$64+ Cheap flights from St. Louis (STL) to Columbus
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/29. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CMH
Aug 5 — Aug 121
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from St. Louis to Columbus with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Columbus
Cheapest
Best
Last-minute
One-way
Cheapest flights from St. Louis to ColumbusExplore the most affordable flight options available from St. Louis to Columbus. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 6, 2026.
Explore the most affordable flight options available from St. Louis to Columbus. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 6, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/104:57 pm
STL
- CMH
1 stop23h 02m
Frontier
Thu 8/135:44 pm
CMH
- STL
1 stop16h 13m
Frontier
Deal found 7/1![Frontier logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2010:35 am
STL
- CMH
1 stop5h 58m
Frontier
Thu 10/226:11 pm
CMH
- STL
1 stop16h 29m
Frontier
Deal found 7/2![Frontier logo]()
$143
This Kiwi.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:34 pm
STL
- CMH
2 stops38h 09m
Frontier
Tue 8/115:44 pm
CMH
- STL
1 stop16h 13m
Frontier
Deal found 7/3![Frontier logo]()
$220
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2010:35 am
STL
- CMH
1 stop5h 58m
Multiple Airlines
Thu 10/229:09 am
CMH
- STL
2 stops25h 31m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:34 pm
STL
- CMH
2 stops15h 43m
Multiple Airlines
Thu 8/135:44 pm
CMH
- STL
1 stop16h 13m
Multiple Airlines
Deal found 7/1![Multiple Airlines logo]()
$229
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:17 pm
STL
- CMH
2 stops14h 13m
Multiple Airlines
Thu 8/276:10 pm
CMH
- STL
1 stop24h 12m
Multiple Airlines
Deal found 7/6![Multiple Airlines logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/84:57 pm
STL
- CMH
1 stop23h 02m
Frontier
Sat 8/156:06 pm
CMH
- STL
2 stops39h 51m
Frontier
Deal found 7/5![Frontier logo]()
$245
Best flights from St. Louis to ColumbusDiscover carefully curated flight deals from St. Louis to Columbus that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 6, 2026.
Discover carefully curated flight deals from St. Louis to Columbus that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 6, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2010:35 am
STL
- CMH
1 stop5h 58m
Frontier
Thu 10/226:11 pm
CMH
- STL
1 stop16h 29m
Frontier
Deal found 7/2![Frontier logo]()
$143
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:01 pm
STL
- CMH
1 stop3h 53m
United Airlines
Mon 10/196:01 pm
CMH
- STL
1 stop4h 20m
United Airlines
Deal found 7/2![United Airlines logo]()
$265
This Southwest deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/810:15 am
STL
- CMH
Nonstop1h 20m
Southwest
Mon 8/107:20 am
CMH
- STL
Nonstop1h 25m
Southwest
Deal found 7/1![Southwest logo]()
$271
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:30 am
STL
- CMH
1 stop5h 57m
Delta
Mon 8/106:23 pm
CMH
- STL
1 stop6h 35m
Delta
Deal found 7/1![Delta logo]()
$281
This Booking.com deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/84:09 pm
STL
- CMH
1 stop16h 34m
Frontier
Sat 8/156:06 pm
CMH
- STL
1 stop6h 53m
Frontier
Deal found 7/5![Frontier logo]()
$258
This Southwest deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/412:50 pm
STL
- CMH
1 stop4h 55m
Southwest
Tue 8/117:25 pm
CMH
- STL
Nonstop1h 25m
Southwest
Deal found 7/3![Southwest logo]()
$293
This Booking.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/98:08 pm
STL
- CMH
1 stop17h 19m
Frontier
Thu 8/1310:28 am
CMH
- STL
1 stop14h 31m
Frontier
Deal found 7/2![Frontier logo]()
$277
This Southwest deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/94:05 pm
STL
- CMH
1 stop6h 00m
Southwest
Thu 8/137:20 am
CMH
- STL
Nonstop1h 25m
Southwest
Deal found 7/2![Southwest logo]()
$304
This Southwest deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:45 am
STL
- CMH
1 stop3h 15m
Southwest
Sat 9/512:50 pm
CMH
- STL
2 stops8h 50m
Southwest
Deal found 7/3![Southwest logo]()
$308
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2010:10 am
STL
- CMH
Nonstop1h 20m
Southwest
Thu 8/277:35 pm
CMH
- STL
Nonstop1h 25m
Southwest
Deal found 7/6![Southwest logo]()
$309
Last-minute flights from St. Louis to ColumbusDiscover last-minute flight deals from St. Louis to Columbus. Data last updated July 6, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Columbus. Data last updated July 6, 2026 and is based on user searches.
This Trip.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/224:09 pm
STL
- CMH
1 stop27h 05m
Frontier
Fri 7/248:59 pm
CMH
- STL
1 stop28h 00m
Frontier
Deal found 7/1![Frontier logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:34 pm
STL
- CMH
2 stops38h 09m
Frontier
Tue 8/115:44 pm
CMH
- STL
1 stop16h 13m
Frontier
Deal found 7/3![Frontier logo]()
$220
This Kiwi.com deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/84:57 pm
STL
- CMH
1 stop23h 02m
Frontier
Sat 8/156:06 pm
CMH
- STL
2 stops39h 51m
Frontier
Deal found 7/5![Frontier logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:34 pm
STL
- CMH
2 stops15h 43m
Multiple Airlines
Thu 8/135:44 pm
CMH
- STL
1 stop16h 13m
Multiple Airlines
Deal found 7/1![Multiple Airlines logo]()
$229
This Trip.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/94:09 pm
STL
- CMH
1 stop27h 05m
Frontier
Thu 8/1310:28 am
CMH
- STL
1 stop14h 31m
Frontier
Deal found 7/1![Frontier logo]()
$268
This Kiwi.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/104:57 pm
STL
- CMH
1 stop23h 02m
Frontier
Thu 8/135:44 pm
CMH
- STL
1 stop16h 13m
Frontier
Deal found 7/1![Frontier logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:17 pm
STL
- CMH
2 stops14h 13m
Multiple Airlines
Thu 8/276:10 pm
CMH
- STL
1 stop24h 12m
Multiple Airlines
Deal found 7/6![Multiple Airlines logo]()
$242
One-way flights from St. Louis to ColumbusSearch for one-way flight options from St. Louis to Columbus. Find affordable one-way fares based on user searches. Data last updated July 6, 2026.
Search for one-way flight options from St. Louis to Columbus. Find affordable one-way fares based on user searches. Data last updated July 6, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2910:35 am
STL
- CMH
1 stop5h 58m
Frontier
Deal found 7/2![Frontier logo]()
$64
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:17 pm
STL
- CMH
1 stop22h 08m
Frontier
Deal found 7/2![Frontier logo]()
$74
This Kiwi.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/14:57 pm
STL
- CMH
1 stop23h 02m
Frontier
Deal found 7/3![Frontier logo]()
$75
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/274:57 pm
STL
- CMH
1 stop23h 02m
Frontier
Deal found 7/2![Frontier logo]()
$85
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2710:35 am
STL
- CMH
1 stop5h 58m
Frontier
Deal found 7/2![Frontier logo]()
$98
This Trip.com deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/48:08 pm
STL
- CMH
1 stop17h 19m
Frontier
Deal found 7/5![Frontier logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:17 pm
STL
- CMH
2 stops17h 05m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$117
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/295:33 pm
STL
- CMH
1 stop17h 10m
Delta
Deal found 7/3![Delta logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/284:09 pm
STL
- CMH
1 stop27h 05m
Frontier
Deal found 7/2![Frontier logo]()
$120
This Frontier deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/410:35 am
STL
- CMH
1 stop5h 58m
Frontier
Deal found 7/3![Frontier logo]()
$123
This Delta deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/285:23 pm
STL
- CMH
1 stop16h 06m
Delta
Deal found 7/1![Delta logo]()
$128
Find flight deals from St. Louis to Columbus
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Columbus (C01). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 6, 2026.
Round-trip from | $142 (Kiwi.com) |
|---|---|
One-way from | $64 (Kiwi.com) |
Popular in | February |
Cheapest in | January |
Average price | $371 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Columbus that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 6, 2026.
Use the filters below to find and compare flights from St. Louis to Columbus that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisColumbus
STL - CMH
STLCMH
Lambert-St Louis
Tue 10/20
10:35 am-5:33 pm
1 stop5h 58m
Columbus
Thu 10/22
6:11 pm-9:40 am
1 stop16h 29m
$143
St. LouisColumbus
STL - CMH
STLCMH
Lambert-St Louis
Sat 8/8
4:09 pm-9:43 am
1 stop16h 34m
Columbus
Sat 8/15
6:06 pm-11:59 pm
1 stop6h 53m
$258
St. LouisColumbus
STL - CMH
STLCMH
Lambert-St Louis
Sat 10/17
7:01 pm-11:54 pm
1 stop3h 53m
Columbus
Mon 10/19
6:01 pm-9:21 pm
1 stop4h 20m
$265
Quickest round-trip
St. LouisColumbus
STL - CMH
STLCMH
Lambert-St Louis
Sat 8/8
10:15 am-12:35 pm
Nonstop1h 20m
Columbus
Mon 8/10
7:20 am-7:45 am
Nonstop1h 25m
$271
St. LouisColumbus
STL - CMH
STLCMH
Lambert-St Louis
Sun 8/9
8:08 pm-2:27 pm
1 stop17h 19m
Columbus
Thu 8/13
10:28 am-11:59 pm
1 stop14h 31m
$277
St. LouisColumbus
STL - CMH
STLCMH
Lambert-St Louis
Sat 8/8
6:30 am-1:27 pm
1 stop5h 57m
Columbus
Mon 8/10
6:23 pm-11:58 pm
1 stop6h 35m
$281
St. LouisColumbus
STL - CMH
STLCMH
Lambert-St Louis
Tue 8/4
12:50 pm-6:45 pm
1 stop4h 55m
Columbus
Tue 8/11
7:25 pm-7:50 pm
Nonstop1h 25m
$293
St. LouisColumbus
STL - CMH
STLCMH
Lambert-St Louis
Sun 8/9
4:05 pm-11:05 pm
1 stop6h 00m
Columbus
Thu 8/13
7:20 am-7:45 am
Nonstop1h 25m
$304
St. LouisColumbus
STL - CMH
STLCMH
Lambert-St Louis
Sat 9/5
5:45 am-10:00 am
1 stop3h 15m
Columbus
Sat 9/5
12:50 pm-8:40 pm
2 stops8h 50m
$308
St. LouisColumbus
STL - CMH
STLCMH
Lambert-St Louis
Thu 8/20
10:10 am-12:30 pm
Nonstop1h 20m
Columbus
Thu 8/27
7:35 pm-8:00 pm
Nonstop1h 25m
$309
Showing 1-10 of 21 resultsSorted by cheapest first
Best time to book a flight from St. Louis to Columbus
Have a flexible travel schedule? Discover the best time to fly to Columbus from St. Louis with our price prediction graph.
STL-C01
STL-CMH
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Columbus
STL-C01
STL-CMH
What is the cheapest month to book a flight from St. Louis to Columbus?
Currently, October is the cheapest month in which you can book a flight from St. Louis to Columbus (average of $168). Flying from St. Louis to Columbus in February is currently the most expensive (average of $395). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from STL to CMH?
Find hourly flight availability from St. Louis to Columbus. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 6, 2026.
It’s optimal to fly from St. Louis to Columbus in the evening. By choosing this option you can save up to 49% on the cost of your flight, compared to a flight in the afternoon.
How much does it cost to fly round-trip from St. Louis to Columbus?
Reviews of airlines servicing Columbus
Get insights into the airlines that provide service to Columbus. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Columbus. Reviews last updated July 6, 2026.
See what other customers who have flown with Southwest from St. Louis to Columbus have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Overall
7.9
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Columbus. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from St. Louis
Popular flights
Alternative routes for St. Louis to Columbus
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Columbus by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from St. Louis to Columbus by cabin class
Find flights from St. Louis to Columbus, based on your preferred cabin class, be it economy, premium economy, business, or first class.
St. Louis and Columbus flights
Browse other St. Louis and Columbus flight options. Last updated on July 6, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on July 6, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from St. Louis to Columbus
Discover the top 3 airlines that operate flights from St. Louis to Columbus. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 6, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$215 | Average$364 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$233 | Average$358 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$278 | Average$318 | FlexibilityNo cancel fee | On-time71% |