What are the cheapest airlines to fly from Durham to South Carolina one-way?

For one-way options, check prices for Breeze Airways. According to our data, you can fly for as low as $56. Users have also found prices from $127 and $177 on Delta and American Airlines, respectively.

In terms of precipitation, rainfall in South Carolina ranges from 3.0 - 6.5 inches per month. July is typically the wettest month, when rainfall can reach 6.5 in. November is typically the driest time to visit South Carolina when rainfall is around 3.0 in.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 44.6 F).

What are the most popular routes from Durham to South Carolina?

When deciding which route to take from Durham to South Carolina consider Raleigh-Durham - Greenville, Raleigh-Durham - Savannah/Hilton Head or Raleigh-Durham - Charlotte Douglas as they are the most popular.

What is the cheapest time of day to fly from DU8 to SC?

When flying from Durham to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Can I find deals for flights from Durham to South Carolina that include hotel bookings?

Yes. In addition to deals on Durham to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Durham to South Carolina?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to South Carolina.

Can I find deals for business class flights from Durham to South Carolina?

Yes. Cheapflights offers flight deals from Durham to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

Find Cheap Flights from Durham to South Carolina

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Reviews of airlines servicing South Carolina

Get a feel of what it's like to fly with Delta and American Airlines from Durham to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.8

Good

8,678 reviews

Reviews

1 / 20

6.0

Good

Ellen,Oct 2026

GRR - ATL

The flight was delayed more then 30 minutes after I hurried and stressed to get to my connecting gate in Atlanta.

Delta

7.8

Good

8,678 reviews

Delta

7.8

Good

8,678 reviews

Reviews

1 / 20

6.0

Good

Ellen,Oct 2026

GRR - ATL

The flight was delayed more then 30 minutes after I hurried and stressed to get to my connecting gate in Atlanta.

American Airlines

7.0

Good

12,194 reviews

Delta

7.8

Good

8,678 reviews

Reviews

1 / 20

6.0

Good

Ellen,Oct 2026

GRR - ATL

The flight was delayed more then 30 minutes after I hurried and stressed to get to my connecting gate in Atlanta.

Related info for your journey

What are the cheapest airlines to fly from Durham to South Carolina one-way?
For one-way options, check prices for Breeze Airways. According to our data, you can fly for as low as $56. Users have also found prices from $127 and $177 on Delta and American Airlines, respectively.
What are the most popular routes from Durham to South Carolina?
When deciding which route to take from Durham to South Carolina consider Raleigh-Durham - Greenville, Raleigh-Durham - Savannah/Hilton Head or Raleigh-Durham - Charlotte Douglas as they are the most popular.
Can I find deals for flights from Durham to South Carolina that include hotel bookings?
Yes. In addition to deals on Durham to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Durham to South Carolina?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to South Carolina.
Can I find deals for business class flights from Durham to South Carolina?
Yes. Cheapflights offers flight deals from Durham to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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Top 2 airlines flying from Durham to South Carolina

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$349	Average$484	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$384	Average$482	FlexibilityNo cancel fee	On-timeN/A

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Find cheap flights from Durham to South Carolina with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Find flight deals from Durham to South Carolina

Most accurate provider

Most trusted provider

Reviews of airlines servicing South Carolina

Get a feel of what it's like to fly with Delta and American Airlines from Durham to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

What are the cheapest airlines to fly from Durham to South Carolina one-way?

What are the most popular routes from Durham to South Carolina?

Can I find deals for flights from Durham to South Carolina that include hotel bookings?

How can I find direct flights from Durham to South Carolina?

Can I find deals for business class flights from Durham to South Carolina?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Durham to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Complete your trip

Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.

Search flights from Durham to South Carolina by cabin class

Find flights from Durham to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Durham and South Carolina flights

Browse other Durham and South Carolina flight options. Last updated on October 25, 2026.

Popular flight searches

Check out other popular destinations found by fellow travelers in 2026

Find a return flight route from South Carolina

Find the right flight back to Durham after your stay in South Carolina

Durham to South Carolina flights

Consider these flights traveling from Durham to South Carolina.

Top 2 airlines flying from Durham to South Carolina

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Cheap flights from Durham, NC to South Carolina

Find cheap flights from Durham to South Carolina with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Find flight deals from Durham to South Carolina

Most accurate provider

Most trusted provider

Reviews of airlines servicing South Carolina

Get a feel of what it's like to fly with Delta and American Airlines from Durham to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

What are the cheapest airlines to fly from Durham to South Carolina one-way?

What are the most popular routes from Durham to South Carolina?

Can I find deals for flights from Durham to South Carolina that include hotel bookings?

How can I find direct flights from Durham to South Carolina?

Can I find deals for business class flights from Durham to South Carolina?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Durham to South Carolina

See prices for flight routes from nearby airports that may be better suited for you.

Complete your trip

Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.

Search flights from Durham to South Carolina by cabin class

Find flights from Durham to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Durham and South Carolina flights

Browse other Durham and South Carolina flight options. Last updated on October 25, 2026.

Popular flight searches

Check out other popular destinations found by fellow travelers in 2026

Find a return flight route from South Carolina

Find the right flight back to Durham after your stay in South Carolina

Durham to South Carolina flights

Consider these flights traveling from Durham to South Carolina.

Top 2 airlines flying from Durham to South Carolina

100% Free

Book with Flexibility

Travel Smart