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$848+ Cheap flights from Des Moines (DSM) to Florence (FLR)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/9. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — FLR
Dec 10 — Dec 171
Wed 12/10
Wed 12/17
1 adult, Economy
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Cheap flight deals from Des Moines to Florence

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Florence (FLR). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 10, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$848
(United Airlines)

Popular in

June

Cheapest in

October

Average price

$1,372
Provider with most accurate pricing for Des Moines-Florence Peretola flight deals.
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Provider most trusted by Cheapflights users for Des Moines-Florence Peretola flights.
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From Des Moines to Florence Peretola
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Highest demand for flights based on searches. 15% potential increase in price ($234 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($43 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Des Moines to Florence

Cheapest flights from Des Moines to Florence
Explore the most affordable flight options available from Des Moines to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 10, 2025.

This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:46 pmDSM - FLR
2 stops34h 49mUnited Airlines
Tue 12/306:30 amFLR - DSM
2 stops24h 28mUnited Airlines
Deal found 11/7$1,053
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/243:14 pmDSM - FLR
2 stops14h 21mUnited Airlines
Wed 12/319:35 amFLR - DSM
2 stops19h 05mUnited Airlines
Deal found 11/9$1,202
This Kissandfly.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kissandfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/243:14 pmDSM - FLR
2 stops14h 21mLufthansa
Wed 12/316:30 amFLR - DSM
2 stops22h 10mLufthansa
Deal found 11/8$1,257
This Expedia deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:30 pmDSM - FLR
2 stops31h 25mMultiple Airlines
Tue 12/305:00 pmFLR - DSM
2 stops34h 45mMultiple Airlines
Deal found 11/10$1,313
This lastminute.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2412:10 pmDSM - FLR
2 stops16h 10mKLM
Wed 12/316:40 amFLR - DSM
2 stops21h 05mKLM
Deal found 11/9$1,421
This Ovago deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/236:46 pmDSM - FLR
2 stops34h 49mLufthansa
Tue 12/3010:20 amFLR - DSM
2 stops42h 20mLufthansa
Deal found 11/8$1,478
This lol.travel deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/248:47 amDSM - FLR
2 stops25h 03mIberia
Wed 12/316:55 amFLR - DSM
2 stops22h 12mIberia
Deal found 11/9$1,485

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 10, 2025.
Use the filters below to find and compare flights from Des Moines to Florence that are best for you.

Fly from

Des Moines

Fly to

Florence

Route

Depart

Return

Price

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Mon 3/9

1:31 pm-12:35 pm

2 stops17h 04m

Florence Peretola

Sun 3/29

8:15 am-9:52 pm

2 stops20h 37m

$848

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Thu 3/12

8:00 am-2:20 pm

2 stops24h 20m

Florence Peretola

Sun 3/29

8:15 am-9:52 pm

2 stops20h 37m

$900

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Tue 1/6

6:48 pm-1:50 pm

2 stops36h 02m

Florence Peretola

Sat 4/25

6:30 am-9:52 pm

2 stops22h 22m

$910

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Tue 12/23

6:46 pm-12:35 pm

2 stops34h 49m

Florence Peretola

Tue 12/30

6:30 am-11:58 pm

2 stops24h 28m

$1,053

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Wed 12/24

3:14 pm-12:35 pm

2 stops14h 21m

Florence Peretola

Wed 12/31

9:35 am-9:40 pm

2 stops19h 05m

$1,202

Des MoinesFlorence

DSM - FLR

DSMFLR

Des Moines

Wed 12/24

3:14 pm-12:35 pm

2 stops14h 21m

Florence Peretola

Wed 12/31

6:30 am-9:40 pm

2 stops22h 10m

$1,257

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/9

Compare providers for flights from Des Moines to Florence

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Florence in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
AranGrantPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Des Moines-Florence flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Des Moines-Florence flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Des Moines-Florence flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Des Moines-Florence flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Florence flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Florence

Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated November 10, 2025.
See what other customers who have flown with Delta, United Airlines, and Lufthansa from Des Moines to Florence have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,003 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Boarding

8.1

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,003 reviews
Delta
7.9
Good
8,003 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Boarding

8.1

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,012 reviews
Delta
7.9
Good
8,003 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Boarding

8.1

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Lufthansa
6.8
Okay
7,564 reviews
Delta
7.9
Good
8,003 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Boarding

8.1

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Florence?

    Airlines like United Airlines fly from Des Moines to Florence in about 17h 04m. The time it takes to get you to your destination can typically vary by up to . Des Moines and Florence are separated by a distance of 4923 mi.

  • What are the cheapest airlines flying from Des Moines to Florence round-trip?

    Flying on Delta is currently your cheapest option to Florence, with prices starting at $660. Additional round-trip tickets that might be worth considering are offered by United Airlines and Lufthansa, with the lowest prices starting at $790 and $811, respectively. Delta is priced at 46% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Des Moines to Florence that include hotel bookings?

    Yes. In addition to deals on Des Moines to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Florence.

  • Can I find deals for business class flights from Des Moines to Florence?

    Yes. Cheapflights offers flight deals from Des Moines to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top 3 airlines flying from Des Moines to Florence

Discover the top 3 airlines that operate flights from Des Moines to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 10, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$660Average$1,541FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$790Average$1,242FlexibilityNo cancel feeOn-time69%
LufthansaCheapest$811Average$1,367FlexibilityNo cancel feeOn-time76%

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