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Charleston

$70+ Cheap flights from Florida Keys to Charleston (CHS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/26. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — CHS
Mar 14 — Mar 211
Sat 3/14
Sat 3/21
1 adult, Economy
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Cheap flight deals from Florida Keys to Charleston

Cheapest flights from Florida Keys to Charleston
Explore the most affordable flight options available from Florida Keys to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 12, 2026.

This Mytrip deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/116:02 am
MIA
-
CHS
1 stop10h 03m
Spirit Airlines
Wed 3/1812:04 pm
CHS
-
MIA
1 stop11h 35m
Spirit Airlines
Deal found 2/9$139
This Mytrip deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/116:02 am
MIA
-
CHS
1 stop10h 03m
Spirit Airlines
Wed 5/69:35 am
CHS
-
MIA
1 stop13h 24m
Spirit Airlines
Deal found 2/11$140
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/117:00 am
MIA
-
CHS
1 stop9h 05m
Multiple Airlines
Wed 3/1812:04 pm
CHS
-
MIA
2 stops12h 43m
Multiple Airlines
Deal found 2/9$164
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2611:01 am
EYW
-
CHS
1 stop10h 58m
Breeze Airways
Mon 3/28:28 pm
CHS
-
EYW
1 stop15h 53m
Breeze Airways
Deal found 2/11$168
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:02 am
MIA
-
CHS
1 stop10h 03m
Multiple Airlines
Sat 3/75:00 pm
CHS
-
MIA
1 stop9h 09m
Multiple Airlines
Deal found 2/9$169
This Mytrip deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:02 am
MIA
-
CHS
1 stop10h 03m
Spirit Airlines
Sat 2/285:00 pm
CHS
-
MIA
2 stops19h 16m
Spirit Airlines
Deal found 2/9$179
This Kiwi.com deal was found by Cheapflights users on 2/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/57:09 pm
MIA
-
CHS
2 stops44h 56m
Multiple Airlines
Mon 3/1612:04 pm
CHS
-
MIA
1 stop7h 12m
Multiple Airlines
Deal found 2/12$184
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/117:00 am
MIA
-
CHS
1 stop9h 05m
Multiple Airlines
Wed 5/63:26 pm
CHS
-
MIA
2 stops18h 51m
Multiple Airlines
Deal found 2/11$186
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/285:05 am
MIA
-
CHS
2 stops12h 35m
Multiple Airlines
Tue 3/35:00 pm
CHS
-
MIA
1 stop27h 13m
Multiple Airlines
Deal found 2/9$187
This CheapOair deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/512:52 pm
MIA
-
CHS
1 stop27h 13m
Spirit Airlines
Sat 3/75:00 pm
CHS
-
MIA
1 stop26h 13m
Spirit Airlines
Deal found 2/8$193
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/176:00 am
MIA
-
CHS
1 stop9h 55m
Multiple Airlines
Tue 3/105:00 pm
CHS
-
MIA
1 stop9h 09m
Multiple Airlines
Deal found 2/9$194
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/2412:10 pm
EYW
-
CHS
1 stop20h 38m
Breeze Airways
Mon 7/279:28 pm
CHS
-
EYW
1 stop15h 06m
Breeze Airways
Deal found 2/11$322

Find flight deals from Florida Keys to Charleston

Keep the following information in mind while searching for Florida Keys to Charleston flight deals. Data was last updated February 12, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$139
(Mytrip)

One-way from

$70
(Breeze Airways)
Provider with most accurate pricing for Key West-Charleston flight deals.
Search Deals
Provider most trusted by Cheapflights users for Key West-Charleston flights.
Search Deals
From Florida Keys to Charleston
Search Deals
One-way flight from Florida Keys to Charleston
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florida Keys to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 12, 2026.
Use the filters below to find and compare flights from Florida Keys to Charleston that are best for you.

Fly from

Florida Keys

Fly to

Charleston

Route

Depart

Return

Price

MiamiCharleston

MIA - CHS

MIACHS

Miami

Wed 3/11

6:02 am-4:05 pm

1 stop10h 03m

Charleston

Wed 5/6

9:35 am-10:59 pm

1 stop13h 24m

$140

Key WestCharleston

EYW - CHS

EYWCHS

Key West

Thu 2/26

11:01 am-9:59 pm

1 stop10h 58m

Charleston

Mon 3/2

8:28 pm-12:21 pm

1 stop15h 53m

$168

MiamiCharleston

MIA - CHS

MIACHS

Miami

Thu 3/5

12:52 pm-4:05 pm

1 stop27h 13m

Charleston

Sat 3/7

5:00 pm-7:13 pm

1 stop26h 13m

$193

MiamiCharleston

MIA - CHS

MIACHS

Miami

Wed 3/11

10:00 pm-11:59 pm

Nonstop1h 59m

Charleston

Wed 5/6

11:14 am-12:59 pm

Nonstop1h 45m

$209

MiamiCharleston

MIA - CHS

MIACHS

Miami

Thu 3/5

12:52 pm-4:05 pm

1 stop27h 13m

Charleston

Mon 3/16

12:04 pm-7:16 pm

1 stop7h 12m

$213

MiamiCharleston

MIA - CHS

MIACHS

Miami

Wed 3/4

12:52 pm-4:05 pm

1 stop27h 13m

Charleston

Sun 3/8

9:36 pm-8:04 am

1 stop10h 28m

$224

MiamiCharleston

MIA - CHS

MIACHS

Miami

Tue 3/3

9:53 pm-4:05 pm

2 stops18h 12m

Charleston

Fri 3/6

6:35 pm-11:59 pm

2 stops29h 24m

$234

MiamiCharleston

MIA - CHS

MIACHS

Miami

Fri 3/13

11:38 am-11:09 am

1 stop23h 31m

Charleston

Fri 3/20

12:04 pm-12:47 am

2 stops12h 43m

$236

MiamiCharleston

MIA - CHS

MIACHS

Miami

Wed 3/18

5:05 am-10:13 pm

2 stops17h 08m

Charleston

Tue 3/31

12:04 pm-7:16 pm

1 stop7h 12m

$239

MiamiCharleston

MIA - CHS

MIACHS

Miami

Wed 3/18

8:30 am-10:26 am

Nonstop1h 56m

Charleston

Tue 3/31

3:54 pm-8:18 pm

1 stop4h 24m

$244

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/11

Showing 1-10 of 42 results
1
2
3
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5

Best time to book a flight from Florida Keys to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from Florida Keys with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florida Keys to Charleston
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Charleston

Get insights into the airlines that provide service to Charleston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charleston. Reviews last updated February 12, 2026.
Get a feel of what it's like to fly with American Airlines and Spirit Airlines from Florida Keys to Charleston by reading reviews from past customers. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,277 reviews

Food

6.4

Overall

7.2

Entertainment

6.9

Crew

8.0

Comfort

7.2

Boarding

7.5

Reviews

1 / 20
4.0
Okay

Susie,Jan 2026

TPA - CLT

I was sitting at the back of the plane and the flight attendants were so loud, talking to each other and laughing! I thought they were having a party back there.
American Airlines
7.2
Good
11,277 reviews
American Airlines
7.2
Good
11,277 reviews

Food

6.4

Overall

7.2

Entertainment

6.9

Crew

8.0

Comfort

7.2

Boarding

7.5

Reviews

1 / 20
4.0
Okay

Susie,Jan 2026

TPA - CLT

I was sitting at the back of the plane and the flight attendants were so loud, talking to each other and laughing! I thought they were having a party back there.
Spirit Airlines
6.3
Okay
8,451 reviews
American Airlines
7.2
Good
11,277 reviews

Food

6.4

Overall

7.2

Entertainment

6.9

Crew

8.0

Comfort

7.2

Boarding

7.5

Reviews

1 / 20
4.0
Okay

Susie,Jan 2026

TPA - CLT

I was sitting at the back of the plane and the flight attendants were so loud, talking to each other and laughing! I thought they were having a party back there.

Related info for your journey

Find useful and relevant information for your journey from Florida Keys to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Charleston from Florida Keys?

    If you book a flight to Charleston from Florida Keys, you will be flying to Charleston, which is the city’s only airport. Charleston (CHS) is located 10.2 mi from the center of Charleston.

  • How long is the flight from Florida Keys to Charleston?

    Spirit Airlines, Breeze Airways, and American Airlines can get you from Florida Keys to Charleston in just under 1h 59m. Your travel time can differ by up to 8h 59m. The distance between Florida Keys and Charleston is about 490 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Florida Keys to Charleston one-way?

    The cheapest airline one-way is Spirit Airlines, with whom users have recently found tickets for as low as $31. However, be on the lookout for offers from American Airlines and Breeze Airways, as they are both options that can get you from Florida Keys to Charleston for a low price.

  • Can I find deals for flights from Florida Keys to Charleston that include hotel bookings?

    Yes. In addition to deals on Florida Keys to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florida Keys to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florida Keys to Charleston.

  • Can I find deals for business class flights from Florida Keys to Charleston?

    Yes. Cheapflights offers flight deals from Florida Keys to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Santee
Summerville
Walterboro
Isle of Palms
Mount Pleasant
Edisto Beach

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