HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Buffalo

$149+ Cheap flights from Mississippi to Buffalo (BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/14. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — BUF
oct. 17 — oct. 241
vie. 10/17
vie. 10/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Mississippi to Buffalo with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Mississippi to Buffalo

Keep the following information in mind while searching for Mississippi to Buffalo flight deals. Data was last updated septiembre 17, 2025.

Round-trip from

$294
(Kiwi.com)

One-way from

$149
(American Airlines)
From Mississippi to Buffalo
Search Deals
One-way flight from Mississippi to Buffalo
Search Deals

Find flight deals from Mississippi to Buffalo

Cheapest flights from Mississippi to Buffalo
Explore the most affordable flight options available from Mississippi to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 17, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/54:19 pmMEM - BUF
1 stop15h 31mMultiple Airlines
lun. 12/85:06 pmBUF - MEM
1 stop23h 08mMultiple Airlines
Deal found 9/14$251
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/317:00 amMEM - BUF
2 stops12h 53mMultiple Airlines
dom. 11/212:39 pmBUF - MEM
1 stop23h 11mMultiple Airlines
Deal found 9/16$294
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/211:01 pmJAN - BUF
1 stop4h 24mDelta
mié. 10/226:00 amBUF - JAN
1 stop5h 01mDelta
Deal found 9/16$297
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/217:15 amJAN - BUF
2 stops7h 01mDelta
mar. 10/2812:06 pmBUF - JAN
1 stop7h 27mDelta
Deal found 9/16$302
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/185:58 pmJAN - BUF
1 stop4h 41mDelta
mar. 10/214:35 pmBUF - JAN
1 stop7h 15mDelta
Deal found 9/16$305
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/182:54 pmJAN - BUF
2 stops6h 58mDelta
mar. 10/2812:06 pmBUF - JAN
1 stop7h 27mDelta
Deal found 9/16$310
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/185:32 amJAN - BUF
1 stop4h 29mDelta
sáb. 10/256:00 amBUF - JAN
1 stop5h 01mDelta
Deal found 9/16$313
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/218:08 amJAN - BUF
2 stops9h 10mAmerican Airlines
sáb. 10/254:00 pmBUF - JAN
2 stops9h 12mAmerican Airlines
Deal found 9/16$315
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 10/246:00 amMEM - BUF
1 stop10h 47mAmerican Airlines
mar. 10/285:14 amBUF - MEM
1 stop9h 29mAmerican Airlines
Deal found 9/15$317
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 10/215:32 amJAN - BUF
1 stop4h 29mDelta
vie. 10/247:30 pmBUF - JAN
1 stop4h 20mDelta
Deal found 9/16$326
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/152:54 pmJAN - BUF
2 stops7h 03mDelta
mié. 10/226:00 amBUF - JAN
1 stop7h 16mDelta
Deal found 9/17$333
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/188:50 amJAN - BUF
1 stop5h 38mDelta
vie. 10/247:30 pmBUF - JAN
1 stop4h 20mDelta
Deal found 9/16$334

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 17, 2025.
Use the filters below to find and compare flights from Mississippi to Buffalo that are best for you.

Fly from

Mississippi

Fly to

Buffalo

Route

Depart

Return

Price

MemphisBuffalo

MEM - BUF

MEMBUF

Memphis

vie. 12/5

4:19 pm-8:50 am

1 stop15h 31m

Buffalo

lun. 12/8

5:06 pm-3:14 pm

1 stop23h 08m

$251

MemphisBuffalo

MEM - BUF

MEMBUF

Memphis

vie. 10/31

7:00 am-8:53 pm

2 stops12h 53m

Buffalo

dom. 11/2

12:39 pm-10:50 am

1 stop23h 11m

$294

JacksonBuffalo

JAN - BUF

JANBUF

Jackson-Evers Intl

mié. 10/22

10:46 am-6:25 pm

1 stop6h 39m

Buffalo

mar. 10/28

12:06 pm-6:33 pm

1 stop7h 27m

$297

JacksonBuffalo

JAN - BUF

JANBUF

Jackson-Evers Intl

mié. 10/15

5:46 pm-11:43 pm

1 stop4h 57m

Buffalo

mié. 10/22

4:25 pm-11:10 pm

1 stop7h 45m

$297

JacksonBuffalo

JAN - BUF

JANBUF

Jackson-Evers Intl

mar. 10/21

7:15 am-3:16 pm

2 stops7h 01m

Buffalo

mar. 10/28

12:06 pm-6:33 pm

1 stop7h 27m

$302

JacksonBuffalo

JAN - BUF

JANBUF

Jackson-Evers Intl

mar. 10/21

8:08 am-3:35 pm

1 stop6h 27m

Buffalo

sáb. 10/25

7:38 pm-12:12 am

1 stop5h 34m

$305

MemphisBuffalo

MEM - BUF

MEMBUF

Memphis

mié. 2/18

6:30 am-1:48 pm

1 stop6h 18m

Buffalo

sáb. 2/21

6:00 am-12:43 pm

1 stop7h 43m

$305

GulfportBuffalo

GPT - BUF

GPTBUF

Gulfport Biloxi Regional

mié. 2/18

6:00 am-11:16 am

1 stop4h 16m

Buffalo

sáb. 2/21

6:00 am-9:41 am

1 stop4h 41m

$305

Baton RougeBuffalo

BTR - BUF

BTRBUF

Baton Rouge Ryan

mié. 2/18

6:00 am-5:26 pm

2 stops10h 26m

Buffalo

sáb. 2/21

6:00 am-12:54 pm

1 stop7h 54m

$310

JacksonBuffalo

JAN - BUF

JANBUF

Jackson-Evers Intl

sáb. 10/18

2:54 pm-10:52 pm

2 stops6h 58m

Buffalo

mar. 10/21

6:00 am-10:01 am

1 stop5h 01m

$310

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 39 results
1
2
3
4

Best time to book a flight from Mississippi to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Buffalo
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Buffalo from Mississippi?

    If you book a flight to Buffalo from Mississippi, you will be flying to Buffalo, which is the city’s only airport. Buffalo (BUF) is located 8.3 mi from the center of Buffalo.

  • How long is the flight from Mississippi to Buffalo?

    A quick flight from Mississippi to Buffalo can take about 4h 57m. Delta provides one of the quickest options available for as low as $297. Mississippi and Buffalo are separated by a distance of 959 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Mississippi to Buffalo one-way?

    One-way options have recently been found by users for as low as $149 on American Airlines. Other airlines that offer cheap prices include Delta from $224 and United Airlines from $482 one-way.

  • What are the most popular routes from Mississippi to Buffalo?

    The most popular route from Mississippi to Buffalo is Memphis - Buffalo. You may also consider Gulfport Biloxi Regional - Buffalo or Jackson-Evers Intl - Buffalo.

  • Can I find deals for flights from Mississippi to Buffalo that include hotel bookings?

    Yes. In addition to deals on Mississippi to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Buffalo.

  • Can I find deals for business class flights from Mississippi to Buffalo?

    Yes. Cheapflights offers flight deals from Mississippi to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mississippi to Buffalo?

    Currently, January is the cheapest month in which you can book a flight from Mississippi to Buffalo (average of $256). Flying from Mississippi to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Lockport
Orchard Park
Batavia
Williamsville
Eden
Amherst
West Seneca

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Mississippi to Buffalo

See prices for flight routes from nearby airports that may be better suited for you.
Los Angeles to John F Kennedy Intl flights
Dallas/Fort Worth to John F Kennedy Intl flights
San Francisco to John F Kennedy Intl flights
Dallas/Fort Worth to LaGuardia flights
O'Hare Intl to John F Kennedy Intl flights
O'Hare Intl to LaGuardia flights
Los Angeles to Newark flights
Los Angeles to LaGuardia flights
San Francisco to Newark flights
O'Hare Intl to Newark flights
Atlanta to LaGuardia flights
Dallas/Fort Worth to Newark flights
Miami to John F Kennedy Intl flights
Hobby to John F Kennedy Intl flights
Hobby to Newark flights
Atlanta to John F Kennedy Intl flights
Ontario to John F Kennedy Intl flights
San Francisco to LaGuardia flights
Hobby to LaGuardia flights
Miami to LaGuardia flights
Fort Lauderdale to Newark flights
Fort Lauderdale to LaGuardia flights
Miami to Newark flights
Denver to LaGuardia flights
Minneapolis to John F Kennedy Intl flights
Denver to John F Kennedy Intl flights
Atlanta to Newark flights
Raleigh to LaGuardia flights
George Bush Intcntl to Newark flights
Fort Lauderdale to John F Kennedy Intl flights
Charlotte to John F Kennedy Intl flights
Santa Ana to Newark flights
Burbank to Newark flights
Raleigh to John F Kennedy Intl flights
Orlando to John F Kennedy Intl flights
George Bush Intcntl to John F Kennedy Intl flights
Ontario to Newark flights
Minneapolis to LaGuardia flights
Austin to Newark flights
Seattle to Newark flights
Austin to John F Kennedy Intl flights
Tampa to John F Kennedy Intl flights
Minneapolis to Newark flights
Denver to Newark flights
Seattle to John F Kennedy Intl flights
George Bush Intcntl to LaGuardia flights
San Diego to John F Kennedy Intl flights
Sky Harbor Intl to John F Kennedy Intl flights
Santa Ana to LaGuardia flights
Cincinnati to John F Kennedy Intl flights

Top 2 airlines flying from Mississippi to Buffalo

Discover the top 2 airlines that operate flights from Mississippi to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$236Average$376FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$258Average$436FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.