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$99+ Cheap flights from Knoxville to Detroit Metropolitan Wayne County Airport (TYS - DTW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/13. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — DTW
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Knoxville to Detroit

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Detroit (DTW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$234
(Kiwi.com)

One-way from

$99
(Kiwi.com)

Popular in

January

Cheapest in

December

Average price

$429

Good round-trip deal

$359 or less

Good one-way deal

$248 or less
From Knoxville McGhee Tyson to Detroit Metropolitan Wayne County
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One-way flight from Knoxville McGhee Tyson to Detroit Metropolitan Wayne County
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Highest demand for flights based on searches. 0% potential increase in price ($1 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Knoxville McGhee Tyson to Detroit Metropolitan Wayne County.
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Price to beat on a one-way flight from Knoxville McGhee Tyson to Detroit Metropolitan Wayne County.
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Find flight deals from Knoxville to Detroit

Cheapest flights from Knoxville to Detroit
Explore the most affordable flight options available from Knoxville to Detroit. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/266:24 pmTYS - DTW
2 stops20h 22mMultiple Airlines
Tue 9/307:10 pmDTW - TYS
1 stop16h 45mMultiple Airlines
Deal found 9/10$234
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/191:22 pmTYS - DTW
1 stop19h 18mMultiple Airlines
Mon 9/228:49 pmDTW - TYS
1 stop16h 06mMultiple Airlines
Deal found 9/9$242
This Frontier deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/258:40 pmTYS - DTW
2 stops13h 19mFrontier
Mon 9/296:10 amDTW - TYS
1 stop13h 35mFrontier
Deal found 9/10$251
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2711:08 amTYS - DTW
2 stops11h 21mMultiple Airlines
Tue 9/307:10 pmDTW - TYS
1 stop16h 45mMultiple Airlines
Deal found 9/10$253
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/255:55 pmTYS - DTW
1 stop16h 15mMultiple Airlines
Mon 9/298:49 pmDTW - TYS
1 stop16h 40mMultiple Airlines
Deal found 9/10$260
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/135:26 pmTYS - DTW
1 stop16h 28mMultiple Airlines
Tue 10/148:20 pmDTW - TYS
1 stop15h 35mMultiple Airlines
Deal found 9/9$267
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/237:30 amTYS - DTW
1 stop24h 27mMultiple Airlines
Fri 9/265:51 pmDTW - TYS
1 stop16h 27mMultiple Airlines
Deal found 9/9$269
This Booking.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/258:40 pmTYS - DTW
1 stop28h 06mFrontier
Sun 9/286:10 amDTW - TYS
1 stop10h 08mFrontier
Deal found 9/10$275
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/111:01 pmTYS - DTW
1 stop10h 24mAmerican Airlines
Sat 10/187:00 amDTW - TYS
1 stop7h 33mAmerican Airlines
Deal found 9/11$279
This Kiwi.com deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/204:31 pmTYS - DTW
2 stops16h 09mMultiple Airlines
Mon 9/228:49 pmDTW - TYS
1 stop16h 06mMultiple Airlines
Deal found 9/8$291

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Detroit that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Knoxville to Detroit Metropolitan Wayne County Airport that are best for you.

Fly from

Knoxville

Fly to

Detroit

Route

Depart

Return

Price

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Fri 9/26

6:24 pm-2:46 pm

2 stops20h 22m

Detroit Metropolitan Wayne County

Tue 9/30

7:10 pm-11:55 am

1 stop16h 45m

$234

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Fri 9/19

1:22 pm-8:40 am

1 stop19h 18m

Detroit Metropolitan Wayne County

Mon 9/22

8:49 pm-12:55 pm

1 stop16h 06m

$242

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Sat 9/27

4:31 pm-11:43 pm

1 stop7h 12m

Detroit Metropolitan Wayne County

Tue 9/30

7:10 pm-11:55 am

1 stop16h 45m

$260

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Mon 10/13

5:26 pm-9:54 am

1 stop16h 28m

Detroit Metropolitan Wayne County

Tue 10/14

8:20 pm-11:55 am

1 stop15h 35m

$267

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Thu 9/25

8:40 pm-12:46 am

1 stop28h 06m

Detroit Metropolitan Wayne County

Sun 9/28

6:10 am-4:18 pm

1 stop10h 08m

$275

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Sat 10/11

1:01 pm-11:25 pm

1 stop10h 24m

Detroit Metropolitan Wayne County

Sat 10/18

7:00 am-2:33 pm

1 stop7h 33m

$279

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Wed 9/24

4:31 pm-10:10 am

1 stop17h 39m

Detroit Metropolitan Wayne County

Sun 9/28

7:35 pm-5:34 pm

1 stop21h 59m

$291

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Sat 10/11

4:26 pm-11:30 pm

1 stop7h 04m

Detroit Metropolitan Wayne County

Sat 10/18

8:18 pm-2:32 pm

2 stops42h 14m

$293

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Thu 9/25

5:55 pm-10:10 am

1 stop16h 15m

Detroit Metropolitan Wayne County

Sun 9/28

10:32 am-5:34 pm

2 stops31h 02m

$296

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Thu 10/9

7:45 am-9:30 am

Nonstop1h 45m

Detroit Metropolitan Wayne County

Mon 10/13

7:35 pm-9:13 pm

Nonstop1h 38m

$299

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 17 results
1
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Best time to book a flight from Knoxville to Detroit

Have a flexible travel schedule? Discover the best time to fly to Detroit from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Detroit Metropolitan Wayne County Airport

What is the cheapest month to book a flight from Knoxville to Detroit Metropolitan Wayne County Airport?

Currently, August is the cheapest month in which you can book a flight from Knoxville to Detroit Metropolitan Wayne County Airport (average of $250). Flying from Knoxville to Detroit Metropolitan Wayne County Airport in March is currently the most expensive (average of $305). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to DTW?

Find hourly flight availability from Knoxville to Detroit. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 47% on flights from Knoxville to Detroit Metropolitan Wayne County Airport by exploring options for tickets in the evening.

Reviews of airlines servicing Detroit

Get insights into the airlines that provide service to Detroit. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Detroit. Reviews last updated September 11, 2025.
Read reviews from past customers who have flown Delta and American Airlines from Knoxville to Detroit Metropolitan Wayne County Airport. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Detroit. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Knoxville to Detroit?

    If you wish to fly to Detroit from Knoxville, then you need to book flights from Knoxville McGhee Tyson to Detroit Metropolitan Wayne County. There are 5 flights from McGhee Tyson (TYS) to Detroit Metropolitan Wayne County (DTW) per day to choose from. Flights to Detroit from McGhee Tyson are available from 2 different airlines, which means you should have some options if you want to compare airfare deals. 1h 42m is how long a nonstop flight from Knoxville to Detroit Metropolitan Wayne County typically takes.

  • How long is the flight from Knoxville to Detroit Metropolitan Wayne County Airport?

    A quick flight from Knoxville to Detroit Metropolitan Wayne County Airport can take about 28h 06m. Frontier provides one of the quickest options available for as low as $275. Airlines will cover a distance of 444 mi.

  • What are the cheapest airlines flying from Knoxville to Detroit Metropolitan Wayne County Airport round-trip?

    Cheapflights users have booked flights from Knoxville to Detroit Metropolitan Wayne County Airport round-trip from $318. Another airline that can offer you cheap pricing is Delta. American Airlines is 28% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the most reliable airlines from Knoxville to Detroit Metropolitan Wayne County Airport?

    Consider Air France (85%), Delta (81%) or Endeavor Airlines (81%) when booking your flight. These represent the most reliable airlines when flying from Knoxville to Detroit Metropolitan Wayne County Airport.

  • What are the cheapest flights from Knoxville to Detroit Metropolitan Wayne County Airport?

    Looking at all options, your cheapest flight can be booked for $138. While the most popular route (Knoxville McGhee Tyson - Detroit Metropolitan Wayne County) can be booked for $229 on average, our data indicates $429 when flying from Knoxville to Detroit Metropolitan Wayne County Airport.

  • Can I find deals for flights from Knoxville to Detroit that include hotel bookings?

    Yes. In addition to deals on Knoxville to Detroit flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Detroit?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Detroit.

  • Can I find deals for business class flights from Knoxville to Detroit?

    Yes. Cheapflights offers flight deals from Knoxville to Detroit by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Detroit Metropolitan Wayne County Airport?

    Currently, August is the cheapest month in which you can book a flight from Knoxville to Detroit Metropolitan Wayne County Airport (average of $250). Flying from Knoxville to Detroit Metropolitan Wayne County Airport in March is currently the most expensive (average of $305). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Detroit Metropolitan Wayne County Airport?

Book flights to Detroit Metropolitan Wayne County Airport if you plan to visit one of these locations
Sterling Heights
Dearborn
Troy
Warren
Southfield
Novi
Clarkston
Allen Park
Utica
Plymouth
Monroe
Wixom
Brighton
Livonia
Roseville
Fremont
Port Huron
Auburn Hills
Madison Heights
Southgate

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Knoxville to Detroit

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Knoxville to Detroit

Discover the top 2 airlines that operate flights from Knoxville to Detroit. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$318Average$368FlexibilityNo cancel feeOn-time71%
DeltaCheapest$319Average$460FlexibilityNo cancel feeOn-timeN/A

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