$53+ Cheap flights from St. Louis (STL) to Columbus
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/8. Fares are subject to change and may not be available on all flights or dates of travel.
STL — CMH
Sep 6 — Sep 131
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to Columbus with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Columbus
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Best
Last-minute
One-way
Cheapest flights from St. Louis to ColumbusExplore the most affordable flight options available from St. Louis to Columbus. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 7, 2026.
Explore the most affordable flight options available from St. Louis to Columbus. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/810:35 am -
1 stop5h 58m
Sun 10/116:11 pm -
1 stop16h 29m
Deal found 8/7![Frontier logo]()
$105
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/302:29 pm -
1 stop27h 26m
Wed 10/74:30 pm -
2 stops18h 10m
Deal found 8/3![Frontier logo]()
$167
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:17 pm -
2 stops38h 26m
Sun 9/137:50 pm -
1 stop18h 20m
Deal found 8/6![Frontier logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2310:35 am -
2 stops22h 57m
Sun 10/256:11 pm -
1 stop16h 29m
Deal found 8/7![Frontier logo]()
$176
This Trip.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:02 pm -
1 stop15h 41m
Sat 8/2910:28 am -
1 stop6h 43m
Deal found 8/6![Frontier logo]()
$197
This Trip.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:02 pm -
1 stop15h 41m
Wed 8/268:27 pm -
1 stop23h 46m
Deal found 8/3![Frontier logo]()
$230
This Trip.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/44:23 pm -
1 stop16h 20m
Sun 9/610:28 am -
1 stop6h 43m
Deal found 8/5![Frontier logo]()
$252
This Trip.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/214:23 pm -
1 stop16h 20m
Mon 8/2410:28 am -
1 stop6h 00m
Deal found 8/7![Frontier logo]()
$253
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/65:50 pm -
Nonstop1h 20m
Mon 9/77:20 am -
Nonstop1h 25m
Deal found 8/5![Southwest logo]()
$254
Best flights from St. Louis to ColumbusDiscover carefully curated flight deals from St. Louis to Columbus that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 7, 2026.
Discover carefully curated flight deals from St. Louis to Columbus that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 7, 2026.
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/91:40 pm -
1 stop5h 24m
Fri 9/116:00 am -
1 stop4h 34m
Deal found 8/4![Delta logo]()
$269
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:15 am -
1 stop4h 30m
Wed 9/301:45 pm -
1 stop7h 15m
Deal found 8/3![Southwest logo]()
$277
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:50 pm -
Nonstop1h 25m
Fri 9/117:20 am -
Nonstop1h 25m
Deal found 8/5![Southwest logo]()
$281
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/45:23 pm -
1 stop6h 35m
Sat 9/56:00 am -
1 stop4h 20m
Deal found 8/5![Delta logo]()
$296
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/65:50 pm -
Nonstop1h 20m
Sun 9/1311:20 am -
1 stop4h 10m
Deal found 8/6![Southwest logo]()
$286
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1610:05 am -
1 stop7h 05m
Fri 9/186:00 am -
1 stop4h 00m
Deal found 8/4![Delta logo]()
$308
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1612:40 pm -
1 stop4h 30m
Mon 11/233:00 pm -
2 stops7h 00m
Deal found 8/3![Southwest logo]()
$296
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/232:00 pm -
1 stop3h 25m
Sun 10/257:10 am -
Nonstop1h 25m
Deal found 8/7![Southwest logo]()
$297
This Delta deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/189:15 am -
1 stop7h 12m
Sat 8/227:08 am -
1 stop5h 48m
Deal found 8/3![Delta logo]()
$335
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:50 pm -
Nonstop1h 25m
Fri 9/251:40 pm -
1 stop4h 05m
Deal found 8/5![Southwest logo]()
$303
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:30 pm -
1 stop5h 50m
Wed 8/267:55 am -
2 stops8h 15m
Deal found 8/6![Southwest logo]()
$340
Last-minute flights from St. Louis to ColumbusDiscover last-minute flight deals from St. Louis to Columbus. Data last updated August 7, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Columbus. Data last updated August 7, 2026 and is based on user searches.
This Trip.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/214:23 pm -
1 stop16h 20m
Mon 8/2410:28 am -
1 stop6h 00m
Deal found 8/7![Frontier logo]()
$253
This Trip.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:02 pm -
1 stop15h 41m
Wed 8/268:27 pm -
1 stop23h 46m
Deal found 8/3![Frontier logo]()
$230
This Trip.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:02 pm -
1 stop15h 41m
Sat 8/2910:28 am -
1 stop6h 43m
Deal found 8/6![Frontier logo]()
$197
This Trip.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/44:23 pm -
1 stop16h 20m
Sun 9/610:28 am -
1 stop6h 43m
Deal found 8/5![Frontier logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:17 pm -
2 stops38h 26m
Sun 9/137:50 pm -
1 stop18h 20m
Deal found 8/6![Frontier logo]()
$171
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/65:50 pm -
Nonstop1h 20m
Mon 9/77:20 am -
Nonstop1h 25m
Deal found 8/5![Southwest logo]()
$254
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/611:00 am -
1 stop6h 23m
Mon 9/77:05 am -
1 stop5h 41m
Deal found 8/5![Delta logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/302:29 pm -
1 stop27h 26m
Wed 10/74:30 pm -
2 stops18h 10m
Deal found 8/3![Frontier logo]()
$167
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:40 pm -
Nonstop1h 25m
Wed 10/76:50 am -
Nonstop1h 25m
Deal found 8/3![Southwest logo]()
$257
One-way flights from St. Louis to ColumbusSearch for one-way flight options from St. Louis to Columbus. Find affordable one-way fares based on user searches. Data last updated August 7, 2026.
Search for one-way flight options from St. Louis to Columbus. Find affordable one-way fares based on user searches. Data last updated August 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/810:35 am -
1 stop5h 58m
Deal found 8/7![Frontier logo]()
$53
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:17 pm -
1 stop22h 08m
Deal found 8/5![Frontier logo]()
$58
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/52:29 pm -
1 stop27h 26m
Deal found 8/3![Frontier logo]()
$59
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/302:29 pm -
1 stop27h 26m
Deal found 8/3![Frontier logo]()
$68
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/410:35 am -
1 stop28h 04m
Deal found 8/3![Frontier logo]()
$69
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3110:35 am -
1 stop29h 04m
Deal found 8/3![Frontier logo]()
$74
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:17 pm -
1 stop22h 08m
Deal found 8/4![Frontier logo]()
$75
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/210:35 am -
1 stop28h 04m
Deal found 8/3![Frontier logo]()
$95
This Trip.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/55:02 pm -
1 stop25h 42m
Deal found 8/6![Frontier logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/282:29 pm -
2 stops29h 02m
Deal found 8/6![Frontier logo]()
$104
Find flight deals from St. Louis to Columbus
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Columbus (C01). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 7, 2026.
Round-trip from | $105 (Kiwi.com) |
|---|---|
One-way from | $53 (Kiwi.com) |
Popular in | February |
Cheapest in | January |
Average price | $399 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Columbus that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 7, 2026.
Use the filters below to find and compare flights from St. Louis to Columbus that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisColumbus
STL Lambert-St Louis - CMH Columbus
STLCMH
Lambert-St Louis
Wed 9/9
1:40 pm-8:04 pm
1 stop5h 24m
Columbus
Fri 9/11
6:00 am-9:34 am
1 stop4h 34m
$269
St. LouisColumbus
STL Lambert-St Louis - CMH Columbus
STLCMH
Lambert-St Louis
Wed 9/30
7:15 am-12:45 pm
1 stop4h 30m
Columbus
Wed 9/30
1:45 pm-8:00 pm
1 stop7h 15m
$277
Quickest round-trip
St. LouisColumbus
STL Lambert-St Louis - CMH Columbus
STLCMH
Lambert-St Louis
Fri 9/4
6:50 pm-9:15 pm
Nonstop1h 25m
Columbus
Fri 9/11
7:20 am-7:45 am
Nonstop1h 25m
$281
St. LouisColumbus
STL Lambert-St Louis - CMH Columbus
STLCMH
Lambert-St Louis
Sun 9/6
5:50 pm-8:10 pm
Nonstop1h 20m
Columbus
Sun 9/13
11:20 am-2:30 pm
1 stop4h 10m
$286
St. LouisColumbus
STL Lambert-St Louis - CMH Columbus
STLCMH
Lambert-St Louis
Fri 9/4
5:23 pm-12:58 am
1 stop6h 35m
Columbus
Sat 9/5
6:00 am-9:20 am
1 stop4h 20m
$296
St. LouisColumbus
STL Lambert-St Louis - CMH Columbus
STLCMH
Lambert-St Louis
Mon 11/16
12:40 pm-6:10 pm
1 stop4h 30m
Columbus
Mon 11/23
3:00 pm-9:00 pm
2 stops7h 00m
$296
St. LouisColumbus
STL Lambert-St Louis - CMH Columbus
STLCMH
Lambert-St Louis
Fri 10/23
2:00 pm-6:25 pm
1 stop3h 25m
Columbus
Sun 10/25
7:10 am-7:35 am
Nonstop1h 25m
$297
St. LouisColumbus
STL Lambert-St Louis - CMH Columbus
STLCMH
Lambert-St Louis
Thu 9/24
6:50 pm-9:15 pm
Nonstop1h 25m
Columbus
Fri 9/25
1:40 pm-4:45 pm
1 stop4h 05m
$303
St. LouisColumbus
STL Lambert-St Louis - CMH Columbus
STLCMH
Lambert-St Louis
Wed 9/16
10:05 am-6:10 pm
1 stop7h 05m
Columbus
Fri 9/18
6:00 am-9:00 am
1 stop4h 00m
$308
St. LouisColumbus
STL Lambert-St Louis - CMH Columbus
STLCMH
Lambert-St Louis
Tue 8/18
9:15 am-5:27 pm
1 stop7h 12m
Columbus
Sat 8/22
7:08 am-11:56 am
1 stop5h 48m
$335
Showing 1-10 of 22 resultsSorted by cheapest first
Best time to book a flight from St. Louis to Columbus
Have a flexible travel schedule? Discover the best time to fly to Columbus from St. Louis with our price prediction graph.
STL-C01
STL-CMH
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Columbus
STL-C01
STL-CMH
What is the cheapest month to book a flight from St. Louis to Columbus?
Currently, January is the cheapest month in which you can book a flight from St. Louis to Columbus (average of $332). Flying from St. Louis to Columbus in February is currently the most expensive (average of $621). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from STL to CMH?
Find hourly flight availability from St. Louis to Columbus. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 7, 2026.
It’s optimal to fly from St. Louis to Columbus in the evening. By choosing this option you can save up to 45% on the cost of your flight, compared to a flight in the afternoon.
How much does it cost to fly round-trip from St. Louis to Columbus?
Airfare is below average for this route at the moment.
St. Louis to Columbus flights typically cost between $319 and $653 in October.The cheapest round-trip price found within the last 5 days was $105 on Frontier (Oct 8-Oct 11).
Reviews of airlines servicing Columbus
Get insights into the airlines that provide service to Columbus. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Columbus. Reviews last updated August 7, 2026.
See what other customers who have flown with Southwest from St. Louis to Columbus have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.6
Food
7.0
Overall
8.0
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Boarding
8.1
Crew
8.6
Food
7.0
Overall
8.0
Entertainment
7.5
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Columbus. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for St. Louis to Columbus
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Complete your trip
Complete your trip to Columbus by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from St. Louis to Columbus by cabin class
Find flights from St. Louis to Columbus, based on your preferred cabin class, be it economy, premium economy, business, or first class.
St. Louis and Columbus flights
Browse other St. Louis and Columbus flight options. Last updated on August 7, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on August 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from St. Louis to Columbus
Discover the top 3 airlines that operate flights from St. Louis to Columbus. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$229 | Average$370 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$248 | Average$360 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$288 | Average$318 | FlexibilityNo cancel fee | On-time71% |