$500+ Cheap flights from Panama City (PTY) to Cleveland (CLE)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/12. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CLE
Oct 7 — Oct 141
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to Cleveland with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to Cleveland
Cheapest
Best
Last-minute
One-way
Cheapest flights from Panama City to ClevelandExplore the most affordable flight options available from Panama City to Cleveland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
Explore the most affordable flight options available from Panama City to Cleveland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 7, 2026.
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/144:41 pm -
1 stop29h 17m
Mon 1/186:00 pm -
1 stop25h 38m
Deal found 9/5![United Airlines logo]()
$604
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/143:13 pm -
2 stops24h 11m
Mon 1/186:42 pm -
1 stop18h 54m
Deal found 9/5![American Airlines logo]()
$663
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/162:02 pm -
1 stop8h 57m
Tue 10/276:00 am -
1 stop8h 02m
Deal found 9/7![American Airlines logo]()
$680
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/293:30 pm -
1 stop29h 52m
Tue 10/134:07 pm -
1 stop28h 24m
Deal found 9/4![United Airlines logo]()
$714
This American Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/291:16 pm -
1 stop9h 30m
Tue 10/136:43 pm -
2 stops19h 19m
Deal found 9/4![American Airlines logo]()
$727
Best flights from Panama City to ClevelandDiscover carefully curated flight deals from Panama City to Cleveland that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
Discover carefully curated flight deals from Panama City to Cleveland that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 7, 2026.
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/144:41 pm -
1 stop29h 17m
Mon 1/186:00 pm -
1 stop25h 38m
Deal found 9/5![United Airlines logo]()
$604
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/162:02 pm -
1 stop8h 57m
Tue 10/276:00 am -
1 stop8h 02m
Deal found 9/7![American Airlines logo]()
$680
This Delta deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/292:23 pm -
1 stop9h 16m
Tue 10/136:00 am -
1 stop7h 59m
Deal found 9/5![Delta logo]()
$714
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2910:00 am -
1 stop9h 52m
Tue 10/136:00 am -
2 stops15h 31m
Deal found 9/4![Multiple Airlines logo]()
$727
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/293:30 pm -
1 stop29h 52m
Tue 10/134:07 pm -
1 stop28h 24m
Deal found 9/4![United Airlines logo]()
$714
Last-minute flights from Panama City to ClevelandDiscover last-minute flight deals from Panama City to Cleveland. Data last updated September 7, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Cleveland. Data last updated September 7, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/162:23 pm -
1 stop9h 16m
Wed 9/237:05 am -
1 stop6h 53m
Deal found 9/6![Delta logo]()
$746
This United Airlines deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/293:30 pm -
1 stop29h 52m
Tue 10/134:07 pm -
1 stop28h 24m
Deal found 9/4![United Airlines logo]()
$714
This Kiwi.com deal was found by Cheapflights users on 9/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2910:00 am -
1 stop9h 52m
Tue 10/136:00 am -
2 stops15h 31m
Deal found 9/4![Multiple Airlines logo]()
$727
This American Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/291:16 pm -
1 stop9h 30m
Tue 10/136:43 pm -
2 stops19h 19m
Deal found 9/5![American Airlines logo]()
$741
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/13:30 pm -
1 stop19h 01m
Mon 10/57:00 am -
1 stop13h 31m
Deal found 9/6![United Airlines logo]()
$755
This American Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/162:02 pm -
1 stop8h 57m
Tue 10/276:00 am -
1 stop8h 02m
Deal found 9/7![American Airlines logo]()
$680
One-way flights from Panama City to ClevelandSearch for one-way flight options from Panama City to Cleveland. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
Search for one-way flight options from Panama City to Cleveland. Find affordable one-way fares based on user searches. Data last updated September 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1210:00 am -
1 stop25h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Multiple Airlines logo]()
$500
This FlightHub deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1211:25 am -
3 stops21h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Avianca logo]()
$533
Find flight deals from Panama City to Cleveland
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Cleveland (CLE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $604 (United Airlines) |
One-way from | $500 (Kiwi.com) |
Popular in | March |
Cheapest in | February |
Average price | $738 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Cleveland that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
Use the filters below to find and compare flights from Panama City to Cleveland that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityCleveland
PTY Panama City Tocumen Intl - CLE Cleveland Hopkins Intl
PTYCLE
Panama City Tocumen Intl
Sat 9/12
10:00 am-12:22 pm
1 stop25h 22m
Cleveland Hopkins Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$500
Panama CityCleveland
PTY Panama City Tocumen Intl - CLE Cleveland Hopkins Intl
PTYCLE
Panama City Tocumen Intl
Sat 9/12
11:25 am-9:35 am
3 stops21h 10m
Cleveland Hopkins Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$533
Panama CityCleveland
PTY Panama City Tocumen Intl - CLE Cleveland Hopkins Intl
PTYCLE
Panama City Tocumen Intl
Mon 12/14
4:41 pm-9:58 pm
1 stop29h 17m
Cleveland Hopkins Intl
Mon 1/18
6:00 pm-7:38 pm
1 stop25h 38m
$604
Quickest round-trip
Panama CityCleveland
PTY Panama City Tocumen Intl - CLE Cleveland Hopkins Intl
PTYCLE
Panama City Tocumen Intl
Fri 10/16
2:02 pm-11:59 pm
1 stop8h 57m
Cleveland Hopkins Intl
Tue 10/27
6:00 am-1:02 pm
1 stop8h 02m
$680
Panama CityCleveland
PTY Panama City Tocumen Intl - CLE Cleveland Hopkins Intl
PTYCLE
Panama City Tocumen Intl
Tue 9/29
2:23 pm-12:39 am
1 stop9h 16m
Cleveland Hopkins Intl
Tue 10/13
6:00 am-12:59 pm
1 stop7h 59m
$714
Panama CityCleveland
PTY Panama City Tocumen Intl - CLE Cleveland Hopkins Intl
PTYCLE
Panama City Tocumen Intl
Tue 9/29
3:30 pm-10:22 pm
1 stop29h 52m
Cleveland Hopkins Intl
Tue 10/13
4:07 pm-7:31 pm
1 stop28h 24m
$714
Panama CityCleveland
PTY Panama City Tocumen Intl - CLE Cleveland Hopkins Intl
PTYCLE
Panama City Tocumen Intl
Tue 9/29
10:00 am-8:52 pm
1 stop9h 52m
Cleveland Hopkins Intl
Tue 10/13
6:00 am-8:31 pm
2 stops15h 31m
$727
Sorted by cheapest first
Compare providers for flights from Panama City to Cleveland
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Cleveland in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City-Cleveland flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Cleveland flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Cleveland flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City-Cleveland flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Cleveland flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to Cleveland
Have a flexible travel schedule? Discover the best time to fly to Cleveland from Panama City with our price prediction graph.
PTY-CLE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Cleveland
Reviews of airlines servicing Cleveland
Get insights into the airlines that provide service to Cleveland. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cleveland. Reviews last updated September 7, 2026.
Read through reviews of airlines operating flights from Panama City to Cleveland, such as United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.1
Comfort
7.3
Food
6.6
Crew
8.1
Overall
7.4
Boarding
7.7
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Entertainment
7.1
Comfort
7.3
Food
6.6
Crew
8.1
Overall
7.4
Boarding
7.7
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Related info for your journey
Find useful and relevant information for your journey from Panama City to Cleveland. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Cleveland?
Book flights to Cleveland if you plan to visit one of these locationsSandusky
Beachwood
Independence
Mansfield
Strongsville
Lakewood
Avon
Streetsboro
Medina
North Olmsted
Cuyahoga Falls
Kent
Westlake
Elyria
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Explore flights to Cleveland departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 7, 2026.
Complete your trip
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Panama City and Cleveland flights
Browse other Panama City and Cleveland flight options. Last updated on September 7, 2026.
Other flights from Panama City
Browse through other flights departing from Panama City. Flights are based on user searches made on Cheapflights and were last updated on September 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Panama City to Cleveland
Discover the top airline that operate flights from Panama City to Cleveland. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$644 | Average$718 | FlexibilityNo cancel fee | On-time69% |