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Charleston

$73+ Cheap flights from Florida Keys to Charleston (CHS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/24. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — CHS
May 4 — May 111
Mon 5/4
Mon 5/11
1 adult, Economy
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Cheap flight deals from Florida Keys to Charleston

Cheapest flights from Florida Keys to Charleston
Explore the most affordable flight options available from Florida Keys to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 4, 2026.

This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/295:42 pm
MIA
-
CHS
Nonstop1h 55m
American Airlines
Sat 5/211:14 am
CHS
-
MIA
Nonstop1h 45m
American Airlines
Deal found 4/1$157
This Southwest deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1312:10 pm
MIA
-
CHS
1 stop5h 30m
Southwest
Sat 5/1610:55 am
CHS
-
MIA
1 stop6h 05m
Southwest
Deal found 4/2$177
This Kiwi.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1512:07 pm
EYW
-
CHS
1 stop20h 41m
Breeze Airways
Mon 5/189:28 pm
CHS
-
EYW
1 stop15h 06m
Breeze Airways
Deal found 4/1$180
This Southwest deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/297:00 am
MIA
-
CHS
2 stops8h 00m
Southwest
Sat 5/211:15 am
CHS
-
MIA
2 stops10h 50m
Southwest
Deal found 4/2$187
This Kiwi.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/185:30 pm
MIA
-
CHS
1 stop17h 38m
Spirit Airlines
Tue 4/2112:05 pm
CHS
-
MIA
1 stop28h 17m
Spirit Airlines
Deal found 4/1$199
This Kiwi.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/164:22 pm
EYW
-
CHS
1 stop5h 37m
Breeze Airways
Mon 4/208:28 pm
CHS
-
EYW
1 stop15h 53m
Breeze Airways
Deal found 4/1$201
This Kiwi.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:49 pm
MIA
-
CHS
1 stop17h 19m
Spirit Airlines
Tue 4/2112:05 pm
CHS
-
MIA
1 stop28h 17m
Spirit Airlines
Deal found 4/1$204
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/510:59 am
EYW
-
CHS
1 stop21h 39m
Breeze Airways
Sat 10/106:00 am
CHS
-
EYW
1 stop3h 24m
Breeze Airways
Deal found 3/31$207
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1010:15 pm
MIA
-
CHS
Nonstop1h 44m
American Airlines
Sat 6/138:09 pm
CHS
-
MIA
Nonstop1h 46m
American Airlines
Deal found 4/3$207
This Kiwi.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:49 pm
MIA
-
CHS
1 stop17h 19m
Spirit Airlines
Fri 4/2412:03 pm
CHS
-
MIA
1 stop28h 19m
Spirit Airlines
Deal found 4/1$209
This Kiwi.com deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:49 pm
MIA
-
CHS
1 stop17h 19m
Spirit Airlines
Sat 5/92:39 pm
CHS
-
MIA
1 stop22h 25m
Spirit Airlines
Deal found 4/3$215
This Kiwi.com deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:49 pm
MIA
-
CHS
1 stop17h 19m
Spirit Airlines
Fri 5/82:39 pm
CHS
-
MIA
1 stop22h 25m
Spirit Airlines
Deal found 4/3$220

Find flight deals from Florida Keys to Charleston

Keep the following information in mind while searching for Florida Keys to Charleston flight deals. Data was last updated April 4, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$157
(American Airlines)

One-way from

$73
(Kiwi.com)
Provider with most accurate pricing for Key West-Charleston flight deals.
Search Deals
Provider most trusted by Cheapflights users for Key West-Charleston flights.
Search Deals
From Florida Keys to Charleston
Search Deals
One-way flight from Florida Keys to Charleston
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florida Keys to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 4, 2026.
Use the filters below to find and compare flights from Florida Keys to Charleston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MiamiCharleston

MIA - CHS

MIACHS

Miami

Sat 4/25

9:55 am-6:05 pm

1 stop8h 10m

Charleston

Tue 4/28

7:40 am-2:15 pm

1 stop6h 35m

$177

MiamiCharleston

MIA - CHS

MIACHS

Miami

Wed 5/13

7:00 am-3:00 pm

2 stops8h 00m

Charleston

Sat 5/16

12:40 pm-10:05 pm

2 stops9h 25m

$187

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Thu 4/16

4:22 pm-9:59 pm

1 stop5h 37m

Charleston

Mon 4/20

8:28 pm-12:21 pm

1 stop15h 53m

$201

MiamiCharleston

MIA - CHS

MIACHS

Miami

Wed 4/22

7:00 am-3:00 pm

2 stops8h 00m

Charleston

Tue 6/23

2:10 pm-10:10 pm

2 stops8h 00m

$247

MiamiCharleston

MIA - CHS

MIACHS

Miami

Sat 4/25

9:55 am-6:05 pm

1 stop8h 10m

Charleston

Mon 4/27

4:45 pm-11:00 pm

1 stop6h 15m

$258

MiamiCharleston

MIA - CHS

MIACHS

Miami

Sat 5/16

9:55 am-6:05 pm

1 stop8h 10m

Charleston

Sat 5/23

8:00 am-7:40 pm

1 stop11h 40m

$302

MiamiCharleston

MIA - CHS

MIACHS

Miami

Tue 4/28

7:00 am-3:00 pm

2 stops8h 00m

Charleston

Thu 4/30

6:00 am-4:50 pm

2 stops10h 50m

$316
Quickest round-trip

MiamiCharleston

MIA - CHS

MIACHS

Miami

Fri 5/8

8:45 am-10:34 am

Nonstop1h 49m

Charleston

Sun 5/10

6:00 am-7:40 am

Nonstop1h 40m

$327

MiamiCharleston

MIA - CHS

MIACHS

Miami

Thu 8/20

7:15 am-4:40 pm

2 stops9h 25m

Charleston

Tue 8/25

8:10 am-1:35 pm

1 stop5h 25m

$327

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Fri 4/24

6:22 pm-7:04 pm

1 stop24h 42m

Charleston

Mon 4/27

5:15 pm-3:57 pm

1 stop22h 42m

$706

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/3

Showing 1-10 of 31 resultsSorted by cheapest first
1
2
3
4

Best time to book a flight from Florida Keys to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from Florida Keys with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florida Keys to Charleston
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Charleston

Get insights into the airlines that provide service to Charleston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charleston. Reviews last updated April 4, 2026.
Get a feel of what it's like to fly with American Airlines and Spirit Airlines from Florida Keys to Charleston by reading reviews from past customers. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,556 reviews

Entertainment

6.9

Food

6.4

Boarding

7.5

Crew

7.9

Comfort

7.2

Overall

7.1

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes
American Airlines
7.1
Good
11,556 reviews
American Airlines
7.1
Good
11,556 reviews

Entertainment

6.9

Food

6.4

Boarding

7.5

Crew

7.9

Comfort

7.2

Overall

7.1

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes
Spirit Airlines
6.3
Okay
8,583 reviews
American Airlines
7.1
Good
11,556 reviews

Entertainment

6.9

Food

6.4

Boarding

7.5

Crew

7.9

Comfort

7.2

Overall

7.1

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes

Related info for your journey

Find useful and relevant information for your journey from Florida Keys to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Charleston from Florida Keys?

    If you book a flight to Charleston from Florida Keys, you will be flying to Charleston, which is the city’s only airport. Charleston (CHS) is located 10.2 mi from the center of Charleston.

  • How long is the flight from Florida Keys to Charleston?

    Breeze Airways and Southwest can get you from Florida Keys to Charleston in just under 5h 37m. Your travel time can differ by up to 5h 08m. The distance between Florida Keys and Charleston is about 585 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Florida Keys to Charleston one-way?

    The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $36. However, be on the lookout for offers from JetBlue and American Airlines, as they are both options that can get you from Florida Keys to Charleston for a low price.

  • Can I find deals for flights from Florida Keys to Charleston that include hotel bookings?

    Yes. In addition to deals on Florida Keys to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florida Keys to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florida Keys to Charleston.

  • Can I find deals for business class flights from Florida Keys to Charleston?

    Yes. Cheapflights offers flight deals from Florida Keys to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Santee
Summerville
Walterboro
Isle of Palms
Mount Pleasant
Goose Creek
Edisto Beach

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