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Durham

$92+ Cheap flights from Odessa, TX to Durham, NC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/1. Fares are subject to change and may not be available on all flights or dates of travel.
MAF — RDU
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Odessa to Durham

Keep the following information in mind while searching for Odessa to Durham flight deals. Data was last updated September 15, 2025.

Round-trip from

$489
(United Airlines)

One-way from

$92
(Southwest)

Popular in

March

Cheapest in

June

Average price

$287
From Odessa to Durham
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One-way flight from Odessa to Durham
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Highest demand for flights based on searches. 12% potential increase in price ($54 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Odessa to Durham

Cheapest flights from Odessa to Durham
Explore the most affordable flight options available from Odessa to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/235:00 amMAF - RDU
1 stop5h 31mUnited Airlines
Thu 10/235:04 pmRDU - MAF
1 stop7h 10mUnited Airlines
Deal found 9/14$489
This United Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/225:00 amMAF - RDU
1 stop5h 31mUnited Airlines
Sun 10/266:00 amRDU - MAF
1 stop6h 24mUnited Airlines
Deal found 9/14$702

Cheapflights Fare Finder

 
Customize your flight search to find flights from Odessa to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Odessa to Durham that are best for you.

Fly from

Odessa

Fly to

Durham

Route

Depart

Return

Price

MidlandRaleigh

MAF - RDU

MAFRDU

Midland Intl

Thu 10/23

5:00 am-11:31 am

1 stop5h 31m

Raleigh-Durham

Thu 10/23

5:04 pm-11:14 pm

1 stop7h 10m

$489

MidlandRaleigh

MAF - RDU

MAFRDU

Midland Intl

Wed 10/22

5:00 am-11:31 am

1 stop5h 31m

Raleigh-Durham

Sun 10/26

6:00 am-11:24 am

1 stop6h 24m

$702

MidlandRaleigh

MAF - RDU

MAFRDU

Midland Intl

Wed 10/1

11:35 am-6:45 pm

1 stop6h 10m

$92

MidlandRaleigh

MAF - RDU

MAFRDU

Midland Intl

Sat 10/4

10:45 am-10:05 pm

1 stop10h 20m

$106

MidlandRaleigh

MAF - RDU

MAFRDU

Midland Intl

Mon 12/15

1:55 pm-10:45 pm

1 stop7h 50m

$109

MidlandRaleigh

MAF - RDU

MAFRDU

Midland Intl

Mon 10/13

5:11 pm-11:52 pm

1 stop5h 41m

$109

MidlandRaleigh

MAF - RDU

MAFRDU

Midland Intl

Wed 10/8

5:11 pm-11:52 pm

1 stop5h 41m

$109

MidlandRaleigh

MAF - RDU

MAFRDU

Midland Intl

Thu 12/4

9:00 am-2:35 pm

1 stop4h 35m

$109

MidlandRaleigh

MAF - RDU

MAFRDU

Midland Intl

Mon 11/3

5:30 am-2:06 pm

1 stop7h 36m

$109

MidlandRaleigh

MAF - RDU

MAFRDU

Midland Intl

Tue 3/3

7:05 am-1:20 pm

1 stop5h 15m

$109

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/12

Showing 1-10 of 12 results
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Best time to book a flight from Odessa to Durham

Have a flexible travel schedule? Discover the best time to fly to Durham from Odessa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Odessa to Durham
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Odessa to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Odessa to Durham?

    There are many flights that can get you from Odessa to Durham in 5h 31m. Fly via United Airlines to get the fastest option. The distance from Odessa to Durham is about 1365 mi.

  • Can I find deals for flights from Odessa to Durham that include hotel bookings?

    Yes. In addition to deals on Odessa to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Odessa to Durham?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Odessa to Durham.

  • Can I find deals for business class flights from Odessa to Durham?

    Yes. Cheapflights offers flight deals from Odessa to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Odessa to Durham?

    Currently, August is the cheapest month in which you can book a flight from Odessa to Durham (average of $206). Flying from Odessa to Durham in March is currently the most expensive (average of $293). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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