$312+ Cheap flights from St. Louis (STL) to Brussels
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/13. Fares are subject to change and may not be available on all flights or dates of travel.
STL — BRU
Aug 27 — Sep 31
Round-trip
1 adult, Economy
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Find cheap flights from St. Louis to Brussels with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Brussels
Cheapest
Best
Last-minute
One-way
Cheapest flights from St. Louis to BrusselsExplore the most affordable flight options available from St. Louis to Brussels. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2026.
Explore the most affordable flight options available from St. Louis to Brussels. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2026.
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/294:05 pm
STL
- BRU
2 stops14h 10m
United Airlines
Wed 12/24:55 pm
BRU
- STL
2 stops32h 43m
United Airlines
Deal found 7/26![United Airlines logo]()
$773
This Finnair deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:18 pm
STL
- BRU
2 stops18h 02m
Multiple Airlines
Mon 10/57:05 pm
BRU
- STL
2 stops31h 43m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$831
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2512:10 pm
STL
- BRU
1 stop12h 00m
United Airlines
Wed 9/29:30 am
BRU
- STL
2 stops32h 47m
United Airlines
Deal found 7/24![United Airlines logo]()
$843
This Mytrip deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:55 am
STL
- BRU
2 stops15h 55m
Air Canada
Wed 9/29:55 am
BRU
- STL
2 stops15h 47m
Air Canada
Deal found 7/24![Air Canada logo]()
$861
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:30 am
STL
- BRU
2 stops16h 40m
United Airlines
Mon 10/52:25 pm
BRU
- STL
1 stop30h 00m
United Airlines
Deal found 7/26![United Airlines logo]()
$862
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/812:10 pm
STL
- BRU
1 stop12h 00m
United Airlines
Tue 9/159:10 am
BRU
- STL
2 stops33h 47m
United Airlines
Deal found 7/25![United Airlines logo]()
$899
This FlightHub deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2412:10 pm
STL
- BRU
2 stops24h 50m
Air Canada
Sat 9/59:30 am
BRU
- STL
2 stops33h 32m
Air Canada
Deal found 7/23![Air Canada logo]()
$900
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/249:30 am
STL
- BRU
2 stops20h 45m
United Airlines
Sat 9/59:30 am
BRU
- STL
2 stops31h 42m
United Airlines
Deal found 7/27![United Airlines logo]()
$901
This Mytrip deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/253:30 pm
STL
- CRL
2 stops19h 15m
Multiple Airlines
Wed 9/25:30 pm
CRL
- STL
3 stops32h 12m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$1,545
This Mytrip deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/412:10 pm
STL
- CRL
2 stops23h 40m
Multiple Airlines
Tue 8/118:30 pm
CRL
- STL
2 stops23h 55m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$1,828
This Mytrip deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/3012:10 pm
STL
- CRL
2 stops19h 00m
Multiple Airlines
Sat 8/18:15 pm
CRL
- STL
2 stops24h 10m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$2,604
Best flights from St. Louis to BrusselsDiscover carefully curated flight deals from St. Louis to Brussels that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 28, 2026.
Discover carefully curated flight deals from St. Louis to Brussels that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 28, 2026.
This United Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/295:00 am
STL
- BRU
1 stop20h 55m
United Airlines
Wed 12/24:55 pm
BRU
- STL
2 stops28h 35m
United Airlines
Deal found 7/26![United Airlines logo]()
$773
This Gotogate deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/218:55 am
STL
- BRU
2 stops15h 15m
Air Canada
Tue 9/299:10 am
BRU
- STL
2 stops18h 10m
Air Canada
Deal found 7/27![Air Canada logo]()
$773
This Finnair deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:18 pm
STL
- BRU
2 stops18h 02m
Multiple Airlines
Mon 10/57:05 pm
BRU
- STL
2 stops31h 43m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$831
This Mytrip deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/253:30 pm
STL
- CRL
2 stops19h 15m
Multiple Airlines
Wed 9/25:30 pm
CRL
- STL
3 stops32h 12m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$1,545
Last-minute flights from St. Louis to BrusselsDiscover last-minute flight deals from St. Louis to Brussels. Data last updated July 28, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Brussels. Data last updated July 28, 2026 and is based on user searches.
This Mytrip deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/3012:10 pm
STL
- CRL
2 stops19h 00m
Multiple Airlines
Sat 8/18:15 pm
CRL
- STL
2 stops24h 10m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$2,604
This Gotogate deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/48:55 am
STL
- BRU
2 stops15h 15m
Multiple Airlines
Tue 8/119:30 am
BRU
- STL
1 stop16h 12m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$1,119
This FlightHub deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/412:10 pm
STL
- BRU
1 stop12h 00m
Air Canada
Tue 8/119:30 am
BRU
- STL
2 stops35h 34m
Air Canada
Deal found 7/27![Air Canada logo]()
$1,141
This Mytrip deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/412:10 pm
STL
- CRL
2 stops23h 40m
Multiple Airlines
Tue 8/118:30 pm
CRL
- STL
2 stops23h 55m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$1,828
This FlightHub deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2412:10 pm
STL
- BRU
2 stops24h 50m
Air Canada
Sat 9/59:30 am
BRU
- STL
2 stops33h 32m
Air Canada
Deal found 7/23![Air Canada logo]()
$900
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/249:30 am
STL
- BRU
2 stops20h 45m
United Airlines
Sat 9/59:30 am
BRU
- STL
2 stops31h 42m
United Airlines
Deal found 7/27![United Airlines logo]()
$901
This FlightHub deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2412:10 pm
STL
- BRU
1 stop12h 00m
Multiple Airlines
Sat 9/59:30 am
BRU
- STL
1 stop16h 12m
Multiple Airlines
Deal found 7/26![Multiple Airlines logo]()
$917
This United Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2512:10 pm
STL
- BRU
1 stop12h 00m
United Airlines
Wed 9/29:30 am
BRU
- STL
2 stops32h 47m
United Airlines
Deal found 7/24![United Airlines logo]()
$843
This Mytrip deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:55 am
STL
- BRU
2 stops15h 55m
Air Canada
Wed 9/29:55 am
BRU
- STL
2 stops15h 47m
Air Canada
Deal found 7/24![Air Canada logo]()
$861
This Mytrip deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/253:30 pm
STL
- CRL
2 stops19h 15m
Multiple Airlines
Wed 9/25:30 pm
CRL
- STL
3 stops32h 12m
Multiple Airlines
Deal found 7/24![Multiple Airlines logo]()
$1,545
One-way flights from St. Louis to BrusselsSearch for one-way flight options from St. Louis to Brussels. Find affordable one-way fares based on user searches. Data last updated July 28, 2026.
Search for one-way flight options from St. Louis to Brussels. Find affordable one-way fares based on user searches. Data last updated July 28, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/138:10 pm
STL
- BRU
2 stops33h 45m
Multiple Airlines
Deal found 7/23![Multiple Airlines logo]()
$312
This Cheapflightsfares deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/139:35 pm
STL
- BRU
1 stop10h 40m
British Airways
Deal found 7/23![British Airways logo]()
$447
This FlightHub deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/35:58 pm
STL
- BRU
2 stops32h 42m
Aer Lingus
Deal found 7/25![Aer Lingus logo]()
$454
This Kiwi.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:17 pm
STL
- BRU
3 stops59h 38m
Multiple Airlines
Deal found 7/25![Multiple Airlines logo]()
$480
This United Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/137:30 am
STL
- BRU
3 stops19h 00m
United Airlines
Deal found 7/23![United Airlines logo]()
$483
This Kiwi.com deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/47:58 pm
STL
- CRL
3 stops42h 42m
Multiple Airlines
Deal found 7/25![Multiple Airlines logo]()
$488
This United Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/48:00 am
STL
- BRU
2 stops22h 15m
United Airlines
Deal found 7/25![United Airlines logo]()
$520
This TravelUp deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure TravelUp is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/412:59 pm
STL
- BRU
1 stop13h 01m
Lufthansa
Deal found 7/25![Lufthansa logo]()
$521
This FlightHub deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/99:40 pm
STL
- BRU
1 stop15h 20m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$607
This Justfly.com deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/37:51 pm
STL
- BRU
2 stops31h 04m
British Airways
Deal found 7/26![British Airways logo]()
$609
This United Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/312:10 pm
STL
- BRU
1 stop12h 00m
United Airlines
Deal found 7/27![United Airlines logo]()
$635
This Kiwi.com deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/98:08 pm
STL
- CRL
3 stops39h 32m
Multiple Airlines
Deal found 7/27![Multiple Airlines logo]()
$665
Find flight deals from St. Louis to Brussels
Discover tips and strategies to find the most affordable flight options for your journey from St. Louis (STL) to Brussels (BR1). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 28, 2026.
Round-trip from | $773 (United Airlines) |
|---|---|
One-way from | $312 (Kiwi.com) |
Popular in | December |
Cheapest in | February |
Average price | $1,206 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Brussels that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2026.
Use the filters below to find and compare flights from St. Louis to Brussels that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisBrussels
STL - BRU
STLBRU
Lambert-St Louis
Sun 11/29
5:00 am-8:55 am
1 stop20h 55m
Brussels Bruxelles-National
Wed 12/2
4:55 pm-2:30 pm
2 stops28h 35m
$773
Quickest round-trip
St. LouisBrussels
STL - BRU
STLBRU
Lambert-St Louis
Mon 9/21
8:55 am-7:10 am
2 stops15h 15m
Brussels Bruxelles-National
Tue 9/29
9:10 am-8:20 pm
2 stops18h 10m
$773
St. LouisBrussels
STL - BRU
STLBRU
Lambert-St Louis
Wed 9/30
5:18 pm-6:20 pm
2 stops18h 02m
Brussels Bruxelles-National
Mon 10/5
7:05 pm-7:48 pm
2 stops31h 43m
$831
St. LouisBrussels
STL - CRL
STLCRL
Lambert-St Louis
Tue 8/25
3:30 pm-5:45 pm
2 stops19h 15m
Charleroi Brussels
Wed 9/2
5:30 pm-6:42 pm
3 stops32h 12m
$1,545
Cheapest one-way
Quickest one-way
St. LouisBrussels
STL - BRU
STLBRU
Lambert-St Louis
Tue 10/13
9:35 pm-3:15 pm
1 stop10h 40m
$447
St. LouisBrussels
STL - BRU
STLBRU
Lambert-St Louis
Fri 9/4
6:17 pm-12:55 pm
3 stops59h 38m
$480
St. LouisBrussels
STL - CRL
STLCRL
Lambert-St Louis
Fri 9/4
7:58 pm-9:40 pm
3 stops42h 42m
$488
St. LouisBrussels
STL - BRU
STLBRU
Lambert-St Louis
Mon 8/3
8:55 am-9:40 am
2 stops17h 45m
$489
St. LouisBrussels
STL - BRU
STLBRU
Lambert-St Louis
Fri 9/4
8:00 am-1:15 pm
2 stops22h 15m
$520
St. LouisBrussels
STL - BRU
STLBRU
Lambert-St Louis
Sun 8/9
9:40 pm-8:00 pm
1 stop15h 20m
$607
Showing 1-10 of 13 resultsSorted by cheapest first
Best time to book a flight from St. Louis to Brussels
Have a flexible travel schedule? Discover the best time to fly to Brussels from St. Louis with our price prediction graph.
STL-BR1
STL-BRU
STL-CRL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Brussels
STL-BR1
STL-BRU
STL-CRL
What is the cheapest month to book a flight from St. Louis to Brussels?
Currently, February is the cheapest month in which you can book a flight from St. Louis to Brussels (average of $494). Flying from St. Louis to Brussels in December is currently the most expensive (average of $2,205). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Brussels
Get insights into the airlines that provide service to Brussels. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Brussels. Reviews last updated July 28, 2026.
Read through reviews of airlines operating flights from St. Louis to Brussels, such as United Airlines and Lufthansa. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
6.6
Comfort
7.3
Entertainment
7.1
Boarding
7.7
Overall
7.4
Crew
8.1
Reviews
1 / 20
6.0
GoodROHIT,Jun 2026
IND - EWR
Food
6.6
Comfort
7.3
Entertainment
7.1
Boarding
7.7
Overall
7.4
Crew
8.1
Reviews
1 / 20
6.0
GoodROHIT,Jun 2026
IND - EWR
Food
6.6
Comfort
7.3
Entertainment
7.1
Boarding
7.7
Overall
7.4
Crew
8.1
Reviews
1 / 20
6.0
GoodROHIT,Jun 2026
IND - EWR
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Brussels. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for St. Louis to Brussels
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Brussels by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from St. Louis to Brussels by cabin class
Find flights from St. Louis to Brussels, based on your preferred cabin class, be it economy, premium economy, business, or first class.
St. Louis and Brussels flights
Browse other St. Louis and Brussels flight options. Last updated on July 28, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on July 28, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from St. Louis to Brussels
Discover the top 2 airlines that operate flights from St. Louis to Brussels. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$441 | Average$1,282 | FlexibilityNo cancel fee | On-time76% | |
| Cheapest$507 | Average$981 | FlexibilityNo cancel fee | On-time69% |