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$105+ Cheap flights from Mesa, AZ to Buffalo (BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/10. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — BUF
May 5 — May 121
Mon 5/5
Mon 5/12
1 adult, Economy
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Cheapflights Tip: The best prices from Mesa to Buffalo are usually found in September or August, booked 72 days in advance, depart on a Monday or Thursday and return on a Wednesday

Cheap flight deals from Mesa to Buffalo

Keep the following information in mind while searching for Mesa to Buffalo flight deals. Data was last updated April 30, 2025.

Round-trip from

$201
(CheapOair)

One-way from

$105
(Frontier)

Popular in

February

Cheapest in

September

Average price

$306
From Mesa to Buffalo
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One-way flight from Mesa to Buffalo
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Highest demand for flights based on searches. 14% potential increase in price ($61 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from Mesa to Buffalo

Cheapest flights from Mesa to Buffalo
Explore the most affordable flight options available from Mesa to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.

This CheapOair deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/173:11 pmPHX - BUF
1 stop14h 50mFrontier
Sat 5/241:08 pmBUF - PHX
1 stop30h 19mFrontier
Deal found 4/29$201
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/711:20 pmPHX - BUF
1 stop7h 36mUnited Airlines
Fri 6/136:15 amBUF - PHX
1 stop7h 05mUnited Airlines
Deal found 4/28$249
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/211:45 pmPHX - BUF
1 stop6h 56mAmerican Airlines
Tue 6/101:48 pmBUF - PHX
1 stop7h 08mAmerican Airlines
Deal found 4/29$250
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/111:38 pmPHX - BUF
1 stop7h 21mDelta
Sun 7/136:30 amBUF - PHX
1 stop5h 57mDelta
Deal found 4/28$257
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/316:45 amPHX - BUF
1 stop6h 50mSouthwest
Sat 11/17:00 amBUF - PHX
2 stops12h 10mSouthwest
Deal found 4/29$260
This Mytrip deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/75:44 pmPHX - BUF
1 stop14h 00mMultiple Airlines
Thu 6/1211:47 amBUF - PHX
2 stops35h 18mMultiple Airlines
Deal found 4/28$315
This JetBlue deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/139:43 pmPHX - BUF
1 stop9h 00mJetBlue
Wed 7/1612:29 pmBUF - PHX
1 stop11h 05mJetBlue
Deal found 4/29$340
This Alaska Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/139:00 amPHX - BUF
2 stops11h 22mAlaska Airlines
Wed 7/165:05 amBUF - PHX
2 stops12h 42mAlaska Airlines
Deal found 4/29$550

Cheapflights Fare Finder

Customize your flight search to find flights from Mesa to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
Use the filters below to find and compare flights from Mesa to Buffalo that are best for you.

Fly from

Mesa

Fly to

Buffalo

Route

Depart

Return

Price

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Sat 5/17

3:11 pm-9:01 am

1 stop14h 50m

Buffalo

Sat 5/24

1:08 pm-4:27 pm

1 stop30h 19m

$201

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Sat 6/7

11:20 pm-9:56 am

1 stop7h 36m

Buffalo

Fri 6/13

6:15 am-10:20 am

1 stop7h 05m

$249

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Mon 6/2

11:45 pm-9:41 am

1 stop6h 56m

Buffalo

Tue 6/10

1:48 pm-5:56 pm

1 stop7h 08m

$250

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Fri 7/11

1:38 pm-11:59 pm

1 stop7h 21m

Buffalo

Sun 7/13

6:30 am-9:27 am

1 stop5h 57m

$257

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Tue 7/8

9:50 pm-7:45 am

1 stop6h 55m

Buffalo

Tue 7/15

7:10 pm-8:45 pm

Nonstop4h 35m

$301

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Sat 6/7

5:44 pm-10:44 am

1 stop14h 00m

Buffalo

Thu 6/12

11:47 am-8:05 pm

2 stops35h 18m

$315

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Tue 5/13

9:43 pm-9:43 am

1 stop9h 00m

Buffalo

Wed 7/16

12:29 pm-8:34 pm

1 stop11h 05m

$340

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Tue 5/13

9:00 am-11:22 pm

2 stops11h 22m

Buffalo

Wed 7/16

5:05 am-2:47 pm

2 stops12h 42m

$550

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Sat 5/10

3:11 pm-9:01 am

1 stop14h 50m

$105

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Mon 6/16

9:50 pm-9:00 am

1 stop8h 10m

$125

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/28

Showing 1-10 of 16 results
1
2

Best time to book a flight from Mesa to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Mesa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mesa to Buffalo

How far ahead should I book a flight from Mesa to Buffalo?

Use this chart to determine the optimal time to book a round-trip flight from Mesa to Buffalo. Price data was last updated on April 25, 2025.

Booking 72 days in advance of your planned departure date is, on average, the best time to get cheap flights from Mesa to Buffalo. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Mesa to Buffalo?

Currently, January is the cheapest month in which you can book a flight from Mesa to Buffalo (average of $256). Flying from Mesa to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS9 to BUF?

Find hourly flight availability from Mesa to Buffalo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 30, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mesa to Buffalo as you normally would.

What is the cheapest day to fly from Mesa to Buffalo?

Use this chart to determine the cheapest time to fly round-trip from Mesa to Buffalo. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Mesa to Buffalo flight should consider departing on Sunday evenings when fares are most often at their lowest. Saturday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Buffalo by month

Plan your trip to Buffalo by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Buffalo ranges from 2.5 - 4.0 inches per month. November is typically the wettest month, when rainfall can reach 4.0 in. February is typically the driest time to visit Buffalo when rainfall is around 2.5 in.

Temperature in Buffalo by month

Plan your trip to Buffalo by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Buffalo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 24.8 F).

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated April 30, 2025.
Peruse reviews from past customers who have flown with Alaska Airlines, Southwest and Delta from Mesa to Buffalo to help guide your decision. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
9,961 reviews

Entertainment

7.1

Boarding

8.2

Comfort

7.9

Food

7.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
9,961 reviews
Alaska Airlines
8.0
Very good
9,961 reviews

Entertainment

7.1

Boarding

8.2

Comfort

7.9

Food

7.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Southwest
8.0
Very good
4,295 reviews
Alaska Airlines
8.0
Very good
9,961 reviews

Entertainment

7.1

Boarding

8.2

Comfort

7.9

Food

7.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,936 reviews
Alaska Airlines
8.0
Very good
9,961 reviews

Entertainment

7.1

Boarding

8.2

Comfort

7.9

Food

7.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,696 reviews
Alaska Airlines
8.0
Very good
9,961 reviews

Entertainment

7.1

Boarding

8.2

Comfort

7.9

Food

7.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
JetBlue
7.3
Good
2,922 reviews
Alaska Airlines
8.0
Very good
9,961 reviews

Entertainment

7.1

Boarding

8.2

Comfort

7.9

Food

7.1

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from Mesa to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Buffalo from Mesa?

    If you book a flight to Buffalo from Mesa, you will be flying to Buffalo, which is the city’s only airport. Buffalo (BUF) is located 8.3 mi from the center of Buffalo. There are 0 flights from Mesa to Buffalo per day from 6 different airlines.

  • What are the cheapest airlines to fly from Mesa to Buffalo one-way?

    One-way options have recently been found by users for as low as $105 on Frontier. Other airlines that offer cheap prices include JetBlue from $125 and Delta from $129 one-way.

  • What are the cheapest flights from Mesa to Buffalo?

    On average you can expect to pay $369 for a flight from Mesa to Buffalo. The cheapest flight overall is $198 while the most popular route, (Phoenix Sky Harbor Intl - Buffalo) is currently priced at $249.

  • Can I find deals for flights from Mesa to Buffalo that include hotel bookings?

    Yes. In addition to deals on Mesa to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mesa to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mesa to Buffalo.

  • Can I find deals for business class flights from Mesa to Buffalo?

    Yes. Cheapflights offers flight deals from Mesa to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mesa to Buffalo?

    Currently, January is the cheapest month in which you can book a flight from Mesa to Buffalo (average of $256). Flying from Mesa to Buffalo in December is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Mesa?

Book flights to Mesa if you plan to visit one of these locations
Williamsville
Amherst
West Seneca
Batavia
Orchard Park
Cheektowaga

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Top 6 airlines flying from Mesa to Buffalo

Discover the top 6 airlines that operate flights from Mesa to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$124Average$306FlexibilityNo cancel feeOn-time62%
FrontierCheapest$161Average$255FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$166Average$318FlexibilityNo cancel feeOn-time71%
DeltaCheapest$236Average$322FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$248Average$358FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$313Average$497FlexibilityNo cancel feeOn-time63%

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