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Charleston

$59+ Cheap flights from Florida Keys to Charleston (CHS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/18. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — CHS
Oct 24 — Oct 311
Fri 10/24
Fri 10/31
1 adult, Economy
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Cheap flight deals from Florida Keys to Charleston

Keep the following information in mind while searching for Florida Keys to Charleston flight deals. Data was last updated September 24, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$117
(American Airlines)

One-way from

$59
(American Airlines)

Popular in

February

Cheapest in

September

Average price

$198
Provider with most accurate pricing for Key West-Charleston flight deals.
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Provider most trusted by Cheapflights users for Key West-Charleston flights.
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From Florida Keys to Charleston
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One-way flight from Florida Keys to Charleston
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Highest demand for flights based on searches. 25% potential increase in price ($196 potential increase over avg. RT price).
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Cheapest flight prices on average. 12% potential price decrease ($65 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Florida Keys to Charleston

Cheapest flights from Florida Keys to Charleston
Explore the most affordable flight options available from Florida Keys to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 24, 2025.

This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/710:15 pmMIA - CHS
Nonstop1h 44mAmerican Airlines
Wed 10/87:44 pmCHS - MIA
Nonstop1h 42mAmerican Airlines
Deal found 9/24$117
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/610:15 pmMIA - CHS
Nonstop1h 44mAmerican Airlines
Wed 10/229:42 amCHS - MIA
Nonstop1h 38mAmerican Airlines
Deal found 9/24$120
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/217:01 amMIA - CHS
Nonstop1h 42mAmerican Airlines
Sun 11/237:56 pmCHS - MIA
Nonstop1h 42mAmerican Airlines
Deal found 9/23$125
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2310:19 pmMIA - CHS
Nonstop1h 44mAmerican Airlines
Fri 11/286:00 amCHS - MIA
Nonstop1h 38mAmerican Airlines
Deal found 9/24$128
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/227:10 amMIA - CHS
Nonstop1h 51mAmerican Airlines
Fri 11/286:00 amCHS - MIA
Nonstop1h 38mAmerican Airlines
Deal found 9/24$130
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/267:01 amMIA - CHS
Nonstop1h 42mAmerican Airlines
Wed 11/267:56 pmCHS - MIA
Nonstop1h 42mAmerican Airlines
Deal found 9/24$139
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2710:15 pmMIA - CHS
Nonstop1h 44mAmerican Airlines
Mon 11/37:57 pmCHS - MIA
Nonstop1h 42mAmerican Airlines
Deal found 9/22$157
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/249:49 amMIA - CHS
1 stop10h 26mSpirit Airlines
Mon 10/279:10 pmCHS - MIA
1 stop26h 00mSpirit Airlines
Deal found 9/24$160
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/169:49 amMIA - CHS
2 stops23h 17mSpirit Airlines
Mon 10/209:10 pmCHS - MIA
1 stop26h 00mSpirit Airlines
Deal found 9/24$161
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/179:49 amMIA - CHS
1 stop10h 26mSpirit Airlines
Mon 10/209:10 pmCHS - MIA
1 stop26h 00mSpirit Airlines
Deal found 9/23$164
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/66:00 amMIA - CHS
1 stop4h 08mDelta
Tue 12/910:40 amCHS - MIA
1 stop6h 45mDelta
Deal found 9/23$167
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/229:49 amMIA - CHS
1 stop8h 52mSpirit Airlines
Wed 10/297:55 pmCHS - MIA
1 stop27h 15mSpirit Airlines
Deal found 9/23$171

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florida Keys to Charleston that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 24, 2025.
Use the filters below to find and compare flights from Florida Keys to Charleston that are best for you.

Fly from

Florida Keys

Fly to

Charleston

Route

Depart

Return

Price

MiamiCharleston

MIA - CHS

MIACHS

Miami

Fri 10/10

10:15 pm-11:59 pm

Nonstop1h 44m

Charleston

Sat 10/11

7:44 pm-9:26 pm

Nonstop1h 42m

$117

MiamiCharleston

MIA - CHS

MIACHS

Miami

Tue 10/28

10:15 pm-11:59 pm

Nonstop1h 44m

Charleston

Mon 11/3

7:57 pm-9:39 pm

Nonstop1h 42m

$117

MiamiCharleston

MIA - CHS

MIACHS

Miami

Mon 10/27

7:18 am-9:01 am

Nonstop1h 43m

Charleston

Mon 11/3

6:00 am-7:38 am

Nonstop1h 38m

$117

MiamiCharleston

MIA - CHS

MIACHS

Miami

Tue 10/7

5:22 pm-7:04 pm

Nonstop1h 42m

Charleston

Wed 10/8

6:00 am-7:37 am

Nonstop1h 37m

$117

MiamiCharleston

MIA - CHS

MIACHS

Miami

Wed 10/22

9:49 am-6:41 pm

1 stop8h 52m

Charleston

Wed 10/29

7:55 pm-11:10 pm

1 stop27h 15m

$171

MiamiCharleston

MIA - CHS

MIACHS

Miami

Tue 10/14

6:00 am-10:20 am

1 stop4h 20m

Charleston

Fri 10/17

8:03 pm-12:29 am

1 stop4h 26m

$177

MiamiCharleston

MIA - CHS

MIACHS

Miami

Mon 10/27

6:00 am-10:20 am

1 stop4h 20m

Charleston

Mon 11/3

7:05 pm-12:29 am

1 stop5h 24m

$177

MiamiCharleston

MIA - CHS

MIACHS

Miami

Tue 10/21

9:49 am-6:41 pm

1 stop8h 52m

Charleston

Thu 10/23

6:45 am-4:03 pm

2 stops9h 18m

$181

MiamiCharleston

MIA - CHS

MIACHS

Miami

Tue 10/7

7:10 am-1:25 pm

1 stop6h 15m

Charleston

Wed 10/8

5:35 am-9:35 am

1 stop4h 00m

$187

MiamiCharleston

MIA - CHS

MIACHS

Miami

Mon 10/6

12:09 pm-6:58 pm

1 stop6h 49m

Charleston

Wed 10/22

5:35 am-9:35 am

1 stop4h 00m

$187

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/24

Showing 1-10 of 32 results
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2
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Best time to book a flight from Florida Keys to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from Florida Keys with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florida Keys to Charleston
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Charleston

Get insights into the airlines that provide service to Charleston. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Charleston. Reviews last updated September 24, 2025.
Get a feel of what it's like to fly with Delta, American Airlines, and JetBlue from Florida Keys to Charleston by reading reviews from past customers. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,973 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
8.0
Very good
7,973 reviews
Delta
8.0
Very good
7,973 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,973 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
JetBlue
7.2
Good
2,913 reviews
Delta
8.0
Very good
7,973 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Spirit Airlines
6.3
Okay
8,042 reviews
Delta
8.0
Very good
7,973 reviews

Boarding

8.2

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Florida Keys to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Charleston from Florida Keys?

    If you book a flight to Charleston from Florida Keys, you will be flying to Charleston, which is the city’s only airport. Charleston (CHS) is located 10.2 mi from the center of Charleston.

  • How long is the flight from Florida Keys to Charleston?

    American Airlines can get you from Florida Keys to Charleston in just under 1h 44m. Your travel time will be generally consistent. The distance between Florida Keys and Charleston is about 490 mi. Generally, flights for this route are nonstop.

  • Can I find deals for flights from Florida Keys to Charleston that include hotel bookings?

    Yes. In addition to deals on Florida Keys to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florida Keys to Charleston?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florida Keys to Charleston.

  • Can I find deals for business class flights from Florida Keys to Charleston?

    Yes. Cheapflights offers flight deals from Florida Keys to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florida Keys to Charleston?

    Currently, August is the cheapest month in which you can book a flight from Florida Keys to Charleston (average of $217). Flying from Florida Keys to Charleston in March is currently the most expensive (average of $335). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Charleston?

Book flights to Charleston if you plan to visit one of these locations
North Charleston
Summerville
Walterboro
Mount Pleasant
Isle of Palms
Santee
Edisto Beach

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Florida Keys to Charleston

Discover the top airline that operate flights from Florida Keys to Charleston. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 24, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$492Average$658FlexibilityNo cancel feeOn-time71%

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