How long is the flight from Missouri to Buffalo?

Airlines like Frontier, American Airlines, and Delta fly from Missouri to Buffalo in about 5h 28m. The time it takes to get you to your destination can typically vary by up to 50m. The distance from Missouri to Buffalo is about 867 mi. This flight may include one or multiple stops.

What are the cheapest airlines to fly from Missouri to Buffalo one-way?

One-way options have recently been found by users for as low as $95 on American Airlines. Other airlines that offer cheap prices include United Airlines from $109 and Southwest from $118 one-way.

In terms of precipitation, rainfall in Buffalo ranges from 2.5 - 4.0 inches per month. November is typically the wettest month, when rainfall can reach 4.0 in. February is typically the driest time to visit Buffalo when rainfall is around 2.5 in.

If weather is an important factor for your trip to Buffalo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 24.8 F).

What are the most popular routes from Missouri to Buffalo?

While some choose either Kansas City - Buffalo or Springfield-Branson - Buffalo, Lambert-St Louis - Buffalo is the most popular route from Missouri to Buffalo.

What are the most popular airlines that fly from Missouri to Buffalo?

The most popular airlines flying from Missouri to Buffalo are American Airlines, Southwest and Delta. Something to consider prior to booking your flight.

What airport do you fly into for flights to Buffalo from Missouri?

Most people fly into Buffalo (BUF) if they book a flight to Buffalo from Missouri. Buffalo is conveniently located just 8.3 mi from Buffalo’s city center.

Can I find deals for flights from Missouri to Buffalo that include hotel bookings?

Yes. In addition to deals on Missouri to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Missouri to Buffalo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Buffalo.

Can I find deals for business class flights from Missouri to Buffalo?

Yes. Cheapflights offers flight deals from Missouri to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$90+ Flights from Missouri to Buffalo

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Cheap flight deals from Missouri to Buffalo

Cheapest flights from Missouri to Buffalo
Explore the most affordable flight options available from Missouri to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Wed 12/318:29 amSGF - BUF

1 stop7h 09mAmerican Airlines

Sun 1/46:29 pmBUF - SGF

1 stop4h 59mAmerican Airlines

Deal found 12/16

$309

Wed 12/315:42 pmMCI - BUF

1 stop3h 51mDelta

Sun 1/46:10 amBUF - MCI

1 stop4h 46mDelta

Deal found 12/15

$368

Tue 12/233:10 pmCOU - BUF

1 stop4h 44mUnited Airlines

Sat 12/275:35 pmBUF - COU

1 stop4h 44mUnited Airlines

Deal found 12/16

$372

Wed 12/318:05 amCOU - BUF

1 stop4h 19mUnited Airlines

Sun 1/45:35 pmBUF - COU

1 stop4h 44mUnited Airlines

Deal found 12/16

$439

Tue 12/306:35 pmSTL - BUF

1 stop4h 24mAmerican Airlines

Sat 1/37:15 pmBUF - STL

1 stop5h 41mAmerican Airlines

Deal found 12/16

$447

Wed 12/315:04 amMCI - BUF

2 stops10h 20mAmerican Airlines

Sun 1/46:29 pmBUF - MCI

1 stop8h 09mAmerican Airlines

Deal found 12/15

$469

Wed 12/317:40 amMCI - BUF

1 stop4h 44mUnited Airlines

Sun 1/46:30 amBUF - MCI

1 stop5h 13mUnited Airlines

Deal found 12/16

$474

Tue 12/233:20 pmCOU - BUF

1 stop6h 13mAmerican Airlines

Sat 12/276:29 pmBUF - COU

1 stop4h 30mAmerican Airlines

Deal found 12/15

$474

Sun 12/285:59 pmSTL - BUF

1 stop4h 29mDelta

Sun 1/46:10 amBUF - STL

1 stop4h 14mDelta

Deal found 12/16

$512

Sun 12/285:40 amSTL - BUF

2 stops7h 55mSouthwest

Sun 1/48:40 pmBUF - STL

1 stop4h 25mSouthwest

Deal found 12/16

$517

Mon 12/226:15 pmMCI - BUF

2 stops49h 25mMultiple Airlines

Sat 1/39:28 amBUF - MCI

1 stop14h 31mMultiple Airlines

Deal found 12/16

$571

Tue 12/236:10 pmMCI - BUF

1 stop4h 55mSouthwest

Tue 12/305:00 amBUF - MCI

2 stops10h 55mSouthwest

Deal found 12/15

$572

Best flights from Missouri to Buffalo
Discover carefully curated flight deals from Missouri to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 18, 2025.

Fri 1/3011:18 amSTL - BUF

1 stop6h 18mFrontier

Sat 1/3112:29 pmBUF - STL

1 stop12h 04mFrontier

Deal found 12/16

$238

Tue 1/65:00 pmSGF - BUF

1 stop5h 48mAmerican Airlines

Mon 1/127:00 amBUF - SGF

1 stop6h 15mAmerican Airlines

Deal found 12/16

$260

Fri 1/305:00 pmSGF - BUF

1 stop5h 28mDelta

Sun 2/112:13 pmBUF - SGF

1 stop5h 02mDelta

Deal found 12/17

$269

Sat 1/313:14 pmSGF - BUF

1 stop4h 15mUnited Airlines

Tue 2/35:23 pmBUF - SGF

1 stop5h 35mUnited Airlines

Deal found 12/15

$321

Fri 1/911:06 amMCI - BUF

2 stops29h 32mMultiple Airlines

Mon 1/129:08 amBUF - MCI

1 stop8h 01mMultiple Airlines

Deal found 12/16

$327

Fri 1/306:05 amSTL - BUF

2 stops8h 05mSouthwest

Sat 1/313:35 pmBUF - STL

2 stops6h 20mSouthwest

Deal found 12/16

$350

Sun 1/44:27 pmSGF - BUF

1 stop6h 32mAmerican Airlines

Sun 1/116:53 amBUF - SGF

1 stop6h 21mAmerican Airlines

Deal found 12/16

$274

Fri 3/67:52 amSTL - BUF

1 stop11h 38mFrontier

Sun 3/89:25 pmBUF - STL

1 stop10h 42mFrontier

Deal found 12/16

$300

Fri 1/3012:45 pmSGF - BUF

2 stops8h 58mAmerican Airlines

Sun 2/16:53 amBUF - SGF

1 stop6h 21mAmerican Airlines

Deal found 12/17

$274

Tue 3/3110:02 amSTL - BUF

1 stop4h 57mDelta

Wed 4/16:02 amBUF - STL

1 stop7h 17mDelta

Deal found 12/16

$317

Wed 1/143:10 pmCOU - BUF

1 stop4h 19mUnited Airlines

Sat 1/178:30 amBUF - COU

1 stop7h 05mUnited Airlines

Deal found 12/14

$328

Wed 3/115:15 pmSTL - BUF

1 stop4h 59mDelta

Mon 3/161:00 pmBUF - STL

1 stop4h 42mDelta

Deal found 12/16

$319

Sat 1/173:10 pmCOU - BUF

1 stop4h 19mUnited Airlines

Wed 1/2110:45 amBUF - COU

1 stop4h 50mUnited Airlines

Deal found 12/15

$328

Wed 12/318:29 amSGF - BUF

1 stop7h 09mAmerican Airlines

Sun 1/46:29 pmBUF - SGF

1 stop4h 59mAmerican Airlines

Deal found 12/16

$309

Wed 4/16:10 amSTL - BUF

1 stop7h 09mDelta

Mon 4/64:57 pmBUF - STL

1 stop7h 45mDelta

Deal found 12/16

$342

Tue 3/318:30 amSTL - BUF

2 stops8h 51mUnited Airlines

Sun 4/57:00 amBUF - STL

1 stop4h 35mUnited Airlines

Deal found 12/16

$347

Tue 3/319:45 amSTL - BUF

1 stop5h 58mDelta

Sun 4/54:57 pmBUF - STL

1 stop5h 13mDelta

Deal found 12/16

$342

Tue 3/315:59 pmSTL - BUF

1 stop3h 56mDelta

Sat 4/44:57 pmBUF - STL

1 stop7h 45mDelta

Deal found 12/16

$342

Fri 1/911:29 amMCI - BUF

2 stops10h 02mUnited Airlines

Mon 1/122:49 pmBUF - MCI

2 stops8h 10mUnited Airlines

Deal found 12/16

$379

Tue 6/26:07 amMCI - BUF

1 stop4h 38mAmerican Airlines

Wed 6/106:34 amBUF - MCI

1 stop4h 41mAmerican Airlines

Deal found 12/14

$387

Tue 3/3110:02 amSTL - BUF

1 stop4h 57mDelta

Thu 4/212:06 pmBUF - STL

1 stop6h 47mDelta

Deal found 12/16

$342

Thu 1/811:29 amMCI - BUF

1 stop4h 15mUnited Airlines

Mon 1/122:49 pmBUF - MCI

1 stop6h 07mUnited Airlines

Deal found 12/14

$391

Wed 12/315:42 pmMCI - BUF

1 stop3h 51mDelta

Sun 1/46:10 amBUF - MCI

1 stop4h 46mDelta

Deal found 12/15

$368

Wed 12/318:05 amCOU - BUF

1 stop4h 19mUnited Airlines

Sun 1/45:35 pmBUF - COU

1 stop4h 44mUnited Airlines

Deal found 12/16

$439

Sun 3/86:35 amMCI - BUF

1 stop4h 09mDelta

Fri 3/136:15 amBUF - MCI

1 stop4h 36mDelta

Deal found 12/16

$387

Sat 6/65:00 pmMCI - BUF

1 stop5h 57mDelta

Thu 6/117:40 pmBUF - MCI

1 stop5h 15mDelta

Deal found 12/15

$387

Last-minute flights from Missouri to Buffalo
Discover last-minute flight deals from Missouri to Buffalo. Data last updated December 18, 2025 and is based on user searches.

Wed 12/318:29 amSGF - BUF

1 stop7h 09mAmerican Airlines

Sun 1/46:29 pmBUF - SGF

1 stop4h 59mAmerican Airlines

Deal found 12/16

$309

Wed 12/315:42 pmMCI - BUF

1 stop3h 51mDelta

Sun 1/46:10 amBUF - MCI

1 stop4h 46mDelta

Deal found 12/15

$368

Sun 1/44:27 pmSGF - BUF

1 stop6h 32mAmerican Airlines

Sun 1/116:53 amBUF - SGF

1 stop6h 21mAmerican Airlines

Deal found 12/16

$274

Tue 1/65:00 pmSGF - BUF

1 stop5h 48mAmerican Airlines

Mon 1/127:00 amBUF - SGF

1 stop6h 15mAmerican Airlines

Deal found 12/16

$260

Fri 1/911:06 amMCI - BUF

2 stops29h 32mMultiple Airlines

Mon 1/129:08 amBUF - MCI

1 stop8h 01mMultiple Airlines

Deal found 12/16

$327

Sat 1/173:10 pmCOU - BUF

1 stop4h 19mUnited Airlines

Wed 1/2110:45 amBUF - COU

1 stop4h 50mUnited Airlines

Deal found 12/16

$328

Thu 1/2210:55 amMCI - BUF

1 stop4h 25mSouthwest

Sun 1/255:50 amBUF - MCI

1 stop4h 45mSouthwest

Deal found 12/16

$359

Fri 1/3011:18 amSTL - BUF

1 stop6h 18mFrontier

Sat 1/3112:29 pmBUF - STL

1 stop12h 04mFrontier

Deal found 12/16

$238

Fri 1/305:00 pmSGF - BUF

1 stop5h 28mDelta

Sun 2/112:13 pmBUF - SGF

1 stop5h 02mDelta

Deal found 12/17

$269

Fri 1/303:54 pmSTL - BUF

1 stop6h 47mAmerican Airlines

Sat 1/319:41 amBUF - STL

2 stops8h 20mAmerican Airlines

Deal found 12/16

$317

Fri 1/306:05 amSTL - BUF

2 stops8h 05mSouthwest

Sat 1/313:35 pmBUF - STL

2 stops6h 20mSouthwest

Deal found 12/16

$350

Sat 1/313:14 pmSGF - BUF

1 stop4h 15mUnited Airlines

Tue 2/35:23 pmBUF - SGF

1 stop5h 35mUnited Airlines

Deal found 12/15

$321

One-way flights from Missouri to Buffalo
Search for one-way flight options from Missouri to Buffalo. Find affordable one-way fares based on user searches. Data last updated December 18, 2025.

Wed 1/75:11 pmSTL - BUF

1 stop14h 02mFrontier

Deal found 12/16

$90

Wed 1/285:04 pmMCI - BUF

2 stops18h 40mMultiple Airlines

Deal found 12/15

$120

Sat 1/105:39 pmSGF - BUF

1 stop5h 14mAmerican Airlines

Deal found 12/16

$126

Wed 1/78:05 amSTL - BUF

2 stops10h 20mUnited Airlines

Deal found 12/16

$134

Wed 3/119:45 amSTL - BUF

1 stop5h 58mDelta

Deal found 12/17

$136

Wed 1/75:11 pmSTL - BUF

3 stops39h 20mMultiple Airlines

Deal found 12/16

$143

Wed 3/1110:00 amSTL - BUF

2 stops7h 42mUnited Airlines

Deal found 12/17

$176

Fri 3/205:59 pmSTL - BUF

1 stop3h 56mDelta

Deal found 12/16

$184

Sat 3/216:32 amSTL - BUF

1 stop4h 12mDelta

Deal found 12/16

$194

Fri 2/66:00 amMCI - BUF

1 stop5h 08mAmerican Airlines

Deal found 12/16

$194

Thu 1/155:00 pmSGF - BUF

1 stop5h 48mAmerican Airlines

Deal found 12/15

$196

Fri 3/202:35 pmSTL - BUF

2 stops8h 35mSouthwest

Deal found 12/16

$209

Find flight deals from Missouri to Buffalo

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$238 (Frontier)
One-way from	$90 (Kiwi.com)
Popular in	December
Cheapest in	January
Average price	$516

Provider with most accurate pricing for Lambert-St Louis-Buffalo flight deals.

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Provider most trusted by Cheapflights users for Lambert-St Louis-Buffalo flights.

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From Missouri to Buffalo

Search Deals

One-way flight from Missouri to Buffalo

Search Deals

Highest demand for flights based on searches. 4% potential increase in price ($15 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 3% potential price decrease ($13 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Fri 1/30

11:18 am-6:36 pm

1 stop6h 18m

Buffalo

Sat 1/31

12:29 pm-11:33 pm

1 stop12h 04m

$238

SpringfieldBuffalo

SGF - BUF

SGFBUF

Springfield-Branson

Tue 1/6

5:00 pm-11:48 pm

1 stop5h 48m

Buffalo

Mon 1/12

7:00 am-12:15 pm

1 stop6h 15m

$260

SpringfieldBuffalo

SGF - BUF

SGFBUF

Springfield-Branson

Fri 1/30

5:00 pm-11:28 pm

1 stop5h 28m

Buffalo

Sun 2/1

12:13 pm-4:15 pm

1 stop5h 02m

$269

SpringfieldBuffalo

SGF - BUF

SGFBUF

Springfield-Branson

Sun 1/4

4:27 pm-11:59 pm

1 stop6h 32m

Buffalo

Sun 1/11

6:53 am-12:14 pm

1 stop6h 21m

$274

SpringfieldBuffalo

SGF - BUF

SGFBUF

Springfield-Branson

Fri 1/30

12:45 pm-10:43 pm

2 stops8h 58m

Buffalo

Sun 2/1

6:53 am-12:14 pm

1 stop6h 21m

$274

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Fri 3/6

7:52 am-8:30 pm

1 stop11h 38m

Buffalo

Sun 3/8

9:25 pm-7:07 am

1 stop10h 42m

$300

SpringfieldBuffalo

SGF - BUF

SGFBUF

Springfield-Branson

Wed 12/31

8:29 am-4:38 pm

1 stop7h 09m

Buffalo

Sun 1/4

6:29 pm-10:28 pm

1 stop4h 59m

$309

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Tue 3/31

10:02 am-3:59 pm

1 stop4h 57m

Buffalo

Wed 4/1

6:02 am-12:19 pm

1 stop7h 17m

$317

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Wed 3/11

5:15 pm-11:14 pm

1 stop4h 59m

Buffalo

Mon 3/16

1:00 pm-4:42 pm

1 stop4h 42m

$319

SpringfieldBuffalo

SGF - BUF

SGFBUF

Springfield-Branson

Sat 1/31

3:14 pm-8:29 pm

1 stop4h 15m

Buffalo

Tue 2/3

5:23 pm-9:58 pm

1 stop5h 35m

$321

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 42 results

...

Best time to book a flight from Missouri to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Missouri with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Buffalo

What is the cheapest month to book a flight from Missouri to Buffalo?

Currently, March is the cheapest month in which you can book a flight from Missouri to Buffalo (average of $136). Flying from Missouri to Buffalo in October is currently the most expensive (average of $261). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to BUF?

A simple way to save on the total cost of your ticket is to fly from Missouri to Buffalo in the evening. If you’re flexible enough to do this you can expect to save up to 50% on your trip compared to booking a flight at noon.

Related info for your journey

What airport do you fly into for flights to Buffalo from Missouri?
Most people fly into Buffalo (BUF) if they book a flight to Buffalo from Missouri. Buffalo is conveniently located just 8.3 mi from Buffalo’s city center.
How long is the flight from Missouri to Buffalo?
Airlines like Frontier, American Airlines, and Delta fly from Missouri to Buffalo in about 5h 28m. The time it takes to get you to your destination can typically vary by up to 50m. The distance from Missouri to Buffalo is about 867 mi. This flight may include one or multiple stops.
What are the cheapest airlines to fly from Missouri to Buffalo one-way?
One-way options have recently been found by users for as low as $95 on American Airlines. Other airlines that offer cheap prices include United Airlines from $109 and Southwest from $118 one-way.
What are the most popular routes from Missouri to Buffalo?
While some choose either Kansas City - Buffalo or Springfield-Branson - Buffalo, Lambert-St Louis - Buffalo is the most popular route from Missouri to Buffalo.
Can I find deals for flights from Missouri to Buffalo that include hotel bookings?
Yes. In addition to deals on Missouri to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Missouri to Buffalo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Buffalo.
Can I find deals for business class flights from Missouri to Buffalo?
Yes. Cheapflights offers flight deals from Missouri to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Missouri to Buffalo?
Currently, March is the cheapest month in which you can book a flight from Missouri to Buffalo (average of $136). Flying from Missouri to Buffalo in October is currently the most expensive (average of $261). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Amherst

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Top 4 airlines flying from Missouri to Buffalo

Airline	Cheapest	Average	Flexibility	On-time
United Airlines	Cheapest$167	Average$434	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$221	Average$394	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$236	Average$338	FlexibilityNo cancel fee	On-timeN/A
Southwest	Cheapest$296	Average$409	FlexibilityNo cancel fee	On-time63%

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$90+ Cheap flights from Missouri to Buffalo (BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/7. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheap flight deals from Missouri to Buffalo

Cheapest flights from Missouri to BuffaloExplore the most affordable flight options available from Missouri to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Explore the most affordable flight options available from Missouri to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

Find flight deals from Missouri to Buffalo

Keep the following information in mind while searching for Missouri to Buffalo flight deals. Data was last updated December 18, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to Buffalo that are best for you.

Best time to book a flight from Missouri to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Missouri with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Buffalo

What is the cheapest month to book a flight from Missouri to Buffalo?

What is the cheapest time of day to fly from MO to BUF?

Find hourly flight availability from Missouri to Buffalo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Buffalo from Missouri?

How long is the flight from Missouri to Buffalo?

What are the cheapest airlines to fly from Missouri to Buffalo one-way?

What are the most popular routes from Missouri to Buffalo?

Can I find deals for flights from Missouri to Buffalo that include hotel bookings?

How can I find direct flights from Missouri to Buffalo?

Can I find deals for business class flights from Missouri to Buffalo?

What is the cheapest month to book a flight from Missouri to Buffalo?

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Alternative routes for Missouri to Buffalo

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Top 4 airlines flying from Missouri to Buffalo

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Cheapest flights from Missouri to Buffalo
Explore the most affordable flight options available from Missouri to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.