What’s the fastest layover option from St. Louis to Charleston?

Flights via Nashville (BNA) have the shortest average one-way travel time for 1-stop routes: 4h 45m.

What’s the cheapest layover airport for flights from St. Louis to Charleston?

Nashville (BNA) is the most affordable 1-stop option, with an average round-trip price of $326.

Which airport typically offers the quickest layover for flights from St. Louis to Charleston?

Flights via Chicago (ORD) offer the fastest connection on this route, with an average layover time of 1h 09m.

What’s the top layover airport for flights from St. Louis to Charleston?

Chicago (ORD) – chosen by Cheapflights users on 50% of 1-stop itineraries from St. Louis to Charleston on Cheapflights.

How popular is this St. Louis to Charleston flight route?

Flights from Lambert-St Louis to Charleston have been viewed 6 times in the past calendar month.

What are the cheapest airlines flying from St. Louis to Charleston round-trip?

Cheapflights users have booked flights from St. Louis to Charleston round-trip from $208. Other airlines that can offer you cheap pricing are American Airlines, from $275, and Southwest, from $286. These flights start at 46% lower than the current average price 3 months from now.

In terms of precipitation, rainfall in Charleston ranges from 2.4 - 7.2 inches per month. August is typically the wettest month, when rainfall can reach 7.2 in. November is typically the driest time to visit Charleston when rainfall is around 2.4 in.

If weather is an important factor for your trip to Charleston, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 82.4 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 48.2 F).

What are the most popular airlines that fly from St. Louis to Charleston?

When booking a flight from St. Louis to Charleston, you may want to consider flying on American Airlines, Southwest or Delta as they are the most popular for this route.

Most accurate provider : When it comes to deals on St. Louis-Charleston flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on St. Louis-Charleston flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from St. Louis-Charleston flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on St. Louis-Charleston flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Charleston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from St. Louis to Charleston that include hotel bookings?

Yes. In addition to deals on St. Louis to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from St. Louis to Charleston?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Charleston.

Can I find deals for business class flights from St. Louis to Charleston?

Yes. Cheapflights offers flight deals from St. Louis to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$78+ Flights from St. Louis to Charleston

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from St. Louis to Charleston with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Lambert-St Louis to Charleston are usually found in August or October, booked 49 days in advance, depart on a Monday or Tuesday and return on a Thursday

Cheap flight deals from St. Louis to Charleston

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$193 (Kiwi.com)
One-way from	$78 (Kiwi.com)
Popular in	May
Cheapest in	August
Average price	$392

Provider with most accurate pricing for Lambert-St Louis-Charleston flight deals.

Search Deals

Provider most trusted by Cheapflights users for Lambert-St Louis-Charleston flights.

Search Deals

From Lambert-St Louis to Charleston

Search Deals

One-way flight from Lambert-St Louis to Charleston

Search Deals

Highest demand for flights based on searches. 3% potential increase in price ($16 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in November 2025

Search Deals

Find flight deals from St. Louis to Charleston

Cheapest flights from St. Louis to Charleston
Explore the most affordable flight options available from St. Louis to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 8, 2025.

Mon 12/14:13 pmSTL - CHS

1 stop15h 24mMultiple Airlines

Wed 12/36:15 pmCHS - STL

2 stops17h 52mMultiple Airlines

Deal found 11/7

$193

Mon 12/87:43 pmSTL - CHS

2 stops11h 54mMultiple Airlines

Tue 12/92:59 pmCHS - STL

1 stop8h 34mMultiple Airlines

Deal found 11/8

$205

Mon 12/83:30 pmSTL - CHS

1 stop16h 07mMultiple Airlines

Thu 12/119:49 pmCHS - STL

2 stops12h 58mMultiple Airlines

Deal found 11/7

$216

Mon 12/87:43 pmSTL - CHS

2 stops11h 54mMultiple Airlines

Mon 12/153:33 pmCHS - STL

1 stop8h 00mMultiple Airlines

Deal found 11/8

$222

Thu 11/2010:53 amSTL - CHS

1 stop10h 12mMultiple Airlines

Mon 11/246:50 amCHS - STL

2 stops32h 39mMultiple Airlines

Deal found 11/5

$263

Tue 12/23:30 pmSTL - CHS

2 stops14h 56mMultiple Airlines

Thu 12/42:59 pmCHS - STL

1 stop8h 34mMultiple Airlines

Deal found 11/7

$266

Thu 12/113:30 pmSTL - CHS

1 stop16h 27mMultiple Airlines

Sat 12/1311:55 amCHS - STL

2 stops22h 52mMultiple Airlines

Deal found 11/6

$267

Tue 12/3010:48 amSTL - CHS

2 stops25h 22mMultiple Airlines

Tue 1/62:59 pmCHS - STL

1 stop8h 34mMultiple Airlines

Deal found 11/8

$274

Best flights from St. Louis to Charleston
Discover carefully curated flight deals from St. Louis to Charleston that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 8, 2025.

Mon 1/195:06 pmSTL - CHS

1 stop14h 32mMultiple Airlines

Fri 1/236:31 pmCHS - STL

2 stops29h 02mMultiple Airlines

Deal found 11/6

$200

Thu 1/1511:27 amSTL - CHS

1 stop8h 45mAmerican Airlines

Sun 1/1810:18 amCHS - STL

1 stop5h 46mAmerican Airlines

Deal found 11/7

$307

Tue 12/22:11 pmSTL - CHS

1 stop5h 23mDelta

Thu 12/412:51 pmCHS - STL

1 stop6h 05mDelta

Deal found 11/6

$328

Tue 12/212:45 pmSTL - CHS

1 stop4h 55mSouthwest

Thu 12/46:00 amCHS - STL

1 stop5h 50mSouthwest

Deal found 11/7

$335

Mon 12/89:54 amSTL - CHS

1 stop21h 43mMultiple Airlines

Tue 12/92:59 pmCHS - STL

1 stop8h 34mMultiple Airlines

Deal found 11/8

$208

Mon 12/83:30 pmSTL - CHS

1 stop16h 07mMultiple Airlines

Thu 12/119:49 pmCHS - STL

2 stops12h 58mMultiple Airlines

Deal found 11/7

$216

Mon 12/87:43 pmSTL - CHS

2 stops11h 54mMultiple Airlines

Mon 12/153:33 pmCHS - STL

1 stop8h 00mMultiple Airlines

Deal found 11/8

$222

Thu 12/117:02 pmSTL - CHS

1 stop3h 48mDelta

Sat 12/1311:31 amCHS - STL

1 stop6h 48mDelta

Deal found 11/6

$328

Thu 1/2210:42 amSTL - CHS

2 stops25h 40mMultiple Airlines

Sun 1/252:56 pmCHS - STL

1 stop17h 54mMultiple Airlines

Deal found 11/7

$253

Thu 11/2010:53 amSTL - CHS

1 stop10h 12mMultiple Airlines

Mon 11/246:50 amCHS - STL

2 stops32h 39mMultiple Airlines

Deal found 11/5

$263

Tue 12/23:30 pmSTL - CHS

2 stops30h 29mMultiple Airlines

Fri 12/53:33 pmCHS - STL

1 stop8h 00mMultiple Airlines

Deal found 11/6

$302

Sat 11/154:33 pmSTL - CHS

1 stop15h 04mMultiple Airlines

Tue 11/182:59 pmCHS - STL

1 stop20h 06mMultiple Airlines

Deal found 11/6

$309

Last-minute flights from St. Louis to Charleston
Discover last-minute flight deals from St. Louis to Charleston. Data last updated November 8, 2025 and is based on user searches.

Thu 11/2010:53 amSTL - CHS

1 stop10h 12mMultiple Airlines

Mon 11/246:50 amCHS - STL

2 stops32h 39mMultiple Airlines

Deal found 11/5

$263

Mon 12/14:13 pmSTL - CHS

1 stop15h 24mMultiple Airlines

Wed 12/36:15 pmCHS - STL

2 stops17h 52mMultiple Airlines

Deal found 11/7

$193

Tue 12/23:30 pmSTL - CHS

2 stops14h 56mMultiple Airlines

Thu 12/42:59 pmCHS - STL

1 stop8h 34mMultiple Airlines

Deal found 11/7

$266

Mon 12/87:43 pmSTL - CHS

2 stops11h 54mMultiple Airlines

Tue 12/92:59 pmCHS - STL

1 stop8h 34mMultiple Airlines

Deal found 11/8

$205

Mon 12/83:30 pmSTL - CHS

1 stop16h 07mMultiple Airlines

Thu 12/119:49 pmCHS - STL

2 stops12h 58mMultiple Airlines

Deal found 11/7

$216

Mon 12/87:43 pmSTL - CHS

2 stops11h 54mMultiple Airlines

Mon 12/153:33 pmCHS - STL

1 stop8h 00mMultiple Airlines

Deal found 11/8

$222

Thu 12/113:30 pmSTL - CHS

1 stop16h 27mMultiple Airlines

Sat 12/1311:55 amCHS - STL

2 stops22h 52mMultiple Airlines

Deal found 11/6

$267

Tue 12/3010:48 amSTL - CHS

2 stops25h 22mMultiple Airlines

Tue 1/62:59 pmCHS - STL

1 stop8h 34mMultiple Airlines

Deal found 11/8

$274

One-way flights from St. Louis to Charleston
Search for one-way flight options from St. Louis to Charleston. Find affordable one-way fares based on user searches. Data last updated November 8, 2025.

Mon 1/265:11 pmSTL - CHS

1 stop14h 27mMultiple Airlines

Deal found 11/6

$78

Mon 1/510:40 amSTL - CHS

1 stop20h 57mMultiple Airlines

Deal found 11/8

$79

Mon 1/195:06 pmSTL - CHS

1 stop14h 32mMultiple Airlines

Deal found 11/6

$83

Sat 1/245:11 pmSTL - CHS

1 stop14h 22mMultiple Airlines

Deal found 11/7

$89

Thu 1/85:11 pmSTL - CHS

1 stop14h 32mMultiple Airlines

Deal found 11/6

$90

Sun 1/255:11 pmSTL - CHS

1 stop14h 32mMultiple Airlines

Deal found 11/6

$100

Thu 12/1112:04 pmSTL - CHS

2 stops31h 50mMultiple Airlines

Deal found 11/6

$103

Thu 12/42:47 pmSTL - CHS

1 stop29h 07mSpirit Airlines

Deal found 11/6

$105

Mon 12/87:43 pmSTL - CHS

2 stops11h 54mMultiple Airlines

Deal found 11/6

$106

Mon 2/27:43 pmSTL - CHS

2 stops11h 55mMultiple Airlines

Deal found 11/6

$108

Cheapflights Fare Finder

Use the filters below to find and compare flights from St. Louis to Charleston that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Mon 1/19

5:06 pm-8:38 am

1 stop14h 32m

Charleston

Fri 1/23

6:31 pm-10:33 pm

2 stops29h 02m

$200

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Mon 12/8

9:54 am-8:37 am

1 stop21h 43m

Charleston

Tue 12/9

2:59 pm-10:33 pm

1 stop8h 34m

$208

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Mon 12/8

3:30 pm-8:37 am

1 stop16h 07m

Charleston

Thu 12/11

9:49 pm-9:47 am

2 stops12h 58m

$216

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Mon 12/8

7:43 pm-8:37 am

2 stops11h 54m

Charleston

Mon 12/15

3:33 pm-10:33 pm

1 stop8h 00m

$222

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Thu 1/22

10:42 am-1:22 pm

2 stops25h 40m

Charleston

Sun 1/25

2:56 pm-7:50 am

1 stop17h 54m

$253

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Thu 11/20

10:53 am-10:05 pm

1 stop10h 12m

Charleston

Mon 11/24

6:50 am-2:29 pm

2 stops32h 39m

$263

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Tue 12/2

3:30 pm-10:59 pm

2 stops30h 29m

Charleston

Fri 12/5

3:33 pm-10:33 pm

1 stop8h 00m

$302

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Thu 1/15

11:27 am-9:12 pm

1 stop8h 45m

Charleston

Sun 1/18

10:18 am-3:04 pm

1 stop5h 46m

$307

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Sat 11/15

4:33 pm-8:37 am

1 stop15h 04m

Charleston

Tue 11/18

2:59 pm-10:05 am

1 stop20h 06m

$309

St. LouisCharleston

STL - CHS

STLCHS

Lambert-St Louis

Tue 12/2

2:11 pm-8:34 pm

1 stop5h 23m

Charleston

Thu 12/4

12:51 pm-5:56 pm

1 stop6h 05m

$328

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/8

Showing 1-10 of 21 results

Compare providers for flights from St. Louis to Charleston

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Charleston in November.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars
Priceline	Price Accuracy1 star	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on St. Louis-Charleston flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on St. Louis-Charleston flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from St. Louis-Charleston flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on St. Louis-Charleston flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for St. Louis-Charleston flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from St. Louis to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from St. Louis with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Charleston

Prices

How far ahead should I book a flight from St. Louis to Charleston?

The price you pay for your flight from St. Louis to Charleston may vary depending on when you book. For the best chance of a lower fare, look to book 49 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from St. Louis to Charleston?

Currently, February is the cheapest month in which you can book a flight from St. Louis to Charleston (average of $84). Flying from St. Louis to Charleston in March is currently the most expensive (average of $306). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to CHS?

One of the essential ways to save on airfare from St. Louis to Charleston is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 15% on airfare.

What is the cheapest day to fly from St. Louis to Charleston?

Travelers seeking maximum savings on their St. Louis to Charleston flight should consider departing on Tuesday afternoons when fares are most often at their lowest. Monday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

The best insider tips for St. Louis to Charleston flights

Cheapflights partnered with top experts to bring you the best recommendations for your St. Louis to Charleston trip

Airports

STL

Expect security screening at STL to take 5-10 minutes during off-peak times. Check wait times online before heading to the airport.

CHS

For a quick ride to downtown Charleston, use rideshare services from CHS. They're convenient and offer in-app tracking.

Our travel experts

Taryn White

Expert on STL

Ramsey Qubein

Expert on CHS

Reviews of airlines servicing Charleston

Read through reviews of airlines operating flights from St. Louis to Charleston, such as Southwest, Delta, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,240 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Southwest

8.0

Very good

4,240 reviews

Southwest

8.0

Very good

4,240 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Delta

7.9

Good

8,002 reviews

Southwest

8.0

Very good

4,240 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

American Airlines

7.2

Good

11,050 reviews

Southwest

8.0

Very good

4,240 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

How popular is this St. Louis to Charleston flight route?
Flights from Lambert-St Louis to Charleston have been viewed 6 times in the past calendar month.
What are the cheapest airlines flying from St. Louis to Charleston round-trip?
Cheapflights users have booked flights from St. Louis to Charleston round-trip from $208. Other airlines that can offer you cheap pricing are American Airlines, from $275, and Southwest, from $286. These flights start at 46% lower than the current average price 3 months from now.
Can I find deals for flights from St. Louis to Charleston that include hotel bookings?
Yes. In addition to deals on St. Louis to Charleston flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from St. Louis to Charleston?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Charleston.
Can I find deals for business class flights from St. Louis to Charleston?
Yes. Cheapflights offers flight deals from St. Louis to Charleston by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from St. Louis to Charleston?
Currently, February is the cheapest month in which you can book a flight from St. Louis to Charleston (average of $84). Flying from St. Louis to Charleston in March is currently the most expensive (average of $306). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

North Charleston

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Walterboro

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Top 3 airlines flying from St. Louis to Charleston

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$208	Average$387	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$275	Average$375	FlexibilityNo cancel fee	On-time71%
Southwest	Cheapest$286	Average$405	FlexibilityNo cancel fee	On-time63%

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$78+ Cheap flights from St. Louis to Charleston (STL - CHS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/7. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from St. Louis to Charleston with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Lambert-St Louis to Charleston are usually found in August or October, booked 49 days in advance, depart on a Monday or Tuesday and return on a Thursday

Cheap flight deals from St. Louis to Charleston

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from St. Louis to Charleston

Cheapest flights from St. Louis to CharlestonExplore the most affordable flight options available from St. Louis to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 8, 2025.

Explore the most affordable flight options available from St. Louis to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 8, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from St. Louis to Charleston that are best for you.

Compare providers for flights from St. Louis to Charleston

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from St. Louis to Charleston in November.

Best time to book a flight from St. Louis to Charleston

Have a flexible travel schedule? Discover the best time to fly to Charleston from St. Louis with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Charleston

How far ahead should I book a flight from St. Louis to Charleston?

What is the cheapest month to book a flight from St. Louis to Charleston?

What is the cheapest time of day to fly from STL to CHS?

What is the cheapest day to fly from St. Louis to Charleston?

What’s the top layover airport for flights from St. Louis to Charleston?

What’s the fastest layover option from St. Louis to Charleston?

What’s the fastest layover option from St. Louis to Charleston?

Which airport typically offers the quickest layover for flights from St. Louis to Charleston?

The best insider tips for St. Louis to Charleston flights

Cheapflights partnered with top experts to bring you the best recommendations for your St. Louis to Charleston trip

Airports

STL

CHS

Our travel experts

Reviews of airlines servicing Charleston

Read through reviews of airlines operating flights from St. Louis to Charleston, such as Southwest, Delta, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Charleston. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How popular is this St. Louis to Charleston flight route?

What are the cheapest airlines flying from St. Louis to Charleston round-trip?

Can I find deals for flights from St. Louis to Charleston that include hotel bookings?

How can I find direct flights from St. Louis to Charleston?

Can I find deals for business class flights from St. Louis to Charleston?

What is the cheapest month to book a flight from St. Louis to Charleston?

Traveling to a place near Charleston?

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Alternative routes for St. Louis to Charleston

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from St. Louis to Charleston

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Cheapest flights from St. Louis to Charleston
Explore the most affordable flight options available from St. Louis to Charleston. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 8, 2025.