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$88+ Cheap flights from Mesa, AZ to Buffalo (BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/14. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — BUF
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Cheapflights Tip: The best prices from Mesa to Buffalo are usually found in June or August, booked 25 days in advance, depart on a Friday or Tuesday and return on a Tuesday

Cheap flight deals from Mesa to Buffalo

Keep the following information in mind while searching for Mesa to Buffalo flight deals. Data was last updated October 30, 2025.

Round-trip from

$207
(American Airlines)

One-way from

$88
(Trip.com)

Popular in

January

Cheapest in

June

Average price

$438
From Mesa to Buffalo
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One-way flight from Mesa to Buffalo
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Highest demand for flights based on searches. 9% potential increase in price ($42 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Mesa to Buffalo

Cheapest flights from Mesa to Buffalo
Explore the most affordable flight options available from Mesa to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/135:10 amPHX - BUF
1 stop8h 46mAmerican Airlines
Tue 11/186:32 amBUF - PHX
1 stop8h 54mAmerican Airlines
Deal found 10/30$207
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2212:59 amPHX - BUF
1 stop9h 53mFrontier
Sun 1/119:08 amBUF - PHX
2 stops38h 18mFrontier
Deal found 10/29$249
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/52:36 pmPHX - BUF
1 stop7h 08mAmerican Airlines
Sun 11/96:32 amBUF - PHX
1 stop7h 43mAmerican Airlines
Deal found 10/28$253
This JetBlue deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2410:28 pmPHX - BUF
1 stop9h 51mJetBlue
Wed 1/72:45 pmBUF - PHX
1 stop9h 00mJetBlue
Deal found 10/28$256
This JetBlue deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2410:28 pmPHX - BUF
1 stop9h 51mJetBlue
Fri 1/92:45 pmBUF - PHX
1 stop9h 00mJetBlue
Deal found 10/28$260
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2212:59 amPHX - BUF
1 stop9h 53mFrontier
Mon 1/129:08 amBUF - PHX
2 stops16h 28mFrontier
Deal found 10/29$266
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/175:10 amPHX - BUF
1 stop8h 46mAmerican Airlines
Mon 11/243:27 pmBUF - PHX
1 stop8h 35mAmerican Airlines
Deal found 10/28$267
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/177:43 pmPHX - BUF
2 stops15h 29mFrontier
Wed 12/3111:08 amBUF - PHX
1 stop14h 41mFrontier
Deal found 10/28$273
This Frontier deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2212:59 amPHX - BUF
1 stop9h 53mFrontier
Mon 1/510:43 amBUF - PHX
1 stop15h 06mFrontier
Deal found 10/28$276
This CheapOair deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1010:20 pmPHX - BUF
1 stop10h 35mJetBlue
Mon 12/156:45 amBUF - PHX
1 stop31h 00mJetBlue
Deal found 10/29$281
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2212:59 amPHX - BUF
1 stop9h 53mFrontier
Wed 12/315:44 pmBUF - PHX
2 stops31h 28mFrontier
Deal found 10/29$284
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2312:59 amPHX - BUF
1 stop17h 41mFrontier
Thu 1/89:08 amBUF - PHX
2 stops32h 05mFrontier
Deal found 10/28$285

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mesa to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Mesa to Buffalo that are best for you.

Fly from

Mesa

Fly to

Buffalo

Route

Depart

Return

Price

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Wed 12/24

10:28 pm-10:19 am

1 stop9h 51m

Buffalo

Wed 1/7

2:45 pm-9:45 pm

1 stop9h 00m

$256

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Mon 12/22

12:59 am-12:52 pm

1 stop9h 53m

Buffalo

Fri 1/9

1:37 pm-1:49 pm

2 stops26h 12m

$295

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Sun 3/1

10:40 pm-8:29 am

1 stop7h 49m

Buffalo

Tue 3/3

7:45 am-2:00 pm

1 stop8h 15m

$306

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Sat 12/20

4:02 pm-11:28 pm

1 stop5h 26m

Buffalo

Sat 1/10

11:51 am-10:42 pm

1 stop12h 51m

$325

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Thu 12/25

12:43 pm-10:33 pm

1 stop7h 50m

Buffalo

Thu 1/8

6:00 am-12:24 pm

1 stop8h 24m

$327

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Sat 12/20

4:02 pm-11:28 pm

1 stop5h 26m

Buffalo

Thu 1/8

6:00 am-12:24 pm

1 stop8h 24m

$327

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Sat 12/20

4:02 pm-11:28 pm

1 stop5h 26m

Buffalo

Wed 1/7

6:03 am-11:14 am

1 stop7h 11m

$327

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Thu 12/25

12:43 pm-10:33 pm

1 stop7h 50m

Buffalo

Tue 1/6

5:44 pm-10:47 pm

1 stop7h 03m

$327

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Wed 12/24

12:43 pm-10:33 pm

1 stop7h 50m

Buffalo

Mon 1/5

5:44 pm-10:47 pm

1 stop7h 03m

$327

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Tue 1/27

11:59 pm-9:04 am

1 stop7h 05m

$109

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 19 results
1
2

Best time to book a flight from Mesa to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Mesa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mesa to Buffalo

How far ahead should I book a flight from Mesa to Buffalo?

Use this chart to determine the optimal time to book a round-trip flight from Mesa to Buffalo. Price data was last updated on October 24, 2025.

Booking 25 days in advance of your planned departure date is, on average, the best time to get cheap flights from Mesa to Buffalo. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Mesa to Buffalo?

Currently, July is the cheapest month in which you can book a flight from Mesa to Buffalo (average of $138). Flying from Mesa to Buffalo in October is currently the most expensive (average of $268). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS9 to BUF?

Find hourly flight availability from Mesa to Buffalo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

One of the essential ways to save on airfare from Mesa to Buffalo is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 53% on airfare.

What is the cheapest day to fly from Mesa to Buffalo?

Use this chart to determine the cheapest time to fly round-trip from Mesa to Buffalo. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Mesa to Buffalo flight should consider departing on Saturday mornings when fares are most often at their lowest. Friday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Mesa to Buffalo?

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated October 30, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Mesa to Buffalo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Crew

8.6

Overall

8.0

Entertainment

7.5

Food

7.0

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Crew

8.6

Overall

8.0

Entertainment

7.5

Food

7.0

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
7,993 reviews
Southwest
8.0
Very good
4,242 reviews

Crew

8.6

Overall

8.0

Entertainment

7.5

Food

7.0

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,998 reviews
Southwest
8.0
Very good
4,242 reviews

Crew

8.6

Overall

8.0

Entertainment

7.5

Food

7.0

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,030 reviews
Southwest
8.0
Very good
4,242 reviews

Crew

8.6

Overall

8.0

Entertainment

7.5

Food

7.0

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Frontier
5.8
Fair
3,123 reviews
Southwest
8.0
Very good
4,242 reviews

Crew

8.6

Overall

8.0

Entertainment

7.5

Food

7.0

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Mesa to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Buffalo from Mesa?

    If you book a flight to Buffalo from Mesa, you will be flying to Buffalo, which is the city’s only airport. Buffalo (BUF) is located 8.3 mi from the center of Buffalo. There are 0 flights from Mesa to Buffalo per day from 6 different airlines.

  • How long is the flight from Mesa to Buffalo?

    There are many flights that can get you from Mesa to Buffalo in 5h 26m. Fly via JetBlue, Frontier, or Delta to get the fastest option. The distance from Mesa to Buffalo is about 1906 mi. This flight may include one or multiple stops.

  • What are the cheapest flights from Mesa to Buffalo?

    On average you can expect to pay $451 for a flight from Mesa to Buffalo. The cheapest flight overall is $198 while the most popular route, (Phoenix Sky Harbor Intl - Buffalo) is currently priced at $253.

  • Can I find deals for flights from Mesa to Buffalo that include hotel bookings?

    Yes. In addition to deals on Mesa to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mesa to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mesa to Buffalo.

  • Can I find deals for business class flights from Mesa to Buffalo?

    Yes. Cheapflights offers flight deals from Mesa to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mesa to Buffalo?

    Currently, July is the cheapest month in which you can book a flight from Mesa to Buffalo (average of $138). Flying from Mesa to Buffalo in October is currently the most expensive (average of $268). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Lockport
Cheektowaga
Orchard Park
Batavia
Williamsville
Eden
Amherst
West Seneca

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Mesa to Buffalo

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Mesa to Buffalo

Discover the top 6 airlines that operate flights from Mesa to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$151Average$293FlexibilityNo cancel feeOn-time62%
JetBlueCheapest$198Average$324FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$248Average$338FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$248Average$381FlexibilityNo cancel feeOn-time71%
DeltaCheapest$256Average$338FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$313Average$485FlexibilityNo cancel feeOn-time63%

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