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Chile

$714+ Cheap flights from Knoxville (TYS) to Chile

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/19. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — SCL
Jan 3 — Jan 101
Sat 1/3
Sat 1/10
1 adult, Economy
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Cheap flight deals from Knoxville to Chile

Best flights from Knoxville to Chile
Discover carefully curated flight deals from Knoxville to Chile that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 4, 2025.

This LATAM Airlines deal was found by Cheapflights users on 12/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/192:38 pmTYS - SCL
1 stop16h 02mLATAM Airlines
Mon 3/235:15 amSCL - TYS
2 stops19h 36mLATAM Airlines
Deal found 12/1$714
This United Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/197:00 amTYS - SCL
3 stops23h 50mUnited Airlines
Mon 3/239:45 pmSCL - TYS
2 stops24h 02mUnited Airlines
Deal found 12/3$769
This Travelocity deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/612:00 pmTYS - SCL
2 stops17h 00mLATAM Airlines
Sat 3/146:52 pmSCL - TYS
3 stops53h 59mLATAM Airlines
Deal found 12/3$890

Find flight deals from Knoxville to Chile

Keep the following information in mind while searching for Knoxville to Chile flight deals. Data was last updated December 4, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
1 star

Round-trip from

$714
(LATAM Airlines)
Provider with most accurate pricing for Knoxville McGhee Tyson-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Santiago Arturo Merino Benitez flights.
Search Deals
From Knoxville McGhee Tyson to Chile
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Chile that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Knoxville to Chile that are best for you.

Fly from

Knoxville

Fly to

Chile

Route

Depart

Return

Price

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

Thu 3/19

2:38 pm-7:40 am

1 stop16h 02m

Santiago Arturo Merino Benitez

Mon 3/23

5:15 am-11:51 pm

2 stops19h 36m

$714

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

Thu 3/19

7:00 am-7:50 am

3 stops23h 50m

Santiago Arturo Merino Benitez

Mon 3/23

9:45 pm-8:47 pm

2 stops24h 02m

$769

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

Fri 3/6

12:00 pm-7:00 am

2 stops17h 00m

Santiago Arturo Merino Benitez

Sat 3/14

6:52 pm-11:51 pm

3 stops53h 59m

$890

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/1

Best time to book a flight from Knoxville to Chile

Have a flexible travel schedule? Discover the best time to fly to Chile from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Chile

What is the cheapest time of day to fly from TYS to CL?

Find hourly flight availability from Knoxville to Chile. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 4, 2025.

A simple way to save on the total cost of your ticket is to fly from Knoxville to Chile in the morning. If you’re flexible enough to do this you can expect to save up to 80% on your trip compared to booking a flight in the evening.

Reviews of airlines servicing Chile

Get insights into the airlines that provide service to Chile. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chile. Reviews last updated December 4, 2025.
Get a feel of what it's like to fly with American Airlines from Knoxville to Chile by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,047 reviews

Comfort

7.2

Crew

8.0

Boarding

7.5

Entertainment

6.9

Overall

7.2

Food

6.5

Reviews

1 / 20
4.0
Okay

Cameron,Nov 2025

PDX - LHR

The plane was very old...had no WiFi available. The crew were not friendly nor helpful.
American Airlines
7.2
Good
11,047 reviews
American Airlines
7.2
Good
11,047 reviews

Comfort

7.2

Crew

8.0

Boarding

7.5

Entertainment

6.9

Overall

7.2

Food

6.5

Reviews

1 / 20
4.0
Okay

Cameron,Nov 2025

PDX - LHR

The plane was very old...had no WiFi available. The crew were not friendly nor helpful.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Chile. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Chile?

    Knoxville McGhee Tyson (TYS), located 11.3 mi from the city center, is the airport you fly out of when you book flights from Knoxville to Chile.

  • How long is the flight from Knoxville to Chile?

    Departing from Knoxville to Chile will take you 16h 02m. Knoxville and Chile are separated by a distance of 4853 mi.

  • Can I find deals for flights from Knoxville to Chile that include hotel bookings?

    Yes. In addition to deals on Knoxville to Chile flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Chile?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Chile.

  • Can I find deals for business class flights from Knoxville to Chile?

    Yes. Cheapflights offers flight deals from Knoxville to Chile by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top airline flying from Knoxville to Chile

Discover the top airline that operate flights from Knoxville to Chile. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$678Average$931FlexibilityNo cancel feeOn-time71%

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