$353+ Cheap flights from Phoenix to Florence, SC (FLO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/17. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — FLO
Sep 22 — Sep 291
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Phoenix to Florence with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Phoenix to Florence
Cheapest
Best
Last-minute
One-way
Cheapest flights from Phoenix to FlorenceExplore the most affordable flight options available from Phoenix to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 23, 2026.
Explore the most affordable flight options available from Phoenix to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 23, 2026.
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:00 am -
1 stop6h 09m
Sat 10/102:34 pm -
1 stop8h 04m
Deal found 8/19![American Airlines logo]()
$473
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/198:30 am -
2 stops11h 28m
Sat 9/261:43 pm -
1 stop6h 18m
Deal found 8/22![American Airlines logo]()
$484
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2212:21 pm -
1 stop7h 38m
Wed 8/266:22 am -
1 stop6h 17m
Deal found 8/21![American Airlines logo]()
$535
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2910:32 am -
2 stops9h 27m
Sat 9/59:00 am -
1 stop8h 28m
Deal found 8/20![American Airlines logo]()
$549
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/171:55 pm -
1 stop6h 03m
Sat 9/266:24 am -
1 stop7h 39m
Deal found 8/22![American Airlines logo]()
$562
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/95:00 am -
1 stop6h 09m
Mon 10/122:34 pm -
1 stop8h 04m
Deal found 8/18![American Airlines logo]()
$569
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2312:20 pm -
1 stop7h 38m
Sat 9/266:24 am -
2 stops11h 31m
Deal found 8/20![American Airlines logo]()
$579
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/41:48 pm -
1 stop6h 11m
Tue 9/86:22 am -
1 stop6h 17m
Deal found 8/21![American Airlines logo]()
$593
Best flights from Phoenix to FlorenceDiscover carefully curated flight deals from Phoenix to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 23, 2026.
Discover carefully curated flight deals from Phoenix to Florence that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 23, 2026.
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2312:20 pm -
1 stop7h 38m
Sat 9/261:43 pm -
1 stop6h 18m
Deal found 8/20![American Airlines logo]()
$473
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:00 am -
1 stop6h 09m
Sat 10/102:34 pm -
1 stop8h 04m
Deal found 8/19![American Airlines logo]()
$473
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/291:48 pm -
1 stop6h 11m
Sat 9/52:37 pm -
1 stop6h 14m
Deal found 8/20![American Airlines logo]()
$535
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/92:05 pm -
1 stop6h 52m
Mon 10/122:34 pm -
1 stop6h 51m
Deal found 8/21![American Airlines logo]()
$569
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/41:48 pm -
1 stop6h 11m
Tue 9/86:22 am -
1 stop6h 17m
Deal found 8/21![American Airlines logo]()
$593
Last-minute flights from Phoenix to FlorenceDiscover last-minute flight deals from Phoenix to Florence. Data last updated August 23, 2026 and is based on user searches.
Discover last-minute flight deals from Phoenix to Florence. Data last updated August 23, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2212:21 pm -
1 stop7h 38m
Wed 8/266:22 am -
1 stop6h 17m
Deal found 8/21![American Airlines logo]()
$535
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2910:32 am -
2 stops9h 27m
Sat 9/59:00 am -
1 stop8h 28m
Deal found 8/20![American Airlines logo]()
$549
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/41:48 pm -
1 stop6h 11m
Tue 9/86:22 am -
1 stop6h 17m
Deal found 8/21![American Airlines logo]()
$593
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/171:55 pm -
1 stop6h 03m
Sat 9/266:24 am -
1 stop7h 39m
Deal found 8/22![American Airlines logo]()
$562
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/198:30 am -
2 stops11h 28m
Sat 9/261:43 pm -
1 stop6h 18m
Deal found 8/22![American Airlines logo]()
$484
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2312:20 pm -
1 stop7h 38m
Sat 9/261:43 pm -
1 stop6h 18m
Deal found 8/20![American Airlines logo]()
$473
One-way flights from Phoenix to FlorenceSearch for one-way flight options from Phoenix to Florence. Find affordable one-way fares based on user searches. Data last updated August 23, 2026.
Search for one-way flight options from Phoenix to Florence. Find affordable one-way fares based on user searches. Data last updated August 23, 2026.
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/171:55 pm -
1 stop6h 03m
Deal found 8/19![American Airlines logo]()
$353
Find flight deals from Phoenix to Florence
Discover tips and strategies to find the most affordable flight options for your journey from Phoenix (PH1) to Florence (FLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 23, 2026.
Round-trip from | $473 (American Airlines) |
|---|---|
One-way from | $353 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Phoenix to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 23, 2026.
Use the filters below to find and compare flights from Phoenix to Florence that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PhoenixFlorence
PHX Phoenix Sky Harbor Intl - FLO Florence
PHXFLO
Phoenix Sky Harbor Intl
Wed 9/23
12:20 pm-10:58 pm
1 stop7h 38m
Florence
Sat 9/26
1:43 pm-5:01 pm
1 stop6h 18m
$473
PhoenixFlorence
PHX Phoenix Sky Harbor Intl - FLO Florence
PHXFLO
Phoenix Sky Harbor Intl
Wed 10/7
5:00 am-2:09 pm
1 stop6h 09m
Florence
Sat 10/10
2:34 pm-7:38 pm
1 stop8h 04m
$473
Quickest round-trip
PhoenixFlorence
PHX Phoenix Sky Harbor Intl - FLO Florence
PHXFLO
Phoenix Sky Harbor Intl
Sat 8/29
1:48 pm-10:59 pm
1 stop6h 11m
Florence
Sat 9/5
2:37 pm-5:51 pm
1 stop6h 14m
$535
PhoenixFlorence
PHX Phoenix Sky Harbor Intl - FLO Florence
PHXFLO
Phoenix Sky Harbor Intl
Fri 10/9
2:05 pm-11:57 pm
1 stop6h 52m
Florence
Mon 10/12
2:34 pm-6:25 pm
1 stop6h 51m
$569
PhoenixFlorence
PHX Phoenix Sky Harbor Intl - FLO Florence
PHXFLO
Phoenix Sky Harbor Intl
Fri 9/4
1:48 pm-10:59 pm
1 stop6h 11m
Florence
Tue 9/8
6:22 am-9:39 am
1 stop6h 17m
$593
Cheapest one-way
Quickest one-way
PhoenixFlorence
PHX Phoenix Sky Harbor Intl - FLO Florence
PHXFLO
Phoenix Sky Harbor Intl
Thu 9/17
1:55 pm-10:58 pm
1 stop6h 03m
$353
Sorted by cheapest first
Best time to book a flight from Phoenix to Florence
Have a flexible travel schedule? Discover the best time to fly to Florence from Phoenix with our price prediction graph.
PH1-FLO
PHX-FLO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Phoenix to Florence
PH1-FLO
PHX-FLO
No data available for this route at this time. Please check back soon.
Related info for your journey
Find useful and relevant information for your journey from Phoenix to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Florence?
Book flights to Florence if you plan to visit one of these locationsSumter
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Florence flight routes
Other flight options
Popular flights