Discover the top 2 airlines that operate flights from Knoxville to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 12, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$564Average$1,094FlexibilityNo cancel feeOn-time69%
LufthansaCheapest$649Average$1,104FlexibilityNo cancel feeOn-time76%

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