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Charleston

$49+ Cheap flights from Florida Keys to Charleston (CHS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — CHS
Dec 10 — Dec 171
Wed 12/10
Wed 12/17
1 adult, Economy
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Find flight deals from Florida Keys to Charleston

Cheapest flights from Florida Keys to Charleston
Explore the most affordable flight options available from Florida Keys to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 10, 2025.

This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/511:03 pmMIA - CHS
Nonstop1h 43mAmerican Airlines
Sun 12/76:00 amCHS - MIA
Nonstop1h 44mAmerican Airlines
Deal found 11/10$97
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/47:03 amMIA - CHS
Nonstop1h 42mAmerican Airlines
Mon 12/88:10 pmCHS - MIA
Nonstop1h 50mAmerican Airlines
Deal found 11/9$98
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2610:56 pmMIA - CHS
Nonstop1h 49mAmerican Airlines
Wed 1/146:00 amCHS - MIA
Nonstop1h 49mAmerican Airlines
Deal found 11/8$125
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2610:56 pmMIA - CHS
Nonstop1h 49mAmerican Airlines
Tue 12/308:07 pmCHS - MIA
Nonstop1h 53mAmerican Airlines
Deal found 11/10$131
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/127:03 amMIA - CHS
Nonstop1h 42mAmerican Airlines
Sun 12/148:10 pmCHS - MIA
Nonstop1h 50mAmerican Airlines
Deal found 11/10$132
This Mytrip deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/68:53 pmMIA - CHS
1 stop14h 07mSpirit Airlines
Sat 12/1311:55 amCHS - MIA
1 stop11h 26mSpirit Airlines
Deal found 11/8$134
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/119:03 pmMIA - CHS
1 stop13h 57mMultiple Airlines
Sat 12/1311:55 amCHS - MIA
1 stop11h 26mMultiple Airlines
Deal found 11/9$139
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/175:30 pmMIA - CHS
Nonstop1h 44mAmerican Airlines
Sat 12/278:07 pmCHS - MIA
Nonstop1h 53mAmerican Airlines
Deal found 11/9$142
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2510:19 pmMIA - CHS
Nonstop1h 44mAmerican Airlines
Tue 12/29:27 amCHS - MIA
Nonstop1h 46mAmerican Airlines
Deal found 11/10$144
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/297:00 amMIA - CHS
Nonstop1h 47mAmerican Airlines
Fri 1/28:07 pmCHS - MIA
Nonstop1h 53mAmerican Airlines
Deal found 11/9$156
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/410:32 amMIA - CHS
1 stop4h 43mDelta
Mon 12/84:06 pmCHS - MIA
1 stop6h 08mDelta
Deal found 11/9$157
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/238:55 amEYW - CHS
1 stop24h 02mBreeze Airways
Thu 11/272:59 pmCHS - EYW
1 stop17h 16mBreeze Airways
Deal found 11/8$174

Cheap flight deals from Florida Keys to Charleston

Keep the following information in mind while searching for Florida Keys to Charleston flight deals. Data was last updated November 10, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$97
(American Airlines)

One-way from

$49
(American Airlines)
Provider with most accurate pricing for Key West-Charleston flight deals.
Search Deals
Provider most trusted by Cheapflights users for Key West-Charleston flights.
Search Deals
From Florida Keys to Charleston
Search Deals
One-way flight from Florida Keys to Charleston
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florida Keys to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 10, 2025.
Use the filters below to find and compare flights from Florida Keys to Charleston that are best for you.

Fly from

Florida Keys

Fly to

Charleston

Route

Depart

Return

Price

MiamiCharleston

MIA - CHS

MIACHS

Miami

Fri 12/5

11:03 pm-12:46 am

Nonstop1h 43m

Charleston

Sun 12/7

6:00 am-7:44 am

Nonstop1h 44m

$97

MiamiCharleston

MIA - CHS

MIACHS

Miami

Mon 12/8

7:03 am-8:45 am

Nonstop1h 42m

Charleston

Mon 12/15

6:00 am-7:44 am

Nonstop1h 44m

$97

MiamiCharleston

MIA - CHS

MIACHS

Miami

Fri 12/26

7:00 am-8:47 am

Nonstop1h 47m

Charleston

Wed 1/14

9:27 am-11:19 am

Nonstop1h 52m

$126

MiamiCharleston

MIA - CHS

MIACHS

Miami

Fri 12/26

10:56 pm-12:45 am

Nonstop1h 49m

Charleston

Tue 12/30

8:07 pm-10:00 pm

Nonstop1h 53m

$131

MiamiCharleston

MIA - CHS

MIACHS

Miami

Tue 11/25

10:19 pm-12:03 am

Nonstop1h 44m

Charleston

Tue 12/2

9:27 am-11:13 am

Nonstop1h 46m

$144

MiamiCharleston

MIA - CHS

MIACHS

Miami

Thu 12/4

6:30 pm-11:50 pm

1 stop5h 20m

Charleston

Mon 12/8

5:25 am-9:27 am

1 stop4h 02m

$157

MiamiCharleston

MIA - CHS

MIACHS

Miami

Fri 12/12

7:00 am-1:23 pm

1 stop6h 23m

Charleston

Sun 12/14

6:31 pm-12:46 am

1 stop6h 15m

$157

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Sun 11/23

8:55 am-8:57 am

1 stop24h 02m

Charleston

Thu 11/27

2:59 pm-8:15 am

1 stop17h 16m

$174

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Thu 12/4

8:55 am-8:57 am

1 stop24h 02m

Charleston

Sun 12/7

2:59 pm-8:15 am

1 stop17h 16m

$177

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Fri 12/5

11:19 am-10:07 am

1 stop22h 48m

Charleston

Mon 12/8

9:23 pm-11:05 am

1 stop13h 42m

$226

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/10

Showing 1-10 of 26 results
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Best time to book a flight from Florida Keys to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from Florida Keys with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florida Keys to Charleston
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Charleston

Get insights into the airlines that provide service to Charleston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charleston. Reviews last updated November 10, 2025.
Get a feel of what it's like to fly with Delta, American Airlines, and Spirit Airlines from Florida Keys to Charleston by reading reviews from past customers. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Crew

8.5

Boarding

8.1

Food

7.3

Entertainment

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Crew

8.5

Boarding

8.1

Food

7.3

Entertainment

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
11,045 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Crew

8.5

Boarding

8.1

Food

7.3

Entertainment

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Spirit Airlines
6.3
Okay
8,136 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Crew

8.5

Boarding

8.1

Food

7.3

Entertainment

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Florida Keys to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Charleston from Florida Keys?

    If you book a flight to Charleston from Florida Keys, you will be flying to Charleston, which is the city’s only airport. Charleston (CHS) is located 10.2 mi from the center of Charleston.

  • How long is the flight from Florida Keys to Charleston?

    American Airlines and Breeze Airways can get you from Florida Keys to Charleston in just under 1h 43m. Your travel time can differ by up to 22h 19m. The distance between Florida Keys and Charleston is about 490 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Florida Keys to Charleston one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $49. However, be on the lookout for offers from Southwest and Breeze Airways, as they are both options that can get you from Florida Keys to Charleston for a low price.

  • Can I find deals for flights from Florida Keys to Charleston that include hotel bookings?

    Yes. In addition to deals on Florida Keys to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florida Keys to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florida Keys to Charleston.

  • Can I find deals for business class flights from Florida Keys to Charleston?

    Yes. Cheapflights offers flight deals from Florida Keys to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Summerville
Santee
Walterboro
Isle of Palms
Mount Pleasant
Edisto Beach

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Top airline flying from Florida Keys to Charleston

Discover the top airline that operate flights from Florida Keys to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 10, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$387Average$658FlexibilityNo cancel feeOn-time71%

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