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Des Moines

$501+ Cheap flights from Frankfurt (FRA) to Des Moines (DSM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/2. Fares are subject to change and may not be available on all flights or dates of travel.
FRA — DSM
Feb 25 — Mar 41
Wed 2/25
Wed 3/4
1 adult, Economy
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Cheap flight deals from Frankfurt to Des Moines

Cheapest flights from Frankfurt to Des Moines
Explore the most affordable flight options available from Frankfurt to Des Moines. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 26, 2026.

This American Airlines deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2210:55 am
FRA
-
DSM
1 stop35h 57m
American Airlines
Wed 7/81:41 pm
DSM
-
FRA
2 stops21h 34m
American Airlines
Deal found 1/24$728
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1010:55 am
FRA
-
DSM
1 stop34h 52m
American Airlines
Tue 5/512:06 pm
DSM
-
FRA
2 stops18h 44m
American Airlines
Deal found 1/26$732
This American Airlines deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2210:55 am
FRA
-
DSM
1 stop35h 57m
American Airlines
Sun 7/51:41 pm
DSM
-
FRA
1 stop34h 39m
American Airlines
Deal found 1/24$739
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:40 am
FRA
-
DSM
2 stops18h 55m
American Airlines
Mon 5/42:02 pm
DSM
-
FRA
2 stops18h 03m
American Airlines
Deal found 1/26$740
This Flighttix deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flighttix is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/110:15 am
FRA
-
DSM
1 stop19h 53m
British Airways
Sun 2/87:40 am
DSM
-
FRA
1 stop16h 35m
British Airways
Deal found 1/25$741
This American Airlines deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2210:55 am
FRA
-
DSM
2 stops19h 59m
American Airlines
Mon 7/65:30 am
DSM
-
FRA
2 stops18h 50m
American Airlines
Deal found 1/24$742
This British Airways deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:10 am
FRA
-
DSM
2 stops24h 19m
British Airways
Sat 5/22:18 pm
DSM
-
FRA
2 stops36h 02m
British Airways
Deal found 1/26$743
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/810:50 am
FRA
-
DSM
1 stop15h 10m
American Airlines
Wed 3/187:00 am
DSM
-
FRA
1 stop19h 50m
American Airlines
Deal found 1/25$745
This American Airlines deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/249:20 am
FRA
-
DSM
1 stop21h 31m
American Airlines
Wed 7/81:41 pm
DSM
-
FRA
2 stops21h 34m
American Airlines
Deal found 1/24$751
This American Airlines deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/239:20 am
FRA
-
DSM
1 stop21h 31m
American Airlines
Thu 7/97:00 am
DSM
-
FRA
2 stops21h 25m
American Airlines
Deal found 1/24$752

Find flight deals from Frankfurt to Des Moines

Discover tips and strategies to find the most affordable flight options for your journey from Frankfurt (FRA) to Des Moines (DSM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 26, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$728
(American Airlines)

One-way from

$501
(Finnair)

Popular in

January

Cheapest in

August

Average price

$1,390
Provider with most accurate pricing for Frankfurt am Main-Des Moines flight deals.
Search Deals
Provider most trusted by Cheapflights users for Frankfurt am Main-Des Moines flights.
Search Deals
From Frankfurt am Main to Des Moines
Search Deals
One-way flight from Frankfurt am Main to Des Moines
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($200 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($52 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Frankfurt to Des Moines that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 26, 2026.
Use the filters below to find and compare flights from Frankfurt am Main Airport to Des Moines that are best for you.

Fly from

Frankfurt

Fly to

Des Moines

Route

Depart

Return

Price

Frankfurt am MainDes Moines

FRA - DSM

FRADSM

Frankfurt am Main

Fri 4/10

9:20 am-9:53 pm

2 stops19h 33m

Des Moines

Tue 5/5

3:20 pm-7:50 pm

2 stops21h 30m

$732

Frankfurt am MainDes Moines

FRA - DSM

FRADSM

Frankfurt am Main

Sat 4/11

9:20 am-11:29 pm

2 stops21h 09m

Des Moines

Fri 5/1

2:18 pm-6:15 pm

2 stops20h 57m

$732

Frankfurt am MainDes Moines

FRA - DSM

FRADSM

Frankfurt am Main

Fri 4/10

10:55 am-11:10 am

1 stop31h 15m

Des Moines

Wed 5/6

2:02 pm-6:15 pm

2 stops21h 13m

$732

Frankfurt am MainDes Moines

FRA - DSM

FRADSM

Frankfurt am Main

Fri 4/10

6:10 am-7:31 pm

2 stops20h 21m

Des Moines

Sun 5/3

5:00 pm-10:25 pm

2 stops22h 25m

$739

Frankfurt am MainDes Moines

FRA - DSM

FRADSM

Frankfurt am Main

Tue 6/23

9:20 am-12:56 pm

1 stop34h 36m

Des Moines

Mon 7/6

5:30 am-7:20 am

2 stops18h 50m

$739

Frankfurt am MainDes Moines

FRA - DSM

FRADSM

Frankfurt am Main

Fri 4/10

6:10 am-11:29 pm

2 stops24h 19m

Des Moines

Sat 5/2

2:18 pm-9:20 am

2 stops36h 02m

$743

Frankfurt am MainDes Moines

FRA - DSM

FRADSM

Frankfurt am Main

Sat 4/11

4:40 pm-7:31 pm

2 stops33h 51m

Des Moines

Sat 5/2

8:01 pm-9:20 am

2 stops30h 19m

$743

Frankfurt am MainDes Moines

FRA - DSM

FRADSM

Frankfurt am Main

Sat 4/11

4:40 pm-11:29 pm

2 stops37h 49m

Des Moines

Sun 5/3

5:00 pm-9:30 am

2 stops33h 30m

$743

Frankfurt am MainDes Moines

FRA - DSM

FRADSM

Frankfurt am Main

Fri 4/10

9:20 am-9:53 pm

2 stops19h 33m

Des Moines

Sat 5/2

7:05 pm-8:45 am

1 stop30h 40m

$743

Frankfurt am MainDes Moines

FRA - DSM

FRADSM

Frankfurt am Main

Sat 4/11

9:20 am-11:29 pm

2 stops21h 09m

Des Moines

Wed 5/6

7:05 am-7:20 am

1 stop17h 15m

$743

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/24

Showing 1-10 of 18 results
1
2
  • Most accurate provider: When it comes to deals on Frankfurt am Main Airport-Des Moines flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Frankfurt am Main Airport-Des Moines flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Frankfurt am Main Airport-Des Moines flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Frankfurt am Main Airport-Des Moines flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Frankfurt am Main Airport-Des Moines flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Frankfurt to Des Moines

Have a flexible travel schedule? Discover the best time to fly to Des Moines from Frankfurt with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Des Moines

Get insights into the airlines that provide service to Des Moines. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Des Moines. Reviews last updated January 26, 2026.
Read through reviews of airlines operating flights from Frankfurt am Main Airport to Des Moines, such as United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,199 reviews

Boarding

7.7

Food

6.6

Entertainment

7.1

Comfort

7.3

Overall

7.4

Crew

8.1

Reviews

1 / 20
6.0
Good

Gerry,Jan 2026

YVR - DEN

Seats were uncomfortable. Second leg of my flight on United had much more comfortable seats
United Airlines
7.4
Good
9,199 reviews
United Airlines
7.4
Good
9,199 reviews

Boarding

7.7

Food

6.6

Entertainment

7.1

Comfort

7.3

Overall

7.4

Crew

8.1

Reviews

1 / 20
6.0
Good

Gerry,Jan 2026

YVR - DEN

Seats were uncomfortable. Second leg of my flight on United had much more comfortable seats

Related info for your journey

Find useful and relevant information for your journey from Frankfurt to Des Moines. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Des Moines from Frankfurt am Main?

    Des Moines (DSM), located 3.6 mi from the city center, is the airport you fly into when you book flights from Frankfurt am Main to Des Moines. 1 airline have flights to Des Moines from Frankfurt am Main on a regular basis. Booking flights from Frankfurt am Main to Des Moines should not be difficult; the airport handles an average of 0 inbound flights from Frankfurt am Main per day.

  • How long is the flight from Frankfurt am Main Airport to Des Moines?

    American Airlines and British Airways can get you from Frankfurt am Main Airport to Des Moines in just under 19h 33m. Your travel time can differ by up to 48m. There are 4558 mi between Frankfurt am Main Airport and Des Moines. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Frankfurt am Main Airport to Des Moines round-trip?

    Currently priced at $714, United Airlines will fly you from Frankfurt am Main Airport to Des Moines and back. In addition to United Airlines, many other airlines offer competitively priced options for your trip. This flight start at 22% lower than the current average price 3 months from now.

  • Can I find deals for flights from Frankfurt to Des Moines that include hotel bookings?

    Yes. In addition to deals on Frankfurt to Des Moines flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Frankfurt to Des Moines?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Frankfurt to Des Moines.

  • Can I find deals for business class flights from Frankfurt to Des Moines?

    Yes. Cheapflights offers flight deals from Frankfurt to Des Moines by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
Altoona
Johnston
Boone
Ames
Clive
West Des Moines
Ankeny

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Alternative routes for Frankfurt to Des Moines

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Top airline flying from Frankfurt to Des Moines

Discover the top airline that operate flights from Frankfurt to Des Moines. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 26, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$714Average$851FlexibilityNo cancel feeOn-time69%

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