$58+ Cheap flights from Charleston (CHS) to Florida Keys
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/24. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — EYW
Sep 24 — Oct 11
Round-trip
1 adult, Economy
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Find cheap flights from Charleston to Florida Keys with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Charleston to Florida Keys
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Cheapest flights from Charleston to Florida KeysExplore the most affordable flight options available from Charleston to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 25, 2026.
Explore the most affordable flight options available from Charleston to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 25, 2026.
This Breeze Airways deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am -
1 stop3h 24m
Wed 9/1610:04 am -
1 stop3h 20m
Deal found 8/24![Breeze Airways logo]()
$82
This Kiwi.com deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:00 am -
1 stop3h 24m
Wed 9/1610:04 am -
1 stop3h 20m
Deal found 8/22![Breeze Airways logo]()
$84
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:00 am -
1 stop3h 24m
Wed 9/2310:04 am -
1 stop3h 20m
Deal found 8/21![Breeze Airways logo]()
$97
This Kiwi.com deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:00 am -
1 stop3h 24m
Sat 9/1910:04 am -
1 stop3h 20m
Deal found 8/22![Breeze Airways logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am -
1 stop3h 24m
Fri 9/1812:59 pm -
1 stop24h 25m
Deal found 8/20![Breeze Airways logo]()
$105
This Kiwi.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:00 am -
1 stop3h 24m
Fri 9/1812:59 pm -
1 stop24h 25m
Deal found 8/20![Breeze Airways logo]()
$106
This Breeze Airways deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am -
1 stop3h 24m
Sat 9/1210:04 am -
1 stop3h 20m
Deal found 8/20![Breeze Airways logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am -
1 stop3h 24m
Mon 9/1410:59 am -
1 stop21h 39m
Deal found 8/22![Breeze Airways logo]()
$112
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:00 am -
Nonstop1h 44m
Sat 10/39:50 pm -
Nonstop1h 53m
Deal found 8/21![American Airlines logo]()
$267
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/611:12 am -
Nonstop1h 43m
Tue 10/138:45 am -
Nonstop1h 47m
Deal found 8/24![American Airlines logo]()
$269
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/234:30 pm -
Nonstop1h 45m
Wed 9/307:45 pm -
Nonstop1h 51m
Deal found 8/24![American Airlines logo]()
$271
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1311:12 am -
Nonstop1h 43m
Sat 10/1710:14 pm -
Nonstop1h 45m
Deal found 8/21![American Airlines logo]()
$273
Best flights from Charleston to Florida KeysDiscover carefully curated flight deals from Charleston to Florida Keys that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 25, 2026.
Discover carefully curated flight deals from Charleston to Florida Keys that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:00 am -
1 stop3h 24m
Wed 9/1610:04 am -
1 stop3h 20m
Deal found 8/23![Breeze Airways logo]()
$102
This Breeze Airways deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:00 am -
1 stop3h 24m
Wed 9/2310:04 am -
1 stop3h 20m
Deal found 8/24![Breeze Airways logo]()
$111
This Delta deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/65:30 am -
1 stop5h 30m
Tue 10/136:04 am -
1 stop4h 06m
Deal found 8/24![Delta logo]()
$287
This Breeze Airways deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:00 am -
1 stop3h 24m
Wed 11/1110:04 am -
1 stop3h 20m
Deal found 8/21![Breeze Airways logo]()
$132
This Southwest deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:40 am -
1 stop4h 45m
Tue 10/136:45 am -
2 stops9h 55m
Deal found 8/22![Southwest logo]()
$307
This Breeze Airways deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:00 am -
1 stop3h 24m
Thu 9/2410:59 am -
1 stop20h 26m
Deal found 8/22![Breeze Airways logo]()
$140
This Breeze Airways deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:00 am -
1 stop3h 24m
Sat 10/3110:04 am -
1 stop3h 20m
Deal found 8/20![Breeze Airways logo]()
$149
This Breeze Airways deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:00 am -
1 stop3h 24m
Thu 10/110:59 am -
1 stop21h 49m
Deal found 8/20![Breeze Airways logo]()
$153
This Breeze Airways deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:00 am -
1 stop3h 24m
Tue 10/271:16 pm -
1 stop24h 08m
Deal found 8/21![Breeze Airways logo]()
$165
This Delta deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/192:32 pm -
1 stop6h 38m
Sat 9/267:21 am -
1 stop6h 06m
Deal found 8/24![Delta logo]()
$287
This Breeze Airways deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/188:58 pm -
1 stop12h 26m
Mon 9/2112:59 pm -
1 stop23h 32m
Deal found 8/24![Breeze Airways logo]()
$169
This Southwest deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/171:30 pm -
2 stops8h 40m
Fri 11/206:50 am -
1 stop9h 00m
Deal found 8/22![Southwest logo]()
$307
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/144:20 pm -
1 stop6h 21m
Fri 10/167:36 pm -
1 stop4h 23m
Deal found 8/20![Delta logo]()
$302
This Southwest deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2110:50 am -
2 stops10h 45m
Sat 10/316:25 am -
2 stops9h 15m
Deal found 8/23![Southwest logo]()
$312
This Southwest deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/71:55 pm -
2 stops8h 15m
Wed 10/1412:05 pm -
1 stop8h 15m
Deal found 8/22![Southwest logo]()
$313
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:35 pm -
1 stop5h 04m
Wed 9/234:35 pm -
1 stop4h 09m
Deal found 8/20![Delta logo]()
$333
This Southwest deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/14:45 pm -
1 stop5h 50m
Mon 10/57:10 am -
2 stops9h 00m
Deal found 8/24![Southwest logo]()
$322
This Southwest deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/308:10 am -
2 stops11h 55m
Sat 10/37:00 am -
2 stops9h 30m
Deal found 8/23![Southwest logo]()
$332
This Breeze Airways deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/129:39 pm -
1 stop14h 40m
Mon 11/1612:59 pm -
1 stop23h 32m
Deal found 8/21![Breeze Airways logo]()
$268
Last-minute flights from Charleston to Florida KeysDiscover last-minute flight deals from Charleston to Florida Keys. Data last updated August 25, 2026 and is based on user searches.
Discover last-minute flight deals from Charleston to Florida Keys. Data last updated August 25, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:00 am -
Nonstop1h 40m
Sat 9/510:15 pm -
Nonstop1h 44m
Deal found 8/24![American Airlines logo]()
$427
This Delta deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/291:13 pm -
1 stop5h 29m
Mon 8/316:00 am -
1 stop5h 54m
Deal found 8/24![Delta logo]()
$463
This Southwest deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:35 am -
1 stop5h 50m
Sun 9/612:40 pm -
1 stop8h 10m
Deal found 8/23![Southwest logo]()
$407
This Southwest deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:35 am -
1 stop5h 50m
Sat 9/59:40 am -
2 stops9h 15m
Deal found 8/23![Southwest logo]()
$412
This Breeze Airways deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am -
1 stop3h 24m
Wed 9/1610:04 am -
1 stop3h 20m
Deal found 8/24![Breeze Airways logo]()
$82
This Kiwi.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am -
1 stop3h 24m
Fri 9/1812:59 pm -
1 stop24h 25m
Deal found 8/20![Breeze Airways logo]()
$105
This Breeze Airways deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am -
1 stop3h 24m
Sat 9/1210:04 am -
1 stop3h 20m
Deal found 8/20![Breeze Airways logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am -
1 stop3h 24m
Mon 9/1410:59 am -
1 stop21h 39m
Deal found 8/22![Breeze Airways logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:00 am -
1 stop3h 24m
Wed 9/1610:04 am -
1 stop3h 20m
Deal found 8/22![Breeze Airways logo]()
$84
This Kiwi.com deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:00 am -
1 stop3h 24m
Sat 9/1910:04 am -
1 stop3h 20m
Deal found 8/22![Breeze Airways logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:00 am -
1 stop3h 24m
Fri 9/1812:59 pm -
1 stop24h 25m
Deal found 8/20![Breeze Airways logo]()
$106
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:00 am -
1 stop3h 24m
Wed 9/2310:04 am -
1 stop3h 20m
Deal found 8/21![Breeze Airways logo]()
$97
One-way flights from Charleston to Florida KeysSearch for one-way flight options from Charleston to Florida Keys. Find affordable one-way fares based on user searches. Data last updated August 25, 2026.
Search for one-way flight options from Charleston to Florida Keys. Find affordable one-way fares based on user searches. Data last updated August 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:00 am -
1 stop3h 24m
Deal found 8/21![Breeze Airways logo]()
$58
This Breeze Airways deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:00 am -
1 stop3h 24m
Deal found 8/21![Breeze Airways logo]()
$67
This Kiwi.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am -
1 stop3h 24m
Deal found 8/23![Breeze Airways logo]()
$69
This Kiwi.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/118:58 pm -
1 stop12h 26m
Deal found 8/23![Breeze Airways logo]()
$95
This Kiwi.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:00 am -
2 stops14h 38m
Deal found 8/23![Multiple Airlines logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/159:18 am -
2 stops11h 20m
Deal found 8/24![Multiple Airlines logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/223:00 pm -
2 stops29h 38m
Deal found 8/24![Multiple Airlines logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/201:13 pm -
2 stops21h 02m
Deal found 8/22![Multiple Airlines logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:00 am -
2 stops15h 29m
Deal found 8/21![Multiple Airlines logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:00 am -
2 stops14h 38m
Deal found 8/21![Multiple Airlines logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/183:27 pm -
2 stops29h 11m
Deal found 8/19![Multiple Airlines logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/113:27 pm -
2 stops29h 11m
Deal found 8/21![Multiple Airlines logo]()
$124
Find flight deals from Charleston to Florida Keys
Keep the following information in mind while searching for Charleston to Florida Keys flight deals. Data was last updated August 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $82 (Breeze Airways) |
One-way from | $58 (Kiwi.com) |
Popular in | April |
Cheapest in | September |
Average price | $332 |
Cheapflights Fare Finder
Customize your flight search to find flights from Charleston to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 25, 2026.
Use the filters below to find and compare flights from Charleston to Florida Keys that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
CharlestonKey West
CHS Charleston - EYW Key West
CHSEYW
Charleston
Sat 9/12
6:00 am-9:24 am
1 stop3h 24m
Key West
Wed 9/16
10:04 am-1:24 pm
1 stop3h 20m
$102
CharlestonKey West
CHS Charleston - EYW Key West
CHSEYW
Charleston
Sat 9/19
6:00 am-9:24 am
1 stop3h 24m
Key West
Wed 9/23
10:04 am-1:24 pm
1 stop3h 20m
$111
CharlestonKey West
CHS Charleston - EYW Key West
CHSEYW
Charleston
Sat 11/7
6:00 am-9:24 am
1 stop3h 24m
Key West
Wed 11/11
10:04 am-1:24 pm
1 stop3h 20m
$132
CharlestonKey West
CHS Charleston - EYW Key West
CHSEYW
Charleston
Sat 9/19
6:00 am-9:24 am
1 stop3h 24m
Key West
Thu 9/24
10:59 am-7:25 am
1 stop20h 26m
$140
CharlestonKey West
CHS Charleston - EYW Key West
CHSEYW
Charleston
Sat 10/24
6:00 am-9:24 am
1 stop3h 24m
Key West
Sat 10/31
10:04 am-1:24 pm
1 stop3h 20m
$149
CharlestonKey West
CHS Charleston - EYW Key West
CHSEYW
Charleston
Sat 9/26
6:00 am-9:24 am
1 stop3h 24m
Key West
Thu 10/1
10:59 am-8:48 am
1 stop21h 49m
$153
CharlestonKey West
CHS Charleston - EYW Key West
CHSEYW
Charleston
Sat 10/24
6:00 am-9:24 am
1 stop3h 24m
Key West
Tue 10/27
1:16 pm-1:24 pm
1 stop24h 08m
$165
CharlestonKey West
CHS Charleston - EYW Key West
CHSEYW
Charleston
Fri 9/18
8:58 pm-9:24 am
1 stop12h 26m
Key West
Mon 9/21
12:59 pm-12:31 pm
1 stop23h 32m
$169
CharlestonKey West
CHS Charleston - EYW Key West
CHSEYW
Charleston
Thu 11/12
9:39 pm-12:19 pm
1 stop14h 40m
Key West
Mon 11/16
12:59 pm-12:31 pm
1 stop23h 32m
$268
CharlestonMiami
CHS Charleston - MIA Miami
CHSMIA
Charleston
Tue 10/6
5:30 am-11:00 am
1 stop5h 30m
Miami
Tue 10/13
6:04 am-10:10 am
1 stop4h 06m
$287
Showing 1-10 of 36 resultsSorted by cheapest first
Best time to book a flight from Charleston to Florida Keys
Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Charleston with our price prediction graph.
CHS-EYW
CHS-MIA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Charleston to Florida Keys
CHS-zzEOA
CHS-EYW
CHS-MIA
What is the cheapest month to book a flight from Charleston to Florida Keys?
Currently, September is the cheapest month in which you can book a flight from Charleston to Florida Keys (average of $255). Flying from Charleston to Florida Keys in April is currently the most expensive (average of $414). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from Charleston to Florida Keys?
The best time to book flights from Charleston to Florida Keys is 87 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
Reviews of airlines servicing Florida Keys
Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated August 25, 2026.
Read reviews from past customers who have flown Breeze Airways,Delta, andAmerican Airlines from Charleston to Florida Keys. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.7
Food
6.7
Crew
8.8
Comfort
8.2
Boarding
8.3
Overall
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Entertainment
6.7
Food
6.7
Crew
8.8
Comfort
8.2
Boarding
8.3
Overall
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Entertainment
6.7
Food
6.7
Crew
8.8
Comfort
8.2
Boarding
8.3
Overall
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Entertainment
6.7
Food
6.7
Crew
8.8
Comfort
8.2
Boarding
8.3
Overall
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Entertainment
6.7
Food
6.7
Crew
8.8
Comfort
8.2
Boarding
8.3
Overall
8.2
Reviews
1 / 18
4.0
OkayLisa,Mar 2026
ORF - JAX
Related info for your journey
Find useful and relevant information for your journey from Charleston to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Charleston to Florida Keys
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Florida Keys by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Charleston to Florida Keys by cabin class
Find flights from Charleston to Florida Keys, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Charleston and Florida Keys flights
Browse other Charleston and Florida Keys flight options. Last updated on August 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Charleston to Florida Keys
Discover the top 3 airlines that operate flights from Charleston to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$124 | Average$211 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$327 | Average$478 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$344 | Average$515 | FlexibilityNo cancel fee | On-timeN/A |