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Des Moines

$357+ Cheap flights from Manchester, NH to Des Moines (MHT - DSM)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/28. Fares are subject to change and may not be available on all flights or dates of travel.
MHT — DSM
Apr 16 — Apr 231
Thu 4/16
Thu 4/23
1 adult, Economy
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Cheap flight deals from Manchester to Des Moines

Cheapest flights from Manchester to Des Moines
Explore the most affordable flight options available from Manchester to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 17, 2026.

This Southwest deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:30 am
MHT
-
DSM
1 stop4h 55m
Southwest
Tue 5/53:15 pm
DSM
-
MHT
1 stop4h 50m
Southwest
Deal found 3/14$357
This American Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/115:41 pm
MHT
-
DSM
1 stop7h 08m
American Airlines
Sat 4/187:05 am
DSM
-
MHT
1 stop7h 56m
American Airlines
Deal found 3/14$381
This Southwest deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/117:40 am
MHT
-
DSM
1 stop4h 50m
Southwest
Sat 4/185:35 am
DSM
-
MHT
2 stops7h 35m
Southwest
Deal found 3/14$386
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/266:46 am
MHT
-
DSM
1 stop8h 00m
American Airlines
Wed 4/295:44 am
DSM
-
MHT
1 stop4h 58m
American Airlines
Deal found 3/16$392
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/267:00 pm
MHT
-
DSM
1 stop5h 20m
Southwest
Wed 4/296:30 pm
DSM
-
MHT
2 stops13h 00m
Southwest
Deal found 3/16$403
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/912:12 pm
MHT
-
DSM
1 stop8h 21m
American Airlines
Mon 4/135:01 pm
DSM
-
MHT
1 stop4h 50m
American Airlines
Deal found 3/17$405
This United Airlines deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/112:30 pm
MHT
-
DSM
2 stops10h 12m
United Airlines
Sat 4/188:04 am
DSM
-
MHT
2 stops9h 52m
United Airlines
Deal found 3/14$411
This Southwest deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/297:25 am
MHT
-
DSM
1 stop5h 20m
Southwest
Sun 5/315:20 am
DSM
-
MHT
1 stop4h 20m
Southwest
Deal found 3/12$427
This American Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:02 pm
MHT
-
DSM
1 stop6h 57m
American Airlines
Mon 7/131:41 pm
DSM
-
MHT
1 stop8h 10m
American Airlines
Deal found 3/12$443

Find flight deals from Manchester to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Manchester (MHT) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 17, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$357
(Southwest)

Popular in

January

Cheapest in

May

Average price

$750
Provider with most accurate pricing for Manchester-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Manchester-Des Moines flights.
Search Deals
From Manchester to Des Moines
Search Deals
Highest demand for flights based on searches. 44% potential increase in price ($498 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 14% potential price decrease ($79 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Manchester to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
Use the filters below to find and compare flights from Manchester to Des Moines that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Sat 4/11

7:40 am-11:30 am

1 stop4h 50m

Des Moines

Sat 4/18

5:35 am-2:10 pm

2 stops7h 35m

$386

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Fri 5/29

7:25 am-11:45 am

1 stop5h 20m

Des Moines

Sun 5/31

5:20 am-10:40 am

1 stop4h 20m

$427
Quickest round-trip

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Fri 5/1

7:10 pm-11:05 pm

1 stop4h 55m

Des Moines

Sun 5/3

5:20 am-10:40 am

1 stop4h 20m

$427

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Sun 4/5

7:20 am-11:30 am

1 stop5h 10m

Des Moines

Fri 4/10

4:20 pm-9:55 pm

1 stop4h 35m

$447

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Sun 4/5

4:00 pm-10:10 pm

1 stop7h 10m

Des Moines

Fri 4/10

11:09 am-5:11 pm

1 stop5h 02m

$477

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Sat 4/11

2:30 pm-11:42 pm

2 stops10h 12m

Des Moines

Wed 4/15

8:04 am-6:56 pm

2 stops9h 52m

$485

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Sun 3/29

7:20 am-11:30 am

1 stop5h 10m

Des Moines

Thu 4/2

4:20 pm-10:05 pm

1 stop4h 45m

$547
Cheapest one-way

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Sun 3/22

11:23 am-7:16 pm

3 stops32h 53m

$581
Quickest one-way

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Sun 3/22

4:00 pm-9:51 pm

1 stop6h 51m

$603

ManchesterDes Moines

MHT - DSM

MHTDSM

Manchester

Sun 3/22

7:28 pm-8:27 pm

2 stops25h 59m

$894

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/16

Sorted by cheapest first

Compare providers for flights from Manchester to Des Moines

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Manchester to Des Moines in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Manchester, New Hampshire-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Manchester, New Hampshire-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Manchester, New Hampshire-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Manchester, New Hampshire-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Manchester, New Hampshire-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Manchester to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Manchester with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Manchester to Des Moines

What is the cheapest month to book a flight from Manchester, New Hampshire to Des Moines?

Currently, December is the cheapest month in which you can book a flight from Manchester, New Hampshire to Des Moines (average of $92). Flying from Manchester, New Hampshire to Des Moines in March is currently the most expensive (average of $333). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated March 17, 2026.
Get a feel of what it's like to fly with American Airlines from Manchester to Des Moines by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,468 reviews

Crew

7.9

Entertainment

6.9

Boarding

7.5

Comfort

7.2

Overall

7.1

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes
American Airlines
7.1
Good
11,468 reviews
American Airlines
7.1
Good
11,468 reviews

Crew

7.9

Entertainment

6.9

Boarding

7.5

Comfort

7.2

Overall

7.1

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes

Related info for your journey

Find useful and relevant information for your journey from Manchester to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Manchester, New Hampshire to Des Moines?

    Southwest can get you from Manchester, New Hampshire to Des Moines in just under 4h 50m. Your travel time can differ by up to . Manchester, New Hampshire and Des Moines are separated by a distance of 1137 mi.

  • What is the cheapest airline to fly from Manchester, New Hampshire to Des Moines round-trip?

    Cheapflights users have booked flights from Manchester, New Hampshire to Des Moines round-trip from $316. American Airlines is currently priced 48% below the average price you’ll pay for this route.

  • Can I find deals for flights from Manchester to Des Moines that include hotel bookings?

    Yes. In addition to deals on Manchester to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Manchester to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Manchester to Des Moines.

  • Can I find deals for business class flights from Manchester to Des Moines?

    Yes. Cheapflights offers flight deals from Manchester to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Manchester, New Hampshire to Des Moines?

    Currently, December is the cheapest month in which you can book a flight from Manchester, New Hampshire to Des Moines (average of $92). Flying from Manchester, New Hampshire to Des Moines in March is currently the most expensive (average of $333). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Ankeny
Ames
Boone
Clive
West Des Moines

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Top airline flying from Manchester to Des Moines

Discover the top airline that operate flights from Manchester to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 17, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$316Average$506FlexibilityNo cancel feeOn-time71%

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