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$114+ Cheap flights from Knoxville to Detroit Metropolitan Wayne County Airport (TYS - DTW)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/12. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — DTW
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Knoxville to Detroit

Cheapest flights from Knoxville to Detroit
Explore the most affordable flight options available from Knoxville to Detroit. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/307:39 amTYS - DTW
Nonstop1h 50mDelta
Fri 1/26:52 pmDTW - TYS
Nonstop1h 40mDelta
Deal found 12/10$359
This Delta deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/267:39 amTYS - DTW
Nonstop1h 50mDelta
Fri 1/27:00 amDTW - TYS
1 stop4h 58mDelta
Deal found 12/11$379
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/265:08 pmTYS - DTW
1 stop6h 51mAmerican Airlines
Fri 1/211:56 amDTW - TYS
1 stop4h 48mAmerican Airlines
Deal found 12/11$389
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/265:35 pmTYS - DTW
1 stop4h 55mUnited Airlines
Tue 12/302:30 pmDTW - TYS
1 stop5h 21mUnited Airlines
Deal found 12/11$419
This Delta deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/137:30 amTYS - DTW
Nonstop1h 50mDelta
Sun 1/186:15 amDTW - TYS
1 stop4h 00mDelta
Deal found 12/11$429
This Kiwi.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1012:53 pmTYS - DTW
1 stop21h 15mMultiple Airlines
Wed 12/175:50 amDTW - TYS
2 stops26h 28mMultiple Airlines
Deal found 12/9$431
This Delta deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/234:31 pmTYS - DTW
1 stop5h 57mDelta
Fri 12/266:52 pmDTW - TYS
Nonstop1h 40mDelta
Deal found 12/10$439
This Kiwi.com deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/156:30 amTYS - DTW
2 stops25h 37mMultiple Airlines
Wed 12/176:15 amDTW - TYS
1 stop11h 57mMultiple Airlines
Deal found 12/11$441
This Kiwi.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2411:08 amTYS - DTW
1 stop12h 51mMultiple Airlines
Sun 12/287:20 pmDTW - TYS
2 stops52h 12mMultiple Airlines
Deal found 12/9$447
This Mytrip deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/129:23 amTYS - DTW
1 stop14h 56mMultiple Airlines
Sun 12/147:42 pmDTW - TYS
1 stop14h 50mMultiple Airlines
Deal found 12/11$457

Find flight deals from Knoxville to Detroit

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Detroit (DTW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$213
(Kiwi.com)

One-way from

$114
(Kiwi.com)

Popular in

November

Cheapest in

April

Average price

$499

Good round-trip deal

$439 or less

Good one-way deal

$278 or less
Provider with most accurate pricing for Knoxville McGhee Tyson-Detroit Metropolitan Wayne County flight deals.
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Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Detroit Metropolitan Wayne County flights.
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From Knoxville McGhee Tyson to Detroit Metropolitan Wayne County
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One-way flight from Knoxville McGhee Tyson to Detroit Metropolitan Wayne County
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Highest demand for flights based on searches. 8% potential increase in price ($41 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Price to beat on a round-trip flight from Knoxville McGhee Tyson to Detroit Metropolitan Wayne County.
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Price to beat on a one-way flight from Knoxville McGhee Tyson to Detroit Metropolitan Wayne County.
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Detroit that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Knoxville to Detroit Metropolitan Wayne County Airport that are best for you.

Fly from

Knoxville

Fly to

Detroit

Route

Depart

Return

Price

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Wed 1/14

4:47 pm-5:04 pm

1 stop24h 17m

Detroit Metropolitan Wayne County

Tue 2/3

6:36 pm-3:57 pm

1 stop21h 21m

$227

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Thu 1/8

1:39 pm-10:20 am

2 stops44h 41m

Detroit Metropolitan Wayne County

Thu 1/15

1:18 pm-5:28 pm

1 stop28h 10m

$245

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Fri 1/9

12:55 pm-11:41 pm

1 stop10h 46m

Detroit Metropolitan Wayne County

Sun 1/11

5:15 pm-5:28 pm

1 stop24h 13m

$262

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Tue 2/17

4:04 pm-11:57 pm

1 stop7h 53m

Detroit Metropolitan Wayne County

Thu 2/19

10:59 pm-12:00 pm

1 stop13h 01m

$285

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Fri 4/3

7:40 am-9:20 am

Nonstop1h 40m

Detroit Metropolitan Wayne County

Sat 4/4

6:15 pm-11:51 pm

1 stop5h 36m

$309

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Thu 1/8

1:00 pm-2:53 pm

Nonstop1h 53m

Detroit Metropolitan Wayne County

Thu 1/15

10:00 am-4:19 pm

1 stop6h 19m

$329

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Tue 12/30

7:39 am-9:29 am

Nonstop1h 50m

Detroit Metropolitan Wayne County

Fri 1/2

6:52 pm-8:32 pm

Nonstop1h 40m

$359

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Mon 2/9

7:15 am-12:19 am

1 stop17h 04m

$115

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Sun 1/11

1:39 pm-2:30 pm

2 stops24h 51m

$116

KnoxvilleDetroit

TYS - DTW

TYSDTW

Knoxville McGhee Tyson

Tue 1/6

7:22 pm-1:19 am

2 stops29h 57m

$132

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/9

Showing 1-10 of 16 results
1
2

Compare providers for flights from Knoxville to Detroit

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Detroit in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Detroit Metropolitan Wayne County Airport flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on Knoxville-Detroit Metropolitan Wayne County Airport flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from Knoxville-Detroit Metropolitan Wayne County Airport flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Detroit Metropolitan Wayne County Airport flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Detroit Metropolitan Wayne County Airport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Detroit

Have a flexible travel schedule? Discover the best time to fly to Detroit from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Detroit Metropolitan Wayne County Airport

What is the cheapest month to book a flight from Knoxville to Detroit Metropolitan Wayne County Airport?

Currently, March is the cheapest month in which you can book a flight from Knoxville to Detroit Metropolitan Wayne County Airport (average of $205). Flying from Knoxville to Detroit Metropolitan Wayne County Airport in November is currently the most expensive (average of $358). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to DTW?

Find hourly flight availability from Knoxville to Detroit. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 34% on flights from Knoxville to Detroit Metropolitan Wayne County Airport by exploring options for tickets in the evening.

Reviews of airlines servicing Detroit

Get insights into the airlines that provide service to Detroit. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Detroit. Reviews last updated December 12, 2025.
Read reviews from past customers who have flown Delta and American Airlines from Knoxville to Detroit Metropolitan Wayne County Airport. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Entertainment

7.9

Overall

7.9

Comfort

7.9

Boarding

8.1

Crew

8.5

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Entertainment

7.9

Overall

7.9

Comfort

7.9

Boarding

8.1

Crew

8.5

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,050 reviews
Delta
7.9
Good
8,007 reviews

Entertainment

7.9

Overall

7.9

Comfort

7.9

Boarding

8.1

Crew

8.5

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Detroit. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Knoxville to Detroit?

    If you wish to fly to Detroit from Knoxville, then you need to book flights from Knoxville McGhee Tyson to Detroit Metropolitan Wayne County. There are 6 flights from McGhee Tyson (TYS) to Detroit Metropolitan Wayne County (DTW) per day to choose from. Flights to Detroit from McGhee Tyson are available from 2 different airlines, which means you should have some options if you want to compare airfare deals. 1h 46m is how long a nonstop flight from Knoxville to Detroit Metropolitan Wayne County typically takes.

  • How long is the flight from Knoxville to Detroit Metropolitan Wayne County Airport?

    A quick flight from Knoxville to Detroit Metropolitan Wayne County Airport can take about 1h 40m. Delta provides one of the quickest options available for as low as $309. Airlines will cover a distance of 444 mi. Most flights are nonstop.

  • What are the cheapest airlines flying from Knoxville to Detroit Metropolitan Wayne County Airport round-trip?

    Cheapflights users have booked flights from Knoxville to Detroit Metropolitan Wayne County Airport round-trip from $158. Another airline that can offer you cheap pricing is Delta. American Airlines is 65% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Knoxville to Detroit Metropolitan Wayne County Airport one-way?

    For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $138. Users have also found prices from $239 and $248 on United Airlines and Delta, respectively.

  • What are the most reliable airlines from Knoxville to Detroit Metropolitan Wayne County Airport?

    Consider WestJet (93%), Korean Air (87%) or Delta (85%) when booking your flight. These represent the most reliable airlines when flying from Knoxville to Detroit Metropolitan Wayne County Airport.

  • What are the cheapest flights from Knoxville to Detroit Metropolitan Wayne County Airport?

    Looking at all options, your cheapest flight can be booked for $213. While the most popular route (Knoxville McGhee Tyson - Detroit Metropolitan Wayne County) can be booked for $213 on average, our data indicates $487 when flying from Knoxville to Detroit Metropolitan Wayne County Airport.

  • Can I find deals for flights from Knoxville to Detroit that include hotel bookings?

    Yes. In addition to deals on Knoxville to Detroit flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Detroit?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Detroit.

  • Can I find deals for business class flights from Knoxville to Detroit?

    Yes. Cheapflights offers flight deals from Knoxville to Detroit by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Detroit Metropolitan Wayne County Airport?

    Currently, March is the cheapest month in which you can book a flight from Knoxville to Detroit Metropolitan Wayne County Airport (average of $205). Flying from Knoxville to Detroit Metropolitan Wayne County Airport in November is currently the most expensive (average of $358). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Detroit Metropolitan Wayne County Airport?

Book flights to Detroit Metropolitan Wayne County Airport if you plan to visit one of these locations
Sterling Heights
Dearborn
Southfield
Warren
Troy
Auburn Hills
Novi
Allen Park
Clarkston
Utica
Rochester Hills
Roseville
Romulus
Monroe
Wixom
Ypsilanti
Brighton
Livonia
Plymouth
Fremont

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Alternative routes for Knoxville to Detroit

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Knoxville to Detroit

Discover the top 2 airlines that operate flights from Knoxville to Detroit. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$158Average$398FlexibilityNo cancel feeOn-time71%
DeltaCheapest$299Average$430FlexibilityNo cancel feeOn-timeN/A

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