$125+ Cheap flights from Buffalo to San Diego (BUF - SAN)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/29. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — SAN
Jun 4 — Jun 111
Round-trip
1 adult, Economy
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Find cheap flights from Buffalo to San Diego with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Buffalo to San DiegoExplore the most affordable flight options available from Buffalo to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 5, 2026.
Explore the most affordable flight options available from Buffalo to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 5, 2026.
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/224:59 pm
BUF
- SAN
1 stop9h 04m
Delta
Tue 12/110:30 pm
SAN
- BUF
1 stop6h 59m
Delta
Deal found 4/30![Delta logo]()
$348
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/294:55 pm
BUF
- SAN
1 stop9h 32m
Delta
Tue 6/22:30 pm
SAN
- BUF
1 stop6h 29m
Delta
Deal found 5/3![Delta logo]()
$349
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/127:20 am
BUF
- SAN
2 stops9h 20m
Southwest
Sun 11/2210:40 pm
SAN
- BUF
1 stop8h 45m
Southwest
Deal found 5/1![Southwest logo]()
$354
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/31:10 pm
BUF
- SAN
1 stop8h 45m
Southwest
Mon 6/85:10 pm
SAN
- BUF
2 stops14h 15m
Southwest
Deal found 5/4![Southwest logo]()
$360
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/14:00 pm
BUF
- SAN
2 stops10h 05m
Southwest
Mon 6/85:10 pm
SAN
- BUF
2 stops14h 15m
Southwest
Deal found 5/4![Southwest logo]()
$365
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1211:34 am
BUF
- SAN
1 stop10h 19m
American Airlines
Sun 11/2210:41 pm
SAN
- BUF
1 stop9h 28m
American Airlines
Deal found 5/4![American Airlines logo]()
$369
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:40 pm
BUF
- SAN
1 stop9h 20m
Southwest
Tue 6/27:40 pm
SAN
- BUF
2 stops9h 10m
Southwest
Deal found 5/3![Southwest logo]()
$379
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/132:25 pm
BUF
- SAN
2 stops10h 30m
Southwest
Thu 10/298:15 pm
SAN
- BUF
2 stops8h 40m
Southwest
Deal found 5/4![Southwest logo]()
$380
This American Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2612:51 pm
BUF
- SAN
1 stop11h 02m
American Airlines
Thu 6/410:05 am
SAN
- BUF
1 stop8h 47m
American Airlines
Deal found 5/2![American Airlines logo]()
$381
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/246:00 am
BUF
- SAN
1 stop9h 23m
American Airlines
Tue 12/299:40 am
SAN
- BUF
1 stop9h 49m
American Airlines
Deal found 5/1![American Airlines logo]()
$385
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/224:57 pm
BUF
- SAN
1 stop7h 32m
American Airlines
Mon 5/2510:45 pm
SAN
- BUF
1 stop7h 46m
American Airlines
Deal found 4/30![American Airlines logo]()
$389
Best flights from Buffalo to San DiegoDiscover carefully curated flight deals from Buffalo to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 5, 2026.
Discover carefully curated flight deals from Buffalo to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 5, 2026.
This United Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/267:00 am
BUF
- SAN
1 stop7h 21m
United Airlines
Sat 5/3010:55 am
SAN
- BUF
1 stop9h 03m
United Airlines
Deal found 5/3![United Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/167:36 pm
BUF
- SAN
1 stop6h 54m
Delta
Mon 7/202:40 pm
SAN
- BUF
1 stop6h 18m
Delta
Deal found 5/1![Delta logo]()
$349
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/302:50 pm
BUF
- SAN
1 stop11h 30m
Southwest
Fri 8/710:40 pm
SAN
- BUF
1 stop8h 15m
Southwest
Deal found 5/1![Southwest logo]()
$354
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/316:50 am
BUF
- SAN
2 stops9h 20m
Southwest
Sun 9/610:40 pm
SAN
- BUF
1 stop9h 30m
Southwest
Deal found 5/3![Southwest logo]()
$354
This Delta deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:15 am
BUF
- SAN
1 stop8h 01m
Delta
Thu 6/410:53 am
SAN
- BUF
1 stop10h 06m
Delta
Deal found 5/2![Delta logo]()
$414
This United Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/196:04 pm
BUF
- SAN
1 stop7h 35m
United Airlines
Thu 6/2510:25 pm
SAN
- BUF
1 stop8h 35m
United Airlines
Deal found 5/2![United Airlines logo]()
$445
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/145:15 am
BUF
- SAN
1 stop7h 10m
Southwest
Fri 6/1910:40 pm
SAN
- BUF
1 stop8h 40m
Southwest
Deal found 5/4![Southwest logo]()
$412
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/84:40 pm
BUF
- SAN
2 stops9h 25m
Southwest
Wed 6/177:15 am
SAN
- BUF
2 stops11h 10m
Southwest
Deal found 5/4![Southwest logo]()
$415
This Southwest deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/97:10 pm
BUF
- SAN
1 stop7h 10m
Southwest
Fri 6/1211:55 am
SAN
- BUF
2 stops9h 15m
Southwest
Deal found 5/1![Southwest logo]()
$417
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/184:10 pm
BUF
- SAN
1 stop10h 15m
Southwest
Sun 6/2112:45 pm
SAN
- BUF
1 stop8h 25m
Southwest
Deal found 5/4![Southwest logo]()
$417
Last-minute flights from Buffalo to San DiegoDiscover last-minute flight deals from Buffalo to San Diego. Data last updated May 5, 2026 and is based on user searches.
Discover last-minute flight deals from Buffalo to San Diego. Data last updated May 5, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/224:57 pm
BUF
- SAN
1 stop7h 32m
American Airlines
Mon 5/2510:45 pm
SAN
- BUF
1 stop7h 46m
American Airlines
Deal found 4/30![American Airlines logo]()
$389
This American Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2612:51 pm
BUF
- SAN
1 stop11h 02m
American Airlines
Thu 6/410:05 am
SAN
- BUF
1 stop8h 47m
American Airlines
Deal found 5/2![American Airlines logo]()
$381
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/263:10 pm
BUF
- SAN
2 stops9h 20m
Southwest
Sat 5/309:40 pm
SAN
- BUF
1 stop7h 35m
Southwest
Deal found 5/4![Southwest logo]()
$409
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2812:40 pm
BUF
- SAN
1 stop9h 20m
Southwest
Tue 6/27:40 pm
SAN
- BUF
2 stops9h 10m
Southwest
Deal found 5/3![Southwest logo]()
$379
This Delta deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/294:55 pm
BUF
- SAN
1 stop9h 32m
Delta
Tue 6/22:30 pm
SAN
- BUF
1 stop6h 29m
Delta
Deal found 5/3![Delta logo]()
$349
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/14:00 pm
BUF
- SAN
2 stops10h 05m
Southwest
Mon 6/810:40 pm
SAN
- BUF
1 stop8h 45m
Southwest
Deal found 5/4![Southwest logo]()
$354
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/31:10 pm
BUF
- SAN
1 stop8h 45m
Southwest
Mon 6/85:10 pm
SAN
- BUF
2 stops14h 15m
Southwest
Deal found 5/4![Southwest logo]()
$360
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/84:40 pm
BUF
- SAN
1 stop9h 35m
Southwest
Wed 6/177:15 am
SAN
- BUF
2 stops11h 10m
Southwest
Deal found 5/4![Southwest logo]()
$410
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1112:47 pm
BUF
- SAN
1 stop8h 48m
American Airlines
Thu 6/1110:45 pm
SAN
- BUF
1 stop7h 44m
American Airlines
Deal found 5/4![American Airlines logo]()
$411
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/155:55 pm
BUF
- SAN
1 stop8h 25m
Southwest
Wed 6/2410:40 pm
SAN
- BUF
1 stop8h 45m
Southwest
Deal found 5/4![Southwest logo]()
$405
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1712:47 pm
BUF
- SAN
1 stop11h 06m
American Airlines
Sat 6/2010:59 am
SAN
- BUF
1 stop8h 36m
American Airlines
Deal found 5/5![American Airlines logo]()
$369
One-way flights from Buffalo to San DiegoSearch for one-way flight options from Buffalo to San Diego. Find affordable one-way fares based on user searches. Data last updated May 5, 2026.
Search for one-way flight options from Buffalo to San Diego. Find affordable one-way fares based on user searches. Data last updated May 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/292:50 pm
BUF
- SAN
2 stops20h 58m
Frontier
Deal found 5/4![Frontier logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/2311:50 am
BUF
- SAN
2 stops39h 03m
Frontier
Deal found 5/1![Frontier logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/2012:29 pm
BUF
- SAN
2 stops23h 19m
Frontier
Deal found 5/1![Frontier logo]()
$145
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3011:50 am
BUF
- SAN
2 stops24h 19m
Frontier
Deal found 5/4![Frontier logo]()
$149
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/292:50 pm
BUF
- SAN
2 stops21h 15m
Frontier
Deal found 5/3![Frontier logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1811:35 am
BUF
- SAN
2 stops39h 18m
Frontier
Deal found 5/3![Frontier logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/242:50 pm
BUF
- SAN
2 stops20h 58m
Frontier
Deal found 5/1![Frontier logo]()
$174
This Delta deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/134:30 pm
BUF
- SAN
1 stop9h 14m
Delta
Deal found 4/30![Delta logo]()
$175
This Southwest deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/184:10 pm
BUF
- SAN
1 stop10h 15m
Southwest
Deal found 5/3![Southwest logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/3012:41 pm
BUF
- SAN
2 stops47h 01m
Frontier
Deal found 4/30![Frontier logo]()
$192
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1911:36 am
BUF
- SAN
2 stops34h 03m
Frontier
Deal found 5/4![Frontier logo]()
$194
This Kiwi.com deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/262:50 pm
BUF
- SAN
2 stops36h 25m
Frontier
Deal found 5/1![Frontier logo]()
$201
Find flight deals from Buffalo to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $349 (Delta) |
One-way from | $133 (Kiwi.com) |
Popular in | December |
Cheapest in | October |
Average price | $392 |
Cheapflights Fare Finder
Customize your flight search to find flights from Buffalo to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 5, 2026.
Use the filters below to find and compare flights from Buffalo to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
BuffaloSan Diego
BUF - SAN
BUFSAN
Buffalo
Tue 5/26
7:00 am-11:21 am
1 stop7h 21m
San Diego
Sat 5/30
10:55 am-10:58 pm
1 stop9h 03m
$349
Quickest round-trip
BuffaloSan Diego
BUF - SAN
BUFSAN
Buffalo
Thu 7/16
7:36 pm-11:30 pm
1 stop6h 54m
San Diego
Mon 7/20
2:40 pm-11:58 pm
1 stop6h 18m
$349
BuffaloSan Diego
BUF - SAN
BUFSAN
Buffalo
Thu 7/30
2:50 pm-11:20 pm
1 stop11h 30m
San Diego
Fri 8/7
10:40 pm-9:55 am
1 stop8h 15m
$354
BuffaloSan Diego
BUF - SAN
BUFSAN
Buffalo
Mon 8/31
6:50 am-1:10 pm
2 stops9h 20m
San Diego
Sun 9/6
10:40 pm-11:10 am
1 stop9h 30m
$354
BuffaloSan Diego
BUF - SAN
BUFSAN
Buffalo
Sun 6/14
5:15 am-9:25 am
1 stop7h 10m
San Diego
Fri 6/19
10:40 pm-10:20 am
1 stop8h 40m
$412
BuffaloSan Diego
BUF - SAN
BUFSAN
Buffalo
Tue 5/26
6:15 am-11:16 am
1 stop8h 01m
San Diego
Thu 6/4
10:53 am-11:59 pm
1 stop10h 06m
$414
BuffaloSan Diego
BUF - SAN
BUFSAN
Buffalo
Mon 6/8
4:40 pm-11:05 pm
2 stops9h 25m
San Diego
Wed 6/17
7:15 am-9:25 pm
2 stops11h 10m
$415
BuffaloSan Diego
BUF - SAN
BUFSAN
Buffalo
Tue 6/9
7:10 pm-11:20 pm
1 stop7h 10m
San Diego
Fri 6/12
11:55 am-12:10 am
2 stops9h 15m
$417
BuffaloSan Diego
BUF - SAN
BUFSAN
Buffalo
Thu 6/18
4:10 pm-11:25 pm
1 stop10h 15m
San Diego
Sun 6/21
12:45 pm-12:10 am
1 stop8h 25m
$417
BuffaloSan Diego
BUF - SAN
BUFSAN
Buffalo
Fri 6/19
6:04 pm-10:39 pm
1 stop7h 35m
San Diego
Thu 6/25
10:25 pm-10:00 am
1 stop8h 35m
$445
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Buffalo to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to San Diego in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Buffalo-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Buffalo-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Buffalo-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Buffalo-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Buffalo to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Buffalo with our price prediction graph.
BUF-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Buffalo to San Diego
How far ahead should I book a flight from Buffalo to San Diego?
Booking 52 days in advance of your planned departure date is, on average, the best time to get cheap flights from Buffalo to San Diego. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Buffalo to San Diego?
Currently, October is the cheapest month in which you can book a flight from Buffalo to San Diego (average of $351). Flying from Buffalo to San Diego in December is currently the most expensive (average of $520). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Buffalo to San Diego?
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated May 5, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Buffalo to San Diego by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Comfort
8.0
Food
7.0
Crew
8.6
Entertainment
7.5
Overall
7.9
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Comfort
8.0
Food
7.0
Crew
8.6
Entertainment
7.5
Overall
7.9
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Comfort
8.0
Food
7.0
Crew
8.6
Entertainment
7.5
Overall
7.9
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Comfort
8.0
Food
7.0
Crew
8.6
Entertainment
7.5
Overall
7.9
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Comfort
8.0
Food
7.0
Crew
8.6
Entertainment
7.5
Overall
7.9
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Comfort
8.0
Food
7.0
Crew
8.6
Entertainment
7.5
Overall
7.9
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Buffalo to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
Chula Vista
National City
Coronado
La Mesa
Poway
Julian
Lemon Grove
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Buffalo and San Diego flights
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Top 5 airlines flying from Buffalo to San Diego
Discover the top 5 airlines that operate flights from Buffalo to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$172 | Average$328 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$222 | Average$365 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$245 | Average$351 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$267 | Average$405 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$296 | Average$432 | FlexibilityNo cancel fee | On-time69% |