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$81+ Cheap flights from South Carolina to Buffalo (BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/15. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — BUF
jun. 17 — jun. 241
mar. 6/17
mar. 6/24
1 adult, Economy
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Cheap flight deals from South Carolina to Buffalo

Keep the following information in mind while searching for South Carolina to Buffalo flight deals. Data was last updated junio 12, 2025.

Round-trip from

$192
(JetBlue)

One-way from

$81
(JetBlue)

Popular in

February

Cheapest in

September

Average price

$376
From South Carolina to Buffalo
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One-way flight from South Carolina to Buffalo
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Highest demand for flights based on searches. 0% potential increase in price ($1 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from South Carolina to Buffalo

Cheapest flights from South Carolina to Buffalo
Explore the most affordable flight options available from South Carolina to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

This JetBlue deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/1212:05 pmCHS - BUF
1 stop7h 16mJetBlue
mié. 11/199:15 amBUF - CHS
1 stop8h 07mJetBlue
Deal found 6/10$161
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 10/97:59 pmCHS - BUF
1 stop3h 55mDelta
mié. 10/156:16 amBUF - CHS
1 stop6h 36mDelta
Deal found 6/10$217
This Southwest deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/318:05 amCHS - BUF
1 stop3h 55mSouthwest
lun. 11/35:45 amBUF - CHS
1 stop4h 15mSouthwest
Deal found 6/12$218
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/76:00 amCHS - BUF
1 stop5h 04mAmerican Airlines
dom. 8/106:15 amBUF - CHS
1 stop6h 01mAmerican Airlines
Deal found 6/10$227
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/76:14 pmMYR - BUF
1 stop5h 55mAmerican Airlines
lun. 8/116:33 pmBUF - MYR
1 stop4h 38mAmerican Airlines
Deal found 6/11$233
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/136:00 amCHS - BUF
1 stop5h 33mUnited Airlines
mar. 11/1810:37 amBUF - CHS
2 stops8h 46mUnited Airlines
Deal found 6/12$234
This JetBlue deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/151:35 pmSAV - BUF
1 stop7h 39mJetBlue
mar. 7/2210:54 amBUF - SAV
1 stop6h 36mJetBlue
Deal found 6/10$249
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 7/56:04 pmCAE - BUF
1 stop6h 28mAmerican Airlines
mar. 7/85:30 amBUF - CAE
1 stop4h 41mAmerican Airlines
Deal found 6/11$249
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/111:31 amHHH - BUF
1 stop5h 45mAmerican Airlines
mar. 11/46:23 amBUF - HHH
1 stop3h 52mAmerican Airlines
Deal found 6/11$249
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 7/127:37 pmCLT - BUF
1 stop5h 16mDelta
mar. 7/226:30 amBUF - CLT
1 stop5h 21mDelta
Deal found 6/12$251
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 7/44:43 pmCLT - BUF
Nonstop1h 47mAmerican Airlines
sáb. 7/196:20 amBUF - CLT
Nonstop1h 57mAmerican Airlines
Deal found 6/11$253
This CheapOair deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/261:56 pmCLT - BUF
1 stop28h 20mFrontier
dom. 9/282:47 pmBUF - CLT
1 stop19h 03mFrontier
Deal found 6/10$256

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
Use the filters below to find and compare flights from South Carolina to Buffalo that are best for you.

Fly from

South Carolina

Fly to

Buffalo

Route

Depart

Return

Price

CharlestonBuffalo

CHS - BUF

CHSBUF

Charleston

mar. 6/24

6:59 pm-11:59 pm

1 stop5h 00m

Buffalo

mié. 7/16

7:22 am-12:24 pm

1 stop5h 02m

$192

CharlestonBuffalo

CHS - BUF

CHSBUF

Charleston

lun. 6/30

7:52 pm-11:46 pm

1 stop3h 54m

Buffalo

lun. 7/7

6:28 am-12:56 pm

1 stop6h 28m

$218

Myrtle BeachBuffalo

MYR - BUF

MYRBUF

Myrtle Beach Intl

jue. 8/7

6:14 pm-12:09 am

1 stop5h 55m

Buffalo

lun. 8/11

6:33 pm-11:11 pm

1 stop4h 38m

$233

SavannahBuffalo

SAV - BUF

SAVBUF

Savannah/Hilton Head

mar. 7/15

1:35 pm-9:14 pm

1 stop7h 39m

Buffalo

mar. 7/22

10:54 am-5:30 pm

1 stop6h 36m

$249

ColumbiaBuffalo

CAE - BUF

CAEBUF

Columbia Metropolitan

sáb. 7/5

6:04 pm-12:32 am

1 stop6h 28m

Buffalo

mar. 7/8

5:30 am-10:11 am

1 stop4h 41m

$249

Hilton Head IslandBuffalo

HHH - BUF

HHHBUF

Hilton Head Island

sáb. 11/1

11:31 am-5:16 pm

1 stop5h 45m

Buffalo

mar. 11/4

6:23 am-10:15 am

1 stop3h 52m

$249

CharlotteBuffalo

CLT - BUF

CLTBUF

Charlotte Douglas

sáb. 7/12

7:37 pm-12:53 am

1 stop5h 16m

Buffalo

mar. 7/22

6:30 am-11:51 am

1 stop5h 21m

$251

CharlotteBuffalo

CLT - BUF

CLTBUF

Charlotte Douglas

vie. 7/4

4:43 pm-6:30 pm

Nonstop1h 47m

Buffalo

sáb. 7/12

6:20 am-8:17 am

Nonstop1h 57m

$253

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

lun. 8/4

6:25 pm-11:44 pm

1 stop5h 19m

Buffalo

lun. 8/11

6:04 am-10:24 am

1 stop4h 20m

$257

GreenvilleBuffalo

GSP - BUF

GSPBUF

Greenville

lun. 9/8

6:02 am-9:45 am

1 stop3h 43m

Buffalo

mar. 9/16

10:38 am-9:01 pm

2 stops10h 23m

$262

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/9

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Buffalo

What is the cheapest month to book a flight from South Carolina to Buffalo?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Buffalo (average of $256). Flying from South Carolina to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to BUF?

Find hourly flight availability from South Carolina to Buffalo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated junio 12, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Buffalo as you normally would.

Rainfall in Buffalo by month

Plan your trip to Buffalo by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Buffalo ranges from 2.5 - 4.0 inches per month. November is typically the wettest month, when rainfall can reach 4.0 in. February is typically the driest time to visit Buffalo when rainfall is around 2.5 in.

Temperature in Buffalo by month

Plan your trip to Buffalo by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Buffalo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 24.8 F).

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated junio 12, 2025.
To help decide which airline to fly from South Carolina to Buffalo, see what other customers have to say about Southwest, Delta and United Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Southwest
8.0
Very good
4,287 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Delta
8.0
Very good
7,950 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
United Airlines
7.4
Good
8,790 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
JetBlue
7.3
Good
2,925 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Boarding

8.2

Entertainment

7.6

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Buffalo from South Carolina?

    Most people fly into Buffalo (BUF) if they book a flight to Buffalo from South Carolina. Buffalo is conveniently located just 8.3 mi from Buffalo’s city center.

  • What are the cheapest airlines to fly from South Carolina to Buffalo one-way?

    $81 is the cheapest one-way deal found within the past few days, from JetBlue. You may also be able to find cheap deals on American Airlines and Delta, with prices starting from $100 and $114, respectively.

  • What are the most popular routes from South Carolina to Buffalo?

    The most popular flight routes from South Carolina to Buffalo are Charlotte Douglas - Buffalo, Charleston - Buffalo and Greenville - Buffalo.

  • Can I find deals for flights from South Carolina to Buffalo that include hotel bookings?

    Yes. In addition to deals on South Carolina to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Buffalo.

  • Can I find deals for business class flights from South Carolina to Buffalo?

    Yes. Cheapflights offers flight deals from South Carolina to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Buffalo?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Buffalo (average of $256). Flying from South Carolina to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near South Carolina?

Book flights to South Carolina if you plan to visit one of these locations
Williamsville
Amherst
Orchard Park
Batavia
Eden
Cheektowaga
West Seneca

Browse thousands of different options on Cheapflights for your next trip

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Top 5 airlines flying from South Carolina to Buffalo

Discover the top 5 airlines that operate flights from South Carolina to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$198Average$364FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$200Average$337FlexibilityNo cancel feeOn-time71%
JetBlueCheapest$200Average$258FlexibilityNo cancel feeOn-time62%
DeltaCheapest$207Average$309FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$233Average$365FlexibilityNo cancel feeOn-time63%

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