HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Buffalo

$97+ Cheap flights from Mesa, AZ to Buffalo (BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/15. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — BUF
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Mesa to Buffalo with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Mesa to Buffalo are usually found in June or April, booked 25 days in advance, depart on a Friday or Tuesday and return on a Tuesday

Cheap flight deals from Mesa to Buffalo

Cheapest flights from Mesa to Buffalo
Explore the most affordable flight options available from Mesa to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/231:15 pmPHX - BUF
1 stop7h 18mAmerican Airlines
Tue 1/68:00 amBUF - PHX
1 stop8h 09mAmerican Airlines
Deal found 12/16$349
This JetBlue deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3110:28 pmPHX - BUF
1 stop9h 51mJetBlue
Sat 1/311:04 amBUF - PHX
1 stop12h 04mJetBlue
Deal found 12/17$383
This Frontier deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:00 amPHX - BUF
1 stop10h 10mFrontier
Mon 12/2210:43 amBUF - PHX
1 stop15h 06mFrontier
Deal found 12/17$384
This Frontier deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:00 amPHX - BUF
1 stop8h 45mFrontier
Wed 12/3111:08 amBUF - PHX
1 stop14h 41mFrontier
Deal found 12/17$387
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:15 amPHX - BUF
2 stops13h 18mDelta
Fri 1/212:01 pmBUF - PHX
1 stop9h 09mDelta
Deal found 12/17$398
This Frontier deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/196:00 amPHX - BUF
1 stop8h 45mFrontier
Mon 12/2210:43 amBUF - PHX
1 stop15h 06mFrontier
Deal found 12/17$412
This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/304:02 pmPHX - BUF
1 stop5h 26mDelta
Fri 1/212:01 pmBUF - PHX
1 stop9h 09mDelta
Deal found 12/17$417
This United Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1610:10 amPHX - BUF
2 stops11h 24mUnited Airlines
Thu 1/12:50 pmBUF - PHX
1 stop8h 02mUnited Airlines
Deal found 12/15$422
This Booking.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2012:59 amPHX - BUF
1 stop9h 37mFrontier
Wed 12/2411:08 amBUF - PHX
1 stop14h 41mFrontier
Deal found 12/17$429
This JetBlue deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2710:28 pmPHX - BUF
1 stop9h 51mJetBlue
Fri 1/211:04 amBUF - PHX
1 stop12h 04mJetBlue
Deal found 12/17$432
This Booking.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:00 amPHX - BUF
1 stop10h 10mFrontier
Wed 12/3111:08 amBUF - PHX
1 stop14h 41mFrontier
Deal found 12/17$433
This Frontier deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:00 amPHX - BUF
1 stop10h 10mFrontier
Thu 12/252:07 pmBUF - PHX
1 stop11h 42mFrontier
Deal found 12/17$434

Find flight deals from Mesa to Buffalo

Keep the following information in mind while searching for Mesa to Buffalo flight deals. Data was last updated December 18, 2025.

Round-trip from

$234
(Kiwi.com)

One-way from

$97
(Priceline)

Popular in

January

Cheapest in

June

Average price

$433
From Mesa to Buffalo
Search Deals
One-way flight from Mesa to Buffalo
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($49 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mesa to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Mesa to Buffalo that are best for you.

Fly from

Mesa

Fly to

Buffalo

Route

Depart

Return

Price

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Mon 5/11

10:55 pm-8:23 am

1 stop6h 28m

Buffalo

Sat 5/16

4:57 pm-11:02 pm

1 stop9h 05m

$247

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Fri 1/9

2:09 pm-11:33 pm

1 stop7h 24m

Buffalo

Mon 1/12

12:58 pm-6:54 pm

1 stop7h 56m

$247

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Tue 2/24

11:59 pm-9:28 am

1 stop7h 29m

Buffalo

Tue 3/3

6:00 am-3:41 pm

1 stop11h 41m

$247

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Wed 5/6

12:00 pm-10:45 pm

1 stop7h 45m

Buffalo

Tue 5/12

2:44 pm-7:44 pm

1 stop8h 00m

$247

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Mon 1/12

11:40 pm-8:05 am

1 stop6h 25m

Buffalo

Mon 1/19

5:50 am-12:00 pm

1 stop8h 10m

$247

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Tue 5/12

10:55 pm-8:23 am

1 stop6h 28m

Buffalo

Wed 5/20

4:57 pm-11:02 pm

1 stop9h 05m

$247

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Sat 2/14

11:59 pm-9:28 am

1 stop7h 29m

Buffalo

Wed 2/18

3:00 pm-9:47 pm

1 stop8h 47m

$247

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Tue 1/13

10:22 am-8:29 pm

1 stop8h 07m

Buffalo

Tue 1/20

10:45 am-3:57 pm

1 stop7h 12m

$247

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Wed 1/28

11:35 am-10:00 pm

1 stop8h 25m

Buffalo

Fri 1/30

1:20 pm-7:40 pm

1 stop8h 20m

$247

PhoenixBuffalo

PHX - BUF

PHXBUF

Phoenix Sky Harbor Intl

Tue 5/5

10:55 pm-8:23 am

1 stop6h 28m

Buffalo

Tue 5/12

4:57 pm-11:02 pm

1 stop9h 05m

$247

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 20 results
1
2

Best time to book a flight from Mesa to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Mesa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mesa to Buffalo

How far ahead should I book a flight from Mesa to Buffalo?

Use this chart to determine the optimal time to book a round-trip flight from Mesa to Buffalo. Price data was last updated on December 12, 2025.

Booking 25 days in advance of your planned departure date is, on average, the best time to get cheap flights from Mesa to Buffalo. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Mesa to Buffalo?

Currently, July is the cheapest month in which you can book a flight from Mesa to Buffalo (average of $138). Flying from Mesa to Buffalo in October is currently the most expensive (average of $268). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS9 to BUF?

Find hourly flight availability from Mesa to Buffalo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

One of the essential ways to save on airfare from Mesa to Buffalo is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 53% on airfare.

What is the cheapest day to fly from Mesa to Buffalo?

Use this chart to determine the cheapest time to fly round-trip from Mesa to Buffalo. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Mesa to Buffalo flight should consider departing on Saturday mornings when fares are most often at their lowest. Friday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated December 18, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Mesa to Buffalo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
7.9
Good
4,250 reviews

Crew

8.6

Food

7.0

Overall

7.9

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
7.9
Good
4,250 reviews
Southwest
7.9
Good
4,250 reviews

Crew

8.6

Food

7.0

Overall

7.9

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Delta
7.9
Good
8,005 reviews
Southwest
7.9
Good
4,250 reviews

Crew

8.6

Food

7.0

Overall

7.9

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
United Airlines
7.4
Good
9,091 reviews
Southwest
7.9
Good
4,250 reviews

Crew

8.6

Food

7.0

Overall

7.9

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
American Airlines
7.2
Good
11,054 reviews
Southwest
7.9
Good
4,250 reviews

Crew

8.6

Food

7.0

Overall

7.9

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Frontier
5.8
Fair
3,081 reviews
Southwest
7.9
Good
4,250 reviews

Crew

8.6

Food

7.0

Overall

7.9

Comfort

8.0

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Mesa to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Buffalo from Mesa?

    If you book a flight to Buffalo from Mesa, you will be flying to Buffalo, which is the city’s only airport. Buffalo (BUF) is located 8.3 mi from the center of Buffalo. There are 0 flights from Mesa to Buffalo per day from 6 different airlines.

  • How long is the flight from Mesa to Buffalo?

    There are many flights that can get you from Mesa to Buffalo in 6h 28m. Fly via Delta, American Airlines, or JetBlue to get the fastest option. The distance from Mesa to Buffalo is about 1906 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Mesa to Buffalo one-way?

    One-way options have recently been found by users for as low as $117 on Frontier. Other airlines that offer cheap prices include JetBlue from $123 and American Airlines from $124 one-way.

  • Can I find deals for flights from Mesa to Buffalo that include hotel bookings?

    Yes. In addition to deals on Mesa to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mesa to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mesa to Buffalo.

  • Can I find deals for business class flights from Mesa to Buffalo?

    Yes. Cheapflights offers flight deals from Mesa to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mesa to Buffalo?

    Currently, July is the cheapest month in which you can book a flight from Mesa to Buffalo (average of $138). Flying from Mesa to Buffalo in October is currently the most expensive (average of $268). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Lockport
Cheektowaga
Batavia
Williamsville
Orchard Park
Eden
Amherst
West Seneca

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Mesa to Buffalo

See prices for flight routes from nearby airports that may be better suited for you.
Sky Harbor Intl to John F Kennedy Intl flights
Sky Harbor Intl to Newark flights
Las Vegas to John F Kennedy Intl flights
Sky Harbor Intl to LaGuardia flights
Las Vegas to Newark flights
Las Vegas to LaGuardia flights
Tucson to Newark flights
Tucson to John F Kennedy Intl flights
Tucson to LaGuardia flights
Sky Harbor Intl to Syracuse flights
Las Vegas to Buffalo flights
Las Vegas to Rochester flights
Sky Harbor Intl to Buffalo flights
Sky Harbor Intl to Albany flights
Las Vegas to Albany flights
Sky Harbor Intl to White Plains flights
Las Vegas to Syracuse flights
Sky Harbor Intl to Rochester flights
Las Vegas to Islip flights
Sky Harbor Intl to Islip flights
Tucson to White Plains flights
Tucson to Buffalo flights
Tucson to Syracuse flights
Sky Harbor Intl to Ithaca flights
Tucson to Albany flights
Tucson to Rochester flights
Las Vegas to White Plains flights
Sky Harbor Intl to Binghamton flights
Las Vegas to Stewart flights
Yuma to John F Kennedy Intl flights
Las Vegas to Ithaca flights
Yuma to LaGuardia flights
Yuma to Newark flights
Tucson to Ithaca flights
Las Vegas to Rutland flights
Sky Harbor Intl to Rutland flights
Flagstaff to LaGuardia flights
Tucson to Elmira flights
Yuma to Albany flights
Flagstaff to Newark flights
Las Vegas to Elmira flights
Las Vegas to Binghamton flights
Tucson to Binghamton flights
Sky Harbor Intl to Elmira flights
Sky Harbor Intl to Watertown flights
Las Vegas to Niagara Falls flights
Las Vegas to Watertown flights
Flagstaff to Syracuse flights

Top 6 airlines flying from Mesa to Buffalo

Discover the top 6 airlines that operate flights from Mesa to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$151Average$296FlexibilityNo cancel feeOn-time62%
JetBlueCheapest$198Average$338FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$248Average$338FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$248Average$381FlexibilityNo cancel feeOn-time71%
DeltaCheapest$256Average$338FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$313Average$483FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.