$249+ Cheap flights from St. Louis (STL) to Biloxi, MS
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/20. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MSY
Aug 14 — Aug 211
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from St. Louis to Biloxi with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from St. Louis to Biloxi
Cheapest
Best
Last-minute
One-way
Cheapest flights from St. Louis to BiloxiExplore the most affordable flight options available from St. Louis to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 15, 2026.
Explore the most affordable flight options available from St. Louis to Biloxi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 15, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:17 pm
STL
- GPT
2 stops13h 24m
Multiple Airlines
Sun 8/237:25 pm
GPT
- STL
1 stop20h 03m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/124:57 pm
STL
- GPT
2 stops25h 48m
Multiple Airlines
Sun 8/167:25 pm
GPT
- STL
1 stop28h 34m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$260
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1212:52 pm
STL
- GPT
1 stop4h 23m
Delta
Wed 8/196:00 pm
GPT
- STL
1 stop5h 21m
Delta
Deal found 7/10![Delta logo]()
$261
This Delta deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/185:23 pm
STL
- GPT
1 stop4h 58m
Delta
Mon 8/246:00 pm
GPT
- STL
1 stop5h 58m
Delta
Deal found 7/14![Delta logo]()
$286
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:12 pm
STL
- GPT
1 stop5h 44m
American Airlines
Tue 8/117:40 am
GPT
- STL
1 stop5h 22m
American Airlines
Deal found 7/9![American Airlines logo]()
$298
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:28 pm
STL
- GPT
1 stop4h 45m
Delta
Wed 11/46:05 pm
GPT
- STL
1 stop5h 43m
Delta
Deal found 7/10![Delta logo]()
$300
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/203:25 pm
STL
- GPT
1 stop7h 05m
American Airlines
Sun 8/235:50 pm
GPT
- STL
1 stop6h 04m
American Airlines
Deal found 7/10![American Airlines logo]()
$311
This American Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/75:42 am
STL
- GPT
1 stop4h 59m
American Airlines
Mon 8/105:45 pm
GPT
- STL
1 stop4h 55m
American Airlines
Deal found 7/11![American Airlines logo]()
$323
Best flights from St. Louis to BiloxiDiscover carefully curated flight deals from St. Louis to Biloxi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 15, 2026.
Discover carefully curated flight deals from St. Louis to Biloxi that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 15, 2026.
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1212:52 pm
STL
- GPT
1 stop4h 23m
Delta
Wed 8/196:00 pm
GPT
- STL
1 stop5h 21m
Delta
Deal found 7/10![Delta logo]()
$261
This American Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:00 am
STL
- GPT
2 stops8h 17m
American Airlines
Sat 8/155:45 pm
GPT
- STL
1 stop4h 55m
American Airlines
Deal found 7/11![American Airlines logo]()
$351
This United Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:00 am
STL
- GPT
2 stops10h 12m
United Airlines
Wed 8/192:00 pm
GPT
- STL
2 stops8h 59m
United Airlines
Deal found 7/12![United Airlines logo]()
$376
This Delta deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/185:23 pm
STL
- GPT
1 stop4h 58m
Delta
Mon 8/246:00 pm
GPT
- STL
1 stop5h 58m
Delta
Deal found 7/14![Delta logo]()
$286
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1212:52 pm
STL
- GPT
1 stop4h 23m
Delta
Mon 8/176:00 pm
GPT
- STL
1 stop5h 58m
Delta
Deal found 7/10![Delta logo]()
$286
This United Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/129:30 am
STL
- GPT
2 stops10h 08m
United Airlines
Wed 8/192:00 pm
GPT
- STL
2 stops8h 59m
United Airlines
Deal found 7/10![United Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/129:15 am
STL
- GPT
1 stop3h 48m
Delta
Fri 8/146:00 pm
GPT
- STL
1 stop17h 56m
Delta
Deal found 7/10![Delta logo]()
$366
This American Airlines deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1412:45 pm
STL
- GPT
2 stops9h 45m
American Airlines
Sun 8/165:50 pm
GPT
- STL
1 stop6h 04m
American Airlines
Deal found 7/12![American Airlines logo]()
$472
This Delta deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/183:39 pm
STL
- GPT
1 stop5h 00m
Delta
Mon 7/205:57 pm
GPT
- STL
1 stop4h 18m
Delta
Deal found 7/14![Delta logo]()
$393
This United Airlines deal was found by Cheapflights users on 7/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/286:14 am
STL
- GPT
1 stop7h 11m
United Airlines
Sat 8/12:00 pm
GPT
- STL
1 stop6h 40m
United Airlines
Deal found 7/13![United Airlines logo]()
$493
Last-minute flights from St. Louis to BiloxiDiscover last-minute flight deals from St. Louis to Biloxi. Data last updated July 15, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Biloxi. Data last updated July 15, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:12 pm
STL
- GPT
1 stop5h 44m
American Airlines
Tue 8/117:40 am
GPT
- STL
1 stop5h 22m
American Airlines
Deal found 7/9![American Airlines logo]()
$298
This American Airlines deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/75:42 am
STL
- GPT
1 stop4h 59m
American Airlines
Mon 8/105:45 pm
GPT
- STL
1 stop4h 55m
American Airlines
Deal found 7/11![American Airlines logo]()
$323
This American Airlines deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:00 am
STL
- GPT
2 stops11h 15m
American Airlines
Tue 8/1811:12 am
GPT
- STL
1 stop6h 53m
American Airlines
Deal found 7/14![American Airlines logo]()
$333
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/124:57 pm
STL
- GPT
2 stops25h 48m
Multiple Airlines
Sun 8/167:25 pm
GPT
- STL
1 stop28h 34m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$260
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1212:52 pm
STL
- GPT
1 stop4h 23m
Delta
Wed 8/196:00 pm
GPT
- STL
1 stop5h 21m
Delta
Deal found 7/10![Delta logo]()
$261
This Delta deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/185:23 pm
STL
- GPT
1 stop4h 58m
Delta
Mon 8/246:00 pm
GPT
- STL
1 stop5h 58m
Delta
Deal found 7/14![Delta logo]()
$286
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:17 pm
STL
- GPT
2 stops13h 24m
Multiple Airlines
Sun 8/237:25 pm
GPT
- STL
1 stop20h 03m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$249
This American Airlines deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/203:25 pm
STL
- GPT
1 stop7h 05m
American Airlines
Sun 8/235:50 pm
GPT
- STL
1 stop6h 04m
American Airlines
Deal found 7/10![American Airlines logo]()
$311
One-way flights from St. Louis to BiloxiSearch for one-way flight options from St. Louis to Biloxi. Find affordable one-way fares based on user searches. Data last updated July 15, 2026.
Search for one-way flight options from St. Louis to Biloxi. Find affordable one-way fares based on user searches. Data last updated July 15, 2026.
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/811:15 am
STL
- GPT
1 stop4h 57m
United Airlines
Deal found 7/9![United Airlines logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:08 pm
STL
- GPT
3 stops39h 13m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$618
Find flight deals from St. Louis to Biloxi
Keep the following information in mind while searching for St. Louis to Biloxi flight deals. Data was last updated July 15, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $249 (Kiwi.com) |
Popular in | August |
Cheapest in | January |
Average price | $502 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Biloxi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 15, 2026.
Use the filters below to find and compare flights from St. Louis to Biloxi that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisGulfport
STL - GPT
STLGPT
Lambert-St Louis
Wed 8/12
12:52 pm-5:15 pm
1 stop4h 23m
Gulfport Biloxi Regional
Wed 8/19
6:00 pm-11:21 pm
1 stop5h 21m
$261
St. LouisGulfport
STL - GPT
STLGPT
Lambert-St Louis
Tue 8/18
5:23 pm-10:21 pm
1 stop4h 58m
Gulfport Biloxi Regional
Mon 8/24
6:00 pm-11:58 pm
1 stop5h 58m
$286
St. LouisGulfport
STL - GPT
STLGPT
Lambert-St Louis
Wed 8/12
12:52 pm-5:15 pm
1 stop4h 23m
Gulfport Biloxi Regional
Mon 8/17
6:00 pm-11:58 pm
1 stop5h 58m
$286
St. LouisGulfport
STL - GPT
STLGPT
Lambert-St Louis
Sat 8/8
5:00 am-1:17 pm
2 stops8h 17m
Gulfport Biloxi Regional
Sat 8/15
5:45 pm-10:40 pm
1 stop4h 55m
$351
St. LouisGulfport
STL - GPT
STLGPT
Lambert-St Louis
Wed 8/12
9:15 am-1:03 pm
1 stop3h 48m
Gulfport Biloxi Regional
Fri 8/14
6:00 pm-11:56 am
1 stop17h 56m
$366
St. LouisGulfport
STL - GPT
STLGPT
Lambert-St Louis
Sat 8/15
6:00 am-4:12 pm
2 stops10h 12m
Gulfport Biloxi Regional
Wed 8/19
2:00 pm-10:59 pm
2 stops8h 59m
$376
Quickest round-trip
St. LouisGulfport
STL - GPT
STLGPT
Lambert-St Louis
Sat 7/18
3:39 pm-8:39 pm
1 stop5h 00m
Gulfport Biloxi Regional
Mon 7/20
5:57 pm-10:15 pm
1 stop4h 18m
$393
St. LouisGulfport
STL - GPT
STLGPT
Lambert-St Louis
Wed 8/12
9:30 am-7:38 pm
2 stops10h 08m
Gulfport Biloxi Regional
Wed 8/19
2:00 pm-10:59 pm
2 stops8h 59m
$399
St. LouisGulfport
STL - GPT
STLGPT
Lambert-St Louis
Fri 8/14
12:45 pm-10:30 pm
2 stops9h 45m
Gulfport Biloxi Regional
Sun 8/16
5:50 pm-11:54 pm
1 stop6h 04m
$472
St. LouisGulfport
STL - GPT
STLGPT
Lambert-St Louis
Tue 7/28
6:14 am-1:25 pm
1 stop7h 11m
Gulfport Biloxi Regional
Sat 8/1
2:00 pm-8:40 pm
1 stop6h 40m
$493
Showing 1-10 of 12 resultsSorted by cheapest first
Best time to book a flight from St. Louis to Biloxi
Have a flexible travel schedule? Discover the best time to fly to Biloxi from St. Louis with our price prediction graph.
STL-GPT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Biloxi
STL-B1L
STL-GPT
What is the cheapest time of day to fly from STL to B1L?
Find hourly flight availability from St. Louis to Biloxi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 15, 2026.
When flying from St. Louis to Biloxi, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 17% versus a flight in the afternoon.
Reviews of airlines servicing Biloxi
Get insights into the airlines that provide service to Biloxi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Biloxi. Reviews last updated July 15, 2026.
Peruse reviews from past customers who have flown with Delta and American Airlines from St. Louis to Biloxi to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Overall
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Overall
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Boarding
8.1
Crew
8.5
Comfort
7.8
Entertainment
7.8
Overall
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Biloxi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from St. Louis
Popular flights
Top destinations
Alternative routes for St. Louis to Biloxi
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Biloxi by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from St. Louis to Biloxi by cabin class
Find flights from St. Louis to Biloxi, based on your preferred cabin class, be it economy, premium economy, business, or first class.
St. Louis and Biloxi flights
Browse other St. Louis and Biloxi flight options. Last updated on July 15, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on July 15, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
St. Louis to Biloxi flights
Consider these flights traveling from St. Louis to Biloxi.
Top 6 airlines flying from St. Louis to Biloxi
Discover the top 6 airlines that operate flights from St. Louis to Biloxi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 15, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$82 | Average$227 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$93 | Average$365 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$118 | Average$206 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$196 | Average$392 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$236 | Average$367 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$247 | Average$433 | FlexibilityNo cancel fee | On-time63% |