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$85+ Cheap flights from Knoxville to Detroit Metropolitan Wayne County Airport (TYS - DTW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/13. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — DTW
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Find flight deals from Knoxville to Detroit

Cheapest flights from Knoxville to Detroit
Explore the most affordable flight options available from Knoxville to Detroit. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/114:52 pmTYS - DTW
1 stop23h 27mMultiple Airlines
Mon 1/127:00 amDTW - TYS
1 stop10h 28mMultiple Airlines
Deal found 10/29$223
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/139:54 amTYS - DTW
2 stops13h 04mMultiple Airlines
Sun 11/1612:24 pmDTW - TYS
1 stop25h 33mMultiple Airlines
Deal found 10/30$238
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/195:07 pmTYS - DTW
2 stops21h 00mMultiple Airlines
Fri 11/2110:27 amDTW - TYS
1 stop11h 08mMultiple Airlines
Deal found 10/30$272
This Mytrip deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/259:53 amTYS - DTW
1 stop14h 01mMultiple Airlines
Mon 12/17:11 amDTW - TYS
2 stops8h 38mMultiple Airlines
Deal found 10/30$290
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/202:53 pmTYS - DTW
1 stop10h 26mMultiple Airlines
Mon 12/2912:29 pmDTW - TYS
1 stop10h 52mMultiple Airlines
Deal found 10/29$291
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1112:50 pmTYS - DTW
Nonstop1h 46mDelta
Mon 1/1210:20 amDTW - TYS
Nonstop1h 53mDelta
Deal found 10/29$299

Cheap flight deals from Knoxville to Detroit

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Detroit (DTW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 30, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$203
(Mytrip)

One-way from

$85
(Mytrip)

Popular in

January

Cheapest in

December

Average price

$469

Good round-trip deal

$356 or less

Good one-way deal

$283 or less
Provider with most accurate pricing for Knoxville McGhee Tyson-Detroit Metropolitan Wayne County flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Detroit Metropolitan Wayne County flights.
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From Knoxville McGhee Tyson to Detroit Metropolitan Wayne County
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One-way flight from Knoxville McGhee Tyson to Detroit Metropolitan Wayne County
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High demand for flights, 0% potential price rise
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Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Price to beat on a round-trip flight from Knoxville McGhee Tyson to Detroit Metropolitan Wayne County.
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Price to beat on a one-way flight from Knoxville McGhee Tyson to Detroit Metropolitan Wayne County.
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Detroit that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Knoxville to Detroit Metropolitan Wayne County Airport that are best for you.

Fly from

Knoxville

Fly to

Detroit

Route

Depart

Return

Price

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Thu 12/11

4:52 pm-4:19 pm

1 stop23h 27m

Detroit Metropolitan Wayne County

Mon 1/12

7:00 am-5:28 pm

1 stop10h 28m

$223

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Thu 11/13

9:54 am-10:58 pm

2 stops13h 04m

Detroit Metropolitan Wayne County

Sun 11/16

9:39 pm-1:57 pm

2 stops16h 18m

$270

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Wed 11/26

7:00 am-2:38 pm

2 stops31h 38m

Detroit Metropolitan Wayne County

Wed 12/3

6:46 pm-11:31 am

1 stop16h 45m

$270

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Thu 12/11

12:50 pm-2:36 pm

Nonstop1h 46m

Detroit Metropolitan Wayne County

Mon 1/12

10:20 am-12:13 pm

Nonstop1h 53m

$299

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Tue 11/25

9:53 am-9:44 pm

1 stop11h 51m

Detroit Metropolitan Wayne County

Mon 12/1

7:11 am-3:49 pm

2 stops8h 38m

$300

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Sat 12/20

5:23 pm-1:24 pm

1 stop20h 01m

Detroit Metropolitan Wayne County

Mon 12/29

3:39 pm-9:44 pm

2 stops30h 05m

$306

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Sat 12/13

7:30 am-9:20 am

Nonstop1h 50m

Detroit Metropolitan Wayne County

Sun 1/18

7:00 pm-8:47 pm

Nonstop1h 47m

$339

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Mon 1/26

7:15 am-5:18 pm

1 stop10h 03m

$104

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Mon 12/1

12:50 pm-11:46 pm

2 stops34h 56m

$130

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Tue 11/25

9:53 am-9:44 pm

1 stop11h 51m

$130

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 15 results
1
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Compare providers for flights from Knoxville to Detroit

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Detroit in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Detroit Metropolitan Wayne County Airport flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on Knoxville-Detroit Metropolitan Wayne County Airport flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from Knoxville-Detroit Metropolitan Wayne County Airport flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Detroit Metropolitan Wayne County Airport flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Detroit Metropolitan Wayne County Airport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Detroit

Have a flexible travel schedule? Discover the best time to fly to Detroit from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Detroit Metropolitan Wayne County Airport

What is the cheapest month to book a flight from Knoxville to Detroit Metropolitan Wayne County Airport?

Currently, March is the cheapest month in which you can book a flight from Knoxville to Detroit Metropolitan Wayne County Airport (average of $205). Flying from Knoxville to Detroit Metropolitan Wayne County Airport in April is currently the most expensive (average of $271). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to DTW?

Find hourly flight availability from Knoxville to Detroit. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 38% on flights from Knoxville to Detroit Metropolitan Wayne County Airport by exploring options for tickets in the evening.

Reviews of airlines servicing Detroit

Get insights into the airlines that provide service to Detroit. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Detroit. Reviews last updated October 30, 2025.
Read reviews from past customers who have flown Delta and American Airlines from Knoxville to Detroit Metropolitan Wayne County Airport. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,998 reviews

Overall

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,998 reviews
Delta
7.9
Good
7,998 reviews

Overall

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,035 reviews
Delta
7.9
Good
7,998 reviews

Overall

7.9

Boarding

8.2

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Detroit. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Knoxville to Detroit?

    If you wish to fly to Detroit from Knoxville, then you need to book flights from Knoxville McGhee Tyson to Detroit Metropolitan Wayne County. There are 4 flights from McGhee Tyson (TYS) to Detroit Metropolitan Wayne County (DTW) per day to choose from. Flights to Detroit from McGhee Tyson are available from 2 different airlines, which means you should have some options if you want to compare airfare deals. 1h 43m is how long a nonstop flight from Knoxville to Detroit Metropolitan Wayne County typically takes.

  • What are the cheapest airlines flying from Knoxville to Detroit Metropolitan Wayne County Airport round-trip?

    Cheapflights users have booked flights from Knoxville to Detroit Metropolitan Wayne County Airport round-trip from $318. Another airline that can offer you cheap pricing is Delta. American Airlines is 29% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the most reliable airlines from Knoxville to Detroit Metropolitan Wayne County Airport?

    Consider KLM (93%), Virgin Atlantic (93%) or Delta (89%) when booking your flight. These represent the most reliable airlines when flying from Knoxville to Detroit Metropolitan Wayne County Airport.

  • What are the cheapest flights from Knoxville to Detroit Metropolitan Wayne County Airport?

    Looking at all options, your cheapest flight can be booked for $155. While the most popular route (Knoxville McGhee Tyson - Detroit Metropolitan Wayne County) can be booked for $203 on average, our data indicates $475 when flying from Knoxville to Detroit Metropolitan Wayne County Airport.

  • Can I find deals for flights from Knoxville to Detroit that include hotel bookings?

    Yes. In addition to deals on Knoxville to Detroit flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Detroit?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Detroit.

  • Can I find deals for business class flights from Knoxville to Detroit?

    Yes. Cheapflights offers flight deals from Knoxville to Detroit by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Detroit Metropolitan Wayne County Airport?

    Currently, March is the cheapest month in which you can book a flight from Knoxville to Detroit Metropolitan Wayne County Airport (average of $205). Flying from Knoxville to Detroit Metropolitan Wayne County Airport in April is currently the most expensive (average of $271). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Detroit Metropolitan Wayne County Airport?

Book flights to Detroit Metropolitan Wayne County Airport if you plan to visit one of these locations
Sterling Heights
Dearborn
Warren
Southfield
Troy
Novi
Clarkston
Allen Park
Utica
Romulus
Auburn Hills
Plymouth
Monroe
Wixom
Ypsilanti
Brighton
Livonia
Roseville
Fremont
Port Huron

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Alternative routes for Knoxville to Detroit

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Knoxville to Detroit

Discover the top 2 airlines that operate flights from Knoxville to Detroit. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$318Average$368FlexibilityNo cancel feeOn-time71%
DeltaCheapest$319Average$425FlexibilityNo cancel feeOn-timeN/A

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