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$270+ Cheap flights from Panama City (PTY) to Cleveland (CLE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/2. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CLE
May 11 — May 181
Mon 5/11
Mon 5/18
1 adult, Economy
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Cheap flight deals from Panama City to Cleveland

Cheapest flights from Panama City to Cleveland
Explore the most affordable flight options available from Panama City to Cleveland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 11, 2026.

This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1012:23 pm
PTY
-
CLE
1 stop10h 20m
Multiple Airlines
Mon 6/154:36 pm
CLE
-
PTY
1 stop16h 30m
Multiple Airlines
Deal found 4/8$541
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1012:23 pm
PTY
-
CLE
1 stop10h 20m
Multiple Airlines
Sun 6/146:40 am
CLE
-
PTY
2 stops14h 57m
Multiple Airlines
Deal found 4/8$610
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:35 pm
PTY
-
CLE
1 stop7h 39m
American Airlines
Tue 10/276:28 am
CLE
-
PTY
1 stop8h 32m
American Airlines
Deal found 4/6$622
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/910:25 am
PTY
-
CLE
1 stop12h 18m
Multiple Airlines
Wed 6/174:36 pm
CLE
-
PTY
1 stop16h 54m
Multiple Airlines
Deal found 4/8$623
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/410:26 am
PTY
-
CLE
1 stop8h 08m
Multiple Airlines
Mon 6/154:36 pm
CLE
-
PTY
2 stops17h 39m
Multiple Airlines
Deal found 4/8$624
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1012:23 pm
PTY
-
CLE
1 stop10h 20m
Multiple Airlines
Wed 6/174:36 pm
CLE
-
PTY
1 stop16h 30m
Multiple Airlines
Deal found 4/8$625
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1012:23 pm
PTY
-
CLE
1 stop10h 20m
Multiple Airlines
Thu 6/184:36 pm
CLE
-
PTY
1 stop16h 54m
Multiple Airlines
Deal found 4/8$628
This American Airlines deal was found by Cheapflights users on 4/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/281:14 pm
PTY
-
CLE
1 stop9h 39m
American Airlines
Tue 8/257:11 pm
CLE
-
PTY
1 stop20h 09m
American Airlines
Deal found 4/10$634
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/912:23 pm
PTY
-
CLE
1 stop10h 20m
Multiple Airlines
Thu 6/184:36 pm
CLE
-
PTY
1 stop16h 54m
Multiple Airlines
Deal found 4/8$637
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/610:26 am
PTY
-
CLE
1 stop9h 28m
Multiple Airlines
Tue 6/164:36 pm
CLE
-
PTY
1 stop16h 30m
Multiple Airlines
Deal found 4/8$638
This Delta deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/42:15 pm
PTY
-
CLE
1 stop18h 02m
Delta
Tue 6/167:05 am
CLE
-
PTY
1 stop7h 04m
Delta
Deal found 4/8$643

Find flight deals from Panama City to Cleveland

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Cleveland (CLE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 11, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$541
(Kiwi.com)

One-way from

$270
(Kiwi.com)

Popular in

March

Cheapest in

November

Average price

$802
Provider with most accurate pricing for Panama City Tocumen Intl-Cleveland Hopkins Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Cleveland Hopkins Intl flights.
Search Deals
From Panama City Tocumen Intl to Cleveland Hopkins Intl
Search Deals
One-way flight from Panama City Tocumen Intl to Cleveland Hopkins Intl
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($69 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($21 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Cleveland that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 11, 2026.
Use the filters below to find and compare flights from Panama City to Cleveland that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Tue 7/28

1:14 pm-11:53 pm

1 stop9h 39m

Cleveland Hopkins Intl

Tue 8/25

7:11 pm-2:20 pm

1 stop20h 09m

$634

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Wed 6/10

2:24 pm-9:24 am

1 stop18h 00m

Cleveland Hopkins Intl

Tue 6/16

7:05 am-1:09 pm

1 stop7h 04m

$643

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Sun 6/7

7:55 am-9:59 pm

1 stop13h 04m

Cleveland Hopkins Intl

Sun 6/14

7:08 pm-4:04 am

1 stop9h 56m

$685
Quickest round-trip

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Sat 6/6

7:55 am-6:30 pm

1 stop9h 35m

Cleveland Hopkins Intl

Sun 6/14

7:08 pm-4:04 am

1 stop9h 56m

$685

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Thu 5/14

3:30 pm-9:55 pm

1 stop29h 25m

Cleveland Hopkins Intl

Sat 5/23

7:11 pm-4:04 am

1 stop9h 53m

$688

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Thu 4/23

10:55 pm-10:14 am

1 stop10h 19m

Cleveland Hopkins Intl

Mon 4/27

6:00 am-2:14 pm

1 stop9h 14m

$740
Cheapest one-way

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Sat 5/2

3:10 pm-9:18 am

2 stops17h 08m

$270

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Sun 5/3

10:10 am-8:53 am

3 stops45h 43m

$292

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Sun 4/19

5:55 pm-3:36 pm

2 stops44h 41m

$307

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Sat 4/18

5:55 pm-8:40 pm

3 stops49h 45m

$321

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/8

Showing 1-10 of 14 resultsSorted by cheapest first
1
2

Compare providers for flights from Panama City to Cleveland

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Cleveland in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City-Cleveland flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Cleveland flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Cleveland flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Cleveland flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Cleveland flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Cleveland

Have a flexible travel schedule? Discover the best time to fly to Cleveland from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Cleveland

What is the cheapest month to book a flight from Panama City to Cleveland?

Currently, November is the cheapest month in which you can book a flight from Panama City to Cleveland (average of $504). Flying from Panama City to Cleveland in March is currently the most expensive (average of $836). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Panama City to Cleveland?

Reviews of airlines servicing Cleveland

Get insights into the airlines that provide service to Cleveland. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cleveland. Reviews last updated April 11, 2026.
Read through reviews of airlines operating flights from Panama City to Cleveland, such as Delta and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,406 reviews

Boarding

8.1

Overall

7.9

Entertainment

7.8

Food

7.2

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,406 reviews
Delta
7.9
Good
8,406 reviews

Boarding

8.1

Overall

7.9

Entertainment

7.8

Food

7.2

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,569 reviews
Delta
7.9
Good
8,406 reviews

Boarding

8.1

Overall

7.9

Entertainment

7.8

Food

7.2

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Cleveland. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Panama City to Cleveland round-trip?

    Currently priced at $504, Delta will fly you from Panama City to Cleveland and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Check Cheapflights for deals on United Airlines for as low as $613. Delta is priced at 25% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Panama City to Cleveland that include hotel bookings?

    Yes. In addition to deals on Panama City to Cleveland flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Cleveland?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Cleveland.

  • Can I find deals for business class flights from Panama City to Cleveland?

    Yes. Cheapflights offers flight deals from Panama City to Cleveland by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Cleveland?

    Currently, November is the cheapest month in which you can book a flight from Panama City to Cleveland (average of $504). Flying from Panama City to Cleveland in March is currently the most expensive (average of $836). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Cleveland?

Book flights to Cleveland if you plan to visit one of these locations
Sandusky
Mentor
Avon
Mansfield
Beachwood
Wooster
Independence
Strongsville
Lakewood
Streetsboro
Medina
North Olmsted
Cuyahoga Falls
Cleveland Heights
Macedonia
Kent
Elyria

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama City to Cleveland

See prices for flight routes from nearby airports that may be better suited for you.
Panama City to Pittsburgh flights
Panama City to Cincinnati flights

Top 2 airlines flying from Panama City to Cleveland

Discover the top 2 airlines that operate flights from Panama City to Cleveland. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 11, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$504Average$718FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$613Average$802FlexibilityNo cancel feeOn-time69%

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