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Cuzco

$244+ Cheap flights from Chicago (CHI) to Cusco (CUZ)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/1. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — CUZ
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Chicago to Cuzco

Discover tips and strategies to find the most affordable flight options for your journey from Chicago (CHI) to Cuzco (CUZ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$626
(Mytrip)

One-way from

$244
(Kiwi.com)

Popular in

December

Cheapest in

April

Average price

$630
From Chicago (CHI) to Cusco Velazco Astete
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One-way flight from Chicago (CHI) to Cusco Velazco Astete
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Highest demand for flights based on searches. 10% potential increase in price ($99 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($26 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Chicago to Cuzco

Cheapest flights from Chicago to Cuzco
Explore the most affordable flight options available from Chicago to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Mytrip deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2610:27 amORD - CUZ
2 stops22h 13mMultiple Airlines
Sat 11/112:05 amCUZ - ORD
2 stops25h 58mMultiple Airlines
Deal found 9/11$626
This Mytrip deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/45:05 amORD - CUZ
2 stops25h 19mMultiple Airlines
Tue 10/146:57 amCUZ - ORD
3 stops35h 41mMultiple Airlines
Deal found 9/9$650
This FlightHub deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/247:00 amORD - CUZ
2 stops17h 35mLATAM Airlines
Sat 11/17:35 amCUZ - ORD
2 stops16h 23mLATAM Airlines
Deal found 9/9$665
This FlightHub deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/275:51 pmORD - CUZ
2 stops15h 34mLATAM Airlines
Mon 11/109:05 pmCUZ - ORD
2 stops16h 34mLATAM Airlines
Deal found 9/10$676
This FlightHub deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/47:00 amORD - CUZ
2 stops23h 35mLATAM Airlines
Tue 10/146:40 amCUZ - ORD
2 stops17h 18mLATAM Airlines
Deal found 9/8$679
This Mytrip deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/244:44 pmORD - CUZ
3 stops30h 36mMultiple Airlines
Fri 10/317:02 amCUZ - ORD
3 stops35h 36mMultiple Airlines
Deal found 9/9$682
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/271:51 pmORD - CUZ
2 stops20h 30mAmerican Airlines
Mon 11/108:57 pmCUZ - ORD
2 stops16h 07mAmerican Airlines
Deal found 9/11$684
This Mytrip deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2711:20 pmORD - CUZ
1 stop12h 00mMultiple Airlines
Sat 11/112:05 amCUZ - ORD
2 stops25h 58mMultiple Airlines
Deal found 9/9$690
This LATAM Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/296:30 pmMDW - CUZ
2 stops14h 35mLATAM Airlines
Tue 10/77:00 pmCUZ - MDW
2 stops14h 40mLATAM Airlines
Deal found 9/9$692
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/273:45 pmORD - CUZ
2 stops17h 15mDelta
Mon 10/67:30 amCUZ - ORD
2 stops16h 28mDelta
Deal found 9/9$692
This Expedia deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/275:04 pmMDW - CUZ
2 stops15h 56mLATAM Airlines
Sun 11/211:20 pmCUZ - MDW
2 stops23h 54mLATAM Airlines
Deal found 9/9$722
This LATAM Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/275:04 pmMDW - CUZ
2 stops15h 56mLATAM Airlines
Mon 11/107:35 amCUZ - MDW
2 stops16h 57mLATAM Airlines
Deal found 9/11$846

Cheapflights Fare Finder

 
Customize your flight search to find flights from Chicago to Cuzco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Chicago to Cusco that are best for you.

Fly from

Chicago

Fly to

Cuzco

Route

Depart

Return

Price

ChicagoCusco

ORD - CUZ

ORDCUZ

Chicago O'Hare Intl

Sun 10/26

10:27 am-8:40 am

2 stops22h 13m

Cusco Velazco Astete

Sat 11/1

12:05 am-2:03 am

2 stops25h 58m

$626

ChicagoCusco

ORD - CUZ

ORDCUZ

Chicago O'Hare Intl

Mon 10/27

5:51 pm-9:25 am

2 stops15h 34m

Cusco Velazco Astete

Mon 11/10

8:15 pm-12:39 pm

2 stops17h 24m

$676

ChicagoCusco

ORD - CUZ

ORDCUZ

Chicago O'Hare Intl

Sat 10/4

7:00 am-6:35 am

2 stops23h 35m

Cusco Velazco Astete

Tue 10/14

6:40 am-11:58 pm

2 stops17h 18m

$679

ChicagoCusco

ORD - CUZ

ORDCUZ

Chicago O'Hare Intl

Sat 1/17

8:00 am-12:45 am

2 stops15h 45m

Cusco Velazco Astete

Thu 1/29

6:50 am-11:54 pm

2 stops18h 04m

$679

ChicagoCusco

ORD - CUZ

ORDCUZ

Chicago O'Hare Intl

Fri 1/16

9:30 am-12:45 am

2 stops14h 15m

Cusco Velazco Astete

Thu 1/29

7:35 am-11:54 pm

2 stops17h 19m

$679

ChicagoCusco

ORD - CUZ

ORDCUZ

Chicago O'Hare Intl

Sat 2/21

8:50 am-11:20 am

2 stops25h 30m

Cusco Velazco Astete

Sun 3/1

12:25 pm-10:36 pm

2 stops35h 11m

$681

ChicagoCusco

ORD - CUZ

ORDCUZ

Chicago O'Hare Intl

Thu 11/13

4:40 pm-10:46 am

2 stops17h 06m

Cusco Velazco Astete

Mon 11/17

8:57 pm-11:06 am

2 stops15h 09m

$684

ChicagoCusco

ORD - CUZ

ORDCUZ

Chicago O'Hare Intl

Sun 2/22

10:20 pm-11:20 am

1 stop12h 00m

Cusco Velazco Astete

Sat 2/28

5:10 pm-8:20 pm

1 stop28h 10m

$686

ChicagoCusco

MDW - CUZ

MDWCUZ

Chicago Midway

Fri 1/16

6:00 am-12:45 am

2 stops17h 45m

Cusco Velazco Astete

Thu 1/29

7:50 pm-12:01 pm

2 stops17h 11m

$692

ChicagoCusco

MDW - CUZ

MDWCUZ

Chicago Midway

Sat 1/17

10:35 am-12:45 am

2 stops13h 10m

Cusco Velazco Astete

Thu 1/29

8:10 pm-4:25 pm

2 stops21h 15m

$692

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 31 results
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Best time to book a flight from Chicago to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from Chicago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Chicago to Cusco

How far ahead should I book a flight from Chicago to Cusco?

Use this chart to determine the optimal time to book a round-trip flight from Chicago to Cuzco. Price data was last updated on August 29, 2025.

Booking 35 days in advance of your planned departure date is, on average, the best time to get cheap flights from Chicago to Cusco. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Chicago to Cusco?

Currently, February is the cheapest month in which you can book a flight from Chicago to Cusco (average of $789). Flying from Chicago to Cusco in December is currently the most expensive (average of $1,346). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CHI to CUZ?

Find hourly flight availability from Chicago to Cuzco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

A simple way to save on the total cost of your ticket is to fly from Chicago to Cusco at noon. If you’re flexible enough to do this you can expect to save up to 34% on your trip compared to booking a flight in the morning.

Reviews of airlines servicing Cuzco

Get insights into the airlines that provide service to Cuzco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cuzco. Reviews last updated September 11, 2025.
Read reviews from past customers who have flown Delta, LATAM Airlines, and American Airlines from Chicago to Cusco. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,847 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Avianca
6.7
Okay
2,436 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Chicago to Cuzco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Cusco from Chicago?

    For a flight from Chicago to Cusco, you will be flying into Velazco Astete. Cusco Velazco Astete (CUZ) is just 1.7 mi from the center of the city. Velazco Astete is the only Cusco airport and it handles 0 inbound flights from Chicago per day. 4 airlines have flights to Cusco Velazco Astete from Chicago on a regular basis.

  • How long is the flight from Chicago to Cusco?

    LATAM Airlines and Delta can get you from Chicago to Cusco in just under 15h 34m. Your travel time can differ by up to 2h 11m. The distance between Chicago and Cusco is about 3965 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Chicago to Cusco round-trip?

    Flying on Avianca is currently your cheapest option to Cusco, with prices starting at $420. Additional round-trip tickets that might be worth considering are offered by LATAM Airlines and American Airlines, with the lowest prices starting at $635 and $721, respectively. You may be able to fly from Chicago to Cusco for 48% less than the average price by searching for these airlines.

  • Can I find deals for flights from Chicago to Cuzco that include hotel bookings?

    Yes. In addition to deals on Chicago to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Chicago to Cuzco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Chicago to Cuzco.

  • Can I find deals for business class flights from Chicago to Cuzco?

    Yes. Cheapflights offers flight deals from Chicago to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Chicago to Cusco?

    Currently, February is the cheapest month in which you can book a flight from Chicago to Cusco (average of $789). Flying from Chicago to Cusco in December is currently the most expensive (average of $1,346). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Chicago to Cuzco

Discover the top 4 airlines that operate flights from Chicago to Cuzco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$420Average$599FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$635Average$993FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$721Average$897FlexibilityNo cancel feeOn-time71%
DeltaCheapest$776Average$899FlexibilityNo cancel feeOn-timeN/A

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