$90+ Cheap flights from Durham, NC to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/11. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — CHS
Jul 15 — Jul 221
Round-trip
1 adult, Economy
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Find cheap flights from Durham to South Carolina with Cheapflights
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Cheapest flights from Durham to South CarolinaExplore the most affordable flight options available from Durham to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 15, 2026.
Explore the most affordable flight options available from Durham to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 15, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/218:56 am
RDU
- CLT
1 stop12h 11m
Frontier
Tue 7/286:48 pm
CLT
- RDU
1 stop22h 41m
Frontier
Deal found 6/15![Frontier logo]()
$197
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2111:55 am
RDU
- CLT
2 stops9h 12m
Multiple Airlines
Tue 7/286:48 pm
CLT
- RDU
1 stop22h 41m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$201
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:14 pm
RDU
- CLT
1 stop22h 58m
Frontier
Wed 7/156:41 pm
CLT
- RDU
1 stop22h 28m
Frontier
Deal found 6/10![Frontier logo]()
$208
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:14 pm
RDU
- CLT
1 stop22h 58m
Multiple Airlines
Wed 7/156:41 pm
CLT
- RDU
2 stops15h 04m
Multiple Airlines
Deal found 6/10![Multiple Airlines logo]()
$214
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/67:32 pm
RDU
- CHS
1 stop13h 06m
Multiple Airlines
Thu 7/92:53 pm
CHS
- RDU
1 stop18h 07m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/89:48 pm
RDU
- CHS
1 stop10h 50m
Breeze Airways
Thu 8/136:45 am
CHS
- RDU
1 stop3h 51m
Breeze Airways
Deal found 6/12![Breeze Airways logo]()
$217
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/49:07 pm
RDU
- CHS
1 stop11h 36m
Breeze Airways
Sun 9/66:45 am
CHS
- RDU
1 stop3h 51m
Breeze Airways
Deal found 6/13![Breeze Airways logo]()
$218
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/611:16 am
RDU
- CHS
1 stop3h 50m
Breeze Airways
Sun 8/96:45 am
CHS
- RDU
1 stop3h 51m
Breeze Airways
Deal found 6/12![Breeze Airways logo]()
$220
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/188:06 pm
RDU
- CHS
1 stop12h 32m
Multiple Airlines
Wed 7/224:04 pm
CHS
- RDU
1 stop16h 56m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$221
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:45 am
RDU
- CLT
1 stop6h 00m
Southwest
Tue 8/258:30 am
CLT
- RDU
1 stop6h 25m
Southwest
Deal found 6/10![Southwest logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/89:48 pm
RDU
- CHS
1 stop10h 50m
Breeze Airways
Fri 7/109:44 pm
CHS
- RDU
1 stop11h 14m
Breeze Airways
Deal found 6/11![Breeze Airways logo]()
$233
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/298:06 pm
RDU
- CHS
1 stop12h 32m
Multiple Airlines
Mon 8/319:33 pm
CHS
- RDU
1 stop11h 22m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$236
Best flights from Durham to South CarolinaDiscover carefully curated flight deals from Durham to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 15, 2026.
Discover carefully curated flight deals from Durham to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 15, 2026.
This Breeze Airways deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/911:16 am
RDU
- CHS
1 stop3h 50m
Breeze Airways
Thu 7/166:45 am
CHS
- RDU
1 stop3h 51m
Breeze Airways
Deal found 6/11![Breeze Airways logo]()
$221
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/188:06 pm
RDU
- CHS
1 stop12h 32m
Multiple Airlines
Wed 7/224:04 pm
CHS
- RDU
1 stop16h 56m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$221
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:45 am
RDU
- CLT
1 stop6h 00m
Southwest
Tue 8/258:30 am
CLT
- RDU
1 stop6h 25m
Southwest
Deal found 6/10![Southwest logo]()
$228
This JetBlue deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1811:00 am
RDU
- SAV
1 stop7h 22m
JetBlue
Tue 7/2110:56 am
SAV
- RDU
1 stop5h 51m
JetBlue
Deal found 6/13![JetBlue logo]()
$263
This Delta deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/811:15 am
RDU
- HHH
1 stop4h 14m
Delta
Tue 7/1412:11 pm
HHH
- RDU
1 stop4h 09m
Delta
Deal found 6/13![Delta logo]()
$291
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/55:01 am
RDU
- HHH
1 stop6h 16m
American Airlines
Tue 7/1411:47 am
HHH
- RDU
1 stop3h 38m
American Airlines
Deal found 6/10![American Airlines logo]()
$301
This United Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2210:32 am
RDU
- GSP
1 stop3h 48m
United Airlines
Sat 7/257:40 pm
GSP
- RDU
1 stop3h 49m
United Airlines
Deal found 6/15![United Airlines logo]()
$310
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:15 am
RDU
- SAV
2 stops17h 09m
Multiple Airlines
Thu 8/1310:05 am
SAV
- RDU
1 stop7h 10m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$262
This JetBlue deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2510:59 am
RDU
- SAV
1 stop7h 21m
JetBlue
Wed 8/2610:55 am
SAV
- RDU
1 stop5h 51m
JetBlue
Deal found 6/13![JetBlue logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/101:27 pm
RDU
- MYR
2 stops19h 41m
Breeze Airways
Tue 11/1710:45 am
MYR
- RDU
1 stop10h 42m
Breeze Airways
Deal found 6/14![Breeze Airways logo]()
$276
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1310:34 pm
RDU
- MYR
1 stop15h 32m
Multiple Airlines
Mon 8/173:31 pm
MYR
- RDU
2 stops19h 44m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$266
This American Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:01 am
RDU
- GSP
1 stop5h 07m
American Airlines
Sat 7/47:00 am
GSP
- RDU
1 stop3h 23m
American Airlines
Deal found 6/14![American Airlines logo]()
$307
This Breeze Airways deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/211:16 am
RDU
- CHS
1 stop3h 50m
Breeze Airways
Thu 7/96:45 am
CHS
- RDU
1 stop3h 51m
Breeze Airways
Deal found 6/11![Breeze Airways logo]()
$291
This Southwest deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/178:40 am
RDU
- GSP
2 stops9h 35m
Southwest
Tue 7/211:50 pm
GSP
- RDU
1 stop3h 40m
Southwest
Deal found 6/14![Southwest logo]()
$323
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:00 am
RDU
- GSP
1 stop3h 55m
United Airlines
Wed 7/157:40 pm
GSP
- RDU
1 stop4h 04m
United Airlines
Deal found 6/12![United Airlines logo]()
$330
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/310:20 am
RDU
- MYR
1 stop6h 00m
Multiple Airlines
Mon 9/72:31 pm
MYR
- RDU
1 stop18h 48m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$280
This Delta deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/188:50 am
RDU
- HHH
1 stop6h 42m
Delta
Mon 6/2212:13 pm
HHH
- RDU
1 stop6h 41m
Delta
Deal found 6/15![Delta logo]()
$354
This Southwest deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:00 am
RDU
- SAV
1 stop4h 10m
Southwest
Thu 7/167:55 pm
SAV
- RDU
1 stop4h 00m
Southwest
Deal found 6/13![Southwest logo]()
$327
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/49:07 pm
RDU
- CHS
1 stop11h 36m
Breeze Airways
Mon 9/74:57 pm
CHS
- RDU
1 stop21h 49m
Breeze Airways
Deal found 6/12![Breeze Airways logo]()
$298
This United Airlines deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/251:15 pm
RDU
- GSP
1 stop7h 52m
United Airlines
Wed 8/267:47 pm
GSP
- RDU
1 stop4h 12m
United Airlines
Deal found 6/14![United Airlines logo]()
$343
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/101:40 pm
RDU
- MYR
1 stop19h 10m
Multiple Airlines
Tue 11/1710:45 am
MYR
- RDU
1 stop10h 42m
Multiple Airlines
Deal found 6/14![Multiple Airlines logo]()
$285
This American Airlines deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/193:07 pm
RDU
- MYR
1 stop4h 56m
American Airlines
Sat 7/258:44 pm
MYR
- RDU
1 stop3h 14m
American Airlines
Deal found 6/15![American Airlines logo]()
$347
This JetBlue deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/142:00 pm
RDU
- CLT
1 stop7h 09m
JetBlue
Wed 7/153:10 pm
CLT
- RDU
1 stop6h 14m
JetBlue
Deal found 6/14![JetBlue logo]()
$363
This Southwest deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:45 am
RDU
- SAV
2 stops8h 50m
Southwest
Thu 8/1311:25 am
SAV
- RDU
2 stops7h 25m
Southwest
Deal found 6/14![Southwest logo]()
$337
This Breeze Airways deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/2511:16 am
RDU
- CHS
1 stop3h 50m
Breeze Airways
Sun 6/286:45 am
CHS
- RDU
1 stop3h 51m
Breeze Airways
Deal found 6/10![Breeze Airways logo]()
$315
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:25 am
RDU
- HHH
1 stop7h 38m
United Airlines
Wed 8/192:48 pm
HHH
- RDU
1 stop7h 01m
United Airlines
Deal found 6/11![United Airlines logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/710:34 pm
RDU
- MYR
1 stop13h 05m
Multiple Airlines
Fri 7/108:41 pm
MYR
- RDU
1 stop25h 08m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$292
This CheapOair deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1811:00 am
RDU
- CHS
1 stop8h 24m
JetBlue
Sun 7/196:30 pm
CHS
- RDU
1 stop14h 54m
JetBlue
Deal found 6/11![JetBlue logo]()
$367
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/246:35 am
RDU
- GSP
1 stop5h 40m
Southwest
Mon 7/271:55 pm
GSP
- RDU
1 stop3h 35m
Southwest
Deal found 6/11![Southwest logo]()
$347
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/2310:25 am
RDU
- MYR
2 stops7h 20m
Breeze Airways
Sun 7/266:25 pm
MYR
- RDU
1 stop12h 57m
Breeze Airways
Deal found 6/11![Breeze Airways logo]()
$322
Last-minute flights from Durham to South CarolinaDiscover last-minute flight deals from Durham to South Carolina. Data last updated June 15, 2026 and is based on user searches.
Discover last-minute flight deals from Durham to South Carolina. Data last updated June 15, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2710:03 pm
RDU
- CHS
1 stop10h 35m
Multiple Airlines
Tue 6/303:13 pm
CHS
- RDU
1 stop18h 06m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/67:32 pm
RDU
- CHS
1 stop13h 06m
Multiple Airlines
Thu 7/92:53 pm
CHS
- RDU
1 stop18h 07m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/68:29 pm
RDU
- CHS
1 stop12h 09m
Breeze Airways
Wed 7/84:04 pm
CHS
- RDU
1 stop16h 56m
Breeze Airways
Deal found 6/11![Breeze Airways logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/710:22 pm
RDU
- CHS
1 stop10h 46m
Multiple Airlines
Thu 7/92:53 pm
CHS
- RDU
1 stop18h 23m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:14 pm
RDU
- CLT
1 stop22h 58m
Frontier
Wed 7/156:41 pm
CLT
- RDU
1 stop22h 28m
Frontier
Deal found 6/10![Frontier logo]()
$208
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:14 pm
RDU
- CLT
1 stop22h 58m
Multiple Airlines
Wed 7/156:41 pm
CLT
- RDU
2 stops15h 04m
Multiple Airlines
Deal found 6/10![Multiple Airlines logo]()
$214
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/89:48 pm
RDU
- CHS
1 stop10h 50m
Breeze Airways
Fri 7/109:44 pm
CHS
- RDU
1 stop11h 14m
Breeze Airways
Deal found 6/11![Breeze Airways logo]()
$233
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/1210:25 am
RDU
- CLT
2 stops10h 42m
Multiple Airlines
Mon 7/206:41 pm
CLT
- RDU
1 stop22h 28m
Multiple Airlines
Deal found 6/10![Multiple Airlines logo]()
$248
This Kiwi.com deal was found by Cheapflights users on 6/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/1312:04 pm
RDU
- CLT
2 stops9h 03m
Frontier
Wed 7/156:41 pm
CLT
- RDU
1 stop22h 28m
Frontier
Deal found 6/14![Frontier logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/188:06 pm
RDU
- CHS
1 stop12h 32m
Multiple Airlines
Wed 7/224:04 pm
CHS
- RDU
1 stop16h 56m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$221
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/218:56 am
RDU
- CLT
1 stop12h 11m
Frontier
Tue 7/286:48 pm
CLT
- RDU
1 stop22h 41m
Frontier
Deal found 6/15![Frontier logo]()
$197
This Kiwi.com deal was found by Cheapflights users on 6/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2111:55 am
RDU
- CLT
2 stops9h 12m
Multiple Airlines
Tue 7/286:48 pm
CLT
- RDU
1 stop22h 41m
Multiple Airlines
Deal found 6/15![Multiple Airlines logo]()
$201
One-way flights from Durham to South CarolinaSearch for one-way flight options from Durham to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 15, 2026.
Search for one-way flight options from Durham to South Carolina. Find affordable one-way fares based on user searches. Data last updated June 15, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/118:56 am
RDU
- CLT
1 stop12h 17m
Frontier
Deal found 6/12![Frontier logo]()
$90
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1111:55 am
RDU
- CLT
2 stops9h 18m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$92
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/68:56 am
RDU
- CLT
1 stop12h 17m
Frontier
Deal found 6/11![Frontier logo]()
$102
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/168:56 am
RDU
- CLT
1 stop12h 11m
Frontier
Deal found 6/10![Frontier logo]()
$104
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/910:25 am
RDU
- CLT
2 stops10h 42m
Multiple Airlines
Deal found 6/13![Multiple Airlines logo]()
$105
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:29 pm
RDU
- GSP
1 stop14h 06m
Multiple Airlines
Deal found 6/10![Multiple Airlines logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/610:25 am
RDU
- CLT
2 stops10h 48m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 6/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1010:05 am
RDU
- CLT
1 stop9h 50m
Frontier
Deal found 6/13![Frontier logo]()
$108
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:14 pm
RDU
- CLT
1 stop22h 58m
Frontier
Deal found 6/11![Frontier logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/222:31 pm
RDU
- CHS
1 stop18h 07m
Multiple Airlines
Deal found 6/10![Multiple Airlines logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:14 pm
RDU
- CLT
1 stop22h 58m
Frontier
Deal found 6/11![Frontier logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1010:42 am
RDU
- CLT
2 stops9h 13m
Multiple Airlines
Deal found 6/11![Multiple Airlines logo]()
$113
Find flight deals from Durham to South Carolina
Keep the following information in mind while searching for Durham to South Carolina flight deals. Data was last updated June 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $197 (Kiwi.com) |
One-way from | $90 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Durham to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 15, 2026.
Use the filters below to find and compare flights from Durham to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RaleighCharleston
RDU - CHS
RDUCHS
Raleigh-Durham
Thu 7/9
11:16 am-3:06 pm
1 stop3h 50m
Charleston
Thu 7/16
6:45 am-10:36 am
1 stop3h 51m
$221
RaleighCharleston
RDU - CHS
RDUCHS
Raleigh-Durham
Sat 7/18
8:06 pm-8:38 am
1 stop12h 32m
Charleston
Wed 7/22
4:04 pm-9:00 am
1 stop16h 56m
$221
RaleighCharlotte
RDU - CLT
RDUCLT
Raleigh-Durham
Tue 8/18
6:45 am-12:45 pm
1 stop6h 00m
Charlotte Douglas
Tue 8/25
8:30 am-2:55 pm
1 stop6h 25m
$228
RaleighSavannah
RDU - SAV
RDUSAV
Raleigh-Durham
Mon 8/10
6:15 am-11:24 pm
2 stops17h 09m
Savannah/Hilton Head
Thu 8/13
10:05 am-5:15 pm
1 stop7h 10m
$262
RaleighSavannah
RDU - SAV
RDUSAV
Raleigh-Durham
Sat 7/18
11:00 am-6:22 pm
1 stop7h 22m
Savannah/Hilton Head
Tue 7/21
10:56 am-4:47 pm
1 stop5h 51m
$263
RaleighSavannah
RDU - SAV
RDUSAV
Raleigh-Durham
Tue 8/25
10:59 am-6:20 pm
1 stop7h 21m
Savannah/Hilton Head
Wed 8/26
10:55 am-4:46 pm
1 stop5h 51m
$263
RaleighMyrtle Beach
RDU - MYR
RDUMYR
Raleigh-Durham
Thu 8/13
10:34 pm-2:06 pm
1 stop15h 32m
Myrtle Beach Intl
Mon 8/17
3:31 pm-11:15 am
2 stops19h 44m
$266
RaleighMyrtle Beach
RDU - MYR
RDUMYR
Raleigh-Durham
Tue 11/10
1:27 pm-9:08 am
2 stops19h 41m
Myrtle Beach Intl
Tue 11/17
10:45 am-9:27 pm
1 stop10h 42m
$276
RaleighMyrtle Beach
RDU - MYR
RDUMYR
Raleigh-Durham
Thu 9/3
10:20 am-4:20 pm
1 stop6h 00m
Myrtle Beach Intl
Mon 9/7
2:31 pm-9:19 am
1 stop18h 48m
$280
RaleighMyrtle Beach
RDU - MYR
RDUMYR
Raleigh-Durham
Tue 11/10
1:40 pm-8:50 am
1 stop19h 10m
Myrtle Beach Intl
Tue 11/17
10:45 am-9:27 pm
1 stop10h 42m
$285
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Durham to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Durham with our price prediction graph.
RDU-CLT
RDU-CHS
RDU-GSP
RDU-SAV
RDU-HHH
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Durham to South Carolina
DU8-USSC
RDU-CLT
RDU-CHS
RDU-GSP
RDU-SAV
How much does it cost to fly round-trip from Durham to South Carolina?
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated June 15, 2026.
Get a feel of what it's like to fly with Breeze Airways,Delta, andAmerican Airlines from Durham to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.8
Overall
8.2
Comfort
8.2
Entertainment
6.6
Food
6.7
Boarding
8.3
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Crew
8.8
Overall
8.2
Comfort
8.2
Entertainment
6.6
Food
6.7
Boarding
8.3
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Crew
8.8
Overall
8.2
Comfort
8.2
Entertainment
6.6
Food
6.7
Boarding
8.3
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Crew
8.8
Overall
8.2
Comfort
8.2
Entertainment
6.6
Food
6.7
Boarding
8.3
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Related info for your journey
Find useful and relevant information for your journey from Durham to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Durham to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Durham to South Carolina by cabin class
Find flights from Durham to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Durham and South Carolina flights
Browse other Durham and South Carolina flight options. Last updated on June 15, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Durham after your stay in South Carolina
Durham to South Carolina flights
Consider these flights traveling from Durham to South Carolina.
Top 3 airlines flying from Durham to South Carolina
Discover the top 3 airlines that operate flights from Durham to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$54 | Average$258 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$248 | Average$441 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$283 | Average$412 | FlexibilityNo cancel fee | On-timeN/A |