$452+ Cheap flights from Panama City (PTY) to Cleveland (CLE)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/20. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CLE
Dec 5 — Dec 121
Round-trip
1 adult, Economy
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Find cheap flights from Panama City to Cleveland with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Panama City to Cleveland
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Best
Last-minute
One-way
Cheapest flights from Panama City to ClevelandExplore the most affordable flight options available from Panama City to Cleveland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
Explore the most affordable flight options available from Panama City to Cleveland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/184:41 pm -
1 stop29h 34m
Fri 12/255:59 pm -
1 stop25h 39m
Deal found 11/3![United Airlines logo]()
$838
This Mytrip deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/185:30 am -
2 stops17h 46m
Fri 12/255:01 pm -
2 stops32h 19m
Deal found 11/3![Multiple Airlines logo]()
$1,014
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/184:33 pm -
2 stops18h 17m
Fri 12/253:31 pm -
2 stops24h 02m
Deal found 11/2![American Airlines logo]()
$1,233
Best flights from Panama City to ClevelandDiscover carefully curated flight deals from Panama City to Cleveland that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
Discover carefully curated flight deals from Panama City to Cleveland that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/284:41 pm -
1 stop25h 43m
Sun 1/311:00 pm -
1 stop31h 02m
Deal found 11/2![United Airlines logo]()
$699
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1812:10 pm -
2 stops22h 31m
Fri 12/257:45 pm -
1 stop13h 35m
Deal found 11/3![Multiple Airlines logo]()
$1,060
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/184:33 pm -
2 stops18h 17m
Fri 12/253:31 pm -
2 stops24h 02m
Deal found 11/2![American Airlines logo]()
$1,233
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/264:41 pm -
1 stop18h 54m
Sat 1/306:00 am -
1 stop11h 12m
Deal found 10/30![United Airlines logo]()
$710
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/184:41 pm -
1 stop29h 34m
Fri 12/255:59 pm -
1 stop25h 39m
Deal found 11/3![United Airlines logo]()
$838
Last-minute flights from Panama City to ClevelandDiscover last-minute flight deals from Panama City to Cleveland. Data last updated November 5, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Cleveland. Data last updated November 5, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/184:41 pm -
1 stop29h 34m
Fri 12/255:59 pm -
1 stop25h 39m
Deal found 11/3![United Airlines logo]()
$838
This Mytrip deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/185:30 am -
2 stops17h 46m
Fri 12/255:01 pm -
2 stops32h 19m
Deal found 11/3![Multiple Airlines logo]()
$1,014
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/184:33 pm -
2 stops18h 17m
Fri 12/253:31 pm -
2 stops24h 02m
Deal found 11/2![American Airlines logo]()
$1,233
One-way flights from Panama City to ClevelandSearch for one-way flight options from Panama City to Cleveland. Find affordable one-way fares based on user searches. Data last updated November 5, 2026.
Search for one-way flight options from Panama City to Cleveland. Find affordable one-way fares based on user searches. Data last updated November 5, 2026.
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2011:35 am -
1 stop23h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![United Airlines logo]()
$452
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/68:00 am -
1 stop12h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Delta logo]()
$463
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/59:31 pm -
2 stops45h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Multiple Airlines logo]()
$466
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/204:33 pm -
2 stops21h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![American Airlines logo]()
$467
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/48:00 am -
1 stop26h 02m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Delta logo]()
$508
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/209:26 pm -
3 stops50h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Multiple Airlines logo]()
$530
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/44:33 pm -
2 stops18h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![American Airlines logo]()
$686
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/52:41 pm -
2 stops24h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![American Airlines logo]()
$691
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/58:00 am -
1 stop7h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Delta logo]()
$717
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/46:36 pm -
3 stops48h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Multiple Airlines logo]()
$765
Find flight deals from Panama City to Cleveland
Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Cleveland (CLE). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $690 (Delta) |
One-way from | $452 (United Airlines) |
Popular in | March |
Cheapest in | February |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Cleveland that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
Use the filters below to find and compare flights from Panama City to Cleveland that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Panama CityCleveland
PTY Panama City Tocumen Intl - CLE Cleveland Hopkins Intl
PTYCLE
Panama City Tocumen Intl
Sun 12/20
11:35 am-11:16 am
1 stop23h 41m
Cleveland Hopkins Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$452
Panama CityCleveland
PTY Panama City Tocumen Intl - CLE Cleveland Hopkins Intl
PTYCLE
Panama City Tocumen Intl
Mon 1/4
8:00 am-10:02 am
1 stop26h 02m
Cleveland Hopkins Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$508
Panama CityCleveland
PTY Panama City Tocumen Intl - CLE Cleveland Hopkins Intl
PTYCLE
Panama City Tocumen Intl
Thu 1/28
4:41 pm-6:24 pm
1 stop25h 43m
Cleveland Hopkins Intl
Sun 1/31
1:00 pm-8:02 pm
1 stop31h 02m
$699
Panama CityCleveland
PTY Panama City Tocumen Intl - CLE Cleveland Hopkins Intl
PTYCLE
Panama City Tocumen Intl
Mon 1/4
2:41 pm-5:59 pm
1 stop27h 18m
Cleveland Hopkins Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$706
Panama CityCleveland
PTY Panama City Tocumen Intl - CLE Cleveland Hopkins Intl
PTYCLE
Panama City Tocumen Intl
Tue 1/26
4:41 pm-11:35 am
1 stop18h 54m
Cleveland Hopkins Intl
Sat 1/30
6:00 am-5:12 pm
1 stop11h 12m
$710
Quickest round-trip
Panama CityCleveland
PTY Panama City Tocumen Intl - CLE Cleveland Hopkins Intl
PTYCLE
Panama City Tocumen Intl
Tue 1/5
8:00 am-3:57 pm
1 stop7h 57m
Cleveland Hopkins Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$717
Panama CityCleveland
PTY Panama City Tocumen Intl - CLE Cleveland Hopkins Intl
PTYCLE
Panama City Tocumen Intl
Fri 12/18
4:41 pm-10:15 pm
1 stop29h 34m
Cleveland Hopkins Intl
Fri 12/25
5:59 pm-7:38 pm
1 stop25h 39m
$838
Panama CityCleveland
PTY Panama City Tocumen Intl - CLE Cleveland Hopkins Intl
PTYCLE
Panama City Tocumen Intl
Fri 12/18
12:10 pm-10:41 am
2 stops22h 31m
Cleveland Hopkins Intl
Fri 12/25
7:45 pm-9:20 am
1 stop13h 35m
$1,060
Panama CityCleveland
PTY Panama City Tocumen Intl - CLE Cleveland Hopkins Intl
PTYCLE
Panama City Tocumen Intl
Sun 1/3
8:16 am-9:59 pm
1 stop13h 43m
Cleveland Hopkins Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$1,086
Panama CityCleveland
PTY Panama City Tocumen Intl - CLE Cleveland Hopkins Intl
PTYCLE
Panama City Tocumen Intl
Sun 1/3
4:33 pm-2:00 pm
2 stops21h 27m
Cleveland Hopkins Intl
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$1,217
Showing 1-10 of 12 resultsSorted by cheapest first
Compare providers for flights from Panama City to Cleveland
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Cleveland in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Panama City-Cleveland flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Panama City-Cleveland flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Panama City-Cleveland flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Panama City-Cleveland flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Cleveland flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Panama City to Cleveland
Have a flexible travel schedule? Discover the best time to fly to Cleveland from Panama City with our price prediction graph.
PTY-CLE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Cleveland
Get insights into the airlines that provide service to Cleveland. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cleveland. Reviews last updated November 5, 2026.
Read through reviews of airlines operating flights from Panama City to Cleveland, such as United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.7
Entertainment
7.1
Comfort
7.3
Overall
7.3
Crew
8.1
Food
6.7
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Boarding
7.7
Entertainment
7.1
Comfort
7.3
Overall
7.3
Crew
8.1
Food
6.7
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Related info for your journey
Find useful and relevant information for your journey from Panama City to Cleveland. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Cleveland?
Book flights to Cleveland if you plan to visit one of these locationsSandusky
Beachwood
Independence
Mansfield
Strongsville
Lakewood
Avon
Medina
Streetsboro
North Olmsted
Cuyahoga Falls
Westlake
Elyria
Kent
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Panama City to Cleveland
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Other flights to Cleveland
Explore flights to Cleveland departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on November 5, 2026.
Complete your trip
Complete your trip to Cleveland by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Panama City to Cleveland by cabin class
Find flights from Panama City to Cleveland, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Panama City and Cleveland flights
Browse other Panama City and Cleveland flight options. Last updated on November 5, 2026.
Other flights from Panama City
Browse through other flights departing from Panama City. Flights are based on user searches made on Cheapflights and were last updated on November 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Panama City to Cleveland
Discover the top airline that operate flights from Panama City to Cleveland. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$667 | Average$718 | FlexibilityNo cancel fee | On-time69% |