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$117+ Cheap flights from Missouri to Buffalo (BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/13. Fares are subject to change and may not be available on all flights or dates of travel.
STL — BUF
Aug 4 — Aug 111
Mon 8/4
Mon 8/11
1 adult, Economy
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Cheap flight deals from Missouri to Buffalo

Keep the following information in mind while searching for Missouri to Buffalo flight deals. Data was last updated July 30, 2025.

Round-trip from

$215
(FlightHub)

One-way from

$117
(FlightHub)

Popular in

November

Cheapest in

January

Average price

$396
From Missouri to Buffalo
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One-way flight from Missouri to Buffalo
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($38 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Missouri to Buffalo

Cheapest flights from Missouri to Buffalo
Explore the most affordable flight options available from Missouri to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.

This FlightHub deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/65:11 pmSTL - BUF
1 stop14h 39mFrontier
Mon 12/85:06 pmBUF - STL
1 stop6h 40mFrontier
Deal found 7/29$215
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/139:00 amSTL - BUF
1 stop7h 33mDelta
Sun 11/166:00 amBUF - STL
1 stop5h 40mDelta
Deal found 7/29$237
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1111:50 amMCI - BUF
1 stop5h 58mAmerican Airlines
Wed 10/155:27 pmBUF - MCI
1 stop4h 25mAmerican Airlines
Deal found 7/29$237
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/101:35 pmSTL - BUF
2 stops7h 35mSouthwest
Fri 9/126:10 amBUF - STL
1 stop3h 30mSouthwest
Deal found 7/30$242
This FlightHub deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/183:01 pmMCI - BUF
1 stop24h 01mFrontier
Sun 9/214:57 pmBUF - MCI
1 stop21h 51mFrontier
Deal found 7/30$245
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/36:15 amMCI - BUF
2 stops7h 55mSouthwest
Wed 9/105:50 amBUF - MCI
2 stops6h 40mSouthwest
Deal found 7/29$247
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/265:30 pmSGF - BUF
1 stop5h 27mDelta
Sat 9/66:00 amBUF - SGF
1 stop5h 56mDelta
Deal found 7/30$249
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/286:02 amSTL - BUF
1 stop4h 24mAmerican Airlines
Mon 9/15:29 amBUF - STL
1 stop5h 11mAmerican Airlines
Deal found 7/29$259
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2612:05 pmSGF - BUF
2 stops8h 35mAmerican Airlines
Sat 9/61:10 pmBUF - SGF
2 stops8h 18mAmerican Airlines
Deal found 7/30$259
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/246:37 amMCI - BUF
1 stop4h 31mDelta
Sun 9/286:15 amBUF - MCI
1 stop4h 33mDelta
Deal found 7/28$302
This United Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/266:00 amSGF - BUF
2 stops9h 52mUnited Airlines
Wed 8/275:54 pmBUF - SGF
1 stop5h 21mUnited Airlines
Deal found 7/30$326
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/111:00 pmMCI - BUF
2 stops8h 42mUnited Airlines
Thu 10/165:55 pmBUF - MCI
1 stop4h 50mUnited Airlines
Deal found 7/29$352

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
Use the filters below to find and compare flights from Missouri to Buffalo that are best for you.

Fly from

Missouri

Fly to

Buffalo

Route

Depart

Return

Price

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Sat 12/6

5:11 pm-8:50 am

1 stop14h 39m

Buffalo

Mon 12/8

5:06 pm-10:46 pm

1 stop6h 40m

$215

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Thu 11/13

9:00 am-5:33 pm

1 stop7h 33m

Buffalo

Sun 11/16

6:00 am-10:40 am

1 stop5h 40m

$237

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

Sat 10/11

11:50 am-6:48 pm

1 stop5h 58m

Buffalo

Wed 10/15

5:27 pm-8:52 pm

1 stop4h 25m

$237

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Wed 9/10

1:35 pm-10:10 pm

2 stops7h 35m

Buffalo

Fri 9/12

6:10 am-8:40 am

1 stop3h 30m

$242

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

Thu 9/18

3:01 pm-4:02 pm

1 stop24h 01m

Buffalo

Sun 9/21

4:57 pm-1:48 pm

1 stop21h 51m

$245

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

Wed 9/3

6:15 am-3:10 pm

2 stops7h 55m

Buffalo

Wed 9/10

5:50 am-11:30 am

2 stops6h 40m

$247

SpringfieldBuffalo

SGF - BUF

SGFBUF

Springfield-Branson

Tue 8/26

5:30 pm-11:57 pm

1 stop5h 27m

Buffalo

Sat 9/6

6:00 am-10:56 am

1 stop5h 56m

$249

St. LouisBuffalo

STL - BUF

STLBUF

Lambert-St Louis

Thu 8/28

6:02 am-11:26 am

1 stop4h 24m

Buffalo

Mon 9/1

5:29 am-9:40 am

1 stop5h 11m

$259

SpringfieldBuffalo

SGF - BUF

SGFBUF

Springfield-Branson

Tue 8/26

12:05 pm-9:40 pm

2 stops8h 35m

Buffalo

Sat 9/6

1:10 pm-8:28 pm

2 stops8h 18m

$259

Kansas CityBuffalo

MCI - BUF

MCIBUF

Kansas City

Wed 9/24

6:37 am-12:08 pm

1 stop4h 31m

Buffalo

Sun 9/28

6:15 am-9:48 am

1 stop4h 33m

$302

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/30

Showing 1-10 of 27 results
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2
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Best time to book a flight from Missouri to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Buffalo

What is the cheapest month to book a flight from Missouri to Buffalo?

Currently, January is the cheapest month in which you can book a flight from Missouri to Buffalo (average of $256). Flying from Missouri to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to BUF?

Find hourly flight availability from Missouri to Buffalo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 30, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Buffalo as you normally would.

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated July 30, 2025.
Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Missouri to Buffalo. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,241 reviews

Boarding

8.1

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Southwest
8.0
Very good
4,241 reviews
Southwest
8.0
Very good
4,241 reviews

Boarding

8.1

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Delta
8.0
Very good
7,980 reviews
Southwest
8.0
Very good
4,241 reviews

Boarding

8.1

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
United Airlines
7.4
Good
8,896 reviews
Southwest
8.0
Very good
4,241 reviews

Boarding

8.1

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,241 reviews

Boarding

8.1

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Frontier
5.9
Fair
3,237 reviews
Southwest
8.0
Very good
4,241 reviews

Boarding

8.1

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Buffalo from Missouri?

    Most people fly into Buffalo (BUF) if they book a flight to Buffalo from Missouri. Buffalo is conveniently located just 8.3 mi from Buffalo’s city center.

  • What are the cheapest airlines to fly from Missouri to Buffalo one-way?

    One-way options have recently been found by users for as low as $117 on Frontier. Other airlines that offer cheap prices include Delta from $119 and Southwest from $124 one-way.

  • What are the most popular routes from Missouri to Buffalo?

    While some choose either Lambert-St Louis - Buffalo or Columbia Regional - Buffalo, Kansas City - Buffalo is the most popular route from Missouri to Buffalo.

  • Can I find deals for flights from Missouri to Buffalo that include hotel bookings?

    Yes. In addition to deals on Missouri to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Buffalo.

  • Can I find deals for business class flights from Missouri to Buffalo?

    Yes. Cheapflights offers flight deals from Missouri to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Buffalo?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Buffalo (average of $256). Flying from Missouri to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Orchard Park
Batavia
Williamsville
Eden
Amherst
West Seneca

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missouri to Buffalo

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Missouri to Buffalo

Discover the top 4 airlines that operate flights from Missouri to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$179Average$450FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$228Average$420FlexibilityNo cancel feeOn-time71%
DeltaCheapest$243Average$351FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$306Average$403FlexibilityNo cancel feeOn-time63%

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