$128+ Cheap flights from Mesa, AZ to Buffalo (BUF)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/12. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — BUF
Aug 16 — Aug 231
Round-trip
1 adult, Economy
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Find cheap flights from Mesa to Buffalo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Mesa to Buffalo are usually found in March or August, booked 71 days in advance, depart on a Thursday or Tuesday and return on a Thursday
Cheap flight deals from Mesa to Buffalo
Cheapest
Best
Last-minute
One-way
Cheapest flights from Mesa to BuffaloExplore the most affordable flight options available from Mesa to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 17, 2026.
Explore the most affordable flight options available from Mesa to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 17, 2026.
This Frontier deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/89:50 pm
PHX
- BUF
1 stop9h 39m
Frontier
Fri 8/142:48 pm
BUF
- PHX
1 stop7h 56m
Frontier
Deal found 7/13![Frontier logo]()
$258
This Frontier deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1211:31 pm
PHX
- BUF
1 stop9h 47m
Frontier
Sat 10/241:13 pm
BUF
- PHX
1 stop11h 26m
Frontier
Deal found 7/15![Frontier logo]()
$263
This CheapOair deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1211:23 pm
PHX
- BUF
1 stop8h 06m
Frontier
Sun 8/169:33 pm
BUF
- PHX
1 stop16h 02m
Frontier
Deal found 7/14![Frontier logo]()
$265
This CheapOair deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3112:12 am
PHX
- BUF
1 stop17h 55m
Frontier
Sat 8/810:02 pm
BUF
- PHX
1 stop15h 33m
Frontier
Deal found 7/13![Frontier logo]()
$268
This Orbitz deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2011:23 pm
PHX
- BUF
1 stop8h 06m
Frontier
Wed 7/227:57 pm
BUF
- PHX
1 stop17h 33m
Frontier
Deal found 7/16![Frontier logo]()
$272
This CheapOair deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1012:12 am
PHX
- BUF
1 stop15h 54m
Frontier
Sat 8/1512:28 pm
BUF
- PHX
1 stop12h 48m
Frontier
Deal found 7/15![Frontier logo]()
$273
This CheapOair deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2711:23 pm
PHX
- BUF
1 stop8h 06m
Frontier
Thu 7/309:29 pm
BUF
- PHX
1 stop16h 01m
Frontier
Deal found 7/15![Frontier logo]()
$275
This Expedia deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/259:50 pm
PHX
- BUF
1 stop9h 39m
Frontier
Sat 8/110:02 pm
BUF
- PHX
1 stop15h 28m
Frontier
Deal found 7/12![Frontier logo]()
$287
This Southwest deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:00 am
PHX
- BUF
1 stop6h 10m
Southwest
Wed 10/74:25 pm
BUF
- PHX
1 stop9h 10m
Southwest
Deal found 7/16![Southwest logo]()
$292
Best flights from Mesa to BuffaloDiscover carefully curated flight deals from Mesa to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 17, 2026.
Discover carefully curated flight deals from Mesa to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 17, 2026.
This Southwest deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2210:35 am
PHX
- BUF
2 stops7h 00m
Southwest
Tue 9/2912:00 pm
BUF
- PHX
1 stop8h 05m
Southwest
Deal found 7/13![Southwest logo]()
$302
This United Airlines deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:20 am
PHX
- BUF
2 stops9h 40m
United Airlines
Sat 8/155:58 pm
BUF
- PHX
1 stop7h 01m
United Airlines
Deal found 7/16![United Airlines logo]()
$312
This Trip.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/512:12 am
PHX
- BUF
1 stop13h 20m
Frontier
Sun 8/99:33 pm
BUF
- PHX
1 stop16h 02m
Frontier
Deal found 7/12![Frontier logo]()
$361
This Southwest deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:15 am
PHX
- BUF
2 stops8h 30m
Southwest
Sat 8/1510:50 am
BUF
- PHX
1 stop9h 10m
Southwest
Deal found 7/17![Southwest logo]()
$322
This Southwest deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:45 am
PHX
- BUF
2 stops7h 15m
Southwest
Tue 9/298:55 am
BUF
- PHX
2 stops9h 10m
Southwest
Deal found 7/13![Southwest logo]()
$358
This United Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2211:32 am
PHX
- BUF
1 stop8h 05m
United Airlines
Sat 9/2610:40 am
BUF
- PHX
2 stops9h 34m
United Airlines
Deal found 7/13![United Airlines logo]()
$402
This United Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1811:52 pm
PHX
- BUF
1 stop6h 37m
United Airlines
Sat 10/247:00 am
BUF
- PHX
2 stops14h 35m
United Airlines
Deal found 7/15![United Airlines logo]()
$402
This Southwest deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:40 am
PHX
- BUF
1 stop8h 05m
Southwest
Sun 10/117:20 pm
BUF
- PHX
Nonstop4h 40m
Southwest
Deal found 7/15![Southwest logo]()
$387
This United Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1210:18 am
PHX
- BUF
2 stops10h 26m
United Airlines
Sun 8/166:55 am
BUF
- PHX
1 stop7h 13m
United Airlines
Deal found 7/14![United Airlines logo]()
$402
This Southwest deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2210:35 am
PHX
- BUF
2 stops7h 00m
Southwest
Sun 9/276:20 am
BUF
- PHX
2 stops9h 20m
Southwest
Deal found 7/15![Southwest logo]()
$398
This United Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1411:52 pm
PHX
- BUF
1 stop6h 37m
United Airlines
Sat 10/1710:40 am
BUF
- PHX
2 stops13h 09m
United Airlines
Deal found 7/13![United Airlines logo]()
$403
Last-minute flights from Mesa to BuffaloDiscover last-minute flight deals from Mesa to Buffalo. Data last updated July 17, 2026 and is based on user searches.
Discover last-minute flight deals from Mesa to Buffalo. Data last updated July 17, 2026 and is based on user searches.
This Orbitz deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2011:23 pm
PHX
- BUF
1 stop8h 06m
Frontier
Wed 7/227:57 pm
BUF
- PHX
1 stop17h 33m
Frontier
Deal found 7/16![Frontier logo]()
$272
This Expedia deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/259:50 pm
PHX
- BUF
1 stop9h 39m
Frontier
Sat 8/110:02 pm
BUF
- PHX
1 stop15h 28m
Frontier
Deal found 7/12![Frontier logo]()
$287
This CheapOair deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2711:23 pm
PHX
- BUF
1 stop8h 06m
Frontier
Thu 7/309:29 pm
BUF
- PHX
1 stop16h 01m
Frontier
Deal found 7/15![Frontier logo]()
$275
This Frontier deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2911:23 pm
PHX
- BUF
1 stop8h 06m
Frontier
Wed 8/52:48 pm
BUF
- PHX
1 stop10h 28m
Frontier
Deal found 7/15![Frontier logo]()
$298
This CheapOair deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/3112:12 am
PHX
- BUF
1 stop17h 55m
Frontier
Sat 8/810:02 pm
BUF
- PHX
1 stop15h 33m
Frontier
Deal found 7/13![Frontier logo]()
$268
This Frontier deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/89:50 pm
PHX
- BUF
1 stop9h 39m
Frontier
Fri 8/142:48 pm
BUF
- PHX
1 stop7h 56m
Frontier
Deal found 7/13![Frontier logo]()
$258
This CheapOair deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1012:12 am
PHX
- BUF
1 stop15h 54m
Frontier
Sat 8/1512:28 pm
BUF
- PHX
1 stop12h 48m
Frontier
Deal found 7/15![Frontier logo]()
$273
This CheapOair deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1211:23 pm
PHX
- BUF
1 stop8h 06m
Frontier
Sun 8/169:33 pm
BUF
- PHX
1 stop16h 02m
Frontier
Deal found 7/14![Frontier logo]()
$265
This Delta deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2111:05 pm
PHX
- BUF
1 stop6h 10m
Delta
Fri 8/286:05 am
BUF
- PHX
1 stop9h 03m
Delta
Deal found 7/13![Delta logo]()
$297
One-way flights from Mesa to BuffaloSearch for one-way flight options from Mesa to Buffalo. Find affordable one-way fares based on user searches. Data last updated July 17, 2026.
Search for one-way flight options from Mesa to Buffalo. Find affordable one-way fares based on user searches. Data last updated July 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1211:31 pm
PHX
- BUF
1 stop9h 47m
Frontier
Deal found 7/12![Frontier logo]()
$128
This Priceline deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1211:23 pm
PHX
- BUF
1 stop8h 06m
Frontier
Deal found 7/13![Frontier logo]()
$129
This Frontier deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1010:44 pm
PHX
- BUF
1 stop10h 37m
Frontier
Deal found 7/15![Frontier logo]()
$135
This Booking.com deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/259:50 pm
PHX
- BUF
1 stop9h 39m
Frontier
Deal found 7/13![Frontier logo]()
$136
This Frontier deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1710:44 pm
PHX
- BUF
1 stop10h 37m
Frontier
Deal found 7/15![Frontier logo]()
$140
This CheapOair deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/2712:12 am
PHX
- BUF
1 stop15h 54m
Frontier
Deal found 7/14![Frontier logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/139:58 pm
PHX
- BUF
2 stops44h 09m
Frontier
Deal found 7/16![Frontier logo]()
$144
This CheapOair deal was found by Cheapflights users on 7/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2112:12 am
PHX
- BUF
1 stop15h 54m
Frontier
Deal found 7/17![Frontier logo]()
$147
This Delta deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/1311:59 pm
PHX
- BUF
1 stop8h 13m
Delta
Deal found 7/14![Delta logo]()
$149
This Kiwi.com deal was found by Cheapflights users on 7/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/109:04 am
PHX
- BUF
2 stops49h 49m
Frontier
Deal found 7/16![Frontier logo]()
$152
Find flight deals from Mesa to Buffalo
Keep the following information in mind while searching for Mesa to Buffalo flight deals. Data was last updated July 17, 2026.
Round-trip from | $258 (Frontier) |
|---|---|
One-way from | $128 (Kiwi.com) |
Popular in | November |
Cheapest in | March |
Average price | $387 |
Cheapflights Fare Finder
Customize your flight search to find flights from Mesa to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 17, 2026.
Use the filters below to find and compare flights from Mesa to Buffalo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PhoenixBuffalo
PHX - BUF
PHXBUF
Phoenix Sky Harbor Intl
Tue 9/22
10:35 am-8:35 pm
2 stops7h 00m
Buffalo
Tue 9/29
12:00 pm-5:05 pm
1 stop8h 05m
$302
PhoenixBuffalo
PHX - BUF
PHXBUF
Phoenix Sky Harbor Intl
Tue 8/11
6:20 am-7:00 pm
2 stops9h 40m
Buffalo
Sat 8/15
5:58 pm-9:59 pm
1 stop7h 01m
$312
PhoenixBuffalo
PHX - BUF
PHXBUF
Phoenix Sky Harbor Intl
Tue 8/11
6:15 am-5:45 pm
2 stops8h 30m
Buffalo
Sat 8/15
10:50 am-5:00 pm
1 stop9h 10m
$322
PhoenixBuffalo
PHX - BUF
PHXBUF
Phoenix Sky Harbor Intl
Sat 9/26
5:45 am-4:00 pm
2 stops7h 15m
Buffalo
Tue 9/29
8:55 am-3:05 pm
2 stops9h 10m
$358
PhoenixBuffalo
PHX - BUF
PHXBUF
Phoenix Sky Harbor Intl
Wed 8/5
12:12 am-4:32 pm
1 stop13h 20m
Buffalo
Sun 8/9
9:33 pm-10:35 am
1 stop16h 02m
$361
Quickest round-trip
PhoenixBuffalo
PHX - BUF
PHXBUF
Phoenix Sky Harbor Intl
Wed 9/30
6:40 am-5:45 pm
1 stop8h 05m
Buffalo
Sun 10/11
7:20 pm-9:00 pm
Nonstop4h 40m
$387
PhoenixBuffalo
PHX - BUF
PHXBUF
Phoenix Sky Harbor Intl
Tue 9/22
10:35 am-8:35 pm
2 stops7h 00m
Buffalo
Sun 9/27
6:20 am-12:40 pm
2 stops9h 20m
$398
PhoenixBuffalo
PHX - BUF
PHXBUF
Phoenix Sky Harbor Intl
Tue 9/22
11:32 am-10:37 pm
1 stop8h 05m
Buffalo
Sat 9/26
10:40 am-5:14 pm
2 stops9h 34m
$402
PhoenixBuffalo
PHX - BUF
PHXBUF
Phoenix Sky Harbor Intl
Sun 10/18
11:52 pm-9:29 am
1 stop6h 37m
Buffalo
Sat 10/24
7:00 am-6:35 pm
2 stops14h 35m
$402
PhoenixBuffalo
PHX - BUF
PHXBUF
Phoenix Sky Harbor Intl
Wed 8/12
10:18 am-11:44 pm
2 stops10h 26m
Buffalo
Sun 8/16
6:55 am-11:08 am
1 stop7h 13m
$402
Showing 1-10 of 21 resultsSorted by cheapest first
Best time to book a flight from Mesa to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Mesa with our price prediction graph.
PHX-BUF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mesa to Buffalo
MS9-BUF
PHX-BUF
What is the cheapest time of day to fly from MS9 to BUF?
Find hourly flight availability from Mesa to Buffalo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 17, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mesa to Buffalo as you normally would.
How much does it cost to fly round-trip from Mesa to Buffalo?
Reviews of airlines servicing Buffalo
Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated July 17, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Mesa to Buffalo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Overall
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Overall
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Overall
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Overall
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Overall
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Mesa to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsLockport
Cheektowaga
Amherst
Williamsville
Orchard Park
Eden
Bowmansville
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Top 6 airlines flying from Mesa to Buffalo
Discover the top 6 airlines that operate flights from Mesa to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$127 | Average$296 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$177 | Average$317 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$236 | Average$369 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$262 | Average$454 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$268 | Average$305 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$296 | Average$416 | FlexibilityNo cancel fee | On-time71% |