HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Florence

$418+ Cheap flights from Columbus (CMH) to Florence, SC (FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/27. Fares are subject to change and may not be available on all flights or dates of travel.
CMH — FLO
Jan 2 — Jan 91
Fri 1/2
Fri 1/9
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Columbus to Florence with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Columbus to Florence

Cheapest flights from Columbus to Florence
Explore the most affordable flight options available from Columbus to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 3, 2025.

This American Airlines deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/612:33 pmCMH - FLO
1 stop5h 32mAmerican Airlines
Sat 12/135:15 amFLO - CMH
1 stop6h 27mAmerican Airlines
Deal found 12/1$481
This American Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/298:23 amCMH - FLO
1 stop4h 03mAmerican Airlines
Sun 1/46:30 pmFLO - CMH
1 stop6h 02mAmerican Airlines
Deal found 12/2$517
This American Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/286:36 amCMH - FLO
1 stop6h 06mAmerican Airlines
Sat 1/35:15 amFLO - CMH
2 stops6h 54mAmerican Airlines
Deal found 12/2$522

Find flight deals from Columbus to Florence

Discover tips and strategies to find the most affordable flight options for your journey from Columbus (CMH) to Florence (FLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 3, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$418
(American Airlines)
Provider with most accurate pricing for Columbus-Florence flight deals.
Search Deals
Provider most trusted by Cheapflights users for Columbus-Florence flights.
Search Deals
From Columbus to Florence
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbus to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 3, 2025.
Use the filters below to find and compare flights from Columbus Airport to Florence that are best for you.

Fly from

Columbus

Fly to

Florence

Route

Depart

Return

Price

ColumbusFlorence

CMH - FLO

CMHFLO

Columbus

Tue 1/27

6:00 am-5:09 pm

2 stops11h 09m

Florence

Sat 1/31

6:15 am-9:30 pm

2 stops15h 15m

$418

ColumbusFlorence

CMH - FLO

CMHFLO

Columbus

Tue 12/16

6:00 am-10:50 am

1 stop4h 50m

Florence

Sat 12/20

6:30 pm-10:28 pm

1 stop3h 58m

$481

ColumbusFlorence

CMH - FLO

CMHFLO

Columbus

Mon 12/29

8:23 am-12:26 pm

1 stop4h 03m

Florence

Sun 1/4

6:30 pm-12:32 am

1 stop6h 02m

$517

ColumbusFlorence

CMH - FLO

CMHFLO

Columbus

Sun 12/28

6:36 am-12:42 pm

1 stop6h 06m

Florence

Sat 1/3

5:15 am-12:09 pm

2 stops6h 54m

$522

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/1

Compare providers for flights from Columbus to Florence

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Columbus to Florence in December.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
ExpediaPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Columbus Airport-Florence, South Carolina flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Columbus Airport-Florence, South Carolina flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Columbus Airport-Florence, South Carolina flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Columbus Airport-Florence, South Carolina flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Columbus Airport-Florence, South Carolina flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Columbus to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Columbus with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbus Airport to Florence

What is the cheapest month to book a flight from Columbus Airport to Florence, South Carolina?

Currently, January is the cheapest month in which you can book a flight from Columbus Airport to Florence, South Carolina (average of $83). Flying from Columbus Airport to Florence, South Carolina in April is currently the most expensive (average of $133). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Columbus to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from Columbus?

    Florence (FLO), located 2.3 mi from the city center, is the airport you fly into when you book flights from Columbus to Florence. 0 airlines have flights to Florence from Columbus on a regular basis. Booking flights from Columbus to Florence should not be difficult; the airport handles an average of 0 inbound flights from Columbus per day.

  • How long is the flight from Columbus Airport to Florence, South Carolina?

    Airlines like American Airlines fly from Columbus Airport to Florence, South Carolina in about 11h 09m. The time it takes to get you to your destination can typically vary by up to . Airlines will cover a distance of 438 mi.

  • Can I find deals for flights from Columbus to Florence that include hotel bookings?

    Yes. In addition to deals on Columbus to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbus to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbus to Florence.

  • Can I find deals for business class flights from Columbus to Florence?

    Yes. Cheapflights offers flight deals from Columbus to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Columbus Airport to Florence, South Carolina?

    Currently, January is the cheapest month in which you can book a flight from Columbus Airport to Florence, South Carolina (average of $83). Flying from Columbus Airport to Florence, South Carolina in April is currently the most expensive (average of $133). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.