Tuscany

$410+ Cheap flights from Knoxville (TYS) to Tuscany

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/15. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — FLR
Dec 14 — Dec 211
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Knoxville to Tuscany with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Knoxville to Tuscany

Cheapest flights from Knoxville to Tuscany
Explore the most affordable flight options available from Knoxville to Tuscany. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 14, 2025.

This KLM deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/102:37 pmTYS - FCO
1 stop11h 18mKLM
Wed 12/1710:05 amFCO - TYS
1 stop17h 54mKLM
Deal found 11/12$506
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/107:25 pmTYS - FCO
1 stop31h 05mUnited Airlines
Wed 12/179:45 amFCO - TYS
2 stops19h 59mUnited Airlines
Deal found 11/12$510
This United Airlines deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/52:30 pmTYS - FCO
1 stop12h 00mUnited Airlines
Fri 12/121:10 pmFCO - TYS
2 stops37h 54mUnited Airlines
Deal found 11/14$677
This Cheapflightsfares deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/47:25 pmTYS - FCO
2 stops21h 35mLufthansa
Mon 12/89:45 amFCO - TYS
2 stops15h 44mLufthansa
Deal found 11/13$690
This Delta deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/108:35 amTYS - FCO
2 stops16h 30mDelta
Wed 12/1712:40 pmFCO - TYS
1 stop15h 19mDelta
Deal found 11/13$699
This KLM deal was found by Cheapflights users on 11/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/511:26 amTYS - FCO
1 stop14h 29mKLM
Fri 12/1212:40 pmFCO - TYS
1 stop14h 50mKLM
Deal found 11/14$700
This American Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/44:31 pmTYS - FCO
2 stops16h 49mAmerican Airlines
Mon 12/811:00 amFCO - TYS
1 stop15h 48mAmerican Airlines
Deal found 11/13$702
This KLM deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/43:57 pmTYS - FCO
1 stop12h 33mKLM
Mon 12/810:05 amFCO - TYS
1 stop19h 23mKLM
Deal found 11/13$706
This Finnair deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:35 amTYS - FCO
1 stop19h 25mMultiple Airlines
Thu 1/87:00 pmFCO - TYS
2 stops33h 47mMultiple Airlines
Deal found 11/13$737

Cheap flight deals from Knoxville to Tuscany

Keep the following information in mind while searching for Knoxville to Tuscany flight deals. Data was last updated November 14, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$483
(United Airlines)

One-way from

$410
(Mytrip)

Popular in

March

Cheapest in

October

Average price

$1,074
Provider with most accurate pricing for Knoxville McGhee Tyson-Florence Peretola flight deals.
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Florence Peretola flights.
From Knoxville McGhee Tyson to Tuscany
One-way flight from Knoxville McGhee Tyson to Tuscany
Highest demand for flights based on searches. 13% potential increase in price ($190 potential increase over avg. RT price).
Cheapest flight prices on average. 3% potential price decrease ($47 potential savings vs. average RT price).
Average for round-trip flights in November 2025

Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Tuscany that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 14, 2025.
Use the filters below to find and compare flights from Knoxville to Tuscany that are best for you.

Fly from

Knoxville

Fly to

Tuscany

Route

Depart

Return

Price

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Wed 12/10

2:37 pm-7:55 am

1 stop11h 18m

Rome Fiumicino

Wed 12/17

10:05 am-9:59 pm

1 stop17h 54m

$506

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Wed 12/10

7:25 pm-8:30 am

1 stop31h 05m

Rome Fiumicino

Wed 12/17

9:45 am-11:44 pm

2 stops19h 59m

$510

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Wed 12/10

5:40 am-7:05 am

2 stops19h 25m

Rome Fiumicino

Wed 12/17

9:20 am-9:38 am

2 stops30h 18m

$510

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Fri 12/5

2:30 pm-8:30 am

1 stop12h 00m

Rome Fiumicino

Fri 12/12

1:10 pm-9:04 pm

2 stops37h 54m

$677

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Wed 3/11

2:30 pm-1:35 pm

2 stops18h 05m

Florence Peretola

Wed 3/18

6:30 am-8:54 pm

2 stops19h 24m

$691

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Wed 3/11

7:00 am-1:50 pm

3 stops25h 50m

Florence Peretola

Wed 3/18

6:30 am-8:54 pm

2 stops19h 24m

$698

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Wed 12/31

7:35 am-9:00 am

1 stop19h 25m

Rome Fiumicino

Thu 1/8

7:00 pm-10:47 pm

2 stops33h 47m

$737

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Mon 3/9

7:00 am-7:55 am

2 stops19h 55m

Rome Fiumicino

Sun 3/15

12:20 pm-10:48 am

2 stops27h 28m

$759

KnoxvilleRome

TYS - FCO

TYSFCO

Knoxville McGhee Tyson

Mon 1/5

9:50 am-11:00 pm

2 stops31h 10m

Rome Fiumicino

Mon 1/12

9:45 am-9:02 pm

2 stops17h 17m

$811

KnoxvilleFlorence

TYS - FLR

TYSFLR

Knoxville McGhee Tyson

Mon 1/26

5:15 pm-11:20 am

2 stops36h 05m

Florence Peretola

Sat 5/16

7:10 am-8:39 pm

2 stops19h 29m

$821

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/12

Showing 1-10 of 24 results
1
2
3

Best time to book a flight from Knoxville to Tuscany

Have a flexible travel schedule? Discover the best time to fly to Tuscany from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Tuscany

What is the cheapest time of day to fly from TYS to TO?

Find hourly flight availability from Knoxville to Tuscany. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 14, 2025.

One of the essential ways to save on airfare from Knoxville to Tuscany is to remain as flexible as possible. Flights that are in the evening tend to be the most expensive. A flight in the afternoon could potentially save you up to 16% on airfare.

Reviews of airlines servicing Tuscany

Get insights into the airlines that provide service to Tuscany. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Tuscany. Reviews last updated November 14, 2025.
Read reviews from past customers who have flown Delta, United Airlines, and Lufthansa from Knoxville to Tuscany. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Crew

8.5

Entertainment

7.9

Boarding

8.1

Overall

7.9

Comfort

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Crew

8.5

Entertainment

7.9

Boarding

8.1

Overall

7.9

Comfort

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Crew

8.5

Entertainment

7.9

Boarding

8.1

Overall

7.9

Comfort

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Crew

8.5

Entertainment

7.9

Boarding

8.1

Overall

7.9

Comfort

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Tuscany. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Knoxville to Tuscany?

    For a flight from Knoxville to Tuscany, you will be flying from McGhee Tyson. Knoxville McGhee Tyson (TYS) is just 11.3 mi from the center of the city.

  • How long is the flight from Knoxville to Tuscany?

    There are many flights that can get you from Knoxville to Tuscany in 11h 18m. Fly via KLM, United Airlines, or Delta to get the fastest option. The distance from Knoxville to Tuscany is about 4908 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Knoxville to Tuscany that include hotel bookings?

    Yes. In addition to deals on Knoxville to Tuscany flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Tuscany?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Tuscany.

  • Can I find deals for business class flights from Knoxville to Tuscany?

    Yes. Cheapflights offers flight deals from Knoxville to Tuscany by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 3 airlines flying from Knoxville to Tuscany

Discover the top 3 airlines that operate flights from Knoxville to Tuscany. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
LufthansaCheapest$649Average$1,106FlexibilityNo cancel feeOn-time76%
DeltaCheapest$832Average$1,279FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$894Average$1,147FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.