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$382+ Cheap flights from Medford to Buffalo (MFR - BUF)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/21. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — BUF
May 28 — Jun 41
Thu 5/28
Thu 6/4
1 adult, Economy
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Cheap flight deals from Medford to Buffalo

Cheapest flights from Medford to Buffalo
Explore the most affordable flight options available from Medford to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.

This Alaska Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:35 pm
MFR
-
BUF
2 stops10h 57m
Alaska Airlines
Tue 7/215:08 am
BUF
-
MFR
2 stops13h 06m
Alaska Airlines
Deal found 4/23$618
This United Airlines deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/156:00 am
MFR
-
BUF
2 stops14h 59m
United Airlines
Tue 7/219:00 am
BUF
-
MFR
1 stop7h 05m
United Airlines
Deal found 4/24$792

Find flight deals from Medford to Buffalo

Discover tips and strategies to find the most affordable flight options for your journey from Medford (MFR) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$618
(Alaska Airlines)

One-way from

$382
(Delta)
Provider with most accurate pricing for Medford-Buffalo flight deals.
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Provider most trusted by Cheapflights users for Medford-Buffalo flights.
Search Deals
From Medford to Buffalo
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One-way flight from Medford to Buffalo
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Medford to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
Use the filters below to find and compare flights from Medford to Buffalo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MedfordBuffalo

MFR - BUF

MFRBUF

Medford

Wed 7/15

7:35 pm-9:32 am

2 stops10h 57m

Buffalo

Tue 7/21

5:08 am-3:14 pm

2 stops13h 06m

$618
Quickest round-trip

MedfordBuffalo

MFR - BUF

MFRBUF

Medford

Wed 7/15

6:00 am-11:59 pm

2 stops14h 59m

Buffalo

Tue 7/21

9:00 am-1:05 pm

1 stop7h 05m

$792
Cheapest one-way

MedfordBuffalo

MFR - BUF

MFRBUF

Medford

Tue 7/21

5:29 pm-9:41 am

2 stops13h 12m

$382

MedfordBuffalo

MFR - BUF

MFRBUF

Medford

Sun 5/3

9:12 pm-10:41 am

3 stops34h 29m

$413
Quickest one-way

MedfordBuffalo

MFR - BUF

MFRBUF

Medford

Tue 7/21

1:10 pm-10:58 pm

1 stop6h 48m

$428

MedfordBuffalo

MFR - BUF

MFRBUF

Medford

Sun 5/3

6:36 pm-9:41 am

2 stops12h 05m

$434

MedfordBuffalo

MFR - BUF

MFRBUF

Medford

Tue 7/21

10:31 am-11:11 am

3 stops21h 40m

$541

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/26

Sorted by cheapest first

Compare providers for flights from Medford to Buffalo

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Medford to Buffalo in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Medford-Buffalo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Medford-Buffalo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Medford-Buffalo flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Medford-Buffalo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Medford-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Medford to Buffalo

Have a flexible travel schedule? Discover the best time to fly to Buffalo from Medford with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Buffalo

Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated April 28, 2026.
See what other customers who have flown with United Airlines from Medford to Buffalo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,665 reviews

Overall

7.4

Comfort

7.3

Boarding

7.7

Entertainment

7.1

Crew

8.1

Food

6.6

Reviews

1 / 20
8.0
Excellent

Anonymous,Apr 2026

DFW - EWR

The flight was on time. Crew was friendly. Will fly again. The seats was comfortable.
United Airlines
7.4
Good
9,665 reviews
United Airlines
7.4
Good
9,665 reviews

Overall

7.4

Comfort

7.3

Boarding

7.7

Entertainment

7.1

Crew

8.1

Food

6.6

Reviews

1 / 20
8.0
Excellent

Anonymous,Apr 2026

DFW - EWR

The flight was on time. Crew was friendly. Will fly again. The seats was comfortable.

Related info for your journey

Find useful and relevant information for your journey from Medford to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Medford to Buffalo?

    For as low as $618, Alaska Airlines can have you in Buffalo from Medford in 10h 57m. There are 2216 mi between Medford and Buffalo.

  • What is the cheapest airline to fly from Medford to Buffalo round-trip?

    United Airlines, at $409, was found to be the cheapest airline from Medford to Buffalo..

  • Can I find deals for flights from Medford to Buffalo that include hotel bookings?

    Yes. In addition to deals on Medford to Buffalo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Medford to Buffalo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Medford to Buffalo.

  • Can I find deals for business class flights from Medford to Buffalo?

    Yes. Cheapflights offers flight deals from Medford to Buffalo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Buffalo?

Book flights to Buffalo if you plan to visit one of these locations
Lockport
Cheektowaga
Batavia
Williamsville
Orchard Park
Eden
Amherst
West Seneca

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Top airline flying from Medford to Buffalo

Discover the top airline that operate flights from Medford to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$409Average$563FlexibilityNo cancel feeOn-time69%

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