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Cuzco

$416+ Cheap flights from Panama City (PTY) to Cusco (CUZ)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/20. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CUZ
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Panama City to Cuzco

Best flights from Panama City to Cuzco
Discover carefully curated flight deals from Panama City to Cuzco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 12, 2025.

This Priceline deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/142:55 amPTY - CUZ
1 stop8h 25mAvianca
Sat 1/245:10 pmCUZ - PTY
1 stop15h 40mAvianca
Deal found 12/10$421
This Mytrip deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/159:45 amPTY - CUZ
2 stops11h 41mMultiple Airlines
Sat 1/245:10 pmCUZ - PTY
1 stop15h 40mMultiple Airlines
Deal found 12/10$604
This Gotogate deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/2111:25 amPTY - CUZ
2 stops23h 55mAvianca
Wed 1/2812:25 pmCUZ - PTY
1 stop12h 15mAvianca
Deal found 12/10$595
This Kiwi.com deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/318:47 amPTY - CUZ
1 stop7h 14mMultiple Airlines
Mon 4/610:22 pmCUZ - PTY
1 stop7h 28mMultiple Airlines
Deal found 12/9$637
This Mytrip deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/215:50 pmPTY - CUZ
2 stops12h 35mMultiple Airlines
Wed 1/286:30 pmCUZ - PTY
2 stops14h 20mMultiple Airlines
Deal found 12/10$715
This Priceline deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/42:55 amPTY - CUZ
1 stop8h 25mAvianca
Fri 1/912:25 pmCUZ - PTY
1 stop12h 15mAvianca
Deal found 12/9$723

Find flight deals from Panama City to Cuzco

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Cuzco (CUZ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$416
(Gotogate)

Popular in

June

Cheapest in

February

Average price

$401
Provider with most accurate pricing for Panama City Tocumen Intl-Cusco Velazco Astete flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Cusco Velazco Astete flights.
Search Deals
From Panama City Tocumen Intl to Cusco Velazco Astete
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($42 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Cuzco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Panama City to Cusco that are best for you.

Fly from

Panama City

Fly to

Cuzco

Route

Depart

Return

Price

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Wed 1/14

2:55 am-11:20 am

1 stop8h 25m

Cusco Velazco Astete

Sat 1/24

5:10 pm-8:50 am

1 stop15h 40m

$421

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Wed 1/21

11:25 am-11:20 am

2 stops23h 55m

Cusco Velazco Astete

Wed 1/28

12:25 pm-12:40 am

1 stop12h 15m

$595

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Thu 1/15

9:45 am-9:26 pm

2 stops11h 41m

Cusco Velazco Astete

Sat 1/24

5:10 pm-8:50 am

1 stop15h 40m

$604

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Tue 3/31

8:47 am-4:01 pm

1 stop7h 14m

Cusco Velazco Astete

Mon 4/6

10:22 pm-5:50 am

1 stop7h 28m

$637

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Wed 1/21

5:50 pm-6:25 am

2 stops12h 35m

Cusco Velazco Astete

Wed 1/28

6:30 pm-8:50 am

2 stops14h 20m

$715

Panama CityCusco

PTY - CUZ

PTYCUZ

Panama City Tocumen Intl

Sun 1/4

2:55 am-11:20 am

1 stop8h 25m

Cusco Velazco Astete

Fri 1/9

12:25 pm-12:40 am

1 stop12h 15m

$723

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Compare providers for flights from Panama City to Cuzco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Cuzco in December.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City-Cusco flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Panama City-Cusco flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Panama City-Cusco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Cusco flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Cusco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Cusco

How far ahead should I book a flight from Panama City to Cusco?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to Cuzco. Price data was last updated on December 5, 2025.

Booking 58 days in advance of your planned departure date is, on average, the best time to get cheap flights from Panama City to Cusco. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Panama City to Cusco?

Currently, April is the cheapest month in which you can book a flight from Panama City to Cusco (average of $316). Flying from Panama City to Cusco in July is currently the most expensive (average of $372). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Cuzco

Get insights into the airlines that provide service to Cuzco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cuzco. Reviews last updated December 12, 2025.
Read through reviews of airlines operating flights from Panama City to Cusco, such as Avianca. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Avianca
6.6
Okay
2,480 reviews

Food

5.1

Comfort

6.3

Crew

7.2

Entertainment

5.4

Overall

6.6

Boarding

7.0

Reviews

1 / 20
8.0
Excellent

Anonymous,Aug 2025

MCO - BOG

The flights were on time and the staff was polite. No food on board that I can remember on the first let of my flight, no inflight entertainment either unless you use your device.
Avianca
6.6
Okay
2,480 reviews
Avianca
6.6
Okay
2,480 reviews

Food

5.1

Comfort

6.3

Crew

7.2

Entertainment

5.4

Overall

6.6

Boarding

7.0

Reviews

1 / 20
8.0
Excellent

Anonymous,Aug 2025

MCO - BOG

The flights were on time and the staff was polite. No food on board that I can remember on the first let of my flight, no inflight entertainment either unless you use your device.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Cuzco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City to Cusco?

    Avianca can get you from Panama City to Cusco in just under 8h 25m. Your travel time can differ by up to . Airlines will cover a distance of 1642 mi.

  • What is the cheapest airline to fly from Panama City to Cusco round-trip?

    Currently priced at $358, Avianca will fly you from Panama City to Cusco and back. In addition to Avianca, many other airlines offer competitively priced options for your trip. Avianca is currently priced 14% below the average price you’ll pay for this route.

  • Can I find deals for flights from Panama City to Cuzco that include hotel bookings?

    Yes. In addition to deals on Panama City to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Cuzco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Cuzco.

  • Can I find deals for business class flights from Panama City to Cuzco?

    Yes. Cheapflights offers flight deals from Panama City to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Cusco?

    Currently, April is the cheapest month in which you can book a flight from Panama City to Cusco (average of $316). Flying from Panama City to Cusco in July is currently the most expensive (average of $372). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama City to Cuzco

See prices for flight routes from nearby airports that may be better suited for you.
Panama City to Lima flights

Top airline flying from Panama City to Cuzco

Discover the top airline that operate flights from Panama City to Cuzco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$358Average$425FlexibilityNo cancel feeOn-time71%

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