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$590+ Cheap flights from Panama to Cleveland (CLE)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/26. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CLE
Nov 9 — Nov 161
Sun 11/9
Sun 11/16
1 adult, Economy
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Cheap flight deals from Panama to Cleveland

Keep the following information in mind while searching for Panama to Cleveland flight deals. Data was last updated October 10, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$590
(Avianca Connect)

Popular in

April

Cheapest in

January

Average price

$721
Provider with most accurate pricing for Panama City Tocumen Intl-Cleveland Hopkins Intl flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Cleveland Hopkins Intl flights.
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From Panama to Cleveland Hopkins Intl
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Highest demand for flights based on searches. 9% potential increase in price ($66 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Panama to Cleveland

Cheapest flights from Panama to Cleveland
Explore the most affordable flight options available from Panama to Cleveland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 10, 2025.

This Avianca Connect deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/262:55 amPTY - CLE
2 stops16h 38mMultiple Airlines
Sat 11/85:45 amCLE - PTY
2 stops19h 15mMultiple Airlines
Deal found 10/8$590
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/273:41 pmPTY - CLE
1 stop18h 26mUnited Airlines
Sat 11/86:03 amCLE - PTY
1 stop8h 42mUnited Airlines
Deal found 10/8$591
This United Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/219:45 amPTY - CLE
1 stop8h 39mUnited Airlines
Thu 10/236:05 amCLE - PTY
1 stop13h 32mUnited Airlines
Deal found 10/9$602
This United Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/13:41 pmPTY - CLE
1 stop31h 16mUnited Airlines
Sun 11/96:15 amCLE - PTY
1 stop8h 30mUnited Airlines
Deal found 10/9$612
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/93:30 pmPTY - CLE
1 stop30h 43mUnited Airlines
Thu 10/166:05 amCLE - PTY
1 stop13h 32mUnited Airlines
Deal found 10/8$614
This Kiwi.com deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/219:25 amPTY - CLE
1 stop26h 23mMultiple Airlines
Thu 10/237:56 pmCLE - PTY
2 stops26h 14mMultiple Airlines
Deal found 10/9$621
This American Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/213:15 pmPTY - CLE
2 stops20h 08mAmerican Airlines
Thu 10/237:50 pmCLE - PTY
2 stops19h 13mAmerican Airlines
Deal found 10/9$626
This United Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/193:30 pmPTY - CLE
1 stop30h 43mUnited Airlines
Wed 10/226:15 amCLE - PTY
1 stop8h 59mUnited Airlines
Deal found 10/9$636
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/273:15 pmPTY - CLE
2 stops20h 08mAmerican Airlines
Sat 11/83:35 pmCLE - PTY
2 stops22h 14mAmerican Airlines
Deal found 10/8$638
This Kiwi.com deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/191:30 pmPTY - CLE
2 stops35h 29mMultiple Airlines
Wed 10/222:26 pmCLE - PTY
1 stop30h 07mMultiple Airlines
Deal found 10/9$639
This American Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/203:15 pmPTY - CLE
2 stops21h 52mAmerican Airlines
Wed 10/226:30 pmCLE - PTY
2 stops20h 33mAmerican Airlines
Deal found 10/9$660

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Cleveland that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 10, 2025.
Use the filters below to find and compare flights from Panama to Cleveland that are best for you.

Fly from

Panama

Fly to

Cleveland

Route

Depart

Return

Price

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Sun 10/26

2:55 am-8:33 pm

2 stops16h 38m

Cleveland Hopkins Intl

Sat 11/8

5:45 am-1:00 am

2 stops19h 15m

$590

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Mon 10/27

3:41 pm-11:07 am

1 stop18h 26m

Cleveland Hopkins Intl

Sat 11/8

6:03 am-2:45 pm

1 stop8h 42m

$591

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Tue 10/21

9:45 am-7:24 pm

1 stop8h 39m

Cleveland Hopkins Intl

Thu 10/23

6:05 am-6:37 pm

1 stop13h 32m

$602

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Sat 11/1

3:41 pm-11:57 pm

1 stop31h 16m

Cleveland Hopkins Intl

Sun 11/9

6:15 am-2:45 pm

1 stop8h 30m

$612

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Mon 10/20

10:00 am-11:13 pm

1 stop12h 13m

Cleveland Hopkins Intl

Wed 10/22

6:15 am-2:14 pm

1 stop8h 59m

$614

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Tue 10/21

3:15 pm-12:23 pm

2 stops20h 08m

Cleveland Hopkins Intl

Thu 10/23

7:50 pm-2:03 pm

2 stops19h 13m

$626

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Sun 10/19

3:30 pm-11:13 pm

1 stop30h 43m

Cleveland Hopkins Intl

Wed 10/22

6:15 am-2:14 pm

1 stop8h 59m

$636

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Mon 10/27

3:15 pm-12:23 pm

2 stops20h 08m

Cleveland Hopkins Intl

Sat 11/8

3:35 pm-1:49 pm

2 stops22h 14m

$638

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Mon 10/20

3:15 pm-12:16 am

1 stop8h 01m

Cleveland Hopkins Intl

Wed 10/22

5:30 am-2:03 pm

2 stops9h 33m

$660

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Sun 10/19

3:30 pm-11:08 am

1 stop18h 38m

Cleveland Hopkins Intl

Tue 10/21

3:17 pm-2:14 pm

1 stop23h 57m

$673

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/8

Best time to book a flight from Panama to Cleveland

Have a flexible travel schedule? Discover the best time to fly to Cleveland from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Cleveland

What is the cheapest month to book a flight from Panama to Cleveland?

Currently, December is the cheapest month in which you can book a flight from Panama to Cleveland (average of $391). Flying from Panama to Cleveland in March is currently the most expensive (average of $718). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to CLE?

Find hourly flight availability from Panama to Cleveland. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 10, 2025.

One of the essential ways to save on airfare from Panama to Cleveland is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 44% on airfare.

Reviews of airlines servicing Cleveland

Get insights into the airlines that provide service to Cleveland. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cleveland. Reviews last updated October 10, 2025.
Read through reviews of airlines operating flights from Panama to Cleveland, such as Delta and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,969 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Sally,Oct 2025

ATH - JFK

Only negative outcome of this trip was 3 hour delay, but everything else was fine.
Delta
8.0
Very good
7,969 reviews
Delta
8.0
Very good
7,969 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Sally,Oct 2025

ATH - JFK

Only negative outcome of this trip was 3 hour delay, but everything else was fine.
United Airlines
7.4
Good
8,968 reviews
Delta
8.0
Very good
7,969 reviews

Comfort

7.9

Food

7.3

Entertainment

7.9

Crew

8.5

Overall

8.0

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Sally,Oct 2025

ATH - JFK

Only negative outcome of this trip was 3 hour delay, but everything else was fine.

Related info for your journey

Find useful and relevant information for your journey from Panama to Cleveland. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Cleveland from Panama?

    Located just 10.1 mi from the city center, Cleveland Hopkins Intl (CLE) is the airport most travelers will use when flying to Cleveland from Panama.

  • How long is the flight from Panama to Cleveland?

    Departing from Panama to Cleveland will take you 18h 26m. Panama and Cleveland are separated by a distance of 2238 mi.

  • Can I find deals for flights from Panama to Cleveland that include hotel bookings?

    Yes. In addition to deals on Panama to Cleveland flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Cleveland?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Cleveland.

  • Can I find deals for business class flights from Panama to Cleveland?

    Yes. Cheapflights offers flight deals from Panama to Cleveland by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Cleveland?

    Currently, December is the cheapest month in which you can book a flight from Panama to Cleveland (average of $391). Flying from Panama to Cleveland in March is currently the most expensive (average of $718). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Cleveland?

Book flights to Cleveland if you plan to visit one of these locations
Sandusky
Mentor
Beachwood
Wooster
Avon
Mansfield
Independence
Willoughby
Elyria
Streetsboro
Cleveland Heights
North Olmsted
Cuyahoga Falls
Macedonia
Strongsville
Kent
Medina
Westlake

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama to Cleveland

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Panama to Cleveland

Discover the top 2 airlines that operate flights from Panama to Cleveland. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 10, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$483Average$670FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$580Average$644FlexibilityNo cancel feeOn-time69%

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