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$145+ Cheap flights from Panama City (PTY) to Cali (CLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/28. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CLO
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheapflights Tip: The best prices from Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl are usually found in April or May, booked 73 days in advance, depart on a Monday or Tuesday and return on a Thursday

Cheap flight deals from Panama City to Cali

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Cali (CLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$267
(Copa Airlines)

One-way from

$145
(Copa Airlines)

Popular in

July

Cheapest in

April

Average price

$221

Good round-trip deal

$146 or less

Good one-way deal

$166 or less
From Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl
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One-way flight from Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl
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Highest demand for flights based on searches. 8% potential increase in price ($21 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($4 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl.
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Price to beat on a one-way flight from Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl.
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Find flight deals from Panama City to Cali

Cheapest flights from Panama City to Cali
Explore the most affordable flight options available from Panama City to Cali. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Copa Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/129:21 amPTY - CLO
Nonstop1h 37mCopa Airlines
Wed 9/178:48 amCLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 9/11$267
This Priceline deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/213:20 amPTY - CLO
1 stop4h 58mAvianca
Tue 10/288:55 pmCLO - PTY
1 stop4h 05mAvianca
Deal found 9/9$273
This Avianca deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1211:00 amPTY - CLO
1 stop5h 16mAvianca
Sun 9/215:41 amCLO - PTY
1 stop4h 29mAvianca
Deal found 9/11$283
This Copa Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:29 pmPTY - CLO
Nonstop1h 42mCopa Airlines
Wed 12/173:11 pmCLO - PTY
Nonstop1h 33mCopa Airlines
Deal found 9/11$288
This Avianca deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/32:55 amPTY - CLO
1 stop4h 15mAvianca
Thu 12/1112:40 pmCLO - PTY
1 stop4h 15mAvianca
Deal found 9/10$293
This Copa Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/19:20 amPTY - CLO
Nonstop1h 41mCopa Airlines
Mon 11/174:52 amCLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 9/11$299
This Copa Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/129:21 amPTY - CLO
Nonstop1h 37mCopa Airlines
Mon 9/153:23 pmCLO - PTY
Nonstop1h 31mCopa Airlines
Deal found 9/11$301
This Trip.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1912:43 pmPTY - CLO
Nonstop1h 42mMultiple Airlines
Thu 10/237:24 pmCLO - PTY
1 stop4h 46mMultiple Airlines
Deal found 9/11$306
This Gotogate deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/222:55 amPTY - CLO
1 stop4h 15mAvianca
Fri 1/28:15 pmCLO - PTY
1 stop4h 25mAvianca
Deal found 9/11$308
This Avianca deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/269:45 amPTY - CLO
1 stop5h 00mAvianca
Fri 12/268:15 pmCLO - PTY
1 stop4h 25mAvianca
Deal found 9/9$313
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/253:20 amPTY - CLO
1 stop4h 15mMultiple Airlines
Mon 9/2912:01 pmCLO - PTY
Nonstop1h 31mMultiple Airlines
Deal found 9/11$316
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/213:20 amPTY - CLO
1 stop7h 23mMultiple Airlines
Tue 10/283:12 pmCLO - PTY
Nonstop1h 32mMultiple Airlines
Deal found 9/9$317

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Cali that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Panama City to Cali that are best for you.

Fly from

Panama City

Fly to

Cali

Route

Depart

Return

Price

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 10/24

12:43 pm-2:25 pm

Nonstop1h 42m

Cali Alfonso B. Aragon Intl

Sat 11/8

3:12 pm-4:44 pm

Nonstop1h 32m

$267

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Wed 10/22

3:47 pm-5:29 pm

Nonstop1h 42m

Cali Alfonso B. Aragon Intl

Sun 10/26

8:48 am-10:20 am

Nonstop1h 32m

$267

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Mon 11/10

3:47 pm-5:29 pm

Nonstop1h 42m

Cali Alfonso B. Aragon Intl

Fri 11/28

12:04 pm-1:36 pm

Nonstop1h 32m

$267

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Sun 11/2

9:20 am-11:01 am

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Wed 11/5

8:48 am-10:20 am

Nonstop1h 32m

$267

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Wed 9/24

3:47 pm-5:25 pm

Nonstop1h 38m

Cali Alfonso B. Aragon Intl

Mon 9/29

12:01 pm-1:32 pm

Nonstop1h 31m

$267

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Mon 9/22

12:43 pm-2:21 pm

Nonstop1h 38m

Cali Alfonso B. Aragon Intl

Thu 9/25

12:01 pm-1:32 pm

Nonstop1h 31m

$267

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 11/7

9:20 am-11:01 am

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

Mon 11/10

8:48 am-10:20 am

Nonstop1h 32m

$267

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Thu 9/25

12:43 pm-2:21 pm

Nonstop1h 38m

Cali Alfonso B. Aragon Intl

Mon 9/29

12:01 pm-1:32 pm

Nonstop1h 31m

$267

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 9/26

12:43 pm-2:21 pm

Nonstop1h 38m

Cali Alfonso B. Aragon Intl

Sun 9/28

8:48 am-10:20 am

Nonstop1h 32m

$267

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Wed 10/8

12:43 pm-2:25 pm

Nonstop1h 42m

Cali Alfonso B. Aragon Intl

Mon 10/13

8:47 am-10:20 am

Nonstop1h 33m

$267

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Showing 1-10 of 20 results
1
2

Best time to book a flight from Panama City to Cali

Have a flexible travel schedule? Discover the best time to fly to Cali from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Cali

How far ahead should I book a flight from Panama City to Cali?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to Cali. Price data was last updated on August 29, 2025.

The best time to book flights from Panama City to Cali is 73 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Panama City to Cali?

Currently, January is the cheapest month in which you can book a flight from Panama City to Cali (average of $351). Flying from Panama City to Cali in December is currently the most expensive (average of $669). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to CLO?

Find hourly flight availability from Panama City to Cali. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

A simple way to save on the total cost of your ticket is to fly from Panama City to Cali in the morning. If you’re flexible enough to do this you can expect to save up to 17% on your trip compared to booking a flight in the afternoon.

How much does it cost to fly round-trip from Panama City to Cali?

Reviews of airlines servicing Cali

Get insights into the airlines that provide service to Cali. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cali. Reviews last updated September 11, 2025.
Read through reviews of airlines operating flights from Panama City to Cali, such as Copa Airlines and Avianca. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,531 reviews

Boarding

7.8

Crew

8.1

Entertainment

6.8

Overall

7.6

Comfort

7.4

Food

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,531 reviews
Copa Airlines
7.6
Good
1,531 reviews

Boarding

7.8

Crew

8.1

Entertainment

6.8

Overall

7.6

Comfort

7.4

Food

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Avianca
6.7
Okay
2,436 reviews
Copa Airlines
7.6
Good
1,531 reviews

Boarding

7.8

Crew

8.1

Entertainment

6.8

Overall

7.6

Comfort

7.4

Food

6.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from Panama City to Cali. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Panama City to Cali?

    You will need to book a flight from Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl if you want to fly from Panama City to Cali. At least 3 different airlines have flights from Tocumen Intl (PTY) to Alfonso B. Aragon Intl (CLO) on a regular basis. There are 8 flights to Cali from the Panama City airport per day. If you manage to book one that is nonstop, then you can expect the flight time from PTY to CLO to be around 1h 34m.

  • How popular is this Panama City to Cali flight route?

    This flight path from Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Panama City to Cali?

    Departing from Panama City to Cali will take you 1h 42m. The distance from Panama City to Cali is about 434 mi. Most flights are nonstop.

  • What are the cheapest airlines flying from Panama City to Cali round-trip?

    Flying on Wingo is currently your cheapest option to Cali, with prices starting at $71. Additional round-trip tickets that might be worth considering are offered by Copa Airlines and Avianca, with the lowest prices starting at $112 and $206, respectively. You may be able to fly from Panama City to Cali for 67% less than the average price by searching for these airlines.

  • What are the most reliable airlines from Panama City to Cali?

    No one likes to see their flight delayed. When booking a flight from Panama City to Cali consider choosing Copa Airlines (92%), KLM (88%) or Turkish Airlines (88%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Panama City to Cali?

    Looking at all options, your cheapest flight can be booked for $115. While the most popular route (Panama City Tocumen Intl - Cali Alfonso B. Aragon Intl) can be booked for $138 on average, our data indicates $216 when flying from Panama City to Cali.

  • Can I find deals for flights from Panama City to Cali that include hotel bookings?

    Yes. In addition to deals on Panama City to Cali flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Cali?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Cali.

  • Can I find deals for business class flights from Panama City to Cali?

    Yes. Cheapflights offers flight deals from Panama City to Cali by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Cali?

    Currently, January is the cheapest month in which you can book a flight from Panama City to Cali (average of $351). Flying from Panama City to Cali in December is currently the most expensive (average of $669). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Panama City to Cali

Discover the top 3 airlines that operate flights from Panama City to Cali. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
WingoCheapest$71Average$155FlexibilityNo cancel feeOn-time83%
Copa AirlinesCheapest$112Average$266FlexibilityNo cancel feeOn-time70%
AviancaCheapest$206Average$254FlexibilityNo cancel feeOn-time71%

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