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Durham

$43+ Cheap flights from South Carolina to Durham, NC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/15. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — RDU
Feb 15 — Feb 221
Sun 2/15
Sun 2/22
1 adult, Economy
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Cheap flight deals from South Carolina to Durham

Keep the following information in mind while searching for South Carolina to Durham flight deals. Data was last updated January 16, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$100
(Kiwi.com)

One-way from

$43
(Kiwi.com)
Provider with most accurate pricing for Myrtle Beach Intl-Raleigh-Durham flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Raleigh-Durham flights.
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From South Carolina to Durham
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One-way flight from South Carolina to Durham
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Find flight deals from South Carolina to Durham

Cheapest flights from South Carolina to Durham
Explore the most affordable flight options available from South Carolina to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 16, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/126:15 am
CHS
-
RDU
1 stop3h 52m
Breeze Airways
Sun 2/1510:47 am
RDU
-
CHS
1 stop3h 49m
Breeze Airways
Deal found 1/14$100
This Kiwi.com deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/156:15 am
CHS
-
RDU
1 stop3h 52m
Multiple Airlines
Mon 2/166:08 pm
RDU
-
CHS
1 stop21h 47m
Multiple Airlines
Deal found 1/14$138
This Kiwi.com deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/121:17 pm
CLT
-
RDU
1 stop7h 57m
Frontier
Thu 2/1910:47 am
RDU
-
CLT
1 stop22h 45m
Frontier
Deal found 1/15$142
This Kiwi.com deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/195:00 pm
CHS
-
RDU
1 stop24h 11m
Multiple Airlines
Sun 2/2210:47 am
RDU
-
CHS
1 stop3h 49m
Multiple Airlines
Deal found 1/15$143
This Kiwi.com deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/116:01 pm
CLT
-
RDU
1 stop13h 51m
Multiple Airlines
Wed 2/186:14 pm
RDU
-
CLT
1 stop25h 03m
Multiple Airlines
Deal found 1/13$151
This Kiwi.com deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/189:21 am
CLT
-
RDU
1 stop7h 50m
Multiple Airlines
Wed 2/256:14 pm
RDU
-
CLT
1 stop25h 03m
Multiple Airlines
Deal found 1/15$152
This Kiwi.com deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/226:15 am
CHS
-
RDU
1 stop3h 52m
Breeze Airways
Sun 1/2510:47 am
RDU
-
CHS
1 stop3h 49m
Breeze Airways
Deal found 1/14$167
This Kiwi.com deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/126:15 am
CHS
-
RDU
1 stop3h 52m
Multiple Airlines
Sun 2/156:10 am
RDU
-
CHS
2 stops11h 30m
Multiple Airlines
Deal found 1/14$181
This Kiwi.com deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/149:21 am
CLT
-
RDU
1 stop7h 50m
Spirit Airlines
Sat 2/216:08 pm
RDU
-
CLT
1 stop5h 51m
Spirit Airlines
Deal found 1/15$182
This Kiwi.com deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/298:00 am
SAV
-
RDU
1 stop6h 13m
Multiple Airlines
Sun 2/17:19 pm
RDU
-
SAV
1 stop17h 03m
Multiple Airlines
Deal found 1/15$183
This Kiwi.com deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/309:29 pm
CHS
-
RDU
1 stop11h 34m
Breeze Airways
Mon 2/29:15 pm
RDU
-
CHS
1 stop11h 23m
Breeze Airways
Deal found 1/13$185
This Kiwi.com deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/291:17 pm
SAV
-
RDU
1 stop28h 44m
Multiple Airlines
Mon 2/23:08 pm
RDU
-
SAV
1 stop8h 17m
Multiple Airlines
Deal found 1/14$188

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 16, 2026.
Use the filters below to find and compare flights from South Carolina to Durham that are best for you.

Fly from

South Carolina

Fly to

Durham

Route

Depart

Return

Price

CharlestonRaleigh

CHS - RDU

CHSRDU

Charleston

Thu 2/12

6:15 am-10:07 am

Nonstop3h 52m

Raleigh-Durham

Sun 2/15

10:47 am-2:36 pm

Nonstop3h 49m

$112

CharlestonRaleigh

CHS - RDU

CHSRDU

Charleston

Sun 2/15

6:15 am-10:07 am

1 stop3h 52m

Raleigh-Durham

Mon 2/16

6:08 pm-3:55 pm

1 stop21h 47m

$138

CharlotteRaleigh

CLT - RDU

CLTRDU

Charlotte Douglas

Thu 2/12

1:17 pm-9:14 pm

1 stop7h 57m

Raleigh-Durham

Thu 2/19

10:47 am-9:32 am

1 stop22h 45m

$142

CharlestonRaleigh

CHS - RDU

CHSRDU

Charleston

Thu 2/19

5:00 pm-5:11 pm

1 stop24h 11m

Raleigh-Durham

Sun 2/22

10:47 am-2:36 pm

1 stop3h 49m

$143

CharlotteRaleigh

CLT - RDU

CLTRDU

Charlotte Douglas

Wed 2/11

6:01 pm-7:52 am

1 stop13h 51m

Raleigh-Durham

Wed 2/18

6:14 pm-7:17 pm

1 stop25h 03m

$151

CharlotteRaleigh

CLT - RDU

CLTRDU

Charlotte Douglas

Wed 2/18

9:21 am-5:11 pm

1 stop7h 50m

Raleigh-Durham

Wed 2/25

6:14 pm-7:17 pm

1 stop25h 03m

$152

CharlotteRaleigh

CLT - RDU

CLTRDU

Charlotte Douglas

Sat 2/14

9:21 am-5:11 pm

1 stop7h 50m

Raleigh-Durham

Sat 2/21

6:08 pm-11:59 pm

1 stop5h 51m

$182

SavannahRaleigh

SAV - RDU

SAVRDU

Savannah/Hilton Head

Thu 1/29

8:00 am-2:13 pm

1 stop6h 13m

Raleigh-Durham

Sun 2/1

7:19 pm-12:22 pm

1 stop17h 03m

$183

CharlestonRaleigh

CHS - RDU

CHSRDU

Charleston

Fri 1/30

9:29 pm-9:03 am

1 stop11h 34m

Raleigh-Durham

Mon 2/2

9:15 pm-8:38 am

1 stop11h 23m

$185

SavannahRaleigh

SAV - RDU

SAVRDU

Savannah/Hilton Head

Thu 1/29

1:17 pm-6:01 pm

1 stop28h 44m

Raleigh-Durham

Mon 2/2

3:08 pm-11:25 pm

1 stop8h 17m

$188

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/14

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Durham

Have a flexible travel schedule? Discover the best time to fly to Durham from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Durham

What is the cheapest month to book a flight from South Carolina to Durham?

Currently, February is the cheapest month in which you can book a flight from South Carolina to Durham (average of $96). Flying from South Carolina to Durham in December is currently the most expensive (average of $398). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to DU8?

Find hourly flight availability from South Carolina to Durham. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 16, 2026.

Unlike in the morning, when flights are generally more expensive, you can save up to 52% on flights from South Carolina to Durham by exploring options for tickets in the evening.

What is the cheapest day to fly from South Carolina to Durham?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Durham. Price data was last updated on January 10, 2026.

Travelers seeking maximum savings on their South Carolina to Durham flight should consider departing on Thursday afternoons when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Durham?

    A quick flight from South Carolina to Durham can take about 3h 52m. Breeze Airways provides one of the quickest options available for as low as $112. South Carolina and Durham are separated by a distance of 218 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from South Carolina to Durham one-way?

    The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $136. However, be on the lookout for offers from Frontier and JetBlue, as they are both options that can get you from South Carolina to Durham for a low price.

  • What are the most popular routes from South Carolina to Durham?

    When deciding which route to take from South Carolina to Durham consider Charleston - Raleigh-Durham, Charlotte Douglas - Raleigh-Durham or Savannah/Hilton Head - Raleigh-Durham as they are the most popular.

  • Can I find deals for flights from South Carolina to Durham that include hotel bookings?

    Yes. In addition to deals on South Carolina to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Durham?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Durham.

  • Can I find deals for business class flights from South Carolina to Durham?

    Yes. Cheapflights offers flight deals from South Carolina to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Durham?

    Currently, February is the cheapest month in which you can book a flight from South Carolina to Durham (average of $96). Flying from South Carolina to Durham in December is currently the most expensive (average of $398). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Durham

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from South Carolina to Durham

Discover the top 2 airlines that operate flights from South Carolina to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 16, 2026.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$95Average$229FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$221Average$440FlexibilityNo cancel feeOn-time71%

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