$344+ Cheap flights from Myrtle Beach to Columbia, MO (MYR - COU)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/25. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — COU
Oct 14 — Oct 211
Round-trip
1 adult, Economy
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Find cheap flights from Myrtle Beach to Columbia with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Myrtle Beach to Columbia
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Best
Last-minute
Cheapest flights from Myrtle Beach to ColumbiaExplore the most affordable flight options available from Myrtle Beach to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2026.
Explore the most affordable flight options available from Myrtle Beach to Columbia. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 14, 2026.
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:00 pm -
1 stop6h 55m
Tue 9/296:15 am -
2 stops10h 57m
Deal found 9/10![United Airlines logo]()
$344
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:45 pm -
1 stop5h 23m
Wed 9/3010:38 am -
2 stops7h 11m
Deal found 9/11![American Airlines logo]()
$496
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:45 pm -
1 stop5h 23m
Tue 9/298:16 am -
1 stop4h 10m
Deal found 9/10![American Airlines logo]()
$558
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/198:08 am -
2 stops10h 54m
Mon 9/215:44 am -
2 stops10h 11m
Deal found 9/13![American Airlines logo]()
$634
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:45 pm -
1 stop5h 23m
Mon 9/215:44 am -
2 stops10h 11m
Deal found 9/13![American Airlines logo]()
$635
Best flights from Myrtle Beach to ColumbiaDiscover carefully curated flight deals from Myrtle Beach to Columbia that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 14, 2026.
Discover carefully curated flight deals from Myrtle Beach to Columbia that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 14, 2026.
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:00 pm -
1 stop6h 55m
Tue 9/296:15 am -
2 stops10h 57m
Deal found 9/10![United Airlines logo]()
$344
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:45 pm -
1 stop5h 23m
Tue 9/298:16 am -
1 stop4h 10m
Deal found 9/10![American Airlines logo]()
$558
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2612:10 pm -
2 stops8h 13m
Wed 9/3010:38 am -
2 stops7h 11m
Deal found 9/11![American Airlines logo]()
$586
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2612:30 pm -
2 stops11h 25m
Wed 9/306:15 am -
3 stops10h 57m
Deal found 9/11![United Airlines logo]()
$878
Last-minute flights from Myrtle Beach to ColumbiaDiscover last-minute flight deals from Myrtle Beach to Columbia. Data last updated September 14, 2026 and is based on user searches.
Discover last-minute flight deals from Myrtle Beach to Columbia. Data last updated September 14, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:45 pm -
1 stop5h 23m
Mon 9/215:44 am -
2 stops10h 11m
Deal found 9/13![American Airlines logo]()
$635
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/198:08 am -
2 stops10h 54m
Mon 9/215:44 am -
2 stops10h 11m
Deal found 9/13![American Airlines logo]()
$634
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:00 pm -
1 stop6h 55m
Tue 9/296:15 am -
2 stops10h 57m
Deal found 9/10![United Airlines logo]()
$344
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:45 pm -
1 stop5h 23m
Tue 9/298:16 am -
1 stop4h 10m
Deal found 9/10![American Airlines logo]()
$558
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:45 pm -
1 stop5h 23m
Wed 9/3010:38 am -
2 stops7h 11m
Deal found 9/11![American Airlines logo]()
$496
Find flight deals from Myrtle Beach to Columbia
Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to Columbia (COU). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 14, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $344 (United Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to Columbia that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 14, 2026.
Use the filters below to find and compare flights from Myrtle Beach to Columbia that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Myrtle BeachColumbia
MYR Myrtle Beach Intl - COU Columbia Regional
MYRCOU
Myrtle Beach Intl
Fri 9/25
5:00 pm-10:55 pm
1 stop6h 55m
Columbia Regional
Tue 9/29
6:15 am-6:12 pm
2 stops10h 57m
$344
Quickest round-trip
Myrtle BeachColumbia
MYR Myrtle Beach Intl - COU Columbia Regional
MYRCOU
Myrtle Beach Intl
Fri 9/25
5:45 pm-10:08 pm
1 stop5h 23m
Columbia Regional
Tue 9/29
8:16 am-1:26 pm
1 stop4h 10m
$558
Myrtle BeachColumbia
MYR Myrtle Beach Intl - COU Columbia Regional
MYRCOU
Myrtle Beach Intl
Sat 9/26
12:10 pm-7:23 pm
2 stops8h 13m
Columbia Regional
Wed 9/30
10:38 am-6:49 pm
2 stops7h 11m
$586
Myrtle BeachColumbia
MYR Myrtle Beach Intl - COU Columbia Regional
MYRCOU
Myrtle Beach Intl
Sat 9/26
12:30 pm-10:55 pm
2 stops11h 25m
Columbia Regional
Wed 9/30
6:15 am-6:12 pm
3 stops10h 57m
$878
Sorted by cheapest first
Compare providers for flights from Myrtle Beach to Columbia
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to Columbia in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Myrtle Beach-Columbia, Missouri flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-Columbia, Missouri flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-Columbia, Missouri flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Myrtle Beach-Columbia, Missouri flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-Columbia, Missouri flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Myrtle Beach to Columbia
Have a flexible travel schedule? Discover the best time to fly to Columbia from Myrtle Beach with our price prediction graph.
MYR-COU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to Columbia. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Columbia?
Book flights to Columbia if you plan to visit one of these locationsJefferson City
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