$123+ Cheap flights from St. Louis (STL) to Columbus
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/26. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CMH
Dec 9 — Dec 161
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from St. Louis to Columbus with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Columbus
Cheapest
Best
Last-minute
One-way
Cheapest flights from St. Louis to ColumbusExplore the most affordable flight options available from St. Louis to Columbus. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 9, 2026.
Explore the most affordable flight options available from St. Louis to Columbus. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:20 pm -
2 stops23h 07m
Thu 12/105:32 pm -
1 stop18h 45m
Deal found 11/6![Multiple Airlines logo]()
$231
This CheapOair deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:13 pm -
1 stop14h 25m
Tue 12/810:33 am -
1 stop14h 39m
Deal found 11/5![Frontier logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/236:21 pm -
1 stop23h 32m
Tue 12/297:54 pm -
1 stop15h 59m
Deal found 11/5![Frontier logo]()
$245
This Trip.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:20 pm -
1 stop14h 18m
Thu 12/107:01 pm -
1 stop16h 56m
Deal found 11/6![Frontier logo]()
$246
This Trip.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:13 pm -
1 stop14h 25m
Mon 12/710:33 am -
1 stop14h 39m
Deal found 11/5![Frontier logo]()
$254
This CheapOair deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:20 pm -
1 stop14h 18m
Sun 12/132:32 pm -
1 stop10h 40m
Deal found 11/5![Frontier logo]()
$258
This CheapOair deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/201:20 pm -
1 stop19h 13m
Sat 11/215:35 pm -
1 stop7h 24m
Deal found 11/5![Frontier logo]()
$277
This Trip.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/226:05 pm -
1 stop14h 28m
Thu 11/266:53 pm -
1 stop17h 10m
Deal found 11/6![Frontier logo]()
$285
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/185:31 pm -
1 stop6h 02m
Tue 12/226:15 pm -
1 stop6h 40m
Deal found 11/5![Delta logo]()
$286
This CheapOair deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/66:20 pm -
1 stop14h 18m
Sun 12/137:01 pm -
1 stop16h 56m
Deal found 11/7![Frontier logo]()
$296
Best flights from St. Louis to ColumbusDiscover carefully curated flight deals from St. Louis to Columbus that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 9, 2026.
Discover carefully curated flight deals from St. Louis to Columbus that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 9, 2026.
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/75:30 pm -
Nonstop1h 20m
Sat 1/97:00 am -
1 stop8h 05m
Deal found 11/4![Southwest logo]()
$327
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/295:00 am -
1 stop5h 42m
Thu 12/34:15 pm -
1 stop4h 11m
Deal found 11/5![United Airlines logo]()
$366
This Southwest deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/410:15 am -
Nonstop1h 15m
Mon 12/711:25 am -
1 stop7h 40m
Deal found 11/5![Southwest logo]()
$327
This Southwest deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/237:55 pm -
Nonstop1h 25m
Tue 12/295:15 pm -
1 stop7h 40m
Deal found 11/5![Southwest logo]()
$327
This Southwest deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/298:10 am -
1 stop5h 30m
Tue 12/298:30 pm -
Nonstop1h 30m
Deal found 11/6![Southwest logo]()
$349
This Southwest deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:10 pm -
Nonstop1h 20m
Thu 12/106:20 am -
Nonstop1h 40m
Deal found 11/6![Southwest logo]()
$354
This Southwest deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/176:10 am -
1 stop7h 55m
Tue 12/228:30 pm -
Nonstop1h 30m
Deal found 11/8![Southwest logo]()
$364
This Southwest deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/218:10 am -
1 stop5h 30m
Mon 12/218:30 pm -
Nonstop1h 30m
Deal found 11/8![Southwest logo]()
$379
This Southwest deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1710:15 am -
Nonstop1h 20m
Mon 12/213:30 pm -
1 stop8h 05m
Deal found 11/8![Southwest logo]()
$379
This Southwest deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/114:40 pm -
2 stops6h 10m
Wed 12/307:55 pm -
1 stop3h 50m
Deal found 11/7![Southwest logo]()
$387
Last-minute flights from St. Louis to ColumbusDiscover last-minute flight deals from St. Louis to Columbus. Data last updated November 9, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Columbus. Data last updated November 9, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/201:20 pm -
1 stop19h 13m
Sat 11/215:35 pm -
1 stop7h 24m
Deal found 11/5![Frontier logo]()
$277
This Trip.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/226:05 pm -
1 stop14h 28m
Thu 11/266:53 pm -
1 stop17h 10m
Deal found 11/6![Frontier logo]()
$285
This CheapOair deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:13 pm -
1 stop14h 25m
Tue 12/810:33 am -
1 stop14h 39m
Deal found 11/5![Frontier logo]()
$239
This Trip.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:13 pm -
1 stop14h 25m
Mon 12/710:33 am -
1 stop14h 39m
Deal found 11/5![Frontier logo]()
$254
This CheapOair deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/66:20 pm -
1 stop14h 18m
Sun 12/137:01 pm -
1 stop16h 56m
Deal found 11/7![Frontier logo]()
$296
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:20 pm -
2 stops23h 07m
Thu 12/105:32 pm -
1 stop18h 45m
Deal found 11/6![Multiple Airlines logo]()
$231
This Trip.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:20 pm -
1 stop14h 18m
Thu 12/107:01 pm -
1 stop16h 56m
Deal found 11/6![Frontier logo]()
$246
This CheapOair deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:20 pm -
1 stop14h 18m
Sun 12/132:32 pm -
1 stop10h 40m
Deal found 11/5![Frontier logo]()
$258
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/185:31 pm -
1 stop6h 02m
Tue 12/226:15 pm -
1 stop6h 40m
Deal found 11/5![Delta logo]()
$286
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/236:21 pm -
1 stop23h 32m
Tue 12/297:54 pm -
1 stop15h 59m
Deal found 11/5![Frontier logo]()
$245
One-way flights from St. Louis to ColumbusSearch for one-way flight options from St. Louis to Columbus. Find affordable one-way fares based on user searches. Data last updated November 9, 2026.
Search for one-way flight options from St. Louis to Columbus. Find affordable one-way fares based on user searches. Data last updated November 9, 2026.
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/263:15 pm -
1 stop4h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Delta logo]()
$123
This CheapOair deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:20 pm -
1 stop18h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Frontier logo]()
$148
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/269:40 am -
Nonstop1h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Southwest logo]()
$159
This Trip.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/236:20 pm -
1 stop18h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/7![Frontier logo]()
$162
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:00 am -
1 stop7h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Delta logo]()
$164
This Southwest deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/237:55 pm -
Nonstop1h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/7![Southwest logo]()
$170
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:30 am -
1 stop6h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![United Airlines logo]()
$198
Find flight deals from St. Louis to Columbus
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Columbus (C01). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 9, 2026.
Round-trip from | $231 (Kiwi.com) |
|---|---|
One-way from | $123 (Delta) |
Popular in | February |
Cheapest in | January |
Average price | $499 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Columbus that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 9, 2026.
Use the filters below to find and compare flights from St. Louis to Columbus that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisColumbus
STL Lambert-St Louis - CMH Columbus
STLCMH
Lambert-St Louis
Thu 11/26
3:15 pm-8:37 pm
1 stop4h 22m
Columbus
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$123
Quickest round-trip
St. LouisColumbus
STL Lambert-St Louis - CMH Columbus
STLCMH
Lambert-St Louis
Thu 11/26
9:40 am-12:00 pm
Nonstop1h 20m
Columbus
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$159
St. LouisColumbus
STL Lambert-St Louis - CMH Columbus
STLCMH
Lambert-St Louis
Wed 12/23
6:20 pm-1:26 pm
1 stop18h 06m
Columbus
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$162
St. LouisColumbus
STL Lambert-St Louis - CMH Columbus
STLCMH
Lambert-St Louis
Fri 12/18
6:00 am-2:06 pm
1 stop7h 06m
Columbus
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$164
St. LouisColumbus
STL Lambert-St Louis - CMH Columbus
STLCMH
Lambert-St Louis
Wed 12/23
7:55 pm-10:20 pm
Nonstop1h 25m
Columbus
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$170
St. LouisColumbus
STL Lambert-St Louis - CMH Columbus
STLCMH
Lambert-St Louis
Wed 11/18
7:30 am-3:15 pm
1 stop6h 45m
Columbus
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$198
St. LouisColumbus
STL Lambert-St Louis - CMH Columbus
STLCMH
Lambert-St Louis
Fri 4/2
11:45 am-5:11 pm
1 stop4h 26m
Columbus
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$203
St. LouisColumbus
STL Lambert-St Louis - CMH Columbus
STLCMH
Lambert-St Louis
Wed 11/18
10:55 am-6:10 pm
2 stops6h 15m
Columbus
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$208
St. LouisColumbus
STL Lambert-St Louis - CMH Columbus
STLCMH
Lambert-St Louis
Thu 1/7
5:30 pm-7:50 pm
Nonstop1h 20m
Columbus
Sat 1/9
7:00 am-2:05 pm
1 stop8h 05m
$327
St. LouisColumbus
STL Lambert-St Louis - CMH Columbus
STLCMH
Lambert-St Louis
Fri 12/4
10:15 am-12:30 pm
Nonstop1h 15m
Columbus
Mon 12/7
11:25 am-6:05 pm
1 stop7h 40m
$327
Showing 1-10 of 18 resultsSorted by cheapest first
Best time to book a flight from St. Louis to Columbus
Have a flexible travel schedule? Discover the best time to fly to Columbus from St. Louis with our price prediction graph.
STL-C01
STL-CMH
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Columbus
STL-C01
STL-CMH
What is the cheapest month to book a flight from St. Louis to Columbus?
Currently, January is the cheapest month in which you can book a flight from St. Louis to Columbus (average of $332). Flying from St. Louis to Columbus in February is currently the most expensive (average of $659). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from STL to CMH?
Find hourly flight availability from St. Louis to Columbus. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 9, 2026.
It’s optimal to fly from St. Louis to Columbus in the evening. By choosing this option you can save up to 35% on the cost of your flight, compared to a flight at noon.
Reviews of airlines servicing Columbus
Get insights into the airlines that provide service to Columbus. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Columbus. Reviews last updated November 9, 2026.
See what other customers who have flown with Southwest from St. Louis to Columbus have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Overall
8.0
Boarding
8.1
Comfort
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Entertainment
7.5
Overall
8.0
Boarding
8.1
Comfort
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Columbus. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from St. Louis
Popular flights
Alternative routes for St. Louis to Columbus
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Columbus by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from St. Louis to Columbus by cabin class
Find flights from St. Louis to Columbus, based on your preferred cabin class, be it economy, premium economy, business, or first class.
St. Louis and Columbus flights
Browse other St. Louis and Columbus flight options. Last updated on November 9, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on November 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from St. Louis to Columbus
Discover the top 2 airlines that operate flights from St. Louis to Columbus. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$230 | Average$384 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$273 | Average$438 | FlexibilityNo cancel fee | On-time69% |