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$423+ Cheap flights from Phoenix to Florence, SC (FLO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/20. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — FLO
Mar 31 — Apr 71
Tue 3/31
Tue 4/7
1 adult, Economy
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Cheap flight deals from Phoenix to Florence

Cheapest flights from Phoenix to Florence
Explore the most affordable flight options available from Phoenix to Florence. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 1, 2026.

This American Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:30 am
PHX
-
FLO
1 stop6h 20m
American Airlines
Tue 5/262:35 pm
FLO
-
PHX
1 stop6h 43m
American Airlines
Deal found 2/26$423
This American Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/155:00 am
PHX
-
FLO
1 stop7h 50m
American Airlines
Mon 4/204:16 pm
FLO
-
PHX
2 stops10h 17m
American Airlines
Deal found 2/26$466
This American Airlines deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/17:30 am
PHX
-
FLO
1 stop8h 20m
American Airlines
Sat 3/76:25 pm
FLO
-
PHX
1 stop8h 42m
American Airlines
Deal found 2/26$533
This American Airlines deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/136:30 am
PHX
-
FLO
1 stop8h 20m
American Airlines
Sun 3/156:20 pm
FLO
-
PHX
1 stop6h 51m
American Airlines
Deal found 3/1$581
This American Airlines deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/292:50 pm
PHX
-
FLO
1 stop6h 07m
American Airlines
Sun 4/55:16 am
FLO
-
PHX
1 stop9h 05m
American Airlines
Deal found 3/1$607

Find flight deals from Phoenix to Florence

Discover tips and strategies to find the most affordable flight options for your journey from Phoenix (PH1) to Florence (FLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 1, 2026.

Round-trip from

$423
(American Airlines)
From Phoenix to Florence
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Phoenix to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 1, 2026.
Use the filters below to find and compare flights from Phoenix to Florence that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PhoenixFlorence

PHX - FLO

PHXFLO

Phoenix Sky Harbor Intl

Wed 4/15

11:50 am-11:52 pm

2 stops9h 02m

Florence

Mon 4/20

4:16 pm-11:33 pm

2 stops10h 17m

$472

PhoenixFlorence

PHX - FLO

PHXFLO

Phoenix Sky Harbor Intl

Wed 5/20

6:30 am-3:50 pm

1 stop6h 20m

Florence

Tue 5/26

2:35 pm-9:08 pm

2 stops9h 33m

$546

PhoenixFlorence

PHX - FLO

PHXFLO

Phoenix Sky Harbor Intl

Fri 3/13

6:30 am-5:50 pm

1 stop8h 20m

Florence

Sun 3/15

6:20 pm-10:11 pm

1 stop6h 51m

$581

PhoenixFlorence

PHX - FLO

PHXFLO

Phoenix Sky Harbor Intl

Sun 3/29

2:50 pm-11:57 pm

1 stop6h 07m

Florence

Sun 4/5

5:16 am-11:21 am

1 stop9h 05m

$607

PhoenixFlorence

PHX - FLO

PHXFLO

Phoenix Sky Harbor Intl

Sun 7/26

5:00 am-2:11 pm

1 stop6h 11m

Florence

Sun 8/2

2:36 pm-10:11 pm

2 stops10h 35m

$771

PhoenixFlorence

PHX - FLO

PHXFLO

Phoenix Sky Harbor Intl

Sun 3/15

6:30 am-5:50 pm

1 stop8h 20m

Florence

Thu 3/19

5:16 am-9:16 am

1 stop7h 00m

$871

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/26

Sorted by cheapest first

Best time to book a flight from Phoenix to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Phoenix with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Phoenix to Florence

What is the cheapest month to book a flight from Phoenix to Florence, South Carolina?

Currently, February is the cheapest month in which you can book a flight from Phoenix to Florence, South Carolina (average of $169). Flying from Phoenix to Florence, South Carolina in December is currently the most expensive (average of $268). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Phoenix to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from Phoenix?

    For a flight from Phoenix to Florence, you will be flying into Florence. Florence (FLO) is just 2.3 mi from the center of the city. Florence is the only Florence airport and it handles 0 inbound flights from Phoenix per day. 0 airlines have flights to Florence from Phoenix on a regular basis.

  • How long is the flight from Phoenix to Florence, South Carolina?

    Departing from Phoenix to Florence, South Carolina will take you 9h 02m. Airlines will cover a distance of 1844 mi.

  • Can I find deals for flights from Phoenix to Florence that include hotel bookings?

    Yes. In addition to deals on Phoenix to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Phoenix to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Phoenix to Florence.

  • Can I find deals for business class flights from Phoenix to Florence?

    Yes. Cheapflights offers flight deals from Phoenix to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Phoenix to Florence, South Carolina?

    Currently, February is the cheapest month in which you can book a flight from Phoenix to Florence, South Carolina (average of $169). Flying from Phoenix to Florence, South Carolina in December is currently the most expensive (average of $268). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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