Florence

$589+ Cheap flights from Des Moines (DSM) to Florence (FLR)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/28. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — FLR
Aug 21 — Aug 281
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Cheap flight deals from Des Moines to Florence

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Florence (FLR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 16, 2025.

Round-trip from

$693
(Delta)

One-way from

$589
(British Airways)
From Des Moines to Florence Peretola
One-way flight from Des Moines to Florence Peretola

Find flight deals from Des Moines to Florence

Cheapest flights from Des Moines to Florence
Explore the most affordable flight options available from Des Moines to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 16, 2025.

This Delta deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/142:14 pmDSM - FLR
2 stops22h 36mDelta
Tue 11/186:50 amFLR - DSM
2 stops21h 00mDelta
Deal found 8/15$693
This Ovago deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/304:25 pmDSM - FLR
2 stops22h 55mBritish Airways
Tue 10/77:05 amFLR - DSM
2 stops20h 06mBritish Airways
Deal found 8/16$774
This Surpr!ce deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Surpr!ce is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2910:20 amDSM - FLR
2 stops18h 00mKLM
Mon 10/68:30 pmFLR - DSM
2 stops27h 21mKLM
Deal found 8/15$810
This British Airways deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/292:21 pmDSM - FLR
2 stops24h 59mBritish Airways
Mon 10/67:05 amFLR - DSM
2 stops20h 06mBritish Airways
Deal found 8/15$840
This Trip.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2810:55 amDSM - FLR
2 stops17h 25mAir France
Sun 10/56:25 amFLR - DSM
2 stops18h 20mAir France
Deal found 8/14$873
This Orbitz deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/304:25 pmDSM - FLR
2 stops22h 55mBritish Airways
Mon 10/67:05 amFLR - DSM
2 stops20h 06mBritish Airways
Deal found 8/14$889
This Expedia deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/286:09 pmDSM - FLR
2 stops42h 26mIberia
Sun 10/58:20 pmFLR - DSM
2 stops34h 03mIberia
Deal found 8/14$901
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/285:54 pmDSM - FLR
2 stops16h 26mDelta
Sun 10/56:30 amFLR - DSM
2 stops21h 00mDelta
Deal found 8/14$989
This Air Canada deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/3011:31 amDSM - FLR
3 stops18h 29mAir Canada
Tue 10/76:40 amFLR - DSM
3 stops22h 10mAir Canada
Deal found 8/16$1,136
This Air Canada deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/3011:31 amDSM - FLR
3 stops18h 29mAir Canada
Mon 10/66:40 amFLR - DSM
3 stops22h 10mAir Canada
Deal found 8/14$1,202
This Mytrip deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/298:25 amDSM - FLR
3 stops31h 30mMultiple Airlines
Mon 10/66:45 pmFLR - DSM
3 stops35h 38mMultiple Airlines
Deal found 8/15$1,365

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 16, 2025.
Use the filters below to find and compare flights from Des Moines to Florence that are best for you.

Fly from

Des Moines

Fly to

Florence

Route

Depart

Return

Price

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Fri 11/14

6:30 pm-7:50 pm

2 stops18h 20m

Florence Peretola

Tue 11/18

9:50 am-10:23 pm

2 stops19h 33m

$693

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Tue 9/30

4:25 pm-10:20 pm

2 stops22h 55m

Florence Peretola

Tue 10/7

7:05 am-8:11 pm

2 stops20h 06m

$774

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Mon 9/29

10:20 am-11:20 am

2 stops18h 00m

Florence Peretola

Mon 10/6

8:30 pm-4:51 pm

2 stops27h 21m

$810

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Mon 9/29

2:21 pm-10:20 pm

2 stops24h 59m

Florence Peretola

Mon 10/6

7:05 am-8:11 pm

2 stops20h 06m

$840

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Sun 9/28

10:55 am-11:20 am

2 stops17h 25m

Florence Peretola

Sun 10/5

6:25 am-5:45 pm

2 stops18h 20m

$873

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Tue 9/30

4:25 pm-10:20 pm

2 stops22h 55m

Florence Peretola

Mon 10/6

7:05 am-8:11 pm

2 stops20h 06m

$889

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Sun 9/28

6:09 pm-7:35 pm

2 stops42h 26m

Florence Peretola

Sun 10/5

8:20 pm-11:23 pm

2 stops34h 03m

$901

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Sun 9/28

5:54 pm-5:20 pm

2 stops16h 26m

Florence Peretola

Sun 10/5

6:30 am-8:30 pm

2 stops21h 00m

$989

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Sun 9/28

6:09 pm-10:20 pm

2 stops21h 11m

$589

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Sun 9/28

1:00 pm-2:05 pm

3 stops18h 05m

$612

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/14

Best time to book a flight from Des Moines to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Florence

Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated August 16, 2025.
See what other customers who have flown with Delta, United Airlines, and Lufthansa from Des Moines to Florence have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good
8.0
Very good

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Boarding

8.2

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What are the cheapest airlines flying from Des Moines to Florence round-trip?

    Flying on United Airlines is currently your cheapest option to Florence, with prices starting at $790. Additional round-trip tickets that might be worth considering are offered by Lufthansa and Delta, with the lowest prices starting at $811 and $955, respectively.

  • Can I find deals for flights from Des Moines to Florence that include hotel bookings?

    Yes. In addition to deals on Des Moines to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Florence.

  • Can I find deals for business class flights from Des Moines to Florence?

    Yes. Cheapflights offers flight deals from Des Moines to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Florence?

    Currently, November is the cheapest month in which you can book a flight from Des Moines to Florence (average of $766). Flying from Des Moines to Florence in June is currently the most expensive (average of $1,296). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Des Moines to Florence

Discover the top 3 airlines that operate flights from Des Moines to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$790Average$1,186FlexibilityNo cancel feeOn-time69%
LufthansaCheapest$811Average$1,367FlexibilityNo cancel feeOn-time76%
DeltaCheapest$955Average$1,517FlexibilityNo cancel feeOn-timeN/A

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