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Durham

$39+ Cheap flights from South Carolina to Durham, NC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/18. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — RDU
Jan 22 — Jan 291
Thu 1/22
Thu 1/29
1 adult, Economy
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Cheap flight deals from South Carolina to Durham

Cheapest flights from South Carolina to Durham
Explore the most affordable flight options available from South Carolina to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 23, 2025.

This Kiwi.com deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2910:38 pmCLT - RDU
1 stop8h 58mMultiple Airlines
Tue 12/309:30 pmRDU - CLT
1 stop10h 30mMultiple Airlines
Deal found 12/22$255
This Kiwi.com deal was found by Cheapflights users on 12/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/249:34 pmCLT - RDU
1 stop10h 54mMultiple Airlines
Mon 12/299:47 pmRDU - CLT
1 stop10h 13mMultiple Airlines
Deal found 12/20$283
This Kiwi.com deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/249:34 pmCLT - RDU
1 stop10h 54mMultiple Airlines
Tue 12/309:30 pmRDU - CLT
1 stop16h 07mMultiple Airlines
Deal found 12/22$300
This Kiwi.com deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:19 pmCLT - RDU
1 stop12h 54mFrontier
Tue 12/309:30 pmRDU - CLT
1 stop16h 07mFrontier
Deal found 12/22$304
This Kiwi.com deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:19 pmCLT - RDU
1 stop12h 54mMultiple Airlines
Mon 12/299:47 pmRDU - CLT
1 stop10h 13mMultiple Airlines
Deal found 12/22$326
This Kiwi.com deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/289:33 pmCLT - RDU
1 stop10h 40mMultiple Airlines
Tue 12/309:30 pmRDU - CLT
1 stop10h 30mMultiple Airlines
Deal found 12/22$344
This American Airlines deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/242:31 pmCLT - RDU
Nonstop0h 55mAmerican Airlines
Sat 12/273:07 pmRDU - CLT
Nonstop1h 06mAmerican Airlines
Deal found 12/21$363
This Kiwi.com deal was found by Cheapflights users on 12/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/289:33 pmCLT - RDU
1 stop10h 40mMultiple Airlines
Mon 12/299:47 pmRDU - CLT
1 stop10h 13mMultiple Airlines
Deal found 12/22$367
This Kiwi.com deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/244:40 pmGSP - RDU
2 stops25h 48mMultiple Airlines
Wed 12/318:14 pmRDU - GSP
1 stop14h 39mMultiple Airlines
Deal found 12/21$371
This Kiwi.com deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/232:46 pmCHS - RDU
1 stop3h 45mBreeze Airways
Thu 12/257:11 pmRDU - CHS
1 stop3h 48mBreeze Airways
Deal found 12/21$377
This Delta deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/283:31 pmSAV - RDU
1 stop5h 17mDelta
Wed 12/318:05 amRDU - SAV
1 stop5h 16mDelta
Deal found 12/21$393
This Kiwi.com deal was found by Cheapflights users on 12/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/293:33 pmCHS - RDU
1 stop16h 41mMultiple Airlines
Tue 12/308:14 pmRDU - CHS
2 stops26h 45mMultiple Airlines
Deal found 12/21$443

Find flight deals from South Carolina to Durham

Keep the following information in mind while searching for South Carolina to Durham flight deals. Data was last updated December 23, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$129
(Kiwi.com)

One-way from

$39
(Kiwi.com)
Provider with most accurate pricing for Myrtle Beach Intl-Raleigh-Durham flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Raleigh-Durham flights.
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From South Carolina to Durham
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One-way flight from South Carolina to Durham
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Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
Use the filters below to find and compare flights from South Carolina to Durham that are best for you.

Fly from

South Carolina

Fly to

Durham

Route

Depart

Return

Price

CharlestonRaleigh

CHS - RDU

CHSRDU

Charleston

Thu 1/29

6:15 am-10:07 am

1 stop3h 52m

Raleigh-Durham

Wed 2/4

3:49 pm-5:36 pm

2 stops25h 47m

$129

SavannahRaleigh

SAV - RDU

SAVRDU

Savannah/Hilton Head

Thu 1/22

8:00 am-2:13 pm

1 stop6h 13m

Raleigh-Durham

Mon 1/26

3:08 pm-11:25 pm

1 stop8h 17m

$130

CharlotteRaleigh

CLT - RDU

CLTRDU

Charlotte Douglas

Wed 1/7

4:32 pm-7:53 am

1 stop15h 21m

Raleigh-Durham

Thu 1/15

10:11 pm-8:03 am

1 stop9h 52m

$142

CharlotteRaleigh

CLT - RDU

CLTRDU

Charlotte Douglas

Tue 1/20

6:01 pm-11:00 am

1 stop16h 59m

Raleigh-Durham

Tue 1/27

2:54 pm-10:40 am

1 stop19h 46m

$152

SavannahRaleigh

SAV - RDU

SAVRDU

Savannah/Hilton Head

Thu 1/15

8:00 am-2:13 pm

1 stop6h 13m

Raleigh-Durham

Mon 1/19

3:08 pm-11:25 pm

1 stop8h 17m

$153

CharlotteRaleigh

CLT - RDU

CLTRDU

Charlotte Douglas

Tue 1/6

8:46 pm-4:52 pm

1 stop20h 06m

Raleigh-Durham

Sat 1/10

6:00 am-7:46 pm

2 stops13h 46m

$162

CharlestonRaleigh

CHS - RDU

CHSRDU

Charleston

Tue 1/6

2:59 pm-4:52 pm

1 stop25h 53m

Raleigh-Durham

Sat 1/10

2:51 pm-10:30 am

1 stop19h 39m

$163

CharlotteRaleigh

CLT - RDU

CLTRDU

Charlotte Douglas

Tue 1/6

8:46 pm-4:52 pm

1 stop20h 06m

Raleigh-Durham

Sat 1/10

8:56 pm-4:54 pm

1 stop19h 58m

$165

SavannahRaleigh

SAV - RDU

SAVRDU

Savannah/Hilton Head

Fri 1/23

7:00 am-6:01 pm

2 stops11h 01m

Raleigh-Durham

Fri 1/30

3:08 pm-11:25 pm

1 stop8h 17m

$167

CharlotteRaleigh

CLT - RDU

CLTRDU

Charlotte Douglas

Sun 1/11

8:46 pm-2:48 pm

1 stop18h 02m

Raleigh-Durham

Fri 1/16

3:22 pm-7:49 pm

2 stops28h 27m

$168

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/22

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Durham

Have a flexible travel schedule? Discover the best time to fly to Durham from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Durham

What is the cheapest month to book a flight from South Carolina to Durham?

Currently, February is the cheapest month in which you can book a flight from South Carolina to Durham (average of $97). Flying from South Carolina to Durham in December is currently the most expensive (average of $398). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to DU8?

Find hourly flight availability from South Carolina to Durham. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 23, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 18% on flights from South Carolina to Durham by exploring options for tickets at noon.

What is the cheapest day to fly from South Carolina to Durham?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Durham. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their South Carolina to Durham flight should consider departing on Thursday afternoons when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Durham?

    A quick flight from South Carolina to Durham can take about 4h 09m. Frontier provides one of the quickest options available for as low as $229. South Carolina and Durham are separated by a distance of 205 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from South Carolina to Durham one-way?

    The cheapest airline one-way is Breeze Airways, with whom users have recently found tickets for as low as $36. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from South Carolina to Durham for a low price.

  • What are the most popular routes from South Carolina to Durham?

    When deciding which route to take from South Carolina to Durham consider Savannah/Hilton Head - Raleigh-Durham, Charleston - Raleigh-Durham or Charlotte Douglas - Raleigh-Durham as they are the most popular.

  • Can I find deals for flights from South Carolina to Durham that include hotel bookings?

    Yes. In addition to deals on South Carolina to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Durham?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Durham.

  • Can I find deals for business class flights from South Carolina to Durham?

    Yes. Cheapflights offers flight deals from South Carolina to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Durham?

    Currently, February is the cheapest month in which you can book a flight from South Carolina to Durham (average of $97). Flying from South Carolina to Durham in December is currently the most expensive (average of $398). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Durham

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from South Carolina to Durham

Discover the top 2 airlines that operate flights from South Carolina to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 23, 2025.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$95Average$229FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$221Average$442FlexibilityNo cancel feeOn-time71%

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