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$66+ Cheap flights from Panama City Beach, FL to Chicago (CHI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
PNS — CHI
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Panama City Beach to Chicago

Keep the following information in mind while searching for Panama City Beach to Chicago flight deals. Data was last updated September 16, 2025.

Round-trip from

$159
(American Airlines)

One-way from

$66
(United Airlines)

Popular in

September

Cheapest in

February

Average price

$417
From Panama City Beach to Chicago (CHI)
Search Deals
One-way flight from Panama City Beach to Chicago (CHI)
Search Deals
Highest demand for flights based on searches. 15% potential increase in price ($59 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Panama City Beach to Chicago

Cheapest flights from Panama City Beach to Chicago
Explore the most affordable flight options available from Panama City Beach to Chicago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/81:21 pmECP - ORD
1 stop6h 08mAmerican Airlines
Tue 11/116:46 amORD - ECP
1 stop4h 43mAmerican Airlines
Deal found 9/14$159
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/237:20 pmECP - MDW
1 stop3h 55mSouthwest
Sun 10/2610:35 amMDW - ECP
1 stop7h 05mSouthwest
Deal found 9/15$183
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/236:17 pmECP - ORD
1 stop5h 41mDelta
Sun 10/266:45 amORD - ECP
1 stop5h 45mDelta
Deal found 9/15$197
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/246:17 pmECP - MDW
1 stop3h 57mDelta
Mon 10/2710:35 amMDW - ECP
1 stop4h 45mDelta
Deal found 9/14$197
This United Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/171:55 pmECP - ORD
Nonstop2h 40mUnited Airlines
Mon 10/2010:40 amORD - ECP
Nonstop2h 30mUnited Airlines
Deal found 9/15$201
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1411:00 amECP - MDW
1 stop8h 05mSouthwest
Tue 10/215:15 amMDW - ECP
1 stop7h 45mSouthwest
Deal found 9/14$234
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/141:47 pmECP - ORD
1 stop5h 29mAmerican Airlines
Tue 10/217:10 amORD - ECP
1 stop7h 56mAmerican Airlines
Deal found 9/14$238
This Southwest deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/87:50 amECP - ORD
2 stops14h 00mSouthwest
Tue 11/111:45 pmORD - ECP
1 stop5h 20mSouthwest
Deal found 9/14$262
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/223:41 pmECP - ORD
1 stop7h 13mAmerican Airlines
Fri 10/245:20 amORD - ECP
1 stop6h 08mAmerican Airlines
Deal found 9/13$272
This United Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/221:55 pmECP - ORD
Nonstop2h 40mUnited Airlines
Fri 10/2410:40 amORD - ECP
Nonstop2h 30mUnited Airlines
Deal found 9/13$285
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/232:40 pmECP - ORD
1 stop6h 44mAmerican Airlines
Sun 10/2610:26 amORD - ECP
1 stop8h 18mAmerican Airlines
Deal found 9/14$298
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/89:50 amECP - MDW
1 stop8h 15mSouthwest
Sun 10/126:45 pmMDW - ECP
1 stop3h 25mSouthwest
Deal found 9/15$301

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City Beach to Chicago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Panama City Beach to Chicago that are best for you.

Fly from

Panama City Beach

Fly to

Chicago

Route

Depart

Return

Price

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Thu 10/23

7:20 pm-11:15 pm

1 stop3h 55m

Chicago Midway

Sun 10/26

10:35 am-5:40 pm

1 stop7h 05m

$183

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Fri 10/24

9:25 am-5:45 pm

1 stop8h 20m

Chicago Midway

Sun 10/26

10:35 am-5:40 pm

1 stop7h 05m

$183

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Thu 10/23

6:17 pm-11:58 pm

1 stop5h 41m

Chicago O'Hare Intl

Sun 10/26

6:45 am-12:30 pm

1 stop5h 45m

$197

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Mon 11/10

6:40 pm-12:01 am

1 stop5h 21m

Chicago O'Hare Intl

Mon 11/17

11:14 am-5:55 pm

1 stop6h 41m

$197

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Thu 10/23

6:17 pm-11:58 pm

1 stop5h 41m

Chicago O'Hare Intl

Tue 10/28

6:45 am-12:40 pm

1 stop5h 55m

$197

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Fri 10/24

1:35 pm-6:49 pm

1 stop5h 14m

Chicago O'Hare Intl

Mon 10/27

6:45 am-12:30 pm

1 stop5h 45m

$197

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Fri 10/24

6:17 pm-10:14 pm

1 stop3h 57m

Chicago Midway

Mon 10/27

10:35 am-3:20 pm

1 stop4h 45m

$197

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Thu 10/23

6:00 am-9:51 am

1 stop3h 51m

Chicago Midway

Tue 10/28

10:35 am-3:20 pm

1 stop4h 45m

$197

Panama CityChicago

ECP - MDW

ECPMDW

Panama City NW Florida Beaches

Fri 10/24

4:25 pm-10:14 pm

1 stop5h 49m

Chicago Midway

Tue 10/28

5:04 pm-11:10 pm

1 stop6h 06m

$197

Panama CityChicago

ECP - ORD

ECPORD

Panama City NW Florida Beaches

Fri 10/17

1:55 pm-4:35 pm

Nonstop2h 40m

Chicago O'Hare Intl

Mon 10/20

10:40 am-1:10 pm

Nonstop2h 30m

$201

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 38 results
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Best time to book a flight from Panama City Beach to Chicago

Have a flexible travel schedule? Discover the best time to fly to Chicago from Panama City Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City Beach to Chicago

What is the cheapest month to book a flight from Panama City Beach to Chicago?

Currently, August is the cheapest month in which you can book a flight from Panama City Beach to Chicago (average of $245). Flying from Panama City Beach to Chicago in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PA9 to CHI?

Find hourly flight availability from Panama City Beach to Chicago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City Beach to Chicago as you normally would.

What is the cheapest day to fly from Panama City Beach to Chicago?

Use this chart to determine the cheapest time to fly round-trip from Panama City Beach to Chicago. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Panama City Beach to Chicago flight should consider departing on Thursday afternoons when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Chicago

Get insights into the airlines that provide service to Chicago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Chicago. Reviews last updated September 16, 2025.
See what other customers who have flown with Southwest, Delta, and United Airlines from Panama City Beach to Chicago have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Crew

8.6

Boarding

8.1

Food

7.0

Comfort

8.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Crew

8.6

Boarding

8.1

Food

7.0

Comfort

8.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.
Delta
8.0
Very good
7,957 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Crew

8.6

Boarding

8.1

Food

7.0

Comfort

8.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.
United Airlines
7.4
Good
8,924 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Crew

8.6

Boarding

8.1

Food

7.0

Comfort

8.0

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Anonymous,Feb 2025

MCO - STL

Cancelled at last minute, SWA unable to assist in formulating alternate plans. Wound up renting a car and driving 13 hours to beat bad weather forecast at home. Not SWA’s fault that there was significant bad weather across the country.

Related info for your journey

Find useful and relevant information for your journey from Panama City Beach to Chicago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Panama City Beach to Chicago?

    A quick flight from Panama City Beach to Chicago can take about 2h 40m. Southwest provides one of the quickest options available for as low as $201. Panama City Beach and Chicago are separated by a distance of 811 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most reliable airlines from Panama City Beach to Chicago?

    The top 3 most reliable airlines when flying from Panama City Beach to Chicago are Lufthansa (81%), Emirates (80%) and United Airlines (80%).

  • What are the cheapest flights from Panama City Beach to Chicago?

    The cheapest flight price from Panama City Beach to Chicago is $125. On average you can expect to pay $291. The most popular route, (Panama City NW Florida Beaches - Chicago O'Hare Intl), can usually be booked for $197.

  • Can I find deals for flights from Panama City Beach to Chicago that include hotel bookings?

    Yes. In addition to deals on Panama City Beach to Chicago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City Beach to Chicago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City Beach to Chicago.

  • Can I find deals for business class flights from Panama City Beach to Chicago?

    Yes. Cheapflights offers flight deals from Panama City Beach to Chicago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City Beach to Chicago?

    Currently, August is the cheapest month in which you can book a flight from Panama City Beach to Chicago (average of $245). Flying from Panama City Beach to Chicago in March is currently the most expensive (average of $321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Chicago?

Book flights to Chicago if you plan to visit one of these locations
Merrillville
Lansing
Hammond
Benton Harbor
Porter
Chesterton

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Top 5 airlines flying from Panama City Beach to Chicago

Discover the top 5 airlines that operate flights from Panama City Beach to Chicago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$155Average$213FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$157Average$405FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$173Average$324FlexibilityNo cancel feeOn-time63%
DeltaCheapest$194Average$389FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$211Average$378FlexibilityNo cancel feeOn-time69%

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