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Des Moines

$344+ Cheap flights from Manchester, NH to Des Moines (MHT - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
MHT — DSM
Nov 15 — Nov 221
Sat 11/15
Sat 11/22
1 adult, Economy
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Cheap flight deals from Manchester to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MHT) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 16, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$407
(American Airlines)

One-way from

$344
(United Airlines)

Popular in

March

Cheapest in

May

Average price

$386
Provider with most accurate pricing for Manchester-Des Moines flight deals.
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Provider most trusted by Cheapflights users for Manchester-Des Moines flights.
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From Manchester to Des Moines
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One-way flight from Manchester to Des Moines
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Highest demand for flights based on searches. 15% potential increase in price ($86 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($25 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Manchester to Des Moines

Cheapest flights from Manchester to Des Moines
Explore the most affordable flight options available from Manchester to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 16, 2025.

This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/76:00 amMHT - DSM
1 stop7h 24mAmerican Airlines
Mon 11/105:04 pmDSM - MHT
1 stop5h 44mAmerican Airlines
Deal found 10/15$437
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/312:27 pmMHT - DSM
2 stops10h 15mUnited Airlines
Tue 11/41:35 pmDSM - MHT
2 stops9h 09mUnited Airlines
Deal found 10/16$454
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/287:07 amMHT - DSM
1 stop8h 14mAmerican Airlines
Fri 10/316:00 amDSM - MHT
1 stop4h 56mAmerican Airlines
Deal found 10/15$509
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/72:27 pmMHT - DSM
2 stops10h 17mUnited Airlines
Mon 11/103:15 pmDSM - MHT
2 stops7h 29mUnited Airlines
Deal found 10/15$513
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/289:30 amMHT - DSM
2 stops12h 15mUnited Airlines
Fri 10/313:15 pmDSM - MHT
2 stops7h 29mUnited Airlines
Deal found 10/15$519
This Southwest deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/165:00 amMHT - DSM
2 stops13h 35mSouthwest
Mon 12/16:50 pmDSM - MHT
2 stops12h 15mSouthwest
Deal found 10/15$616
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/166:00 amMHT - DSM
2 stops10h 32mAmerican Airlines
Mon 12/12:15 pmDSM - MHT
1 stop7h 37mAmerican Airlines
Deal found 10/15$690

Cheapflights Fare Finder

 
Customize your flight search to find flights from Manchester to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
Use the filters below to find and compare flights from Manchester to Des Moines that are best for you.

Fly from

Manchester

Fly to

Des Moines

Route

Depart

Return

Price

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Tue 3/3

2:33 pm-11:43 pm

2 stops10h 10m

Des Moines

Wed 3/4

8:00 am-6:53 pm

2 stops9h 53m

$417

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Fri 10/31

2:27 pm-11:42 pm

2 stops10h 15m

Des Moines

Tue 11/4

1:35 pm-11:44 pm

2 stops9h 09m

$454

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Fri 11/7

4:05 pm-11:30 pm

1 stop8h 25m

Des Moines

Mon 11/10

6:00 am-11:39 am

1 stop4h 39m

$503

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Sun 11/16

5:43 am-1:31 pm

1 stop8h 48m

Des Moines

Mon 12/1

2:15 pm-10:52 pm

1 stop7h 37m

$503

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Tue 10/28

7:07 am-2:21 pm

1 stop8h 14m

Des Moines

Fri 10/31

6:00 am-11:56 am

1 stop4h 56m

$509

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Fri 11/7

2:27 pm-11:44 pm

2 stops10h 17m

Des Moines

Mon 11/10

3:15 pm-11:44 pm

2 stops7h 29m

$513

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Tue 10/28

9:30 am-8:45 pm

2 stops12h 15m

Des Moines

Fri 10/31

3:15 pm-11:44 pm

2 stops7h 29m

$519

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Tue 3/3

5:39 am-12:30 pm

1 stop7h 51m

Des Moines

Wed 3/4

5:59 am-11:30 pm

2 stops16h 31m

$534

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Tue 10/21

9:40 am-5:24 pm

2 stops8h 44m

$344

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/15

Compare providers for flights from Manchester to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Manchester to Des Moines in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Manchester, New Hampshire-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Manchester, New Hampshire-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Manchester, New Hampshire-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Manchester, New Hampshire-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Manchester, New Hampshire-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Manchester to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Manchester with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Des Moines

What is the cheapest month to book a flight from Manchester, New Hampshire to Des Moines?

Currently, September is the cheapest month in which you can book a flight from Manchester, New Hampshire to Des Moines (average of $108). Flying from Manchester, New Hampshire to Des Moines in January is currently the most expensive (average of $374). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MHT to DSM?

Find hourly flight availability from Manchester to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 16, 2025.

One of the essential ways to save on airfare from Manchester, New Hampshire to Des Moines is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight at noon could potentially save you up to 36% on airfare.

How much does it cost to fly round-trip from Manchester, New Hampshire to Des Moines?

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated October 16, 2025.
Get a feel of what it's like to fly with American Airlines from Manchester to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,043 reviews

Entertainment

6.9

Food

6.4

Boarding

7.5

Crew

8.0

Comfort

7.2

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac
American Airlines
7.2
Good
11,043 reviews
American Airlines
7.2
Good
11,043 reviews

Entertainment

6.9

Food

6.4

Boarding

7.5

Crew

8.0

Comfort

7.2

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Jeremy,Sep 2025

SAN - PHL

Terrible. Bad customer service and unacceptable delay on the tarmac

Related info for your journey

Find useful and relevant information for your journey from Manchester to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Manchester, New Hampshire to Des Moines?

    United Airlines and American Airlines can get you from Manchester, New Hampshire to Des Moines in just under 8h 25m. Your travel time can differ by up to 1h 45m. Manchester, New Hampshire and Des Moines are separated by a distance of 1137 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Manchester, New Hampshire to Des Moines round-trip?

    Cheapflights users have booked flights from Manchester, New Hampshire to Des Moines round-trip from $316. American Airlines is currently priced 34% below the average price you’ll pay for this route.

  • Can I find deals for flights from Manchester to Des Moines that include hotel bookings?

    Yes. In addition to deals on Manchester to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Des Moines.

  • Can I find deals for business class flights from Manchester to Des Moines?

    Yes. Cheapflights offers flight deals from Manchester to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester, New Hampshire to Des Moines?

    Currently, September is the cheapest month in which you can book a flight from Manchester, New Hampshire to Des Moines (average of $108). Flying from Manchester, New Hampshire to Des Moines in January is currently the most expensive (average of $374). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Johnston
Altoona
Boone
Ames
West Des Moines
Ankeny

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Top airline flying from Manchester to Des Moines

Discover the top airline that operate flights from Manchester to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$316Average$466FlexibilityNo cancel feeOn-time71%

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