$91+ Cheap flights from Durham, NC to South Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/28. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — CHS
Oct 13 — Oct 201
Round-trip
1 adult, Economy
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Find cheap flights from Durham to South Carolina with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Durham to South CarolinaExplore the most affordable flight options available from Durham to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 13, 2026.
Explore the most affordable flight options available from Durham to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:26 pm -
1 stop15h 12m
Thu 10/296:45 am -
1 stop3h 49m
Deal found 9/11![Multiple Airlines logo]()
$181
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2911:14 am -
1 stop3h 51m
Sun 11/16:45 am -
1 stop3h 49m
Deal found 9/11![Breeze Airways logo]()
$190
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/139:53 pm -
1 stop12h 47m
Mon 11/168:54 pm -
1 stop14h 08m
Deal found 9/12![Frontier logo]()
$195
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/251:16 pm -
2 stops47h 15m
Sun 11/16:45 am -
1 stop3h 49m
Deal found 9/10![Multiple Airlines logo]()
$208
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:30 am -
2 stops10h 35m
Thu 11/56:05 am -
1 stop12h 05m
Deal found 9/11![Multiple Airlines logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:05 am -
1 stop7h 33m
Wed 10/213:42 pm -
1 stop17h 38m
Deal found 9/12![Multiple Airlines logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/169:30 pm -
1 stop10h 27m
Mon 10/1911:50 am -
2 stops21h 27m
Deal found 9/10![Frontier logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:30 pm -
1 stop11h 08m
Sun 10/256:45 am -
1 stop3h 49m
Deal found 9/9![Multiple Airlines logo]()
$218
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/39:35 pm -
1 stop11h 03m
Mon 10/53:27 pm -
1 stop18h 33m
Deal found 9/11![Multiple Airlines logo]()
$219
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:05 am -
1 stop14h 39m
Sat 12/510:00 am -
1 stop14h 17m
Deal found 9/12![Frontier logo]()
$222
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/49:35 pm -
1 stop11h 13m
Tue 10/69:18 am -
1 stop7h 13m
Deal found 9/10![Multiple Airlines logo]()
$229
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/259:27 pm -
1 stop11h 10m
Fri 10/306:05 am -
1 stop27h 00m
Deal found 9/11![Multiple Airlines logo]()
$231
Best flights from Durham to South CarolinaDiscover carefully curated flight deals from Durham to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 13, 2026.
Discover carefully curated flight deals from Durham to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:30 pm -
1 stop11h 08m
Sun 10/256:45 am -
1 stop3h 49m
Deal found 9/9![Multiple Airlines logo]()
$218
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:05 am -
1 stop14h 39m
Sat 12/510:00 am -
1 stop14h 17m
Deal found 9/12![Frontier logo]()
$222
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:15 am -
2 stops9h 40m
Wed 11/185:30 pm -
1 stop4h 25m
Deal found 9/9![Southwest logo]()
$300
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/91:39 pm -
1 stop7h 20m
Tue 1/129:15 am -
1 stop8h 47m
Deal found 9/8![American Airlines logo]()
$305
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:59 pm -
1 stop3h 58m
Fri 10/306:31 pm -
1 stop5h 57m
Deal found 9/9![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:20 pm -
1 stop4h 53m
Sat 10/37:35 pm -
1 stop4h 24m
Deal found 9/8![United Airlines logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:43 pm -
2 stops13h 30m
Sun 10/46:25 pm -
1 stop14h 34m
Deal found 9/8![Breeze Airways logo]()
$401
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/249:35 pm -
1 stop9h 50m
Mon 9/283:27 pm -
1 stop17h 42m
Deal found 9/9![Multiple Airlines logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/910:05 am -
1 stop23h 08m
Fri 10/236:12 pm -
2 stops19h 47m
Deal found 9/10![Multiple Airlines logo]()
$241
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/249:35 pm -
1 stop11h 00m
Mon 9/289:40 pm -
1 stop11h 29m
Deal found 9/9![Frontier logo]()
$306
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/61:40 pm -
2 stops7h 25m
Tue 10/137:00 am -
2 stops10h 00m
Deal found 9/8![Southwest logo]()
$330
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:48 pm -
1 stop25h 56m
Tue 10/1311:28 am -
1 stop21h 31m
Deal found 9/8![Multiple Airlines logo]()
$274
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/115:02 am -
1 stop5h 09m
Thu 10/158:34 am -
1 stop5h 25m
Deal found 9/8![American Airlines logo]()
$336
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/268:44 am -
1 stop4h 31m
Sat 11/285:40 am -
1 stop3h 12m
Deal found 9/10![Delta logo]()
$338
This Frontier deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:30 pm -
1 stop10h 27m
Sat 10/249:42 pm -
1 stop11h 38m
Deal found 9/10![Frontier logo]()
$313
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:05 am -
1 stop5h 30m
Sat 10/32:51 pm -
1 stop6h 55m
Deal found 9/9![United Airlines logo]()
$359
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:20 am -
2 stops11h 15m
Sat 10/106:30 am -
2 stops6h 25m
Deal found 9/8![Southwest logo]()
$332
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/254:49 pm -
1 stop26h 55m
Mon 9/288:32 pm -
1 stop12h 37m
Deal found 9/11![Multiple Airlines logo]()
$278
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/295:43 pm -
1 stop6h 13m
Mon 1/46:00 am -
1 stop5h 16m
Deal found 9/8![Delta logo]()
$355
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/97:59 am -
1 stop5h 23m
Sat 12/128:07 am -
1 stop5h 19m
Deal found 9/8![American Airlines logo]()
$357
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/61:00 pm -
1 stop8h 28m
Sat 1/91:50 pm -
2 stops9h 36m
Deal found 9/10![United Airlines logo]()
$370
This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:05 am -
2 stops9h 50m
Thu 12/106:35 am -
1 stop6h 10m
Deal found 9/11![Southwest logo]()
$354
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:03 am -
1 stop5h 18m
Mon 11/96:12 am -
1 stop5h 05m
Deal found 9/8![American Airlines logo]()
$357
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:59 pm -
1 stop3h 58m
Mon 10/128:09 pm -
1 stop4h 19m
Deal found 9/8![Delta logo]()
$367
This Frontier deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2912:05 pm -
1 stop4h 37m
Sat 10/39:32 am -
2 stops14h 57m
Deal found 9/9![Frontier logo]()
$369
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/277:05 am -
1 stop5h 30m
Sat 10/32:51 pm -
1 stop6h 55m
Deal found 9/11![United Airlines logo]()
$374
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/244:18 pm -
1 stop3h 36m
Mon 11/308:35 pm -
1 stop3h 24m
Deal found 9/8![American Airlines logo]()
$357
This Southwest deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:00 am -
2 stops10h 00m
Wed 10/2810:55 am -
2 stops10h 15m
Deal found 9/11![Southwest logo]()
$359
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/303:19 pm -
1 stop4h 53m
Sun 11/14:02 pm -
1 stop24h 29m
Deal found 9/12![Multiple Airlines logo]()
$327
This CheapOair deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/271:32 pm -
3 stops23h 52m
Thu 10/296:45 am -
1 stop3h 49m
Deal found 9/11![Breeze Airways logo]()
$484
Last-minute flights from Durham to South CarolinaDiscover last-minute flight deals from Durham to South Carolina. Data last updated September 13, 2026 and is based on user searches.
Discover last-minute flight deals from Durham to South Carolina. Data last updated September 13, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/39:35 pm -
1 stop11h 03m
Mon 10/53:27 pm -
1 stop18h 33m
Deal found 9/11![Multiple Airlines logo]()
$219
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/31:14 pm -
1 stop25h 04m
Mon 10/58:32 pm -
1 stop12h 37m
Deal found 9/13![Multiple Airlines logo]()
$241
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/49:35 pm -
1 stop11h 13m
Tue 10/69:18 am -
1 stop7h 13m
Deal found 9/10![Multiple Airlines logo]()
$229
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/99:30 pm -
1 stop10h 27m
Sat 10/109:42 pm -
1 stop11h 38m
Deal found 9/10![Frontier logo]()
$240
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/910:05 am -
1 stop23h 08m
Fri 10/236:12 pm -
2 stops19h 47m
Deal found 9/10![Multiple Airlines logo]()
$241
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/169:30 pm -
1 stop10h 27m
Mon 10/1911:50 am -
2 stops21h 27m
Deal found 9/10![Frontier logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:05 am -
1 stop7h 33m
Wed 10/213:42 pm -
1 stop17h 38m
Deal found 9/12![Multiple Airlines logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/239:30 pm -
1 stop11h 08m
Sun 10/256:45 am -
1 stop3h 49m
Deal found 9/9![Multiple Airlines logo]()
$218
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/251:16 pm -
2 stops47h 15m
Sun 11/16:45 am -
1 stop3h 49m
Deal found 9/10![Multiple Airlines logo]()
$208
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/259:27 pm -
1 stop11h 10m
Fri 10/306:05 am -
1 stop27h 00m
Deal found 9/11![Multiple Airlines logo]()
$231
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:26 pm -
1 stop15h 12m
Thu 10/296:45 am -
1 stop3h 49m
Deal found 9/11![Multiple Airlines logo]()
$181
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2911:14 am -
1 stop3h 51m
Sun 11/16:45 am -
1 stop3h 49m
Deal found 9/11![Breeze Airways logo]()
$190
One-way flights from Durham to South CarolinaSearch for one-way flight options from Durham to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 13, 2026.
Search for one-way flight options from Durham to South Carolina. Find affordable one-way fares based on user searches. Data last updated September 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/289:35 pm -
1 stop11h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/12![Multiple Airlines logo]()
$91
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/207:05 am -
1 stop7h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Breeze Airways logo]()
$98
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/610:07 am -
1 stop22h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Frontier logo]()
$98
This Trip.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/89:13 pm -
1 stop23h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Frontier logo]()
$99
This Trip.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:05 am -
1 stop14h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Frontier logo]()
$100
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/49:30 pm -
1 stop11h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$102
This Trip.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/92:45 pm -
1 stop17h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Frontier logo]()
$103
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:30 pm -
2 stops15h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Frontier logo]()
$105
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/249:35 pm -
1 stop9h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Multiple Airlines logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/89:46 pm -
1 stop10h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/11![Multiple Airlines logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/79:47 pm -
1 stop10h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Multiple Airlines logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1811:10 am -
2 stops31h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Multiple Airlines logo]()
$111
Find flight deals from Durham to South Carolina
Keep the following information in mind while searching for Durham to South Carolina flight deals. Data was last updated September 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $181 (Kiwi.com) |
One-way from | $91 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Durham to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 13, 2026.
Use the filters below to find and compare flights from Durham to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RaleighCharleston
RDU Raleigh-Durham - CHS Charleston
RDUCHS
Raleigh-Durham
Tue 10/20
7:05 am-2:38 pm
1 stop7h 33m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$98
RaleighSavannah
RDU Raleigh-Durham - SAV Savannah/Hilton Head
RDUSAV
Raleigh-Durham
Sat 10/3
10:35 am-4:20 pm
1 stop5h 45m
Savannah/Hilton Head
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$116
RaleighGreenville
RDU Raleigh-Durham - GSP Greenville
RDUGSP
Raleigh-Durham
Thu 1/21
7:00 am-7:36 pm
1 stop12h 36m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$116
RaleighGreenville
RDU Raleigh-Durham - GSP Greenville
RDUGSP
Raleigh-Durham
Thu 12/3
6:05 am-7:59 pm
1 stop13h 54m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$120
RaleighCharleston
RDU Raleigh-Durham - CHS Charleston
RDUCHS
Raleigh-Durham
Tue 10/20
4:20 pm-1:24 pm
2 stops21h 04m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$129
RaleighCharlotte
RDU Raleigh-Durham - CLT Charlotte Douglas
RDUCLT
Raleigh-Durham
Thu 11/12
9:30 pm-8:37 am
1 stop11h 07m
Charlotte Douglas
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$134
RaleighMyrtle Beach
RDU Raleigh-Durham - MYR Myrtle Beach Intl
RDUMYR
Raleigh-Durham
Fri 10/9
10:05 am-9:13 am
1 stop23h 08m
Myrtle Beach Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$140
RaleighCharleston
RDU Raleigh-Durham - CHS Charleston
RDUCHS
Raleigh-Durham
Fri 10/2
12:00 pm-6:30 pm
1 stop6h 30m
Charleston
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$144
RaleighGreenville
RDU Raleigh-Durham - GSP Greenville
RDUGSP
Raleigh-Durham
Wed 10/7
1:14 pm-8:45 am
1 stop19h 31m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$145
RaleighGreenville
RDU Raleigh-Durham - GSP Greenville
RDUGSP
Raleigh-Durham
Thu 9/24
2:49 pm-9:50 pm
1 stop7h 01m
Greenville
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$147
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Durham to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Durham with our price prediction graph.
RDU-CHS
RDU-CLT
RDU-GSP
RDU-MYR
RDU-SAV
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Durham to South Carolina
DU8-USSC
RDU-CHS
RDU-CLT
RDU-GSP
RDU-MYR
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated September 13, 2026.
Get a feel of what it's like to fly with Delta and American Airlines from Durham to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Overall
7.8
Boarding
8.1
Crew
8.5
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Comfort
7.8
Overall
7.8
Boarding
8.1
Crew
8.5
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Comfort
7.8
Overall
7.8
Boarding
8.1
Crew
8.5
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Durham to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Durham to South Carolina
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Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Durham to South Carolina by cabin class
Find flights from Durham to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Durham and South Carolina flights
Browse other Durham and South Carolina flight options. Last updated on September 13, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Durham after your stay in South Carolina
Durham to South Carolina flights
Consider these flights traveling from Durham to South Carolina.
Top 2 airlines flying from Durham to South Carolina
Discover the top 2 airlines that operate flights from Durham to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$316 | Average$420 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$326 | Average$474 | FlexibilityNo cancel fee | On-time71% |