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$204+ Cheap flights from Portland, ME to St. Louis (PWM - STL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/25. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — STL
Nov 27 — Dec 41
Thu 11/27
Thu 12/4
1 adult, Economy
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Find flight deals from Portland to St. Louis

Cheapest flights from Portland to St. Louis
Explore the most affordable flight options available from Portland to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 28, 2025.

This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:00 amPWM - STL
1 stop7h 40mDelta
Wed 12/35:15 pmSTL - PWM
1 stop5h 06mDelta
Deal found 10/26$299
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:00 amPWM - STL
1 stop7h 40mDelta
Fri 12/54:32 pmSTL - PWM
1 stop6h 27mDelta
Deal found 10/26$301
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/25:21 pmPWM - STL
1 stop5h 26mAmerican Airlines
Thu 12/46:00 amSTL - PWM
1 stop4h 37mAmerican Airlines
Deal found 10/26$318
This Kiwi.com deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/89:46 amPWM - STL
1 stop13h 47mMultiple Airlines
Thu 12/1112:04 pmSTL - PWM
2 stops21h 37mMultiple Airlines
Deal found 10/27$333
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/93:30 pmPWM - STL
1 stop7h 30mSouthwest
Thu 12/117:00 amSTL - PWM
2 stops6h 55mSouthwest
Deal found 10/27$344
This Southwest deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/23:30 pmPWM - STL
1 stop7h 30mSouthwest
Thu 12/41:20 pmSTL - PWM
2 stops7h 55mSouthwest
Deal found 10/26$347
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/216:00 amPWM - STL
1 stop8h 00mDelta
Mon 11/242:00 pmSTL - PWM
1 stop7h 19mDelta
Deal found 10/27$349
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/311:16 amPWM - STL
1 stop12h 17mMultiple Airlines
Thu 12/412:04 pmSTL - PWM
2 stops21h 37mMultiple Airlines
Deal found 10/26$356
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/24:53 pmPWM - STL
1 stop4h 54mDelta
Wed 12/36:39 amSTL - PWM
1 stop4h 34mDelta
Deal found 10/26$368
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/24:53 pmPWM - STL
1 stop4h 54mDelta
Fri 12/54:32 pmSTL - PWM
1 stop6h 27mDelta
Deal found 10/26$370
This Southwest deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/215:30 amPWM - STL
2 stops9h 05mSouthwest
Mon 11/245:05 pmSTL - PWM
1 stop6h 15mSouthwest
Deal found 10/27$400

Cheap flight deals from Portland to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Portland (PWM) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 28, 2025.

Most accurate provider

Gotogate
3 stars

Most trusted provider

Gotogate
3 stars

Round-trip from

$299
(Delta)

One-way from

$204
(United Airlines)

Popular in

December

Cheapest in

February

Average price

$364
Provider with most accurate pricing for Portland-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Portland-Lambert-St Louis flights.
Search Deals
From Portland to Lambert-St Louis
Search Deals
One-way flight from Portland to Lambert-St Louis
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($55 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Portland to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
Use the filters below to find and compare flights from Portland to St. Louis that are best for you.

Fly from

Portland

Fly to

St. Louis

Route

Depart

Return

Price

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Tue 12/9

7:00 am-1:18 pm

1 stop7h 18m

Lambert-St Louis

Thu 12/11

9:53 am-4:28 pm

1 stop5h 35m

$299

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Wed 12/3

6:00 am-12:40 pm

1 stop7h 40m

Lambert-St Louis

Wed 12/3

5:15 pm-11:21 pm

1 stop5h 06m

$299

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Mon 12/8

5:17 pm-9:47 pm

1 stop5h 30m

Lambert-St Louis

Thu 12/11

9:53 am-4:28 pm

1 stop5h 35m

$299

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Wed 12/3

4:53 pm-8:47 pm

1 stop4h 54m

Lambert-St Louis

Thu 12/4

6:39 am-12:13 pm

1 stop4h 34m

$299

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Wed 12/3

6:00 am-12:40 pm

1 stop7h 40m

Lambert-St Louis

Fri 12/5

4:32 pm-11:59 pm

1 stop6h 27m

$301

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Tue 12/2

5:21 pm-9:47 pm

1 stop5h 26m

Lambert-St Louis

Thu 12/4

6:00 am-11:37 am

1 stop4h 37m

$318

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Tue 12/9

3:30 pm-10:00 pm

1 stop7h 30m

Lambert-St Louis

Thu 12/11

7:00 am-2:55 pm

2 stops6h 55m

$344

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Tue 12/2

3:30 pm-10:00 pm

1 stop7h 30m

Lambert-St Louis

Thu 12/4

1:20 pm-10:15 pm

2 stops7h 55m

$347

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Fri 11/21

6:00 am-1:00 pm

1 stop8h 00m

Lambert-St Louis

Mon 11/24

2:00 pm-10:19 pm

1 stop7h 19m

$349

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Tue 11/25

9:45 am-3:46 pm

1 stop7h 01m

$204

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Showing 1-10 of 16 results
1
2

Compare providers for flights from Portland to St. Louis

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to St. Louis in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
GotogatePrice Accuracy3 starsTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars
CheapfaremartPrice Accuracy-Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Portland, Maine-St. Louis flights, users find the pricing of Gotogate to be most consistent on Cheapflights vs. Gotogate Users can find the same prices on Portland, Maine-St. Louis flight deals on Cheapflights vs. Gotogate >95% of the time. Price accuracy is based on data collected from Portland, Maine-St. Louis flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Portland, Maine-St. Louis flights, Cheapflights users trust Gotogate the most. Gotogate has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland, Maine-St. Louis flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Portland to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Portland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Portland to St. Louis

What is the cheapest month to book a flight from Portland, Maine to St. Louis?

Currently, December is the cheapest month in which you can book a flight from Portland, Maine to St. Louis (average of $107). Flying from Portland, Maine to St. Louis in July is currently the most expensive (average of $319). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PWM to STL?

Find hourly flight availability from Portland to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 28, 2025.

When flying from Portland, Maine to St. Louis, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 60% versus a flight at noon.

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated October 28, 2025.
Get a feel of what it's like to fly with Southwest, Delta, and American Airlines from Portland to St. Louis by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,240 reviews

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,240 reviews
Southwest
8.0
Very good
4,240 reviews

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
7,994 reviews
Southwest
8.0
Very good
4,240 reviews

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,032 reviews
Southwest
8.0
Very good
4,240 reviews

Boarding

8.1

Comfort

8.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Food

7.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Portland to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Portland, Maine to St. Louis?

    A quick flight from Portland, Maine to St. Louis can take about 7h 18m. American Airlines provides one of the quickest options available for as low as $299. Portland, Maine and St. Louis are separated by a distance of 1092 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Portland, Maine to St. Louis round-trip?

    Flying on Delta is currently your cheapest option to St. Louis, with prices starting at $236. Additional round-trip tickets that might be worth considering are offered by American Airlines and Southwest, with the lowest prices starting at $300 and $371, respectively. Delta is 41% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Portland, Maine to St. Louis one-way?

    For one-way options, check prices for United Airlines. According to our data, you can fly for as low as $204. Users have also found prices from $214 and $214 on American Airlines and Delta, respectively.

  • Can I find deals for flights from Portland to St. Louis that include hotel bookings?

    Yes. In addition to deals on Portland to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Portland to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Portland to St. Louis.

  • Can I find deals for business class flights from Portland to St. Louis?

    Yes. Cheapflights offers flight deals from Portland to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Portland, Maine to St. Louis?

    Currently, December is the cheapest month in which you can book a flight from Portland, Maine to St. Louis (average of $107). Flying from Portland, Maine to St. Louis in July is currently the most expensive (average of $319). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Edwardsville
O'Fallon
Fairview Heights
Maryland Heights
Collinsville
Eureka
Glencoe
St. Peters
Chesterfield
Alton
Farmington
Festus

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Portland to St. Louis

Discover the top 3 airlines that operate flights from Portland to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$236Average$385FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$300Average$462FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$371Average$417FlexibilityNo cancel feeOn-time63%

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