$65+ Cheap flights from Buffalo to St. Louis (BUF - STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/16. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — STL
May 17 — May 241
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Buffalo to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Buffalo to St. Louis
Cheapest
Best
Last-minute
One-way
Cheapest flights from Buffalo to St. LouisExplore the most affordable flight options available from Buffalo to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2026.
Explore the most affordable flight options available from Buffalo to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1911:36 am
BUF
- STL
1 stop6h 57m
Frontier
Tue 5/266:33 pm
STL
- BUF
1 stop18h 21m
Frontier
Deal found 4/14![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/62:49 pm
BUF
- STL
1 stop27h 05m
Frontier
Tue 5/126:33 pm
STL
- BUF
1 stop18h 21m
Frontier
Deal found 4/15![Frontier logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/182:49 pm
BUF
- STL
1 stop27h 44m
Frontier
Wed 5/275:27 pm
STL
- BUF
1 stop16h 14m
Frontier
Deal found 4/14![Frontier logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1411:36 am
BUF
- STL
1 stop6h 18m
Frontier
Wed 5/205:27 pm
STL
- BUF
1 stop16h 14m
Frontier
Deal found 4/14![Frontier logo]()
$166
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/202:49 pm
BUF
- STL
1 stop26h 26m
Frontier
Tue 5/266:33 pm
STL
- BUF
1 stop18h 21m
Frontier
Deal found 4/14![Frontier logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/711:36 am
BUF
- STL
1 stop6h 18m
Frontier
Mon 5/115:27 pm
STL
- BUF
1 stop16h 14m
Frontier
Deal found 4/13![Frontier logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1411:36 am
BUF
- STL
1 stop6h 18m
Frontier
Mon 5/185:27 pm
STL
- BUF
1 stop16h 14m
Frontier
Deal found 4/13![Frontier logo]()
$172
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/292:49 pm
BUF
- STL
1 stop19h 06m
Frontier
Sun 5/314:19 pm
STL
- BUF
1 stop25h 40m
Frontier
Deal found 4/13![Frontier logo]()
$175
This Frontier deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:36 am
BUF
- STL
1 stop6h 57m
Frontier
Mon 6/111:24 am
STL
- BUF
1 stop6h 35m
Frontier
Deal found 4/13![Frontier logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/152:49 pm
BUF
- STL
1 stop19h 06m
Frontier
Tue 5/196:33 pm
STL
- BUF
1 stop18h 21m
Frontier
Deal found 4/13![Frontier logo]()
$193
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1911:36 am
BUF
- STL
1 stop6h 57m
Frontier
Wed 5/275:27 pm
STL
- BUF
2 stops25h 37m
Frontier
Deal found 4/14![Frontier logo]()
$197
Best flights from Buffalo to St. LouisDiscover carefully curated flight deals from Buffalo to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 17, 2026.
Discover carefully curated flight deals from Buffalo to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/52:49 pm
BUF
- STL
1 stop19h 06m
Frontier
Sun 6/78:08 pm
STL
- BUF
2 stops16h 46m
Frontier
Deal found 4/12![Frontier logo]()
$221
This Southwest deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/158:00 pm
BUF
- STL
1 stop3h 45m
Southwest
Tue 5/1910:25 am
STL
- BUF
1 stop3h 55m
Southwest
Deal found 4/13![Southwest logo]()
$332
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/187:39 pm
BUF
- STL
1 stop5h 20m
Delta
Thu 5/286:04 pm
STL
- BUF
1 stop4h 55m
Delta
Deal found 4/14![Delta logo]()
$354
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:10 am
BUF
- STL
2 stops9h 22m
United Airlines
Tue 5/129:21 am
STL
- BUF
1 stop6h 33m
United Airlines
Deal found 4/16![United Airlines logo]()
$372
This CheapOair deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/157:57 pm
BUF
- STL
1 stop29h 12m
Frontier
Wed 6/174:17 pm
STL
- BUF
1 stop25h 55m
Frontier
Deal found 4/15![Frontier logo]()
$261
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/157:55 pm
BUF
- STL
1 stop3h 55m
Southwest
Wed 6/173:15 pm
STL
- BUF
2 stops6h 25m
Southwest
Deal found 4/15![Southwest logo]()
$377
This United Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:00 am
BUF
- STL
2 stops7h 11m
United Airlines
Mon 6/19:23 am
STL
- BUF
1 stop6h 23m
United Airlines
Deal found 4/14![United Airlines logo]()
$406
This Kiwi.com deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/34:07 pm
BUF
- STL
2 stops15h 43m
Frontier
Thu 5/76:55 pm
STL
- BUF
1 stop17h 59m
Frontier
Deal found 4/17![Frontier logo]()
$370
This Southwest deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/139:40 am
BUF
- STL
2 stops6h 40m
Southwest
Sun 8/166:00 am
STL
- BUF
1 stop3h 50m
Southwest
Deal found 4/12![Southwest logo]()
$412
This Southwest deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/187:35 am
BUF
- STL
2 stops7h 15m
Southwest
Mon 6/224:35 pm
STL
- BUF
2 stops6h 35m
Southwest
Deal found 4/13![Southwest logo]()
$417
This Southwest deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/84:00 pm
BUF
- STL
2 stops8h 15m
Southwest
Sun 5/105:05 am
STL
- BUF
1 stop5h 50m
Southwest
Deal found 4/12![Southwest logo]()
$422
Last-minute flights from Buffalo to St. LouisDiscover last-minute flight deals from Buffalo to St. Louis. Data last updated April 17, 2026 and is based on user searches.
Discover last-minute flight deals from Buffalo to St. Louis. Data last updated April 17, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/62:49 pm
BUF
- STL
1 stop27h 05m
Frontier
Tue 5/126:33 pm
STL
- BUF
1 stop18h 21m
Frontier
Deal found 4/15![Frontier logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/711:36 am
BUF
- STL
1 stop6h 18m
Frontier
Mon 5/115:27 pm
STL
- BUF
1 stop16h 14m
Frontier
Deal found 4/13![Frontier logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1411:36 am
BUF
- STL
1 stop6h 18m
Frontier
Wed 5/205:27 pm
STL
- BUF
1 stop16h 14m
Frontier
Deal found 4/14![Frontier logo]()
$166
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1411:36 am
BUF
- STL
1 stop6h 18m
Frontier
Mon 5/185:27 pm
STL
- BUF
1 stop16h 14m
Frontier
Deal found 4/13![Frontier logo]()
$172
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/152:49 pm
BUF
- STL
1 stop19h 06m
Frontier
Tue 5/196:33 pm
STL
- BUF
1 stop18h 21m
Frontier
Deal found 4/13![Frontier logo]()
$193
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/182:49 pm
BUF
- STL
1 stop27h 44m
Frontier
Wed 5/275:27 pm
STL
- BUF
1 stop16h 14m
Frontier
Deal found 4/14![Frontier logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1911:36 am
BUF
- STL
1 stop6h 57m
Frontier
Wed 5/275:27 pm
STL
- BUF
1 stop16h 14m
Frontier
Deal found 4/14![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/202:49 pm
BUF
- STL
1 stop26h 26m
Frontier
Wed 5/275:27 pm
STL
- BUF
1 stop16h 14m
Frontier
Deal found 4/14![Frontier logo]()
$169
This Frontier deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:36 am
BUF
- STL
1 stop6h 57m
Frontier
Mon 6/111:24 am
STL
- BUF
1 stop6h 35m
Frontier
Deal found 4/13![Frontier logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/292:49 pm
BUF
- STL
1 stop19h 06m
Frontier
Sun 5/314:19 pm
STL
- BUF
1 stop25h 40m
Frontier
Deal found 4/13![Frontier logo]()
$175
One-way flights from Buffalo to St. LouisSearch for one-way flight options from Buffalo to St. Louis. Find affordable one-way fares based on user searches. Data last updated April 17, 2026.
Search for one-way flight options from Buffalo to St. Louis. Find affordable one-way fares based on user searches. Data last updated April 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1611:50 am
BUF
- STL
1 stop22h 02m
Frontier
Deal found 4/13![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/152:49 pm
BUF
- STL
1 stop19h 06m
Frontier
Deal found 4/15![Frontier logo]()
$70
This Priceline deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1411:36 am
BUF
- STL
1 stop6h 18m
Frontier
Deal found 4/15![Frontier logo]()
$90
This Priceline deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/2311:50 am
BUF
- STL
1 stop6h 40m
Frontier
Deal found 4/13![Frontier logo]()
$95
This Expedia deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2711:19 am
BUF
- STL
1 stop13h 00m
Frontier
Deal found 4/13![Frontier logo]()
$96
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/82:49 pm
BUF
- STL
1 stop27h 41m
Frontier
Deal found 4/15![Frontier logo]()
$104
This Priceline deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/711:36 am
BUF
- STL
1 stop6h 57m
Frontier
Deal found 4/15![Frontier logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/227:57 pm
BUF
- STL
2 stops22h 33m
Frontier
Deal found 4/13![Frontier logo]()
$113
This Frontier deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1811:35 am
BUF
- STL
1 stop6h 55m
Frontier
Deal found 4/13![Frontier logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/87:52 pm
BUF
- STL
2 stops37h 55m
Multiple Airlines
Deal found 4/15![Multiple Airlines logo]()
$116
This Trip.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/211:44 am
BUF
- STL
1 stop12h 35m
Frontier
Deal found 4/14![Frontier logo]()
$121
Find flight deals from Buffalo to St. Louis
Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $126 (Kiwi.com) |
One-way from | $65 (Kiwi.com) |
Popular in | March |
Cheapest in | December |
Average price | $393 |
Cheapflights Fare Finder
Customize your flight search to find flights from Buffalo to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2026.
Use the filters below to find and compare flights from Buffalo to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
BuffaloSt. Louis
BUF - STL
BUFSTL
Buffalo
Fri 6/5
2:49 pm-8:55 am
1 stop19h 06m
Lambert-St Louis
Sun 6/7
8:08 pm-1:54 pm
2 stops16h 46m
$221
BuffaloSt. Louis
BUF - STL
BUFSTL
Buffalo
Mon 6/15
7:57 pm-12:09 am
1 stop29h 12m
Lambert-St Louis
Wed 6/17
4:17 pm-7:12 pm
1 stop25h 55m
$261
Quickest round-trip
BuffaloSt. Louis
BUF - STL
BUFSTL
Buffalo
Fri 5/15
8:00 pm-10:45 pm
1 stop3h 45m
Lambert-St Louis
Tue 5/19
10:25 am-3:20 pm
1 stop3h 55m
$332
BuffaloSt. Louis
BUF - STL
BUFSTL
Buffalo
Mon 5/18
7:39 pm-11:59 pm
1 stop5h 20m
Lambert-St Louis
Thu 5/28
6:04 pm-11:59 pm
1 stop4h 55m
$354
BuffaloSt. Louis
BUF - STL
BUFSTL
Buffalo
Sun 5/3
4:07 pm-6:50 am
2 stops15h 43m
Lambert-St Louis
Thu 5/7
6:55 pm-1:54 pm
1 stop17h 59m
$370
BuffaloSt. Louis
BUF - STL
BUFSTL
Buffalo
Sat 5/9
6:10 am-2:32 pm
2 stops9h 22m
Lambert-St Louis
Tue 5/12
9:21 am-4:54 pm
1 stop6h 33m
$372
BuffaloSt. Louis
BUF - STL
BUFSTL
Buffalo
Mon 6/15
7:55 pm-10:50 pm
1 stop3h 55m
Lambert-St Louis
Wed 6/17
3:15 pm-10:40 pm
2 stops6h 25m
$377
BuffaloSt. Louis
BUF - STL
BUFSTL
Buffalo
Thu 5/28
6:00 am-12:11 pm
2 stops7h 11m
Lambert-St Louis
Mon 6/1
9:23 am-4:46 pm
1 stop6h 23m
$406
BuffaloSt. Louis
BUF - STL
BUFSTL
Buffalo
Thu 8/13
9:40 am-3:20 pm
2 stops6h 40m
Lambert-St Louis
Sun 8/16
6:00 am-10:50 am
1 stop3h 50m
$412
BuffaloSt. Louis
BUF - STL
BUFSTL
Buffalo
Thu 6/18
7:35 am-1:50 pm
2 stops7h 15m
Lambert-St Louis
Mon 6/22
4:35 pm-12:10 am
2 stops6h 35m
$417
Showing 1-10 of 22 resultsSorted by cheapest first
Compare providers for flights from Buffalo to St. Louis
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to St. Louis in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Buffalo-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Buffalo-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Buffalo-St. Louis flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Buffalo-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Buffalo to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Buffalo with our price prediction graph.
BUF-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Buffalo to St. Louis
What is the cheapest month to book a flight from Buffalo to St. Louis?
Currently, December is the cheapest month in which you can book a flight from Buffalo to St. Louis (average of $319). Flying from Buffalo to St. Louis in March is currently the most expensive (average of $637). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Buffalo to St. Louis?
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated April 17, 2026.
Read through reviews of airlines operating flights from Buffalo to St. Louis, such as Southwest,Delta, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Food
7.0
Overall
8.0
Crew
8.6
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Overall
8.0
Crew
8.6
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Overall
8.0
Crew
8.6
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Food
7.0
Overall
8.0
Crew
8.6
Comfort
8.0
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Buffalo to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsEdwardsville
O'Fallon
Fenton
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Wentzville
Glencoe
Chesterfield
Alton
Farmington
Festus
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Buffalo
Popular flights
St. Louis flight routes
Alternative routes for Buffalo to St. Louis
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to St. Louis by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Buffalo to St. Louis by cabin class
Find flights from Buffalo to St. Louis, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Buffalo and St. Louis flights
Browse other Buffalo and St. Louis flight options. Last updated on April 17, 2026.
Other flights from Buffalo
Browse through other flights departing from Buffalo. Flights are based on user searches made on Cheapflights and were last updated on April 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to St. Louis
Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 17, 2026.
Top 3 airlines flying from Buffalo to St. Louis
Discover the top 3 airlines that operate flights from Buffalo to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$164 | Average$352 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$236 | Average$341 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$317 | Average$456 | FlexibilityNo cancel fee | On-time63% |