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Durham

$35+ Cheap flights from South Carolina to Durham, NC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/26. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — RDU
Mar 11 — Mar 181
Wed 3/11
Wed 3/18
1 adult, Economy
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Cheap flight deals from South Carolina to Durham

Cheapest flights from South Carolina to Durham
Explore the most affordable flight options available from South Carolina to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 9, 2026.

This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/188:43 am
CLT
-
RDU
1 stop11h 47m
Frontier
Wed 2/252:53 pm
RDU
-
CLT
1 stop17h 05m
Frontier
Deal found 2/5$133
This Mytrip deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/249:18 am
CLT
-
RDU
1 stop8h 11m
Spirit Airlines
Tue 4/146:25 pm
RDU
-
CLT
1 stop5h 28m
Spirit Airlines
Deal found 2/8$139
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/195:00 pm
CHS
-
RDU
1 stop25h 52m
Multiple Airlines
Mon 2/236:14 pm
RDU
-
CHS
1 stop21h 51m
Multiple Airlines
Deal found 2/5$141
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/249:18 am
CLT
-
RDU
1 stop8h 11m
Spirit Airlines
Tue 3/316:25 pm
RDU
-
CLT
1 stop5h 28m
Spirit Airlines
Deal found 2/7$141
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/188:43 am
CLT
-
RDU
1 stop11h 47m
Multiple Airlines
Wed 2/256:25 am
RDU
-
CLT
2 stops17h 31m
Multiple Airlines
Deal found 2/5$144
This Kiwi.com deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/205:00 pm
CHS
-
RDU
1 stop24h 11m
Multiple Airlines
Mon 2/236:14 pm
RDU
-
CHS
1 stop21h 51m
Multiple Airlines
Deal found 2/5$145
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/79:21 am
CLT
-
RDU
1 stop7h 50m
Multiple Airlines
Sun 3/810:38 pm
RDU
-
CLT
1 stop18h 25m
Multiple Airlines
Deal found 2/7$149
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/89:07 pm
CLT
-
RDU
1 stop20h 04m
Multiple Airlines
Sun 3/1510:38 pm
RDU
-
CLT
1 stop9h 20m
Multiple Airlines
Deal found 2/7$151
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/173:12 pm
CLT
-
RDU
1 stop22h 46m
Frontier
Thu 2/199:59 pm
RDU
-
CLT
1 stop9h 59m
Frontier
Deal found 2/6$153
This CheapOair deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/195:00 pm
CHS
-
RDU
1 stop24h 11m
Spirit Airlines
Mon 2/236:08 pm
RDU
-
CHS
1 stop21h 57m
Spirit Airlines
Deal found 2/5$157
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/149:18 am
CLT
-
RDU
1 stop8h 11m
Multiple Airlines
Sun 3/1510:38 pm
RDU
-
CLT
1 stop9h 20m
Multiple Airlines
Deal found 2/6$157
This Kiwi.com deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/185:00 pm
CHS
-
RDU
1 stop24h 11m
Spirit Airlines
Mon 2/236:08 pm
RDU
-
CHS
1 stop21h 57m
Spirit Airlines
Deal found 2/4$159

Find flight deals from South Carolina to Durham

Keep the following information in mind while searching for South Carolina to Durham flight deals. Data was last updated February 9, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$133
(Kiwi.com)

One-way from

$35
(Kiwi.com)
Provider with most accurate pricing for Myrtle Beach Intl-Raleigh-Durham flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Raleigh-Durham flights.
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From South Carolina to Durham
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One-way flight from South Carolina to Durham
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Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 9, 2026.
Use the filters below to find and compare flights from South Carolina to Durham that are best for you.

Fly from

South Carolina

Fly to

Durham

Route

Depart

Return

Price

CharlotteRaleigh

CLT - RDU

CLTRDU

Charlotte Douglas

Mon 3/9

9:28 pm-8:58 am

1 stop11h 30m

Raleigh-Durham

Mon 3/16

10:41 pm-8:03 am

1 stop9h 22m

$133

CharlotteRaleigh

CLT - RDU

CLTRDU

Charlotte Douglas

Tue 3/10

1:59 pm-9:53 pm

1 stop7h 54m

Raleigh-Durham

Tue 3/17

6:25 pm-11:53 pm

1 stop5h 28m

$133

CharlotteRaleigh

CLT - RDU

CLTRDU

Charlotte Douglas

Wed 2/18

8:43 am-8:30 pm

1 stop11h 47m

Raleigh-Durham

Wed 2/25

2:53 pm-7:58 am

1 stop17h 05m

$133

CharlotteRaleigh

CLT - RDU

CLTRDU

Charlotte Douglas

Tue 3/24

9:18 am-5:29 pm

1 stop8h 11m

Raleigh-Durham

Tue 4/14

6:25 pm-11:53 pm

1 stop5h 28m

$139

CharlotteRaleigh

CLT - RDU

CLTRDU

Charlotte Douglas

Wed 5/6

6:30 am-2:42 pm

1 stop8h 12m

Raleigh-Durham

Sat 5/16

11:53 am-6:23 pm

1 stop6h 30m

$140

CharlotteRaleigh

CLT - RDU

CLTRDU

Charlotte Douglas

Tue 3/24

9:18 am-5:29 pm

1 stop8h 11m

Raleigh-Durham

Tue 3/31

6:25 pm-11:53 pm

1 stop5h 28m

$141

CharlotteRaleigh

CLT - RDU

CLTRDU

Charlotte Douglas

Sun 3/8

9:07 pm-5:11 pm

1 stop20h 04m

Raleigh-Durham

Sun 3/15

10:38 pm-7:58 am

1 stop9h 20m

$151

CharlotteRaleigh

CLT - RDU

CLTRDU

Charlotte Douglas

Tue 2/17

3:12 pm-1:58 pm

1 stop22h 46m

Raleigh-Durham

Thu 2/19

9:59 pm-7:58 am

1 stop9h 59m

$153

CharlestonRaleigh

CHS - RDU

CHSRDU

Charleston

Wed 2/25

5:00 pm-5:11 pm

1 stop24h 11m

Raleigh-Durham

Sat 2/28

6:08 pm-4:05 pm

1 stop21h 57m

$157

CharlotteRaleigh

CLT - RDU

CLTRDU

Charlotte Douglas

Sat 3/14

9:18 am-5:29 pm

1 stop8h 11m

Raleigh-Durham

Sun 3/15

10:38 pm-7:58 am

1 stop9h 20m

$157

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/8

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Durham

Have a flexible travel schedule? Discover the best time to fly to Durham from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Durham

What is the cheapest month to book a flight from South Carolina to Durham?

Currently, February is the cheapest month in which you can book a flight from South Carolina to Durham (average of $110). Flying from South Carolina to Durham in December is currently the most expensive (average of $398). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to DU8?

Find hourly flight availability from South Carolina to Durham. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 9, 2026.

Unlike in the morning, when flights are generally more expensive, you can save up to 52% on flights from South Carolina to Durham by exploring options for tickets in the evening.

What is the cheapest day to fly from South Carolina to Durham?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Durham. Price data was last updated on January 17, 2026.

Travelers seeking maximum savings on their South Carolina to Durham flight should consider departing on Thursday afternoons when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Durham?

    A quick flight from South Carolina to Durham can take about 6h 31m. Frontier provides one of the quickest options available for as low as $183. South Carolina and Durham are separated by a distance of 294 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from South Carolina to Durham one-way?

    The cheapest airline one-way is Breeze Airways, with whom users have recently found tickets for as low as $36. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from South Carolina to Durham for a low price.

  • What are the most popular routes from South Carolina to Durham?

    When deciding which route to take from South Carolina to Durham consider Charlotte Douglas - Raleigh-Durham, Charleston - Raleigh-Durham or Greenville - Raleigh-Durham as they are the most popular.

  • Can I find deals for flights from South Carolina to Durham that include hotel bookings?

    Yes. In addition to deals on South Carolina to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Durham?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Durham.

  • Can I find deals for business class flights from South Carolina to Durham?

    Yes. Cheapflights offers flight deals from South Carolina to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Durham?

    Currently, February is the cheapest month in which you can book a flight from South Carolina to Durham (average of $110). Flying from South Carolina to Durham in December is currently the most expensive (average of $398). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Durham

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from South Carolina to Durham

Discover the top 2 airlines that operate flights from South Carolina to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 9, 2026.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$102Average$247FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$221Average$489FlexibilityNo cancel feeOn-time71%

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