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$54+ Cheap flights from Florida Keys to Charleston (CHS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/14. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — CHS
Jan 30 — Feb 61
Fri 1/30
Fri 2/6
1 adult, Economy
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Cheap flight deals from Florida Keys to Charleston

Cheapest flights from Florida Keys to Charleston
Explore the most affordable flight options available from Florida Keys to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 31, 2025.

This American Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/307:00 amMIA - CHS
Nonstop1h 47mAmerican Airlines
Mon 1/127:20 pmCHS - MIA
Nonstop1h 57mAmerican Airlines
Deal found 12/29$244
This Delta deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:01 pmMIA - CHS
1 stop6h 57mDelta
Mon 1/125:18 pmCHS - MIA
1 stop5h 30mDelta
Deal found 12/29$294
This American Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:00 amMIA - CHS
Nonstop1h 47mAmerican Airlines
Sat 1/39:27 amCHS - MIA
Nonstop1h 53mAmerican Airlines
Deal found 12/30$309
This American Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/305:35 pmMIA - CHS
Nonstop1h 52mAmerican Airlines
Thu 1/16:00 amCHS - MIA
Nonstop1h 42mAmerican Airlines
Deal found 12/29$355
This Southwest deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3012:10 pmMIA - CHS
1 stop7h 10mSouthwest
Sat 1/31:55 pmCHS - MIA
1 stop5h 05mSouthwest
Deal found 12/28$357
This Delta deal was found by Cheapflights users on 12/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:01 pmMIA - CHS
1 stop5h 38mDelta
Fri 1/212:23 pmCHS - MIA
1 stop4h 55mDelta
Deal found 12/31$364
This American Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3010:56 pmMIA - CHS
Nonstop1h 49mAmerican Airlines
Sat 1/39:27 amCHS - MIA
Nonstop1h 53mAmerican Airlines
Deal found 12/30$371

Find flight deals from Florida Keys to Charleston

Keep the following information in mind while searching for Florida Keys to Charleston flight deals. Data was last updated December 31, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$107
(American Airlines)

One-way from

$54
(American Airlines)
Provider with most accurate pricing for Key West-Charleston flight deals.
Search Deals
Provider most trusted by Cheapflights users for Key West-Charleston flights.
Search Deals
From Florida Keys to Charleston
Search Deals
One-way flight from Florida Keys to Charleston
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florida Keys to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 31, 2025.
Use the filters below to find and compare flights from Florida Keys to Charleston that are best for you.

Fly from

Florida Keys

Fly to

Charleston

Route

Depart

Return

Price

MiamiCharleston

MIA - CHS

MIACHS

Miami

Fri 2/13

10:00 pm-11:59 pm

Nonstop1h 59m

Charleston

Mon 2/16

8:13 pm-10:05 pm

Nonstop1h 52m

$107

MiamiCharleston

MIA - CHS

MIACHS

Miami

Sat 2/14

10:00 pm-11:59 pm

Nonstop1h 59m

Charleston

Mon 2/16

8:13 pm-10:05 pm

Nonstop1h 52m

$107

MiamiCharleston

MIA - CHS

MIACHS

Miami

Wed 2/18

8:30 am-10:26 am

Nonstop1h 56m

Charleston

Mon 2/23

11:06 am-12:56 pm

Nonstop1h 50m

$107

MiamiCharleston

MIA - CHS

MIACHS

Miami

Thu 1/22

4:52 pm-4:10 pm

1 stop23h 18m

Charleston

Mon 1/26

5:05 pm-1:21 pm

1 stop20h 16m

$142

MiamiCharleston

MIA - CHS

MIACHS

Miami

Wed 1/21

5:50 am-11:48 am

1 stop5h 58m

Charleston

Sat 1/24

5:43 pm-12:51 am

1 stop7h 08m

$157

MiamiCharleston

MIA - CHS

MIACHS

Miami

Sat 1/17

7:15 am-1:28 pm

1 stop6h 13m

Charleston

Mon 1/19

7:00 pm-12:51 am

1 stop5h 51m

$157

MiamiCharleston

MIA - CHS

MIACHS

Miami

Wed 1/21

4:50 pm-6:40 pm

Nonstop1h 50m

Charleston

Sat 1/24

6:23 pm-8:20 pm

Nonstop1h 57m

$157

MiamiCharleston

MIA - CHS

MIACHS

Miami

Sat 1/24

5:50 am-12:05 pm

1 stop6h 15m

Charleston

Sun 1/25

3:28 pm-8:44 pm

1 stop5h 16m

$177

MiamiCharleston

MIA - CHS

MIACHS

Miami

Wed 1/14

10:29 am-4:06 pm

1 stop5h 37m

Charleston

Sat 1/24

5:43 pm-12:51 am

1 stop7h 08m

$177

MiamiCharleston

MIA - CHS

MIACHS

Miami

Wed 1/28

12:00 pm-5:53 pm

1 stop5h 53m

Charleston

Wed 2/4

3:28 pm-9:41 pm

1 stop6h 13m

$177

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/29

Showing 1-10 of 36 results
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Best time to book a flight from Florida Keys to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from Florida Keys with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florida Keys to Charleston
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Charleston

Get insights into the airlines that provide service to Charleston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charleston. Reviews last updated December 31, 2025.
Get a feel of what it's like to fly with American Airlines and Spirit Airlines from Florida Keys to Charleston by reading reviews from past customers. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,074 reviews

Crew

8.0

Entertainment

6.9

Overall

7.2

Boarding

7.5

Comfort

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
American Airlines
7.2
Good
11,074 reviews
American Airlines
7.2
Good
11,074 reviews

Crew

8.0

Entertainment

6.9

Overall

7.2

Boarding

7.5

Comfort

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.
Spirit Airlines
6.3
Okay
8,245 reviews
American Airlines
7.2
Good
11,074 reviews

Crew

8.0

Entertainment

6.9

Overall

7.2

Boarding

7.5

Comfort

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Anonymous,Aug 2025

MIA - DCA

Flight delayed 5 hours and was told it was due to mechanical issues. Instead of providing lodging due to missed connecting flight, American changed the cause of delay to weather, which meant they were not able required to provide a hotel. To make matters worse, one of our checked bags was lost even though its status said it was “by the plane” but no one at the service desk seemed able to locate it.

Related info for your journey

Find useful and relevant information for your journey from Florida Keys to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Charleston from Florida Keys?

    If you book a flight to Charleston from Florida Keys, you will be flying to Charleston, which is the city’s only airport. Charleston (CHS) is located 10.2 mi from the center of Charleston.

  • How long is the flight from Florida Keys to Charleston?

    American Airlines and Delta can get you from Florida Keys to Charleston in just under 1h 59m. Your travel time can differ by up to 3h 59m. The distance between Florida Keys and Charleston is about 490 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Florida Keys to Charleston one-way?

    The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $31. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from Florida Keys to Charleston for a low price.

  • Can I find deals for flights from Florida Keys to Charleston that include hotel bookings?

    Yes. In addition to deals on Florida Keys to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florida Keys to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florida Keys to Charleston.

  • Can I find deals for business class flights from Florida Keys to Charleston?

    Yes. Cheapflights offers flight deals from Florida Keys to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Santee
Summerville
Walterboro
Isle of Palms
Mount Pleasant
Edisto Beach

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Top airline flying from Florida Keys to Charleston

Discover the top airline that operate flights from Florida Keys to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$387Average$658FlexibilityNo cancel feeOn-time71%

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