HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Buffalo

$61+ Cheap flights from South Carolina to Buffalo (BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/19. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — BUF
Nov 30 — Dec 71
Sun 11/30
Sun 12/7
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from South Carolina to Buffalo with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from South Carolina to Buffalo

Keep the following information in mind while searching for South Carolina to Buffalo flight deals. Data was last updated October 31, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$167
(Kiwi.com)

One-way from

$61
(CheapOair)

Popular in

May

Cheapest in

September

Average price

$354
Provider with most accurate pricing for Myrtle Beach Intl-Buffalo flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Buffalo flights.
Search Deals
From South Carolina to Buffalo
Search Deals
One-way flight from South Carolina to Buffalo
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($49 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Find flight deals from South Carolina to Buffalo

Cheapest flights from South Carolina to Buffalo
Explore the most affordable flight options available from South Carolina to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 31, 2025.

This CheapOair deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/712:18 pmCLT - BUF
1 stop21h 50mFrontier
Thu 11/138:54 pmBUF - CLT
1 stop14h 34mFrontier
Deal found 10/29$143
This CheapOair deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/142:55 pmCLT - BUF
1 stop27h 22mFrontier
Mon 11/179:53 pmBUF - CLT
1 stop15h 39mFrontier
Deal found 10/29$163
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/510:33 pmCLT - BUF
1 stop15h 42mFrontier
Sun 12/143:18 pmBUF - CLT
1 stop18h 19mFrontier
Deal found 10/30$167
This CheapOair deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/712:18 pmCLT - BUF
1 stop21h 50mFrontier
Sun 11/98:54 pmBUF - CLT
1 stop11h 11mFrontier
Deal found 10/29$176
This CheapOair deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/69:57 amCLT - BUF
1 stop25h 47mFrontier
Thu 11/138:54 pmBUF - CLT
1 stop14h 34mFrontier
Deal found 10/30$180
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/197:54 pmCLT - BUF
1 stop14h 51mFrontier
Mon 11/2411:57 amBUF - CLT
1 stop20h 19mFrontier
Deal found 10/29$183
This JetBlue deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/196:15 amCHS - BUF
1 stop5h 04mJetBlue
Mon 11/2412:35 pmBUF - CHS
1 stop4h 40mJetBlue
Deal found 10/30$185
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/192:05 pmCLT - BUF
1 stop20h 40mMultiple Airlines
Sun 11/2312:20 pmBUF - CLT
1 stop28h 53mMultiple Airlines
Deal found 10/30$188
This CheapOair deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1110:33 pmCLT - BUF
1 stop13h 18mFrontier
Mon 12/153:18 pmBUF - CLT
1 stop18h 32mFrontier
Deal found 10/29$189
This CheapOair deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/197:54 pmCLT - BUF
1 stop14h 51mFrontier
Sat 11/2211:47 amBUF - CLT
1 stop20h 12mFrontier
Deal found 10/29$190
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/139:34 amCLT - BUF
2 stops10h 35mMultiple Airlines
Sun 11/166:59 pmBUF - CLT
1 stop14h 03mMultiple Airlines
Deal found 10/30$193
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/128:04 pmCLT - BUF
2 stops17h 33mFrontier
Sun 11/166:59 pmBUF - CLT
1 stop14h 03mFrontier
Deal found 10/29$194

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 31, 2025.
Use the filters below to find and compare flights from South Carolina to Buffalo that are best for you.

Fly from

South Carolina

Fly to

Buffalo

Route

Depart

Return

Price

CharlestonBuffalo

CHS - BUF

CHSBUF

Charleston

Wed 11/19

6:15 am-11:19 am

1 stop5h 04m

Buffalo

Mon 11/24

12:35 pm-5:15 pm

1 stop4h 40m

$185

CharlestonBuffalo

CHS - BUF

CHSBUF

Charleston

Tue 1/20

6:23 pm-10:59 pm

1 stop4h 36m

Buffalo

Sat 1/24

11:51 am-5:13 pm

1 stop5h 22m

$197

CharlestonBuffalo

CHS - BUF

CHSBUF

Charleston

Sat 11/15

6:50 pm-10:58 pm

1 stop4h 08m

Buffalo

Wed 11/19

7:00 am-1:55 pm

1 stop6h 55m

$197

CharlestonBuffalo

CHS - BUF

CHSBUF

Charleston

Fri 1/9

6:00 am-11:11 am

1 stop5h 11m

Buffalo

Sun 1/11

6:03 am-10:59 am

1 stop4h 56m

$197

CharlestonBuffalo

CHS - BUF

CHSBUF

Charleston

Thu 1/1

8:08 pm-11:59 pm

1 stop3h 51m

Buffalo

Mon 1/5

7:15 pm-12:05 am

1 stop4h 50m

$201

CharlestonBuffalo

CHS - BUF

CHSBUF

Charleston

Fri 11/28

6:00 am-12:33 pm

1 stop6h 33m

Buffalo

Fri 12/5

6:35 pm-11:13 pm

1 stop4h 38m

$203

SavannahBuffalo

SAV - BUF

SAVBUF

Savannah/Hilton Head

Sat 12/13

8:24 pm-12:07 am

1 stop3h 43m

Buffalo

Sun 12/14

5:27 am-12:31 pm

2 stops7h 04m

$204

SavannahBuffalo

SAV - BUF

SAVBUF

Savannah/Hilton Head

Tue 11/25

10:51 am-6:45 pm

1 stop7h 54m

Buffalo

Wed 12/3

7:05 am-12:01 pm

1 stop4h 56m

$205

CharlestonBuffalo

CHS - BUF

CHSBUF

Charleston

Thu 3/26

12:05 pm-8:21 pm

1 stop8h 16m

Buffalo

Mon 3/30

3:20 pm-11:07 pm

1 stop7h 47m

$213

SavannahBuffalo

SAV - BUF

SAVBUF

Savannah/Hilton Head

Fri 2/13

7:20 pm-11:44 pm

1 stop4h 24m

Buffalo

Sun 2/15

6:32 pm-11:26 pm

1 stop4h 54m

$223

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 60 results
1
2
3
...
6

Best time to book a flight from South Carolina to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Buffalo

What is the cheapest month to book a flight from South Carolina to Buffalo?

Currently, October is the cheapest month in which you can book a flight from South Carolina to Buffalo (average of $80). Flying from South Carolina to Buffalo in August is currently the most expensive (average of $203). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to BUF?

Find hourly flight availability from South Carolina to Buffalo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 31, 2025.

Unlike in the evening, when flights are generally more expensive, you can save up to 6% on flights from South Carolina to Buffalo by exploring options for tickets at noon.

What is the cheapest day to fly from South Carolina to Buffalo?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Buffalo. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their South Carolina to Buffalo flight should consider departing on Wednesday at noon when fares are most often at their lowest. Friday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Buffalo from South Carolina?

    Most people fly into Buffalo (BUF) if they book a flight to Buffalo from South Carolina. Buffalo is conveniently located just 8.3 mi from Buffalo’s city center.

  • How long is the flight from South Carolina to Buffalo?

    Departing from South Carolina to Buffalo will take you 4h 08m. The distance from South Carolina to Buffalo is about 697 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from South Carolina to Buffalo one-way?

    $91 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on JetBlue and Delta, with prices starting from $98 and $99, respectively.

  • What are the most popular routes from South Carolina to Buffalo?

    The most popular flight routes from South Carolina to Buffalo are Charlotte Douglas - Buffalo, Charleston - Buffalo and Greenville - Buffalo.

  • Can I find deals for flights from South Carolina to Buffalo that include hotel bookings?

    Yes. In addition to deals on South Carolina to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Buffalo.

  • Can I find deals for business class flights from South Carolina to Buffalo?

    Yes. Cheapflights offers flight deals from South Carolina to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Buffalo?

    Currently, October is the cheapest month in which you can book a flight from South Carolina to Buffalo (average of $80). Flying from South Carolina to Buffalo in August is currently the most expensive (average of $203). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Lockport
Cheektowaga
Orchard Park
Batavia
Williamsville
Eden
Amherst
West Seneca

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Buffalo

See prices for flight routes from nearby airports that may be better suited for you.
Los Angeles to John F Kennedy Intl flights
Dallas/Fort Worth to John F Kennedy Intl flights
Los Angeles to Newark flights
Dallas/Fort Worth to LaGuardia flights
San Francisco to John F Kennedy Intl flights
O'Hare Intl to John F Kennedy Intl flights
Dallas/Fort Worth to Newark flights
Fort Lauderdale to Newark flights
San Francisco to Newark flights
Hobby to LaGuardia flights
Atlanta to John F Kennedy Intl flights
Los Angeles to LaGuardia flights
Fort Lauderdale to John F Kennedy Intl flights
Hobby to John F Kennedy Intl flights
Orlando to John F Kennedy Intl flights
O'Hare Intl to LaGuardia flights
Hobby to Newark flights
Atlanta to LaGuardia flights
Seattle to John F Kennedy Intl flights
Atlanta to Newark flights
Tampa to LaGuardia flights
O'Hare Intl to Newark flights
Tampa to John F Kennedy Intl flights
Fort Lauderdale to LaGuardia flights
Miami to John F Kennedy Intl flights
Miami to Newark flights
Denver to John F Kennedy Intl flights
Raleigh to John F Kennedy Intl flights
San Francisco to LaGuardia flights
George Bush Intcntl to John F Kennedy Intl flights
Miami to LaGuardia flights
Austin to John F Kennedy Intl flights
George Bush Intcntl to Newark flights
Detroit to John F Kennedy Intl flights
Charlotte to John F Kennedy Intl flights
Minneapolis to John F Kennedy Intl flights
San Diego to John F Kennedy Intl flights
George Bush Intcntl to LaGuardia flights
Orlando to Newark flights
Sky Harbor Intl to John F Kennedy Intl flights
Orlando to LaGuardia flights
Tampa to Newark flights
Denver to LaGuardia flights
Charlotte to LaGuardia flights
Raleigh to LaGuardia flights
Seattle to Newark flights
Denver to Newark flights
Austin to Newark flights
Boston to LaGuardia flights
Indianapolis to John F Kennedy Intl flights

Top 5 airlines flying from South Carolina to Buffalo

Discover the top 5 airlines that operate flights from South Carolina to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$135Average$211FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$195Average$336FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$198Average$313FlexibilityNo cancel feeOn-time69%
DeltaCheapest$216Average$308FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$236Average$377FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.