How long is the flight from Des Moines to Florence?

Airlines like Lufthansa fly from Des Moines to Florence in about 14h 42m. The time it takes to get you to your destination can typically vary by up to . Des Moines and Florence are separated by a distance of 4923 mi.

What are the cheapest airlines flying from Des Moines to Florence round-trip?

Flying on Lufthansa is currently your cheapest option to Florence, with prices starting at $738. Additional round-trip tickets that might be worth considering are offered by United Airlines and Delta, with the lowest prices starting at $790 and $923, respectively. Lufthansa is priced at 39% lower than the current average price of a flight leaving 3 months from now.

In terms of precipitation, rainfall in Florence ranges from 1.2 - 3.9 inches per month. October is typically the wettest month, when rainfall can reach 3.9 in. July is typically the driest time to visit Florence when rainfall is around 1.2 in.

If weather is an important factor for your trip to Florence, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

What are the most popular airlines that fly from Des Moines to Florence?

When booking a flight from Des Moines to Florence, you may want to consider flying on United Airlines, Delta or Lufthansa as they are the most popular for this route.

What is the cheapest time of day to fly from DSM to FLR?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Des Moines to Florence as you normally would.

Most accurate provider : When it comes to deals on Des Moines-Florence flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Des Moines-Florence flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Des Moines-Florence flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Des Moines-Florence flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Florence flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Des Moines to Florence that include hotel bookings?

Yes. In addition to deals on Des Moines to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Des Moines to Florence?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Florence.

Can I find deals for business class flights from Des Moines to Florence?

Yes. Cheapflights offers flight deals from Des Moines to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$459+ Flights from Des Moines to Florence

Q: How much does it cost to fly round-trip from Des Moines to Florence?

Airfare is below average for this route at the moment. Des Moines to Florence flights typically cost between $1,457 and $1,483 in January. The cheapest round-trip price found within the last 3 days was $459 on Lufthansa (Jan 22-Jan 29).

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Cheap flight deals from Des Moines to Florence

Cheapest flights from Des Moines to Florence
Explore the most affordable flight options available from Des Moines to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 9, 2025.

mar. 12/236:46 pmDSM - FLR

2 stops34h 49mUnited Airlines

jue. 1/19:45 amFLR - DSM

2 stops32h 05mUnited Airlines

Deal found 12/7

$1,385

mar. 12/236:46 pmDSM - FLR

2 stops34h 49mLufthansa

jue. 1/15:15 pmFLR - DSM

2 stops35h 25mLufthansa

Deal found 12/8

$1,850

Best flights from Des Moines to Florence
Discover carefully curated flight deals from Des Moines to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated diciembre 9, 2025.

jue. 1/226:48 pmDSM - FLR

2 stops14h 42mLufthansa

jue. 1/296:35 amFLR - DSM

2 stops18h 12mLufthansa

Deal found 12/8

$459

jue. 1/2211:30 amDSM - FLR

2 stops18h 05mMultiple Airlines

jue. 1/296:35 amFLR - DSM

2 stops22h 15mMultiple Airlines

Deal found 12/8

$470

vie. 1/2310:59 amDSM - FLR

2 stops17h 21mKLM

vie. 1/306:40 amFLR - DSM

2 stops17h 28mKLM

Deal found 12/8

$490

jue. 1/299:03 amDSM - FLR

2 stops20h 32mUnited Airlines

lun. 2/26:30 amFLR - DSM

2 stops24h 14mUnited Airlines

Deal found 12/6

$500

mié. 1/2111:30 amDSM - FLR

2 stops26h 10mMultiple Airlines

mié. 1/286:30 amFLR - DSM

2 stops22h 20mMultiple Airlines

Deal found 12/8

$485

mié. 1/216:48 pmDSM - FLR

2 stops18h 52mLufthansa

mié. 1/286:30 amFLR - DSM

2 stops22h 20mLufthansa

Deal found 12/7

$490

jue. 1/2211:26 amDSM - FLR

2 stops14h 29mKLM

jue. 1/296:40 amFLR - DSM

2 stops21h 14mKLM

Deal found 12/7

$499

mar. 1/206:48 pmDSM - FLR

2 stops20h 12mLufthansa

mar. 1/271:15 pmFLR - DSM

2 stops15h 35mLufthansa

Deal found 12/8

$492

Last-minute flights from Des Moines to Florence
Discover last-minute flight deals from Des Moines to Florence. Data last updated diciembre 9, 2025 and is based on user searches.

mar. 1/206:48 pmDSM - FLR

2 stops20h 12mLufthansa

mar. 1/276:30 amFLR - DSM

2 stops22h 20mLufthansa

Deal found 12/7

$478

mié. 1/2111:30 amDSM - FLR

2 stops26h 10mMultiple Airlines

mié. 1/286:30 amFLR - DSM

2 stops22h 20mMultiple Airlines

Deal found 12/8

$485

mié. 1/216:48 pmDSM - FLR

2 stops18h 52mLufthansa

mié. 1/286:30 amFLR - DSM

2 stops22h 20mLufthansa

Deal found 12/7

$489

jue. 1/226:48 pmDSM - FLR

2 stops14h 42mLufthansa

jue. 1/296:35 amFLR - DSM

2 stops18h 12mLufthansa

Deal found 12/8

$459

jue. 1/2211:30 amDSM - FLR

2 stops18h 05mMultiple Airlines

jue. 1/296:35 amFLR - DSM

2 stops22h 15mMultiple Airlines

Deal found 12/8

$470

jue. 1/2211:26 amDSM - FLR

2 stops14h 29mKLM

jue. 1/296:40 amFLR - DSM

2 stops21h 14mKLM

Deal found 12/7

$499

vie. 1/2310:59 amDSM - FLR

2 stops17h 21mKLM

vie. 1/306:40 amFLR - DSM

2 stops17h 28mKLM

Deal found 12/8

$491

Find flight deals from Des Moines to Florence

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$459 (Ticket)
Popular in	June
Cheapest in	October
Average price	$1,472

Provider with most accurate pricing for Des Moines-Florence Peretola flight deals.

Search Deals

Provider most trusted by Cheapflights users for Des Moines-Florence Peretola flights.

Search Deals

From Des Moines to Florence Peretola

Search Deals

Highest demand for flights based on searches. 16% potential increase in price ($247 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 4% potential price decrease ($49 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Florence that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

jue. 1/22

6:48 pm-4:30 pm

2 stops14h 42m

Florence Peretola

jue. 1/29

6:35 am-5:47 pm

2 stops18h 12m

$459

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

jue. 1/22

11:30 am-12:35 pm

2 stops18h 05m

Florence Peretola

jue. 1/29

6:35 am-9:50 pm

2 stops22h 15m

$470

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

mié. 1/21

11:30 am-8:40 pm

2 stops26h 10m

Florence Peretola

mié. 1/28

6:30 am-9:50 pm

2 stops22h 20m

$485

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

vie. 1/23

10:59 am-11:20 am

2 stops17h 21m

Florence Peretola

vie. 1/30

6:40 am-5:08 pm

2 stops17h 28m

$490

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

mié. 1/21

6:48 pm-8:40 pm

2 stops18h 52m

Florence Peretola

mié. 1/28

6:30 am-9:50 pm

2 stops22h 20m

$490

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

mar. 1/20

6:48 pm-10:00 pm

2 stops20h 12m

Florence Peretola

mar. 1/27

1:15 pm-9:50 pm

2 stops15h 35m

$492

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

jue. 1/22

11:26 am-8:55 am

2 stops14h 29m

Florence Peretola

jue. 1/29

6:40 am-8:54 pm

2 stops21h 14m

$499

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

jue. 1/29

9:03 am-12:35 pm

2 stops20h 32m

Florence Peretola

lun. 2/2

6:30 am-11:44 pm

2 stops24h 14m

$500

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/8

Compare providers for flights from Des Moines to Florence

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Florence in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
AranGrant	Price Accuracy2 stars	Trust Score*3 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Des Moines-Florence flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Des Moines-Florence flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Des Moines-Florence flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Des Moines-Florence flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Florence flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Des Moines with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Florence

How much does it cost to fly round-trip from Des Moines to Florence?

Reviews of airlines servicing Florence

See what other customers who have flown with Delta, United Airlines, and Lufthansa from Des Moines to Florence have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.9

Good

8,007 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Delta

7.9

Good

8,007 reviews

Delta

7.9

Good

8,007 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

United Airlines

7.4

Good

9,092 reviews

Delta

7.9

Good

8,007 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

Lufthansa

6.8

Okay

7,619 reviews

Delta

7.9

Good

8,007 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

Related info for your journey

How long is the flight from Des Moines to Florence?
Airlines like Lufthansa fly from Des Moines to Florence in about 14h 42m. The time it takes to get you to your destination can typically vary by up to . Des Moines and Florence are separated by a distance of 4923 mi.
What are the cheapest airlines flying from Des Moines to Florence round-trip?
Flying on Lufthansa is currently your cheapest option to Florence, with prices starting at $738. Additional round-trip tickets that might be worth considering are offered by United Airlines and Delta, with the lowest prices starting at $790 and $923, respectively. Lufthansa is priced at 39% lower than the current average price of a flight leaving 3 months from now.
Can I find deals for flights from Des Moines to Florence that include hotel bookings?
Yes. In addition to deals on Des Moines to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Des Moines to Florence?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Florence.
Can I find deals for business class flights from Des Moines to Florence?
Yes. Cheapflights offers flight deals from Des Moines to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Pistoia

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Top 3 airlines flying from Des Moines to Florence

Airline	Cheapest	Average	Flexibility	On-time
Lufthansa	Cheapest$738	Average$1,185	FlexibilityNo cancel fee	On-time76%
United Airlines	Cheapest$790	Average$1,308	FlexibilityNo cancel fee	On-time69%
Delta	Cheapest$923	Average$1,519	FlexibilityNo cancel fee	On-timeN/A

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$459+ Cheap flights from Des Moines (DSM) to Florence (FLR)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/22. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Des Moines to Florence with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Des Moines to Florence

Cheapest flights from Des Moines to FlorenceExplore the most affordable flight options available from Des Moines to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 9, 2025.

Explore the most affordable flight options available from Des Moines to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 9, 2025.

Find flight deals from Des Moines to Florence

Most accurate provider

Most trusted provider

Round-trip from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Florence that are best for you.

Compare providers for flights from Des Moines to Florence

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Florence in December.

Best time to book a flight from Des Moines to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Des Moines with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Florence

How much does it cost to fly round-trip from Des Moines to Florence?

Reviews of airlines servicing Florence

See what other customers who have flown with Delta, United Airlines, and Lufthansa from Des Moines to Florence have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Des Moines to Florence?

What are the cheapest airlines flying from Des Moines to Florence round-trip?

Can I find deals for flights from Des Moines to Florence that include hotel bookings?

How can I find direct flights from Des Moines to Florence?

Can I find deals for business class flights from Des Moines to Florence?

Traveling to a place near Florence?

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Alternative routes for Des Moines to Florence

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Top 3 airlines flying from Des Moines to Florence

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Cheapest flights from Des Moines to Florence
Explore the most affordable flight options available from Des Moines to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 9, 2025.