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$79+ Cheap flights from Mesa, AZ to Buffalo (BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/22. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — BUF
Aug 26 — Sep 21
Tue 8/26
Tue 9/2
1 adult, Economy
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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

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Cheapflights Tip: The best prices from Mesa to Buffalo are usually found in June or September, booked 25 days in advance, depart on a Friday or Monday and return on a Friday

Cheap flight deals from Mesa to Buffalo

Keep the following information in mind while searching for Mesa to Buffalo flight deals. Data was last updated August 21, 2025.

Round-trip from

$151
(Priceline)

One-way from

$79
(Cheapflightsfares)

Popular in

February

Cheapest in

June

Average price

$360
From Mesa to Buffalo
Search Deals
One-way flight from Mesa to Buffalo
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Highest demand for flights based on searches. 10% potential increase in price ($44 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Mesa to Buffalo

Cheapest flights from Mesa to Buffalo
Explore the most affordable flight options available from Mesa to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 21, 2025.

This Priceline deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/177:21 amPHX - BUF
1 stop6h 08mFrontier
Mon 10/205:24 pmBUF - PHX
1 stop7h 52mFrontier
Deal found 8/21$151
This Priceline deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/196:36 amPHX - BUF
1 stop6h 26mFrontier
Mon 9/224:58 pmBUF - PHX
1 stop9h 59mFrontier
Deal found 8/20$178
This Priceline deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/227:00 amPHX - BUF
1 stop6h 03mFrontier
Fri 9/264:57 pmBUF - PHX
1 stop10h 00mFrontier
Deal found 8/21$200
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/218:37 amPHX - BUF
1 stop28h 26mFrontier
Sun 9/284:57 pmBUF - PHX
1 stop18h 03mFrontier
Deal found 8/21$210
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/205:07 pmPHX - BUF
1 stop19h 55mFrontier
Sun 9/284:57 pmBUF - PHX
1 stop18h 03mFrontier
Deal found 8/21$212
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/188:20 pmPHX - BUF
1 stop16h 42mFrontier
Sun 9/284:57 pmBUF - PHX
1 stop18h 03mFrontier
Deal found 8/21$225
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/218:37 amPHX - BUF
1 stop28h 26mFrontier
Fri 9/264:57 pmBUF - PHX
1 stop26h 05mFrontier
Deal found 8/21$243
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/205:07 pmPHX - BUF
1 stop19h 55mFrontier
Fri 9/264:57 pmBUF - PHX
1 stop26h 05mFrontier
Deal found 8/21$245
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/188:20 pmPHX - BUF
1 stop16h 42mFrontier
Fri 9/264:57 pmBUF - PHX
1 stop26h 05mFrontier
Deal found 8/21$258
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/169:59 pmPHX - BUF
1 stop15h 30mFrontier
Fri 10/245:24 pmBUF - PHX
1 stop24h 40mFrontier
Deal found 8/21$263
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/205:07 pmPHX - BUF
1 stop19h 55mFrontier
Thu 9/257:41 pmBUF - PHX
2 stops22h 40mFrontier
Deal found 8/21$266
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/199:59 pmPHX - BUF
1 stop15h 30mFrontier
Mon 10/275:24 pmBUF - PHX
1 stop21h 51mFrontier
Deal found 8/21$267

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mesa to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 21, 2025.
Use the filters below to find and compare flights from Mesa to Buffalo that are best for you.

Fly from

Mesa

Fly to

Buffalo

Route

Depart

Return

Price

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Fri 10/17

7:21 am-4:29 pm

1 stop6h 08m

Buffalo

Mon 10/20

5:24 pm-10:16 pm

1 stop7h 52m

$151

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Fri 9/19

6:36 am-4:02 pm

1 stop6h 26m

Buffalo

Mon 9/22

4:58 pm-11:57 pm

1 stop9h 59m

$178

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Sun 9/21

8:37 am-4:03 pm

1 stop28h 26m

Buffalo

Sun 9/28

4:57 pm-8:00 am

1 stop18h 03m

$210

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Sat 9/20

5:07 pm-4:02 pm

1 stop19h 55m

Buffalo

Sun 9/28

4:57 pm-8:00 am

1 stop18h 03m

$212

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Thu 9/18

8:20 pm-4:02 pm

1 stop16h 42m

Buffalo

Sun 9/28

4:57 pm-8:00 am

1 stop18h 03m

$225

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Sun 9/21

8:37 am-4:03 pm

1 stop28h 26m

Buffalo

Fri 9/26

4:57 pm-4:02 pm

1 stop26h 05m

$243

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Sat 9/20

5:07 pm-4:02 pm

1 stop19h 55m

Buffalo

Thu 9/25

7:41 pm-3:21 pm

2 stops22h 40m

$266

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Sun 10/19

9:59 pm-4:29 pm

1 stop15h 30m

Buffalo

Mon 10/27

5:24 pm-12:15 pm

1 stop21h 51m

$267

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Sat 10/25

9:59 pm-9:20 am

1 stop8h 21m

Buffalo

Tue 10/28

12:15 pm-8:57 pm

1 stop11h 42m

$269

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Mon 10/20

9:59 pm-9:03 am

1 stop8h 04m

Buffalo

Sat 10/25

3:59 pm-8:56 pm

1 stop7h 57m

$269

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/21

Showing 1-10 of 21 results
1
2
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Best time to book a flight from Mesa to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Mesa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mesa to Buffalo

How far ahead should I book a flight from Mesa to Buffalo?

Use this chart to determine the optimal time to book a round-trip flight from Mesa to Buffalo. Price data was last updated on August 8, 2025.

Booking 25 days in advance of your planned departure date is, on average, the best time to get cheap flights from Mesa to Buffalo. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Mesa to Buffalo?

Currently, January is the cheapest month in which you can book a flight from Mesa to Buffalo (average of $256). Flying from Mesa to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS9 to BUF?

Find hourly flight availability from Mesa to Buffalo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 21, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mesa to Buffalo as you normally would.

What is the cheapest day to fly from Mesa to Buffalo?

Use this chart to determine the cheapest time to fly round-trip from Mesa to Buffalo. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Mesa to Buffalo flight should consider departing on Sunday evenings when fares are most often at their lowest. Tuesday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated August 21, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Mesa to Buffalo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,245 reviews

Entertainment

7.5

Comfort

8.0

Food

7.0

Boarding

8.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,245 reviews
Southwest
8.0
Very good
4,245 reviews

Entertainment

7.5

Comfort

8.0

Food

7.0

Boarding

8.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,981 reviews
Southwest
8.0
Very good
4,245 reviews

Entertainment

7.5

Comfort

8.0

Food

7.0

Boarding

8.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,934 reviews
Southwest
8.0
Very good
4,245 reviews

Entertainment

7.5

Comfort

8.0

Food

7.0

Boarding

8.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,245 reviews

Entertainment

7.5

Comfort

8.0

Food

7.0

Boarding

8.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Frontier
5.8
Fair
3,207 reviews
Southwest
8.0
Very good
4,245 reviews

Entertainment

7.5

Comfort

8.0

Food

7.0

Boarding

8.1

Crew

8.6

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Mesa to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Buffalo from Mesa?

    If you book a flight to Buffalo from Mesa, you will be flying to Buffalo, which is the city’s only airport. Buffalo (BUF) is located 8.3 mi from the center of Buffalo. There are 0 flights from Mesa to Buffalo per day from 6 different airlines.

  • How long is the flight from Mesa to Buffalo?

    There are many flights that can get you from Mesa to Buffalo in 6h 08m. Fly via Frontier to get the fastest option. The distance from Mesa to Buffalo is about 1906 mi.

  • What are the cheapest flights from Mesa to Buffalo?

    On average you can expect to pay $568 for a flight from Mesa to Buffalo. The cheapest flight overall is $347 while the most popular route, (Phoenix Sky Harbor Intl - Buffalo) is currently priced at $273.

  • Can I find deals for flights from Mesa to Buffalo that include hotel bookings?

    Yes. In addition to deals on Mesa to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mesa to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mesa to Buffalo.

  • Can I find deals for business class flights from Mesa to Buffalo?

    Yes. Cheapflights offers flight deals from Mesa to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mesa to Buffalo?

    Currently, January is the cheapest month in which you can book a flight from Mesa to Buffalo (average of $256). Flying from Mesa to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Lockport
Orchard Park
Batavia
Williamsville
Eden
Amherst
West Seneca

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

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See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Mesa to Buffalo

Discover the top 6 airlines that operate flights from Mesa to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 21, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$124Average$338FlexibilityNo cancel feeOn-time62%
FrontierCheapest$166Average$294FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$248Average$338FlexibilityNo cancel feeOn-time69%
DeltaCheapest$248Average$333FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$360FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$313Average$488FlexibilityNo cancel feeOn-time63%

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