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$100+ Cheap flights from Missouri to Buffalo (BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/17. Fares are subject to change and may not be available on all flights or dates of travel.
STL — BUF
May 6 — May 131
Tue 5/6
Tue 5/13
1 adult, Economy
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Cheap flight deals from Missouri to Buffalo

Keep the following information in mind while searching for Missouri to Buffalo flight deals. Data was last updated May 1, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$208
(Booking.com)

One-way from

$100
(Booking.com)

Popular in

November

Cheapest in

January

Average price

$451
Provider with most accurate pricing for Kansas City-Buffalo flight deals.
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Provider most trusted by Cheapflights users for Kansas City-Buffalo flights.
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From Missouri to Buffalo
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One-way flight from Missouri to Buffalo
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Highest demand for flights based on searches. 3% potential increase in price ($15 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in May 2025
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Find flight deals from Missouri to Buffalo

Cheapest flights from Missouri to Buffalo
Explore the most affordable flight options available from Missouri to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

This Booking.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/145:45 pmSTL - BUF
1 stop14h 16mFrontier
Mon 5/199:51 amBUF - STL
1 stop15h 15mFrontier
Deal found 4/29$208
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/45:20 pmSTL - BUF
1 stop5h 18mUnited Airlines
Wed 7/95:54 pmBUF - STL
1 stop5h 51mUnited Airlines
Deal found 4/30$244
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/35:40 pmSTL - BUF
1 stop5h 15mDelta
Fri 6/66:00 amBUF - STL
1 stop7h 04mDelta
Deal found 4/30$251
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/225:12 amSTL - BUF
1 stop7h 00mAmerican Airlines
Thu 5/2910:11 amBUF - STL
1 stop3h 56mAmerican Airlines
Deal found 4/29$262
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/122:20 pmSTL - BUF
2 stops7h 40mSouthwest
Tue 7/156:15 amBUF - STL
2 stops6h 20mSouthwest
Deal found 4/30$309
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/294:34 pmMCI - BUF
1 stop5h 26mAmerican Airlines
Sun 8/317:00 amBUF - MCI
1 stop8h 02mAmerican Airlines
Deal found 4/30$311
This Southwest deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/217:10 amMCI - BUF
1 stop3h 55mSouthwest
Sun 8/245:45 amBUF - MCI
1 stop4h 55mSouthwest
Deal found 4/30$335
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/223:23 pmMCI - BUF
1 stop4h 53mUnited Airlines
Tue 8/265:54 pmBUF - MCI
1 stop4h 48mUnited Airlines
Deal found 4/30$381
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/76:37 amMCI - BUF
1 stop4h 33mDelta
Sat 5/105:54 pmBUF - MCI
1 stop4h 43mDelta
Deal found 4/30$527

Cheapflights Fare Finder

Customize your flight search to find flights from Missouri to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
Use the filters below to find and compare flights from Missouri to Buffalo that are best for you.

Fly from

Missouri

Fly to

Buffalo

Route

Depart

Return

Price

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Wed 5/14

5:45 pm-9:01 am

1 stop14h 16m

Buffalo

Mon 5/19

9:51 am-12:06 am

1 stop15h 15m

$208

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Fri 7/4

5:20 pm-11:38 pm

1 stop5h 18m

Buffalo

Wed 7/9

5:54 pm-10:45 pm

1 stop5h 51m

$244

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Tue 6/3

5:40 pm-11:55 pm

1 stop5h 15m

Buffalo

Fri 6/6

6:00 am-12:04 pm

1 stop7h 04m

$251

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Thu 5/22

5:12 am-1:12 pm

1 stop7h 00m

Buffalo

Thu 5/29

10:11 am-1:07 pm

1 stop3h 56m

$262

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Sat 7/12

2:20 pm-11:00 pm

2 stops7h 40m

Buffalo

Tue 7/15

6:15 am-11:35 am

2 stops6h 20m

$309

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

Fri 5/23

6:50 am-6:05 pm

1 stop10h 15m

Buffalo

Mon 5/26

5:45 am-10:35 am

1 stop5h 50m

$395

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

Fri 6/13

5:45 pm-11:46 pm

1 stop5h 01m

Buffalo

Fri 6/20

5:51 pm-11:15 pm

1 stop6h 24m

$421

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

Fri 5/16

5:45 pm-11:53 pm

1 stop5h 08m

Buffalo

Mon 5/19

5:10 am-11:40 am

1 stop7h 30m

$427

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

Wed 5/7

6:37 am-12:10 pm

1 stop4h 33m

Buffalo

Sat 5/10

5:54 pm-9:37 pm

1 stop4h 43m

$527

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Sat 5/17

5:45 pm-9:01 am

1 stop14h 16m

$100

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 19 results
1
2

Best time to book a flight from Missouri to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Buffalo

What is the cheapest month to book a flight from Missouri to Buffalo?

Currently, January is the cheapest month in which you can book a flight from Missouri to Buffalo (average of $256). Flying from Missouri to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to BUF?

Find hourly flight availability from Missouri to Buffalo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Buffalo as you normally would.

Rainfall in Buffalo by month

Plan your trip to Buffalo by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Buffalo ranges from 2.5 - 4.0 inches per month. November is typically the wettest month, when rainfall can reach 4.0 in. February is typically the driest time to visit Buffalo when rainfall is around 2.5 in.

Temperature in Buffalo by month

Plan your trip to Buffalo by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Buffalo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 24.8 F).

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated May 1, 2025.
Read through reviews of airlines operating flights from Missouri to Buffalo, such as Southwest, Delta and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,294 reviews

Overall

8.0

Comfort

8.0

Boarding

8.2

Food

7.1

Crew

8.6

Entertainment

7.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Southwest
8.0
Very good
4,294 reviews
Southwest
8.0
Very good
4,294 reviews

Overall

8.0

Comfort

8.0

Boarding

8.2

Food

7.1

Crew

8.6

Entertainment

7.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Delta
8.0
Very good
7,934 reviews
Southwest
8.0
Very good
4,294 reviews

Overall

8.0

Comfort

8.0

Boarding

8.2

Food

7.1

Crew

8.6

Entertainment

7.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
United Airlines
7.4
Good
8,696 reviews
Southwest
8.0
Very good
4,294 reviews

Overall

8.0

Comfort

8.0

Boarding

8.2

Food

7.1

Crew

8.6

Entertainment

7.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,294 reviews

Overall

8.0

Comfort

8.0

Boarding

8.2

Food

7.1

Crew

8.6

Entertainment

7.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Frontier
6.0
Okay
3,287 reviews
Southwest
8.0
Very good
4,294 reviews

Overall

8.0

Comfort

8.0

Boarding

8.2

Food

7.1

Crew

8.6

Entertainment

7.6

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Related info for your journey

Find useful and relevant information for your journey from Missouri to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Buffalo from Missouri?

    Most people fly into Buffalo (BUF) if they book a flight to Buffalo from Missouri. Buffalo is conveniently located just 8.3 mi from Buffalo’s city center.

  • What are the cheapest airlines to fly from Missouri to Buffalo one-way?

    One-way options have recently been found by users for as low as $100 on Frontier. Other airlines that offer cheap prices include Delta from $126 and United Airlines from $131 one-way.

  • What are the most popular routes from Missouri to Buffalo?

    While some choose either Lambert-St Louis - Buffalo or Springfield-Branson - Buffalo, Kansas City - Buffalo is the most popular route from Missouri to Buffalo.

  • Can I find deals for flights from Missouri to Buffalo that include hotel bookings?

    Yes. In addition to deals on Missouri to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Buffalo.

  • Can I find deals for business class flights from Missouri to Buffalo?

    Yes. Cheapflights offers flight deals from Missouri to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Buffalo?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Buffalo (average of $256). Flying from Missouri to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Missouri?

Book flights to Missouri if you plan to visit one of these locations
Williamsville
Amherst
West Seneca
Batavia
Orchard Park
Cheektowaga

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See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Missouri to Buffalo

Discover the top 5 airlines that operate flights from Missouri to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$137Average$176FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$179Average$433FlexibilityNo cancel feeOn-time69%
DeltaCheapest$200Average$387FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$228Average$428FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$306Average$402FlexibilityNo cancel feeOn-time63%

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