How long is the flight from Missouri to Buffalo?

Airlines like Delta, American Airlines, and United Airlines fly from Missouri to Buffalo in about 3h 41m. The time it takes to get you to your destination can typically vary by up to 5h 44m. The distance from Missouri to Buffalo is about 672 mi. This flight may include one or multiple stops.

What are the cheapest airlines to fly from Missouri to Buffalo one-way?

One-way options have recently been found by users for as low as $129 on Delta. Other airlines that offer cheap prices include United Airlines from $129 and Frontier from $130 one-way.

In terms of precipitation, rainfall in Buffalo ranges from 2.5 - 4.0 inches per month. November is typically the wettest month, when rainfall can reach 4.0 in. February is typically the driest time to visit Buffalo when rainfall is around 2.5 in.

If weather is an important factor for your trip to Buffalo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 24.8 F).

What are the most popular routes from Missouri to Buffalo?

While some choose either Lambert-St Louis - Buffalo or Springfield-Branson - Buffalo, Kansas City - Buffalo is the most popular route from Missouri to Buffalo.

What are the most popular airlines that fly from Missouri to Buffalo?

The most popular airlines flying from Missouri to Buffalo are American Airlines, Delta and United Airlines. Something to consider prior to booking your flight.

What airport do you fly into for flights to Buffalo from Missouri?

Most people fly into Buffalo (BUF) if they book a flight to Buffalo from Missouri. Buffalo is conveniently located just 8.3 mi from Buffalo’s city center.

Can I find deals for flights from Missouri to Buffalo that include hotel bookings?

Yes. In addition to deals on Missouri to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Missouri to Buffalo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Buffalo.

Can I find deals for business class flights from Missouri to Buffalo?

Yes. Cheapflights offers flight deals from Missouri to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$120+ Flights from Missouri to Buffalo

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Cheap flight deals from Missouri to Buffalo

Round-trip from	$224 (Frontier)
One-way from	$120 (Flightnetwork)
Popular in	November
Cheapest in	January
Average price	$356

From Missouri to Buffalo

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One-way flight from Missouri to Buffalo

Search Deals

Highest demand for flights based on searches. 12% potential increase in price ($54 potential increase over avg. RT price).

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Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).

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Average for round-trip flights in September 2025

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Find flight deals from Missouri to Buffalo

Cheapest flights from Missouri to Buffalo
Explore the most affordable flight options available from Missouri to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

Sat 10/257:02 pmMCI - BUF

2 stops15h 17mFrontier

Sat 11/17:12 pmBUF - MCI

2 stops17h 05mFrontier

Deal found 9/13

$224

Sat 11/14:05 pmSGF - BUF

1 stop6h 30mAmerican Airlines

Wed 11/56:12 amBUF - SGF

1 stop6h 24mAmerican Airlines

Deal found 9/15

$249

Sat 11/86:00 amSGF - BUF

2 stops9h 25mDelta

Tue 11/116:00 amBUF - SGF

1 stop5h 53mDelta

Deal found 9/14

$254

Sat 10/255:22 pmSTL - BUF

1 stop4h 30mDelta

Wed 10/2911:15 amBUF - STL

1 stop6h 28mDelta

Deal found 9/14

$257

Sat 10/1112:25 pmSTL - BUF

2 stops9h 17mUnited Airlines

Sat 10/188:20 amBUF - STL

1 stop7h 07mUnited Airlines

Deal found 9/13

$262

Wed 10/17:45 amSGF - BUF

2 stops9h 47mUnited Airlines

Sat 10/48:20 amBUF - SGF

1 stop7h 16mUnited Airlines

Deal found 9/15

$264

Thu 11/136:45 pmSTL - BUF

1 stop4h 23mAmerican Airlines

Tue 11/186:00 amBUF - STL

1 stop6h 03mAmerican Airlines

Deal found 9/14

$277

Sat 12/64:49 pmSTL - BUF

1 stop5h 50mAmerican Airlines

Mon 12/85:05 amBUF - STL

1 stop6h 12mAmerican Airlines

Deal found 9/15

$278

Fri 10/1011:32 amSTL - BUF

1 stop23h 04mFrontier

Thu 10/167:14 pmBUF - STL

2 stops14h 53mFrontier

Deal found 9/13

$286

Fri 10/318:28 pmMCI - BUF

2 stops12h 40mFrontier

Fri 11/79:53 pmBUF - MCI

2 stops22h 40mFrontier

Deal found 9/16

$287

Thu 10/27:55 pmSTL - BUF

2 stops14h 27mFrontier

Sun 10/57:41 pmBUF - STL

2 stops20h 23mFrontier

Deal found 9/15

$290

Fri 10/1011:32 amSTL - BUF

2 stops32h 17mFrontier

Mon 10/205:24 pmBUF - STL

1 stop16h 43mFrontier

Deal found 9/13

$292

Best flights from Missouri to Buffalo
Discover carefully curated flight deals from Missouri to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 16, 2025.

Sat 11/86:00 amSGF - BUF

2 stops9h 25mDelta

Tue 11/116:00 amBUF - SGF

1 stop5h 53mDelta

Deal found 9/14

$254

Sat 10/256:00 amSTL - BUF

1 stop3h 41mAmerican Airlines

Wed 10/296:44 pmBUF - STL

1 stop5h 21mAmerican Airlines

Deal found 9/16

$257

Sat 10/1112:25 pmSTL - BUF

2 stops9h 17mUnited Airlines

Sat 10/188:20 amBUF - STL

1 stop7h 07mUnited Airlines

Deal found 9/13

$262

Fri 10/1011:32 amSTL - BUF

1 stop23h 04mFrontier

Sun 10/196:48 pmBUF - STL

2 stops39h 19mFrontier

Deal found 9/13

$292

Thu 10/210:35 amSTL - BUF

2 stops23h 47mMultiple Airlines

Sun 10/54:57 pmBUF - STL

1 stop17h 09mMultiple Airlines

Deal found 9/15

$310

Sat 10/251:15 pmMCI - BUF

1 stop8h 35mSouthwest

Sat 11/16:40 amBUF - MCI

1 stop6h 00mSouthwest

Deal found 9/13

$313

Wed 10/17:45 amSGF - BUF

2 stops9h 47mUnited Airlines

Sat 10/48:20 amBUF - SGF

1 stop7h 16mUnited Airlines

Deal found 9/15

$264

Wed 2/189:05 amSGF - BUF

1 stop6h 25mAmerican Airlines

Sat 2/214:57 pmBUF - SGF

1 stop4h 25mAmerican Airlines

Deal found 9/14

$269

Sat 2/286:45 amSTL - BUF

1 stop4h 06mDelta

Mon 3/26:50 pmBUF - STL

1 stop5h 50mDelta

Deal found 9/15

$277

Tue 9/307:45 amSGF - BUF

2 stops9h 47mUnited Airlines

Sat 10/48:20 amBUF - SGF

1 stop7h 16mUnited Airlines

Deal found 9/15

$264

Sat 12/64:49 pmSTL - BUF

1 stop5h 50mAmerican Airlines

Mon 12/85:05 amBUF - STL

1 stop6h 12mAmerican Airlines

Deal found 9/15

$278

Sat 10/257:02 pmMCI - BUF

2 stops15h 17mFrontier

Sat 11/110:53 amBUF - MCI

1 stop6h 41mFrontier

Deal found 9/13

$306

Sat 11/13:23 pmSGF - BUF

1 stop7h 16mDelta

Wed 11/56:03 amBUF - SGF

2 stops9h 47mDelta

Deal found 9/15

$304

Wed 10/227:02 pmMCI - BUF

2 stops15h 17mFrontier

Sat 10/259:45 pmBUF - MCI

2 stops13h 57mFrontier

Deal found 9/14

$309

Tue 10/74:07 pmMCI - BUF

1 stop5h 35mUnited Airlines

Wed 10/810:28 amBUF - MCI

1 stop5h 20mUnited Airlines

Deal found 9/16

$292

Wed 10/12:23 pmSGF - BUF

1 stop7h 45mAmerican Airlines

Sat 10/45:33 pmBUF - SGF

1 stop4h 31mAmerican Airlines

Deal found 9/15

$299

Sat 2/286:00 amSGF - BUF

1 stop6h 02mDelta

Tue 3/36:00 amBUF - SGF

1 stop6h 14mDelta

Deal found 9/13

$304

Tue 10/710:40 amMCI - BUF

2 stops8h 50mSouthwest

Wed 10/86:00 amBUF - MCI

2 stops6h 25mSouthwest

Deal found 9/16

$382

Sun 10/126:05 pmSTL - BUF

1 stop25h 13mFrontier

Thu 10/167:14 pmBUF - STL

2 stops14h 53mFrontier

Deal found 9/13

$319

Thu 12/253:14 pmSGF - BUF

1 stop5h 03mUnited Airlines

Tue 1/68:30 amBUF - SGF

1 stop7h 08mUnited Airlines

Deal found 9/15

$294

Thu 9/255:15 amMCI - BUF

1 stop11h 12mMultiple Airlines

Fri 10/36:59 pmBUF - MCI

1 stop29h 08mMultiple Airlines

Deal found 9/14

$405

Wed 10/2211:11 amMCI - BUF

1 stop4h 52mAmerican Airlines

Sat 10/255:27 pmBUF - MCI

1 stop4h 44mAmerican Airlines

Deal found 9/14

$305

Sun 10/129:10 amSTL - BUF

1 stop5h 18mDelta

Sat 10/186:20 amBUF - STL

1 stop4h 17mDelta

Deal found 9/13

$322

Sat 11/13:09 pmMCI - BUF

1 stop6h 34mAmerican Airlines

Tue 11/45:25 pmBUF - MCI

1 stop6h 40mAmerican Airlines

Deal found 9/14

$305

Sat 11/11:47 pmMCI - BUF

1 stop8h 05mUnited Airlines

Tue 11/46:00 amBUF - MCI

2 stops9h 21mUnited Airlines

Deal found 9/14

$310

Wed 10/2211:40 amMCI - BUF

2 stops8h 33mUnited Airlines

Sat 10/258:25 amBUF - MCI

1 stop8h 51mUnited Airlines

Deal found 9/14

$320

Sun 10/125:00 amSTL - BUF

1 stop3h 53mUnited Airlines

Tue 10/147:07 amBUF - STL

1 stop4h 42mUnited Airlines

Deal found 9/13

$322

Sat 10/2512:25 pmSTL - BUF

2 stops9h 13mUnited Airlines

Wed 10/296:00 amBUF - STL

1 stop6h 04mUnited Airlines

Deal found 9/16

$332

Mon 10/61:00 pmMCI - BUF

1 stop7h 13mUnited Airlines

Wed 10/86:30 amBUF - MCI

2 stops9h 18mUnited Airlines

Deal found 9/16

$377

Mon 9/292:52 pmCOU - BUF

1 stop17h 56mUnited Airlines

Fri 10/37:45 pmBUF - COU

2 stops19h 32mUnited Airlines

Deal found 9/14

$633

Last-minute flights from Missouri to Buffalo
Discover last-minute flight deals from Missouri to Buffalo. Data last updated September 16, 2025 and is based on user searches.

Wed 10/17:45 amSGF - BUF

2 stops9h 47mUnited Airlines

Sat 10/48:20 amBUF - SGF

1 stop7h 16mUnited Airlines

Deal found 9/15

$264

Wed 10/12:23 pmSGF - BUF

1 stop7h 45mAmerican Airlines

Sat 10/45:33 pmBUF - SGF

1 stop4h 31mAmerican Airlines

Deal found 9/15

$299

Thu 10/27:55 pmSTL - BUF

2 stops14h 27mFrontier

Sun 10/57:41 pmBUF - STL

2 stops20h 23mFrontier

Deal found 9/15

$290

Tue 10/74:07 pmMCI - BUF

1 stop5h 35mUnited Airlines

Wed 10/810:28 amBUF - MCI

1 stop5h 20mUnited Airlines

Deal found 9/16

$292

Fri 10/1011:32 amSTL - BUF

1 stop23h 04mFrontier

Thu 10/167:14 pmBUF - STL

2 stops14h 53mFrontier

Deal found 9/13

$286

Fri 10/1011:32 amSTL - BUF

2 stops32h 17mFrontier

Mon 10/205:24 pmBUF - STL

1 stop16h 43mFrontier

Deal found 9/13

$292

Fri 10/1011:32 amSTL - BUF

1 stop23h 04mFrontier

Sat 10/181:02 pmBUF - STL

2 stops21h 20mFrontier

Deal found 9/13

$305

Sat 10/1112:25 pmSTL - BUF

2 stops9h 17mUnited Airlines

Sat 10/188:20 amBUF - STL

1 stop7h 07mUnited Airlines

Deal found 9/13

$262

Sat 10/115:25 pmSTL - BUF

1 stop5h 14mDelta

Thu 10/166:20 amBUF - STL

1 stop4h 17mDelta

Deal found 9/13

$277

Sat 10/257:02 pmMCI - BUF

2 stops15h 17mFrontier

Sat 11/17:12 pmBUF - MCI

2 stops17h 05mFrontier

Deal found 9/13

$224

Sat 10/255:22 pmSTL - BUF

1 stop4h 30mDelta

Wed 10/2911:15 amBUF - STL

1 stop6h 28mDelta

Deal found 9/14

$257

Fri 10/318:28 pmMCI - BUF

2 stops12h 40mFrontier

Fri 11/79:53 pmBUF - MCI

2 stops22h 40mFrontier

Deal found 9/16

$287

One-way flights from Missouri to Buffalo
Search for one-way flight options from Missouri to Buffalo. Find affordable one-way fares based on user searches. Data last updated September 16, 2025.

Sat 11/155:19 pmMCI - BUF

1 stop17h 35mFrontier

Deal found 9/16

$120

Wed 10/83:23 pmSTL - BUF

1 stop4h 50mUnited Airlines

Deal found 9/14

$129

Fri 10/1011:37 amMCI - BUF

2 stops32h 12mFrontier

Deal found 9/14

$130

Sun 10/1211:37 amMCI - BUF

2 stops31h 41mFrontier

Deal found 9/14

$131

Wed 10/88:15 amSTL - BUF

2 stops7h 10mSouthwest

Deal found 9/14

$134

Fri 10/1011:32 amSTL - BUF

2 stops32h 17mFrontier

Deal found 9/14

$136

Mon 10/135:15 amMCI - BUF

1 stop14h 03mMultiple Airlines

Deal found 9/14

$136

Sat 10/45:15 amMCI - BUF

1 stop11h 59mMultiple Airlines

Deal found 9/16

$139

Sat 11/157:45 pmSTL - BUF

2 stops23h 24mFrontier

Deal found 9/14

$148

Fri 12/1211:51 amMCI - BUF

1 stop5h 13mFrontier

Deal found 9/14

$148

Thu 11/136:45 pmSTL - BUF

1 stop4h 23mAmerican Airlines

Deal found 9/14

$149

Wed 11/125:47 pmMCI - BUF

1 stop4h 10mDelta

Deal found 9/16

$149

Fly from

Fly to

Route

Depart

Return

Price

SpringfieldBuffalo

SGF - BUF

SGFBUF

Springfield-Branson

Sat 11/8

6:00 am-4:25 pm

2 stops9h 25m

Buffalo

Tue 11/11

6:00 am-10:53 am

1 stop5h 53m

$254

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Sat 10/25

6:00 am-10:41 am

1 stop3h 41m

Buffalo

Wed 10/29

6:44 pm-11:05 pm

1 stop5h 21m

$257

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Sat 10/11

12:25 pm-10:42 pm

2 stops9h 17m

Buffalo

Sat 10/18

8:20 am-2:27 pm

1 stop7h 07m

$262

SpringfieldBuffalo

SGF - BUF

SGFBUF

Springfield-Branson

Wed 10/1

7:45 am-6:32 pm

2 stops9h 47m

Buffalo

Sat 10/4

8:20 am-2:36 pm

1 stop7h 16m

$264

SpringfieldBuffalo

SGF - BUF

SGFBUF

Springfield-Branson

Tue 9/30

7:45 am-6:32 pm

2 stops9h 47m

Buffalo

Sat 10/4

8:20 am-2:36 pm

1 stop7h 16m

$264

SpringfieldBuffalo

SGF - BUF

SGFBUF

Springfield-Branson

Wed 2/18

9:05 am-4:30 pm

1 stop6h 25m

Buffalo

Sat 2/21

4:57 pm-8:22 pm

1 stop4h 25m

$269

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Sat 2/28

6:45 am-11:51 am

1 stop4h 06m

Buffalo

Mon 3/2

6:50 pm-11:40 pm

1 stop5h 50m

$277

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Sat 12/6

4:49 pm-11:39 pm

1 stop5h 50m

Buffalo

Mon 12/8

5:05 am-10:17 am

1 stop6h 12m

$278

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Fri 10/10

11:32 am-11:36 am

1 stop23h 04m

Buffalo

Sun 10/19

6:48 pm-9:07 am

2 stops39h 19m

$292

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

Tue 10/7

4:07 pm-10:42 pm

1 stop5h 35m

Buffalo

Wed 10/8

10:28 am-2:48 pm

1 stop5h 20m

$292

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 46 results

...

Best time to book a flight from Missouri to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Missouri with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Buffalo

What is the cheapest month to book a flight from Missouri to Buffalo?

Currently, January is the cheapest month in which you can book a flight from Missouri to Buffalo (average of $256). Flying from Missouri to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to BUF?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Buffalo as you normally would.

Related info for your journey

What airport do you fly into for flights to Buffalo from Missouri?
Most people fly into Buffalo (BUF) if they book a flight to Buffalo from Missouri. Buffalo is conveniently located just 8.3 mi from Buffalo’s city center.
How long is the flight from Missouri to Buffalo?
Airlines like Delta, American Airlines, and United Airlines fly from Missouri to Buffalo in about 3h 41m. The time it takes to get you to your destination can typically vary by up to 5h 44m. The distance from Missouri to Buffalo is about 672 mi. This flight may include one or multiple stops.
What are the cheapest airlines to fly from Missouri to Buffalo one-way?
One-way options have recently been found by users for as low as $129 on Delta. Other airlines that offer cheap prices include United Airlines from $129 and Frontier from $130 one-way.
What are the most popular routes from Missouri to Buffalo?
While some choose either Lambert-St Louis - Buffalo or Springfield-Branson - Buffalo, Kansas City - Buffalo is the most popular route from Missouri to Buffalo.
Can I find deals for flights from Missouri to Buffalo that include hotel bookings?
Yes. In addition to deals on Missouri to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Missouri to Buffalo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Buffalo.
Can I find deals for business class flights from Missouri to Buffalo?
Yes. Cheapflights offers flight deals from Missouri to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Missouri to Buffalo?
Currently, January is the cheapest month in which you can book a flight from Missouri to Buffalo (average of $256). Flying from Missouri to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Orchard Park

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Eden

Amherst

West Seneca

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Top 4 airlines flying from Missouri to Buffalo

Airline	Cheapest	Average	Flexibility	On-time
United Airlines	Cheapest$167	Average$454	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$208	Average$403	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$238	Average$354	FlexibilityNo cancel fee	On-timeN/A
Southwest	Cheapest$301	Average$406	FlexibilityNo cancel fee	On-time63%

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$120+ Cheap flights from Missouri to Buffalo (BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/15. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheap flight deals from Missouri to Buffalo

Keep the following information in mind while searching for Missouri to Buffalo flight deals. Data was last updated September 16, 2025.

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Missouri to Buffalo

Cheapest flights from Missouri to BuffaloExplore the most affordable flight options available from Missouri to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

Explore the most affordable flight options available from Missouri to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to Buffalo that are best for you.

Best time to book a flight from Missouri to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Missouri with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Buffalo

What is the cheapest month to book a flight from Missouri to Buffalo?

What is the cheapest time of day to fly from MO to BUF?

Find hourly flight availability from Missouri to Buffalo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Buffalo from Missouri?

How long is the flight from Missouri to Buffalo?

What are the cheapest airlines to fly from Missouri to Buffalo one-way?

What are the most popular routes from Missouri to Buffalo?

Can I find deals for flights from Missouri to Buffalo that include hotel bookings?

How can I find direct flights from Missouri to Buffalo?

Can I find deals for business class flights from Missouri to Buffalo?

What is the cheapest month to book a flight from Missouri to Buffalo?

Traveling to a place near Buffalo?

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Alternative routes for Missouri to Buffalo

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Missouri to Buffalo

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Cheapest flights from Missouri to Buffalo
Explore the most affordable flight options available from Missouri to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.