How long is the flight from Des Moines to Florence?

Airlines like Lufthansa fly from Des Moines to Florence in about 14h 42m. The time it takes to get you to your destination can typically vary by up to . Des Moines and Florence are separated by a distance of 4923 mi.

What are the cheapest airlines flying from Des Moines to Florence round-trip?

Flying on Lufthansa is currently your cheapest option to Florence, with prices starting at $738. Additional round-trip tickets that might be worth considering are offered by United Airlines and Delta, with the lowest prices starting at $790 and $923, respectively. Lufthansa is priced at 39% lower than the current average price of a flight leaving 3 months from now.

In terms of precipitation, rainfall in Florence ranges from 1.2 - 3.9 inches per month. October is typically the wettest month, when rainfall can reach 3.9 in. July is typically the driest time to visit Florence when rainfall is around 1.2 in.

If weather is an important factor for your trip to Florence, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

What are the most popular airlines that fly from Des Moines to Florence?

When booking a flight from Des Moines to Florence, you may want to consider flying on United Airlines, Delta or Lufthansa as they are the most popular for this route.

What is the cheapest time of day to fly from DSM to FLR?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Florence as you normally would.

Most accurate provider : When it comes to deals on Des Moines-Florence flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Des Moines-Florence flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Des Moines-Florence flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Des Moines-Florence flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Florence flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Des Moines to Florence that include hotel bookings?

Yes. In addition to deals on Des Moines to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Des Moines to Florence?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Florence.

Can I find deals for business class flights from Des Moines to Florence?

Yes. Cheapflights offers flight deals from Des Moines to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$373+ Flights from Des Moines to Florence

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Cheap flight deals from Des Moines to Florence

Cheapest flights from Des Moines to Florence
Explore the most affordable flight options available from Des Moines to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Tue 12/236:46 pmDSM - FLR

2 stops42h 54mMultiple Airlines

Thu 1/16:35 amFLR - DSM

2 stops18h 30mMultiple Airlines

Deal found 12/16

$1,744

Tue 12/236:46 pmDSM - FLR

2 stops38h 44mLufthansa

Thu 1/16:35 amFLR - DSM

2 stops22h 05mLufthansa

Deal found 12/17

$1,816

Tue 12/2311:35 amDSM - FLR

3 stops19h 40mAir Canada

Thu 1/16:35 amFLR - DSM

3 stops18h 30mAir Canada

Deal found 12/17

$4,525

Best flights from Des Moines to Florence
Discover carefully curated flight deals from Des Moines to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 18, 2025.

Fri 1/3011:30 amDSM - FLR

2 stops18h 05mMultiple Airlines

Fri 2/66:30 amFLR - DSM

2 stops22h 20mMultiple Airlines

Deal found 12/16

$471

Fri 1/306:48 pmDSM - FLR

2 stops14h 42mLufthansa

Fri 2/66:30 amFLR - DSM

2 stops22h 20mLufthansa

Deal found 12/16

$476

Sat 1/3110:59 amDSM - FLR

2 stops17h 26mDelta

Sat 2/76:40 amFLR - DSM

2 stops21h 44mDelta

Deal found 12/17

$499

Tue 2/106:48 pmDSM - FLR

2 stops20h 12mLufthansa

Tue 2/246:30 amFLR - DSM

2 stops22h 11mLufthansa

Deal found 12/17

$480

Tue 3/312:25 pmDSM - FLR

2 stops24h 25mDelta

Tue 3/106:40 amFLR - DSM

2 stops20h 35mDelta

Deal found 12/16

$499

Wed 2/1111:30 amDSM - FLR

2 stops22h 00mLufthansa

Wed 2/256:30 amFLR - DSM

2 stops22h 11mLufthansa

Deal found 12/16

$480

Mon 3/210:57 amDSM - FLR

2 stops17h 28mDelta

Mon 3/166:40 amFLR - DSM

2 stops33h 59mDelta

Deal found 12/16

$499

Sat 1/316:48 pmDSM - FLR

2 stops18h 47mLufthansa

Sat 2/76:30 amFLR - DSM

2 stops22h 20mLufthansa

Deal found 12/17

$492

Mon 3/26:19 amDSM - FLR

2 stops30h 31mDelta

Thu 3/126:40 amFLR - DSM

2 stops32h 55mDelta

Deal found 12/16

$499

Tue 3/310:57 amDSM - FLR

2 stops25h 53mDelta

Wed 3/116:40 amFLR - DSM

2 stops33h 42mDelta

Deal found 12/16

$499

Last-minute flights from Des Moines to Florence
Discover last-minute flight deals from Des Moines to Florence. Data last updated December 18, 2025 and is based on user searches.

Thu 1/296:48 pmDSM - FLR

2 stops34h 47mUnited Airlines

Mon 2/26:30 amFLR - DSM

2 stops39h 03mUnited Airlines

Deal found 12/16

$500

Fri 1/3011:30 amDSM - FLR

2 stops18h 05mMultiple Airlines

Fri 2/66:30 amFLR - DSM

2 stops22h 20mMultiple Airlines

Deal found 12/16

$471

Fri 1/306:48 pmDSM - FLR

2 stops14h 42mLufthansa

Fri 2/66:30 amFLR - DSM

2 stops22h 20mLufthansa

Deal found 12/16

$476

Fri 1/305:01 pmDSM - FLR

2 stops35h 44mBritish Airways

Fri 2/612:45 pmFLR - DSM

2 stops39h 19mBritish Airways

Deal found 12/16

$489

Sat 1/3110:59 amDSM - FLR

2 stops17h 26mDelta

Sat 2/76:40 amFLR - DSM

2 stops21h 44mDelta

Deal found 12/17

$499

Sat 1/3111:30 amDSM - FLR

3 stops27h 45mMultiple Airlines

Sat 2/76:30 amFLR - DSM

2 stops22h 20mMultiple Airlines

Deal found 12/16

$710

Sat 1/317:50 amDSM - FLR

3 stops22h 45mAir Canada

Sat 2/78:00 amFLR - DSM

3 stops20h 50mAir Canada

Deal found 12/16

$715

One-way flights from Des Moines to Florence
Search for one-way flight options from Des Moines to Florence. Find affordable one-way fares based on user searches. Data last updated December 18, 2025.

Thu 1/156:48 pmDSM - FLR

2 stops18h 52mLufthansa

Deal found 12/16

$373

Thu 1/154:30 pmDSM - FLR

3 stops59h 25mMultiple Airlines

Deal found 12/16

$481

Fri 6/511:30 amDSM - FLR

2 stops18h 10mLufthansa

Deal found 12/17

$1,043

Fri 6/56:25 amDSM - FLR

3 stops27h 15mUnited Airlines

Deal found 12/16

$1,116

Find flight deals from Des Moines to Florence

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$471 (Billigflug)
One-way from	$373 (Kiwi.com)
Popular in	June
Cheapest in	October
Average price	$1,472

Provider with most accurate pricing for Des Moines-Florence Peretola flight deals.

Search Deals

Provider most trusted by Cheapflights users for Des Moines-Florence Peretola flights.

Search Deals

From Des Moines to Florence Peretola

Search Deals

One-way flight from Des Moines to Florence Peretola

Search Deals

Highest demand for flights based on searches. 16% potential increase in price ($247 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 4% potential price decrease ($49 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Florence that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Fri 1/30

11:30 am-12:35 pm

2 stops18h 05m

Florence Peretola

Fri 2/6

6:30 am-9:50 pm

2 stops22h 20m

$471

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Fri 1/30

6:48 pm-4:30 pm

2 stops14h 42m

Florence Peretola

Fri 2/6

6:30 am-9:50 pm

2 stops22h 20m

$476

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Tue 2/10

6:48 pm-10:00 pm

2 stops20h 12m

Florence Peretola

Tue 2/24

6:30 am-9:41 pm

2 stops22h 11m

$480

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Wed 2/11

11:30 am-4:30 pm

2 stops22h 00m

Florence Peretola

Wed 2/25

6:30 am-9:41 pm

2 stops22h 11m

$480

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Sat 1/31

6:48 pm-8:35 pm

2 stops18h 47m

Florence Peretola

Sat 2/7

6:30 am-9:50 pm

2 stops22h 20m

$492

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Sat 1/31

10:59 am-11:25 am

2 stops17h 26m

Florence Peretola

Sat 2/7

6:40 am-9:24 pm

2 stops21h 44m

$499

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Tue 3/3

12:25 pm-7:50 pm

2 stops24h 25m

Florence Peretola

Tue 3/10

6:40 am-9:15 pm

2 stops20h 35m

$499

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Mon 3/2

10:57 am-11:25 am

2 stops17h 28m

Florence Peretola

Mon 3/16

6:40 am-10:39 am

2 stops33h 59m

$499

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Mon 3/2

6:19 am-7:50 pm

2 stops30h 31m

Florence Peretola

Thu 3/12

6:40 am-9:35 am

2 stops32h 55m

$499

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Tue 3/3

10:57 am-7:50 pm

2 stops25h 53m

Florence Peretola

Wed 3/11

6:40 am-10:22 am

2 stops33h 42m

$499

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 14 results

Compare providers for flights from Des Moines to Florence

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Florence in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars
AranGrant	Price Accuracy2 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Des Moines-Florence flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Des Moines-Florence flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Des Moines-Florence flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Des Moines-Florence flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Florence flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Des Moines with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Florence

See what other customers who have flown with Delta, United Airlines, and Lufthansa from Des Moines to Florence have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.9

Good

8,008 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Delta

7.9

Good

8,008 reviews

Delta

7.9

Good

8,008 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

United Airlines

7.4

Good

9,093 reviews

Delta

7.9

Good

8,008 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

Lufthansa

6.8

Okay

7,635 reviews

Delta

7.9

Good

8,008 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

Related info for your journey

How long is the flight from Des Moines to Florence?
Airlines like Lufthansa fly from Des Moines to Florence in about 14h 42m. The time it takes to get you to your destination can typically vary by up to . Des Moines and Florence are separated by a distance of 4923 mi.
What are the cheapest airlines flying from Des Moines to Florence round-trip?
Flying on Lufthansa is currently your cheapest option to Florence, with prices starting at $738. Additional round-trip tickets that might be worth considering are offered by United Airlines and Delta, with the lowest prices starting at $790 and $923, respectively. Lufthansa is priced at 39% lower than the current average price of a flight leaving 3 months from now.
Can I find deals for flights from Des Moines to Florence that include hotel bookings?
Yes. In addition to deals on Des Moines to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Des Moines to Florence?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Florence.
Can I find deals for business class flights from Des Moines to Florence?
Yes. Cheapflights offers flight deals from Des Moines to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Pistoia

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Top 3 airlines flying from Des Moines to Florence

Airline	Cheapest	Average	Flexibility	On-time
Lufthansa	Cheapest$738	Average$1,185	FlexibilityNo cancel fee	On-time76%
United Airlines	Cheapest$790	Average$1,308	FlexibilityNo cancel fee	On-time69%
Delta	Cheapest$923	Average$1,519	FlexibilityNo cancel fee	On-timeN/A

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$373+ Cheap flights from Des Moines (DSM) to Florence (FLR)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/15. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Des Moines to Florence with Cheapflights

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2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Des Moines to Florence

Cheapest flights from Des Moines to FlorenceExplore the most affordable flight options available from Des Moines to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Explore the most affordable flight options available from Des Moines to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Find flight deals from Des Moines to Florence

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Florence that are best for you.

Compare providers for flights from Des Moines to Florence

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Florence in December.

Best time to book a flight from Des Moines to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Des Moines with our price prediction graph.

Reviews of airlines servicing Florence

See what other customers who have flown with Delta, United Airlines, and Lufthansa from Des Moines to Florence have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Des Moines to Florence?

What are the cheapest airlines flying from Des Moines to Florence round-trip?

Can I find deals for flights from Des Moines to Florence that include hotel bookings?

How can I find direct flights from Des Moines to Florence?

Can I find deals for business class flights from Des Moines to Florence?

Traveling to a place near Florence?

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Alternative routes for Des Moines to Florence

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Top 3 airlines flying from Des Moines to Florence

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Cheapest flights from Des Moines to Florence
Explore the most affordable flight options available from Des Moines to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.