$303+ Cheap flights from Medford to Buffalo (MFR - BUF)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/1. Fares are subject to change and may not be available on all flights or dates of travel.
MFR — BUF
Oct 10 — Oct 171
Round-trip
1 adult, Economy
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Find cheap flights from Medford to Buffalo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Medford to Buffalo
Cheapest
Best
Last-minute
One-way
Cheapest flights from Medford to BuffaloExplore the most affordable flight options available from Medford to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
Explore the most affordable flight options available from Medford to Buffalo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
This American Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:04 am -
2 stops13h 42m
Sat 12/57:03 am -
2 stops12h 42m
Deal found 9/6![American Airlines logo]()
$419
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/251:01 pm -
1 stop6h 42m
Sat 10/31:48 pm -
2 stops10h 26m
Deal found 9/8![United Airlines logo]()
$525
This United Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/241:00 pm -
1 stop6h 33m
Sat 12/51:53 pm -
2 stops10h 17m
Deal found 9/6![United Airlines logo]()
$687
This Alaska Airlines deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:06 am -
2 stops14h 59m
Sat 12/511:26 am -
2 stops11h 33m
Deal found 9/6![Alaska Airlines logo]()
$708
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:28 pm -
2 stops12h 01m
Fri 10/167:59 pm -
2 stops18h 51m
Deal found 9/7![United Airlines logo]()
$729
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2412:22 pm -
2 stops8h 31m
Mon 9/2812:02 pm -
2 stops14h 15m
Deal found 9/8![Delta logo]()
$789
Best flights from Medford to BuffaloDiscover carefully curated flight deals from Medford to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
Discover carefully curated flight deals from Medford to Buffalo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/276:00 am -
2 stops13h 54m
Sat 1/3010:20 am -
2 stops12h 35m
Deal found 9/9![United Airlines logo]()
$495
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/251:01 pm -
1 stop6h 42m
Sat 10/31:48 pm -
2 stops10h 26m
Deal found 9/8![United Airlines logo]()
$525
Last-minute flights from Medford to BuffaloDiscover last-minute flight deals from Medford to Buffalo. Data last updated September 10, 2026 and is based on user searches.
Discover last-minute flight deals from Medford to Buffalo. Data last updated September 10, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2412:22 pm -
2 stops8h 31m
Mon 9/2812:02 pm -
2 stops14h 15m
Deal found 9/8![Delta logo]()
$789
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/251:01 pm -
1 stop6h 42m
Sat 10/31:48 pm -
2 stops10h 26m
Deal found 9/8![United Airlines logo]()
$525
This United Airlines deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:28 pm -
2 stops12h 01m
Fri 10/167:59 pm -
2 stops18h 51m
Deal found 9/7![United Airlines logo]()
$729
One-way flights from Medford to BuffaloSearch for one-way flight options from Medford to Buffalo. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
Search for one-way flight options from Medford to Buffalo. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
This Delta deal was found by Cheapflights users on 9/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:13 am -
2 stops9h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/7![Delta logo]()
$303
This Priceline deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:58 pm -
2 stops12h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Alaska Airlines logo]()
$439
This United Airlines deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/181:08 pm -
1 stop6h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![United Airlines logo]()
$444
This United Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/12:08 pm -
3 stops23h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![United Airlines logo]()
$448
This Kiwi.com deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/189:22 am -
3 stops24h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/5![Multiple Airlines logo]()
$524
Find flight deals from Medford to Buffalo
Discover tips and strategies to find the most affordable flight options for your journey from Medford (MFR) to Buffalo (BUF). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $419 (American Airlines) |
One-way from | $303 (Delta) |
Cheapflights Fare Finder
Customize your flight search to find flights from Medford to Buffalo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
Use the filters below to find and compare flights from Medford to Buffalo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MedfordBuffalo
MFR Medford - BUF Buffalo
MFRBUF
Medford
Thu 10/1
6:13 am-7:04 pm
2 stops9h 51m
Buffalo
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$303
Quickest round-trip
MedfordBuffalo
MFR Medford - BUF Buffalo
MFRBUF
Medford
Fri 9/18
1:08 pm-10:37 pm
1 stop6h 29m
Buffalo
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$444
MedfordBuffalo
MFR Medford - BUF Buffalo
MFRBUF
Medford
Thu 10/1
2:08 pm-4:43 pm
3 stops23h 35m
Buffalo
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$448
MedfordBuffalo
MFR Medford - BUF Buffalo
MFRBUF
Medford
Wed 1/27
6:00 am-10:54 pm
2 stops13h 54m
Buffalo
Sat 1/30
10:20 am-7:55 pm
2 stops12h 35m
$495
MedfordBuffalo
MFR Medford - BUF Buffalo
MFRBUF
Medford
Fri 9/25
1:01 pm-10:43 pm
1 stop6h 42m
Buffalo
Sat 10/3
1:48 pm-9:14 pm
2 stops10h 26m
$525
Sorted by cheapest first
Compare providers for flights from Medford to Buffalo
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Medford to Buffalo in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Medford-Buffalo flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Medford-Buffalo flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Medford-Buffalo flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Medford-Buffalo flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Medford-Buffalo flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Medford to Buffalo
Have a flexible travel schedule? Discover the best time to fly to Buffalo from Medford with our price prediction graph.
MFR-BUF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Buffalo
Get insights into the airlines that provide service to Buffalo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Buffalo. Reviews last updated September 10, 2026.
See what other customers who have flown with United Airlines from Medford to Buffalo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.1
Comfort
7.3
Food
6.6
Boarding
7.7
Overall
7.4
Crew
8.1
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Entertainment
7.1
Comfort
7.3
Food
6.6
Boarding
7.7
Overall
7.4
Crew
8.1
Reviews
1 / 20
4.0
OkayChris,Aug 2026
MIA - ORD
Related info for your journey
Find useful and relevant information for your journey from Medford to Buffalo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Buffalo?
Book flights to Buffalo if you plan to visit one of these locationsCheektowaga
Lockport
Amherst
Williamsville
Orchard Park
Eden
Bowmansville
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Other flights to Buffalo
Explore flights to Buffalo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 10, 2026.
Complete your trip
Complete your trip to Buffalo by adding a car rental and/or hotel reservation to your travel itinerary.
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Medford and Buffalo flights
Browse other Medford and Buffalo flight options. Last updated on September 10, 2026.
Other flights from Medford
Browse through other flights departing from Medford. Flights are based on user searches made on Cheapflights and were last updated on September 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Medford to Buffalo
Discover the top airline that operate flights from Medford to Buffalo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$348 | Average$513 | FlexibilityNo cancel fee | On-time69% |