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Durham

$64+ Cheap flights from South Carolina to Durham, NC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/16. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — RDU
Apr 1 — Apr 81
Wed 4/1
Wed 4/8
1 adult, Economy
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Cheap flight deals from South Carolina to Durham

Cheapest flights from South Carolina to Durham
Explore the most affordable flight options available from South Carolina to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 2, 2026.

This Kiwi.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2111:12 am
CLT
-
RDU
1 stop5h 44m
Multiple Airlines
Wed 4/2210:54 am
RDU
-
CLT
1 stop5h 41m
Multiple Airlines
Deal found 2/26$134
This United Airlines deal was found by Cheapflights users on 2/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/296:00 am
CLT
-
RDU
1 stop3h 32m
United Airlines
Sun 4/56:00 am
RDU
-
CLT
1 stop3h 53m
United Airlines
Deal found 2/27$159
This Kiwi.com deal was found by Cheapflights users on 2/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/196:15 am
CHS
-
RDU
1 stop3h 52m
Breeze Airways
Mon 3/232:34 pm
RDU
-
CHS
1 stop7h 19m
Breeze Airways
Deal found 2/26$162
This Kiwi.com deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/69:32 pm
CLT
-
RDU
1 stop10h 24m
Multiple Airlines
Tue 5/269:42 pm
RDU
-
CLT
1 stop11h 35m
Multiple Airlines
Deal found 2/28$162
This Kiwi.com deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/68:05 pm
CLT
-
RDU
1 stop11h 51m
Multiple Airlines
Wed 5/2010:44 am
RDU
-
CLT
1 stop6h 21m
Multiple Airlines
Deal found 2/28$164
This Kiwi.com deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/75:41 pm
CLT
-
RDU
1 stop16h 18m
Frontier
Tue 5/269:42 pm
RDU
-
CLT
1 stop11h 35m
Frontier
Deal found 2/28$173
This Kiwi.com deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3112:04 pm
CHS
-
RDU
1 stop5h 25m
Spirit Airlines
Tue 4/76:25 pm
RDU
-
CHS
1 stop16h 44m
Spirit Airlines
Deal found 3/1$175
This Kiwi.com deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/75:41 pm
CLT
-
RDU
1 stop16h 18m
Multiple Airlines
Wed 5/2010:44 am
RDU
-
CLT
1 stop6h 21m
Multiple Airlines
Deal found 2/28$175
This Priceline deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1911:00 am
CHS
-
RDU
1 stop5h 46m
Multiple Airlines
Sun 8/2311:16 am
RDU
-
CHS
1 stop3h 50m
Multiple Airlines
Deal found 3/2$176
This Kiwi.com deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/69:32 pm
CLT
-
RDU
1 stop10h 24m
Multiple Airlines
Mon 5/258:29 pm
RDU
-
CLT
1 stop11h 29m
Multiple Airlines
Deal found 2/28$177
This Kiwi.com deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:09 pm
CLT
-
RDU
1 stop14h 49m
Multiple Airlines
Sun 4/1910:38 pm
RDU
-
CLT
1 stop9h 31m
Multiple Airlines
Deal found 2/28$180
This Kiwi.com deal was found by Cheapflights users on 2/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1412:04 pm
CHS
-
RDU
1 stop5h 25m
Multiple Airlines
Wed 4/152:34 pm
RDU
-
CHS
1 stop8h 02m
Multiple Airlines
Deal found 2/28$184

Find flight deals from South Carolina to Durham

Keep the following information in mind while searching for South Carolina to Durham flight deals. Data was last updated March 2, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$134
(Kiwi.com)

One-way from

$64
(Kiwi.com)
Provider with most accurate pricing for Myrtle Beach Intl-Raleigh-Durham flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Raleigh-Durham flights.
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From South Carolina to Durham
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One-way flight from South Carolina to Durham
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Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 2, 2026.
Use the filters below to find and compare flights from South Carolina to Durham that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlotteRaleigh

CLT - RDU

CLTRDU

Charlotte Douglas

Sun 3/29

6:00 am-9:32 am

1 stop3h 32m

Raleigh-Durham

Sun 4/5

6:00 am-9:53 am

1 stop3h 53m

$159

CharlotteRaleigh

CLT - RDU

CLTRDU

Charlotte Douglas

Thu 5/7

5:41 pm-9:59 am

1 stop16h 18m

Raleigh-Durham

Tue 5/26

9:42 pm-9:17 am

1 stop11h 35m

$173

CharlestonRaleigh

CHS - RDU

CHSRDU

Charleston

Fri 5/15

12:03 pm-12:15 am

2 stops12h 12m

Raleigh-Durham

Mon 5/18

3:46 pm-11:08 am

1 stop19h 22m

$185

CharlestonRaleigh

CHS - RDU

CHSRDU

Charleston

Thu 4/23

8:59 pm-9:56 am

1 stop12h 57m

Raleigh-Durham

Mon 4/27

9:32 pm-9:35 am

1 stop12h 03m

$189

CharlotteRaleigh

CLT - RDU

CLTRDU

Charlotte Douglas

Sat 3/28

9:28 pm-8:47 am

1 stop11h 19m

Raleigh-Durham

Fri 4/10

6:25 pm-1:52 pm

1 stop19h 27m

$208

CharlestonRaleigh

CHS - RDU

CHSRDU

Charleston

Wed 4/29

12:56 pm-8:00 pm

1 stop7h 04m

Raleigh-Durham

Thu 4/30

3:22 pm-7:59 pm

1 stop4h 37m

$217

CharlotteRaleigh

CLT - RDU

CLTRDU

Charlotte Douglas

Tue 4/21

11:09 am-4:20 pm

1 stop5h 11m

Raleigh-Durham

Wed 4/22

3:05 pm-9:15 pm

1 stop6h 10m

$219

CharlestonRaleigh

CHS - RDU

CHSRDU

Charleston

Sat 3/21

12:04 pm-5:29 pm

1 stop5h 25m

Raleigh-Durham

Mon 3/23

6:25 pm-11:09 am

1 stop16h 44m

$220

CharlotteRaleigh

CLT - RDU

CLTRDU

Charlotte Douglas

Fri 3/13

3:55 pm-9:56 pm

1 stop6h 01m

Raleigh-Durham

Mon 3/16

10:41 pm-8:03 am

1 stop9h 22m

$222

CharlestonRaleigh

CHS - RDU

CHSRDU

Charleston

Wed 3/25

12:04 pm-5:29 pm

1 stop5h 25m

Raleigh-Durham

Fri 3/27

8:18 pm-7:00 pm

1 stop22h 42m

$232

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/27

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from South Carolina to Durham

Have a flexible travel schedule? Discover the best time to fly to Durham from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Durham

What is the cheapest month to book a flight from South Carolina to Durham?

Currently, February is the cheapest month in which you can book a flight from South Carolina to Durham (average of $113). Flying from South Carolina to Durham in December is currently the most expensive (average of $398). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to DU8?

Find hourly flight availability from South Carolina to Durham. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 2, 2026.

Unlike in the morning, when flights are generally more expensive, you can save up to 52% on flights from South Carolina to Durham by exploring options for tickets in the evening.

What is the cheapest day to fly from South Carolina to Durham?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Durham. Price data was last updated on January 17, 2026.

Travelers seeking maximum savings on their South Carolina to Durham flight should consider departing on Thursday afternoons when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Durham?

    A quick flight from South Carolina to Durham can take about 3h 32m. United Airlines provides one of the quickest options available for as low as $159. South Carolina and Durham are separated by a distance of 129 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from South Carolina to Durham one-way?

    The cheapest airline one-way is Breeze Airways, with whom users have recently found tickets for as low as $65. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from South Carolina to Durham for a low price.

  • What are the most popular routes from South Carolina to Durham?

    When deciding which route to take from South Carolina to Durham consider Charlotte Douglas - Raleigh-Durham, Charleston - Raleigh-Durham or Greenville - Raleigh-Durham as they are the most popular.

  • Can I find deals for flights from South Carolina to Durham that include hotel bookings?

    Yes. In addition to deals on South Carolina to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Durham?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Durham.

  • Can I find deals for business class flights from South Carolina to Durham?

    Yes. Cheapflights offers flight deals from South Carolina to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Durham?

    Currently, February is the cheapest month in which you can book a flight from South Carolina to Durham (average of $113). Flying from South Carolina to Durham in December is currently the most expensive (average of $398). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Durham

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from South Carolina to Durham

Discover the top 2 airlines that operate flights from South Carolina to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 2, 2026.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$150Average$307FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$221Average$504FlexibilityNo cancel feeOn-time71%

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