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$524+ Cheap flights from Knoxville (TYS) to Chile

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/4. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — SCL
Aug 22 — Aug 291
Fri 8/22
Fri 8/29
1 adult, Economy
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Cheap flight deals from Knoxville to Chile

Keep the following information in mind while searching for Knoxville to Chile flight deals. Data was last updated August 17, 2025.

Round-trip from

$747
(American Airlines)

One-way from

$524
(United Airlines)
From Knoxville McGhee Tyson to Chile
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One-way flight from Knoxville McGhee Tyson to Chile
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Find flight deals from Knoxville to Chile

Cheapest flights from Knoxville to Chile
Explore the most affordable flight options available from Knoxville to Chile. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 17, 2025.

This American Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/116:10 amTYS - SCL
1 stop24h 45mAmerican Airlines
Thu 9/189:55 pmSCL - TYS
2 stops22h 10mAmerican Airlines
Deal found 8/15$747
This Orbitz deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/116:08 pmTYS - SCL
1 stop11h 52mLATAM Airlines
Wed 9/1712:25 amSCL - TYS
2 stops24h 19mLATAM Airlines
Deal found 8/15$799
This Kiwi.com deal was found by Cheapflights users on 8/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/173:22 pmTYS - SCL
1 stop15h 23mMultiple Airlines
Sun 8/2411:55 pmSCL - TYS
2 stops17h 43mMultiple Airlines
Deal found 8/16$823
This Expedia deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/216:36 pmTYS - SCL
3 stops24h 59mLATAM Airlines
Sun 12/284:40 pmSCL - TYS
2 stops33h 14mLATAM Airlines
Deal found 8/15$878
This United Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2111:00 amTYS - SCL
2 stops43h 50mUnited Airlines
Sun 12/2810:45 pmSCL - TYS
1 stop21h 25mUnited Airlines
Deal found 8/15$885

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Chile that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 17, 2025.
Use the filters below to find and compare flights from Knoxville to Chile that are best for you.

Fly from

Knoxville

Fly to

Chile

Route

Depart

Return

Price

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

Thu 9/11

6:10 am-7:55 am

1 stop24h 45m

Santiago Arturo Merino Benitez

Thu 9/18

9:55 pm-7:05 pm

2 stops22h 10m

$747

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

Thu 9/11

6:08 pm-7:00 am

1 stop11h 52m

Santiago Arturo Merino Benitez

Wed 9/17

12:25 am-11:44 pm

2 stops24h 19m

$799

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

Sun 12/21

6:36 pm-9:35 pm

3 stops24h 59m

Santiago Arturo Merino Benitez

Sun 12/28

4:40 pm-11:54 pm

2 stops33h 14m

$878

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

Sun 12/21

11:00 am-8:50 am

2 stops43h 50m

Santiago Arturo Merino Benitez

Sun 12/28

10:45 pm-6:10 pm

1 stop21h 25m

$885

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

Sun 1/4

5:35 pm-8:50 am

2 stops37h 15m

$524

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

Sun 1/4

5:28 am-7:50 am

1 stop24h 22m

$558

KnoxvilleSantiago

TYS - SCL

TYSSCL

Knoxville McGhee Tyson

Sun 1/4

11:55 am-2:30 pm

3 stops24h 35m

$578

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/16

Best time to book a flight from Knoxville to Chile

Have a flexible travel schedule? Discover the best time to fly to Chile from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Chile

What is the cheapest time of day to fly from TYS to CL?

Find hourly flight availability from Knoxville to Chile. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 17, 2025.

When flying from Knoxville to Chile, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Chile

Get insights into the airlines that provide service to Chile. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chile. Reviews last updated August 17, 2025.
Get a feel of what it's like to fly with American Airlines from Knoxville to Chile by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Food

6.5

Boarding

7.5

Entertainment

6.9

Comfort

7.2

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Crew

8.0

Food

6.5

Boarding

7.5

Entertainment

6.9

Comfort

7.2

Overall

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Chile. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Chile?

    Knoxville McGhee Tyson (TYS), located 11.3 mi from the city center, is the airport you fly out of when you book flights from Knoxville to Chile.

  • Can I find deals for flights from Knoxville to Chile that include hotel bookings?

    Yes. In addition to deals on Knoxville to Chile flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Chile?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Chile.

  • Can I find deals for business class flights from Knoxville to Chile?

    Yes. Cheapflights offers flight deals from Knoxville to Chile by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Chile?

    Currently, April is the cheapest month in which you can book a flight from Knoxville to Chile (average of $752). Flying from Knoxville to Chile in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from Knoxville to Chile

Discover the top airline that operate flights from Knoxville to Chile. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$692Average$931FlexibilityNo cancel feeOn-time71%

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