HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Durham

$72+ Cheap flights from Harrisburg (MDT) to Durham, NC

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/26. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — RDU
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Harrisburg to Durham with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Harrisburg to Durham

Keep the following information in mind while searching for Harrisburg to Durham flight deals. Data was last updated September 17, 2025.

Round-trip from

$156
(Booking.com)

One-way from

$72
(Priceline)

Popular in

March

Cheapest in

February

Average price

$298
From Harrisburg to Durham
Search Deals
One-way flight from Harrisburg to Durham
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($62 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($23 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Harrisburg to Durham

Cheapest flights from Harrisburg to Durham
Explore the most affordable flight options available from Harrisburg to Durham. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Booking.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2611:07 amMDT - RDU
1 stop22h 46mFrontier
Sun 9/288:57 pmRDU - MDT
1 stop13h 05mFrontier
Deal found 9/16$156
This Booking.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/176:31 pmMDT - RDU
1 stop23h 51mFrontier
Sun 10/199:36 pmRDU - MDT
1 stop20h 00mFrontier
Deal found 9/16$188
This Booking.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/246:31 pmMDT - RDU
1 stop15h 04mFrontier
Sun 10/269:36 pmRDU - MDT
1 stop20h 00mFrontier
Deal found 9/17$198
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/166:15 amMDT - RDU
1 stop3h 19mUnited Airlines
Sun 10/196:00 amRDU - MDT
1 stop3h 29mUnited Airlines
Deal found 9/16$229
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/146:00 amMDT - RDU
2 stops10h 43mDelta
Tue 10/215:31 pmRDU - MDT
1 stop5h 29mDelta
Deal found 9/17$231
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/14:45 pmMDT - RDU
1 stop6h 26mAmerican Airlines
Wed 10/86:00 amRDU - MDT
1 stop4h 07mAmerican Airlines
Deal found 9/15$234
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/16:10 amMDT - RDU
2 stops7h 53mDelta
Wed 10/85:27 pmRDU - MDT
1 stop5h 41mDelta
Deal found 9/15$239
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/266:23 pmMDT - RDU
1 stop5h 50mDelta
Tue 9/3010:50 amRDU - MDT
1 stop6h 38mDelta
Deal found 9/15$254
This Booking.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1911:07 amMDT - RDU
1 stop7h 01mFrontier
Sun 9/219:02 pmRDU - MDT
1 stop13h 00mFrontier
Deal found 9/17$256

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to Durham that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Harrisburg to Durham that are best for you.

Fly from

Harrisburg

Fly to

Durham

Route

Depart

Return

Price

HarrisburgRaleigh

MDT - RDU

MDTRDU

Harrisburg

Fri 9/26

11:07 am-9:53 am

1 stop22h 46m

Raleigh-Durham

Sun 9/28

8:57 pm-10:02 am

1 stop13h 05m

$156

HarrisburgRaleigh

MDT - RDU

MDTRDU

Harrisburg

Fri 10/3

11:07 am-6:08 pm

1 stop7h 01m

Raleigh-Durham

Sun 10/5

9:02 pm-10:02 am

1 stop13h 00m

$156

HarrisburgRaleigh

MDT - RDU

MDTRDU

Harrisburg

Fri 12/5

4:25 pm-11:02 pm

1 stop6h 37m

Raleigh-Durham

Mon 12/8

7:21 pm-11:50 pm

1 stop4h 29m

$229

HarrisburgRaleigh

MDT - RDU

MDTRDU

Harrisburg

Thu 10/16

6:15 am-9:34 am

1 stop3h 19m

Raleigh-Durham

Sun 10/19

6:00 am-9:29 am

1 stop3h 29m

$229

HarrisburgRaleigh

MDT - RDU

MDTRDU

Harrisburg

Tue 10/14

6:00 am-4:43 pm

2 stops10h 43m

Raleigh-Durham

Tue 10/21

5:31 pm-11:00 pm

1 stop5h 29m

$231

HarrisburgRaleigh

MDT - RDU

MDTRDU

Harrisburg

Wed 10/1

6:10 am-2:03 pm

2 stops7h 53m

Raleigh-Durham

Wed 10/8

5:27 pm-11:08 pm

1 stop5h 41m

$239

HarrisburgRaleigh

MDT - RDU

MDTRDU

Harrisburg

Sat 9/27

2:43 pm-6:39 pm

1 stop3h 56m

Raleigh-Durham

Tue 9/30

10:36 am-1:54 pm

1 stop3h 18m

$254

HarrisburgRaleigh

MDT - RDU

MDTRDU

Harrisburg

Fri 9/26

6:23 pm-12:13 am

1 stop5h 50m

Raleigh-Durham

Tue 9/30

10:50 am-5:28 pm

1 stop6h 38m

$254

HarrisburgRaleigh

MDT - RDU

MDTRDU

Harrisburg

Sat 9/27

6:00 am-11:14 am

1 stop5h 14m

Raleigh-Durham

Tue 9/30

10:50 am-5:28 pm

1 stop6h 38m

$254

HarrisburgRaleigh

MDT - RDU

MDTRDU

Harrisburg

Fri 9/26

6:23 pm-12:13 am

1 stop5h 50m

Raleigh-Durham

Wed 10/1

6:56 pm-11:46 pm

1 stop4h 50m

$254

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 18 results
1
2

Best time to book a flight from Harrisburg to Durham

Have a flexible travel schedule? Discover the best time to fly to Durham from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Durham

What is the cheapest month to book a flight from Harrisburg to Durham?

Currently, August is the cheapest month in which you can book a flight from Harrisburg to Durham (average of $206). Flying from Harrisburg to Durham in March is currently the most expensive (average of $293). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDT to DU8?

Find hourly flight availability from Harrisburg to Durham. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Harrisburg to Durham as you normally would.

What is the cheapest day to fly from Harrisburg to Durham?

Use this chart to determine the cheapest time to fly round-trip from Harrisburg to Durham. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Harrisburg to Durham flight should consider departing on Thursday afternoons when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Durham

Get insights into the airlines that provide service to Durham. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Durham. Reviews last updated September 17, 2025.
Read through reviews of airlines operating flights from Harrisburg to Durham, such as United Airlines and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,926 reviews

Entertainment

7.1

Food

6.6

Comfort

7.3

Overall

7.4

Boarding

7.7

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Julia,Sep 2025

BUF - DEN

The staff were amazing, from check in to boarding and on the flight. The range of entertainment options were really good as well.
United Airlines
7.4
Good
8,926 reviews
United Airlines
7.4
Good
8,926 reviews

Entertainment

7.1

Food

6.6

Comfort

7.3

Overall

7.4

Boarding

7.7

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Julia,Sep 2025

BUF - DEN

The staff were amazing, from check in to boarding and on the flight. The range of entertainment options were really good as well.
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,926 reviews

Entertainment

7.1

Food

6.6

Comfort

7.3

Overall

7.4

Boarding

7.7

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Julia,Sep 2025

BUF - DEN

The staff were amazing, from check in to boarding and on the flight. The range of entertainment options were really good as well.

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Durham. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Harrisburg to Durham?

    Harrisburg (MDT), located 8.5 mi from the city center, is the airport you fly out of when you book flights from Harrisburg to Durham. 2 airlines have flights from Harrisburg to Durham on a regular basis. Booking flights from Harrisburg to Durham should not be difficult; the airport handles an average of 0 outbound flights to Durham per day.

  • How long is the flight from Harrisburg to Durham?

    A quick flight from Harrisburg to Durham can take about 3h 19m. Frontier provides one of the quickest options available for as low as $229. The distance between Harrisburg and Durham is about 318 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Harrisburg to Durham one-way?

    One-way options have recently been found by users for as low as $72 on Frontier. Other airlines that offer cheap prices include American Airlines from $197 and United Airlines from $197 one-way.

  • Can I find deals for flights from Harrisburg to Durham that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Durham flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Durham?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Durham.

  • Can I find deals for business class flights from Harrisburg to Durham?

    Yes. Cheapflights offers flight deals from Harrisburg to Durham by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to Durham?

    Currently, August is the cheapest month in which you can book a flight from Harrisburg to Durham (average of $206). Flying from Harrisburg to Durham in March is currently the most expensive (average of $293). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Harrisburg to Durham

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Charlotte flights
John F Kennedy Intl to Raleigh flights
LaGuardia to Raleigh flights
LaGuardia to Charlotte flights
Newark to Raleigh flights
Newark to Charlotte flights
Dulles Intl to Charlotte flights
John F Kennedy Intl to Norfolk flights
Newark to Myrtle Beach flights
Newark to Norfolk flights
LaGuardia to Norfolk flights
Philadelphia to Charlotte flights
John F Kennedy Intl to Myrtle Beach flights
LaGuardia to Myrtle Beach flights
Philadelphia to Raleigh flights
Newark to Wilmington flights
LaGuardia to Asheville flights
LaGuardia to Knoxville flights
Dulles Intl to Raleigh flights
Newark to Asheville flights
John F Kennedy Intl to Wilmington flights
Newark to Greensboro flights
John F Kennedy Intl to Greensboro flights
LaGuardia to Greensboro flights
John F Kennedy Intl to Knoxville flights
John F Kennedy Intl to Asheville flights
LaGuardia to Wilmington flights
Reagan-National to Knoxville flights
Reagan-National to Asheville flights
Reagan-National to Raleigh flights
Dulles Intl to Knoxville flights
Newark to Knoxville flights
Philadelphia to Knoxville flights
Dulles Intl to Myrtle Beach flights
Reagan-National to Charlotte flights
Reagan-National to Myrtle Beach flights
Philadelphia to Myrtle Beach flights
Philadelphia to Greensboro flights
Pittsburgh to Charlotte flights
Allentown to Charlotte flights
Dulles Intl to Greensboro flights
Philadelphia to Asheville flights
Pittsburgh to Myrtle Beach flights
Reagan-National to Greensboro flights
Dulles Intl to Wilmington flights
Allentown to Myrtle Beach flights
Pittsburgh to Raleigh flights
Philadelphia to Wilmington flights
Philadelphia to Norfolk flights
Reagan-National to Wilmington flights

Top 2 airlines flying from Harrisburg to Durham

Discover the top 2 airlines that operate flights from Harrisburg to Durham. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$222Average$320FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$228Average$380FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.