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$352+ Cheap flights from Panama City (PTY) to Detroit Metropolitan Wayne County Airport (DTW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/6. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — DTW
Nov 27 — Dec 41
Thu 11/27
Thu 12/4
1 adult, Economy
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Cheap flight deals from Panama City to Detroit

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Detroit (DTW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$528
(Kiwi.com)

One-way from

$352
(Kiwi.com)

Popular in

September

Cheapest in

July
Provider with most accurate pricing for Panama City Tocumen Intl-Detroit Metropolitan Wayne County flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Detroit Metropolitan Wayne County flights.
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From Panama City Tocumen Intl to Detroit Metropolitan Wayne County
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One-way flight from Panama City Tocumen Intl to Detroit Metropolitan Wayne County
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Highest demand for flights based on searches. 10% potential increase in price ($95 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($27 potential savings vs. average RT price).
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Find flight deals from Panama City to Detroit

Cheapest flights from Panama City to Detroit
Explore the most affordable flight options available from Panama City to Detroit. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 28, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/29:33 pmPTY - DTW
1 stop16h 56mMultiple Airlines
Thu 12/44:39 pmDTW - PTY
2 stops24h 16mMultiple Airlines
Deal found 10/27$528
This Mytrip deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2211:25 amPTY - DTW
2 stops12h 29mMultiple Airlines
Thu 12/44:39 pmDTW - PTY
2 stops21h 21mMultiple Airlines
Deal found 10/26$555
This Mytrip deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1211:25 amPTY - DTW
3 stops20h 18mMultiple Airlines
Mon 11/177:10 amDTW - PTY
3 stops27h 20mMultiple Airlines
Deal found 10/26$561

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Detroit that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
Use the filters below to find and compare flights from Panama City to Detroit Metropolitan Wayne County Airport that are best for you.

Fly from

Panama City

Fly to

Detroit

Route

Depart

Return

Price

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Wed 11/12

11:25 am-7:43 am

3 stops20h 18m

Detroit Metropolitan Wayne County

Mon 11/17

7:10 am-10:30 am

3 stops27h 20m

$561

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Sat 11/22

8:40 am-11:54 pm

2 stops15h 14m

Detroit Metropolitan Wayne County

Thu 12/4

4:39 pm-8:06 am

1 stop15h 27m

$573

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Mon 12/1

2:55 am-11:46 pm

2 stops20h 51m

Detroit Metropolitan Wayne County

Thu 12/4

4:39 pm-8:06 am

1 stop15h 27m

$575

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Fri 12/26

8:10 am-12:42 am

1 stop16h 32m

Detroit Metropolitan Wayne County

Fri 1/2

6:00 am-2:55 pm

2 stops32h 55m

$699

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Tue 12/30

7:50 pm-12:42 am

3 stops28h 52m

$359

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Mon 12/29

7:50 pm-12:42 am

2 stops28h 52m

$363

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Wed 12/31

7:31 am-12:42 am

2 stops17h 11m

$381

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Tue 1/6

11:25 am-11:59 pm

2 stops12h 34m

$427

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Sat 3/21

3:50 pm-10:47 am

2 stops17h 57m

$441

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Sat 3/21

9:30 am-8:17 pm

1 stop9h 47m

$442

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/25

Compare providers for flights from Panama City to Detroit

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Detroit in October.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City-Detroit Metropolitan Wayne County Airport flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Panama City-Detroit Metropolitan Wayne County Airport flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Panama City-Detroit Metropolitan Wayne County Airport flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Detroit Metropolitan Wayne County Airport flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Detroit Metropolitan Wayne County Airport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Detroit

Have a flexible travel schedule? Discover the best time to fly to Detroit from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Detroit Metropolitan Wayne County Airport

What is the cheapest time of day to fly from PTY to DTW?

Find hourly flight availability from Panama City to Detroit. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 28, 2025.

When flying from Panama City to Detroit Metropolitan Wayne County Airport, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 22% versus a flight in the morning.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Detroit. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find deals for flights from Panama City to Detroit that include hotel bookings?

    Yes. In addition to deals on Panama City to Detroit flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Detroit?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Detroit.

  • Can I find deals for business class flights from Panama City to Detroit?

    Yes. Cheapflights offers flight deals from Panama City to Detroit by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

Traveling to a place near Detroit Metropolitan Wayne County Airport?

Book flights to Detroit Metropolitan Wayne County Airport if you plan to visit one of these locations
Sterling Heights
Dearborn
Warren
Southfield
Troy
Novi
Clarkston
Allen Park
Utica
Romulus
Auburn Hills
Plymouth
Monroe
Wixom
Ypsilanti
Brighton
Livonia
Roseville
Fremont
Port Huron

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