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$253+ Cheap flights from Panama to Cleveland (CLE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/2. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CLE
Mar 4 — Mar 111
Wed 3/4
Wed 3/11
1 adult, Economy
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Cheap flight deals from Panama to Cleveland

Cheapest flights from Panama to Cleveland
Explore the most affordable flight options available from Panama to Cleveland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 2, 2026.

This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/163:35 pm
PTY
-
CLE
1 stop7h 39m
American Airlines
Tue 10/276:28 am
CLE
-
PTY
1 stop8h 32m
American Airlines
Deal found 2/1$547
This United Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2210:55 pm
PTY
-
CLE
1 stop10h 02m
United Airlines
Wed 5/276:26 am
CLE
-
PTY
1 stop8h 48m
United Airlines
Deal found 1/31$549
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2410:00 am
PTY
-
CLE
1 stop10h 55m
United Airlines
Tue 5/126:00 am
CLE
-
PTY
1 stop13h 37m
United Airlines
Deal found 2/1$558
This American Airlines deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/221:10 pm
PTY
-
CLE
2 stops24h 51m
American Airlines
Wed 5/273:36 pm
CLE
-
PTY
2 stops21h 34m
American Airlines
Deal found 1/31$559
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/99:30 am
PTY
-
CLE
1 stop9h 46m
United Airlines
Wed 3/116:00 am
CLE
-
PTY
1 stop13h 38m
United Airlines
Deal found 2/2$579
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/241:49 pm
PTY
-
CLE
2 stops19h 43m
American Airlines
Tue 5/127:15 pm
CLE
-
PTY
2 stops18h 31m
American Airlines
Deal found 2/1$584
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/91:40 pm
PTY
-
CLE
1 stop9h 18m
American Airlines
Wed 3/116:05 pm
CLE
-
PTY
2 stops19h 35m
American Airlines
Deal found 2/2$605
This Copa Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/2210:29 pm
PTY
-
CLE
1 stop11h 21m
Copa Airlines
Tue 2/247:20 am
CLE
-
PTY
1 stop9h 48m
Copa Airlines
Deal found 2/1$763
This Mytrip deal was found by Cheapflights users on 1/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2210:10 am
PTY
-
CLE
3 stops29h 30m
Multiple Airlines
Wed 5/275:35 pm
CLE
-
PTY
3 stops40h 40m
Multiple Airlines
Deal found 1/31$794
This American Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/222:40 pm
PTY
-
CLE
2 stops21h 30m
American Airlines
Tue 2/245:43 pm
CLE
-
PTY
2 stops19h 57m
American Airlines
Deal found 2/1$1,065

Find flight deals from Panama to Cleveland

Keep the following information in mind while searching for Panama to Cleveland flight deals. Data was last updated February 2, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$549
(United Airlines)

One-way from

$253
(Kiwi.com)

Popular in

April

Cheapest in

November

Average price

$527
Provider with most accurate pricing for Panama City Tocumen Intl-Cleveland Hopkins Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Cleveland Hopkins Intl flights.
Search Deals
From Panama to Cleveland Hopkins Intl
Search Deals
One-way flight from Panama to Cleveland Hopkins Intl
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($68 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Cleveland that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 2, 2026.
Use the filters below to find and compare flights from Panama to Cleveland that are best for you.

Fly from

Panama

Fly to

Cleveland

Route

Depart

Return

Price

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Fri 5/22

10:55 pm-9:57 am

1 stop10h 02m

Cleveland Hopkins Intl

Wed 5/27

6:26 am-2:14 pm

1 stop8h 48m

$549

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Fri 4/24

10:00 am-9:55 pm

1 stop10h 55m

Cleveland Hopkins Intl

Tue 5/12

6:00 am-6:37 pm

1 stop13h 37m

$558

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Fri 5/22

1:10 pm-3:01 pm

2 stops24h 51m

Cleveland Hopkins Intl

Wed 5/27

3:51 pm-12:10 pm

2 stops21h 19m

$559

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Mon 3/9

9:30 am-8:16 pm

1 stop9h 46m

Cleveland Hopkins Intl

Wed 3/11

6:00 am-6:38 pm

1 stop13h 38m

$579

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Fri 4/24

1:49 pm-12:42 pm

2 stops21h 53m

Cleveland Hopkins Intl

Tue 5/12

6:04 am-12:46 pm

1 stop7h 42m

$584

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Mon 3/9

3:10 pm-11:47 am

2 stops19h 37m

Cleveland Hopkins Intl

Wed 3/11

7:23 pm-2:20 pm

2 stops19h 57m

$605

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Mon 3/2

9:45 am-3:15 pm

3 stops53h 30m

$253

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Mon 3/2

11:35 am-5:19 pm

1 stop29h 44m

$318

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/1

Best time to book a flight from Panama to Cleveland

Have a flexible travel schedule? Discover the best time to fly to Cleveland from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Cleveland

What is the cheapest month to book a flight from Panama to Cleveland?

Currently, May is the cheapest month in which you can book a flight from Panama to Cleveland (average of $487). Flying from Panama to Cleveland in March is currently the most expensive (average of $718). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Cleveland

Get insights into the airlines that provide service to Cleveland. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cleveland. Reviews last updated February 2, 2026.
Read through reviews of airlines operating flights from Panama to Cleveland, such as Delta and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,128 reviews

Boarding

8.1

Crew

8.5

Food

7.2

Entertainment

7.8

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,128 reviews
Delta
7.9
Good
8,128 reviews

Boarding

8.1

Crew

8.5

Food

7.2

Entertainment

7.8

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,222 reviews
Delta
7.9
Good
8,128 reviews

Boarding

8.1

Crew

8.5

Food

7.2

Entertainment

7.8

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Panama to Cleveland. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Cleveland from Panama?

    Located just 10.1 mi from the city center, Cleveland Hopkins Intl (CLE) is the airport most travelers will use when flying to Cleveland from Panama.

  • How long is the flight from Panama to Cleveland?

    Departing from Panama to Cleveland will take you 10h 02m. Panama and Cleveland are separated by a distance of 2238 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Panama to Cleveland that include hotel bookings?

    Yes. In addition to deals on Panama to Cleveland flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Cleveland?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Cleveland.

  • Can I find deals for business class flights from Panama to Cleveland?

    Yes. Cheapflights offers flight deals from Panama to Cleveland by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Cleveland?

    Currently, May is the cheapest month in which you can book a flight from Panama to Cleveland (average of $487). Flying from Panama to Cleveland in March is currently the most expensive (average of $718). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Cleveland?

Book flights to Cleveland if you plan to visit one of these locations
Sandusky
Mentor
Mansfield
Avon
Independence
Wooster
Beachwood
Willoughby
Lakewood
Streetsboro
Cleveland Heights
North Olmsted
Cuyahoga Falls
Macedonia
Kent
Medina
Strongsville
Elyria

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Panama to Cleveland

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Panama to Cleveland

Discover the top 2 airlines that operate flights from Panama to Cleveland. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 2, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$504Average$677FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$613Average$644FlexibilityNo cancel feeOn-time69%

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