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$161+ Cheap flights from Panama City (PTY) to Cali (CLO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/22. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — CLO
ene. 11 — ene. 181
dom. 1/11
dom. 1/18
1 adult, Economy
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Cheapflights Tip: The best prices from Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl are usually found in May or February, booked 33 days in advance, depart on a Saturday or Wednesday and return on a Thursday

Cheap flight deals from Panama City to Cali

Cheapest flights from Panama City to Cali
Explore the most affordable flight options available from Panama City to Cali. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 12, 2025.

This Copa Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/309:20 amPTY - CLO
Nonstop1h 41mCopa Airlines
jue. 1/158:48 amCLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 12/10$299
This Mytrip deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/242:55 pmPTY - CLO
1 stop5h 20mAvianca
dom. 12/2811:55 amCLO - PTY
1 stop5h 00mAvianca
Deal found 12/10$303
This Avianca deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/262:55 pmPTY - CLO
1 stop5h 00mAvianca
dom. 12/288:40 pmCLO - PTY
1 stop4h 20mAvianca
Deal found 12/11$305
This Copa Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/2912:29 pmPTY - CLO
Nonstop1h 42mCopa Airlines
jue. 1/158:48 amCLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 12/10$310
This Priceline deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/199:45 amPTY - CLO
1 stop5h 00mAvianca
lun. 12/2211:50 amCLO - PTY
1 stop5h 05mAvianca
Deal found 12/9$323
This Copa Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 12/213:55 pmPTY - CLO
Nonstop1h 42mCopa Airlines
dom. 1/2512:03 pmCLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 12/10$329
This Priceline deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/229:45 amPTY - CLO
1 stop5h 00mAvianca
jue. 1/112:40 pmCLO - PTY
1 stop4h 15mAvianca
Deal found 12/10$334
This Priceline deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/242:55 pmPTY - CLO
1 stop5h 00mAvianca
vie. 1/28:15 pmCLO - PTY
1 stop4h 25mAvianca
Deal found 12/9$336
This Copa Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/2312:29 pmPTY - CLO
Nonstop1h 42mCopa Airlines
lun. 12/293:11 pmCLO - PTY
Nonstop1h 33mCopa Airlines
Deal found 12/10$340
This Copa Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/183:47 pmPTY - CLO
Nonstop1h 42mCopa Airlines
lun. 12/2212:04 pmCLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 12/9$342
This Copa Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/153:47 pmPTY - CLO
Nonstop1h 42mCopa Airlines
lun. 1/2612:03 pmCLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 12/9$352
This Copa Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/3112:29 pmPTY - CLO
Nonstop1h 42mCopa Airlines
mié. 1/712:03 pmCLO - PTY
Nonstop1h 32mCopa Airlines
Deal found 12/10$358

Find flight deals from Panama City to Cali

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Cali (CLO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated diciembre 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$299
(Copa Airlines)

One-way from

$161
(Copa Airlines)

Popular in

December

Cheapest in

May

Average price

$283

Good round-trip deal

$164 or less

Good one-way deal

$160 or less
Provider with most accurate pricing for Panama City Tocumen Intl-Cali Alfonso B. Aragon Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City Tocumen Intl-Cali Alfonso B. Aragon Intl flights.
Search Deals
From Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl
Search Deals
One-way flight from Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($16 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($4 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl.
Search Deals
Price to beat on a one-way flight from Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Cali that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 12, 2025.
Use the filters below to find and compare flights from Panama City to Cali that are best for you.

Fly from

Panama City

Fly to

Cali

Route

Depart

Return

Price

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

vie. 2/13

4:00 pm-5:50 pm

Nonstop1h 50m

Cali Alfonso B. Aragon Intl

lun. 2/16

12:03 pm-1:35 pm

Nonstop1h 32m

$299

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

jue. 2/19

12:29 pm-2:10 pm

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

mié. 2/25

12:03 pm-1:35 pm

Nonstop1h 32m

$299

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

mié. 12/31

9:55 pm-11:37 pm

Nonstop1h 42m

Cali Alfonso B. Aragon Intl

lun. 1/26

12:03 pm-1:35 pm

Nonstop1h 32m

$299

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

jue. 1/8

9:20 am-11:00 am

Nonstop1h 40m

Cali Alfonso B. Aragon Intl

sáb. 1/24

12:03 pm-1:35 pm

Nonstop1h 32m

$299

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

vie. 2/13

4:00 pm-5:50 pm

Nonstop1h 50m

Cali Alfonso B. Aragon Intl

vie. 2/20

5:03 am-6:34 am

Nonstop1h 31m

$299

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

jue. 1/8

9:20 am-11:00 am

Nonstop1h 40m

Cali Alfonso B. Aragon Intl

jue. 1/15

8:48 am-10:20 am

Nonstop1h 32m

$299

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

mié. 12/31

9:55 pm-11:37 pm

Nonstop1h 42m

Cali Alfonso B. Aragon Intl

jue. 1/15

8:48 am-10:20 am

Nonstop1h 32m

$299

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

vie. 5/1

12:29 pm-2:10 pm

Nonstop1h 41m

Cali Alfonso B. Aragon Intl

dom. 5/3

5:00 am-6:34 am

Nonstop1h 34m

$299

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

lun. 12/22

3:55 pm-5:37 pm

Nonstop1h 42m

Cali Alfonso B. Aragon Intl

lun. 3/2

5:03 am-6:34 am

Nonstop1h 31m

$299

Panama CityCali

PTY - CLO

PTYCLO

Panama City Tocumen Intl

mié. 1/14

9:20 am-11:00 am

Nonstop1h 40m

Cali Alfonso B. Aragon Intl

dom. 1/18

8:48 am-10:20 am

Nonstop1h 32m

$299

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 18 results
1
2

Compare providers for flights from Panama City to Cali

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to Cali in December.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Panama City-Cali flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Panama City-Cali flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Panama City-Cali flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Panama City-Cali flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City-Cali flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to Cali

Have a flexible travel schedule? Discover the best time to fly to Cali from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Cali

How far ahead should I book a flight from Panama City to Cali?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to Cali. Price data was last updated on December 5, 2025.

The best time to book flights from Panama City to Cali is 33 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Panama City to Cali?

Currently, April is the cheapest month in which you can book a flight from Panama City to Cali (average of $70). Flying from Panama City to Cali in July is currently the most expensive (average of $122). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to CLO?

Find hourly flight availability from Panama City to Cali. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated diciembre 12, 2025.

A simple way to save on the total cost of your ticket is to fly from Panama City to Cali at noon. If you’re flexible enough to do this you can expect to save up to 59% on your trip compared to booking a flight in the evening.

How much does it cost to fly round-trip from Panama City to Cali?

Reviews of airlines servicing Cali

Get insights into the airlines that provide service to Cali. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cali. Reviews last updated diciembre 12, 2025.
Read through reviews of airlines operating flights from Panama City to Cali, such as Copa Airlines and Avianca. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,558 reviews

Overall

7.6

Boarding

7.8

Comfort

7.4

Entertainment

6.8

Food

6.9

Crew

8.1

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,558 reviews
Copa Airlines
7.6
Good
1,558 reviews

Overall

7.6

Boarding

7.8

Comfort

7.4

Entertainment

6.8

Food

6.9

Crew

8.1

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Avianca
6.6
Okay
2,479 reviews
Copa Airlines
7.6
Good
1,558 reviews

Overall

7.6

Boarding

7.8

Comfort

7.4

Entertainment

6.8

Food

6.9

Crew

8.1

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from Panama City to Cali. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Panama City to Cali?

    You will need to book a flight from Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl if you want to fly from Panama City to Cali. At least 3 different airlines have flights from Tocumen Intl (PTY) to Alfonso B. Aragon Intl (CLO) on a regular basis. There are 7 flights to Cali from the Panama City airport per day. If you manage to book one that is nonstop, then you can expect the flight time from PTY to CLO to be around 1h 29m.

  • How popular is this Panama City to Cali flight route?

    This flight path from Panama City Tocumen Intl to Cali Alfonso B. Aragon Intl was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Panama City to Cali?

    Departing from Panama City to Cali will take you 1h 50m. The distance from Panama City to Cali is about 434 mi. Most flights are nonstop.

  • What are the cheapest airlines flying from Panama City to Cali round-trip?

    Flying on Wingo is currently your cheapest option to Cali, with prices starting at $71. Additional round-trip tickets that might be worth considering are offered by Copa Airlines and Avianca, with the lowest prices starting at $112 and $170, respectively. You may be able to fly from Panama City to Cali for 70% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Panama City to Cali one-way?

    For one-way options, check prices for Wingo. According to our data, you can fly for as low as $66. Users have also found prices from $119 and $123 on Avianca and Copa Airlines, respectively.

  • What are the most reliable airlines from Panama City to Cali?

    No one likes to see their flight delayed. When booking a flight from Panama City to Cali consider choosing KLM (98%), Turkish Airlines (98%) or Copa Airlines (95%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Panama City to Cali?

    Looking at all options, your cheapest flight can be booked for $103. While the most popular route (Panama City Tocumen Intl - Cali Alfonso B. Aragon Intl) can be booked for $299 on average, our data indicates $244 when flying from Panama City to Cali.

  • Can I find deals for flights from Panama City to Cali that include hotel bookings?

    Yes. In addition to deals on Panama City to Cali flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Cali?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Cali.

  • Can I find deals for business class flights from Panama City to Cali?

    Yes. Cheapflights offers flight deals from Panama City to Cali by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Cali?

    Currently, April is the cheapest month in which you can book a flight from Panama City to Cali (average of $70). Flying from Panama City to Cali in July is currently the most expensive (average of $122). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Panama City to Cali

Discover the top 3 airlines that operate flights from Panama City to Cali. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
WingoCheapest$73Average$164FlexibilityNo cancel feeOn-time83%
Copa AirlinesCheapest$122Average$266FlexibilityNo cancel feeOn-time70%
AviancaCheapest$211Average$264FlexibilityNo cancel feeOn-time71%

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