$74+ Cheap flights from Mesa, AZ to Buffalo (BUF)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/28. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — BUF
Mar 9 — Mar 161
1 adult, Economy
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Find cheap flights from Mesa to Buffalo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Mesa to Buffalo are usually found in June or August, booked 25 days in advance, depart on a Friday or Tuesday and return on a Thursday
Cheap flight deals from Mesa to Buffalo
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Best
Last-minute
One-way
Cheapest flights from Mesa to BuffaloExplore the most affordable flight options available from Mesa to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 7, 2026.
Explore the most affordable flight options available from Mesa to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 7, 2026.
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/911:50 pm
PHX
- BUF
1 stop9h 24m
American Airlines
Wed 3/185:30 am
BUF
- PHX
1 stop8h 37m
American Airlines
Deal found 2/3![American Airlines logo]()
$197
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/31:01 am
PHX
- BUF
1 stop9h 13m
American Airlines
Fri 3/67:45 pm
BUF
- PHX
1 stop7h 22m
American Airlines
Deal found 2/4![American Airlines logo]()
$201
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1812:17 am
PHX
- BUF
1 stop8h 36m
American Airlines
Mon 2/2311:23 am
BUF
- PHX
1 stop9h 57m
American Airlines
Deal found 2/4![American Airlines logo]()
$205
This Orbitz deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1012:30 am
PHX
- BUF
1 stop15h 43m
Frontier
Thu 5/141:08 pm
BUF
- PHX
1 stop11h 15m
Frontier
Deal found 2/4![Frontier logo]()
$211
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:00 am
PHX
- BUF
1 stop9h 54m
American Airlines
Wed 3/117:40 pm
BUF
- PHX
1 stop7h 27m
American Airlines
Deal found 2/4![American Airlines logo]()
$237
This Southwest deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/911:55 pm
PHX
- BUF
1 stop7h 15m
Southwest
Mon 3/163:55 pm
BUF
- PHX
1 stop7h 10m
Southwest
Deal found 2/6![Southwest logo]()
$245
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/49:45 am
PHX
- BUF
2 stops11h 07m
United Airlines
Tue 8/116:00 am
BUF
- PHX
1 stop7h 56m
United Airlines
Deal found 2/4![United Airlines logo]()
$250
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/712:55 am
PHX
- BUF
1 stop9h 13m
American Airlines
Fri 2/206:01 pm
BUF
- PHX
1 stop8h 03m
American Airlines
Deal found 2/4![American Airlines logo]()
$257
This American Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/1311:24 am
PHX
- BUF
1 stop9h 25m
American Airlines
Tue 2/176:39 pm
BUF
- PHX
1 stop8h 28m
American Airlines
Deal found 2/5![American Airlines logo]()
$277
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/610:55 pm
PHX
- BUF
1 stop6h 28m
Delta
Sun 7/127:35 pm
BUF
- PHX
1 stop6h 21m
Delta
Deal found 2/3![Delta logo]()
$278
This United Airlines deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/410:08 am
PHX
- BUF
2 stops10h 08m
United Airlines
Fri 8/75:47 pm
BUF
- PHX
1 stop8h 30m
United Airlines
Deal found 2/6![United Airlines logo]()
$283
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/247:07 am
PHX
- BUF
1 stop6h 33m
United Airlines
Tue 6/305:47 pm
BUF
- PHX
1 stop6h 55m
United Airlines
Deal found 2/4![United Airlines logo]()
$285
Best flights from Mesa to BuffaloDiscover carefully curated flight deals from Mesa to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 7, 2026.
Discover carefully curated flight deals from Mesa to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 7, 2026.
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/31:01 am
PHX
- BUF
1 stop9h 13m
American Airlines
Fri 3/67:45 pm
BUF
- PHX
1 stop7h 22m
American Airlines
Deal found 2/4![American Airlines logo]()
$201
This Delta deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/611:55 pm
PHX
- BUF
1 stop8h 06m
Delta
Sat 4/116:08 pm
BUF
- PHX
1 stop7h 41m
Delta
Deal found 2/5![Delta logo]()
$237
This Southwest deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1010:30 pm
PHX
- BUF
1 stop6h 20m
Southwest
Thu 5/148:00 pm
BUF
- PHX
1 stop6h 30m
Southwest
Deal found 2/4![Southwest logo]()
$245
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1010:08 am
PHX
- BUF
2 stops10h 08m
United Airlines
Sat 7/185:47 pm
BUF
- PHX
1 stop8h 30m
United Airlines
Deal found 2/4![United Airlines logo]()
$307
This Delta deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2110:55 pm
PHX
- BUF
1 stop6h 28m
Delta
Fri 7/247:35 pm
BUF
- PHX
1 stop6h 21m
Delta
Deal found 2/5![Delta logo]()
$237
This American Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/47:30 am
PHX
- BUF
1 stop8h 24m
American Airlines
Wed 3/117:40 pm
BUF
- PHX
1 stop7h 27m
American Airlines
Deal found 2/7![American Airlines logo]()
$237
This Southwest deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/3111:55 pm
PHX
- BUF
1 stop7h 20m
Southwest
Wed 6/36:40 am
BUF
- PHX
1 stop9h 15m
Southwest
Deal found 2/7![Southwest logo]()
$245
This Delta deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1810:55 pm
PHX
- BUF
1 stop6h 28m
Delta
Tue 7/217:35 pm
BUF
- PHX
1 stop6h 21m
Delta
Deal found 2/5![Delta logo]()
$237
This Southwest deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1211:55 pm
PHX
- BUF
1 stop7h 35m
Southwest
Tue 3/171:20 pm
BUF
- PHX
2 stops10h 10m
Southwest
Deal found 2/6![Southwest logo]()
$250
This Delta deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1810:55 pm
PHX
- BUF
1 stop6h 28m
Delta
Wed 7/224:30 pm
BUF
- PHX
1 stop9h 32m
Delta
Deal found 2/5![Delta logo]()
$237
This Delta deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/1810:55 pm
PHX
- BUF
1 stop6h 28m
Delta
Fri 7/247:35 pm
BUF
- PHX
1 stop6h 21m
Delta
Deal found 2/5![Delta logo]()
$237
This Delta deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2110:55 pm
PHX
- BUF
1 stop6h 28m
Delta
Wed 7/224:30 pm
BUF
- PHX
1 stop9h 32m
Delta
Deal found 2/5![Delta logo]()
$237
Last-minute flights from Mesa to BuffaloDiscover last-minute flight deals from Mesa to Buffalo. Data last updated February 7, 2026 and is based on user searches.
Discover last-minute flight deals from Mesa to Buffalo. Data last updated February 7, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/712:55 am
PHX
- BUF
1 stop9h 13m
American Airlines
Fri 2/206:01 pm
BUF
- PHX
1 stop8h 03m
American Airlines
Deal found 2/4![American Airlines logo]()
$257
This American Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/1311:24 am
PHX
- BUF
1 stop9h 25m
American Airlines
Tue 2/176:39 pm
BUF
- PHX
1 stop8h 28m
American Airlines
Deal found 2/5![American Airlines logo]()
$277
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1812:17 am
PHX
- BUF
1 stop8h 36m
American Airlines
Mon 2/2311:23 am
BUF
- PHX
1 stop9h 57m
American Airlines
Deal found 2/4![American Airlines logo]()
$205
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1912:17 am
PHX
- BUF
1 stop8h 41m
American Airlines
Mon 2/237:41 pm
BUF
- PHX
1 stop7h 26m
American Airlines
Deal found 2/3![American Airlines logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/263:10 pm
PHX
- BUF
1 stop19h 34m
Frontier
Mon 3/21:48 pm
BUF
- PHX
2 stops36h 11m
Frontier
Deal found 2/6![Frontier logo]()
$309
This American Airlines deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/21:01 am
PHX
- BUF
1 stop9h 13m
American Airlines
Wed 3/117:40 pm
BUF
- PHX
1 stop7h 27m
American Airlines
Deal found 2/5![American Airlines logo]()
$237
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/31:01 am
PHX
- BUF
1 stop9h 13m
American Airlines
Fri 3/67:45 pm
BUF
- PHX
1 stop7h 22m
American Airlines
Deal found 2/4![American Airlines logo]()
$201
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/312:51 am
PHX
- BUF
1 stop8h 52m
American Airlines
Wed 3/115:30 am
BUF
- PHX
1 stop8h 37m
American Airlines
Deal found 2/4![American Airlines logo]()
$292
This Southwest deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/46:00 am
PHX
- BUF
2 stops9h 05m
Southwest
Fri 3/67:35 pm
BUF
- PHX
1 stop6h 50m
Southwest
Deal found 2/4![Southwest logo]()
$317
This Southwest deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/52:30 pm
PHX
- BUF
1 stop7h 40m
Southwest
Thu 3/125:55 pm
BUF
- PHX
1 stop9h 10m
Southwest
Deal found 2/5![Southwest logo]()
$312
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/911:50 pm
PHX
- BUF
1 stop9h 24m
American Airlines
Wed 3/185:30 am
BUF
- PHX
1 stop8h 37m
American Airlines
Deal found 2/3![American Airlines logo]()
$197
This Southwest deal was found by Cheapflights users on 2/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/911:55 pm
PHX
- BUF
1 stop7h 15m
Southwest
Mon 3/163:55 pm
BUF
- PHX
1 stop7h 10m
Southwest
Deal found 2/6![Southwest logo]()
$245
One-way flights from Mesa to BuffaloSearch for one-way flight options from Mesa to Buffalo. Find affordable one-way fares based on user searches. Data last updated February 7, 2026.
Search for one-way flight options from Mesa to Buffalo. Find affordable one-way fares based on user searches. Data last updated February 7, 2026.
This Frontier deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2811:59 pm
PHX
- BUF
1 stop7h 53m
Frontier
Deal found 2/3![Frontier logo]()
$74
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2211:59 pm
PHX
- BUF
1 stop7h 51m
American Airlines
Deal found 2/4![American Airlines logo]()
$99
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1811:51 pm
PHX
- BUF
1 stop8h 58m
American Airlines
Deal found 2/4![American Airlines logo]()
$100
This Frontier deal was found by Cheapflights users on 2/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2710:30 pm
PHX
- BUF
1 stop10h 43m
Frontier
Deal found 2/5![Frontier logo]()
$101
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1812:17 am
PHX
- BUF
1 stop8h 36m
American Airlines
Deal found 2/3![American Airlines logo]()
$103
This Frontier deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/511:59 pm
PHX
- BUF
1 stop8h 50m
Frontier
Deal found 2/3![Frontier logo]()
$109
This Frontier deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/411:59 pm
PHX
- BUF
1 stop9h 40m
Frontier
Deal found 2/4![Frontier logo]()
$116
This American Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3111:35 pm
PHX
- BUF
1 stop8h 23m
American Airlines
Deal found 2/4![American Airlines logo]()
$118
This Delta deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/211:05 pm
PHX
- BUF
1 stop6h 11m
Delta
Deal found 2/4![Delta logo]()
$119
This United Airlines deal was found by Cheapflights users on 2/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/311:47 pm
PHX
- BUF
1 stop7h 06m
United Airlines
Deal found 2/4![United Airlines logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/610:24 pm
PHX
- BUF
2 stops34h 41m
Frontier
Deal found 2/3![Frontier logo]()
$126
Find flight deals from Mesa to Buffalo
Keep the following information in mind while searching for Mesa to Buffalo flight deals. Data was last updated February 7, 2026.
Round-trip from | $197 (American Airlines) |
|---|---|
One-way from | $74 (Frontier) |
Popular in | January |
Cheapest in | June |
Average price | $459 |
Cheapflights Fare Finder
Customize your flight search to find flights from Mesa to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 7, 2026.
Use the filters below to find and compare flights from Mesa to Buffalo that are best for you.
Fly from
Mesa
Fly to
Buffalo
Route
Depart
Return
Price
PhoenixBuffalo
PHX - BUF
PHXBUF
Phoenix Sky Harbor Intl
Tue 3/3
1:01 am-12:14 pm
1 stop9h 13m
Buffalo
Fri 3/6
7:45 pm-1:07 am
1 stop7h 22m
$201
PhoenixBuffalo
PHX - BUF
PHXBUF
Phoenix Sky Harbor Intl
Mon 4/6
11:55 pm-11:01 am
1 stop8h 06m
Buffalo
Sat 4/11
6:08 pm-10:49 pm
1 stop7h 41m
$237
PhoenixBuffalo
PHX - BUF
PHXBUF
Phoenix Sky Harbor Intl
Tue 7/21
10:55 pm-8:23 am
1 stop6h 28m
Buffalo
Fri 7/24
7:35 pm-10:56 pm
1 stop6h 21m
$237
PhoenixBuffalo
PHX - BUF
PHXBUF
Phoenix Sky Harbor Intl
Wed 3/4
7:30 am-5:54 pm
1 stop8h 24m
Buffalo
Wed 3/11
7:40 pm-12:07 am
1 stop7h 27m
$237
PhoenixBuffalo
PHX - BUF
PHXBUF
Phoenix Sky Harbor Intl
Sat 7/18
10:55 pm-8:23 am
1 stop6h 28m
Buffalo
Tue 7/21
7:35 pm-10:56 pm
1 stop6h 21m
$237
PhoenixBuffalo
PHX - BUF
PHXBUF
Phoenix Sky Harbor Intl
Sat 7/18
10:55 pm-8:23 am
1 stop6h 28m
Buffalo
Wed 7/22
4:30 pm-11:02 pm
1 stop9h 32m
$237
PhoenixBuffalo
PHX - BUF
PHXBUF
Phoenix Sky Harbor Intl
Sat 7/18
10:55 pm-8:23 am
1 stop6h 28m
Buffalo
Fri 7/24
7:35 pm-10:56 pm
1 stop6h 21m
$237
PhoenixBuffalo
PHX - BUF
PHXBUF
Phoenix Sky Harbor Intl
Tue 7/21
10:55 pm-8:23 am
1 stop6h 28m
Buffalo
Wed 7/22
4:30 pm-11:02 pm
1 stop9h 32m
$237
PhoenixBuffalo
PHX - BUF
PHXBUF
Phoenix Sky Harbor Intl
Sun 5/10
10:30 pm-7:50 am
1 stop6h 20m
Buffalo
Thu 5/14
8:00 pm-11:30 pm
1 stop6h 30m
$245
PhoenixBuffalo
PHX - BUF
PHXBUF
Phoenix Sky Harbor Intl
Sun 5/31
11:55 pm-10:15 am
1 stop7h 20m
Buffalo
Wed 6/3
6:40 am-12:55 pm
1 stop9h 15m
$245
Showing 1-10 of 22 results
Best time to book a flight from Mesa to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Mesa with our price prediction graph.
PHX-BUF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mesa to Buffalo
MS9-BUF
PHX-BUF
How far ahead should I book a flight from Mesa to Buffalo?
Use this chart to determine the optimal time to book a round-trip flight from Mesa to Buffalo. Price data was last updated on January 30, 2026.
Booking 25 days in advance of your planned departure date is, on average, the best time to get cheap flights from Mesa to Buffalo. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Mesa to Buffalo?
Currently, July is the cheapest month in which you can book a flight from Mesa to Buffalo (average of $138). Flying from Mesa to Buffalo in December is currently the most expensive (average of $297). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MS9 to BUF?
Find hourly flight availability from Mesa to Buffalo. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 7, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Mesa to Buffalo as you normally would.
Reviews of airlines servicing Buffalo
Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated February 7, 2026.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Mesa to Buffalo to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Food
7.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Mesa to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsLockport
Cheektowaga
Batavia
Williamsville
Orchard Park
Eden
Amherst
West Seneca
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
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Alternative routes for Mesa to Buffalo
See prices for flight routes from nearby airports that may be better suited for you.
Other flights to Buffalo
Explore flights to Buffalo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on February 7, 2026.
Complete your trip
Complete your trip to Buffalo by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Mesa to Buffalo by cabin class
Find flights from Mesa to Buffalo, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Mesa and Buffalo flights
Browse other Mesa and Buffalo flight options. Last updated on February 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Mesa to Buffalo flights
Consider these flights traveling from Mesa to Buffalo.
Top 6 airlines flying from Mesa to Buffalo
Discover the top 6 airlines that operate flights from Mesa to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$91 | Average$293 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$246 | Average$338 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$248 | Average$362 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$248 | Average$391 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$268 | Average$338 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$273 | Average$475 | FlexibilityNo cancel fee | On-time63% |