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$165+ Cheap flights from Roanoke to St. Louis (ROA - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/18. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — STL
Feb 26 — Mar 51
Thu 2/26
Thu 3/5
1 adult, Economy
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Cheap flight deals from Roanoke to St. Louis

Cheapest flights from Roanoke to St. Louis
Explore the most affordable flight options available from Roanoke to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/166:00 am
ROA
-
STL
1 stop6h 09m
Delta
Tue 3/315:21 pm
STL
-
ROA
1 stop5h 43m
Delta
Deal found 1/27$269
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/117:59 pm
ROA
-
STL
1 stop4h 38m
Delta
Mon 2/166:47 pm
STL
-
ROA
1 stop4h 19m
Delta
Deal found 1/26$274
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/136:04 pm
ROA
-
STL
1 stop5h 48m
American Airlines
Sun 2/156:38 pm
STL
-
ROA
1 stop4h 19m
American Airlines
Deal found 1/26$279
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/198:15 am
ROA
-
STL
1 stop5h 29m
American Airlines
Tue 3/318:00 am
STL
-
ROA
2 stops7h 33m
American Airlines
Deal found 1/26$302
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:50 pm
ROA
-
STL
1 stop4h 47m
Delta
Thu 7/235:30 pm
STL
-
ROA
1 stop5h 20m
Delta
Deal found 1/26$304
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/66:00 am
ROA
-
STL
1 stop4h 06m
Delta
Sun 3/86:59 pm
STL
-
ROA
1 stop4h 05m
Delta
Deal found 1/26$354
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:31 am
ROA
-
STL
1 stop4h 53m
American Airlines
Sun 5/176:27 am
STL
-
ROA
1 stop5h 06m
American Airlines
Deal found 1/25$376
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/157:51 pm
ROA
-
STL
1 stop5h 07m
Delta
Mon 3/306:59 pm
STL
-
ROA
1 stop4h 20m
Delta
Deal found 1/27$384
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/167:50 pm
ROA
-
STL
2 stops26h 17m
United Airlines
Tue 3/3110:00 am
STL
-
ROA
1 stop6h 05m
United Airlines
Deal found 1/27$394
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/157:05 am
ROA
-
STL
1 stop6h 38m
American Airlines
Mon 3/302:00 pm
STL
-
ROA
1 stop5h 30m
American Airlines
Deal found 1/26$412

Find flight deals from Roanoke to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$269
(Delta)

One-way from

$165
(American Airlines)

Popular in

May

Cheapest in

February

Average price

$322
Provider with most accurate pricing for Roanoke-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Roanoke-Lambert-St Louis flights.
Search Deals
From Roanoke to Lambert-St Louis
Search Deals
One-way flight from Roanoke to Lambert-St Louis
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($50 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from Roanoke to St. Louis that are best for you.

Fly from

Roanoke

Fly to

St. Louis

Route

Depart

Return

Price

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Thu 3/19

6:00 am-9:05 am

1 stop4h 05m

Lambert-St Louis

Tue 3/31

6:59 pm-12:04 am

1 stop4h 05m

$269

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Tue 3/17

7:51 pm-11:58 pm

1 stop5h 07m

Lambert-St Louis

Mon 3/30

6:59 pm-12:19 am

1 stop4h 20m

$269

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Mon 3/16

7:51 pm-11:58 pm

1 stop5h 07m

Lambert-St Louis

Tue 3/31

7:03 am-2:33 pm

1 stop6h 30m

$269

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Tue 2/17

6:00 am-9:06 am

1 stop4h 06m

Lambert-St Louis

Tue 2/24

5:00 pm-12:06 am

1 stop6h 06m

$269

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Tue 2/17

11:59 am-4:58 pm

1 stop5h 59m

Lambert-St Louis

Tue 2/24

8:00 am-4:33 pm

2 stops7h 33m

$274

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Wed 2/11

7:59 pm-11:37 pm

1 stop4h 38m

Lambert-St Louis

Mon 2/16

6:47 pm-12:06 am

1 stop4h 19m

$274

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Fri 2/13

6:04 pm-10:52 pm

1 stop5h 48m

Lambert-St Louis

Sun 2/15

6:38 pm-11:57 pm

1 stop4h 19m

$279

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Thu 3/19

8:15 am-12:44 pm

1 stop5h 29m

Lambert-St Louis

Tue 3/31

8:00 am-4:33 pm

2 stops7h 33m

$302

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Fri 3/6

6:00 am-9:06 am

1 stop4h 06m

Lambert-St Louis

Sun 3/8

6:59 pm-12:04 am

1 stop4h 05m

$354

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Mon 3/16

7:50 pm-9:07 pm

2 stops26h 17m

Lambert-St Louis

Tue 3/31

10:00 am-5:05 pm

1 stop6h 05m

$394

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/25

Showing 1-10 of 13 results
1
2

Compare providers for flights from Roanoke to St. Louis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Roanoke to St. Louis in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Roanoke-St. Louis flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Roanoke-St. Louis flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Roanoke-St. Louis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Roanoke-St. Louis flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Roanoke-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Roanoke to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to St. Louis

What is the cheapest month to book a flight from Roanoke to St. Louis?

Currently, February is the cheapest month in which you can book a flight from Roanoke to St. Louis (average of $216). Flying from Roanoke to St. Louis in November is currently the most expensive (average of $260). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated January 27, 2026.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Roanoke to St. Louis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,118 reviews

Crew

8.5

Food

7.2

Comfort

7.9

Overall

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,118 reviews
Delta
7.9
Good
8,118 reviews

Crew

8.5

Food

7.2

Comfort

7.9

Overall

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,205 reviews
Delta
7.9
Good
8,118 reviews

Crew

8.5

Food

7.2

Comfort

7.9

Overall

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,197 reviews
Delta
7.9
Good
8,118 reviews

Crew

8.5

Food

7.2

Comfort

7.9

Overall

7.9

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Roanoke to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Roanoke to St. Louis?

    Departing from Roanoke to St. Louis will take you 4h 05m. Airlines will cover a distance of 574 mi.

  • What are the cheapest airlines flying from Roanoke to St. Louis round-trip?

    Cheapflights users have booked flights from Roanoke to St. Louis round-trip from $248. Other airlines that can offer you cheap pricing are United Airlines, from $248, and Delta, from $248. These flights start at 28% lower than the current average price 3 months from now.

  • Can I find deals for flights from Roanoke to St. Louis that include hotel bookings?

    Yes. In addition to deals on Roanoke to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to St. Louis.

  • Can I find deals for business class flights from Roanoke to St. Louis?

    Yes. Cheapflights offers flight deals from Roanoke to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to St. Louis?

    Currently, February is the cheapest month in which you can book a flight from Roanoke to St. Louis (average of $216). Flying from Roanoke to St. Louis in November is currently the most expensive (average of $260). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Glencoe
Chesterfield
Alton
Farmington
Festus

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Alternative routes for Roanoke to St. Louis

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Top 3 airlines flying from Roanoke to St. Louis

Discover the top 3 airlines that operate flights from Roanoke to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$248Average$354FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$248Average$338FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$308FlexibilityNo cancel feeOn-timeN/A

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