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$239+ Cheap flights from Roanoke to St. Louis (ROA - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/25. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — STL
Aug 3 — Aug 101
Sun 8/3
Sun 8/10
1 adult, Economy
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Cheap flight deals from Roanoke to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Roanoke (ROA) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 29, 2025.

Round-trip from

$249
(Delta)

One-way from

$239
(American Airlines)

Popular in

May

Cheapest in

August

Average price

$338
From Roanoke to Lambert-St Louis
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One-way flight from Roanoke to Lambert-St Louis
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Highest demand for flights based on searches. 8% potential increase in price ($32 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Roanoke to St. Louis

Cheapest flights from Roanoke to St. Louis
Explore the most affordable flight options available from Roanoke to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/63:32 pmROA - STL
1 stop4h 35mDelta
Fri 9/126:42 pmSTL - ROA
1 stop4h 43mDelta
Deal found 7/29$249
This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/76:10 pmROA - STL
1 stop6h 43mAmerican Airlines
Sat 9/136:00 amSTL - ROA
1 stop7h 36mAmerican Airlines
Deal found 7/29$319
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/66:20 amROA - STL
2 stops10h 24mUnited Airlines
Fri 9/123:20 pmSTL - ROA
1 stop4h 59mUnited Airlines
Deal found 7/29$374

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
Use the filters below to find and compare flights from Roanoke to St. Louis that are best for you.

Fly from

Roanoke

Fly to

St. Louis

Route

Depart

Return

Price

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Sat 9/6

3:32 pm-7:07 pm

1 stop4h 35m

Lambert-St Louis

Fri 9/12

6:42 pm-12:25 am

1 stop4h 43m

$249

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Sun 9/7

6:10 pm-11:53 pm

1 stop6h 43m

Lambert-St Louis

Sat 9/13

6:00 am-2:36 pm

1 stop7h 36m

$319

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Sat 9/6

6:20 am-3:44 pm

2 stops10h 24m

Lambert-St Louis

Fri 9/12

3:20 pm-9:19 pm

1 stop4h 59m

$374

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Tue 11/25

8:06 pm-12:05 am

1 stop4h 59m

$239

RoanokeSt. Louis

ROA - STL

ROASTL

Roanoke

Tue 11/25

7:50 pm-6:47 pm

2 stops23h 57m

$507

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/27

Best time to book a flight from Roanoke to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to St. Louis

What is the cheapest month to book a flight from Roanoke to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Roanoke to St. Louis (average of $311). Flying from Roanoke to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ROA to STL?

Find hourly flight availability from Roanoke to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 29, 2025.

It’s optimal to fly from Roanoke to St. Louis in the evening. By choosing this option you can save up to 42% on the cost of your flight, compared to a flight in the afternoon.

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated July 29, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Roanoke to St. Louis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,977 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,977 reviews
Delta
8.0
Very good
7,977 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,899 reviews
Delta
8.0
Very good
7,977 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,977 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Comfort

7.9

Food

7.3

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Roanoke to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Roanoke to St. Louis round-trip?

    Cheapflights users have booked flights from Roanoke to St. Louis round-trip from $249. Other airlines that can offer you cheap pricing are American Airlines, from $319, and United Airlines, from $374. These flights start at 28% lower than the current average price 3 months from now.

  • Can I find deals for flights from Roanoke to St. Louis that include hotel bookings?

    Yes. In addition to deals on Roanoke to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to St. Louis.

  • Can I find deals for business class flights from Roanoke to St. Louis?

    Yes. Cheapflights offers flight deals from Roanoke to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from Roanoke to St. Louis (average of $311). Flying from Roanoke to St. Louis in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
O'Fallon
Maryland Heights
Fairview Heights
Collinsville
Eureka
St. Peters
Glencoe
Alton
Chesterfield
Festus
Farmington

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Top 3 airlines flying from Roanoke to St. Louis

Discover the top 3 airlines that operate flights from Roanoke to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$338FlexibilityNo cancel feeOn-time71%
DeltaCheapest$248Average$325FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$302Average$369FlexibilityNo cancel feeOn-time69%

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