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$296+ Cheap flights from Panama to Cleveland (CLE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/3. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CLE
Jan 8 — Jan 151
Thu 1/8
Thu 1/15
1 adult, Economy
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Cheap flight deals from Panama to Cleveland

Cheapest flights from Panama to Cleveland
Explore the most affordable flight options available from Panama to Cleveland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 9, 2025.

This Copa Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1410:29 pmPTY - CLE
1 stop11h 17mCopa Airlines
Tue 12/2310:55 amCLE - PTY
1 stop9h 40mCopa Airlines
Deal found 12/8$741
This Kiwi.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/132:55 amPTY - CLE
2 stops28h 58mMultiple Airlines
Tue 12/235:35 pmCLE - PTY
1 stop15h 05mMultiple Airlines
Deal found 12/8$772
This American Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/144:43 pmPTY - CLE
2 stops16h 49mAmerican Airlines
Tue 12/236:00 amCLE - PTY
2 stops9h 54mAmerican Airlines
Deal found 12/8$874
This United Airlines deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/144:41 pmPTY - CLE
1 stop29h 09mUnited Airlines
Wed 12/2412:15 pmCLE - PTY
1 stop7h 47mUnited Airlines
Deal found 12/8$2,161
This Booking.com deal was found by Cheapflights users on 12/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/145:50 pmPTY - CLE
2 stops23h 40mMultiple Airlines
Wed 12/246:10 pmCLE - PTY
2 stops19h 50mMultiple Airlines
Deal found 12/8$4,313

Find flight deals from Panama to Cleveland

Keep the following information in mind while searching for Panama to Cleveland flight deals. Data was last updated December 9, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$557
(United Airlines)

One-way from

$296
(Kiwi.com)

Popular in

April

Cheapest in

January

Average price

$547
Provider with most accurate pricing for Panama City Tocumen Intl-Cleveland Hopkins Intl flight deals.
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Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Cleveland Hopkins Intl flights.
Search Deals
From Panama to Cleveland Hopkins Intl
Search Deals
One-way flight from Panama to Cleveland Hopkins Intl
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($86 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama to Cleveland that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 9, 2025.
Use the filters below to find and compare flights from Panama to Cleveland that are best for you.

Fly from

Panama

Fly to

Cleveland

Route

Depart

Return

Price

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Sat 1/24

4:41 pm-11:08 am

1 stop18h 27m

Cleveland Hopkins Intl

Tue 1/27

6:00 am-5:07 pm

1 stop11h 07m

$557

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Tue 3/3

7:50 pm-1:28 pm

2 stops41h 38m

$296

Panama CityCleveland

PTY - CLE

PTYCLE

Panama City Tocumen Intl

Tue 3/3

3:20 pm-12:30 am

1 stop9h 10m

$307

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/7

Best time to book a flight from Panama to Cleveland

Have a flexible travel schedule? Discover the best time to fly to Cleveland from Panama with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama to Cleveland

What is the cheapest month to book a flight from Panama to Cleveland?

Currently, May is the cheapest month in which you can book a flight from Panama to Cleveland (average of $487). Flying from Panama to Cleveland in March is currently the most expensive (average of $718). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA to CLE?

Find hourly flight availability from Panama to Cleveland. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 9, 2025.

One of the essential ways to save on airfare from Panama to Cleveland is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the afternoon could potentially save you up to 11% on airfare.

Reviews of airlines servicing Cleveland

Get insights into the airlines that provide service to Cleveland. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cleveland. Reviews last updated December 9, 2025.
Read through reviews of airlines operating flights from Panama to Cleveland, such as Delta and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,011 reviews

Crew

8.5

Entertainment

7.9

Boarding

8.1

Food

7.3

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,011 reviews
Delta
7.9
Good
8,011 reviews

Crew

8.5

Entertainment

7.9

Boarding

8.1

Food

7.3

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,089 reviews
Delta
7.9
Good
8,011 reviews

Crew

8.5

Entertainment

7.9

Boarding

8.1

Food

7.3

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Panama to Cleveland. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Cleveland from Panama?

    Located just 10.1 mi from the city center, Cleveland Hopkins Intl (CLE) is the airport most travelers will use when flying to Cleveland from Panama.

  • How long is the flight from Panama to Cleveland?

    Departing from Panama to Cleveland will take you 18h 27m. Panama and Cleveland are separated by a distance of 2238 mi.

  • Can I find deals for flights from Panama to Cleveland that include hotel bookings?

    Yes. In addition to deals on Panama to Cleveland flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama to Cleveland?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama to Cleveland.

  • Can I find deals for business class flights from Panama to Cleveland?

    Yes. Cheapflights offers flight deals from Panama to Cleveland by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama to Cleveland?

    Currently, May is the cheapest month in which you can book a flight from Panama to Cleveland (average of $487). Flying from Panama to Cleveland in March is currently the most expensive (average of $718). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Cleveland?

Book flights to Cleveland if you plan to visit one of these locations
Sandusky
Mentor
Mansfield
Avon
Beachwood
Wooster
Independence
Willoughby
Lakewood
Streetsboro
Medina
Cleveland Heights
North Olmsted
Cuyahoga Falls
Macedonia
Kent
Strongsville
Elyria
Westlake

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Alternative routes for Panama to Cleveland

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Panama to Cleveland

Discover the top 2 airlines that operate flights from Panama to Cleveland. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 9, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$483Average$568FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$613Average$644FlexibilityNo cancel feeOn-time69%

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