How popular is this Panama City to Cali flight route?

This flight path from Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

What are the cheapest airlines flying from Panama City to Cali round-trip?

Flying on Avianca is currently your cheapest option to Cali, with prices starting at $260. Another option worth looking into is Copa Airlines, starting at $261 round trip.

What is the cheapest day to fly from Panama City to Cali?

Travelers seeking maximum savings on their Panama City to Cali flight should consider departing on Sunday evenings when fares are most often at their lowest. Saturday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Cali ranges from 1.2 - 5.5 inches per month. April is typically the wettest month, when rainfall can reach 5.5 in. July is typically the driest time to visit Cali when rainfall is around 1.2 in.

If weather is an important factor for your trip to Cali, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

What are the cheapest flights from Panama City to Cali?

Looking at all options, your cheapest flight can be booked for $176. While the most popular route (Panama City Tocumen Intl - Cali Alfonso B. Aragon Intl) can be booked for $227 on average our data indicates $248 when flying from Panama City to Cali.

What are the most reliable airlines from Panama City to Cali?

No one likes to see their flight delayed. When booking a flight from Panama City to Cali consider choosing Copa Airlines (87%), KLM (87%) or Turkish Airlines (87%) as they are the most reliable in getting you off to your destination on time.

What are the most popular airlines that fly from Panama City to Cali?

Consider Avianca, Copa Airlines or Wingo when booking your flight. These represent the most popular airlines when flying from Panama City to Cali.

What is the cheapest day to fly round-trip from Panama City to Cali?

Departing on a Sunday is a good option for securing a great price. You can expect to save up to 119% when planning your travel around this day of the week.

How far in advance should I book a flight from Panama City to Cali?

Find a great deal and save up to 39% by booking at least 34 days prior to your desired departure date, rather than waiting until the week of travel. According to our data, there are a number of flights available from Panama City to Cali within the next two weeks, with the cheapest ticket starting at $190.

What is the cheapest month to fly from Panama City to Cali?

Flights from Panama City to Cali lean towards being more expensive in July. Prices are generally better when you fly from Panama City to Cali in April, with the cheapest ticket starting at $71.

What airports do I use to fly from Panama City to Cali?

You will need to book a flight from Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl if you want to fly from Panama City to Cali. At least 3 different airlines have flights from Tocumen Intl (PTY) to Alfonso B. Aragon Intl (CLO) on a regular basis. There are 4 flights to Cali from the Panama City airport per day. If you manage to book one that is nonstop, then you can expect the flight time from PTY to CLO to be around 1h 34m.

Can I find deals for flights from Panama City to Cali that include hotel bookings?

Yes. In addition to deals on Panama City to Cali flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Panama City to Cali?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Cali.

Can I find deals for business class flights from Panama City to Cali?

Yes. Cheapflights offers flight deals from Panama City to Cali by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$147+ Flights from Panama City to Cali

Q: How much does it cost to fly round-trip from Panama City to Cali?

Airfare is typical for this route at the moment. Panama City to Cali flights typically cost between $142 and $262 in August. The cheapest round-trip price found within the last 3 days was $260 on Avianca (Aug 14-Aug 18).

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

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Cheapflights Tip: The best prices from Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl are usually found in April or May, booked 73 days in advance, depart on a Monday or Friday and return on a Thursday

Cheap flight deals from Panama City to Cali

Round-trip from	$260 (Mytrip)
One-way from	$147 (Priceline)
Popular in	July
Cheapest in	April
Average price	$267
Good round-trip deal	$71 or less
Good one-way deal	$208 or less

From Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl

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One-way flight from Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl

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Highest demand for flights based on searches. 8% potential increase in price ($19 potential increase over avg. RT price).

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Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).

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Average for round-trip flights in July 2025

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Price to beat on a round-trip flight from Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl.

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Price to beat on a one-way flight from Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl.

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Find flight deals from Panama City to Cali

Cheapest flights from Panama City to Cali
Explore the most affordable flight options available from Panama City to Cali. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.

Thu 8/143:20 amPTY - CLO

1 stop5h 51mAvianca

Mon 8/186:18 pmCLO - PTY

1 stop6h 27mAvianca

Deal found 7/29

$260

Fri 8/2212:43 pmPTY - CLO

Nonstop1h 38mCopa Airlines

Tue 9/98:48 amCLO - PTY

Nonstop1h 32mCopa Airlines

Deal found 7/28

$261

Wed 8/2012:43 pmPTY - CLO

Nonstop1h 38mMultiple Airlines

Sun 8/2410:24 amCLO - PTY

1 stop6h 06mMultiple Airlines

Deal found 7/29

$328

Best flights from Panama City to Cali
Discover carefully curated flight deals from Panama City to Cali that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 30, 2025.

Thu 8/143:20 amPTY - CLO

1 stop5h 51mAvianca

Mon 8/186:18 pmCLO - PTY

1 stop6h 27mAvianca

Deal found 7/29

$260

Fri 8/2212:43 pmPTY - CLO

Nonstop1h 38mCopa Airlines

Mon 9/88:48 amCLO - PTY

Nonstop1h 32mCopa Airlines

Deal found 7/28

$261

Wed 8/2012:43 pmPTY - CLO

Nonstop1h 38mMultiple Airlines

Sun 8/2410:24 amCLO - PTY

1 stop6h 06mMultiple Airlines

Deal found 7/29

$328

Last-minute flights from Panama City to Cali
Discover last-minute flight deals from Panama City to Cali. Data last updated July 30, 2025 and is based on user searches.

Tue 8/53:20 amPTY - CLO

1 stop4h 58mAvianca

Tue 8/266:50 pmCLO - PTY

1 stop5h 20mAvianca

Deal found 7/30

$266

Tue 8/53:20 amPTY - CLO

1 stop4h 15mMultiple Airlines

Tue 8/268:48 amCLO - PTY

Nonstop1h 32mMultiple Airlines

Deal found 7/30

$333

Fri 8/89:20 amPTY - CLO

Nonstop1h 38mCopa Airlines

Wed 8/136:17 pmCLO - PTY

Nonstop1h 32mCopa Airlines

Deal found 7/28

$261

Thu 8/143:20 amPTY - CLO

1 stop5h 51mAvianca

Mon 8/186:18 pmCLO - PTY

1 stop6h 27mAvianca

Deal found 7/29

$260

Wed 8/2012:43 pmPTY - CLO

Nonstop1h 38mMultiple Airlines

Sun 8/2410:24 amCLO - PTY

1 stop6h 06mMultiple Airlines

Deal found 7/29

$328

Fri 8/2212:43 pmPTY - CLO

Nonstop1h 38mCopa Airlines

Mon 9/88:48 amCLO - PTY

Nonstop1h 32mCopa Airlines

Deal found 7/28

$261

One-way flights from Panama City to Cali
Search for one-way flight options from Panama City to Cali. Find affordable one-way fares based on user searches. Data last updated July 30, 2025.

Mon 8/411:00 amPTY - CLO

1 stop7h 36mAvianca

Deal found 7/29

$147

Mon 8/259:21 amPTY - CLO

Nonstop1h 37mCopa Airlines

Deal found 7/28

$166

Mon 8/411:20 amPTY - CLO

2 stops26h 28mMultiple Airlines

Deal found 7/28

$206

Fly from

Fly to

Route

Depart

Return

Price

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Thu 8/14

3:20 am-9:11 am

1 stop5h 51m

Cali Alfonso B. Aragon Intl

Mon 8/18

6:18 pm-12:45 am

1 stop6h 27m

$260

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Fri 8/22

12:43 pm-2:21 pm

Nonstop1h 38m

Cali Alfonso B. Aragon Intl

Mon 9/8

8:48 am-10:20 am

Nonstop1h 32m

$261

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Wed 8/20

12:43 pm-2:21 pm

Nonstop1h 38m

Cali Alfonso B. Aragon Intl

Sun 8/24

10:24 am-4:30 pm

1 stop6h 06m

$328

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Mon 8/4

11:00 am-6:36 pm

1 stop7h 36m

$147

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Mon 8/25

9:21 am-10:58 am

Nonstop1h 37m

$166

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

Mon 8/4

11:20 am-1:48 pm

2 stops26h 28m

$206

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Best time to book a flight from Panama City to Cali

Have a flexible travel schedule? Discover the best time to fly to Cali from Panama City with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Cali

How far ahead should I book a flight from Panama City to Cali?

The best time to book flights from Panama City to Cali is 73 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Panama City to Cali?

Currently, January is the cheapest month in which you can book a flight from Panama City to Cali (average of $351). Flying from Panama City to Cali in December is currently the most expensive (average of $669). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to CLO?

A simple way to save on the total cost of your ticket is to fly from Panama City to Cali in the morning. If you’re flexible enough to do this you can expect to save up to 16% on your trip compared to booking a flight in the afternoon.

How much does it cost to fly round-trip from Panama City to Cali?

Reviews of airlines servicing Cali

Read through reviews of airlines operating flights from Panama City to Cali, such as Copa Airlines and Avianca. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Copa Airlines

7.5

Good

1,493 reviews

Reviews

1 / 20

4.0

Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.

Copa Airlines

7.5

Good

1,493 reviews

Copa Airlines

7.5

Good

1,493 reviews

Reviews

1 / 20

4.0

Okay

Paul,Jun 2025

PTY - MIA

Avianca

6.7

Okay

2,387 reviews

Copa Airlines

7.5

Good

1,493 reviews

Reviews

1 / 20

4.0

Okay

Paul,Jun 2025

PTY - MIA

Related info for your journey

What airports do I use to fly from Panama City to Cali?
You will need to book a flight from Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl if you want to fly from Panama City to Cali. At least 3 different airlines have flights from Tocumen Intl (PTY) to Alfonso B. Aragon Intl (CLO) on a regular basis. There are 4 flights to Cali from the Panama City airport per day. If you manage to book one that is nonstop, then you can expect the flight time from PTY to CLO to be around 1h 34m.
How popular is this Panama City to Cali flight route?
This flight path from Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.
What are the cheapest airlines flying from Panama City to Cali round-trip?
Flying on Avianca is currently your cheapest option to Cali, with prices starting at $260. Another option worth looking into is Copa Airlines, starting at $261 round trip.
What are the most reliable airlines from Panama City to Cali?
No one likes to see their flight delayed. When booking a flight from Panama City to Cali consider choosing Copa Airlines (87%), KLM (87%) or Turkish Airlines (87%) as they are the most reliable in getting you off to your destination on time.
What are the cheapest flights from Panama City to Cali?
Looking at all options, your cheapest flight can be booked for $176. While the most popular route (Panama City Tocumen Intl - Cali Alfonso B. Aragon Intl) can be booked for $227 on average our data indicates $248 when flying from Panama City to Cali.
Can I find deals for flights from Panama City to Cali that include hotel bookings?
Yes. In addition to deals on Panama City to Cali flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Panama City to Cali?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Cali.
Can I find deals for business class flights from Panama City to Cali?
Yes. Cheapflights offers flight deals from Panama City to Cali by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Panama City to Cali?
Currently, January is the cheapest month in which you can book a flight from Panama City to Cali (average of $351). Flying from Panama City to Cali in December is currently the most expensive (average of $669). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama City to Cali

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Other flights to Cali

Top 3 airlines flying from Panama City to Cali

Airline	Cheapest	Average	Flexibility	On-time
Wingo	Cheapest$70	Average$155	FlexibilityNo cancel fee	On-time83%
Copa Airlines	Cheapest$112	Average$266	FlexibilityNo cancel fee	On-time70%
Avianca	Cheapest$204	Average$232	FlexibilityNo cancel fee	On-time71%

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$147+ Cheap flights from Panama City (PTY) to Cali (CLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/4. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Panama City to Cali with Cheapflights

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2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl are usually found in April or May, booked 73 days in advance, depart on a Monday or Friday and return on a Thursday

Cheap flight deals from Panama City to Cali

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One-way from

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Good one-way deal

Find flight deals from Panama City to Cali

Cheapest flights from Panama City to CaliExplore the most affordable flight options available from Panama City to Cali. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.

Explore the most affordable flight options available from Panama City to Cali. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Panama City to Cali that are best for you.

Best time to book a flight from Panama City to Cali

Have a flexible travel schedule? Discover the best time to fly to Cali from Panama City with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Cali

How far ahead should I book a flight from Panama City to Cali?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to Cali. Price data was last updated on July 25, 2025.

What is the cheapest month to book a flight from Panama City to Cali?

What is the cheapest time of day to fly from PTY to CLO?

Find hourly flight availability from Panama City to Cali. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 30, 2025.

How much does it cost to fly round-trip from Panama City to Cali?

Reviews of airlines servicing Cali

Get insights into the airlines that provide service to Cali. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cali. Reviews last updated July 30, 2025.

Read through reviews of airlines operating flights from Panama City to Cali, such as Copa Airlines and Avianca. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Cali. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airports do I use to fly from Panama City to Cali?

How popular is this Panama City to Cali flight route?

What are the cheapest airlines flying from Panama City to Cali round-trip?

What are the most reliable airlines from Panama City to Cali?

What are the cheapest flights from Panama City to Cali?

Can I find deals for flights from Panama City to Cali that include hotel bookings?

How can I find direct flights from Panama City to Cali?

Can I find deals for business class flights from Panama City to Cali?

What is the cheapest month to book a flight from Panama City to Cali?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Panama City to Cali

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Panama City to Cali

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Cheapest flights from Panama City to Cali
Explore the most affordable flight options available from Panama City to Cali. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.