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Durham

$90+ Cheap flights from South Carolina to Durham, NC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/11. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — RDU
Jun 27 — Jul 41
Sat 6/27
Sat 7/4
1 adult, Economy
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Cheap flight deals from South Carolina to Durham

Cheapest flights from South Carolina to Durham
Explore the most affordable flight options available from South Carolina to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 28, 2026.

This Kiwi.com deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/238:25 am
GSP
-
RDU
1 stop9h 50m
Multiple Airlines
Sat 8/19:48 pm
RDU
-
GSP
1 stop9h 47m
Multiple Airlines
Deal found 5/27$188
This Kiwi.com deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/223:23 pm
CHS
-
RDU
1 stop18h 37m
Breeze Airways
Mon 6/292:32 pm
RDU
-
CHS
1 stop18h 06m
Breeze Airways
Deal found 5/25$221
This Kiwi.com deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:56 pm
CHS
-
RDU
1 stop12h 03m
Breeze Airways
Mon 8/178:29 pm
RDU
-
CHS
1 stop12h 09m
Breeze Airways
Deal found 5/25$233
This JetBlue deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2011:00 am
CHS
-
RDU
1 stop5h 46m
JetBlue
Mon 8/2410:59 am
RDU
-
CHS
1 stop8h 20m
JetBlue
Deal found 5/24$241
This Priceline deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/310:49 am
SAV
-
RDU
1 stop5h 59m
JetBlue
Mon 7/611:03 am
RDU
-
SAV
1 stop7h 29m
JetBlue
Deal found 5/26$253
This Kiwi.com deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/112:53 pm
CHS
-
RDU
1 stop18h 26m
Multiple Airlines
Mon 6/155:07 pm
RDU
-
CHS
1 stop15h 31m
Multiple Airlines
Deal found 5/27$254
This Kiwi.com deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/216:45 am
CHS
-
RDU
1 stop3h 51m
Breeze Airways
Mon 6/228:29 pm
RDU
-
CHS
1 stop12h 09m
Breeze Airways
Deal found 5/23$255
This Kiwi.com deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/228:28 pm
GSP
-
RDU
1 stop13h 32m
Breeze Airways
Mon 6/299:03 pm
RDU
-
GSP
1 stop18h 03m
Breeze Airways
Deal found 5/23$259
This Kiwi.com deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/159:28 pm
CHS
-
RDU
1 stop12h 15m
Multiple Airlines
Mon 6/228:29 pm
RDU
-
CHS
1 stop12h 09m
Multiple Airlines
Deal found 5/26$260
This American Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/232:02 pm
CHS
-
RDU
1 stop7h 14m
American Airlines
Tue 6/3010:35 am
RDU
-
CHS
1 stop8h 32m
American Airlines
Deal found 5/24$263
This Kiwi.com deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/123:23 pm
CHS
-
RDU
1 stop17h 37m
Breeze Airways
Tue 6/164:15 pm
RDU
-
CHS
1 stop17h 23m
Breeze Airways
Deal found 5/24$265
This Kiwi.com deal was found by Cheapflights users on 5/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/163:19 pm
GSP
-
RDU
2 stops19h 00m
Multiple Airlines
Sun 7/198:56 am
RDU
-
GSP
1 stop11h 16m
Multiple Airlines
Deal found 5/27$294

Find flight deals from South Carolina to Durham

Keep the following information in mind while searching for South Carolina to Durham flight deals. Data was last updated May 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$188
(Kiwi.com)

One-way from

$90
(Mytrip)
Provider with most accurate pricing for Myrtle Beach Intl-Raleigh-Durham flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Raleigh-Durham flights.
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From South Carolina to Durham
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One-way flight from South Carolina to Durham
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Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 28, 2026.
Use the filters below to find and compare flights from South Carolina to Durham that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CharlestonRaleigh

CHS - RDU

CHSRDU

Charleston

Wed 8/12

8:56 pm-8:59 am

1 stop12h 03m

Raleigh-Durham

Mon 8/17

8:29 pm-8:38 am

1 stop12h 09m

$233

CharlestonRaleigh

CHS - RDU

CHSRDU

Charleston

Thu 8/20

11:00 am-4:46 pm

1 stop5h 46m

Raleigh-Durham

Mon 8/24

10:59 am-7:19 pm

1 stop8h 20m

$241

SavannahRaleigh

SAV - RDU

SAVRDU

Savannah/Hilton Head

Thu 8/27

10:55 am-4:46 pm

1 stop5h 51m

Raleigh-Durham

Mon 8/31

10:59 am-6:20 pm

1 stop7h 21m

$253

CharlestonRaleigh

CHS - RDU

CHSRDU

Charleston

Thu 6/11

2:53 pm-9:19 am

1 stop18h 26m

Raleigh-Durham

Mon 6/15

5:07 pm-8:38 am

1 stop15h 31m

$254

GreenvilleRaleigh

GSP - RDU

GSPRDU

Greenville

Thu 7/16

3:19 pm-10:19 am

2 stops19h 00m

Raleigh-Durham

Sun 7/19

8:56 am-8:12 pm

1 stop11h 16m

$294

GreenvilleRaleigh

GSP - RDU

GSPRDU

Greenville

Thu 7/23

3:46 pm-8:48 am

2 stops17h 02m

Raleigh-Durham

Sat 8/1

9:48 pm-7:35 am

1 stop9h 47m

$296

GreenvilleRaleigh

GSP - RDU

GSPRDU

Greenville

Fri 6/19

10:26 am-8:58 am

1 stop22h 32m

Raleigh-Durham

Mon 6/22

9:03 pm-3:06 pm

1 stop18h 03m

$309

CharlestonRaleigh

CHS - RDU

CHSRDU

Charleston

Tue 6/23

8:00 am-7:05 pm

2 stops11h 05m

Raleigh-Durham

Tue 6/30

10:22 pm-9:08 am

1 stop10h 46m

$312

SavannahRaleigh

SAV - RDU

SAVRDU

Savannah/Hilton Head

Wed 6/24

1:25 pm-10:15 pm

2 stops8h 50m

Raleigh-Durham

Wed 7/1

10:25 am-7:40 pm

2 stops9h 15m

$313
Quickest round-trip

CharlestonRaleigh

CHS - RDU

CHSRDU

Charleston

Sun 6/7

6:45 am-10:36 am

1 stop3h 51m

Raleigh-Durham

Thu 6/11

11:16 am-3:06 pm

1 stop3h 50m

$327

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/26

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from South Carolina to Durham

Have a flexible travel schedule? Discover the best time to fly to Durham from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Durham
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Durham?

    A quick flight from South Carolina to Durham can take about 5h 46m. Breeze Airways provides one of the quickest options available for as low as $241. South Carolina and Durham are separated by a distance of 218 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from South Carolina to Durham one-way?

    The cheapest airline one-way is Breeze Airways, with whom users have recently found tickets for as low as $82. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from South Carolina to Durham for a low price.

  • What are the most popular routes from South Carolina to Durham?

    When deciding which route to take from South Carolina to Durham consider Charlotte Douglas - Raleigh-Durham, Greenville - Raleigh-Durham or Savannah/Hilton Head - Raleigh-Durham as they are the most popular.

  • Can I find deals for flights from South Carolina to Durham that include hotel bookings?

    Yes. In addition to deals on South Carolina to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Durham?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Durham.

  • Can I find deals for business class flights from South Carolina to Durham?

    Yes. Cheapflights offers flight deals from South Carolina to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for South Carolina to Durham

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from South Carolina to Durham

Discover the top airline that operate flights from South Carolina to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$221Average$489FlexibilityNo cancel feeOn-time71%

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