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$131+ Cheap flights from Mississippi to Buffalo (BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/26. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — BUF
dic. 4 — dic. 111
jue. 12/4
jue. 12/11
1 adult, Economy
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Find flight deals from Mississippi to Buffalo

Cheapest flights from Mississippi to Buffalo
Explore the most affordable flight options available from Mississippi to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on noviembre 4, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/2510:07 amMEM - BUF
1 stop27h 26mMultiple Airlines
lun. 12/15:05 pmBUF - MEM
2 stops16h 57mMultiple Airlines
Deal found 11/4$244
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/107:39 amBTR - BUF
2 stops8h 31mDelta
mié. 12/1712:10 pmBUF - BTR
1 stop7h 04mDelta
Deal found 11/2$276
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/106:07 amBTR - BUF
2 stops9h 55mDelta
dom. 12/1412:10 pmBUF - BTR
1 stop7h 04mDelta
Deal found 11/2$294
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/106:07 amBTR - BUF
2 stops9h 55mDelta
lun. 12/151:16 pmBUF - BTR
2 stops9h 37mDelta
Deal found 11/2$299
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/26:33 amMOB - BUF
1 stop4h 34mAmerican Airlines
mar. 12/912:57 pmBUF - MOB
1 stop4h 53mAmerican Airlines
Deal found 11/3$309
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/126:59 pmBTR - BUF
2 stops14h 40mDelta
mié. 12/1712:10 pmBUF - BTR
1 stop7h 04mDelta
Deal found 11/2$313
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/1110:32 amBTR - BUF
1 stop5h 46mDelta
mié. 12/1712:10 pmBUF - BTR
1 stop7h 04mDelta
Deal found 11/2$314
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/34:41 pmMEM - BUF
1 stop6h 35mDelta
mié. 12/106:25 pmBUF - MEM
1 stop5h 58mDelta
Deal found 11/3$317
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/126:59 pmBTR - BUF
2 stops14h 40mDelta
mar. 12/161:16 pmBUF - BTR
2 stops7h 41mDelta
Deal found 11/2$318
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/1110:32 amBTR - BUF
1 stop5h 46mDelta
sáb. 12/131:16 pmBUF - BTR
2 stops8h 56mDelta
Deal found 11/2$319
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/36:45 amMEM - BUF
1 stop7h 15mSouthwest
mié. 12/1012:35 pmBUF - MEM
2 stops10h 25mSouthwest
Deal found 11/3$322
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 11/196:03 pmGPT - BUF
1 stop4h 47mDelta
dom. 11/2312:05 pmBUF - GPT
1 stop6h 08mDelta
Deal found 11/4$327

Cheap flight deals from Mississippi to Buffalo

Keep the following information in mind while searching for Mississippi to Buffalo flight deals. Data was last updated noviembre 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$299
(Delta)

One-way from

$131
(Kiwi.com)
Provider with most accurate pricing for Jackson-Evers Intl-Buffalo flight deals.
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Provider most trusted by Cheapflights users for Jackson-Evers Intl-Buffalo flights.
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From Mississippi to Buffalo
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One-way flight from Mississippi to Buffalo
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Mississippi to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 4, 2025.
Use the filters below to find and compare flights from Mississippi to Buffalo that are best for you.

Fly from

Mississippi

Fly to

Buffalo

Route

Depart

Return

Price

Baton RougeBuffalo

BTR - BUF

BTRBUF

Baton Rouge Ryan

mié. 12/10

7:39 am-5:10 pm

2 stops8h 31m

Buffalo

sáb. 12/13

12:10 pm-4:26 pm

1 stop5h 16m

$276

Baton RougeBuffalo

BTR - BUF

BTRBUF

Baton Rouge Ryan

mié. 12/10

7:39 am-5:10 pm

2 stops8h 31m

Buffalo

mié. 12/17

12:10 pm-6:14 pm

1 stop7h 04m

$276

Baton RougeBuffalo

BTR - BUF

BTRBUF

Baton Rouge Ryan

mié. 12/10

6:07 am-5:02 pm

2 stops9h 55m

Buffalo

lun. 12/15

12:10 pm-6:14 pm

1 stop7h 04m

$294

Baton RougeBuffalo

BTR - BUF

BTRBUF

Baton Rouge Ryan

mié. 12/10

7:39 am-5:10 pm

2 stops8h 31m

Buffalo

dom. 12/14

6:12 am-1:36 pm

2 stops8h 24m

$299

Baton RougeBuffalo

BTR - BUF

BTRBUF

Baton Rouge Ryan

sáb. 12/6

10:34 am-10:58 pm

2 stops11h 24m

Buffalo

dom. 12/7

6:12 am-1:36 pm

2 stops8h 24m

$299

MobileBuffalo

MOB - BUF

MOBBUF

Mobile

mar. 12/2

6:33 am-12:07 pm

1 stop4h 34m

Buffalo

mar. 12/9

12:57 pm-4:50 pm

1 stop4h 53m

$309

Baton RougeBuffalo

BTR - BUF

BTRBUF

Baton Rouge Ryan

vie. 12/12

6:59 pm-10:39 am

2 stops14h 40m

Buffalo

mié. 12/17

12:10 pm-6:14 pm

1 stop7h 04m

$313

Baton RougeBuffalo

BTR - BUF

BTRBUF

Baton Rouge Ryan

vie. 12/12

6:59 pm-10:39 am

2 stops14h 40m

Buffalo

mar. 12/16

12:10 pm-6:14 pm

1 stop7h 04m

$313

Baton RougeBuffalo

BTR - BUF

BTRBUF

Baton Rouge Ryan

jue. 12/11

10:32 am-5:18 pm

1 stop5h 46m

Buffalo

mié. 12/17

12:10 pm-6:14 pm

1 stop7h 04m

$314

Baton RougeBuffalo

BTR - BUF

BTRBUF

Baton Rouge Ryan

jue. 12/11

10:32 am-5:18 pm

1 stop5h 46m

Buffalo

mar. 12/16

12:10 pm-6:14 pm

1 stop7h 04m

$314

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/3

Showing 1-10 of 51 results
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Best time to book a flight from Mississippi to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Mississippi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mississippi to Buffalo
No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Mississippi to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Buffalo from Mississippi?

    If you book a flight to Buffalo from Mississippi, you will be flying to Buffalo, which is the city’s only airport. Buffalo (BUF) is located 8.3 mi from the center of Buffalo.

  • How long is the flight from Mississippi to Buffalo?

    A quick flight from Mississippi to Buffalo can take about 4h 34m. Delta provides one of the quickest options available for as low as $309. Mississippi and Buffalo are separated by a distance of 994 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Mississippi to Buffalo one-way?

    One-way options have recently been found by users for as low as $164 on American Airlines. Other airlines that offer cheap prices include Delta from $169 and Frontier from $264 one-way.

  • What are the most popular routes from Mississippi to Buffalo?

    The most popular route from Mississippi to Buffalo is Memphis - Buffalo. You may also consider Baton Rouge Ryan - Buffalo or Jackson-Evers Intl - Buffalo.

  • Can I find deals for flights from Mississippi to Buffalo that include hotel bookings?

    Yes. In addition to deals on Mississippi to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mississippi to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mississippi to Buffalo.

  • Can I find deals for business class flights from Mississippi to Buffalo?

    Yes. Cheapflights offers flight deals from Mississippi to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Lockport
Cheektowaga
Orchard Park
Batavia
Williamsville
Eden
Amherst
West Seneca

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Top airline flying from Mississippi to Buffalo

Discover the top airline that operate flights from Mississippi to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated noviembre 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$258Average$436FlexibilityNo cancel feeOn-time71%

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