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Durham

$42+ Cheap flights from South Carolina to Durham, NC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/15. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — RDU
Feb 25 — Mar 41
Wed 2/25
Wed 3/4
1 adult, Economy
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Cheap flight deals from South Carolina to Durham

Cheapest flights from South Carolina to Durham
Explore the most affordable flight options available from South Carolina to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 26, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/105:54 pm
CLT
-
RDU
1 stop24h 58m
Frontier
Sat 2/149:25 pm
RDU
-
CLT
1 stop10h 33m
Frontier
Deal found 1/26$132
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/289:21 am
CLT
-
RDU
1 stop7h 50m
Multiple Airlines
Sun 3/110:59 pm
RDU
-
CLT
1 stop11h 18m
Multiple Airlines
Deal found 1/26$144
This Kiwi.com deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/99:56 pm
CLT
-
RDU
1 stop16h 02m
Multiple Airlines
Fri 2/136:14 pm
RDU
-
CLT
1 stop25h 58m
Multiple Airlines
Deal found 1/24$148
This Kiwi.com deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:35 pm
CHS
-
RDU
2 stops22h 36m
Spirit Airlines
Tue 3/36:08 pm
RDU
-
CHS
1 stop21h 57m
Spirit Airlines
Deal found 1/24$149
This Kiwi.com deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/235:00 pm
CHS
-
RDU
1 stop24h 11m
Spirit Airlines
Mon 3/26:08 pm
RDU
-
CHS
1 stop21h 57m
Spirit Airlines
Deal found 1/24$153
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2010:20 pm
CLT
-
RDU
1 stop9h 32m
Frontier
Sun 2/2210:59 pm
RDU
-
CLT
1 stop7h 50m
Frontier
Deal found 1/26$153
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/95:05 pm
CHS
-
RDU
1 stop21h 37m
Multiple Airlines
Thu 2/126:05 am
RDU
-
CHS
2 stops11h 35m
Multiple Airlines
Deal found 1/26$169
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/42:46 pm
CLT
-
RDU
1 stop5h 44m
Multiple Airlines
Thu 3/59:05 pm
RDU
-
CLT
1 stop10h 58m
Multiple Airlines
Deal found 1/25$171
This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/103:01 pm
CHS
-
RDU
1 stop5h 29m
Multiple Airlines
Sat 2/149:25 pm
RDU
-
CHS
1 stop11h 13m
Multiple Airlines
Deal found 1/25$172
This Kiwi.com deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/1311:12 am
CLT
-
RDU
1 stop9h 20m
Multiple Airlines
Sun 2/1510:59 pm
RDU
-
CLT
1 stop7h 50m
Multiple Airlines
Deal found 1/24$172
This Kiwi.com deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/2210:50 am
CLT
-
RDU
2 stops34h 32m
Frontier
Sun 3/110:59 pm
RDU
-
CLT
1 stop7h 50m
Frontier
Deal found 1/24$174
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/106:00 am
CLT
-
RDU
2 stops18h 10m
Multiple Airlines
Sat 2/149:25 pm
RDU
-
CLT
1 stop10h 33m
Multiple Airlines
Deal found 1/26$180

Find flight deals from South Carolina to Durham

Keep the following information in mind while searching for South Carolina to Durham flight deals. Data was last updated January 26, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$132
(Kiwi.com)

One-way from

$42
(Kiwi.com)
Provider with most accurate pricing for Myrtle Beach Intl-Raleigh-Durham flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Raleigh-Durham flights.
Search Deals
From South Carolina to Durham
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One-way flight from South Carolina to Durham
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Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 26, 2026.
Use the filters below to find and compare flights from South Carolina to Durham that are best for you.

Fly from

South Carolina

Fly to

Durham

Route

Depart

Return

Price

CharlotteRaleigh

CLT - RDU

CLTRDU

Charlotte Douglas

Sat 2/28

9:21 am-5:11 pm

1 stop7h 50m

Raleigh-Durham

Sun 3/1

10:59 pm-10:17 am

1 stop11h 18m

$144

CharlestonRaleigh

CHS - RDU

CHSRDU

Charleston

Fri 2/27

6:35 pm-5:11 pm

2 stops22h 36m

Raleigh-Durham

Tue 3/3

6:08 pm-4:05 pm

1 stop21h 57m

$149

CharlotteRaleigh

CLT - RDU

CLTRDU

Charlotte Douglas

Fri 2/20

10:20 pm-7:52 am

1 stop9h 32m

Raleigh-Durham

Sun 2/22

10:59 pm-6:49 am

1 stop7h 50m

$153

CharlestonRaleigh

CHS - RDU

CHSRDU

Charleston

Mon 2/9

5:05 pm-2:42 pm

1 stop21h 37m

Raleigh-Durham

Thu 2/12

6:05 am-5:40 pm

2 stops11h 35m

$169

CharlestonRaleigh

CHS - RDU

CHSRDU

Charleston

Mon 2/23

6:35 pm-12:10 am

2 stops29h 35m

Raleigh-Durham

Mon 3/2

6:08 pm-4:05 pm

1 stop21h 57m

$169

CharlotteRaleigh

CLT - RDU

CLTRDU

Charlotte Douglas

Wed 3/4

2:46 pm-8:30 pm

1 stop5h 44m

Raleigh-Durham

Thu 3/5

9:05 pm-8:03 am

1 stop10h 58m

$171

CharlotteRaleigh

CLT - RDU

CLTRDU

Charlotte Douglas

Fri 2/13

11:12 am-8:32 pm

1 stop9h 20m

Raleigh-Durham

Sun 2/15

10:59 pm-6:49 am

1 stop7h 50m

$172

CharlotteRaleigh

CLT - RDU

CLTRDU

Charlotte Douglas

Sun 2/22

10:50 am-9:22 pm

2 stops34h 32m

Raleigh-Durham

Sun 3/1

10:59 pm-6:49 am

1 stop7h 50m

$174

CharlotteRaleigh

CLT - RDU

CLTRDU

Charlotte Douglas

Sun 2/22

5:49 pm-8:37 am

1 stop14h 48m

Raleigh-Durham

Sun 3/1

10:59 pm-10:17 am

1 stop11h 18m

$181

CharlotteRaleigh

CLT - RDU

CLTRDU

Charlotte Douglas

Mon 2/9

1:24 pm-12:11 am

2 stops10h 47m

Raleigh-Durham

Fri 2/13

6:14 pm-8:12 pm

1 stop25h 58m

$183

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Durham

Have a flexible travel schedule? Discover the best time to fly to Durham from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Durham

What is the cheapest month to book a flight from South Carolina to Durham?

Currently, February is the cheapest month in which you can book a flight from South Carolina to Durham (average of $97). Flying from South Carolina to Durham in December is currently the most expensive (average of $398). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to DU8?

Find hourly flight availability from South Carolina to Durham. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 26, 2026.

Unlike in the morning, when flights are generally more expensive, you can save up to 52% on flights from South Carolina to Durham by exploring options for tickets in the evening.

What is the cheapest day to fly from South Carolina to Durham?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Durham. Price data was last updated on January 17, 2026.

Travelers seeking maximum savings on their South Carolina to Durham flight should consider departing on Thursday afternoons when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Durham?

    A quick flight from South Carolina to Durham can take about 3h 12m. Spirit Airlines provides one of the quickest options available for as low as $255. South Carolina and Durham are separated by a distance of 205 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from South Carolina to Durham one-way?

    The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $136. However, be on the lookout for offers from Frontier and JetBlue, as they are both options that can get you from South Carolina to Durham for a low price.

  • What are the most popular routes from South Carolina to Durham?

    When deciding which route to take from South Carolina to Durham consider Charlotte Douglas - Raleigh-Durham, Savannah/Hilton Head - Raleigh-Durham or Charleston - Raleigh-Durham as they are the most popular.

  • Can I find deals for flights from South Carolina to Durham that include hotel bookings?

    Yes. In addition to deals on South Carolina to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Durham?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Durham.

  • Can I find deals for business class flights from South Carolina to Durham?

    Yes. Cheapflights offers flight deals from South Carolina to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Durham?

    Currently, February is the cheapest month in which you can book a flight from South Carolina to Durham (average of $97). Flying from South Carolina to Durham in December is currently the most expensive (average of $398). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Durham

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from South Carolina to Durham

Discover the top 2 airlines that operate flights from South Carolina to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 26, 2026.
AirlineCheapestAverageFlexibilityOn-time
Breeze AirwaysCheapest$102Average$247FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$221Average$489FlexibilityNo cancel feeOn-time71%

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