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$258+ Cheap flights from Panama City (PTY) to Detroit Metropolitan Wayne County Airport (DTW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/9. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — DTW
Aug 19 — Aug 261
Tue 8/19
Tue 8/26
1 adult, Economy
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Cheap flight deals from Panama City to Detroit

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Detroit (DTW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 14, 2025.

Round-trip from

$452
(Avianca Connect)

One-way from

$258
(Mytrip)

Popular in

October

Cheapest in

July

Average price

$772
From Panama City Tocumen Intl to Detroit Metropolitan Wayne County
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One-way flight from Panama City Tocumen Intl to Detroit Metropolitan Wayne County
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Highest demand for flights based on searches. 7% potential increase in price ($63 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($15 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Panama City to Detroit

Cheapest flights from Panama City to Detroit
Explore the most affordable flight options available from Panama City to Detroit. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

This Avianca Connect deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1910:05 pmPTY - DTW
2 stops21h 09mMultiple Airlines
Sat 10/46:41 amDTW - PTY
2 stops18h 29mMultiple Airlines
Deal found 8/14$452
This Avianca Connect deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/193:25 amPTY - DTW
2 stops15h 49mMultiple Airlines
Sat 10/46:41 amDTW - PTY
2 stops15h 29mMultiple Airlines
Deal found 8/12$457
This Avianca Connect deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/123:25 amPTY - DTW
2 stops15h 49mMultiple Airlines
Sat 9/276:41 amDTW - PTY
2 stops15h 29mMultiple Airlines
Deal found 8/14$463
This Avianca Connect deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/210:05 pmPTY - DTW
2 stops19h 35mMultiple Airlines
Thu 9/116:41 amDTW - PTY
2 stops18h 29mMultiple Airlines
Deal found 8/12$466
This Avianca Connect deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2610:05 pmPTY - DTW
2 stops21h 09mMultiple Airlines
Fri 10/36:41 amDTW - PTY
2 stops15h 29mMultiple Airlines
Deal found 8/12$467
This Avianca Connect deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/183:20 amPTY - DTW
2 stops19h 23mMultiple Airlines
Sun 10/56:17 amDTW - PTY
2 stops15h 53mMultiple Airlines
Deal found 8/14$470
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/208:10 amPTY - DTW
1 stop11h 04mMultiple Airlines
Fri 10/36:30 amDTW - PTY
1 stop10h 55mMultiple Airlines
Deal found 8/12$477
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/188:01 amPTY - DTW
1 stop11h 13mMultiple Airlines
Sat 10/46:30 amDTW - PTY
1 stop10h 55mMultiple Airlines
Deal found 8/14$483
This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/188:01 amPTY - DTW
1 stop11h 13mMultiple Airlines
Sun 10/56:17 amDTW - PTY
1 stop11h 08mMultiple Airlines
Deal found 8/14$484

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Detroit that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
Use the filters below to find and compare flights from Panama City to Detroit Metropolitan Wayne County Airport that are best for you.

Fly from

Panama City

Fly to

Detroit

Route

Depart

Return

Price

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Fri 9/19

10:05 pm-8:14 pm

2 stops21h 09m

Detroit Metropolitan Wayne County

Sat 10/4

6:41 am-12:10 am

2 stops18h 29m

$452

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Fri 9/19

3:25 am-8:14 pm

2 stops15h 49m

Detroit Metropolitan Wayne County

Sat 10/4

6:41 am-9:10 pm

2 stops15h 29m

$457

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Thu 9/25

10:05 pm-8:14 pm

2 stops21h 09m

Detroit Metropolitan Wayne County

Wed 10/15

6:41 am-9:10 pm

2 stops15h 29m

$463

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Fri 9/12

3:25 am-8:14 pm

2 stops15h 49m

Detroit Metropolitan Wayne County

Sat 9/27

6:41 am-9:10 pm

2 stops15h 29m

$463

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Tue 9/2

10:05 pm-6:40 pm

2 stops19h 35m

Detroit Metropolitan Wayne County

Thu 9/11

6:41 am-12:10 am

2 stops18h 29m

$466

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Fri 9/26

8:01 am-8:14 pm

1 stop11h 13m

Detroit Metropolitan Wayne County

Fri 10/3

6:30 am-7:29 pm

1 stop13h 59m

$467

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Thu 9/18

3:20 am-11:43 pm

2 stops19h 23m

Detroit Metropolitan Wayne County

Sun 10/5

6:17 am-9:10 pm

2 stops15h 53m

$470

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Tue 9/9

5:25 pm-8:14 pm

2 stops25h 49m

$258

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Mon 2/9

6:30 pm-2:09 pm

2 stops19h 39m

$287

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Mon 2/9

11:35 am-11:44 pm

1 stop12h 09m

$400

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/12

Showing 1-10 of 11 results
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Best time to book a flight from Panama City to Detroit

Have a flexible travel schedule? Discover the best time to fly to Detroit from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Detroit Metropolitan Wayne County Airport

What is the cheapest time of day to fly from PTY to DTW?

Find hourly flight availability from Panama City to Detroit. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 14, 2025.

When flying from Panama City to Detroit Metropolitan Wayne County Airport, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 23% versus a flight in the morning.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Detroit. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find deals for flights from Panama City to Detroit that include hotel bookings?

    Yes. In addition to deals on Panama City to Detroit flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Detroit?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Detroit.

  • Can I find deals for business class flights from Panama City to Detroit?

    Yes. Cheapflights offers flight deals from Panama City to Detroit by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Detroit Metropolitan Wayne County Airport?

    Currently, April is the cheapest month in which you can book a flight from Panama City to Detroit Metropolitan Wayne County Airport (average of $257). Flying from Panama City to Detroit Metropolitan Wayne County Airport in March is currently the most expensive (average of $305). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Detroit Metropolitan Wayne County Airport?

Book flights to Detroit Metropolitan Wayne County Airport if you plan to visit one of these locations
Sterling Heights
Warren
Troy
Dearborn
Novi
Southfield
Clarkston
Auburn Hills
Utica
Plymouth
Monroe
Wixom
Brighton
Livonia
Roseville
Fremont
Port Huron
Madison Heights
Southgate
Romulus

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