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$377+ Cheap flights from Phoenix to Florence, SC (FLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/20. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — FLO
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Find flight deals from Phoenix to Florence

One-way flights from Phoenix to Florence
Search for one-way flight options from Phoenix to Florence. Find affordable one-way fares based on user searches. Data last updated July 31, 2025.

This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2012:24 amPHX - FLO
2 stops20h 35mAmerican Airlines
Deal found 7/30$377

Cheapflights Fare Finder

 
Customize your flight search to find flights from Phoenix to Florence that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Phoenix to Florence that are best for you.

Fly from

Phoenix

Fly to

Florence

Route

Depart

Return

Price

PhoenixFlorence

PHX - FLO

PHXFLO

Phoenix Sky Harbor Intl

Wed 8/20

12:24 am-11:59 pm

2 stops20h 35m

$377

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Best time to book a flight from Phoenix to Florence

Have a flexible travel schedule? Discover the best time to fly to Florence from Phoenix with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Phoenix to Florence

What is the cheapest month to book a flight from Phoenix to Florence, South Carolina?

Currently, January is the cheapest month in which you can book a flight from Phoenix to Florence, South Carolina (average of $366). Flying from Phoenix to Florence, South Carolina in October is currently the most expensive (average of $481). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PHX to FLO?

Find hourly flight availability from Phoenix to Florence. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Phoenix to Florence, South Carolina as you normally would.

Reviews of airlines servicing Florence

Get insights into the airlines that provide service to Florence. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florence. Reviews last updated July 31, 2025.
Read through reviews of airlines operating flights from Phoenix to Florence, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Overall

7.2

Boarding

7.5

Food

6.5

Crew

8.0

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Andrew,May 2025

LAX - MIA

2 hour delay. Discovered an engine problem late, we boarded the plane and they asked us to come off. To add insult to injury nothing was given to passengers to make amends. No free drink. No extra food or snacks. No free WiFi. Gimme a break
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Comfort

7.2

Overall

7.2

Boarding

7.5

Food

6.5

Crew

8.0

Entertainment

6.9

Reviews

1 / 20
2.0
Mediocre

Andrew,May 2025

LAX - MIA

2 hour delay. Discovered an engine problem late, we boarded the plane and they asked us to come off. To add insult to injury nothing was given to passengers to make amends. No free drink. No extra food or snacks. No free WiFi. Gimme a break

Related info for your journey

Find useful and relevant information for your journey from Phoenix to Florence. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Florence from Phoenix?

    For a flight from Phoenix to Florence, you will be flying into Florence. Florence (FLO) is just 2.3 mi from the center of the city. Florence is the only Florence airport and it handles 0 inbound flights from Phoenix per day. 1 airline has flights to Florence from Phoenix on a regular basis.

  • Can I find deals for flights from Phoenix to Florence that include hotel bookings?

    Yes. In addition to deals on Phoenix to Florence flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Phoenix to Florence?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Phoenix to Florence.

  • Can I find deals for business class flights from Phoenix to Florence?

    Yes. Cheapflights offers flight deals from Phoenix to Florence by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Phoenix to Florence, South Carolina?

    Currently, January is the cheapest month in which you can book a flight from Phoenix to Florence, South Carolina (average of $366). Flying from Phoenix to Florence, South Carolina in October is currently the most expensive (average of $481). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
Sumter
Hartsville
Darlington

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Top airline flying from Phoenix to Florence

Discover the top airline that operate flights from Phoenix to Florence. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$436Average$616FlexibilityNo cancel feeOn-time71%

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