$426+ Cheap flights from Des Moines (DSM) to Barcelona
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — BCN
Apr 26 — May 31
Round-trip
1 adult, Economy
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Find cheap flights from Des Moines to Barcelona with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Des Moines to Barcelona
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Best
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Cheapest flights from Des Moines to BarcelonaExplore the most affordable flight options available from Des Moines to Barcelona. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 27, 2026.
Explore the most affordable flight options available from Des Moines to Barcelona. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 27, 2026.
This United Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:15 am
DSM
- BCN
2 stops19h 45m
United Airlines
Fri 12/1110:30 am
BCN
- DSM
2 stops20h 09m
United Airlines
Deal found 3/23![United Airlines logo]()
$724
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/25:25 pm
DSM
- BCN
2 stops14h 25m
Delta
Tue 9/1511:00 am
BCN
- DSM
2 stops29h 19m
Delta
Deal found 3/24![Delta logo]()
$795
This Air France deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/25:25 pm
DSM
- BCN
2 stops14h 25m
Air France
Tue 9/1512:20 pm
BCN
- DSM
2 stops17h 06m
Air France
Deal found 3/23![Air France logo]()
$802
This KLM deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/64:23 pm
DSM
- BCN
2 stops16h 12m
Multiple Airlines
Wed 5/1311:00 am
BCN
- DSM
1 stop13h 53m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$816
This Flysmarter deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flysmarter is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/62:16 pm
DSM
- BCN
1 stop13h 19m
British Airways
Wed 5/1310:30 am
BCN
- DSM
1 stop20h 19m
British Airways
Deal found 3/24![British Airways logo]()
$819
This Expedia deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/612:00 pm
DSM
- BCN
1 stop15h 35m
Iberia
Wed 5/1310:30 am
BCN
- DSM
1 stop20h 19m
Iberia
Deal found 3/24![Iberia logo]()
$822
This British Airways deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:00 pm
DSM
- BCN
2 stops16h 45m
Multiple Airlines
Thu 4/3012:00 pm
BCN
- DSM
2 stops18h 49m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$829
Best flights from Des Moines to BarcelonaDiscover carefully curated flight deals from Des Moines to Barcelona that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 27, 2026.
Discover carefully curated flight deals from Des Moines to Barcelona that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 27, 2026.
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/25:25 pm
DSM
- BCN
2 stops14h 25m
Delta
Tue 9/1511:00 am
BCN
- DSM
1 stop30h 14m
Delta
Deal found 3/22![Delta logo]()
$795
This KLM deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/64:23 pm
DSM
- BCN
2 stops16h 12m
Multiple Airlines
Wed 5/1311:00 am
BCN
- DSM
1 stop13h 53m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$816
This British Airways deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:01 pm
DSM
- BCN
2 stops15h 54m
British Airways
Wed 5/1310:30 am
BCN
- DSM
1 stop16h 03m
British Airways
Deal found 3/25![British Airways logo]()
$831
This United Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/211:23 am
DSM
- BCN
2 stops20h 02m
United Airlines
Tue 9/153:15 pm
BCN
- DSM
1 stop16h 19m
United Airlines
Deal found 3/26![United Airlines logo]()
$844
This KLM deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/75:28 pm
DSM
- BCN
2 stops15h 07m
Multiple Airlines
Thu 5/1411:00 am
BCN
- DSM
1 stop18h 32m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$875
Last-minute flights from Des Moines to BarcelonaDiscover last-minute flight deals from Des Moines to Barcelona. Data last updated March 27, 2026 and is based on user searches.
Discover last-minute flight deals from Des Moines to Barcelona. Data last updated March 27, 2026 and is based on user searches.
This Justfly.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:00 am
DSM
- BCN
2 stops21h 20m
Aer Lingus
Fri 4/1711:00 am
BCN
- DSM
2 stops19h 49m
Aer Lingus
Deal found 3/25![Aer Lingus logo]()
$869
This British Airways deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:00 pm
DSM
- BCN
2 stops16h 45m
Multiple Airlines
Thu 4/3012:00 pm
BCN
- DSM
2 stops18h 49m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$829
This Priceline deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:03 pm
DSM
- BCN
1 stop31h 32m
British Airways
Thu 4/3012:00 pm
BCN
- DSM
2 stops18h 49m
British Airways
Deal found 3/24![British Airways logo]()
$853
This Ovago deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2311:51 am
DSM
- BCN
1 stop17h 59m
Scandinavian Airlines
Thu 4/3011:00 am
BCN
- DSM
1 stop31h 05m
Scandinavian Airlines
Deal found 3/24![Scandinavian Airlines logo]()
$859
This Cheapflightsfares deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:16 pm
DSM
- BCN
2 stops20h 09m
Lufthansa
Sat 5/21:50 pm
BCN
- DSM
2 stops16h 34m
Lufthansa
Deal found 3/26![Lufthansa logo]()
$860
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/272:44 pm
DSM
- BCN
1 stop15h 06m
Delta
Wed 5/2711:00 am
BCN
- DSM
1 stop18h 32m
Delta
Deal found 3/22![Delta logo]()
$831
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/272:44 pm
DSM
- BCN
1 stop15h 06m
Delta
Thu 5/2810:55 am
BCN
- DSM
2 stops18h 37m
Delta
Deal found 3/22![Delta logo]()
$836
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:45 pm
DSM
- BCN
2 stops14h 50m
Delta
Thu 5/2811:00 am
BCN
- DSM
1 stop18h 32m
Delta
Deal found 3/22![Delta logo]()
$835
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:45 pm
DSM
- BCN
2 stops16h 25m
Delta
Wed 5/276:20 am
BCN
- DSM
2 stops17h 46m
Delta
Deal found 3/22![Delta logo]()
$840
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2910:56 am
DSM
- BCN
2 stops16h 19m
Delta
Tue 5/269:20 am
BCN
- DSM
2 stops18h 16m
Delta
Deal found 3/22![Delta logo]()
$844
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3012:00 pm
DSM
- BCN
1 stop15h 35m
American Airlines
Tue 5/2612:20 pm
BCN
- DSM
1 stop17h 48m
American Airlines
Deal found 3/22![American Airlines logo]()
$881
This Delta deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/3010:56 am
DSM
- BCN
2 stops16h 19m
Delta
Wed 5/2711:00 am
BCN
- DSM
1 stop13h 53m
Delta
Deal found 3/22![Delta logo]()
$890
One-way flights from Des Moines to BarcelonaSearch for one-way flight options from Des Moines to Barcelona. Find affordable one-way fares based on user searches. Data last updated March 27, 2026.
Search for one-way flight options from Des Moines to Barcelona. Find affordable one-way fares based on user searches. Data last updated March 27, 2026.
This Trip.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1512:00 pm
DSM
- BCN
2 stops27h 30m
Aer Lingus
Deal found 3/26![Aer Lingus logo]()
$426
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/177:35 am
DSM
- BCN
2 stops22h 45m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$428
This Justfly.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:01 pm
DSM
- BCN
2 stops22h 29m
Aer Lingus
Deal found 3/23![Aer Lingus logo]()
$432
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:05 pm
DSM
- BCN
3 stops23h 30m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$436
This oojo deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:30 pm
DSM
- BCN
2 stops14h 30m
British Airways
Deal found 3/24![British Airways logo]()
$451
This Justfly.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/85:01 pm
DSM
- BCN
2 stops22h 29m
Aer Lingus
Deal found 3/22![Aer Lingus logo]()
$457
This Justfly.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1611:09 am
DSM
- BCN
2 stops28h 21m
Aer Lingus
Deal found 3/23![Aer Lingus logo]()
$459
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:14 pm
DSM
- BCN
3 stops41h 56m
Multiple Airlines
Deal found 3/23![Multiple Airlines logo]()
$465
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/167:30 am
DSM
- BCN
1 stop21h 40m
Multiple Airlines
Deal found 3/24![Multiple Airlines logo]()
$475
This Kiwi.com deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/810:01 pm
DSM
- BCN
3 stops57h 44m
Multiple Airlines
Deal found 3/22![Multiple Airlines logo]()
$480
This KAYAK deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1712:00 pm
DSM
- BCN
2 stops15h 20m
Aer Lingus
Deal found 3/23![Aer Lingus logo]()
$481
Find flight deals from Des Moines to Barcelona
Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Barcelona (S37). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 27, 2026.
Round-trip from | $795 (Delta) |
|---|---|
One-way from | $426 (Trip.com) |
Popular in | June |
Cheapest in | November |
Average price | $711 |
Cheapflights Fare Finder
Customize your flight search to find flights from Des Moines to Barcelona that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 27, 2026.
Use the filters below to find and compare flights from Des Moines to Barcelona that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesBarcelona
DSM - BCN
DSMBCN
Des Moines
Wed 9/2
5:25 pm-2:50 pm
2 stops14h 25m
Barcelona-El Prat
Tue 9/15
11:00 am-10:14 am
1 stop30h 14m
$795
Quickest round-trip
Des MoinesBarcelona
DSM - BCN
DSMBCN
Des Moines
Wed 5/6
4:23 pm-3:35 pm
2 stops16h 12m
Barcelona-El Prat
Wed 5/13
11:00 am-5:53 pm
1 stop13h 53m
$816
Des MoinesBarcelona
DSM - BCN
DSMBCN
Des Moines
Wed 5/6
5:01 pm-3:55 pm
2 stops15h 54m
Barcelona-El Prat
Wed 5/13
10:30 am-7:33 pm
1 stop16h 03m
$831
Des MoinesBarcelona
DSM - BCN
DSMBCN
Des Moines
Wed 9/2
11:23 am-2:25 pm
2 stops20h 02m
Barcelona-El Prat
Tue 9/15
3:15 pm-12:34 am
1 stop16h 19m
$844
Des MoinesBarcelona
DSM - BCN
DSMBCN
Des Moines
Thu 5/7
5:28 pm-3:35 pm
2 stops15h 07m
Barcelona-El Prat
Thu 5/14
11:00 am-10:32 pm
1 stop18h 32m
$875
Cheapest one-way
Des MoinesBarcelona
DSM - BCN
DSMBCN
Des Moines
Wed 4/15
12:00 pm-10:30 pm
2 stops27h 30m
$426
Des MoinesBarcelona
DSM - BCN
DSMBCN
Des Moines
Fri 7/17
7:35 am-1:20 pm
2 stops22h 45m
$428
Des MoinesBarcelona
DSM - BCN
DSMBCN
Des Moines
Thu 5/7
7:05 pm-1:35 am
3 stops23h 30m
$436
Quickest one-way
Des MoinesBarcelona
DSM - BCN
DSMBCN
Des Moines
Thu 7/16
6:30 pm-4:00 pm
2 stops14h 30m
$451
Des MoinesBarcelona
DSM - BCN
DSMBCN
Des Moines
Fri 5/8
5:01 pm-10:30 pm
2 stops22h 29m
$457
Showing 1-10 of 15 resultsSorted by cheapest first
Best time to book a flight from Des Moines to Barcelona
Have a flexible travel schedule? Discover the best time to fly to Barcelona from Des Moines with our price prediction graph.
DSM-S37
DSM-BCN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Des Moines to Barcelona
DSM-S37
DSM-BCN
What is the cheapest month to book a flight from Des Moines to Barcelona?
Currently, April is the cheapest month in which you can book a flight from Des Moines to Barcelona (average of $484). Flying from Des Moines to Barcelona in June is currently the most expensive (average of $1,242). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Des Moines to Barcelona?
Reviews of airlines servicing Barcelona
Get insights into the airlines that provide service to Barcelona. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Barcelona. Reviews last updated March 27, 2026.
Get a feel of what it's like to fly with United Airlines and American Airlines from Des Moines to Barcelona by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.1
Boarding
7.7
Comfort
7.3
Food
6.6
Crew
8.1
Overall
7.4
Reviews
1 / 20
10.0
ExcellentDane,Jan 2026
TYS - IAD
Entertainment
7.1
Boarding
7.7
Comfort
7.3
Food
6.6
Crew
8.1
Overall
7.4
Reviews
1 / 20
10.0
ExcellentDane,Jan 2026
TYS - IAD
Entertainment
7.1
Boarding
7.7
Comfort
7.3
Food
6.6
Crew
8.1
Overall
7.4
Reviews
1 / 20
10.0
ExcellentDane,Jan 2026
TYS - IAD
Related info for your journey
Find useful and relevant information for your journey from Des Moines to Barcelona. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Des Moines to Barcelona
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Complete your trip
Complete your trip to Barcelona by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Des Moines to Barcelona, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Des Moines and Barcelona flights
Browse other Des Moines and Barcelona flight options. Last updated on March 27, 2026.
Other flights from Des Moines
Browse through other flights departing from Des Moines. Flights are based on user searches made on Cheapflights and were last updated on March 27, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from Des Moines to Barcelona
Discover the top 2 airlines that operate flights from Des Moines to Barcelona. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$484 | Average$815 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$486 | Average$759 | FlexibilityNo cancel fee | On-time71% |