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$224+ Cheap flights from Reno to Florence, SC (RNO - FLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/28. Fares are subject to change and may not be available on all flights or dates of travel.
RNO — FLO
Mar 23 — Mar 301
Mon 3/23
Mon 3/30
1 adult, Economy
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Cheap flight deals from Reno to Florence

One-way flights from Reno to Florence
Search for one-way flight options from Reno to Florence. Find affordable one-way fares based on user searches. Data last updated February 21, 2026.

This American Airlines deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:00 am
RNO
-
FLO
2 stops13h 42m
American Airlines
Deal found 2/17$224
This American Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:00 am
RNO
-
FLO
2 stops14h 52m
American Airlines
Deal found 2/20$384

Find flight deals from Reno to Florence

Discover tips and strategies to find the most affordable flight options for your journey from Reno (RNO) to Florence (FLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 21, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars
Provider with most accurate pricing for Reno-Florence flight deals.
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Provider most trusted by Cheapflights users for Reno-Florence flights.
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Reno to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 21, 2026.
Use the filters below to find and compare flights from Reno to Florence that are best for you.

Fly from

Reno

Fly to

Florence

Route

Depart

Return

Price

RenoFlorence

RNO - FLO

RNOFLO

Reno

Wed 4/29

6:00 am-11:52 pm

2 stops14h 52m

$224

RenoFlorence

RNO - FLO

RNOFLO

Reno

Tue 4/28

6:00 am-10:42 pm

2 stops13h 42m

$224

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/17

  • Most accurate provider: When it comes to deals on Reno-Florence, South Carolina flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Reno-Florence, South Carolina flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Reno-Florence, South Carolina flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Reno-Florence, South Carolina flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Reno-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Reno to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Reno with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Reno to Florence

What is the cheapest month to book a flight from Reno to Florence, South Carolina?

Currently, October is the cheapest month in which you can book a flight from Reno to Florence, South Carolina (average of $246). Flying from Reno to Florence, South Carolina in February is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Reno to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find deals for flights from Reno to Florence that include hotel bookings?

    Yes. In addition to deals on Reno to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Reno to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Reno to Florence.

  • Can I find deals for business class flights from Reno to Florence?

    Yes. Cheapflights offers flight deals from Reno to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Reno to Florence, South Carolina?

    Currently, October is the cheapest month in which you can book a flight from Reno to Florence, South Carolina (average of $246). Flying from Reno to Florence, South Carolina in February is currently the most expensive (average of $369). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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