$92+ Cheap flights from Durham, NC to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/26. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — CHS
Aug 28 — Sep 41
Round-trip
1 adult, Economy
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Find cheap flights from Durham to South Carolina with Cheapflights
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Cheapest flights from Durham to South CarolinaExplore the most affordable flight options available from Durham to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2026.
Explore the most affordable flight options available from Durham to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/88:16 pm
RDU
- CHS
1 stop12h 22m
Multiple Airlines
Tue 9/159:18 am
CHS
- RDU
1 stop7h 13m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/228:16 pm
RDU
- CHS
1 stop12h 22m
Multiple Airlines
Wed 8/264:04 pm
CHS
- RDU
1 stop16h 14m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/99:35 pm
RDU
- GSP
1 stop22h 14m
Multiple Airlines
Wed 9/168:24 pm
GSP
- RDU
1 stop19h 30m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$202
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/108:29 pm
RDU
- CHS
1 stop12h 09m
Breeze Airways
Thu 8/136:45 am
CHS
- RDU
1 stop3h 51m
Breeze Airways
Deal found 7/27![Breeze Airways logo]()
$205
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:16 pm
RDU
- CHS
1 stop12h 52m
Multiple Airlines
Tue 9/13:13 pm
CHS
- RDU
1 stop18h 39m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$206
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/99:35 pm
RDU
- CHS
1 stop11h 03m
Multiple Airlines
Wed 9/166:00 am
CHS
- RDU
1 stop26h 59m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$207
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/219:27 pm
RDU
- MYR
1 stop14h 12m
Multiple Airlines
Thu 8/275:15 pm
MYR
- RDU
1 stop14h 07m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$208
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/108:24 pm
RDU
- CHS
1 stop24h 34m
Breeze Airways
Thu 9/173:47 pm
CHS
- RDU
1 stop28h 30m
Breeze Airways
Deal found 7/28![Breeze Airways logo]()
$208
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/268:16 pm
RDU
- CHS
1 stop12h 22m
Multiple Airlines
Wed 9/28:56 pm
CHS
- RDU
2 stops27h 03m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/113:17 pm
RDU
- CHS
1 stop17h 21m
Breeze Airways
Fri 9/189:36 pm
CHS
- RDU
1 stop10h 32m
Breeze Airways
Deal found 7/28![Breeze Airways logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/219:13 am
RDU
- GSP
1 stop6h 47m
Multiple Airlines
Mon 8/2412:06 pm
GSP
- RDU
2 stops23h 09m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$214
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:16 pm
RDU
- CLT
1 stop11h 45m
Frontier
Thu 8/2011:50 am
CLT
- RDU
2 stops12h 09m
Frontier
Deal found 7/28![Frontier logo]()
$215
Best flights from Durham to South CarolinaDiscover carefully curated flight deals from Durham to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 29, 2026.
Discover carefully curated flight deals from Durham to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/88:16 pm
RDU
- CHS
1 stop12h 22m
Multiple Airlines
Tue 9/159:18 am
CHS
- RDU
1 stop7h 13m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$201
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:16 pm
RDU
- CLT
1 stop11h 45m
Frontier
Thu 8/2011:50 am
CLT
- RDU
2 stops12h 09m
Frontier
Deal found 7/28![Frontier logo]()
$215
This JetBlue deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/111:00 pm
RDU
- CHS
1 stop5h 30m
JetBlue
Fri 9/1812:44 pm
CHS
- RDU
1 stop8h 23m
JetBlue
Deal found 7/28![JetBlue logo]()
$255
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/183:35 pm
RDU
- SAV
1 stop3h 19m
Delta
Wed 8/195:35 am
SAV
- RDU
1 stop3h 27m
Delta
Deal found 7/27![Delta logo]()
$275
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/97:35 pm
RDU
- GSP
1 stop3h 18m
American Airlines
Wed 9/1610:02 am
GSP
- RDU
1 stop4h 44m
American Airlines
Deal found 7/26![American Airlines logo]()
$278
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/54:20 pm
RDU
- SAV
1 stop5h 10m
Southwest
Wed 10/711:40 am
SAV
- RDU
2 stops9h 30m
Southwest
Deal found 7/27![Southwest logo]()
$280
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:44 pm
RDU
- MYR
1 stop19h 00m
Breeze Airways
Fri 11/139:25 am
MYR
- RDU
1 stop12h 02m
Breeze Airways
Deal found 7/24![Breeze Airways logo]()
$287
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:25 am
RDU
- HHH
1 stop6h 34m
United Airlines
Thu 9/172:48 pm
HHH
- RDU
1 stop7h 01m
United Airlines
Deal found 7/27![United Airlines logo]()
$374
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/99:35 pm
RDU
- GSP
1 stop22h 14m
Multiple Airlines
Wed 9/168:24 pm
GSP
- RDU
1 stop19h 30m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$202
This JetBlue deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/121:00 pm
RDU
- CHS
1 stop5h 30m
JetBlue
Wed 9/2311:08 am
CHS
- RDU
1 stop6h 41m
JetBlue
Deal found 7/27![JetBlue logo]()
$255
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/912:05 pm
RDU
- MYR
1 stop20h 47m
Multiple Airlines
Wed 9/165:58 pm
MYR
- RDU
1 stop21h 56m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$237
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2712:51 pm
RDU
- SAV
1 stop4h 41m
Delta
Mon 8/316:37 pm
SAV
- RDU
1 stop6h 05m
Delta
Deal found 7/28![Delta logo]()
$275
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:45 am
RDU
- SAV
1 stop5h 45m
Southwest
Wed 8/196:45 am
SAV
- RDU
2 stops10h 50m
Southwest
Deal found 7/27![Southwest logo]()
$280
This JetBlue deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3110:16 am
RDU
- CHS
1 stop6h 50m
JetBlue
Fri 9/41:00 pm
CHS
- RDU
1 stop9h 59m
JetBlue
Deal found 7/28![JetBlue logo]()
$257
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/710:17 am
RDU
- HHH
1 stop6h 21m
American Airlines
Mon 9/1412:50 pm
HHH
- RDU
1 stop4h 11m
American Airlines
Deal found 7/24![American Airlines logo]()
$288
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/102:31 pm
RDU
- CHS
1 stop18h 07m
Multiple Airlines
Thu 8/136:45 am
CHS
- RDU
1 stop3h 51m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$239
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:00 am
RDU
- SAV
2 stops6h 25m
Southwest
Mon 8/3111:25 am
SAV
- RDU
1 stop4h 45m
Southwest
Deal found 7/26![Southwest logo]()
$280
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1010:30 am
RDU
- HHH
1 stop6h 15m
American Airlines
Sun 9/136:29 pm
HHH
- RDU
1 stop5h 26m
American Airlines
Deal found 7/26![American Airlines logo]()
$289
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/179:27 pm
RDU
- GSP
1 stop17h 39m
Multiple Airlines
Fri 8/218:45 pm
GSP
- RDU
1 stop13h 07m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$240
This Delta deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2211:14 am
RDU
- SAV
1 stop4h 27m
Delta
Fri 12/115:30 am
SAV
- RDU
1 stop3h 23m
Delta
Deal found 7/26![Delta logo]()
$307
This Southwest deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/83:35 pm
RDU
- GSP
1 stop3h 55m
Southwest
Tue 9/157:00 am
GSP
- RDU
2 stops7h 55m
Southwest
Deal found 7/24![Southwest logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/74:02 pm
RDU
- GSP
2 stops23h 04m
Multiple Airlines
Mon 9/148:32 pm
GSP
- RDU
1 stop12h 37m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$241
This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:00 am
RDU
- CLT
1 stop13h 19m
American Airlines
Sun 9/62:30 pm
CLT
- RDU
1 stop7h 38m
American Airlines
Deal found 7/27![American Airlines logo]()
$302
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:15 am
RDU
- GSP
1 stop4h 10m
Delta
Fri 9/186:25 pm
GSP
- RDU
1 stop4h 55m
Delta
Deal found 7/28![Delta logo]()
$307
This JetBlue deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1810:58 am
RDU
- SAV
1 stop7h 26m
JetBlue
Thu 8/2010:55 am
SAV
- RDU
1 stop5h 52m
JetBlue
Deal found 7/28![JetBlue logo]()
$311
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/286:55 am
RDU
- HHH
1 stop6h 10m
United Airlines
Tue 9/12:58 pm
HHH
- RDU
1 stop6h 51m
United Airlines
Deal found 7/28![United Airlines logo]()
$379
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/910:15 am
RDU
- GSP
2 stops6h 30m
Southwest
Wed 9/167:00 am
GSP
- RDU
2 stops7h 55m
Southwest
Deal found 7/26![Southwest logo]()
$289
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/610:20 am
RDU
- MYR
1 stop6h 00m
Multiple Airlines
Sun 9/132:46 pm
MYR
- RDU
1 stop18h 14m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$242
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/115:15 am
RDU
- SAV
1 stop3h 59m
Delta
Sun 9/135:30 am
SAV
- RDU
1 stop4h 32m
Delta
Deal found 7/28![Delta logo]()
$331
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/610:20 am
RDU
- SAV
1 stop11h 01m
Multiple Airlines
Sun 9/139:15 am
SAV
- RDU
2 stops15h 14m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$250
Last-minute flights from Durham to South CarolinaDiscover last-minute flight deals from Durham to South Carolina. Data last updated July 29, 2026 and is based on user searches.
Discover last-minute flight deals from Durham to South Carolina. Data last updated July 29, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/108:29 pm
RDU
- CHS
1 stop12h 09m
Breeze Airways
Thu 8/136:45 am
CHS
- RDU
1 stop3h 51m
Breeze Airways
Deal found 7/27![Breeze Airways logo]()
$205
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:16 pm
RDU
- CLT
1 stop11h 45m
Frontier
Thu 8/2011:50 am
CLT
- RDU
2 stops12h 09m
Frontier
Deal found 7/28![Frontier logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/219:27 pm
RDU
- MYR
1 stop14h 12m
Multiple Airlines
Thu 8/275:15 pm
MYR
- RDU
1 stop14h 07m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$208
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/219:13 am
RDU
- GSP
1 stop6h 47m
Multiple Airlines
Mon 8/2412:06 pm
GSP
- RDU
2 stops23h 09m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$214
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/228:16 pm
RDU
- CHS
1 stop12h 22m
Multiple Airlines
Wed 8/264:04 pm
CHS
- RDU
1 stop16h 14m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/229:48 pm
RDU
- CLT
1 stop10h 13m
Multiple Airlines
Sat 8/298:56 am
CLT
- RDU
1 stop8h 14m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$217
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/236:35 pm
RDU
- CHS
2 stops23h 36m
Breeze Airways
Sun 8/306:45 am
CHS
- RDU
1 stop3h 51m
Breeze Airways
Deal found 7/24![Breeze Airways logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/249:50 am
RDU
- GSP
1 stop10h 15m
Multiple Airlines
Mon 8/315:34 pm
GSP
- RDU
2 stops17h 41m
Multiple Airlines
Deal found 7/25![Multiple Airlines logo]()
$218
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/249:59 pm
RDU
- CLT
1 stop10h 02m
Frontier
Mon 8/3111:50 am
CLT
- RDU
2 stops12h 09m
Frontier
Deal found 7/27![Frontier logo]()
$221
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:16 pm
RDU
- CHS
1 stop12h 52m
Multiple Airlines
Tue 9/13:13 pm
CHS
- RDU
1 stop18h 39m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$206
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/268:16 pm
RDU
- CHS
1 stop12h 22m
Multiple Airlines
Wed 9/28:56 pm
CHS
- RDU
2 stops27h 03m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$210
This Priceline deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2810:53 am
RDU
- CHS
1 stop6h 13m
Multiple Airlines
Sun 8/306:45 am
CHS
- RDU
1 stop3h 51m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$223
One-way flights from Durham to South CarolinaSearch for one-way flight options from Durham to South Carolina. Find affordable one-way fares based on user searches. Data last updated July 29, 2026.
Search for one-way flight options from Durham to South Carolina. Find affordable one-way fares based on user searches. Data last updated July 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/265:58 pm
RDU
- CHS
1 stop14h 40m
Multiple Airlines
Deal found 7/28![Multiple Airlines logo]()
$92
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/289:59 pm
RDU
- CLT
1 stop10h 02m
Frontier
Deal found 7/27![Frontier logo]()
$101
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/195:58 pm
RDU
- CLT
1 stop14h 03m
Frontier
Deal found 7/26![Frontier logo]()
$103
This Kiwi.com deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2712:53 pm
RDU
- CLT
1 stop19h 08m
Frontier
Deal found 7/28![Frontier logo]()
$104
This Kiwi.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/249:59 pm
RDU
- CLT
1 stop10h 02m
Frontier
Deal found 7/25![Frontier logo]()
$105
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/265:58 pm
RDU
- CLT
1 stop14h 03m
Frontier
Deal found 7/26![Frontier logo]()
$106
This Kiwi.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/184:49 pm
RDU
- CHS
1 stop20h 35m
Multiple Airlines
Deal found 7/25![Multiple Airlines logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/239:35 pm
RDU
- CLT
1 stop11h 00m
Frontier
Deal found 7/25![Frontier logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/249:35 pm
RDU
- CHS
1 stop9h 50m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$108
This Kiwi.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/279:35 pm
RDU
- CLT
1 stop11h 00m
Frontier
Deal found 7/25![Frontier logo]()
$108
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/253:47 pm
RDU
- SAV
1 stop26h 08m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/29:35 pm
RDU
- CLT
1 stop11h 00m
Frontier
Deal found 7/26![Frontier logo]()
$109
Find flight deals from Durham to South Carolina
Keep the following information in mind while searching for Durham to South Carolina flight deals. Data was last updated July 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $180 (Kiwi.com) |
One-way from | $92 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Durham to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2026.
Use the filters below to find and compare flights from Durham to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RaleighCharleston
RDU - CHS
RDUCHS
Raleigh-Durham
Tue 9/8
8:16 pm-8:38 am
1 stop12h 22m
Charleston
Tue 9/15
9:18 am-4:31 pm
1 stop7h 13m
$201
RaleighGreenville
RDU - GSP
RDUGSP
Raleigh-Durham
Wed 9/9
9:35 pm-7:49 pm
1 stop22h 14m
Greenville
Wed 9/16
8:24 pm-3:54 pm
1 stop19h 30m
$202
RaleighCharlotte
RDU - CLT
RDUCLT
Raleigh-Durham
Tue 8/18
8:16 pm-8:01 am
1 stop11h 45m
Charlotte Douglas
Thu 8/20
11:50 am-11:59 pm
2 stops12h 09m
$215
RaleighMyrtle Beach
RDU - MYR
RDUMYR
Raleigh-Durham
Wed 9/9
12:05 pm-8:52 am
1 stop20h 47m
Myrtle Beach Intl
Wed 9/16
5:58 pm-3:54 pm
1 stop21h 56m
$237
RaleighCharleston
RDU - CHS
RDUCHS
Raleigh-Durham
Mon 8/10
2:31 pm-8:38 am
1 stop18h 07m
Charleston
Thu 8/13
6:45 am-10:36 am
1 stop3h 51m
$239
RaleighGreenville
RDU - GSP
RDUGSP
Raleigh-Durham
Mon 8/17
9:27 pm-3:06 pm
1 stop17h 39m
Greenville
Fri 8/21
8:45 pm-9:52 am
1 stop13h 07m
$240
RaleighGreenville
RDU - GSP
RDUGSP
Raleigh-Durham
Mon 9/7
4:02 pm-3:06 pm
2 stops23h 04m
Greenville
Mon 9/14
8:32 pm-9:09 am
1 stop12h 37m
$241
RaleighMyrtle Beach
RDU - MYR
RDUMYR
Raleigh-Durham
Sun 9/6
10:20 am-4:20 pm
1 stop6h 00m
Myrtle Beach Intl
Sun 9/13
2:46 pm-9:00 am
1 stop18h 14m
$242
RaleighSavannah
RDU - SAV
RDUSAV
Raleigh-Durham
Sun 9/6
10:20 am-9:21 pm
1 stop11h 01m
Savannah/Hilton Head
Sun 9/13
9:15 am-12:29 am
2 stops15h 14m
$250
RaleighCharleston
RDU - CHS
RDUCHS
Raleigh-Durham
Fri 9/11
1:00 pm-6:30 pm
1 stop5h 30m
Charleston
Fri 9/18
12:44 pm-9:07 pm
1 stop8h 23m
$255
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Durham to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Durham with our price prediction graph.
RDU-CHS
RDU-MYR
RDU-GSP
RDU-CLT
RDU-SAV
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Durham to South Carolina
DU8-USSC
RDU-CHS
RDU-MYR
RDU-GSP
RDU-CLT
How much does it cost to fly round-trip from Durham to South Carolina?
Airfare is below average for this route at the moment.
Durham to South Carolina flights typically cost between $287 and $588 in September.The cheapest round-trip price found within the last 5 days was $180 on Multiple Airlines (Sep 8-Sep 15).
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated July 29, 2026.
Get a feel of what it's like to fly with American Airlines from Durham to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.4
Overall
7.1
Boarding
7.5
Comfort
7.2
Crew
7.9
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreSusie,Jan 2026
CLT - TPA
Food
6.4
Overall
7.1
Boarding
7.5
Comfort
7.2
Crew
7.9
Entertainment
6.8
Reviews
1 / 20
2.0
MediocreSusie,Jan 2026
CLT - TPA
Related info for your journey
Find useful and relevant information for your journey from Durham to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Durham to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Durham to South Carolina by cabin class
Find flights from Durham to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Durham and South Carolina flights
Browse other Durham and South Carolina flight options. Last updated on July 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Durham after your stay in South Carolina
Durham to South Carolina flights
Consider these flights traveling from Durham to South Carolina.
Top 2 airlines flying from Durham to South Carolina
Discover the top 2 airlines that operate flights from Durham to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$316 | Average$358 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$326 | Average$448 | FlexibilityNo cancel fee | On-time71% |