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$242+ Cheap flights from Panama City (PTY) to Detroit Metropolitan Wayne County Airport (DTW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/7. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — DTW
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Panama City to Detroit

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Detroit (DTW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2025.

Round-trip from

$490
(Avianca Connect)

One-way from

$242
(Kiwi.com)

Popular in

October

Cheapest in

July
From Panama City Tocumen Intl to Detroit Metropolitan Wayne County
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One-way flight from Panama City Tocumen Intl to Detroit Metropolitan Wayne County
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Highest demand for flights based on searches. 9% potential increase in price ($78 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($18 potential savings vs. average RT price).
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Find flight deals from Panama City to Detroit

Cheapest flights from Panama City to Detroit
Explore the most affordable flight options available from Panama City to Detroit. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Avianca Connect deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/102:55 pmPTY - DTW
2 stops23h 14mMultiple Airlines
Mon 1/198:00 amDTW - PTY
2 stops16h 40mMultiple Airlines
Deal found 9/16$490
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2812:03 pmPTY - DTW
1 stop10h 27mMultiple Airlines
Sun 11/25:43 amDTW - PTY
1 stop13h 36mMultiple Airlines
Deal found 9/17$505
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/295:55 pmPTY - DTW
2 stops25h 05mMultiple Airlines
Mon 11/36:17 amDTW - PTY
1 stop9h 37mMultiple Airlines
Deal found 9/17$516
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/275:55 pmPTY - DTW
2 stops37h 25mMultiple Airlines
Mon 11/36:17 amDTW - PTY
1 stop9h 37mMultiple Airlines
Deal found 9/17$519
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/299:33 pmPTY - DTW
1 stop21h 27mMultiple Airlines
Sun 11/27:05 amDTW - PTY
2 stops17h 55mMultiple Airlines
Deal found 9/17$527
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2710:25 amPTY - DTW
1 stop8h 35mMultiple Airlines
Sun 11/25:17 amDTW - PTY
1 stop9h 37mMultiple Airlines
Deal found 9/17$551
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/295:55 pmPTY - DTW
2 stops25h 05mMultiple Airlines
Sat 11/17:22 amDTW - PTY
1 stop13h 21mMultiple Airlines
Deal found 9/17$560

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Detroit that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Panama City to Detroit Metropolitan Wayne County Airport that are best for you.

Fly from

Panama City

Fly to

Detroit

Route

Depart

Return

Price

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Wed 12/10

2:55 pm-2:09 pm

2 stops23h 14m

Detroit Metropolitan Wayne County

Mon 1/19

8:00 am-12:40 am

2 stops16h 40m

$490

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Tue 10/28

12:03 pm-11:30 pm

1 stop10h 27m

Detroit Metropolitan Wayne County

Sun 11/2

5:43 am-7:19 pm

1 stop13h 36m

$505

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Wed 10/29

5:55 pm-8:00 pm

2 stops25h 05m

Detroit Metropolitan Wayne County

Mon 11/3

6:17 am-3:54 pm

1 stop9h 37m

$516

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Mon 10/27

5:55 pm-8:20 am

2 stops37h 25m

Detroit Metropolitan Wayne County

Mon 11/3

6:17 am-3:54 pm

1 stop9h 37m

$519

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Mon 10/27

10:25 am-8:00 pm

1 stop8h 35m

Detroit Metropolitan Wayne County

Sun 11/2

5:17 am-2:54 pm

1 stop9h 37m

$551

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Sun 10/26

2:55 am-8:00 pm

2 stops16h 05m

Detroit Metropolitan Wayne County

Sat 11/1

7:22 am-7:43 pm

1 stop13h 21m

$605

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Tue 10/7

5:25 pm-12:45 am

3 stops30h 20m

$242

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Sun 10/5

1:30 pm-8:00 pm

3 stops29h 30m

$271

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Mon 2/9

5:55 pm-2:09 pm

2 stops20h 14m

$272

Panama CityDetroit

PTY - DTW

PTYDTW

Panama City Tocumen Intl

Mon 9/29

10:05 pm-8:14 pm

2 stops21h 09m

$277

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/17

Best time to book a flight from Panama City to Detroit

Have a flexible travel schedule? Discover the best time to fly to Detroit from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Detroit Metropolitan Wayne County Airport

What is the cheapest time of day to fly from PTY to DTW?

Find hourly flight availability from Panama City to Detroit. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

When flying from Panama City to Detroit Metropolitan Wayne County Airport, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 23% versus a flight in the morning.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Detroit. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find deals for flights from Panama City to Detroit that include hotel bookings?

    Yes. In addition to deals on Panama City to Detroit flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Detroit?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Detroit.

  • Can I find deals for business class flights from Panama City to Detroit?

    Yes. Cheapflights offers flight deals from Panama City to Detroit by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Detroit Metropolitan Wayne County Airport?

    Currently, August is the cheapest month in which you can book a flight from Panama City to Detroit Metropolitan Wayne County Airport (average of $250). Flying from Panama City to Detroit Metropolitan Wayne County Airport in March is currently the most expensive (average of $305). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Detroit Metropolitan Wayne County Airport?

Book flights to Detroit Metropolitan Wayne County Airport if you plan to visit one of these locations
Sterling Heights
Dearborn
Troy
Warren
Southfield
Novi
Clarkston
Allen Park
Utica
Plymouth
Monroe
Wixom
Brighton
Livonia
Roseville
Fremont
Port Huron
Auburn Hills
Madison Heights
Southgate

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