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$384+ Cheap flights from Panama City (PTY) to Detroit Metropolitan Wayne County Airport (DTW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/1. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — DTW
Feb 11 — Feb 181
Wed 2/11
Wed 2/18
1 adult, Economy
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Cheap flight deals from Panama City to Detroit

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Detroit (DTW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 12, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$533
(Kiwi.com)

One-way from

$384
(Expedia)

Popular in

December

Cheapest in

June
Provider with most accurate pricing for Panama City Tocumen Intl-Detroit Metropolitan Wayne County flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Detroit Metropolitan Wayne County flights.
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From Panama City Tocumen Intl to Detroit Metropolitan Wayne County
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One-way flight from Panama City Tocumen Intl to Detroit Metropolitan Wayne County
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Highest demand for flights based on searches. 32% potential increase in price ($408 potential increase over avg. RT price).
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Cheapest flight prices on average. 10% potential price decrease ($80 potential savings vs. average RT price).
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Find flight deals from Panama City to Detroit

Cheapest flights from Panama City to Detroit
Explore the most affordable flight options available from Panama City to Detroit. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 12, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/3110:26 am
PTY
-
DTW
1 stop11h 42m
Multiple Airlines
Sat 2/75:05 am
DTW
-
PTY
1 stop15h 29m
Multiple Airlines
Deal found 1/10$533
This Kiwi.com deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/295:50 pm
PTY
-
DTW
2 stops18h 11m
Multiple Airlines
Mon 2/92:47 pm
DTW
-
PTY
1 stop29h 50m
Multiple Airlines
Deal found 1/12$534
This Kiwi.com deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/299:33 pm
PTY
-
DTW
1 stop14h 28m
Multiple Airlines
Tue 2/102:47 pm
DTW
-
PTY
2 stops18h 03m
Multiple Airlines
Deal found 1/12$543
This Kiwi.com deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/25:50 pm
PTY
-
DTW
2 stops28h 22m
Multiple Airlines
Sun 2/811:00 am
DTW
-
PTY
1 stop9h 34m
Multiple Airlines
Deal found 1/10$547
This Avianca Connect deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/312:55 am
PTY
-
DTW
2 stops21h 04m
Multiple Airlines
Sat 2/75:30 am
DTW
-
PTY
2 stops19h 30m
Multiple Airlines
Deal found 1/10$548
This Kiwi.com deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/25:50 pm
PTY
-
DTW
2 stops28h 22m
Multiple Airlines
Sat 2/711:00 am
DTW
-
PTY
1 stop9h 34m
Multiple Airlines
Deal found 1/10$553
This Kiwi.com deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/410:25 am
PTY
-
DTW
1 stop11h 47m
Multiple Airlines
Tue 2/102:47 pm
DTW
-
PTY
2 stops18h 03m
Multiple Airlines
Deal found 1/12$555
This Kiwi.com deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/3012:03 pm
PTY
-
DTW
1 stop11h 56m
Multiple Airlines
Mon 2/92:47 pm
DTW
-
PTY
2 stops18h 03m
Multiple Airlines
Deal found 1/12$563
This Kiwi.com deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/39:45 am
PTY
-
DTW
2 stops12h 27m
Multiple Airlines
Tue 2/105:30 am
DTW
-
PTY
1 stop14h 49m
Multiple Airlines
Deal found 1/12$565
This Avianca Connect deal was found by Cheapflights users on 1/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/159:45 am
PTY
-
DTW
2 stops12h 27m
Multiple Airlines
Sun 1/186:35 am
DTW
-
PTY
2 stops18h 25m
Multiple Airlines
Deal found 1/10$567
This Kiwi.com deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/39:45 am
PTY
-
DTW
2 stops12h 27m
Multiple Airlines
Mon 2/98:00 am
DTW
-
PTY
1 stop12h 19m
Multiple Airlines
Deal found 1/12$570

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Detroit that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 12, 2026.
Use the filters below to find and compare flights from Panama City to Detroit Metropolitan Wayne County Airport that are best for you.

Fly from

Panama City

Fly to

Detroit

Route

Depart

Return

Price

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Sat 1/31

10:26 am-10:08 pm

1 stop11h 42m

Detroit Metropolitan Wayne County

Sat 2/7

5:05 am-8:34 pm

1 stop15h 29m

$533

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Mon 2/2

5:50 pm-10:12 pm

2 stops28h 22m

Detroit Metropolitan Wayne County

Sun 2/8

11:00 am-8:34 pm

1 stop9h 34m

$547

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Sat 1/31

2:55 am-11:59 pm

2 stops21h 04m

Detroit Metropolitan Wayne County

Sat 2/7

5:30 am-1:00 am

2 stops19h 30m

$548

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Mon 2/2

5:50 pm-10:12 pm

2 stops28h 22m

Detroit Metropolitan Wayne County

Sat 2/7

11:00 am-8:34 pm

1 stop9h 34m

$553

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Tue 2/3

9:45 am-10:12 pm

2 stops12h 27m

Detroit Metropolitan Wayne County

Tue 2/10

5:30 am-8:19 pm

1 stop14h 49m

$565

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Tue 2/3

9:45 am-10:12 pm

2 stops12h 27m

Detroit Metropolitan Wayne County

Mon 2/9

8:00 am-8:19 pm

1 stop12h 19m

$570

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Thu 1/29

9:33 pm-12:01 pm

1 stop14h 28m

Detroit Metropolitan Wayne County

Mon 2/9

8:00 am-8:19 pm

1 stop12h 19m

$612

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Fri 1/30

12:03 pm-11:59 pm

1 stop11h 56m

Detroit Metropolitan Wayne County

Wed 2/4

6:09 am-8:37 pm

2 stops14h 28m

$617

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Sun 2/1

7:50 pm-11:56 pm

2 stops28h 06m

$384

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Sat 3/21

7:50 pm-11:47 pm

2 stops50h 57m

$395

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/12

Showing 1-10 of 13 results
1
2

Compare providers for flights from Panama City to Detroit

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Detroit in January.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City-Detroit Metropolitan Wayne County Airport flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Panama City-Detroit Metropolitan Wayne County Airport flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Panama City-Detroit Metropolitan Wayne County Airport flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Detroit Metropolitan Wayne County Airport flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Detroit Metropolitan Wayne County Airport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Detroit

Have a flexible travel schedule? Discover the best time to fly to Detroit from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Detroit. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find deals for flights from Panama City to Detroit that include hotel bookings?

    Yes. In addition to deals on Panama City to Detroit flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Detroit?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Detroit.

  • Can I find deals for business class flights from Panama City to Detroit?

    Yes. Cheapflights offers flight deals from Panama City to Detroit by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

Traveling to a place near Detroit Metropolitan Wayne County Airport?

Book flights to Detroit Metropolitan Wayne County Airport if you plan to visit one of these locations
Sterling Heights
Southfield
Dearborn
Troy
Warren
Auburn Hills
Allen Park
Clarkston
Utica
Rochester Hills
Roseville
Romulus
Monroe
Wixom
Ypsilanti
Brighton
Livonia
Plymouth
Fremont
Port Huron

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