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Durham

$96+ Cheap flights from Santa Ana, CA (SNA) to Durham, NC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/25. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — RDU
Mar 7 — Mar 141
Sat 3/7
Sat 3/14
1 adult, Economy
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Cheap flight deals from Santa Ana to Durham

Cheapest flights from Santa Ana to Durham
Explore the most affordable flight options available from Santa Ana to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 5, 2026.

This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/171:27 pm
SNA
-
RDU
1 stop6h 34m
United Airlines
Wed 3/189:00 am
RDU
-
SNA
1 stop11h 28m
United Airlines
Deal found 2/3$252
This American Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/411:41 am
SNA
-
RDU
1 stop9h 18m
American Airlines
Wed 3/114:28 pm
RDU
-
SNA
1 stop8h 11m
American Airlines
Deal found 2/5$257
This Expedia deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2112:25 pm
SNA
-
RDU
1 stop27h 28m
Multiple Airlines
Tue 2/246:51 pm
RDU
-
SNA
1 stop18h 37m
Multiple Airlines
Deal found 2/2$260
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1710:52 am
SNA
-
RDU
2 stops9h 52m
United Airlines
Tue 3/246:30 am
RDU
-
SNA
1 stop7h 57m
United Airlines
Deal found 2/3$262
This Alaska Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1711:31 am
SNA
-
RDU
1 stop15h 39m
Alaska Airlines
Tue 3/247:35 am
RDU
-
SNA
1 stop11h 54m
Alaska Airlines
Deal found 2/3$277
This CheapOair deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2011:31 am
SNA
-
RDU
1 stop25h 45m
Frontier
Sun 2/227:38 pm
RDU
-
SNA
1 stop18h 08m
Frontier
Deal found 2/2$280
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:45 am
SNA
-
RDU
1 stop7h 32m
United Airlines
Wed 3/254:50 pm
RDU
-
SNA
1 stop7h 55m
United Airlines
Deal found 2/4$288
This United Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/411:10 am
SNA
-
RDU
2 stops9h 34m
United Airlines
Wed 3/114:50 pm
RDU
-
SNA
1 stop7h 55m
United Airlines
Deal found 2/5$291
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2711:32 am
SNA
-
RDU
1 stop26h 33m
Multiple Airlines
Mon 5/188:18 am
RDU
-
SNA
2 stops34h 05m
Multiple Airlines
Deal found 2/3$293
This Southwest deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/172:05 pm
SNA
-
RDU
1 stop6h 50m
Southwest
Tue 3/245:40 am
RDU
-
SNA
2 stops9h 30m
Southwest
Deal found 2/2$302

Find flight deals from Santa Ana to Durham

Keep the following information in mind while searching for Santa Ana to Durham flight deals. Data was last updated February 5, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$252
(United Airlines)

One-way from

$96
(Travelocity)

Popular in

November

Cheapest in

August

Average price

$421
Provider with most accurate pricing for Los Angeles-Raleigh-Durham flight deals.
Search Deals
Provider most trusted by Cheapflights users for Los Angeles-Raleigh-Durham flights.
Search Deals
From Santa Ana J. Wayne/Orange Cnty to Durham
Search Deals
One-way flight from Santa Ana J. Wayne/Orange Cnty to Durham
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($30 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Ana to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 5, 2026.
Use the filters below to find and compare flights from Santa Ana to Durham that are best for you.

Fly from

Santa Ana

Fly to

Durham

Route

Depart

Return

Price

Santa AnaRaleigh

SNA - RDU

SNARDU

Santa Ana J. Wayne/Orange Cnty

Tue 3/17

1:27 pm-11:01 pm

1 stop6h 34m

Raleigh-Durham

Wed 3/18

9:00 am-5:28 pm

1 stop11h 28m

$252

Santa AnaRaleigh

SNA - RDU

SNARDU

Santa Ana J. Wayne/Orange Cnty

Tue 3/17

10:52 am-11:44 pm

2 stops9h 52m

Raleigh-Durham

Tue 3/24

6:30 am-11:27 am

1 stop7h 57m

$262

Santa AnaRaleigh

SNA - RDU

SNARDU

Santa Ana J. Wayne/Orange Cnty

Tue 3/17

11:31 am-6:10 am

1 stop15h 39m

Raleigh-Durham

Tue 3/24

7:35 am-4:29 pm

1 stop11h 54m

$277

Santa AnaRaleigh

SNA - RDU

SNARDU

Santa Ana J. Wayne/Orange Cnty

Fri 2/20

11:31 am-4:16 pm

1 stop25h 45m

Raleigh-Durham

Sun 2/22

7:38 pm-10:46 am

1 stop18h 08m

$280

Santa AnaRaleigh

SNA - RDU

SNARDU

Santa Ana J. Wayne/Orange Cnty

Wed 3/4

11:10 am-11:44 pm

2 stops9h 34m

Raleigh-Durham

Wed 3/11

4:50 pm-9:45 pm

1 stop7h 55m

$291

Santa AnaRaleigh

SNA - RDU

SNARDU

Santa Ana J. Wayne/Orange Cnty

Mon 4/27

11:32 am-5:05 pm

1 stop26h 33m

Raleigh-Durham

Mon 5/18

8:18 am-3:23 pm

2 stops34h 05m

$293

Santa AnaRaleigh

SNA - RDU

SNARDU

Santa Ana J. Wayne/Orange Cnty

Tue 3/17

2:05 pm-11:55 pm

1 stop6h 50m

Raleigh-Durham

Tue 3/24

5:40 am-12:10 pm

2 stops9h 30m

$302

Santa AnaRaleigh

SNA - RDU

SNARDU

Santa Ana J. Wayne/Orange Cnty

Thu 2/26

11:15 am-11:47 pm

1 stop9h 32m

Raleigh-Durham

Mon 3/2

4:50 pm-10:22 pm

1 stop8h 32m

$337

Santa AnaRaleigh

SNA - RDU

SNARDU

Santa Ana J. Wayne/Orange Cnty

Mon 6/1

1:04 pm-9:09 pm

Nonstop5h 05m

Raleigh-Durham

Thu 6/4

7:26 pm-9:56 am

1 stop17h 30m

$349

Santa AnaRaleigh

SNA - RDU

SNARDU

Santa Ana J. Wayne/Orange Cnty

Fri 2/20

11:31 am-4:16 pm

1 stop25h 45m

Raleigh-Durham

Mon 2/23

5:10 pm-3:42 pm

2 stops25h 32m

$353

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/2

Showing 1-10 of 22 results
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Best time to book a flight from Santa Ana to Durham

Have a flexible travel schedule? Discover the best time to fly to Durham from Santa Ana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to Durham

How far ahead should I book a flight from Santa Ana, California to Durham?

Use this chart to determine the optimal time to book a round-trip flight from Santa Ana to Durham. Price data was last updated on January 30, 2026.

The price you pay for your flight from Santa Ana, California to Durham may vary depending on when you book. For the best chance of a lower fare, look to book 65 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Santa Ana, California to Durham?

Currently, March is the cheapest month in which you can book a flight from Santa Ana, California to Durham (average of $129). Flying from Santa Ana, California to Durham in June is currently the most expensive (average of $233). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Durham

Get insights into the airlines that provide service to Durham. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Durham. Reviews last updated February 5, 2026.
See what other customers who have flown with Southwest, Delta, and United Airlines from Santa Ana to Durham have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,275 reviews

Boarding

8.1

Crew

8.6

Overall

8.0

Food

7.0

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
Southwest
8.0
Very good
4,275 reviews
Southwest
8.0
Very good
4,275 reviews

Boarding

8.1

Crew

8.6

Overall

8.0

Food

7.0

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
Delta
7.9
Good
8,151 reviews
Southwest
8.0
Very good
4,275 reviews

Boarding

8.1

Crew

8.6

Overall

8.0

Food

7.0

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
United Airlines
7.4
Good
9,240 reviews
Southwest
8.0
Very good
4,275 reviews

Boarding

8.1

Crew

8.6

Overall

8.0

Food

7.0

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
American Airlines
7.2
Good
11,237 reviews
Southwest
8.0
Very good
4,275 reviews

Boarding

8.1

Crew

8.6

Overall

8.0

Food

7.0

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Related info for your journey

Find useful and relevant information for your journey from Santa Ana to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Santa Ana to Durham?

    Santa Ana J. Wayne/Orange Cnty (SNA) is the airport you will fly out of if you book a flight from Santa Ana to Durham. You should not have trouble finding flights to Durham from J. Wayne/Orange Cnty; the airport handles an average of 0 outbound flights to Durham per day. You should also have plenty of airline options to choose from since 4 airlines have flights from the Santa Ana airport to Durham. It is only a 4.8 mi journey to J. Wayne/Orange Cnty (SNA) from Santa Ana’s city center.

  • How long is the flight from Santa Ana, California to Durham?

    A quick flight from Santa Ana, California to Durham can take about 6h 34m. United Airlines provides one of the quickest options available for as low as $252. The distance from Santa Ana, California to Durham is about 2207 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Santa Ana, California to Durham one-way?

    To fly one-way, consider booking your trip with American Airlines, which is currently one of the cheapest options available, starting at $97. Breeze Airways flights start at $114 while deals on Southwest start at $144 one-way.

  • Can I find deals for flights from Santa Ana to Durham that include hotel bookings?

    Yes. In addition to deals on Santa Ana to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Ana to Durham?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to Durham.

  • Can I find deals for business class flights from Santa Ana to Durham?

    Yes. Cheapflights offers flight deals from Santa Ana to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Ana, California to Durham?

    Currently, March is the cheapest month in which you can book a flight from Santa Ana, California to Durham (average of $129). Flying from Santa Ana, California to Durham in June is currently the most expensive (average of $233). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Santa Ana to Durham

Discover the top 4 airlines that operate flights from Santa Ana to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 5, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$208Average$456FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$250Average$459FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$322Average$456FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$338Average$425FlexibilityNo cancel feeOn-time69%

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