$161+ Cheap flights from Columbia, MO to Buffalo (COU - BUF)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/7. Fares are subject to change and may not be available on all flights or dates of travel.
COU — BUF
Oct 25 — Nov 11
Round-trip
1 adult, Economy
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Find cheap flights from Columbia to Buffalo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Columbia to Buffalo
Cheapest
Best
Last-minute
One-way
Cheapest flights from Columbia to BuffaloExplore the most affordable flight options available from Columbia to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 25, 2026.
Explore the most affordable flight options available from Columbia to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 25, 2026.
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2411:19 am -
1 stop4h 24m
Wed 10/285:58 pm -
1 stop6h 00m
Deal found 9/22![United Airlines logo]()
$428
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/510:24 am -
1 stop6h 41m
Thu 11/126:45 pm -
1 stop4h 30m
Deal found 9/21![American Airlines logo]()
$429
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/166:15 am -
2 stops10h 36m
Fri 1/112:30 pm -
2 stops9h 59m
Deal found 9/22![American Airlines logo]()
$492
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/153:04 pm -
2 stops7h 30m
Fri 1/15:35 pm -
1 stop5h 17m
Deal found 9/22![United Airlines logo]()
$498
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3010:40 am -
1 stop5h 28m
Mon 11/26:46 pm -
1 stop4h 29m
Deal found 9/24![American Airlines logo]()
$528
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:25 pm -
1 stop4h 34m
Sun 11/112:05 pm -
2 stops11h 10m
Deal found 9/24![American Airlines logo]()
$534
Best flights from Columbia to BuffaloDiscover carefully curated flight deals from Columbia to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 25, 2026.
Discover carefully curated flight deals from Columbia to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 25, 2026.
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2411:19 am -
1 stop4h 24m
Wed 10/285:58 pm -
1 stop6h 00m
Deal found 9/19![United Airlines logo]()
$428
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3010:40 am -
1 stop5h 28m
Mon 11/212:10 pm -
2 stops11h 05m
Deal found 9/24![American Airlines logo]()
$434
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/510:24 am -
2 stops10h 11m
Thu 11/126:45 pm -
1 stop4h 30m
Deal found 9/21![American Airlines logo]()
$435
Last-minute flights from Columbia to BuffaloDiscover last-minute flight deals from Columbia to Buffalo. Data last updated September 25, 2026 and is based on user searches.
Discover last-minute flight deals from Columbia to Buffalo. Data last updated September 25, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:24 pm -
1 stop4h 35m
Sun 10/113:56 pm -
1 stop7h 43m
Deal found 9/22![American Airlines logo]()
$612
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:15 am -
2 stops7h 08m
Sun 10/116:00 am -
2 stops9h 38m
Deal found 9/22![United Airlines logo]()
$628
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2411:19 am -
1 stop4h 24m
Wed 10/285:58 pm -
1 stop6h 00m
Deal found 9/22![United Airlines logo]()
$428
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3010:40 am -
1 stop5h 28m
Mon 11/26:46 pm -
1 stop4h 29m
Deal found 9/24![American Airlines logo]()
$528
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:25 pm -
1 stop4h 34m
Sun 11/112:05 pm -
2 stops11h 10m
Deal found 9/24![American Airlines logo]()
$534
One-way flights from Columbia to BuffaloSearch for one-way flight options from Columbia to Buffalo. Find affordable one-way fares based on user searches. Data last updated September 25, 2026.
Search for one-way flight options from Columbia to Buffalo. Find affordable one-way fares based on user searches. Data last updated September 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:02 pm -
2 stops41h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Multiple Airlines logo]()
$161
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/510:23 am -
1 stop6h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![American Airlines logo]()
$278
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/511:25 am -
2 stops11h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![United Airlines logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/52:49 pm -
3 stops45h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$343
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:12 am -
1 stop6h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![American Airlines logo]()
$428
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/47:11 am -
1 stop6h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![American Airlines logo]()
$563
Find flight deals from Columbia to Buffalo
Discover tips and strategies to find the most affordable flight options for your journey from Columbia (COU) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $428 (United Airlines) |
One-way from | $161 (Kiwi.com) |
Popular in | July |
Cheapest in | January |
Average price | $323 |
Cheapflights Fare Finder
Customize your flight search to find flights from Columbia to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 25, 2026.
Use the filters below to find and compare flights from Columbia to Buffalo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ColumbiaBuffalo
COU Columbia Regional - BUF Buffalo
COUBUF
Columbia Regional
Mon 12/7
6:02 pm-12:20 pm
2 stops41h 18m
Buffalo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$161
ColumbiaBuffalo
COU Columbia Regional - BUF Buffalo
COUBUF
Columbia Regional
Sat 12/5
11:25 am-11:34 pm
2 stops11h 09m
Buffalo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$284
ColumbiaBuffalo
COU Columbia Regional - BUF Buffalo
COUBUF
Columbia Regional
Mon 10/5
2:49 pm-12:55 pm
3 stops45h 06m
Buffalo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$343
Quickest round-trip
ColumbiaBuffalo
COU Columbia Regional - BUF Buffalo
COUBUF
Columbia Regional
Mon 10/5
7:12 am-3:06 pm
1 stop6h 54m
Buffalo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$428
ColumbiaBuffalo
COU Columbia Regional - BUF Buffalo
COUBUF
Columbia Regional
Sat 10/24
11:19 am-4:43 pm
1 stop4h 24m
Buffalo
Wed 10/28
5:58 pm-10:58 pm
1 stop6h 00m
$428
ColumbiaBuffalo
COU Columbia Regional - BUF Buffalo
COUBUF
Columbia Regional
Fri 10/30
10:40 am-5:08 pm
1 stop5h 28m
Buffalo
Mon 11/2
12:10 pm-10:15 pm
2 stops11h 05m
$434
ColumbiaBuffalo
COU Columbia Regional - BUF Buffalo
COUBUF
Columbia Regional
Thu 11/5
10:24 am-9:35 pm
2 stops10h 11m
Buffalo
Thu 11/12
6:45 pm-10:15 pm
1 stop4h 30m
$435
ColumbiaBuffalo
COU Columbia Regional - BUF Buffalo
COUBUF
Columbia Regional
Sun 10/4
5:44 am-2:52 pm
2 stops8h 08m
Buffalo
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$569
Sorted by cheapest first
Compare providers for flights from Columbia to Buffalo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Columbia to Buffalo in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Columbia, Missouri-Buffalo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Columbia, Missouri-Buffalo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Columbia, Missouri-Buffalo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Columbia, Missouri-Buffalo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Columbia, Missouri-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Columbia to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Columbia with our price prediction graph.
COU-BUF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Columbia to Buffalo
Reviews of airlines servicing Buffalo
Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated September 25, 2026.
Get a feel of what it's like to fly with United Airlines from Columbia to Buffalo by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.1
Food
6.7
Boarding
7.7
Overall
7.4
Comfort
7.3
Entertainment
7.1
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Crew
8.1
Food
6.7
Boarding
7.7
Overall
7.4
Comfort
7.3
Entertainment
7.1
Reviews
1 / 20
8.0
ExcellentAsha,Sep 2026
LGA - IAH
Related info for your journey
Find useful and relevant information for your journey from Columbia to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsLockport
Cheektowaga
Amherst
Williamsville
Orchard Park
Eden
Bowmansville
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Other flights to Buffalo
Explore flights to Buffalo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 25, 2026.
Complete your trip
Complete your trip to Buffalo by adding a car rental and/or hotel reservation to your travel itinerary.
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Columbia and Buffalo flights
Browse other Columbia and Buffalo flight options. Last updated on September 25, 2026.
Other flights from Columbia
Browse through other flights departing from Columbia. Flights are based on user searches made on Cheapflights and were last updated on September 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Columbia to Buffalo
Discover the top airline that operate flights from Columbia to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$293 | Average$363 | FlexibilityNo cancel fee | On-time69% |