How long is the flight from Portland, Maine to St. Louis?

A quick flight from Portland, Maine to St. Louis can take about 5h 17m. Delta provides one of the quickest options available for as low as $317. Portland, Maine and St. Louis are separated by a distance of 1092 mi. Both multi-stop and nonstop flights can be found to your destination and back.

What are the cheapest airlines flying from Portland, Maine to St. Louis round-trip?

Flying on Delta is currently your cheapest option to St. Louis, with prices starting at $158. Another option worth looking into is American Airlines, starting at $296 round trip. Delta is 63% cheaper than the average price of flights available within the next 90 days to this destination.

What are the cheapest airlines to fly from Portland, Maine to St. Louis one-way?

For one-way options, check prices for Delta. According to our data, you can fly for as low as $149. Users have also found prices from $163 and $198 on American Airlines and United Airlines, respectively.

In terms of precipitation, rainfall in St. Louis ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit St. Louis when rainfall is around 2.2 in.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Most accurate provider : When it comes to deals on Portland, Maine-St. Louis flights, users find the pricing of Gotogate to be most consistent on Cheapflights vs. Gotogate Users can find the same prices on Portland, Maine-St. Louis flight deals on Cheapflights vs. Gotogate >95% of the time. Price accuracy is based on data collected from Portland, Maine-St. Louis flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Portland, Maine-St. Louis flights, Cheapflights users trust Gotogate the most. Gotogate has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland, Maine-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Portland to St. Louis that include hotel bookings?

Yes. In addition to deals on Portland to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Portland to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to St. Louis.

Can I find deals for business class flights from Portland to St. Louis?

Yes. Cheapflights offers flight deals from Portland to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$240+ Flights from Portland, ME to St. Louis

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Cheap flight deals from Portland to St. Louis

Cheapest flights from Portland to St. Louis
Explore the most affordable flight options available from Portland to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Wed 12/1711:16 amPWM - STL

2 stops23h 24mMultiple Airlines

Thu 12/184:27 pmSTL - PWM

1 stop15h 39mMultiple Airlines

Deal found 12/11

$533

Tue 12/163:30 pmPWM - STL

1 stop7h 30mSouthwest

Thu 12/189:20 amSTL - PWM

1 stop4h 05mSouthwest

Deal found 12/11

$882

Tue 12/1611:27 amPWM - STL

2 stops8h 06mDelta

Thu 12/187:05 amSTL - PWM

2 stops7h 58mDelta

Deal found 12/11

$897

Best flights from Portland to St. Louis
Discover carefully curated flight deals from Portland to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 12, 2025.

Fri 1/2311:29 amPWM - STL

2 stops24h 42mMultiple Airlines

Sun 1/255:42 pmSTL - PWM

1 stop14h 25mMultiple Airlines

Deal found 12/10

$268

Thu 1/812:20 pmPWM - STL

1 stop5h 17mDelta

Tue 1/136:35 amSTL - PWM

1 stop4h 33mDelta

Deal found 12/10

$317

Mon 1/267:27 pmPWM - STL

1 stop5h 32mUnited Airlines

Wed 1/288:30 amSTL - PWM

1 stop5h 01mUnited Airlines

Deal found 12/10

$317

Mon 1/265:45 amPWM - STL

2 stops8h 00mSouthwest

Wed 1/286:50 amSTL - PWM

1 stop4h 20mSouthwest

Deal found 12/10

$322

Sat 1/174:10 pmPWM - STL

1 stop6h 03mUnited Airlines

Tue 1/206:30 amSTL - PWM

1 stop7h 09mUnited Airlines

Deal found 12/9

$361

Last-minute flights from Portland to St. Louis
Discover last-minute flight deals from Portland to St. Louis. Data last updated December 12, 2025 and is based on user searches.

Thu 1/812:20 pmPWM - STL

1 stop5h 17mDelta

Tue 1/136:35 amSTL - PWM

1 stop4h 33mDelta

Deal found 12/10

$317

Sun 1/115:30 amPWM - STL

1 stop6h 35mDelta

Mon 1/123:45 pmSTL - PWM

2 stops7h 35mDelta

Deal found 12/11

$376

Sun 1/115:35 amPWM - STL

2 stops9h 35mSouthwest

Mon 1/1211:35 amSTL - PWM

2 stops9h 40mSouthwest

Deal found 12/11

$410

Sat 1/174:10 pmPWM - STL

1 stop6h 03mUnited Airlines

Tue 1/206:30 amSTL - PWM

1 stop7h 09mUnited Airlines

Deal found 12/9

$361

Fri 1/2311:29 amPWM - STL

2 stops24h 42mMultiple Airlines

Sun 1/255:42 pmSTL - PWM

1 stop14h 25mMultiple Airlines

Deal found 12/10

$268

Sat 1/246:00 amPWM - STL

1 stop5h 41mUnited Airlines

Sat 1/316:30 amSTL - PWM

1 stop7h 09mUnited Airlines

Deal found 12/10

$415

One-way flights from Portland to St. Louis
Search for one-way flight options from Portland to St. Louis. Find affordable one-way fares based on user searches. Data last updated December 12, 2025.

Fri 1/25:45 amPWM - STL

1 stop7h 36mDelta

Deal found 12/10

$240

Fri 1/210:19 amPWM - STL

2 stops8h 35mUnited Airlines

Deal found 12/10

$259

Fri 1/25:30 amPWM - STL

2 stops6h 55mSouthwest

Deal found 12/10

$302

Sat 1/35:15 amPWM - STL

2 stops9h 10mSouthwest

Deal found 12/10

$315

Fri 1/29:46 amPWM - STL

1 stop13h 47mMultiple Airlines

Deal found 12/10

$323

Sun 1/45:45 amPWM - STL

1 stop7h 47mAmerican Airlines

Deal found 12/10

$350

Sat 1/311:16 amPWM - STL

3 stops45h 56mMultiple Airlines

Deal found 12/11

$354

Sat 1/34:48 pmPWM - STL

1 stop4h 53mDelta

Deal found 12/10

$370

Find flight deals from Portland to St. Louis

Most accurate provider	Gotogate 3 stars
Most trusted provider	Gotogate 3 stars
Round-trip from	$268 (Kiwi.com)
One-way from	$240 (Delta)
Popular in	December
Cheapest in	February
Average price	$791

Provider with most accurate pricing for Portland-Lambert-St Louis flight deals.

Search Deals

Provider most trusted by Cheapflights users for Portland-Lambert-St Louis flights.

Search Deals

From Portland to Lambert-St Louis

Search Deals

One-way flight from Portland to Lambert-St Louis

Search Deals

Highest demand for flights based on searches. 26% potential increase in price ($156 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 7% potential price decrease ($33 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Portland to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Fri 1/23

11:29 am-11:11 am

2 stops24h 42m

Lambert-St Louis

Sun 1/25

5:42 pm-9:07 am

1 stop14h 25m

$268

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Thu 1/8

12:20 pm-4:37 pm

1 stop5h 17m

Lambert-St Louis

Tue 1/13

6:35 am-12:08 pm

1 stop4h 33m

$317

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Mon 1/26

7:27 pm-11:59 pm

1 stop5h 32m

Lambert-St Louis

Wed 1/28

8:30 am-2:31 pm

1 stop5h 01m

$317

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Mon 1/26

5:45 am-12:45 pm

2 stops8h 00m

Lambert-St Louis

Wed 1/28

6:50 am-12:10 pm

1 stop4h 20m

$322

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Sat 1/17

4:10 pm-9:13 pm

1 stop6h 03m

Lambert-St Louis

Tue 1/20

6:30 am-2:39 pm

1 stop7h 09m

$361

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Fri 1/2

5:45 am-12:21 pm

1 stop7h 36m

$240

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Fri 1/2

10:19 am-5:54 pm

2 stops8h 35m

$259

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Fri 1/2

5:30 am-11:25 am

2 stops6h 55m

$302

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Sat 1/3

5:15 am-3:05 pm

1 stop10h 50m

$302

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Fri 1/2

9:46 am-10:33 pm

1 stop13h 47m

$323

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 11 results

Compare providers for flights from Portland to St. Louis

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to St. Louis in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars
Gotogate	Price Accuracy3 stars	Trust Score*3 stars
Mytrip	Price Accuracy3 stars	Trust Score*3 stars
Cheapfaremart	Price Accuracy-	Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Portland, Maine-St. Louis flights, users find the pricing of Gotogate to be most consistent on Cheapflights vs. Gotogate Users can find the same prices on Portland, Maine-St. Louis flight deals on Cheapflights vs. Gotogate >95% of the time. Price accuracy is based on data collected from Portland, Maine-St. Louis flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Portland, Maine-St. Louis flights, Cheapflights users trust Gotogate the most. Gotogate has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland, Maine-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Portland to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Portland with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to St. Louis

What is the cheapest month to book a flight from Portland, Maine to St. Louis?

Currently, December is the cheapest month in which you can book a flight from Portland, Maine to St. Louis (average of $107). Flying from Portland, Maine to St. Louis in July is currently the most expensive (average of $316). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PWM to STL?

When flying from Portland, Maine to St. Louis, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 60% versus a flight at noon.

Reviews of airlines servicing St. Louis

Get a feel of what it's like to fly with Delta and American Airlines from Portland to St. Louis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.9

Good

8,007 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Delta

7.9

Good

8,007 reviews

Delta

7.9

Good

8,007 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

American Airlines

7.2

Good

11,050 reviews

Delta

7.9

Good

8,007 reviews

Reviews

1 / 20

6.0

Good

Jim,Nov 2025

AVL - ATL

Related info for your journey

How long is the flight from Portland, Maine to St. Louis?
A quick flight from Portland, Maine to St. Louis can take about 5h 17m. Delta provides one of the quickest options available for as low as $317. Portland, Maine and St. Louis are separated by a distance of 1092 mi. Both multi-stop and nonstop flights can be found to your destination and back.
What are the cheapest airlines flying from Portland, Maine to St. Louis round-trip?
Flying on Delta is currently your cheapest option to St. Louis, with prices starting at $158. Another option worth looking into is American Airlines, starting at $296 round trip. Delta is 63% cheaper than the average price of flights available within the next 90 days to this destination.
What are the cheapest airlines to fly from Portland, Maine to St. Louis one-way?
For one-way options, check prices for Delta. According to our data, you can fly for as low as $149. Users have also found prices from $163 and $198 on American Airlines and United Airlines, respectively.
Can I find deals for flights from Portland to St. Louis that include hotel bookings?
Yes. In addition to deals on Portland to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Portland to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to St. Louis.
Can I find deals for business class flights from Portland to St. Louis?
Yes. Cheapflights offers flight deals from Portland to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Portland, Maine to St. Louis?
Currently, December is the cheapest month in which you can book a flight from Portland, Maine to St. Louis (average of $107). Flying from Portland, Maine to St. Louis in July is currently the most expensive (average of $316). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Other flights to St. Louis

Top 2 airlines flying from Portland to St. Louis

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$236	Average$385	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$296	Average$464	FlexibilityNo cancel fee	On-time71%

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$240+ Cheap flights from Portland, ME to St. Louis (PWM - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/2. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Portland to St. Louis with Cheapflights

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2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Portland to St. Louis

Cheapest flights from Portland to St. LouisExplore the most affordable flight options available from Portland to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Explore the most affordable flight options available from Portland to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Find flight deals from Portland to St. Louis

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Portland to St. Louis that are best for you.

Compare providers for flights from Portland to St. Louis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to St. Louis in December.

Best time to book a flight from Portland to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Portland with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Portland to St. Louis

What is the cheapest month to book a flight from Portland, Maine to St. Louis?

What is the cheapest time of day to fly from PWM to STL?

Reviews of airlines servicing St. Louis

Get a feel of what it's like to fly with Delta and American Airlines from Portland to St. Louis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Portland to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Portland, Maine to St. Louis?

What are the cheapest airlines flying from Portland, Maine to St. Louis round-trip?

What are the cheapest airlines to fly from Portland, Maine to St. Louis one-way?

Can I find deals for flights from Portland to St. Louis that include hotel bookings?

How can I find direct flights from Portland to St. Louis?

Can I find deals for business class flights from Portland to St. Louis?

What is the cheapest month to book a flight from Portland, Maine to St. Louis?

Traveling to a place near St. Louis?

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Alternative routes for Portland to St. Louis

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Top 2 airlines flying from Portland to St. Louis

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Cheapest flights from Portland to St. Louis
Explore the most affordable flight options available from Portland to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.