$74+ Cheap flights from Durham, NC to South Carolina
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/26. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — CHS
maj 29 — cze 51
Round-trip
1 adult, Economy
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Cheapest flights from Durham to South CarolinaExplore the most affordable flight options available from Durham to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on Kwiecień 29, 2026.
Explore the most affordable flight options available from Durham to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on Kwiecień 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wt. 5/198:01 pm
RDU
- CLT
1 stop20h 42m
Frontier
czw. 5/214:45 pm
CLT
- RDU
1 stop14h 39m
Frontier
Deal found 4/24![Frontier logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wt. 5/269:46 am
RDU
- CLT
1 stop28h 25m
Multiple Airlines
wt. 6/27:30 am
CLT
- RDU
1 stop6h 52m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
śr. 5/277:52 pm
RDU
- CLT
1 stop16h 20m
Frontier
śr. 6/35:50 pm
CLT
- RDU
1 stop20h 32m
Frontier
Deal found 4/27![Frontier logo]()
$153
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pon. 5/1811:47 am
RDU
- CLT
1 stop8h 15m
Multiple Airlines
wt. 5/197:57 pm
CLT
- RDU
1 stop13h 24m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ndz. 5/2410:15 pm
RDU
- CLT
1 stop13h 50m
Multiple Airlines
ndz. 5/3112:48 pm
CLT
- RDU
1 stop18h 36m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pon. 5/118:52 pm
RDU
- CLT
1 stop22h 21m
Frontier
pt. 5/157:58 pm
CLT
- RDU
1 stop13h 23m
Frontier
Deal found 4/27![Frontier logo]()
$158
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ndz. 5/319:46 am
RDU
- CLT
1 stop25h 48m
Multiple Airlines
wt. 6/27:30 am
CLT
- RDU
1 stop6h 52m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
czw. 5/710:11 am
RDU
- CLT
1 stop25h 54m
Frontier
czw. 5/141:12 pm
CLT
- RDU
1 stop20h 09m
Frontier
Deal found 4/27![Frontier logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
czw. 5/2111:47 am
RDU
- CLT
1 stop8h 15m
Multiple Airlines
sob. 5/237:58 pm
CLT
- RDU
1 stop13h 23m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pon. 5/46:12 pm
RDU
- CLT
1 stop17h 53m
Multiple Airlines
czw. 5/1412:48 pm
CLT
- RDU
1 stop18h 36m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$170
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
śr. 5/2712:33 pm
RDU
- CLT
2 stops23h 01m
Multiple Airlines
śr. 6/35:50 pm
CLT
- RDU
1 stop20h 32m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$174
This Mytrip deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pt. 5/1511:47 am
RDU
- MYR
1 stop8h 49m
Spirit Airlines
ndz. 5/176:00 am
MYR
- RDU
1 stop4h 52m
Spirit Airlines
Deal found 4/25![Spirit Airlines logo]()
$197
Best flights from Durham to South CarolinaDiscover carefully curated flight deals from Durham to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated Kwiecień 29, 2026.
Discover carefully curated flight deals from Durham to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated Kwiecień 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pt. 5/158:52 pm
RDU
- CLT
1 stop15h 13m
Multiple Airlines
wt. 5/197:57 pm
CLT
- RDU
1 stop13h 24m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$175
This JetBlue deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wt. 8/1810:59 am
RDU
- SAV
1 stop7h 21m
JetBlue
śr. 8/1910:55 am
SAV
- RDU
1 stop5h 51m
JetBlue
Deal found 4/28![JetBlue logo]()
$253
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
śr. 5/2710:32 am
RDU
- GSP
1 stop3h 48m
United Airlines
śr. 6/310:30 am
GSP
- RDU
1 stop3h 38m
United Airlines
Deal found 4/28![United Airlines logo]()
$287
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
śr. 5/205:20 am
RDU
- GSP
1 stop3h 44m
Delta
czw. 5/215:40 am
GSP
- RDU
1 stop6h 12m
Delta
Deal found 4/26![Delta logo]()
$299
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
śr. 5/276:50 am
RDU
- GSP
2 stops9h 30m
Southwest
śr. 6/36:45 am
GSP
- RDU
2 stops9h 45m
Southwest
Deal found 4/28![Southwest logo]()
$309
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wt. 5/266:00 am
RDU
- MYR
1 stop11h 39m
American Airlines
wt. 6/212:07 pm
MYR
- RDU
1 stop9h 09m
American Airlines
Deal found 4/29![American Airlines logo]()
$311
This Mytrip deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pt. 5/2211:47 am
RDU
- MYR
1 stop8h 49m
Spirit Airlines
ndz. 5/246:00 am
MYR
- RDU
1 stop4h 52m
Spirit Airlines
Deal found 4/27![Spirit Airlines logo]()
$312
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pt. 6/1210:36 pm
RDU
- MYR
1 stop13h 03m
Multiple Airlines
pt. 6/199:05 pm
MYR
- RDU
1 stop24h 15m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sob. 9/129:48 am
RDU
- MYR
1 stop10h 20m
Multiple Airlines
śr. 9/161:36 pm
MYR
- RDU
2 stops20h 26m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$252
This JetBlue deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wt. 6/99:59 am
RDU
- SAV
1 stop7h 04m
JetBlue
śr. 6/1010:42 am
SAV
- RDU
1 stop8h 02m
JetBlue
Deal found 4/26![JetBlue logo]()
$291
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pon. 5/259:56 am
RDU
- SAV
1 stop3h 14m
Delta
śr. 5/275:30 am
SAV
- RDU
1 stop3h 21m
Delta
Deal found 4/25![Delta logo]()
$303
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pon. 6/110:32 am
RDU
- SAV
1 stop4h 11m
United Airlines
śr. 6/39:50 am
SAV
- RDU
1 stop4h 18m
United Airlines
Deal found 4/25![United Airlines logo]()
$303
This Delta deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wt. 5/268:30 am
RDU
- SAV
1 stop6h 16m
Delta
czw. 5/286:36 am
SAV
- RDU
1 stop3h 51m
Delta
Deal found 4/27![Delta logo]()
$303
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sob. 5/306:00 am
RDU
- GSP
2 stops10h 35m
Southwest
ndz. 5/317:05 pm
GSP
- RDU
1 stop3h 50m
Southwest
Deal found 4/28![Southwest logo]()
$334
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ndz. 7/194:15 pm
RDU
- MYR
1 stop5h 29m
American Airlines
sob. 7/258:44 pm
MYR
- RDU
1 stop3h 15m
American Airlines
Deal found 4/24![American Airlines logo]()
$347
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wt. 9/1510:42 am
RDU
- SAV
1 stop4h 05m
United Airlines
pt. 9/187:15 pm
SAV
- RDU
1 stop4h 32m
United Airlines
Deal found 4/28![United Airlines logo]()
$331
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ndz. 5/2411:47 am
RDU
- GSP
1 stop27h 57m
Multiple Airlines
pt. 5/295:05 pm
GSP
- RDU
2 stops14h 59m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$302
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pon. 5/256:28 am
RDU
- SAV
1 stop5h 01m
Delta
wt. 5/266:53 pm
SAV
- RDU
1 stop5h 23m
Delta
Deal found 4/25![Delta logo]()
$303
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
śr. 5/206:50 am
RDU
- GSP
2 stops9h 30m
Southwest
czw. 5/211:50 pm
GSP
- RDU
1 stop4h 40m
Southwest
Deal found 4/26![Southwest logo]()
$339
This Southwest deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
śr. 7/1511:15 am
RDU
- MYR
2 stops9h 15m
Southwest
pon. 7/202:00 pm
MYR
- RDU
2 stops8h 20m
Southwest
Deal found 4/27![Southwest logo]()
$357
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ndz. 5/248:30 am
RDU
- SAV
1 stop6h 16m
Delta
śr. 5/278:12 am
SAV
- RDU
1 stop3h 40m
Delta
Deal found 4/25![Delta logo]()
$325
This American Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pt. 6/196:40 am
RDU
- CHS
1 stop3h 27m
American Airlines
ndz. 6/215:00 am
CHS
- RDU
1 stop3h 07m
American Airlines
Deal found 4/24![American Airlines logo]()
$395
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sob. 5/236:15 am
RDU
- GSP
1 stop3h 40m
United Airlines
sob. 5/306:00 am
GSP
- RDU
1 stop8h 01m
United Airlines
Deal found 4/25![United Airlines logo]()
$381
This CheapOair deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
śr. 7/1510:00 am
RDU
- CHS
1 stop6h 31m
Multiple Airlines
ndz. 7/196:45 am
CHS
- RDU
1 stop3h 51m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$347
This Mytrip deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pt. 5/2911:47 am
RDU
- MYR
2 stops21h 59m
Spirit Airlines
pt. 6/56:00 am
MYR
- RDU
3 stops11h 40m
Spirit Airlines
Deal found 4/29![Spirit Airlines logo]()
$475
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sob. 5/234:37 pm
RDU
- SAV
1 stop4h 23m
Delta
ndz. 5/246:36 am
SAV
- RDU
1 stop3h 51m
Delta
Deal found 4/25![Delta logo]()
$333
This Southwest deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pon. 5/254:50 pm
RDU
- CLT
1 stop4h 50m
Southwest
pon. 6/16:15 am
CLT
- RDU
1 stop5h 55m
Southwest
Deal found 4/26![Southwest logo]()
$367
This American Airlines deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pt. 5/296:43 am
RDU
- CAE
1 stop4h 01m
American Airlines
ndz. 5/315:00 am
CAE
- RDU
1 stop3h 07m
American Airlines
Deal found 4/27![American Airlines logo]()
$422
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pon. 5/259:56 am
RDU
- SAV
1 stop6h 12m
Delta
pt. 5/295:30 am
SAV
- RDU
1 stop4h 57m
Delta
Deal found 4/25![Delta logo]()
$333
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wt. 5/263:50 pm
RDU
- CLT
1 stop4h 55m
Southwest
wt. 6/26:40 am
CLT
- RDU
1 stop6h 05m
Southwest
Deal found 4/28![Southwest logo]()
$367
Last-minute flights from Durham to South CarolinaDiscover last-minute flight deals from Durham to South Carolina. Data last updated Kwiecień 29, 2026 and is based on user searches.
Discover last-minute flight deals from Durham to South Carolina. Data last updated Kwiecień 29, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pon. 5/46:12 pm
RDU
- CLT
1 stop17h 53m
Multiple Airlines
czw. 5/1412:48 pm
CLT
- RDU
1 stop18h 36m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$170
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
czw. 5/710:11 am
RDU
- CLT
1 stop25h 54m
Frontier
czw. 5/141:12 pm
CLT
- RDU
1 stop20h 09m
Frontier
Deal found 4/27![Frontier logo]()
$164
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pon. 5/118:52 pm
RDU
- CLT
1 stop22h 21m
Frontier
pt. 5/157:58 pm
CLT
- RDU
1 stop13h 23m
Frontier
Deal found 4/27![Frontier logo]()
$158
This Mytrip deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pt. 5/1511:47 am
RDU
- MYR
1 stop8h 49m
Spirit Airlines
ndz. 5/176:00 am
MYR
- RDU
1 stop4h 52m
Spirit Airlines
Deal found 4/25![Spirit Airlines logo]()
$197
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pon. 5/1811:47 am
RDU
- CLT
1 stop8h 15m
Multiple Airlines
wt. 5/197:57 pm
CLT
- RDU
1 stop13h 24m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wt. 5/198:01 pm
RDU
- CLT
1 stop20h 42m
Frontier
czw. 5/214:45 pm
CLT
- RDU
1 stop14h 39m
Frontier
Deal found 4/24![Frontier logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
czw. 5/2111:47 am
RDU
- CLT
1 stop8h 15m
Multiple Airlines
sob. 5/237:58 pm
CLT
- RDU
1 stop13h 23m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$168
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ndz. 5/2410:15 pm
RDU
- CLT
1 stop13h 50m
Multiple Airlines
ndz. 5/3112:48 pm
CLT
- RDU
1 stop18h 36m
Multiple Airlines
Deal found 4/25![Multiple Airlines logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wt. 5/269:46 am
RDU
- CLT
1 stop28h 25m
Multiple Airlines
wt. 6/27:30 am
CLT
- RDU
1 stop6h 52m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
śr. 5/277:52 pm
RDU
- CLT
1 stop16h 20m
Frontier
śr. 6/35:50 pm
CLT
- RDU
1 stop20h 32m
Frontier
Deal found 4/27![Frontier logo]()
$153
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
śr. 5/2712:33 pm
RDU
- CLT
2 stops23h 01m
Multiple Airlines
śr. 6/35:50 pm
CLT
- RDU
1 stop20h 32m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$174
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ndz. 5/319:46 am
RDU
- CLT
1 stop25h 48m
Multiple Airlines
wt. 6/27:30 am
CLT
- RDU
1 stop6h 52m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$162
One-way flights from Durham to South CarolinaSearch for one-way flight options from Durham to South Carolina. Find affordable one-way fares based on user searches. Data last updated Kwiecień 29, 2026.
Search for one-way flight options from Durham to South Carolina. Find affordable one-way fares based on user searches. Data last updated Kwiecień 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wt. 5/269:46 am
RDU
- CLT
1 stop26h 19m
Frontier
Deal found 4/26![Frontier logo]()
$74
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wt. 5/269:46 am
RDU
- CLT
1 stop28h 25m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$78
This Mytrip deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pon. 5/1811:47 am
RDU
- CLT
1 stop8h 15m
Spirit Airlines
Deal found 4/29![Spirit Airlines logo]()
$79
This Mytrip deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
czw. 5/1411:47 am
RDU
- CLT
1 stop11h 53m
Spirit Airlines
Deal found 4/29![Spirit Airlines logo]()
$80
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pon. 5/112:32 pm
RDU
- CLT
1 stop28h 41m
Frontier
Deal found 4/27![Frontier logo]()
$82
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pon. 5/257:52 pm
RDU
- CLT
1 stop16h 13m
Frontier
Deal found 4/24![Frontier logo]()
$83
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
śr. 5/277:52 pm
RDU
- CLT
1 stop23h 00m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$87
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sob. 5/237:52 pm
RDU
- CHS
1 stop12h 46m
Multiple Airlines
Deal found 4/24![Multiple Airlines logo]()
$88
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sob. 5/237:52 pm
RDU
- CLT
1 stop16h 20m
Frontier
Deal found 4/28![Frontier logo]()
$89
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pon. 5/46:12 pm
RDU
- CLT
1 stop17h 53m
Frontier
Deal found 4/24![Frontier logo]()
$91
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pon. 6/225:07 pm
RDU
- CLT
1 stop18h 27m
Frontier
Deal found 4/26![Frontier logo]()
$93
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pt. 5/88:52 pm
RDU
- CLT
1 stop15h 13m
Frontier
Deal found 4/26![Frontier logo]()
$94
Find flight deals from Durham to South Carolina
Keep the following information in mind while searching for Durham to South Carolina flight deals. Data was last updated Kwiecień 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $149 (Kiwi.com) |
One-way from | $74 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Durham to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated Kwiecień 29, 2026.
Use the filters below to find and compare flights from Durham to South Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RaleighCharlotte
RDU - CLT
RDUCLT
Raleigh-Durham
pt. 5/15
8:52 pm-12:05 pm
1 stop15h 13m
Charlotte Douglas
wt. 5/19
7:57 pm-9:21 am
1 stop13h 24m
$175
RaleighMyrtle Beach
RDU - MYR
RDUMYR
Raleigh-Durham
pt. 6/12
10:36 pm-11:39 am
1 stop13h 03m
Myrtle Beach Intl
pt. 6/19
9:05 pm-9:20 pm
1 stop24h 15m
$224
RaleighMyrtle Beach
RDU - MYR
RDUMYR
Raleigh-Durham
sob. 9/12
9:48 am-8:08 pm
1 stop10h 20m
Myrtle Beach Intl
śr. 9/16
1:36 pm-10:02 am
2 stops20h 26m
$252
RaleighSavannah
RDU - SAV
RDUSAV
Raleigh-Durham
wt. 8/18
10:59 am-6:20 pm
1 stop7h 21m
Savannah/Hilton Head
śr. 8/19
10:55 am-4:46 pm
1 stop5h 51m
$253
RaleighGreenville
RDU - GSP
RDUGSP
Raleigh-Durham
śr. 5/27
10:32 am-2:20 pm
1 stop3h 48m
Greenville
śr. 6/3
10:30 am-2:08 pm
1 stop3h 38m
$287
RaleighSavannah
RDU - SAV
RDUSAV
Raleigh-Durham
wt. 6/9
9:59 am-5:03 pm
1 stop7h 04m
Savannah/Hilton Head
śr. 6/10
10:42 am-6:44 pm
1 stop8h 02m
$291
RaleighGreenville
RDU - GSP
RDUGSP
Raleigh-Durham
śr. 5/20
5:20 am-9:04 am
1 stop3h 44m
Greenville
czw. 5/21
5:40 am-11:52 am
1 stop6h 12m
$299
RaleighGreenville
RDU - GSP
RDUGSP
Raleigh-Durham
ndz. 5/24
11:47 am-3:44 pm
1 stop27h 57m
Greenville
pt. 5/29
5:05 pm-8:04 am
2 stops14h 59m
$302
RaleighSavannah
RDU - SAV
RDUSAV
Raleigh-Durham
pon. 5/25
9:56 am-1:10 pm
1 stop3h 14m
Savannah/Hilton Head
śr. 5/27
5:30 am-8:51 am
1 stop3h 21m
$303
RaleighSavannah
RDU - SAV
RDUSAV
Raleigh-Durham
pon. 6/1
10:32 am-2:43 pm
1 stop4h 11m
Savannah/Hilton Head
śr. 6/3
9:50 am-2:08 pm
1 stop4h 18m
$303
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Durham to South Carolina
Have a flexible travel schedule? Discover the best time to fly to South Carolina from Durham with our price prediction graph.
RDU-CLT
RDU-SAV
RDU-GSP
RDU-MYR
RDU-CHS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Durham to South Carolina
DU8-USSC
RDU-CLT
RDU-SAV
RDU-GSP
RDU-MYR
How much does it cost to fly round-trip from Durham to South Carolina?
Reviews of airlines servicing South Carolina
Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated Kwiecień 29, 2026.
Get a feel of what it's like to fly with Breeze Airways,Delta, andAmerican Airlines from Durham to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.7
Overall
8.1
Boarding
8.3
Food
6.6
Entertainment
6.6
Comfort
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Crew
8.7
Overall
8.1
Boarding
8.3
Food
6.6
Entertainment
6.6
Comfort
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Crew
8.7
Overall
8.1
Boarding
8.3
Food
6.6
Entertainment
6.6
Comfort
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Crew
8.7
Overall
8.1
Boarding
8.3
Food
6.6
Entertainment
6.6
Comfort
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Related info for your journey
Find useful and relevant information for your journey from Durham to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Durham to South Carolina
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to South Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Durham to South Carolina by cabin class
Find flights from Durham to South Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Durham and South Carolina flights
Browse other Durham and South Carolina flight options. Last updated on Kwiecień 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from South Carolina
Find the right flight back to Durham after your stay in South Carolina
Durham to South Carolina flights
Consider these flights traveling from Durham to South Carolina.
Top 3 airlines flying from Durham to South Carolina
Discover the top 3 airlines that operate flights from Durham to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated Kwiecień 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$54 | Average$287 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$196 | Average$404 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$283 | Average$437 | FlexibilityNo cancel fee | On-timeN/A |