HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Durham

$49+ Cheap flights from South Carolina to Durham, NC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/20. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — RDU
Dec 13 — Dec 201
Sat 12/13
Sat 12/20
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from South Carolina to Durham with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from South Carolina to Durham

Cheapest flights from South Carolina to Durham
Explore the most affordable flight options available from South Carolina to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2710:22 amCLT - RDU
1 stop21h 53mMultiple Airlines
Mon 12/17:37 pmRDU - CLT
1 stop14h 13mMultiple Airlines
Deal found 11/12$130
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/88:10 pmCLT - RDU
1 stop23h 09mMultiple Airlines
Wed 12/3111:48 amRDU - CLT
1 stop8h 21mMultiple Airlines
Deal found 11/12$133
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/206:45 amCHS - RDU
1 stop3h 45mMultiple Airlines
Sun 11/238:45 pmRDU - CHS
1 stop12h 12mMultiple Airlines
Deal found 11/12$144
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/91:37 pmCLT - RDU
1 stop5h 42mMultiple Airlines
Tue 12/165:39 pmRDU - CLT
1 stop18h 25mMultiple Airlines
Deal found 11/11$144
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/89:20 pmCLT - RDU
2 stops26h 52mFrontier
Wed 12/3111:48 amRDU - CLT
1 stop8h 21mFrontier
Deal found 11/12$156
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/111:57 pmCLT - RDU
1 stop24h 24mMultiple Airlines
Tue 12/165:39 pmRDU - CLT
1 stop20h 23mMultiple Airlines
Deal found 11/11$165
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/157:30 amSAV - RDU
1 stop9h 25mMultiple Airlines
Wed 12/175:39 pmRDU - SAV
1 stop18h 49mMultiple Airlines
Deal found 11/12$169
This Mytrip deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/57:30 amSAV - RDU
1 stop9h 25mMultiple Airlines
Mon 12/85:50 pmRDU - SAV
1 stop5h 24mMultiple Airlines
Deal found 11/13$172
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/288:13 amCLT - RDU
1 stop6h 18mFrontier
Sat 11/291:08 pmRDU - CLT
1 stop5h 51mFrontier
Deal found 11/12$173
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/233:22 pmSAV - RDU
2 stops32h 51mMultiple Airlines
Mon 12/297:20 pmRDU - SAV
1 stop17h 08mMultiple Airlines
Deal found 11/11$190
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/251:54 pmCLT - RDU
1 stop5h 32mFrontier
Sat 11/291:08 pmRDU - CLT
1 stop5h 51mFrontier
Deal found 11/12$192
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/309:24 pmCLT - RDU
1 stop13h 28mFrontier
Tue 1/610:46 amRDU - CLT
1 stop5h 56mFrontier
Deal found 11/11$194

Cheap flight deals from South Carolina to Durham

Keep the following information in mind while searching for South Carolina to Durham flight deals. Data was last updated November 13, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$120
(Kissandfly.com)

One-way from

$49
(Breeze Airways)
Provider with most accurate pricing for Myrtle Beach Intl-Raleigh-Durham flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Raleigh-Durham flights.
Search Deals
From South Carolina to Durham
Search Deals
One-way flight from South Carolina to Durham
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from South Carolina to Durham that are best for you.

Fly from

South Carolina

Fly to

Durham

Route

Depart

Return

Price

CharlotteRaleigh

CLT - RDU

CLTRDU

Charlotte Douglas

Thu 11/27

10:22 am-8:15 am

1 stop21h 53m

Raleigh-Durham

Mon 12/1

7:37 pm-9:50 am

1 stop14h 13m

$130

CharlestonRaleigh

CHS - RDU

CHSRDU

Charleston

Thu 11/20

6:45 am-10:30 am

1 stop3h 45m

Raleigh-Durham

Sun 11/23

8:45 pm-8:57 am

1 stop12h 12m

$144

CharlotteRaleigh

CLT - RDU

CLTRDU

Charlotte Douglas

Tue 12/9

1:37 pm-7:19 pm

1 stop5h 42m

Raleigh-Durham

Tue 12/16

5:39 pm-12:04 pm

1 stop18h 25m

$144

CharlotteRaleigh

CLT - RDU

CLTRDU

Charlotte Douglas

Mon 12/8

9:20 pm-12:12 am

2 stops26h 52m

Raleigh-Durham

Wed 12/31

11:48 am-8:09 pm

1 stop8h 21m

$156

CharlestonRaleigh

CHS - RDU

CHSRDU

Charleston

Fri 1/9

1:19 pm-5:50 pm

1 stop4h 31m

Raleigh-Durham

Sun 1/11

10:47 am-2:36 pm

1 stop3h 49m

$157

CharlestonRaleigh

CHS - RDU

CHSRDU

Charleston

Mon 1/12

1:19 pm-5:50 pm

1 stop4h 31m

Raleigh-Durham

Wed 1/14

8:16 pm-8:33 am

1 stop12h 17m

$161

SavannahRaleigh

SAV - RDU

SAVRDU

Savannah/Hilton Head

Mon 12/15

7:30 am-4:55 pm

1 stop9h 25m

Raleigh-Durham

Wed 12/17

5:39 pm-12:28 pm

1 stop18h 49m

$169

CharlotteRaleigh

CLT - RDU

CLTRDU

Charlotte Douglas

Wed 2/4

6:01 pm-7:53 am

1 stop13h 52m

Raleigh-Durham

Mon 2/9

7:19 pm-6:51 pm

1 stop23h 32m

$171

SavannahRaleigh

SAV - RDU

SAVRDU

Savannah/Hilton Head

Fri 12/5

7:30 am-4:55 pm

1 stop9h 25m

Raleigh-Durham

Mon 12/8

5:50 pm-11:14 pm

1 stop5h 24m

$172

CharlotteRaleigh

CLT - RDU

CLTRDU

Charlotte Douglas

Fri 11/28

8:13 am-2:31 pm

1 stop6h 18m

Raleigh-Durham

Sat 11/29

1:08 pm-6:59 pm

1 stop5h 51m

$173

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/10

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from South Carolina to Durham

Have a flexible travel schedule? Discover the best time to fly to Durham from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Durham

What is the cheapest month to book a flight from South Carolina to Durham?

Currently, February is the cheapest month in which you can book a flight from South Carolina to Durham (average of $97). Flying from South Carolina to Durham in December is currently the most expensive (average of $336). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to DU8?

Find hourly flight availability from South Carolina to Durham. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 13, 2025.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 17% on flights from South Carolina to Durham by exploring options for tickets at noon.

What is the cheapest day to fly from South Carolina to Durham?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Durham. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their South Carolina to Durham flight should consider departing on Thursday afternoons when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Durham?

    A quick flight from South Carolina to Durham can take about 4h 31m. Frontier provides one of the quickest options available for as low as $157. South Carolina and Durham are separated by a distance of 218 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from South Carolina to Durham one-way?

    The cheapest airline one-way is Breeze Airways, with whom users have recently found tickets for as low as $49. However, be on the lookout for offers from Frontier and Spirit Airlines, as they are both options that can get you from South Carolina to Durham for a low price.

  • What are the most popular routes from South Carolina to Durham?

    When deciding which route to take from South Carolina to Durham consider Charlotte Douglas - Raleigh-Durham, Savannah/Hilton Head - Raleigh-Durham or Charleston - Raleigh-Durham as they are the most popular.

  • Can I find deals for flights from South Carolina to Durham that include hotel bookings?

    Yes. In addition to deals on South Carolina to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Durham?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Durham.

  • Can I find deals for business class flights from South Carolina to Durham?

    Yes. Cheapflights offers flight deals from South Carolina to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Durham?

    Currently, February is the cheapest month in which you can book a flight from South Carolina to Durham (average of $97). Flying from South Carolina to Durham in December is currently the most expensive (average of $336). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Durham

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Charlotte flights
John F Kennedy Intl to Raleigh flights
Newark to Charlotte flights
Boston to Charlotte flights
LaGuardia to Charlotte flights
LaGuardia to Raleigh flights
Newark to Raleigh flights
O'Hare Intl to Charlotte flights
Dallas/Fort Worth to Charlotte flights
Boston to Raleigh flights
Denver to Charlotte flights
O'Hare Intl to Raleigh flights
Dallas/Fort Worth to Raleigh flights
Denver to Raleigh flights
San Francisco to Raleigh flights
Atlanta to Raleigh flights
Los Angeles to Raleigh flights
Hobby to Charlotte flights
Los Angeles to Charlotte flights
George Bush Intcntl to Charlotte flights
Dulles Intl to Charlotte flights
Seattle to Charlotte flights
Philadelphia to Charlotte flights
San Francisco to Charlotte flights
Baltimore to Charlotte flights
O'Hare Intl to Knoxville flights
Newark to Myrtle Beach flights
Miami to Raleigh flights
Providence to Raleigh flights
Hobby to Raleigh flights
John F Kennedy Intl to Myrtle Beach flights
Philadelphia to Raleigh flights
John F Kennedy Intl to Norfolk flights
Tampa to Raleigh flights
LaGuardia to Greensboro flights
LaGuardia to Myrtle Beach flights
Newark to Greensboro flights
George Bush Intcntl to Knoxville flights
Reagan-National to Charlotte flights
Minneapolis to Raleigh flights
Minneapolis to Charlotte flights
Seattle to Raleigh flights
John F Kennedy Intl to Knoxville flights
Dallas/Fort Worth to Knoxville flights
Austin to Raleigh flights
LaGuardia to Norfolk flights
Hobby to Knoxville flights
Fort Lauderdale to Charlotte flights
Detroit to Charlotte flights
Love Field to Charlotte flights

Top 2 airlines flying from South Carolina to Durham

Discover the top 2 airlines that operate flights from South Carolina to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$95Average$217FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$247Average$489FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.