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$119+ Cheap flights from Missouri to Buffalo (BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/30. Fares are subject to change and may not be available on all flights or dates of travel.
STL — BUF
jun. 17 — jun. 241
mar. 6/17
mar. 6/24
1 adult, Economy
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Cheap flight deals from Missouri to Buffalo

Keep the following information in mind while searching for Missouri to Buffalo flight deals. Data was last updated junio 12, 2025.

Round-trip from

$213
(American Airlines)

One-way from

$119
(Delta)

Popular in

November

Cheapest in

January

Average price

$456
From Missouri to Buffalo
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One-way flight from Missouri to Buffalo
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Highest demand for flights based on searches. 6% potential increase in price ($26 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Missouri to Buffalo

Cheapest flights from Missouri to Buffalo
Explore the most affordable flight options available from Missouri to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/247:23 amSTL - BUF
1 stop8h 27mAmerican Airlines
mié. 10/111:54 amBUF - STL
1 stop10h 59mAmerican Airlines
Deal found 6/12$213
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 6/3011:17 amSTL - BUF
1 stop6h 27mDelta
vie. 7/411:12 amBUF - STL
1 stop7h 53mDelta
Deal found 6/11$237
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/126:16 amMCI - BUF
1 stop4h 48mAmerican Airlines
mar. 8/2611:34 amBUF - MCI
1 stop10h 14mAmerican Airlines
Deal found 6/11$248
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/246:25 amSTL - BUF
2 stops7h 45mSouthwest
mié. 10/18:25 amBUF - STL
1 stop6h 45mSouthwest
Deal found 6/11$256
This Southwest deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/127:00 amMCI - BUF
1 stop4h 30mSouthwest
mar. 8/264:05 pmBUF - MCI
2 stops7h 20mSouthwest
Deal found 6/10$276
This American Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 7/15:30 pmSGF - BUF
1 stop5h 18mAmerican Airlines
vie. 7/410:50 amBUF - SGF
1 stop7h 31mAmerican Airlines
Deal found 6/12$279
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 7/95:00 amSTL - BUF
1 stop3h 54mUnited Airlines
sáb. 7/126:00 amBUF - STL
1 stop5h 42mUnited Airlines
Deal found 6/9$307
This Delta deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/152:03 pmMCI - BUF
1 stop3h 51mDelta
sáb. 8/2312:18 pmBUF - MCI
1 stop5h 34mDelta
Deal found 6/11$313
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 8/53:28 pmMCI - BUF
2 stops7h 16mUnited Airlines
sáb. 8/96:45 amBUF - MCI
1 stop4h 44mUnited Airlines
Deal found 6/10$335
This FlightHub deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 8/282:18 pmMCI - BUF
1 stop24h 42mFrontier
dom. 8/312:22 pmBUF - MCI
1 stop24h 11mFrontier
Deal found 6/11$360
This Frontier deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/152:27 pmSTL - BUF
2 stops20h 44mFrontier
jue. 8/2111:12 amBUF - STL
2 stops22h 59mFrontier
Deal found 6/10$380
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 6/275:45 amSGF - BUF
2 stops10h 10mUnited Airlines
mar. 7/17:00 amBUF - SGF
1 stop4h 48mUnited Airlines
Deal found 6/12$455

Cheapflights Fare Finder

Customize your flight search to find flights from Missouri to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
Use the filters below to find and compare flights from Missouri to Buffalo that are best for you.

Fly from

Missouri

Fly to

Buffalo

Route

Depart

Return

Price

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

mié. 9/24

7:23 am-4:50 pm

1 stop8h 27m

Buffalo

mié. 10/1

11:54 am-9:53 pm

1 stop10h 59m

$213

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

lun. 6/30

11:17 am-6:44 pm

1 stop6h 27m

Buffalo

vie. 7/4

11:12 am-6:05 pm

1 stop7h 53m

$237

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

mar. 8/12

6:16 am-12:04 pm

1 stop4h 48m

Buffalo

mar. 8/26

11:34 am-8:48 pm

1 stop10h 14m

$248

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

mié. 9/24

6:25 am-3:10 pm

2 stops7h 45m

Buffalo

mié. 10/1

8:25 am-2:10 pm

1 stop6h 45m

$256

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

mar. 8/12

7:00 am-12:30 pm

1 stop4h 30m

Buffalo

mar. 8/26

4:05 pm-10:25 pm

2 stops7h 20m

$276

SpringfieldBuffalo

SGF - BUF

SGFBUF

Springfield-Branson

mar. 7/1

5:30 pm-11:48 pm

1 stop5h 18m

Buffalo

vie. 7/4

10:50 am-5:21 pm

1 stop7h 31m

$279

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

mié. 7/9

5:00 am-9:54 am

1 stop3h 54m

Buffalo

sáb. 7/12

6:00 am-10:42 am

1 stop5h 42m

$307

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

vie. 8/15

2:03 pm-6:54 pm

1 stop3h 51m

Buffalo

sáb. 8/23

12:18 pm-4:52 pm

1 stop5h 34m

$313

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

mar. 8/5

3:28 pm-11:44 pm

2 stops7h 16m

Buffalo

sáb. 8/9

6:45 am-10:29 am

1 stop4h 44m

$335

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

jue. 8/28

2:18 pm-4:00 pm

1 stop24h 42m

Buffalo

dom. 8/31

2:22 pm-1:33 pm

1 stop24h 11m

$360

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Showing 1-10 of 29 results
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Best time to book a flight from Missouri to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Buffalo

What is the cheapest month to book a flight from Missouri to Buffalo?

Currently, January is the cheapest month in which you can book a flight from Missouri to Buffalo (average of $256). Flying from Missouri to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to BUF?

Find hourly flight availability from Missouri to Buffalo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated junio 12, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Buffalo as you normally would.

Rainfall in Buffalo by month

Plan your trip to Buffalo by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Buffalo ranges from 2.5 - 4.0 inches per month. November is typically the wettest month, when rainfall can reach 4.0 in. February is typically the driest time to visit Buffalo when rainfall is around 2.5 in.

Temperature in Buffalo by month

Plan your trip to Buffalo by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Buffalo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 24.8 F).

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated junio 12, 2025.
Read through reviews of airlines operating flights from Missouri to Buffalo, such as Southwest, Delta and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,287 reviews

Boarding

8.2

Comfort

8.0

Food

7.1

Overall

8.0

Entertainment

7.6

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Southwest
8.0
Very good
4,287 reviews
Southwest
8.0
Very good
4,287 reviews

Boarding

8.2

Comfort

8.0

Food

7.1

Overall

8.0

Entertainment

7.6

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Delta
8.0
Very good
7,950 reviews
Southwest
8.0
Very good
4,287 reviews

Boarding

8.2

Comfort

8.0

Food

7.1

Overall

8.0

Entertainment

7.6

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
United Airlines
7.4
Good
8,790 reviews
Southwest
8.0
Very good
4,287 reviews

Boarding

8.2

Comfort

8.0

Food

7.1

Overall

8.0

Entertainment

7.6

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,287 reviews

Boarding

8.2

Comfort

8.0

Food

7.1

Overall

8.0

Entertainment

7.6

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Frontier
5.9
Fair
3,295 reviews
Southwest
8.0
Very good
4,287 reviews

Boarding

8.2

Comfort

8.0

Food

7.1

Overall

8.0

Entertainment

7.6

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Buffalo from Missouri?

    Most people fly into Buffalo (BUF) if they book a flight to Buffalo from Missouri. Buffalo is conveniently located just 8.3 mi from Buffalo’s city center.

  • What are the cheapest airlines to fly from Missouri to Buffalo one-way?

    One-way options have recently been found by users for as low as $119 on Delta. Other airlines that offer cheap prices include American Airlines from $126 and Frontier from $144 one-way.

  • What are the most popular routes from Missouri to Buffalo?

    While some choose either Kansas City - Buffalo or Columbia Regional - Buffalo, Lambert-St Louis - Buffalo is the most popular route from Missouri to Buffalo.

  • Can I find deals for flights from Missouri to Buffalo that include hotel bookings?

    Yes. In addition to deals on Missouri to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Buffalo.

  • Can I find deals for business class flights from Missouri to Buffalo?

    Yes. Cheapflights offers flight deals from Missouri to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Buffalo?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Buffalo (average of $256). Flying from Missouri to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Missouri?

Book flights to Missouri if you plan to visit one of these locations
Williamsville
Amherst
Orchard Park
Batavia
Eden
Cheektowaga
West Seneca

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See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Missouri to Buffalo

Discover the top 4 airlines that operate flights from Missouri to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated junio 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$179Average$426FlexibilityNo cancel feeOn-time69%
DeltaCheapest$200Average$359FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$228Average$428FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$306Average$406FlexibilityNo cancel feeOn-time63%

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