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Des Moines

$148+ Cheap flights from Manchester, NH to Des Moines (MHT - DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/29. Fares are subject to change and may not be available on all flights or dates of travel.
MHT — DSM
Aug 19 — Aug 261
Tue 8/19
Tue 8/26
1 adult, Economy
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Cheap flight deals from Manchester to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MHT) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 14, 2025.

Round-trip from

$295
(American Airlines)

One-way from

$148
(American Airlines)

Popular in

March

Cheapest in

May

Average price

$391
From Manchester to Des Moines
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One-way flight from Manchester to Des Moines
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Highest demand for flights based on searches. 15% potential increase in price ($85 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($25 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Manchester to Des Moines

Cheapest flights from Manchester to Des Moines
Explore the most affordable flight options available from Manchester to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/185:48 pmMHT - DSM
1 stop6h 40mAmerican Airlines
Mon 9/226:09 pmDSM - MHT
1 stop4h 50mAmerican Airlines
Deal found 8/14$295
This Southwest deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1812:45 pmMHT - DSM
2 stops11h 05mSouthwest
Mon 9/225:30 pmDSM - MHT
2 stops13h 40mSouthwest
Deal found 8/13$311
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/75:20 pmMHT - DSM
1 stop5h 49mAmerican Airlines
Mon 11/103:18 pmDSM - MHT
1 stop7h 30mAmerican Airlines
Deal found 8/13$357
This Southwest deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/161:40 pmMHT - DSM
2 stops10h 50mSouthwest
Sat 10/187:25 amDSM - MHT
2 stops13h 30mSouthwest
Deal found 8/13$473
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/248:00 amMHT - DSM
1 stop6h 05mAmerican Airlines
Wed 9/243:50 pmDSM - MHT
1 stop7h 19mAmerican Airlines
Deal found 8/13$519
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/267:04 amMHT - DSM
1 stop6h 35mAmerican Airlines
Wed 8/276:28 amDSM - MHT
1 stop4h 46mAmerican Airlines
Deal found 8/13$595
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/185:38 pmMHT - DSM
1 stop6h 46mAmerican Airlines
Thu 9/47:55 amDSM - MHT
1 stop6h 53mAmerican Airlines
Deal found 8/13$607
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/79:30 amMHT - DSM
2 stops12h 15mUnited Airlines
Mon 11/106:50 pmDSM - MHT
2 stops27h 54mUnited Airlines
Deal found 8/13$608
This Southwest deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/182:50 pmMHT - DSM
2 stops9h 00mSouthwest
Thu 9/46:00 amDSM - MHT
2 stops12h 55mSouthwest
Deal found 8/13$623
This Southwest deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/262:25 pmMHT - DSM
2 stops8h 55mSouthwest
Wed 8/276:30 amDSM - MHT
2 stops9h 15mSouthwest
Deal found 8/13$631
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/217:04 amMHT - DSM
1 stop6h 35mAmerican Airlines
Thu 8/283:21 pmDSM - MHT
1 stop7h 38mAmerican Airlines
Deal found 8/14$637

Cheapflights Fare Finder

 
Customize your flight search to find flights from Manchester to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
Use the filters below to find and compare flights from Manchester to Des Moines that are best for you.

Fly from

Manchester

Fly to

Des Moines

Route

Depart

Return

Price

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Thu 9/18

5:48 pm-11:28 pm

1 stop6h 40m

Des Moines

Mon 9/22

6:09 pm-11:59 pm

1 stop4h 50m

$295

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Thu 9/18

12:45 pm-10:50 pm

2 stops11h 05m

Des Moines

Mon 9/22

5:30 pm-8:10 am

2 stops13h 40m

$311

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Thu 10/16

7:34 pm-11:23 pm

1 stop4h 49m

Des Moines

Sat 10/18

6:07 pm-11:56 pm

1 stop4h 49m

$311

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Fri 11/7

5:20 pm-10:09 pm

1 stop5h 49m

Des Moines

Mon 11/10

3:18 pm-11:48 pm

1 stop7h 30m

$357

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Thu 10/16

1:40 pm-11:30 pm

2 stops10h 50m

Des Moines

Sat 10/18

7:25 am-9:55 pm

2 stops13h 30m

$473

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Wed 9/24

8:00 am-1:05 pm

1 stop6h 05m

Des Moines

Wed 9/24

3:50 pm-12:09 am

1 stop7h 19m

$519

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Tue 8/26

7:04 am-12:39 pm

1 stop6h 35m

Des Moines

Wed 8/27

6:28 am-12:14 pm

1 stop4h 46m

$595

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Fri 11/7

9:30 am-8:45 pm

2 stops12h 15m

Des Moines

Mon 11/10

6:50 pm-11:44 pm

2 stops27h 54m

$608

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Mon 9/29

3:22 pm-11:06 pm

1 stop8h 44m

$148

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Mon 9/29

9:40 am-8:18 pm

2 stops35h 38m

$482

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/13

Best time to book a flight from Manchester to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Manchester with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Des Moines

What is the cheapest month to book a flight from Manchester, New Hampshire to Des Moines?

Currently, August is the cheapest month in which you can book a flight from Manchester, New Hampshire to Des Moines (average of $336). Flying from Manchester, New Hampshire to Des Moines in June is currently the most expensive (average of $401). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MHT to DSM?

Find hourly flight availability from Manchester to Des Moines. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 14, 2025.

One of the essential ways to save on airfare from Manchester, New Hampshire to Des Moines is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight at noon could potentially save you up to 14% on airfare.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated August 14, 2025.
Get a feel of what it's like to fly with American Airlines from Manchester to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Boarding

7.5

Entertainment

6.9

Comfort

7.2

Overall

7.2

Crew

8.0

Food

6.5

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Boarding

7.5

Entertainment

6.9

Comfort

7.2

Overall

7.2

Crew

8.0

Food

6.5

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.

Related info for your journey

Find useful and relevant information for your journey from Manchester to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What is the cheapest airline to fly from Manchester, New Hampshire to Des Moines round-trip?

    Cheapflights users have booked flights from Manchester, New Hampshire to Des Moines round-trip from $316. American Airlines is currently priced 34% below the average price you’ll pay for this route.

  • Can I find deals for flights from Manchester to Des Moines that include hotel bookings?

    Yes. In addition to deals on Manchester to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Des Moines.

  • Can I find deals for business class flights from Manchester to Des Moines?

    Yes. Cheapflights offers flight deals from Manchester to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester, New Hampshire to Des Moines?

    Currently, August is the cheapest month in which you can book a flight from Manchester, New Hampshire to Des Moines (average of $336). Flying from Manchester, New Hampshire to Des Moines in June is currently the most expensive (average of $401). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Ames
Johnston
Boone
West Des Moines
Ankeny

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Top airline flying from Manchester to Des Moines

Discover the top airline that operate flights from Manchester to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$316Average$465FlexibilityNo cancel feeOn-time71%

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