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$278+ Cheap flights from Panama City (PTY) to Cleveland (CLE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/14. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CLE
Dec 19 — Dec 261
Fri 12/19
Fri 12/26
1 adult, Economy
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Find flight deals from Panama City to Cleveland

Cheapest flights from Panama City to Cleveland
Explore the most affordable flight options available from Panama City to Cleveland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 19, 2025.

This United Airlines deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/154:41 pmPTY - CLE
1 stop18h 27mUnited Airlines
Wed 4/156:09 pmCLE - PTY
1 stop25h 28mUnited Airlines
Deal found 11/17$526
This American Airlines deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/154:43 pmPTY - CLE
1 stop23h 55mAmerican Airlines
Wed 4/157:01 pmCLE - PTY
2 stops18h 14mAmerican Airlines
Deal found 11/17$575
This American Airlines deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/262:53 pmPTY - CLE
1 stop9h 06mAmerican Airlines
Sun 1/46:00 amCLE - PTY
1 stop7h 53mAmerican Airlines
Deal found 11/17$578
This Delta deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/43:46 pmPTY - CLE
1 stop8h 51mDelta
Mon 12/86:05 amCLE - PTY
1 stop8h 16mDelta
Deal found 11/16$600
This American Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/44:43 pmPTY - CLE
2 stops19h 07mAmerican Airlines
Mon 12/87:36 pmCLE - PTY
2 stops18h 11mAmerican Airlines
Deal found 11/18$722
This Kiwi.com deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:55 amPTY - CLE
2 stops15h 25mMultiple Airlines
Thu 1/84:04 pmCLE - PTY
1 stop28h 15mMultiple Airlines
Deal found 11/16$924
This Mytrip deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/269:45 amPTY - CLE
3 stops24h 52mMultiple Airlines
Sun 1/411:43 amCLE - PTY
3 stops36h 57mMultiple Airlines
Deal found 11/17$998
This Expedia deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/142:55 amPTY - CLE
2 stops16h 02mAvianca
Wed 4/156:00 amCLE - PTY
2 stops33h 45mAvianca
Deal found 11/17$1,034
This Mytrip deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/142:55 amPTY - CLE
3 stops35h 19mMultiple Airlines
Wed 4/156:15 pmCLE - PTY
2 stops15h 40mMultiple Airlines
Deal found 11/17$1,333

Cheap flight deals from Panama City to Cleveland

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Cleveland (CLE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 19, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$526
(United Airlines)

One-way from

$278
(Kiwi.com)

Popular in

April

Cheapest in

January

Average price

$680
Provider with most accurate pricing for Panama City Tocumen Intl-Cleveland Hopkins Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Cleveland Hopkins Intl flights.
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From Panama City Tocumen Intl to Cleveland Hopkins Intl
Search Deals
One-way flight from Panama City Tocumen Intl to Cleveland Hopkins Intl
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($72 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Cleveland that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 19, 2025.
Use the filters below to find and compare flights from Panama City to Cleveland that are best for you.

Fly from

Panama City

Fly to

Cleveland

Route

Depart

Return

Price

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Mon 12/15

4:41 pm-11:08 am

1 stop18h 27m

Cleveland Hopkins Intl

Wed 4/15

6:09 pm-6:37 pm

1 stop25h 28m

$526

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Mon 12/15

4:43 pm-4:38 pm

1 stop23h 55m

Cleveland Hopkins Intl

Wed 4/15

7:01 pm-12:15 pm

2 stops18h 14m

$575

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Fri 12/26

2:53 pm-9:59 am

2 stops19h 06m

Cleveland Hopkins Intl

Sun 1/4

6:36 pm-1:53 pm

2 stops19h 17m

$583

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Thu 12/4

3:46 pm-12:37 am

1 stop8h 51m

Cleveland Hopkins Intl

Mon 12/8

6:05 am-2:21 pm

1 stop8h 16m

$600

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Thu 12/4

8:55 am-9:50 pm

1 stop12h 55m

Cleveland Hopkins Intl

Mon 12/8

6:03 am-2:45 pm

1 stop8h 42m

$600

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Thu 1/1

11:55 pm-9:47 am

1 stop9h 52m

Cleveland Hopkins Intl

Thu 1/8

6:00 am-5:07 pm

1 stop11h 07m

$681

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Thu 12/4

4:43 pm-9:58 am

2 stops17h 15m

Cleveland Hopkins Intl

Mon 12/8

7:36 pm-1:47 pm

2 stops18h 11m

$722

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Wed 1/14

5:50 pm-12:19 am

3 stops30h 29m

$278

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Fri 12/12

11:25 am-10:13 pm

2 stops10h 48m

$283

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Wed 1/14

4:41 pm-11:08 am

1 stop18h 27m

$307

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/17

Showing 1-10 of 16 results
1
2

Compare providers for flights from Panama City to Cleveland

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Cleveland in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City-Cleveland flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Panama City-Cleveland flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Panama City-Cleveland flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Cleveland flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Cleveland flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Cleveland

Have a flexible travel schedule? Discover the best time to fly to Cleveland from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Cleveland

What is the cheapest month to book a flight from Panama City to Cleveland?

Currently, December is the cheapest month in which you can book a flight from Panama City to Cleveland (average of $336). Flying from Panama City to Cleveland in March is currently the most expensive (average of $718). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to CLE?

Find hourly flight availability from Panama City to Cleveland. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 19, 2025.

When flying from Panama City to Cleveland, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 11% versus a flight in the morning.

Reviews of airlines servicing Cleveland

Get insights into the airlines that provide service to Cleveland. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cleveland. Reviews last updated November 19, 2025.
Read through reviews of airlines operating flights from Panama City to Cleveland, such as Delta and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,004 reviews

Crew

8.5

Boarding

8.1

Comfort

7.9

Overall

7.9

Entertainment

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,004 reviews
Delta
7.9
Good
8,004 reviews

Crew

8.5

Boarding

8.1

Comfort

7.9

Overall

7.9

Entertainment

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,023 reviews
Delta
7.9
Good
8,004 reviews

Crew

8.5

Boarding

8.1

Comfort

7.9

Overall

7.9

Entertainment

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Cleveland. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City to Cleveland?

    United Airlines and American Airlines can get you from Panama City to Cleveland in just under 18h 27m. Your travel time can differ by up to 5h 28m. The distance from Panama City to Cleveland is about 2238 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Panama City to Cleveland round-trip?

    Currently priced at $483, Delta will fly you from Panama City to Cleveland and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on United Airlines for as low as $580. Delta is priced at 24% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Panama City to Cleveland that include hotel bookings?

    Yes. In addition to deals on Panama City to Cleveland flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Cleveland?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Cleveland.

  • Can I find deals for business class flights from Panama City to Cleveland?

    Yes. Cheapflights offers flight deals from Panama City to Cleveland by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Cleveland?

    Currently, December is the cheapest month in which you can book a flight from Panama City to Cleveland (average of $336). Flying from Panama City to Cleveland in March is currently the most expensive (average of $718). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Cleveland?

Book flights to Cleveland if you plan to visit one of these locations
Sandusky
Mentor
Mansfield
Avon
Beachwood
Wooster
Independence
Willoughby
Elyria
Streetsboro
Cleveland Heights
North Olmsted
Cuyahoga Falls
Macedonia
Kent
Strongsville
Medina
Lakewood
Westlake

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama City to Cleveland

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Panama City to Cleveland

Discover the top 2 airlines that operate flights from Panama City to Cleveland. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 19, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$483Average$670FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$580Average$644FlexibilityNo cancel feeOn-time69%

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