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$439+ Cheap flights from Des Moines (DSM) to Florence (FLR)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — FLR
Feb 19 — Feb 261
Thu 2/19
Thu 2/26
1 adult, Economy
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Cheap flight deals from Des Moines to Florence

Cheapest flights from Des Moines to Florence
Explore the most affordable flight options available from Des Moines to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 20, 2026.

This oojo deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:18 pm
DSM
-
FLR
2 stops25h 02m
British Airways
Wed 4/227:05 am
FLR
-
DSM
2 stops19h 26m
British Airways
Deal found 1/18$439
This Iberia deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/21:38 pm
DSM
-
FLR
2 stops17h 37m
Multiple Airlines
Mon 3/911:30 am
FLR
-
DSM
2 stops41h 04m
Multiple Airlines
Deal found 1/19$461
This Iberia deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/310:04 am
DSM
-
FLR
2 stops29h 56m
Iberia
Tue 3/106:55 am
FLR
-
DSM
2 stops21h 39m
Iberia
Deal found 1/19$465
This Cheapflightsfares deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/106:48 pm
DSM
-
FLR
2 stops14h 42m
Lufthansa
Tue 2/246:30 am
FLR
-
DSM
2 stops18h 17m
Lufthansa
Deal found 1/18$482
This United Airlines deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/113:35 pm
DSM
-
FLR
2 stops14h 00m
United Airlines
Wed 2/256:30 am
FLR
-
DSM
2 stops22h 50m
United Airlines
Deal found 1/20$500
This United Airlines deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/43:24 pm
DSM
-
FLR
2 stops18h 06m
United Airlines
Wed 3/116:30 am
FLR
-
DSM
3 stops39h 37m
United Airlines
Deal found 1/18$511
This lastminute.com deal was found by Cheapflights users on 1/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/46:55 pm
DSM
-
FLR
2 stops20h 20m
Lufthansa
Wed 3/111:15 pm
FLR
-
DSM
2 stops34h 53m
Lufthansa
Deal found 1/18$513

Find flight deals from Des Moines to Florence

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Florence (FLR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 20, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$439
(oojo)

Popular in

June

Cheapest in

April

Average price

$923
Provider with most accurate pricing for Des Moines-Florence Peretola flight deals.
Search Deals
Provider most trusted by Cheapflights users for Des Moines-Florence Peretola flights.
Search Deals
From Des Moines to Florence Peretola
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($256 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($58 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 20, 2026.
Use the filters below to find and compare flights from Des Moines to Florence that are best for you.

Fly from

Des Moines

Fly to

Florence

Route

Depart

Return

Price

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Mon 3/2

1:38 pm-2:15 pm

2 stops17h 37m

Florence Peretola

Mon 3/9

11:30 am-10:34 pm

2 stops41h 04m

$461

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Tue 3/3

10:04 am-11:00 pm

2 stops29h 56m

Florence Peretola

Tue 3/10

6:55 am-10:34 pm

2 stops21h 39m

$465

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Thu 2/19

10:36 am-2:25 pm

2 stops20h 49m

Florence Peretola

Thu 2/26

6:40 am-3:40 pm

2 stops16h 00m

$500

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Wed 3/4

3:24 pm-4:30 pm

2 stops18h 06m

Florence Peretola

Wed 3/11

6:30 am-4:07 pm

2 stops39h 37m

$501

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Wed 2/11

11:30 am-12:35 pm

2 stops18h 05m

Florence Peretola

Wed 2/25

6:30 am-8:07 pm

2 stops20h 37m

$501

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Wed 3/4

6:55 pm-10:15 pm

2 stops20h 20m

Florence Peretola

Wed 3/11

1:15 pm-6:08 pm

2 stops34h 53m

$513

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Fri 6/5

1:45 pm-10:20 pm

2 stops25h 35m

$1,090

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Fri 6/5

6:15 am-10:40 am

3 stops21h 25m

$3,244

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Compare providers for flights from Des Moines to Florence

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Florence in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
AranGrantPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Florence flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Florence flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Florence flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Florence flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Florence flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Florence

Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated January 20, 2026.
See what other customers who have flown with Delta and United Airlines from Des Moines to Florence have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,080 reviews

Comfort

7.9

Boarding

8.1

Food

7.2

Entertainment

7.8

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,080 reviews
Delta
7.9
Good
8,080 reviews

Comfort

7.9

Boarding

8.1

Food

7.2

Entertainment

7.8

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,183 reviews
Delta
7.9
Good
8,080 reviews

Comfort

7.9

Boarding

8.1

Food

7.2

Entertainment

7.8

Crew

8.5

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Florence?

    Airlines like Iberia and Delta fly from Des Moines to Florence in about 20h 49m. The time it takes to get you to your destination can typically vary by up to 9h 07m. Des Moines and Florence are separated by a distance of 4923 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Des Moines to Florence round-trip?

    Flying on United Airlines is currently your cheapest option to Florence, with prices starting at $504. Another option worth looking into is Delta, starting at $505 round trip. United Airlines is priced at 56% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Des Moines to Florence that include hotel bookings?

    Yes. In addition to deals on Des Moines to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Florence.

  • Can I find deals for business class flights from Des Moines to Florence?

    Yes. Cheapflights offers flight deals from Des Moines to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Pistoia

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Top 2 airlines flying from Des Moines to Florence

Discover the top 2 airlines that operate flights from Des Moines to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 20, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$504Average$1,195FlexibilityNo cancel feeOn-time69%
DeltaCheapest$505Average$1,668FlexibilityNo cancel feeOn-timeN/A

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