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Durham

$44+ Cheap flights from South Carolina to Durham, NC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/20. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — RDU
May 1 — May 81
Fri 5/1
Fri 5/8
1 adult, Economy
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Cheap flight deals from South Carolina to Durham

Cheapest flights from South Carolina to Durham
Explore the most affordable flight options available from South Carolina to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 1, 2026.

This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/278:09 pm
CLT
-
RDU
1 stop20h 47m
Multiple Airlines
Mon 5/410:51 pm
RDU
-
CLT
1 stop20h 01m
Multiple Airlines
Deal found 3/28$158
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1310:49 pm
CLT
-
RDU
1 stop10h 11m
Multiple Airlines
Thu 4/169:37 pm
RDU
-
CLT
1 stop11h 33m
Multiple Airlines
Deal found 3/30$159
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/169:31 am
CLT
-
RDU
1 stop6h 55m
Multiple Airlines
Sun 4/199:03 am
RDU
-
CLT
1 stop26h 42m
Multiple Airlines
Deal found 3/28$160
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1310:49 pm
CLT
-
RDU
1 stop13h 46m
Multiple Airlines
Fri 4/178:45 pm
RDU
-
CLT
1 stop11h 24m
Multiple Airlines
Deal found 3/29$164
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/169:31 am
CLT
-
RDU
1 stop6h 55m
Frontier
Sun 4/197:48 pm
RDU
-
CLT
1 stop13h 49m
Frontier
Deal found 3/29$167
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/29:54 pm
CLT
-
RDU
1 stop22h 31m
Multiple Airlines
Tue 5/126:05 pm
RDU
-
CLT
1 stop25h 08m
Multiple Airlines
Deal found 3/29$168
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1712:05 pm
CLT
-
RDU
1 stop7h 53m
Multiple Airlines
Sun 4/199:37 pm
RDU
-
CLT
1 stop16h 41m
Multiple Airlines
Deal found 3/30$173
This Kiwi.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:15 am
CHS
-
RDU
1 stop3h 52m
Multiple Airlines
Mon 4/2010:51 pm
RDU
-
CHS
1 stop9h 47m
Multiple Airlines
Deal found 4/1$184
This Kiwi.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/166:15 am
CHS
-
RDU
1 stop3h 52m
Multiple Airlines
Sun 4/197:48 pm
RDU
-
CHS
1 stop12h 55m
Multiple Airlines
Deal found 4/1$193
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/171:45 pm
SAV
-
RDU
1 stop7h 07m
Multiple Airlines
Fri 4/246:10 am
RDU
-
SAV
2 stops16h 38m
Multiple Airlines
Deal found 3/30$196
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1210:38 am
CHS
-
RDU
1 stop22h 43m
Multiple Airlines
Tue 5/198:01 pm
RDU
-
CHS
1 stop13h 37m
Multiple Airlines
Deal found 3/28$200
This Kiwi.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/42:53 pm
CHS
-
RDU
1 stop18h 07m
Multiple Airlines
Sat 6/67:52 pm
RDU
-
CHS
1 stop12h 46m
Multiple Airlines
Deal found 4/1$203

Find flight deals from South Carolina to Durham

Keep the following information in mind while searching for South Carolina to Durham flight deals. Data was last updated April 1, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$158
(Kiwi.com)

One-way from

$44
(CheapOair)
Provider with most accurate pricing for Myrtle Beach Intl-Raleigh-Durham flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Raleigh-Durham flights.
Search Deals
From South Carolina to Durham
Search Deals
One-way flight from South Carolina to Durham
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2026.
Use the filters below to find and compare flights from South Carolina to Durham that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvilleRaleigh

GSP - RDU

GSPRDU

Greenville

Mon 4/27

5:43 pm-3:04 pm

2 stops21h 21m

Raleigh-Durham

Mon 5/4

12:57 pm-7:38 pm

1 stop6h 41m

$210

CharlestonRaleigh

CHS - RDU

CHSRDU

Charleston

Tue 4/14

12:04 pm-5:29 pm

1 stop5h 25m

Raleigh-Durham

Fri 4/17

3:46 pm-11:08 am

1 stop19h 22m

$221

CharlestonRaleigh

CHS - RDU

CHSRDU

Charleston

Fri 4/17

3:21 pm-10:58 am

1 stop19h 37m

Raleigh-Durham

Sun 4/19

7:48 pm-8:43 am

1 stop12h 55m

$221

GreenvilleRaleigh

GSP - RDU

GSPRDU

Greenville

Fri 6/19

10:26 am-9:51 pm

1 stop11h 25m

Raleigh-Durham

Mon 6/22

10:36 pm-3:06 pm

1 stop16h 30m

$224

CharlestonRaleigh

CHS - RDU

CHSRDU

Charleston

Tue 5/5

10:18 am-5:20 pm

1 stop7h 02m

Raleigh-Durham

Wed 5/6

7:52 pm-8:38 am

1 stop12h 46m

$236

GreenvilleRaleigh

GSP - RDU

GSPRDU

Greenville

Mon 4/13

8:18 pm-9:00 am

1 stop12h 42m

Raleigh-Durham

Fri 4/17

12:57 pm-7:38 pm

1 stop6h 41m

$249

CharlestonRaleigh

CHS - RDU

CHSRDU

Charleston

Thu 4/23

6:15 am-10:07 am

1 stop3h 52m

Raleigh-Durham

Sat 4/25

7:31 pm-8:38 am

2 stops13h 07m

$261

SavannahRaleigh

SAV - RDU

SAVRDU

Savannah/Hilton Head

Fri 4/17

1:45 pm-8:52 pm

1 stop7h 07m

Raleigh-Durham

Tue 4/21

4:28 pm-7:29 pm

1 stop27h 01m

$264

CharlestonRaleigh

CHS - RDU

CHSRDU

Charleston

Sun 4/12

6:15 am-10:07 am

1 stop3h 52m

Raleigh-Durham

Wed 4/15

6:11 pm-8:38 am

1 stop14h 27m

$268

CharlestonRaleigh

CHS - RDU

CHSRDU

Charleston

Sun 5/31

6:45 am-10:36 am

1 stop3h 51m

Raleigh-Durham

Mon 6/1

10:36 pm-9:37 am

1 stop11h 01m

$268

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/1

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from South Carolina to Durham

Have a flexible travel schedule? Discover the best time to fly to Durham from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Durham

What is the cheapest time of day to fly from SC to DU8?

Find hourly flight availability from South Carolina to Durham. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 1, 2026.

Unlike in the morning, when flights are generally more expensive, you can save up to 52% on flights from South Carolina to Durham by exploring options for tickets in the evening.

What is the cheapest day to fly from South Carolina to Durham?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Durham. Price data was last updated on January 17, 2026.

Travelers seeking maximum savings on their South Carolina to Durham flight should consider departing on Thursday afternoons when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from South Carolina to Durham?

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Durham?

    A quick flight from South Carolina to Durham can take about 3h 50m. Spirit Airlines provides one of the quickest options available for as low as $295. South Carolina and Durham are separated by a distance of 294 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from South Carolina to Durham one-way?

    The cheapest airline one-way is Breeze Airways, with whom users have recently found tickets for as low as $65. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from South Carolina to Durham for a low price.

  • What are the most popular routes from South Carolina to Durham?

    When deciding which route to take from South Carolina to Durham consider Savannah/Hilton Head - Raleigh-Durham, Charlotte Douglas - Raleigh-Durham or Charleston - Raleigh-Durham as they are the most popular.

  • Can I find deals for flights from South Carolina to Durham that include hotel bookings?

    Yes. In addition to deals on South Carolina to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Durham?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Durham.

  • Can I find deals for business class flights from South Carolina to Durham?

    Yes. Cheapflights offers flight deals from South Carolina to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Durham

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from South Carolina to Durham

Discover the top 2 airlines that operate flights from South Carolina to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2026.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$150Average$307FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$221Average$482FlexibilityNo cancel feeOn-time71%

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