What are the cheapest airlines to fly from South Carolina to Durham one-way?

The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $137. However, be on the lookout for offers from JetBlue and American Airlines, as they are both options that can get you from South Carolina to Durham for a low price.

In terms of precipitation, rainfall in Durham ranges from 2.9 - 4.7 inches per month. July is typically the wettest month, when rainfall can reach 4.7 in. April is typically the driest time to visit Durham when rainfall is around 2.9 in.

If weather is an important factor for your trip to Durham, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

What are the most popular routes from South Carolina to Durham?

When deciding which route to take from South Carolina to Durham consider Charlotte Douglas - Raleigh-Durham, Greenville - Raleigh-Durham or Savannah/Hilton Head - Raleigh-Durham as they are the most popular.

What is the cheapest time of day to fly from SC to DU8?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Durham as you normally would.

Can I find deals for flights from South Carolina to Durham that include hotel bookings?

Yes. In addition to deals on South Carolina to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from South Carolina to Durham?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Durham.

Can I find deals for business class flights from South Carolina to Durham?

Yes. Cheapflights offers flight deals from South Carolina to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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What are the cheapest airlines to fly from South Carolina to Durham one-way?
The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $137. However, be on the lookout for offers from JetBlue and American Airlines, as they are both options that can get you from South Carolina to Durham for a low price.
What are the most popular routes from South Carolina to Durham?
When deciding which route to take from South Carolina to Durham consider Charlotte Douglas - Raleigh-Durham, Greenville - Raleigh-Durham or Savannah/Hilton Head - Raleigh-Durham as they are the most popular.
Can I find deals for flights from South Carolina to Durham that include hotel bookings?
Yes. In addition to deals on South Carolina to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from South Carolina to Durham?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Durham.
Can I find deals for business class flights from South Carolina to Durham?
Yes. Cheapflights offers flight deals from South Carolina to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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Top airline flying from South Carolina to Durham

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$299	Average$510	FlexibilityNo cancel fee	On-time71%

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Find cheap flights from South Carolina to Durham with Cheapflights

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2. Select your favorite providers

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Find flight deals from South Carolina to Durham

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Related info for your journey

What are the cheapest airlines to fly from South Carolina to Durham one-way?

What are the most popular routes from South Carolina to Durham?

Can I find deals for flights from South Carolina to Durham that include hotel bookings?

How can I find direct flights from South Carolina to Durham?

Can I find deals for business class flights from South Carolina to Durham?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Durham

See prices for flight routes from nearby airports that may be better suited for you.

Complete your trip

Complete your trip to Durham by adding a car rental and/or hotel reservation to your travel itinerary.

Search flights from South Carolina to Durham by cabin class

Find flights from South Carolina to Durham, based on your preferred cabin class, be it economy, premium economy, business, or first class.

South Carolina and Durham flights

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Find cheap flights from South Carolina to Durham with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Find flight deals from South Carolina to Durham

Most accurate provider

Most trusted provider

Related info for your journey

What are the cheapest airlines to fly from South Carolina to Durham one-way?

What are the most popular routes from South Carolina to Durham?

Can I find deals for flights from South Carolina to Durham that include hotel bookings?

How can I find direct flights from South Carolina to Durham?

Can I find deals for business class flights from South Carolina to Durham?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Durham

See prices for flight routes from nearby airports that may be better suited for you.

Complete your trip

Complete your trip to Durham by adding a car rental and/or hotel reservation to your travel itinerary.

Search flights from South Carolina to Durham by cabin class

Find flights from South Carolina to Durham, based on your preferred cabin class, be it economy, premium economy, business, or first class.

South Carolina and Durham flights

Browse other South Carolina and Durham flight options. Last updated on September 28, 2026.

Popular flight searches

Check out other popular destinations found by fellow travelers in 2026

Find a return flight route from Durham

Find the right flight back to South Carolina after your stay in Durham

South Carolina to Durham flights

Consider these flights traveling from South Carolina to Durham.

Top airline flying from South Carolina to Durham

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